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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for RORA

Z-value: 0.71

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Transcription factors associated with RORA

Gene Symbol	Gene ID	Gene Info
RORA Ensembl NCBI GeneCards UniProt	ENSG00000069667.11	RORA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
RORA	chr15_61611314_61611465	89871	0.090299	0.72	2.8e-02	Click!
RORA	chr15_61521269_61521446	161	0.963755	0.52	1.5e-01	Click!
RORA	chr15_60878348_60878499	6317	0.239541	-0.48	1.9e-01	Click!
RORA	chr15_60897779_60897930	12529	0.226573	0.48	1.9e-01	Click!
RORA	chr15_60881361_60881613	3253	0.291829	-0.47	2.1e-01	Click!

Activity of the RORA motif across conditions

Conditions sorted by the z-value of the RORA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_6567467_6567618	0.28	ENSG00000252110	.	1117	0.53
chr3_184037306_184037783	0.26	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	1	0.95
chr11_132813237_132813595	0.25	OPCML	opioid binding protein/cell adhesion molecule-like	150	0.98
chr16_49677980_49678248	0.24	ZNF423	zinc finger protein 423	3351	0.32
chrX_102940107_102940387	0.23	MORF4L2	mortality factor 4 like 2	902	0.43
chr1_223302857_223303051	0.23	TLR5	toll-like receptor 5	5144	0.33
chr5_39423074_39423254	0.22	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	1806	0.48
chr8_50968595_50968898	0.21	SNTG1	syntrophin, gamma 1	144041	0.05
chr4_89976890_89977204	0.21	FAM13A	family with sequence similarity 13, member A	1264	0.56
chr12_50611414_50611565	0.21	RP3-405J10.4		1898	0.22
chr7_101525780_101526170	0.21	CTA-339C12.1		57966	0.12
chr2_243030793_243031816	0.20	AC093642.5		460	0.62
chr4_176568169_176568320	0.20	GPM6A	glycoprotein M6A	140294	0.05
chr4_183047320_183047598	0.20	AC108142.1		17470	0.17
chr2_41837870_41838465	0.19	ENSG00000221372	.	14641	0.29
chr13_40976108_40976619	0.19	ENSG00000252812	.	5214	0.32
chr13_24006860_24007105	0.19	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	859	0.74
chr17_3379575_3379800	0.19	ASPA	aspartoacylase	391	0.8
chr7_92242274_92242425	0.19	FAM133B	family with sequence similarity 133, member B	22641	0.2
chr17_65525390_65525554	0.19	CTD-2653B5.1		4875	0.23
chr17_39265148_39265305	0.19	KRTAP4-9	keratin associated protein 4-9	3642	0.08
chr3_20616495_20616647	0.19	ENSG00000206807	.	67323	0.14
chr6_27205685_27206711	0.18	PRSS16	protease, serine, 16 (thymus)	9282	0.19
chr2_145218006_145218157	0.18	ZEB2	zinc finger E-box binding homeobox 2	29944	0.22
chr6_76147146_76147428	0.18	ENSG00000263533	.	9164	0.18
chr1_245316415_245317636	0.18	KIF26B	kinesin family member 26B	1262	0.47
chr1_23610259_23610426	0.18	HNRNPR	heterogeneous nuclear ribonucleoprotein R	60413	0.09
chr12_77748772_77748964	0.17	ENSG00000238769	.	192063	0.03
chr10_25007047_25007198	0.17	ARHGAP21	Rho GTPase activating protein 21	3673	0.34
chr16_2517636_2518674	0.17	RP11-715J22.2		59	0.92
chr3_183005602_183005777	0.17	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	22557	0.18
chrX_100334578_100334939	0.17	TMEM35	transmembrane protein 35	1049	0.47
chr6_86113632_86113933	0.17	NT5E	5'-nucleotidase, ecto (CD73)	46027	0.19
chr4_77483255_77483500	0.17	ENSG00000263445	.	11344	0.16
chr7_101579659_101580126	0.17	CTB-181H17.1		23504	0.22
chr8_27492286_27492503	0.17	SCARA3	scavenger receptor class A, member 3	696	0.66
chr16_86700893_86701044	0.17	FOXL1	forkhead box L1	88853	0.08
chr1_101359369_101359680	0.17	EXTL2	exostosin-like glycosyltransferase 2	696	0.48
chr1_96354702_96354941	0.16	ENSG00000221798	.	2725	0.41
chr7_4722786_4723588	0.16	FOXK1	forkhead box K1	1247	0.49
chr14_93701571_93701751	0.16	UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	16634	0.14
chrX_11456012_11456286	0.16	ARHGAP6	Rho GTPase activating protein 6	10256	0.3
chr3_114161410_114161561	0.16	ZBTB20	zinc finger and BTB domain containing 20	12045	0.25
chr8_71580499_71580692	0.16	LACTB2	lactamase, beta 2	797	0.44
chr2_190477763_190477914	0.16	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	29354	0.16
chr16_65151579_65151789	0.16	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	4149	0.39
chr8_122651204_122651355	0.16	HAS2-AS1	HAS2 antisense RNA 1	254	0.93
chr17_45302890_45303160	0.16	ENSG00000252088	.	5017	0.14
chr12_83211442_83211593	0.16	TMTC2	transmembrane and tetratricopeptide repeat containing 2	59183	0.17
chr7_115116914_115117103	0.16	ENSG00000202377	.	104488	0.08
chr11_62162542_62162710	0.16	CTD-2531D15.5		1782	0.23
chr6_140029993_140030144	0.15	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	334311	0.01
chr1_90464057_90464208	0.15	ZNF326	zinc finger protein 326	3405	0.29
chr6_116571521_116571672	0.15	TSPYL4	TSPY-like 4	3665	0.18
chr22_46423027_46423794	0.15	RP6-109B7.5		25563	0.09
chr3_143363258_143363409	0.15	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	203967	0.03
chr3_189306684_189306989	0.15	TP63	tumor protein p63	42380	0.21
chrX_51636554_51637686	0.15	MAGED1	melanoma antigen family D, 1	385	0.89
chr1_78806002_78806206	0.15	ENSG00000212308	.	34849	0.18
chr2_46173551_46173702	0.15	PRKCE	protein kinase C, epsilon	54415	0.16
chr1_244836322_244836473	0.15	DESI2	desumoylating isopeptidase 2	19344	0.23
chr6_84139999_84140706	0.15	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	412	0.89
chr14_104023687_104023838	0.15	RP11-894P9.2		4004	0.09
chr5_36302348_36302599	0.15	RANBP3L	RAN binding protein 3-like	257	0.94
chrX_3263158_3263429	0.15	MXRA5	matrix-remodelling associated 5	1389	0.55
chr2_197957408_197957559	0.15	ANKRD44	ankyrin repeat domain 44	18085	0.25
chr2_237444042_237444193	0.15	IQCA1	IQ motif containing with AAA domain 1	27932	0.2
chr6_143508899_143509050	0.14	AIG1	androgen-induced 1	61587	0.13
chr7_95545859_95546042	0.14	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	112354	0.07
chr2_66672542_66672972	0.14	MEIS1	Meis homeobox 1	2660	0.22
chr21_33516188_33516339	0.14	ENSG00000264055	.	7954	0.26
chr17_4981225_4982338	0.14	ZFP3	ZFP3 zinc finger protein	238	0.6
chr6_80520238_80520389	0.14	ENSG00000221470	.	16289	0.28
chr2_190272487_190272871	0.14	WDR75	WD repeat domain 75	33480	0.21
chr19_57067071_57067222	0.14	AC007228.11		11634	0.12
chr8_57594130_57594603	0.14	RP11-17A4.2		192709	0.03
chr17_29543083_29543234	0.14	NF1	neurofibromin 1	15604	0.18
chr10_54074428_54074776	0.14	DKK1	dickkopf WNT signaling pathway inhibitor 1	546	0.57
chr17_67651034_67651185	0.14	MAP2K6	mitogen-activated protein kinase kinase 6	152539	0.04
chr19_34359259_34359976	0.14	ENSG00000240626	.	58913	0.13
chr3_149271657_149271885	0.14	WWTR1	WW domain containing transcription regulator 1	22268	0.17
chr20_53092813_53093232	0.14	DOK5	docking protein 5	765	0.8
chr13_20175736_20176974	0.14	MPHOSPH8	M-phase phosphoprotein 8	31433	0.18
chr16_25022284_25022579	0.14	ARHGAP17	Rho GTPase activating protein 17	4221	0.31
chr5_87436294_87437103	0.14	TMEM161B	transmembrane protein 161B	79750	0.11
chr2_101435204_101435829	0.14	NPAS2	neuronal PAS domain protein 2	1098	0.54
chr5_112417183_112417334	0.14	DCP2	decapping mRNA 2	104779	0.06
chr6_148685677_148685874	0.14	SASH1	SAM and SH3 domain containing 1	22046	0.24
chr10_29935760_29936003	0.14	SVIL	supervillin	11980	0.21
chr4_81192880_81193031	0.14	FGF5	fibroblast growth factor 5	5162	0.27
chr10_62588054_62588205	0.14	CDK1	cyclin-dependent kinase 1	48218	0.16
chr11_65199714_65199921	0.14	ENSG00000245532	.	12112	0.11
chr15_74232964_74233156	0.14	LOXL1-AS1	LOXL1 antisense RNA 1	12471	0.14
chr9_135895662_135895884	0.14	GTF3C5	general transcription factor IIIC, polypeptide 5, 63kDa	10303	0.13
chr5_142005239_142005585	0.14	FGF1	fibroblast growth factor 1 (acidic)	4505	0.24
chr6_56239918_56240091	0.14	COL21A1	collagen, type XXI, alpha 1	18888	0.21
chr11_19736431_19736825	0.14	NAV2	neuron navigator 2	1485	0.49
chr17_2394357_2394508	0.13	METTL16	methyltransferase like 16	20748	0.15
chr18_72843553_72843775	0.13	ZADH2	zinc binding alcohol dehydrogenase domain containing 2	73804	0.12
chr8_136478593_136478847	0.13	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	7770	0.25
chr4_37668617_37668785	0.13	RELL1	RELT-like 1	1698	0.42
chr9_118378371_118378558	0.13	DEC1	deleted in esophageal cancer 1	474367	0.01
chr11_100800789_100801024	0.13	ENSG00000238388	.	4099	0.25
chr9_678099_678250	0.13	RP11-130C19.3		546	0.81
chr6_24743331_24743534	0.13	C6orf62	chromosome 6 open reading frame 62	22368	0.12
chr3_72445670_72445821	0.13	RYBP	RING1 and YY1 binding protein	50324	0.17
chr3_99591567_99591782	0.13	FILIP1L	filamin A interacting protein 1-like	3274	0.32
chr18_479598_479768	0.13	COLEC12	collectin sub-family member 12	21039	0.18
chr10_17275327_17275794	0.13	RP11-124N14.3		1272	0.37
chr7_98248959_98249425	0.13	NPTX2	neuronal pentraxin II	2583	0.39
chr8_29133372_29133712	0.13	ENSG00000212034	.	5964	0.17
chr1_203503529_203503721	0.13	OPTC	opticin	38527	0.16
chr11_132831774_132832000	0.13	OPCML	opioid binding protein/cell adhesion molecule-like	18224	0.28
chr1_161992740_161992891	0.13	OLFML2B	olfactomedin-like 2B	615	0.79
chr3_187989024_187989175	0.12	LPP	LIM domain containing preferred translocation partner in lipoma	31447	0.22
chr5_88178054_88178448	0.12	MEF2C	myocyte enhancer factor 2C	713	0.52
chr1_219116097_219116279	0.12	LYPLAL1	lysophospholipase-like 1	230998	0.02
chr18_7568558_7569022	0.12	PTPRM	protein tyrosine phosphatase, receptor type, M	973	0.7
chr8_8153665_8153908	0.12	ALG1L13P	asparagine-linked glycosylation 1-like 13, pseudogene	54853	0.11
chr10_4283577_4283877	0.12	ENSG00000207124	.	273417	0.02
chr9_693371_693572	0.12	RP11-130C19.3		7916	0.22
chr16_70749819_70749970	0.12	VAC14	Vac14 homolog (S. cerevisiae)	15746	0.13
chr3_157078098_157078249	0.12	ENSG00000243176	.	74224	0.1
chr5_67825283_67825434	0.12	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	236962	0.02
chr1_41176173_41176466	0.12	NFYC	nuclear transcription factor Y, gamma	1104	0.44
chr6_89692667_89692818	0.12	AL079342.1	Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741	18496	0.18
chr7_27217405_27217623	0.12	RP1-170O19.20	Uncharacterized protein	2118	0.1
chr13_113841496_113841673	0.12	PCID2	PCI domain containing 2	20836	0.11
chr18_77746974_77747125	0.12	TXNL4A	thioredoxin-like 4A	1488	0.39
chr2_236401822_236402641	0.12	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	502	0.83
chr4_147568677_147568828	0.12	ENSG00000264323	.	8339	0.22
chr15_99440572_99440803	0.12	RP11-654A16.1		3923	0.25
chr12_56241387_56241673	0.12	MMP19	matrix metallopeptidase 19	4796	0.11
chr10_116527243_116527917	0.12	FAM160B1	family with sequence similarity 160, member B1	53923	0.15
chr4_41215270_41215769	0.12	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	956	0.59
chr3_89153572_89153739	0.12	EPHA3	EPH receptor A3	3019	0.42
chr1_205326238_205326434	0.12	KLHDC8A	kelch domain containing 8A	118	0.96
chr6_167764253_167765165	0.12	TTLL2	tubulin tyrosine ligase-like family, member 2	26135	0.18
chr13_76026824_76027007	0.12	TBC1D4	TBC1 domain family, member 4	29335	0.19
chr11_7715663_7715870	0.12	RP11-35J10.4		11069	0.15
chr14_55119300_55119828	0.12	SAMD4A	sterile alpha motif domain containing 4A	84927	0.09
chr14_42072367_42072518	0.12	LRFN5	leucine rich repeat and fibronectin type III domain containing 5	4331	0.28
chr8_123867992_123868238	0.12	ZHX2	zinc fingers and homeoboxes 2	7509	0.2
chr12_10868992_10869331	0.12	YBX3	Y box binding protein 3	6745	0.18
chr6_53928343_53928541	0.12	MLIP-AS1	MLIP antisense RNA 1	16050	0.2
chr6_116726836_116726987	0.12	DSE	dermatan sulfate epimerase	34801	0.12
chr8_19148668_19149118	0.12	SH2D4A	SH2 domain containing 4A	22235	0.28
chr3_73505367_73505518	0.12	PDZRN3	PDZ domain containing ring finger 3	18341	0.27
chr1_234630809_234631231	0.11	TARBP1	TAR (HIV-1) RNA binding protein 1	16171	0.21
chr1_31883502_31883784	0.11	SERINC2	serine incorporator 2	595	0.71
chr2_45004607_45004758	0.11	ENSG00000252896	.	4587	0.34
chr15_100583304_100583570	0.11	ENSG00000252957	.	30958	0.16
chr7_130595711_130595921	0.11	ENSG00000226380	.	33518	0.2
chrX_135267737_135267902	0.11	FHL1	four and a half LIM domains 1	11094	0.22
chr3_66101350_66101501	0.11	SLC25A26	solute carrier family 25 (S-adenosylmethionine carrier), member 26	17860	0.25
chr3_37352486_37352637	0.11	GOLGA4	golgin A4	28887	0.15
chr2_143919802_143919953	0.11	RP11-190J23.1		9864	0.26
chr3_21686525_21686676	0.11	ZNF385D-AS1	ZNF385D antisense RNA 1	102292	0.08
chr2_216298275_216298426	0.11	FN1	fibronectin 1	2440	0.3
chr1_150480597_150480804	0.11	ECM1	extracellular matrix protein 1	117	0.94
chr19_55996251_55997143	0.11	NAT14	N-acetyltransferase 14 (GCN5-related, putative)	96	0.92
chr9_21558481_21558945	0.11	MIR31HG	MIR31 host gene (non-protein coding)	955	0.56
chr18_40710046_40710304	0.11	RIT2	Ras-like without CAAX 2	14518	0.31
chr2_227658957_227659437	0.11	IRS1	insulin receptor substrate 1	5278	0.23
chr11_102340087_102340238	0.11	RP11-315O6.2	HCG1815860; Uncharacterized protein	2176	0.27
chr4_169615079_169615336	0.11	ENSG00000206613	.	7340	0.22
chr6_170053828_170054109	0.11	WDR27	WD repeat domain 27	6820	0.18
chr10_15476627_15476827	0.11	FAM171A1	family with sequence similarity 171, member A1	63666	0.14
chr3_124420440_124420591	0.11	ENSG00000263775	.	4632	0.17
chr2_20795534_20795685	0.11	HS1BP3-IT1	HS1BP3 intronic transcript 1 (non-protein coding)	3301	0.28
chr11_26353711_26353957	0.11	ANO3	anoctamin 3	166	0.98
chr8_20186622_20186773	0.11	LZTS1	leucine zipper, putative tumor suppressor 1	25223	0.2
chr5_102862275_102862460	0.11	NUDT12	nudix (nucleoside diphosphate linked moiety X)-type motif 12	36123	0.24
chr15_83501556_83501772	0.11	HOMER2	homer homolog 2 (Drosophila)	16815	0.13
chr3_156409051_156409287	0.11	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	10214	0.23
chr11_121835249_121835400	0.11	ENSG00000252556	.	39739	0.19
chrX_120775735_120775886	0.11	ENSG00000221217	.	226910	0.02
chr1_160311738_160311889	0.11	COPA	coatomer protein complex, subunit alpha	1225	0.26
chr3_54462200_54462389	0.11	ESRG	embryonic stem cell related (non-protein coding)	211590	0.02
chr7_94029074_94029225	0.11	COL1A2	collagen, type I, alpha 2	5276	0.3
chr21_16663113_16663407	0.11	NRIP1	nuclear receptor interacting protein 1	225939	0.02
chr6_116382044_116382245	0.11	FRK	fyn-related kinase	223	0.94
chr2_7663684_7663835	0.11	ENSG00000221255	.	53213	0.19
chr2_190017431_190017582	0.11	ENSG00000264725	.	19669	0.19
chr6_24901738_24901889	0.11	FAM65B	family with sequence similarity 65, member B	9382	0.22
chrX_99899594_99899808	0.11	SRPX2	sushi-repeat containing protein, X-linked 2	486	0.79
chr4_145568031_145568374	0.11	HHIP	hedgehog interacting protein	878	0.49
chr17_13265618_13265967	0.11	ENSG00000266115	.	137853	0.05
chr6_27462859_27463076	0.11	ZNF184	zinc finger protein 184	22070	0.21
chr4_157872609_157873145	0.11	PDGFC	platelet derived growth factor C	19178	0.21
chr10_14920855_14921866	0.11	SUV39H2	suppressor of variegation 3-9 homolog 2 (Drosophila)	439	0.82
chr13_60709592_60709946	0.11	DIAPH3-AS2	DIAPH3 antisense RNA 2	9063	0.22
chr6_139691315_139691533	0.11	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	3926	0.31
chr5_103849207_103849358	0.11	ENSG00000239808	.	252755	0.02
chrX_100545955_100546357	0.10	TAF7L	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa	168	0.93
chr9_128000677_128001068	0.10	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2737	0.2
chr7_32627060_32627248	0.10	AVL9	AVL9 homolog (S. cerevisiase)	44287	0.18
chr8_106487505_106487656	0.10	ZFPM2	zinc finger protein, FOG family member 2	53532	0.18
chr4_88786510_88786661	0.10	MEPE	matrix extracellular phosphoglycoprotein	32446	0.16
chr6_27516181_27516437	0.10	ENSG00000206671	.	47882	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of RORA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0021508	floor plate formation(GO:0021508)
0.0	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0052308	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.3	GO:0008038	neuron recognition(GO:0008038)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0009650	UV protection(GO:0009650)
0.0	0.0	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions