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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for RFX7_RFX4_RFX1

Z-value: 1.89

Motif logo

Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol	Gene ID	Gene Info
RFX7 Ensembl NCBI GeneCards UniProt	ENSG00000181827.10	regulatory factor X7
RFX4 Ensembl NCBI GeneCards UniProt	ENSG00000111783.8	regulatory factor X4
RFX1 Ensembl NCBI GeneCards UniProt	ENSG00000132005.4	regulatory factor X1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_14117508_14117720	RFX1	517	0.636276	0.71	3.3e-02	Click!
chr19_14114170_14114321	RFX1	2829	0.143485	-0.61	8.3e-02	Click!
chr19_14098193_14098383	RFX1	18786	0.090256	-0.46	2.1e-01	Click!
chr19_14115805_14115956	RFX1	1194	0.304648	-0.33	3.8e-01	Click!
chr19_14097175_14097513	RFX1	19730	0.089165	0.19	6.3e-01	Click!
chr12_106976541_106976692	RFX4	69	0.983917	-0.69	3.8e-02	Click!
chr12_106976708_106976895	RFX4	116	0.978928	-0.58	1.0e-01	Click!
chr12_106977103_106977347	RFX4	198	0.964547	-0.53	1.4e-01	Click!
chr12_106977353_106977687	RFX4	97	0.981217	-0.47	2.0e-01	Click!
chr12_107038841_107038992	RFX4	744	0.722339	0.08	8.3e-01	Click!
chr15_56497240_56497432	RFX7	15252	0.222248	-0.69	3.9e-02	Click!
chr15_56497619_56497800	RFX7	15625	0.221027	-0.44	2.3e-01	Click!
chr15_56535646_56535941	RFX7	310	0.588635	0.44	2.4e-01	Click!
chr15_56533191_56533342	RFX7	2198	0.300470	0.29	4.6e-01	Click!
chr15_56534020_56534334	RFX7	1287	0.420687	-0.21	5.8e-01	Click!

Activity of the RFX7_RFX4_RFX1 motif across conditions

Conditions sorted by the z-value of the RFX7_RFX4_RFX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_60681680_60681991	0.71	RP11-881M11.1		311	0.57
chrX_129240382_129240549	0.71	ELF4	E74-like factor 4 (ets domain transcription factor)	3871	0.25
chr6_36930730_36930881	0.69	PI16	peptidase inhibitor 16	8596	0.17
chr5_87500281_87500432	0.67	TMEM161B	transmembrane protein 161B	16092	0.24
chr16_72127026_72127450	0.65	TXNL4B	thioredoxin-like 4B	218	0.48
chr12_68041654_68041805	0.64	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	389	0.9
chr1_114299127_114299278	0.61	PHTF1	putative homeodomain transcription factor 1	2301	0.32
chr15_74219539_74219761	0.58	LOXL1-AS1	LOXL1 antisense RNA 1	386	0.69
chr13_24007256_24007423	0.58	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	502	0.88
chr3_53286274_53286458	0.55	TKT	transketolase	3650	0.18
chr13_51210281_51210432	0.54	DLEU7-AS1	DLEU7 antisense RNA 1	171636	0.03
chr8_83009707_83009858	0.54	SNX16	sorting nexin 16	254681	0.02
chr10_104813584_104814284	0.53	NT5C2	5'-nucleotidase, cytosolic II	40191	0.17
chr22_41940614_41940785	0.53	POLR3H	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	89	0.96
chrX_69700064_69700215	0.53	DLG3-AS1	DLG3 antisense RNA 1	24295	0.14
chr19_38704733_38704884	0.51	DPF1	D4, zinc and double PHD fingers family 1	9005	0.1
chr11_113185335_113185537	0.50	TTC12	tetratricopeptide repeat domain 12	97	0.74
chr7_134468265_134468416	0.49	CALD1	caldesmon 1	3911	0.34
chr16_56553332_56553558	0.49	BBS2	Bardet-Biedl syndrome 2	508	0.72
chr12_121974248_121974441	0.49	KDM2B	lysine (K)-specific demethylase 2B	204	0.95
chr12_109490039_109490279	0.48	USP30	ubiquitin specific peptidase 30	232	0.86
chr17_9938062_9938213	0.43	GAS7	growth arrest-specific 7	1717	0.42
chr12_56415486_56415766	0.42	IKZF4	IKAROS family zinc finger 4 (Eos)	526	0.58
chr1_182808109_182808399	0.42	DHX9	DEAH (Asp-Glu-Ala-His) box helicase 9	250	0.93
chr19_19496596_19496747	0.41	GATAD2A	GATA zinc finger domain containing 2A	29	0.97
chr14_60336804_60337446	0.41	RTN1	reticulon 1	559	0.81
chr1_94557807_94557958	0.41	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	28799	0.17
chr8_59323575_59323965	0.41	UBXN2B	UBX domain protein 2B	53	0.99
chr13_45332731_45332955	0.41	ENSG00000238932	.	130034	0.05
chr8_135844464_135844657	0.40	ENSG00000199153	.	27372	0.21
chr18_67910518_67910950	0.38	RTTN	rotatin	37553	0.17
chr3_71778257_71778408	0.38	EIF4E3	eukaryotic translation initiation factor 4E family member 3	16	0.98
chr8_38215915_38216066	0.38	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	22349	0.11
chr16_284422_284736	0.37	ITFG3	integrin alpha FG-GAP repeat containing 3	34	0.95
chr3_16216188_16216711	0.37	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	233	0.95
chr7_20370368_20370519	0.36	ITGB8	integrin, beta 8	118	0.93
chr4_119755136_119755442	0.36	SEC24D	SEC24 family member D	2004	0.43
chr22_41865180_41865722	0.36	ACO2	aconitase 2, mitochondrial	317	0.72
chr18_46477183_46477549	0.36	SMAD7	SMAD family member 7	285	0.93
chr2_27851709_27851860	0.36	CCDC121	coiled-coil domain containing 121	26	0.54
chr10_3542796_3543180	0.35	RP11-184A2.3		250271	0.02
chr14_90989296_90989447	0.35	ENSG00000252748	.	42114	0.16
chr5_137474933_137475144	0.35	NME5	NME/NM23 family member 5	66	0.95
chr5_43313895_43314459	0.35	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	563	0.78
chr9_4833030_4833181	0.34	RCL1	RNA terminal phosphate cyclase-like 1	3621	0.19
chr18_44526809_44527253	0.34	KATNAL2	katanin p60 subunit A-like 2	213	0.91
chr9_117149358_117150269	0.33	AKNA	AT-hook transcription factor	430	0.85
chr4_15471443_15471718	0.33	CC2D2A	coiled-coil and C2 domain containing 2A	26	0.98
chr12_108155132_108155624	0.33	PRDM4	PR domain containing 4	441	0.8
chr1_246957975_246958211	0.33	ENSG00000227953	.	4167	0.19
chr12_117470651_117470922	0.33	TESC	tescalcin	13850	0.24
chr20_62492615_62492766	0.32	ABHD16B	abhydrolase domain containing 16B	124	0.81
chr1_51702634_51703015	0.32	RNF11	ring finger protein 11	881	0.51
chr20_7860455_7860643	0.32	HAO1	hydroxyacid oxidase (glycolate oxidase) 1	60572	0.14
chr6_144016913_144017064	0.31	PHACTR2	phosphatase and actin regulator 2	17783	0.25
chr18_19181079_19181230	0.31	ESCO1	establishment of sister chromatid cohesion N-acetyltransferase 1	457	0.78
chr15_23810880_23811333	0.31	MKRN3	makorin ring finger protein 3	186	0.93
chr8_142141364_142141568	0.31	RP11-809O17.1		1406	0.4
chr6_112823116_112823311	0.31	ENSG00000239095	.	25285	0.2
chr5_148960365_148960516	0.31	ARHGEF37	Rho guanine nucleotide exchange factor (GEF) 37	596	0.7
chr9_130478225_130478386	0.31	PTRH1	peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)	23	0.5
chr14_102771581_102771785	0.30	MOK	MOK protein kinase	146	0.95
chr12_57863878_57864029	0.30	ARHGAP9	Rho GTPase activating protein 9	4764	0.09
chr16_24550328_24550661	0.30	RBBP6	retinoblastoma binding protein 6	383	0.91
chr1_109133476_109133627	0.30	FAM102B	family with sequence similarity 102, member B	30840	0.18
chr2_47143081_47143706	0.30	TTC7A	tetratricopeptide repeat domain 7A	97	0.56
chr7_157361731_157362127	0.30	ENSG00000207960	.	5185	0.23
chr6_159065865_159066243	0.29	DYNLT1	dynein, light chain, Tctex-type 1	283	0.9
chr5_322625_322798	0.29	AHRR	aryl-hydrocarbon receptor repressor	26	0.98
chr16_46722656_46723038	0.29	VPS35	vacuolar protein sorting 35 homolog (S. cerevisiae)	257	0.79
chr1_153514824_153514975	0.29	S100A5	S100 calcium binding protein A5	658	0.47
chr11_65684234_65684385	0.29	C11orf68	chromosome 11 open reading frame 68	1522	0.19
chr18_21562271_21562511	0.29	TTC39C	tetratricopeptide repeat domain 39C	10346	0.18
chr7_139477359_139477510	0.29	HIPK2	homeodomain interacting protein kinase 2	83	0.91
chr10_31891715_31891977	0.29	ENSG00000222412	.	153218	0.04
chr1_236579767_236579918	0.29	EDARADD	EDAR-associated death domain	21126	0.21
chr11_83538868_83539293	0.29	DLG2	discs, large homolog 2 (Drosophila)	102634	0.08
chr8_89338891_89339093	0.29	RP11-586K2.1		73	0.93
chr8_132929379_132929536	0.28	EFR3A	EFR3 homolog A (S. cerevisiae)	13101	0.3
chr6_35327335_35327486	0.28	PPARD	peroxisome proliferator-activated receptor delta	17008	0.18
chr12_72663874_72664300	0.28	ENSG00000236333	.	1684	0.39
chr5_176873858_176874453	0.28	PRR7	proline rich 7 (synaptic)	327	0.6
chr6_89790525_89790732	0.28	PNRC1	proline-rich nuclear receptor coactivator 1	131	0.65
chrX_102659686_102660224	0.28	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	27846	0.15
chr13_94995296_94995447	0.28	ENSG00000212057	.	122273	0.06
chr1_40349190_40349341	0.28	TRIT1	tRNA isopentenyltransferase 1	87	0.95
chr12_117256876_117257597	0.28	ENSG00000201382	.	37326	0.16
chr3_158440703_158441168	0.28	MFSD1	major facilitator superfamily domain containing 1	9052	0.14
chr7_12726016_12726488	0.28	ARL4A	ADP-ribosylation factor-like 4A	229	0.95
chr12_7780986_7781137	0.28	APOBEC1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	37428	0.14
chr11_124543701_124544006	0.28	SIAE	sialic acid acetylesterase	76	0.54
chr16_69806984_69807135	0.27	WWP2	WW domain containing E3 ubiquitin protein ligase 2	3031	0.16
chr2_204192770_204192939	0.27	ABI2	abl-interactor 2	88	0.95
chr19_12847748_12847986	0.27	ASNA1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	86	0.91
chr10_118608958_118609220	0.27	ENO4	enolase family member 4	5	0.62
chr8_144717886_144718135	0.27	ZNF623	zinc finger protein 623	173	0.86
chr4_79565972_79566123	0.27	ENSG00000238816	.	4793	0.24
chr10_73137273_73137542	0.27	CDH23	cadherin-related 23	19284	0.2
chr16_89392673_89392885	0.27	ANKRD11	ankyrin repeat domain 11	2615	0.19
chr7_50937406_50937557	0.27	RP4-724E13.2		3037	0.35
chr8_108507718_108507960	0.27	ANGPT1	angiopoietin 1	616	0.85
chr10_3822916_3823697	0.27	KLF6	Kruppel-like factor 6	4079	0.25
chr17_25784229_25784755	0.27	KSR1	kinase suppressor of ras 1	752	0.67
chr6_88973481_88973632	0.27	CNR1	cannabinoid receptor 1 (brain)	97478	0.09
chr19_39389782_39390218	0.27	SIRT2	sirtuin 2	285	0.5
chr10_30637863_30638177	0.27	MTPAP	mitochondrial poly(A) polymerase	70	0.97
chr16_74700253_74700480	0.27	RFWD3	ring finger and WD repeat domain 3	69	0.97
chr1_15852991_15853242	0.26	DNAJC16	DnaJ (Hsp40) homolog, subfamily C, member 16	192	0.89
chr1_21672695_21672939	0.26	ECE1	endothelin converting enzyme 1	820	0.68
chr10_71950319_71950470	0.26	SAR1A	SAR1 homolog A (S. cerevisiae)	20115	0.17
chr11_118973164_118973374	0.26	DPAGT1	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	417	0.63
chr16_24740702_24740894	0.26	TNRC6A	trinucleotide repeat containing 6A	218	0.96
chr10_129775703_129776307	0.26	PTPRE	protein tyrosine phosphatase, receptor type, E	9539	0.25
chr19_41220379_41220905	0.26	ADCK4	aarF domain containing kinase 4	102	0.93
chr10_26829653_26829804	0.26	ENSG00000199733	.	31210	0.22
chr16_89990965_89991193	0.26	TUBB3	Tubulin beta-3 chain	1305	0.26
chr3_71833354_71833608	0.26	PROK2	prokineticin 2	731	0.68
chr17_45909036_45909270	0.26	LRRC46	leucine rich repeat containing 46	160	0.61
chr9_19048749_19049283	0.26	RRAGA	Ras-related GTP binding A	356	0.81
chr11_45939530_45939681	0.26	PEX16	peroxisomal biogenesis factor 16	1	0.96
chr5_32814538_32814689	0.26	AC026703.1		25668	0.21
chr17_36981736_36982002	0.26	CWC25	CWC25 spliceosome-associated protein homolog (S. cerevisiae)	135	0.6
chr12_93861082_93861233	0.26	MRPL42	mitochondrial ribosomal protein L42	107	0.96
chr4_154170450_154170719	0.25	TRIM2	tripartite motif containing 2	7978	0.19
chr6_76134945_76135096	0.25	ENSG00000263533	.	3103	0.24
chr7_100147933_100148164	0.25	AGFG2	ArfGAP with FG repeats 2	5242	0.09
chr17_643534_643685	0.25	FAM57A	family with sequence similarity 57, member A	7244	0.14
chr7_22770848_22771293	0.25	AC073072.5		3831	0.22
chr8_95270579_95270730	0.25	GEM	GTP binding protein overexpressed in skeletal muscle	2344	0.37
chr15_89348318_89348469	0.25	ACAN	aggrecan	1403	0.51
chr14_24779755_24780278	0.25	CIDEB	cell death-inducing DFFA-like effector b	585	0.27
chr1_155291426_155291577	0.25	RUSC1-AS1	RUSC1 antisense RNA 1	166	0.83
chr6_123038805_123038966	0.25	PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta	178	0.96
chr6_134274349_134274704	0.25	TBPL1	TBP-like 1	164	0.97
chr10_126433321_126433647	0.25	FAM53B	family with sequence similarity 53, member B	646	0.68
chr19_1249888_1250191	0.25	MIDN	midnolin	152	0.89
chr22_40781561_40781851	0.25	RP5-1042K10.10		2515	0.24
chr1_14928581_14928732	0.25	KAZN	kazrin, periplakin interacting protein	3443	0.4
chr7_7679470_7679820	0.25	RPA3	replication protein A3, 14kDa	12	0.99
chr22_41110494_41110716	0.25	MCHR1	melanin-concentrating hormone receptor 1	35328	0.15
chr14_37131043_37131256	0.25	PAX9	paired box 9	79	0.97
chr2_27008209_27008614	0.25	CENPA	centromere protein A	454	0.81
chr15_49158132_49158339	0.24	SHC4	SHC (Src homology 2 domain containing) family, member 4	11451	0.16
chr15_96888125_96888276	0.24	ENSG00000222651	.	11710	0.15
chr1_163038601_163039117	0.24	RGS4	regulator of G-protein signaling 4	76	0.98
chr22_41876170_41876321	0.24	ACO2	aconitase 2, mitochondrial	11111	0.14
chr6_105584147_105584651	0.24	BVES	blood vessel epicardial substance	161	0.57
chr3_55162466_55162710	0.24	LRTM1	leucine-rich repeats and transmembrane domains 1	161473	0.04
chr6_169899180_169899331	0.24	WDR27	WD repeat domain 27	161533	0.03
chr9_35730837_35731142	0.24	CREB3	cAMP responsive element binding protein 3	1343	0.19
chrX_102631036_102631748	0.24	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	57	0.97
chr5_177910677_177910900	0.24	CTB-26E19.1		40693	0.16
chr2_26624476_26625174	0.23	DRC1	dynein regulatory complex subunit 1 homolog (Chlamydomonas)	41	0.98
chr3_9321894_9322371	0.23	SRGAP3	SLIT-ROBO Rho GTPase activating protein 3	31069	0.15
chr8_145086053_145086204	0.23	SPATC1	spermatogenesis and centriole associated 1	454	0.53
chr1_111214730_111214881	0.23	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	2850	0.25
chr11_18413881_18414032	0.23	LDHA	lactate dehydrogenase A	1979	0.21
chr18_74220071_74220222	0.23	RP11-17M16.1	uncharacterized protein LOC400658	12669	0.16
chr2_136782710_136782861	0.23	AC093391.2		12750	0.23
chr16_10940554_10940705	0.23	TVP23A	trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)	27987	0.13
chr6_98174316_98174467	0.23	ENSG00000238367	.	298016	0.01
chr19_506928_507179	0.23	TPGS1	tubulin polyglutamylase complex subunit 1	246	0.76
chr4_4858411_4858646	0.23	MSX1	msh homeobox 1	2865	0.36
chr5_131761596_131761780	0.23	AC116366.5		458	0.75
chr6_135518404_135518725	0.23	MYB-AS1	MYB antisense RNA 1	1431	0.4
chr3_124839558_124839780	0.23	SLC12A8	solute carrier family 12, member 8	29	0.97
chr16_88770632_88770948	0.23	RNF166	ring finger protein 166	765	0.36
chr19_40790055_40790780	0.23	AKT2	v-akt murine thymoma viral oncogene homolog 2	312	0.78
chr7_100728744_100728929	0.22	TRIM56	tripartite motif containing 56	33	0.96
chr16_29714029_29714180	0.22	QPRT	quinolinate phosphoribosyltransferase	23601	0.09
chr3_133524288_133524537	0.22	SRPRB	signal recognition particle receptor, B subunit	47	0.98
chr2_219187541_219188186	0.22	PNKD	paroxysmal nonkinesigenic dyskinesia	33	0.95
chr17_80056446_80056770	0.22	FASN	fatty acid synthase	400	0.69
chr12_12659421_12659637	0.22	DUSP16	dual specificity phosphatase 16	14530	0.24
chr2_232505412_232505650	0.22	ENSG00000239202	.	5453	0.2
chr14_75469101_75469426	0.22	EIF2B2	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	351	0.81
chr18_43999077_43999228	0.22	RNF165	ring finger protein 165	84965	0.09
chrX_69354363_69354644	0.22	IGBP1	immunoglobulin (CD79A) binding protein 1	1190	0.39
chr5_142149418_142149898	0.22	ARHGAP26	Rho GTPase activating protein 26	291	0.94
chr1_115641933_115642500	0.22	TSPAN2	tetraspanin 2	10095	0.27
chrX_152760469_152760831	0.22	BGN	biglycan	199	0.63
chr3_98614067_98614223	0.22	DCBLD2	discoidin, CUB and LCCL domain containing 2	5870	0.19
chr7_26141005_26141262	0.22	ENSG00000266430	.	41174	0.15
chr1_117113127_117113628	0.22	CD58	CD58 molecule	271	0.9
chr16_29875041_29875192	0.22	CDIPT-AS1	CDIPT antisense RNA 1 (head to head)	39	0.5
chr11_118963829_118963980	0.22	H2AFX	H2A histone family, member X	2273	0.12
chr1_161014942_161015228	0.22	USF1	upstream transcription factor 1	354	0.74
chrX_77041755_77041987	0.22	ATRX	alpha thalassemia/mental retardation syndrome X-linked	169	0.96
chr13_98905513_98905664	0.22	RP11-573N10.1		19684	0.17
chr17_55951944_55952245	0.22	CUEDC1	CUE domain containing 1	2063	0.3
chr9_79009543_79009829	0.22	RFK	riboflavin kinase	265	0.94
chr1_27445743_27446018	0.22	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	35093	0.15
chr5_95998257_95998589	0.21	CAST	calpastatin	244	0.93
chr11_65267780_65268262	0.21	SCYL1	SCY1-like 1 (S. cerevisiae)	24527	0.09
chr20_56280672_56280842	0.21	PMEPA1	prostate transmembrane protein, androgen induced 1	4059	0.31
chr1_28563015_28563254	0.21	ATPIF1	ATPase inhibitory factor 1	469	0.68
chr9_34620609_34620827	0.21	DCTN3	dynactin 3 (p22)	203	0.86
chr2_170361254_170361475	0.21	KLHL41	kelch-like family member 41	4848	0.2
chr14_96857563_96858081	0.21	AK7	adenylate kinase 7	626	0.65
chr19_58951512_58951663	0.21	ZNF132	zinc finger protein 132	2	0.94

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.4	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.4	GO:1902019	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1	0.5	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	0.6	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.1	0.2	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.3	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.3	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.1	0.2	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.3	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	0.5	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1	0.2	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.1	0.2	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.7	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0016559	peroxisome fission(GO:0016559)
0.1	0.2	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.1	0.2	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.1	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0009208	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1	0.2	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.3	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.5	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.0	0.6	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.2	GO:0017085	response to insecticide(GO:0017085)
0.0	0.4	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.4	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.2	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.2	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.2	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.1	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.4	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.2	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.2	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.2	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.2	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0032402	melanosome transport(GO:0032402)
0.0	0.3	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.2	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.3	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0051593	response to folic acid(GO:0051593)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0006949	syncytium formation(GO:0006949)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.1	GO:0090267	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.0	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.0	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.0	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.0	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.2	GO:0070192	synapsis(GO:0007129) chromosome organization involved in meiotic cell cycle(GO:0070192)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0051957	positive regulation of glutamate secretion(GO:0014049) positive regulation of amino acid transport(GO:0051957)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.3	GO:0035195	gene silencing by miRNA(GO:0035195)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:0031670	cellular response to nutrient(GO:0031670)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:1901890	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.6	GO:0031124	mRNA 3'-end processing(GO:0031124)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.0	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.4	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.0	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.0	0.5	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.0	GO:0051299	centrosome separation(GO:0051299)
0.0	0.3	GO:0016236	macroautophagy(GO:0016236)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.0	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.7	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	0.0	GO:0030852	regulation of granulocyte differentiation(GO:0030852)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.3	GO:0051225	spindle assembly(GO:0051225)
0.0	0.3	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.2	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0031297	replication fork processing(GO:0031297)
0.0	0.3	GO:0032608	interferon-beta production(GO:0032608)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.0	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.0	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.0	GO:0006101	citrate metabolic process(GO:0006101)
0.0	0.1	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:1902750	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	1.0	GO:0051028	mRNA transport(GO:0051028)
0.0	0.0	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.9	GO:0008033	tRNA processing(GO:0008033)
0.0	0.2	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.0	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0045844	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:0015825	L-serine transport(GO:0015825) serine transport(GO:0032329)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:1901998	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0031958	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.0	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.0	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0010824	regulation of centrosome duplication(GO:0010824)
0.0	0.1	GO:0030261	chromosome condensation(GO:0030261)
0.0	0.0	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.0	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.0	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.2	GO:0007632	visual behavior(GO:0007632)
0.0	0.0	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.0	0.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.1	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.1	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.1	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.3	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070852	cell body fiber(GO:0070852)
0.1	0.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.5	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.7	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.3	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.2	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.4	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.5	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.3	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.4	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.3	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.3	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.4	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.0	GO:0038201	TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.8	GO:0016605	PML body(GO:0016605)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.3	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.4	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.0	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.9	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.3	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.6	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.2	GO:0001533	cornified envelope(GO:0001533)
0.0	0.5	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.2	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.9	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.0	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.3	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.7	GO:0070628	proteasome binding(GO:0070628)
0.1	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.2	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.4	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.4	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.2	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.8	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.2	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.6	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.3	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.2	GO:0071617	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.2	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0051192	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0008443	phosphofructokinase activity(GO:0008443)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.6	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.6	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.9	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0046977	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.0	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.5	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.2	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.3	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.0	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.4	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0	0.0	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.4	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0005507	copper ion binding(GO:0005507)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.3	PID P53 REGULATION PATHWAY	p53 pathway
0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.5	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
1.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.3	PID AURORA A PATHWAY	Aurora A signaling
0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	ST GAQ PATHWAY	G alpha q Pathway
0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.3	PID AURORA B PATHWAY	Aurora B signaling
0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	0.1	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.0	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.7	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.4	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.3	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.0	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	1.4	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC

Results for RFX7_RFX4_RFX1

Z-value: 1.89

Motif logo

Transcription factors associated with RFX7_RFX4_RFX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the RFX7_RFX4_RFX1 motif across conditions

Conditions sorted by the z-value of the RFX7_RFX4_RFX1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: