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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for RORC

Z-value: 0.82

Motif logo

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Transcription factors associated with RORC

Gene Symbol Gene ID Gene Info
RORC
ENSG00000143365.12 RORC

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
RORCchr1_151796458_15179660920340.141495-0.845.0e-03Click!
RORCchr1_151797825_1517979766670.457926-0.665.3e-02Click!
RORCchr1_151798177_1517983812880.776551-0.636.7e-02Click!
RORCchr1_151795357_15179550831350.102930-0.637.1e-02Click!
RORCchr1_151796793_15179694416990.167965-0.551.2e-01Click!

Activity of the RORC motif across conditions

Conditions sorted by the z-value of the RORC motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_55996251_55997143 0.54 NAT14
 N-acetyltransferase 14 (GCN5-related, putative)
 96
 0.92
chr4_71570546_71572213 0.45 RUFY3
 RUN and FYVE domain containing 3
 861
 0.36
chr15_72529055_72529849 0.39 PKM
 pyruvate kinase, muscle
 5288
 0.17
chr15_31507532_31508310 0.34 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
 54445
 0.15
chr12_81258392_81258564 0.33 LIN7A
 lin-7 homolog A (C. elegans)
 24649
 0.18
chr10_30092462_30092778 0.32 SVIL
 supervillin
 67887
 0.12
chr8_128957071_128957260 0.30 TMEM75
 transmembrane protein 75
 3426
 0.25
chr9_94180104_94180255 0.30 NFIL3
 nuclear factor, interleukin 3 regulated
 5965
 0.3
chr10_3929254_3929732 0.29 KLF6
 Kruppel-like factor 6
 102020
 0.08
chr7_29603979_29604650 0.29 PRR15
 proline rich 15
 752
 0.51
chr9_89952337_89952906 0.29 ENSG00000212421
 .
 77256
 0.11
chr5_78985270_78986298 0.28 CMYA5
 cardiomyopathy associated 5
 84
 0.98
chr10_25007047_25007198 0.28 ARHGAP21
 Rho GTPase activating protein 21
 3673
 0.34
chr16_82693769_82693931 0.27 CDH13
 cadherin 13
 33152
 0.22
chr16_87490664_87491008 0.26 ZCCHC14
 zinc finger, CCHC domain containing 14
 24096
 0.15
chr5_39519910_39520061 0.25 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 57583
 0.16
chr4_104013838_104013994 0.25 BDH2
 3-hydroxybutyrate dehydrogenase, type 2
 7070
 0.22
chr6_80520238_80520389 0.24 ENSG00000221470
 .
 16289
 0.28
chr10_104530389_104530540 0.24 WBP1L
 WW domain binding protein 1-like
 5542
 0.16
chr11_116848096_116848381 0.24 SIK3
 SIK family kinase 3
 20478
 0.15
chr1_215256963_215257162 0.24 KCNK2
 potassium channel, subfamily K, member 2
 202
 0.97
chr15_89662933_89663145 0.23 ENSG00000239151
 .
 971
 0.55
chr17_42187560_42187844 0.23 HDAC5
 histone deacetylase 5
 1007
 0.34
chr2_28565345_28565858 0.23 AC093690.1
32275
 0.15
chr1_7812599_7812750 0.23 CAMTA1
 calmodulin binding transcription activator 1
 7653
 0.17
chr2_63971408_63971559 0.23 ENSG00000221085
 .
 48814
 0.16
chr16_80965917_80966531 0.23 CMC2
 C-x(9)-C motif containing 2
 66040
 0.09
chr13_60709592_60709946 0.22 DIAPH3-AS2
 DIAPH3 antisense RNA 2
 9063
 0.22
chr20_10536492_10536643 0.22 JAG1
 jagged 1
 106587
 0.06
chr12_6887362_6887730 0.22 ENSG00000244532
 .
 5781
 0.08
chr10_33274501_33274785 0.22 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 6748
 0.27
chr10_17391082_17391289 0.22 ST8SIA6
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
 22077
 0.18
chr12_7037386_7038830 0.22 ATN1
 atrophin 1
 632
 0.41
chr7_130589596_130590032 0.22 ENSG00000226380
 .
 27516
 0.22
chr5_64310480_64310631 0.22 ENSG00000207439
 .
 108641
 0.07
chr11_92117878_92118174 0.22 RP11-675M1.2
23316
 0.23
chr2_200319164_200319358 0.21 SATB2
 SATB homeobox 2
 1550
 0.44
chr4_46958424_46958575 0.21 GABRB1
 gamma-aminobutyric acid (GABA) A receptor, beta 1
 37241
 0.16
chr8_138161471_138161805 0.21 ENSG00000206678
 .
 44043
 0.22
chr5_160265170_160265321 0.21 ATP10B
 ATPase, class V, type 10B
 13974
 0.28
chr12_14989521_14989754 0.21 RP11-233G1.4
4389
 0.13
chr2_144709819_144710095 0.21 AC016910.1
15317
 0.26
chr9_110250307_110251795 0.20 KLF4
 Kruppel-like factor 4 (gut)
 360
 0.89
chr4_81192543_81192855 0.20 FGF5
 fibroblast growth factor 5
 4906
 0.28
chr5_66564565_66564999 0.20 CD180
 CD180 molecule
 72155
 0.13
chr2_216616741_216616892 0.20 ENSG00000212055
 .
 126826
 0.06
chr4_81206298_81206449 0.20 FGF5
 fibroblast growth factor 5
 18580
 0.23
chr11_62162542_62162710 0.20 CTD-2531D15.5
1782
 0.23
chr11_57545200_57545645 0.20 CTNND1
 catenin (cadherin-associated protein), delta 1
 3653
 0.19
chr13_37492943_37493377 0.20 SMAD9
 SMAD family member 9
 1215
 0.52
chr4_119950142_119950384 0.20 SYNPO2
 synaptopodin 2
 5637
 0.3
chr1_225837801_225838022 0.20 ENAH
 enabled homolog (Drosophila)
 2507
 0.31
chr15_91593023_91593177 0.19 AC068831.10
27248
 0.12
chr6_27647378_27647849 0.19 ENSG00000238648
 .
 48425
 0.11
chr8_124853412_124853563 0.19 FER1L6
 fer-1-like 6 (C. elegans)
 10740
 0.25
chr4_41614617_41614895 0.19 LIMCH1
 LIM and calponin homology domains 1
 30
 0.99
chr10_127104208_127104359 0.19 TEX36-AS1
 TEX36 antisense RNA 1
 158657
 0.04
chr3_150133757_150133908 0.19 TSC22D2
 TSC22 domain family, member 2
 5036
 0.31
chr9_140149846_140150685 0.19 NELFB
 negative elongation factor complex member B
 640
 0.42
chr1_29002381_29002532 0.19 GMEB1
 glucocorticoid modulatory element binding protein 1
 7164
 0.14
chr1_46378692_46378869 0.19 MAST2
 microtubule associated serine/threonine kinase 2
 480
 0.87
chr14_51862206_51862357 0.18 FRMD6
 FERM domain containing 6
 93574
 0.07
chr8_124775567_124775718 0.18 FAM91A1
 family with sequence similarity 91, member A1
 5054
 0.24
chr20_4669808_4669959 0.18 PRNP
 prion protein
 2694
 0.3
chr3_134181160_134181311 0.18 CEP63
 centrosomal protein 63kDa
 23350
 0.15
chr9_132808161_132808319 0.18 FNBP1
 formin binding protein 1
 2767
 0.27
chr12_46759532_46760006 0.17 SLC38A2
 solute carrier family 38, member 2
 679
 0.75
chr1_17867456_17867607 0.17 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 1201
 0.57
chr13_45146605_45146867 0.17 TSC22D1
 TSC22 domain family, member 1
 3656
 0.33
chr17_57451504_57451655 0.17 ENSG00000263857
 .
 8135
 0.18
chr17_62737056_62737243 0.17 RP13-104F24.1
17572
 0.18
chr7_97816035_97816206 0.17 BHLHA15
 basic helix-loop-helix family, member a15
 24619
 0.18
chr3_120215962_120216316 0.17 FSTL1
 follistatin-like 1
 46039
 0.16
chr11_71780711_71781020 0.17 NUMA1
 nuclear mitotic apparatus protein 1
 268
 0.8
chr1_61784012_61784215 0.17 NFIA
 nuclear factor I/A
 34009
 0.24
chr2_65527534_65527956 0.17 SPRED2
 sprouty-related, EVH1 domain containing 2
 34162
 0.18
chr2_20132866_20133200 0.17 WDR35
 WD repeat domain 35
 20599
 0.18
chr2_239895284_239895449 0.17 ENSG00000211566
 .
 660
 0.69
chr8_38732199_38732350 0.17 PLEKHA2
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
 26479
 0.14
chr13_38171648_38172094 0.17 POSTN
 periostin, osteoblast specific factor
 992
 0.71
chr4_100007531_100007682 0.16 ADH5
 alcohol dehydrogenase 5 (class III), chi polypeptide
 1239
 0.4
chrX_107683395_107684019 0.16 COL4A5
 collagen, type IV, alpha 5
 595
 0.63
chr3_184037306_184037783 0.16 EIF4G1
 eukaryotic translation initiation factor 4 gamma, 1
 1
 0.95
chr17_77019963_77021139 0.16 C1QTNF1
 C1q and tumor necrosis factor related protein 1
 208
 0.91
chr9_89874705_89874865 0.16 ENSG00000212421
 .
 580
 0.85
chr19_6738037_6738395 0.16 TRIP10
 thyroid hormone receptor interactor 10
 280
 0.7
chr12_129339372_129339523 0.16 GLT1D1
 glycosyltransferase 1 domain containing 1
 1366
 0.53
chr1_150135684_150135897 0.16 PLEKHO1
 pleckstrin homology domain containing, family O member 1
 6667
 0.15
chr15_73894901_73895100 0.16 NPTN
 neuroplastin
 30104
 0.2
chr20_10521227_10521501 0.16 SLX4IP
 SLX4 interacting protein
 105413
 0.06
chr11_31006065_31006277 0.16 DCDC1
 doublecortin domain containing 1
 8062
 0.32
chr2_190017431_190017582 0.16 ENSG00000264725
 .
 19669
 0.19
chr11_126799438_126799589 0.15 KIRREL3-AS2
 KIRREL3 antisense RNA 2
 11129
 0.21
chr17_70512891_70513125 0.15 ENSG00000200783
 .
 147283
 0.04
chr12_1153810_1153961 0.15 ERC1
 ELKS/RAB6-interacting/CAST family member 1
 16947
 0.19
chr2_205707475_205707729 0.15 PARD3B
 par-3 family cell polarity regulator beta
 296879
 0.01
chr19_55627735_55628805 0.15 PPP1R12C
 protein phosphatase 1, regulatory subunit 12C
 511
 0.63
chr8_12809514_12810001 0.15 KIAA1456
 KIAA1456
 226
 0.95
chr8_80343054_80343205 0.15 STMN2
 stathmin-like 2
 179920
 0.03
chr3_122201810_122202029 0.15 KPNA1
 karyopherin alpha 1 (importin alpha 5)
 31470
 0.14
chr19_7182944_7183430 0.15 INSR
 insulin receptor
 15198
 0.17
chr18_47017567_47018883 0.15 RPL17
 ribosomal protein L17
 15
 0.51
chr6_138421277_138421428 0.15 PERP
 PERP, TP53 apoptosis effector
 7296
 0.27
chr9_79792511_79793707 0.15 VPS13A-AS1
 VPS13A antisense RNA 1
 199
 0.85
chr11_104763853_104764004 0.15 CASP12
 caspase 12 (gene/pseudogene)
 5213
 0.23
chr16_65151579_65151789 0.14 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 4149
 0.39
chrX_96294671_96294822 0.14 RPA4
 replication protein A4, 30kDa
 155839
 0.04
chr17_4090765_4090916 0.14 ANKFY1
 ankyrin repeat and FYVE domain containing 1
 436
 0.68
chr9_13001851_13002398 0.14 ENSG00000222658
 .
 116804
 0.06
chr1_88292572_88292723 0.14 ENSG00000199318
 .
 373591
 0.01
chr6_4282166_4282426 0.14 ENSG00000201185
 .
 145901
 0.04
chr2_239791543_239791694 0.14 TWIST2
 twist family bHLH transcription factor 2
 34945
 0.18
chr2_192127945_192128119 0.14 MYO1B
 myosin IB
 267
 0.95
chr11_129710328_129710479 0.14 TMEM45B
 transmembrane protein 45B
 9824
 0.26
chr5_15021362_15021513 0.14 ENSG00000202269
 .
 89592
 0.09
chr1_162534114_162534517 0.14 UAP1
 UDP-N-acteylglucosamine pyrophosphorylase 1
 1512
 0.34
chr16_19124934_19125453 0.14 ITPRIPL2
 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
 61
 0.97
chr15_63525932_63526083 0.14 APH1B
 APH1B gamma secretase subunit
 42210
 0.14
chr2_190150776_190150927 0.14 ENSG00000266817
 .
 25636
 0.23
chr6_63226419_63226570 0.14 ENSG00000216072
 .
 166679
 0.04
chr2_192067478_192067647 0.14 MYO1B
 myosin IB
 42349
 0.15
chr4_116227889_116228040 0.14 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
 192932
 0.03
chr16_27297585_27297841 0.14 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 17598
 0.16
chrX_9487811_9487962 0.14 TBL1X
 transducin (beta)-like 1X-linked
 15097
 0.3
chr12_131198863_131199152 0.14 RIMBP2
 RIMS binding protein 2
 1819
 0.46
chr6_117086060_117086951 0.14 FAM162B
 family with sequence similarity 162, member B
 381
 0.87
chr14_23318650_23318801 0.14 ENSG00000212335
 .
 3212
 0.11
chr12_16501800_16502026 0.14 MGST1
 microsomal glutathione S-transferase 1
 1182
 0.59
chr3_189306684_189306989 0.14 TP63
 tumor protein p63
 42380
 0.21
chr1_42115734_42115934 0.14 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 50838
 0.16
chr1_36038675_36039393 0.13 TFAP2E
 transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
 63
 0.8
chr6_20497460_20497742 0.13 ENSG00000201683
 .
 2805
 0.26
chr14_37517694_37517845 0.13 RP11-537P22.2
49999
 0.15
chr16_66638822_66640143 0.13 CMTM3
 CKLF-like MARVEL transmembrane domain containing 3
 58
 0.95
chr1_34630625_34630811 0.13 CSMD2
 CUB and Sushi multiple domains 2
 157
 0.94
chr8_107513799_107513950 0.13 OXR1
 oxidation resistance 1
 53722
 0.17
chr8_124502561_124502827 0.13 FBXO32
 F-box protein 32
 50752
 0.11
chr1_14081545_14081696 0.13 PRDM2
 PR domain containing 2, with ZNF domain
 5689
 0.27
chr22_36235496_36235773 0.13 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 631
 0.82
chr17_64187141_64188685 0.13 CEP112
 centrosomal protein 112kDa
 60
 0.98
chr3_147072396_147072661 0.13 RP11-649A16.1
15915
 0.19
chr9_14373044_14373195 0.13 RP11-120J1.1
25800
 0.22
chr15_61209604_61209837 0.13 RP11-554D20.1
152781
 0.04
chr16_83630209_83630360 0.13 ENSG00000263785
 .
 88333
 0.08
chr10_18623245_18623419 0.13 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
 6334
 0.3
chr15_70615789_70615940 0.13 ENSG00000200216
 .
 130289
 0.06
chr7_99973393_99973544 0.13 PILRA
 paired immunoglobin-like type 2 receptor alpha
 2317
 0.14
chr15_59023939_59024090 0.13 ADAM10
 ADAM metallopeptidase domain 10
 17779
 0.14
chrX_51634929_51635080 0.13 MAGED1
 melanoma antigen family D, 1
 1625
 0.44
chr11_46311932_46312209 0.13 CREB3L1
 cAMP responsive element binding protein 3-like 1
 4607
 0.2
chr14_52708086_52708298 0.13 PTGDR
 prostaglandin D2 receptor (DP)
 26239
 0.22
chr9_77724372_77724523 0.13 OSTF1
 osteoclast stimulating factor 1
 20988
 0.17
chr11_131765018_131765169 0.13 AP004372.1
1909
 0.41
chr5_131793521_131793672 0.13 ENSG00000202533
 .
 10243
 0.13
chr14_89453077_89453228 0.13 TTC8
 tetratricopeptide repeat domain 8
 145280
 0.04
chr6_53109316_53109571 0.13 ENSG00000206908
 .
 25384
 0.15
chr5_33364778_33364929 0.13 CTD-2203K17.1
75872
 0.11
chr2_101435204_101435829 0.13 NPAS2
 neuronal PAS domain protein 2
 1098
 0.54
chr9_94184418_94184834 0.13 NFIL3
 nuclear factor, interleukin 3 regulated
 1518
 0.54
chr9_97151112_97151263 0.13 HIATL1
 hippocampus abundant transcript-like 1
 14354
 0.22
chr7_27138269_27138448 0.13 HOTAIRM1
 HOXA transcript antisense RNA, myeloid-specific 1
 100
 0.91
chr20_34324359_34324606 0.13 RBM39
 RNA binding motif protein 39
 4277
 0.14
chr5_15500949_15501183 0.12 FBXL7
 F-box and leucine-rich repeat protein 7
 481
 0.89
chr2_190272487_190272871 0.12 WDR75
 WD repeat domain 75
 33480
 0.21
chr12_120671366_120671711 0.12 PXN
 paxillin
 6891
 0.13
chrY_26417655_26417806 0.12 ENSG00000242425
 .
 60348
 0.14
chrX_47004919_47005852 0.12 NDUFB11
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
 482
 0.54
chr8_56805751_56805987 0.12 RP11-318K15.2
285
 0.88
chr16_88134555_88134901 0.12 BANP
 BTG3 associated nuclear protein
 131104
 0.05
chr16_59667984_59668135 0.12 ENSG00000200062
 .
 94029
 0.09
chr18_65691781_65691932 0.12 DSEL
 dermatan sulfate epimerase-like
 507639
 0.0
chr2_24925560_24925711 0.12 ENSG00000206732
 .
 26457
 0.19
chr15_96418443_96418594 0.12 ENSG00000222076
 .
 129485
 0.06
chr6_16725171_16725625 0.12 RP1-151F17.1
35971
 0.19
chr12_116563914_116564400 0.12 ENSG00000207967
 .
 22302
 0.2
chr7_22897710_22898017 0.12 ENSG00000221740
 .
 1631
 0.44
chr9_109876837_109877058 0.12 RP11-508N12.2
11678
 0.29
chr1_214435103_214435394 0.12 SMYD2
 SET and MYND domain containing 2
 19328
 0.27
chr11_34653922_34654073 0.12 EHF
 ets homologous factor
 14
 0.99
chr1_203503529_203503721 0.12 OPTC
 opticin
 38527
 0.16
chr7_97952929_97953353 0.12 RP11-307C18.1
976
 0.55
chr1_161536147_161536341 0.12 RP11-5K23.5
9376
 0.12
chr12_7168097_7168259 0.12 C1S
 complement component 1, s subcomponent
 189
 0.9
chr5_10704875_10705026 0.12 CTD-2154B17.4
56227
 0.12
chr7_110752755_110752906 0.12 ENSG00000238922
 .
 3417
 0.32
chr8_95048500_95048770 0.12 ENSG00000263855
 .
 62553
 0.12
chr2_179314595_179315822 0.12 PRKRA
 protein kinase, interferon-inducible double stranded RNA dependent activator
 276
 0.8
chr7_52568857_52569008 0.12 ENSG00000238506
 .
 177347
 0.03
chrX_138277340_138277570 0.12 FGF13
 fibroblast growth factor 13
 8232
 0.33
chr3_191888187_191888338 0.12 FGF12-AS1
 FGF12 antisense RNA 1
 67564
 0.12
chr18_51746912_51747063 0.12 ENSG00000207233
 .
 1795
 0.36
chr6_56213688_56213839 0.12 RP3-445N2.1
16848
 0.23
chrX_71614971_71615122 0.12 ENSG00000222810
 .
 18027
 0.22
chr20_33927086_33927237 0.12 FAM83C
 family with sequence similarity 83, member C
 46957
 0.07
chr5_36723248_36723399 0.11 CTD-2353F22.1
1952
 0.47
chr20_30457693_30458808 0.11 DUSP15
 dual specificity phosphatase 15
 125
 0.67
chr3_57051305_57051541 0.11 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 40020
 0.14
chr17_1986984_1987135 0.11 RP11-667K14.5
5916
 0.11
chr7_112740362_112740513 0.11 RP11-736E3.1
281
 0.92
chr3_150755555_150755706 0.11 MED12L
 mediator complex subunit 12-like
 48551
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of RORC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0060502 epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.0 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.0 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.0 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine