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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for RELA

Z-value: 0.63

Motif logo

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
RELA
ENSG00000173039.14 RELA proto-oncogene, NF-kB subunit

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_65429318_65430091RELA1950.869044-0.422.6e-01Click!
chr11_65430100_65430433RELA20.946657-0.235.5e-01Click!
chr11_65430663_65431111RELA3220.764562-0.186.5e-01Click!
chr11_65431137_65431406RELA7060.4610780.078.7e-01Click!

Activity of the RELA motif across conditions

Conditions sorted by the z-value of the RELA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_8000859_8001010 0.47 TNFRSF9
 tumor necrosis factor receptor superfamily, member 9
 8
 0.98
chr22_30475055_30475206 0.32 HORMAD2
 HORMA domain containing 2
 1033
 0.38
chrX_40429955_40430133 0.30 ATP6AP2
 ATPase, H+ transporting, lysosomal accessory protein 2
 10102
 0.21
chr20_4795121_4795462 0.26 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 478
 0.82
chr12_42958835_42958986 0.24 PRICKLE1
 prickle homolog 1 (Drosophila)
 24568
 0.21
chr14_94425760_94425911 0.24 ASB2
 ankyrin repeat and SOCS box containing 2
 2068
 0.26
chr7_128578118_128579002 0.22 IRF5
 interferon regulatory factor 5
 289
 0.89
chr6_20202498_20202689 0.22 RP11-239H6.2
9725
 0.23
chr15_69083910_69084061 0.22 ENSG00000265195
 .
 10279
 0.23
chr4_100738641_100738957 0.21 DAPP1
 dual adaptor of phosphotyrosine and 3-phosphoinositides
 796
 0.72
chrX_53741093_53741244 0.21 HUWE1
 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
 27495
 0.23
chr20_5296763_5297139 0.21 PROKR2
 prokineticin receptor 2
 427
 0.87
chr10_65021596_65021747 0.21 JMJD1C
 jumonji domain containing 1C
 7155
 0.29
chr2_38265076_38265999 0.21 RMDN2-AS1
 RMDN2 antisense RNA 1
 2053
 0.33
chr2_214108249_214108400 0.21 SPAG16
 sperm associated antigen 16
 40789
 0.21
chr20_50141923_50142074 0.21 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 17260
 0.25
chr17_47572677_47573321 0.20 NGFR
 nerve growth factor receptor
 344
 0.86
chr3_71833354_71833608 0.19 PROK2
 prokineticin 2
 731
 0.68
chr2_113932280_113932569 0.19 AC016683.5
490
 0.59
chr14_66694537_66694688 0.18 ENSG00000200860
 .
 50259
 0.19
chr5_150473764_150473973 0.18 TNIP1
 TNFAIP3 interacting protein 1
 730
 0.68
chr8_126964027_126964178 0.18 ENSG00000206695
 .
 50907
 0.19
chr9_123690633_123691433 0.18 TRAF1
 TNF receptor-associated factor 1
 14
 0.98
chrX_9979270_9979421 0.18 WWC3
 WWC family member 3
 4257
 0.22
chr5_49962630_49963750 0.18 PARP8
 poly (ADP-ribose) polymerase family, member 8
 201
 0.97
chr2_219745053_219745526 0.18 WNT10A
 wingless-type MMTV integration site family, member 10A
 204
 0.9
chr15_45409056_45409207 0.17 DUOX2
 dual oxidase 2
 2589
 0.14
chr13_46739755_46739906 0.17 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 2824
 0.22
chr1_9688741_9688898 0.17 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 22971
 0.15
chr6_138028959_138029110 0.17 ENSG00000216097
 .
 9051
 0.27
chr3_142800787_142800938 0.17 CHST2
 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
 37311
 0.15
chr15_31638589_31638828 0.17 KLF13
 Kruppel-like factor 13
 6572
 0.32
chr16_28996496_28996848 0.16 LAT
 linker for activation of T cells
 11
 0.94
chr2_164608573_164608724 0.16 FIGN
 fidgetin
 16126
 0.31
chr17_72735282_72735631 0.16 RAB37
 RAB37, member RAS oncogene family
 2085
 0.18
chr14_22994691_22994955 0.16 TRAJ15
 T cell receptor alpha joining 15
 3757
 0.14
chr7_30766706_30766866 0.16 INMT
 indolethylamine N-methyltransferase
 24965
 0.16
chr4_105982370_105982725 0.16 ENSG00000252136
 .
 44597
 0.16
chr12_62996165_62996975 0.16 RP11-631N16.2
38
 0.9
chr1_112159044_112159195 0.16 RAP1A
 RAP1A, member of RAS oncogene family
 3280
 0.23
chr2_10548224_10548465 0.16 HPCAL1
 hippocalcin-like 1
 11803
 0.19
chr19_54672117_54672268 0.16 TMC4
 transmembrane channel-like 4
 4255
 0.08
chr2_10169297_10169448 0.16 KLF11
 Kruppel-like factor 11
 13604
 0.13
chr19_45271245_45271464 0.15 ENSG00000253027
 .
 3147
 0.15
chr1_93443435_93443586 0.15 ENSG00000239710
 .
 2830
 0.16
chr3_195913428_195913625 0.15 ENSG00000222335
 .
 15694
 0.13
chr16_68798920_68799109 0.15 ENSG00000200558
 .
 22631
 0.14
chr5_1105065_1105874 0.15 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 6681
 0.19
chr8_37751638_37751789 0.15 RAB11FIP1
 RAB11 family interacting protein 1 (class I)
 5259
 0.15
chr15_31555832_31555983 0.15 KLF13
 Kruppel-like factor 13
 63151
 0.13
chr9_123688442_123688941 0.15 TRAF1
 TNF receptor-associated factor 1
 2356
 0.33
chr9_139927070_139927409 0.14 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 223
 0.78
chr6_3876229_3876380 0.14 FAM50B
 family with sequence similarity 50, member B
 26682
 0.18
chr13_74807358_74807666 0.14 ENSG00000206617
 .
 55839
 0.16
chr17_46187551_46187761 0.14 SNX11
 sorting nexin 11
 1655
 0.23
chr17_38024211_38024362 0.14 ZPBP2
 zona pellucida binding protein 2
 131
 0.95
chr17_66286056_66286766 0.14 SLC16A6
 solute carrier family 16, member 6
 846
 0.47
chr16_89690039_89690304 0.14 DPEP1
 dipeptidase 1 (renal)
 3171
 0.14
chrX_123373984_123374135 0.14 ENSG00000252693
 .
 42466
 0.19
chr10_90753077_90753312 0.14 ACTA2
 actin, alpha 2, smooth muscle, aorta
 2047
 0.24
chr7_36640832_36640983 0.14 AOAH-IT1
 AOAH intronic transcript 1 (non-protein coding)
 1181
 0.5
chr1_150737104_150737638 0.14 CTSS
 cathepsin S
 897
 0.5
chr21_30464791_30465071 0.13 MAP3K7CL
 MAP3K7 C-terminal like
 356
 0.83
chr5_134879321_134879990 0.13 NEUROG1
 neurogenin 1
 8016
 0.18
chr1_147229260_147229411 0.13 RP11-433J22.2
91
 0.97
chr3_131105945_131106096 0.13 NUDT16
 nudix (nucleoside diphosphate linked moiety X)-type motif 16
 5391
 0.18
chr20_34674700_34674851 0.13 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
 4651
 0.22
chr15_86127194_86127729 0.13 RP11-815J21.2
4052
 0.21
chr11_121323015_121324255 0.13 RP11-730K11.1
7
 0.95
chr21_40275169_40275320 0.13 ENSG00000272015
 .
 8535
 0.29
chr1_31227757_31227908 0.13 LAPTM5
 lysosomal protein transmembrane 5
 2835
 0.23
chr1_199997854_199998005 0.13 NR5A2
 nuclear receptor subfamily 5, group A, member 2
 918
 0.55
chr14_90798758_90798909 0.13 NRDE2
 NRDE-2, necessary for RNA interference, domain containing
 352
 0.89
chr7_74057672_74058172 0.13 GTF2I
 general transcription factor IIi
 14089
 0.22
chr1_166459489_166459697 0.13 FAM78B
 family with sequence similarity 78, member B
 323387
 0.01
chr9_134143747_134144006 0.13 FAM78A
 family with sequence similarity 78, member A
 2004
 0.31
chr12_120679359_120679510 0.12 PXN
 paxillin
 8530
 0.12
chrX_128915626_128915992 0.12 SASH3
 SAM and SH3 domain containing 3
 1849
 0.35
chr11_27435035_27435186 0.12 CCDC34
 coiled-coil domain containing 34
 49695
 0.12
chr17_38480138_38480579 0.12 RARA
 retinoic acid receptor, alpha
 5821
 0.12
chr14_77499378_77500437 0.12 IRF2BPL
 interferon regulatory factor 2 binding protein-like
 4873
 0.22
chr11_114217713_114217864 0.12 RP11-64D24.2
9505
 0.18
chr15_81586254_81586487 0.12 IL16
 interleukin 16
 2884
 0.28
chr20_47441337_47441845 0.12 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 2829
 0.36
chr10_6243545_6244657 0.12 RP11-414H17.5
555
 0.52
chr12_22695256_22695407 0.12 C2CD5
 C2 calcium-dependent domain containing 5
 1856
 0.46
chrX_48793999_48794379 0.12 PIM2
 pim-2 oncogene
 17888
 0.08
chrX_41301243_41301541 0.12 NYX
 nyctalopin
 5295
 0.25
chr7_26333293_26333815 0.11 SNX10
 sorting nexin 10
 880
 0.67
chr1_65430726_65432146 0.11 JAK1
 Janus kinase 1
 751
 0.73
chr6_106808594_106809355 0.11 RP11-404H14.1
1382
 0.42
chr9_134604865_134605016 0.11 ENSG00000240853
 .
 4086
 0.24
chr8_144512945_144513817 0.11 MAFA
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
 805
 0.48
chr21_39867301_39867487 0.11 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 2951
 0.4
chr4_17809379_17809707 0.11 DCAF16
 DDB1 and CUL4 associated factor 16
 2838
 0.25
chr6_1014051_1014202 0.11 AL033381.1
 Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
 66038
 0.14
chr22_42815517_42815668 0.11 NFAM1
 NFAT activating protein with ITAM motif 1
 12809
 0.19
chr6_132113440_132113591 0.11 ENSG00000266807
 .
 203
 0.94
chr9_132650035_132650502 0.11 FNBP1
 formin binding protein 1
 31321
 0.13
chr3_16156075_16156226 0.11 GALNT15
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
 60006
 0.14
chr15_41234314_41234975 0.11 CHAC1
 ChaC, cation transport regulator homolog 1 (E. coli)
 10516
 0.12
chr2_33537454_33537605 0.11 LTBP1
 latent transforming growth factor beta binding protein 1
 10932
 0.2
chr10_3848477_3848747 0.11 KLF6
 Kruppel-like factor 6
 21139
 0.22
chr18_59519452_59519603 0.11 RNF152
 ring finger protein 152
 41465
 0.22
chr17_67322489_67323211 0.11 ABCA5
 ATP-binding cassette, sub-family A (ABC1), member 5
 381
 0.89
chr11_69457554_69457705 0.11 CCND1
 cyclin D1
 1655
 0.41
chr1_226922169_226922483 0.11 ITPKB
 inositol-trisphosphate 3-kinase B
 2833
 0.32
chr12_111842372_111842523 0.11 SH2B3
 SH2B adaptor protein 3
 1305
 0.45
chr1_37945353_37945703 0.11 ZC3H12A
 zinc finger CCCH-type containing 12A
 1763
 0.28
chr19_50400390_50400724 0.11 IL4I1
 interleukin 4 induced 1
 345
 0.67
chr1_143743180_143744039 0.11 RP6-206I17.4
23905
 0.15
chr6_72155810_72156092 0.11 ENSG00000207827
 .
 42627
 0.16
chr12_111115977_111116128 0.11 HVCN1
 hydrogen voltage-gated channel 1
 10462
 0.16
chr15_42349005_42349667 0.11 PLA2G4E
 phospholipase A2, group IVE
 5948
 0.18
chr18_59619511_59619683 0.10 RNF152
 ring finger protein 152
 58133
 0.16
chr19_10341031_10341948 0.10 ENSG00000264266
 .
 400
 0.34
chr15_91807157_91807528 0.10 SV2B
 synaptic vesicle glycoprotein 2B
 38242
 0.2
chr8_142138821_142140144 0.10 RP11-809O17.1
578
 0.46
chr2_219744680_219744914 0.10 WNT10A
 wingless-type MMTV integration site family, member 10A
 288
 0.85
chr22_22005684_22006266 0.10 ENSG00000212102
 .
 1295
 0.23
chr8_59717634_59717850 0.10 ENSG00000201231
 .
 9369
 0.29
chr6_37592383_37592534 0.10 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 21692
 0.22
chr17_56230401_56230552 0.10 OR4D1
 olfactory receptor, family 4, subfamily D, member 1
 2018
 0.26
chr6_75458992_75459143 0.10 ENSG00000264884
 .
 29508
 0.26
chr17_7152312_7152463 0.10 CTDNEP1
 CTD nuclear envelope phosphatase 1
 1729
 0.12
chr10_91093714_91093865 0.10 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
 1548
 0.3
chr7_139930052_139930405 0.10 ENSG00000199283
 .
 11442
 0.17
chr18_42306038_42306201 0.10 SETBP1
 SET binding protein 1
 28990
 0.26
chr12_56881156_56881307 0.10 GLS2
 glutaminase 2 (liver, mitochondrial)
 671
 0.58
chr14_93427433_93427584 0.10 CHGA
 chromogranin A (parathyroid secretory protein 1)
 37987
 0.18
chr1_154300198_154300512 0.10 ATP8B2
 ATPase, aminophospholipid transporter, class I, type 8B, member 2
 79
 0.94
chr19_1074414_1074782 0.10 HMHA1
 histocompatibility (minor) HA-1
 2844
 0.13
chr18_72912801_72912952 0.10 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
 4592
 0.28
chr19_46283149_46283300 0.10 DMPK
 dystrophia myotonica-protein kinase
 575
 0.52
chr1_247354543_247354824 0.10 MIR3916
 microRNA 3916
 8815
 0.14
chr9_92218215_92218814 0.10 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 1414
 0.56
chr21_45564255_45564539 0.10 C21orf33
 chromosome 21 open reading frame 33
 8396
 0.15
chr20_43597999_43598419 0.10 STK4
 serine/threonine kinase 4
 3042
 0.19
chr10_63595750_63596410 0.10 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 64979
 0.13
chr4_113205771_113206741 0.10 TIFA
 TRAF-interacting protein with forkhead-associated domain
 803
 0.58
chr2_145116612_145116763 0.10 GTDC1
 glycosyltransferase-like domain containing 1
 26604
 0.24
chr7_4817960_4818111 0.10 AP5Z1
 adaptor-related protein complex 5, zeta 1 subunit
 2771
 0.22
chr1_51442471_51443647 0.10 CDKN2C
 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
 7443
 0.21
chr2_47796814_47797322 0.10 KCNK12
 potassium channel, subfamily K, member 12
 1010
 0.5
chr2_106363775_106364396 0.10 NCK2
 NCK adaptor protein 2
 1897
 0.48
chr1_167599991_167600483 0.10 RP3-455J7.4
326
 0.69
chr19_38908265_38908571 0.09 RASGRP4
 RAS guanyl releasing protein 4
 8384
 0.09
chr9_117145261_117145418 0.09 AKNA
 AT-hook transcription factor
 4904
 0.23
chr2_192058910_192059074 0.09 STAT4
 signal transducer and activator of transcription 4
 42670
 0.15
chr5_149461865_149462126 0.09 CSF1R
 colony stimulating factor 1 receptor
 3995
 0.18
chr18_2656091_2657266 0.09 SMCHD1
 structural maintenance of chromosomes flexible hinge domain containing 1
 792
 0.58
chr8_28205045_28205788 0.09 ZNF395
 zinc finger protein 395
 3667
 0.19
chr19_49839028_49839359 0.09 CD37
 CD37 molecule
 472
 0.63
chr10_79050334_79050485 0.09 RP11-328K22.1
23290
 0.23
chr22_33278140_33278291 0.09 TIMP3
 TIMP metallopeptidase inhibitor 3
 80528
 0.1
chr20_47884918_47885071 0.09 ZNFX1
 zinc finger, NFX1-type containing 1
 2766
 0.18
chr20_3888044_3888195 0.09 ENSG00000199024
 .
 10022
 0.14
chr1_36816210_36816695 0.09 STK40
 serine/threonine kinase 40
 10489
 0.13
chr2_234293590_234293937 0.09 DGKD
 diacylglycerol kinase, delta 130kDa
 828
 0.57
chr6_144017218_144017369 0.09 PHACTR2
 phosphatase and actin regulator 2
 18088
 0.25
chr4_152331308_152331459 0.09 FAM160A1
 family with sequence similarity 160, member A1
 879
 0.7
chr12_806850_807001 0.09 NINJ2
 ninjurin 2
 33980
 0.14
chr19_39106930_39107372 0.09 MAP4K1
 mitogen-activated protein kinase kinase kinase kinase 1
 1413
 0.27
chr2_201987300_201987657 0.09 CFLAR
 CASP8 and FADD-like apoptosis regulator
 278
 0.87
chr20_1309605_1309756 0.09 SDCBP2
 syndecan binding protein (syntenin) 2
 203
 0.91
chr6_15309152_15309303 0.09 ENSG00000201367
 .
 5924
 0.22
chr11_71826248_71826399 0.09 ANAPC15
 anaphase promoting complex subunit 15
 2497
 0.13
chr9_114792415_114792566 0.09 RP11-4O1.2
6100
 0.22
chr17_37793084_37793352 0.09 STARD3
 StAR-related lipid transfer (START) domain containing 3
 100
 0.94
chr1_27070439_27070710 0.09 ARID1A
 AT rich interactive domain 1A (SWI-like)
 14703
 0.13
chr7_29283709_29283860 0.09 AC004593.3
35198
 0.16
chrX_39473449_39473600 0.09 ENSG00000263730
 .
 46946
 0.2
chrX_30594869_30596024 0.09 CXorf21
 chromosome X open reading frame 21
 515
 0.84
chr15_45027870_45028221 0.09 TRIM69
 tripartite motif containing 69
 515
 0.75
chr1_203259093_203259633 0.09 BTG2
 BTG family, member 2
 15301
 0.16
chr9_37036694_37037719 0.09 PAX5
 paired box 5
 3103
 0.27
chr7_74194192_74194343 0.09 NCF1
 neutrophil cytosolic factor 1
 2654
 0.28
chr20_11435441_11435592 0.09 ENSG00000222281
 .
 364223
 0.01
chr11_14468343_14468494 0.09 ENSG00000251991
 .
 32020
 0.18
chr1_182583862_182584759 0.09 RGS16
 regulator of G-protein signaling 16
 10767
 0.21
chr19_35940283_35940434 0.09 FFAR2
 free fatty acid receptor 2
 259
 0.87
chr9_72725675_72725941 0.09 MAMDC2-AS1
 MAMDC2 antisense RNA 1
 2968
 0.33
chr3_33800152_33800303 0.08 PDCD6IP
 programmed cell death 6 interacting protein
 39617
 0.18
chrX_76776329_76776480 0.08 FGF16
 fibroblast growth factor 16
 66756
 0.13
chr16_16119769_16119920 0.08 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 16131
 0.23
chr12_70132575_70133879 0.08 RAB3IP
 RAB3A interacting protein
 47
 0.95
chr16_3095827_3096553 0.08 MMP25
 matrix metallopeptidase 25
 492
 0.51
chr2_28904176_28904327 0.08 ENSG00000222232
 .
 2591
 0.25
chr20_25037809_25038550 0.08 ACSS1
 acyl-CoA synthetase short-chain family member 1
 639
 0.73
chr9_110187375_110187686 0.08 ENSG00000263459
 .
 8360
 0.24
chr3_9745623_9746706 0.08 CPNE9
 copine family member IX
 654
 0.62
chr7_5183512_5184010 0.08 ZNF890P
 zinc finger protein 890, pseudogene
 16335
 0.17
chr7_44679217_44679482 0.08 OGDH
 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
 15288
 0.18
chr15_91373266_91373417 0.08 CTD-3094K11.1
9613
 0.13
chrX_48794595_48794842 0.08 PIM2
 pim-2 oncogene
 18417
 0.08
chr20_35463892_35464165 0.08 SOGA1
 suppressor of glucose, autophagy associated 1
 19344
 0.15
chr13_20175736_20176974 0.08 MPHOSPH8
 M-phase phosphoprotein 8
 31433
 0.18
chr11_35325325_35325476 0.08 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
 2325
 0.31
chr2_43452698_43453520 0.08 ZFP36L2
 ZFP36 ring finger protein-like 2
 639
 0.76
chr4_103421804_103422645 0.08 AF213884.2
252
 0.5

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0052167 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.0 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.0 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.0 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation