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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for RREB1

Z-value: 1.02

Motif logo

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Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
RREB1
ENSG00000124782.15 ras responsive element binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_7107379_7107726RREB12780.9327220.844.6e-03Click!
chr6_7141557_7142044RREB123220.3264570.835.5e-03Click!
chr6_7129962_7130113RREB194410.223003-0.752.1e-02Click!
chr6_7116475_7116626RREB182860.235505-0.723.0e-02Click!
chr6_7086670_7087580RREB1207050.2075600.694.0e-02Click!

Activity of the RREB1 motif across conditions

Conditions sorted by the z-value of the RREB1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_45811796_45811947 0.61 TBX21
 T-box 21
 1261
 0.39
chr12_57870819_57871184 0.61 ARHGAP9
 Rho GTPase activating protein 9
 566
 0.53
chr10_6620839_6621201 0.59 PRKCQ
 protein kinase C, theta
 1181
 0.65
chr17_56405619_56405770 0.58 BZRAP1
 benzodiazepine receptor (peripheral) associated protein 1
 249
 0.73
chr19_10714199_10714545 0.56 SLC44A2
 solute carrier family 44 (choline transporter), member 2
 1186
 0.31
chr1_206732541_206732911 0.56 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 2233
 0.27
chr2_234328294_234328612 0.55 DGKD
 diacylglycerol kinase, delta 130kDa
 31653
 0.14
chr4_102267542_102267693 0.55 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
 336
 0.83
chr16_50308098_50308268 0.54 ADCY7
 adenylate cyclase 7
 119
 0.97
chrX_40014744_40014994 0.49 BCOR
 BCL6 corepressor
 8987
 0.31
chr5_126188958_126189247 0.47 MARCH3
 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
 64818
 0.12
chr13_41555398_41555618 0.47 ELF1
 E74-like factor 1 (ets domain transcription factor)
 910
 0.61
chr1_101703704_101704393 0.47 S1PR1
 sphingosine-1-phosphate receptor 1
 1604
 0.28
chr9_134143747_134144006 0.47 FAM78A
 family with sequence similarity 78, member A
 2004
 0.31
chr1_154924890_154925041 0.46 PBXIP1
 pre-B-cell leukemia homeobox interacting protein 1
 3615
 0.1
chrX_25030795_25030946 0.46 ARX
 aristaless related homeobox
 3195
 0.34
chr17_73761527_73761678 0.44 GALK1
 galactokinase 1
 190
 0.88
chrX_118108013_118108392 0.42 LONRF3
 LON peptidase N-terminal domain and ring finger 3
 379
 0.92
chr11_128596154_128596350 0.42 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 30334
 0.16
chr10_121356767_121357010 0.41 TIAL1
 TIA1 cytotoxic granule-associated RNA binding protein-like 1
 347
 0.9
chr12_56414859_56415059 0.41 IKZF4
 IKAROS family zinc finger 4 (Eos)
 95
 0.93
chr19_7410752_7411085 0.41 CTB-133G6.1
2930
 0.22
chr7_156803754_156804127 0.41 MNX1-AS1
 MNX1 antisense RNA 1 (head to head)
 441
 0.56
chr19_4069446_4069597 0.40 ZBTB7A
 zinc finger and BTB domain containing 7A
 2578
 0.17
chr8_144108277_144108585 0.40 LY6E
 lymphocyte antigen 6 complex, locus E
 8457
 0.17
chr1_25254722_25254968 0.40 RUNX3
 runt-related transcription factor 3
 767
 0.7
chrX_128915626_128915992 0.40 SASH3
 SAM and SH3 domain containing 3
 1849
 0.35
chr12_104851638_104851843 0.40 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 961
 0.68
chr8_145027093_145027557 0.40 PLEC
 plectin
 763
 0.48
chr4_38511205_38511356 0.39 RP11-617D20.1
114916
 0.06
chr14_99733165_99733625 0.39 AL109767.1
4110
 0.24
chr21_46340224_46340398 0.39 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 459
 0.52
chr17_76123581_76124282 0.39 TMC6
 transmembrane channel-like 6
 780
 0.49
chr6_2902429_2902783 0.39 SERPINB9
 serpin peptidase inhibitor, clade B (ovalbumin), member 9
 908
 0.57
chr7_130008032_130008183 0.38 CPA5
 carboxypeptidase A5
 4825
 0.15
chr10_111768599_111769139 0.38 ADD3
 adducin 3 (gamma)
 1147
 0.51
chrY_7143368_7143656 0.38 PRKY
 protein kinase, Y-linked, pseudogene
 1158
 0.57
chr20_43599328_43599508 0.37 STK4
 serine/threonine kinase 4
 4251
 0.17
chr14_105955874_105956035 0.37 C14orf80
 chromosome 14 open reading frame 80
 238
 0.86
chr2_74518166_74518317 0.37 SLC4A5
 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
 409
 0.81
chr7_38398847_38399253 0.37 AMPH
 amphiphysin
 103663
 0.08
chr2_109238100_109238434 0.36 LIMS1
 LIM and senescent cell antigen-like domains 1
 545
 0.82
chr7_38389675_38390189 0.36 AMPH
 amphiphysin
 112781
 0.07
chr11_64107928_64108112 0.36 CCDC88B
 coiled-coil domain containing 88B
 325
 0.74
chr2_223288896_223289219 0.36 SGPP2
 sphingosine-1-phosphate phosphatase 2
 179
 0.95
chr9_117148892_117149291 0.36 AKNA
 AT-hook transcription factor
 1152
 0.52
chr7_72300438_72300694 0.35 SBDSP1
 Shwachman-Bodian-Diamond syndrome pseudogene 1
 331
 0.8
chr11_59436048_59436268 0.35 PATL1
 protein associated with topoisomerase II homolog 1 (yeast)
 295
 0.7
chr14_91881184_91881623 0.34 CCDC88C
 coiled-coil domain containing 88C
 2287
 0.37
chr20_45984269_45984938 0.34 ZMYND8
 zinc finger, MYND-type containing 8
 202
 0.91
chr17_38474027_38474267 0.34 RARA
 retinoic acid receptor, alpha
 386
 0.78
chr16_3628507_3629057 0.34 NLRC3
 NLR family, CARD domain containing 3
 1381
 0.35
chr7_73508723_73509010 0.33 LIMK1
 LIM domain kinase 1
 1457
 0.41
chr11_441689_441900 0.33 ANO9
 anoctamin 9
 217
 0.82
chr10_30818195_30818576 0.33 ENSG00000239744
 .
 26448
 0.21
chr2_47339184_47339335 0.33 C2orf61
 chromosome 2 open reading frame 61
 39175
 0.14
chr14_99740123_99740356 0.33 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
 2378
 0.32
chr19_8642129_8642285 0.33 MYO1F
 myosin IF
 115
 0.94
chr15_69110570_69110988 0.33 ANP32A
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 2446
 0.33
chr2_218654884_218655156 0.33 DIRC3
 disrupted in renal carcinoma 3
 33742
 0.19
chr1_225655628_225655947 0.32 RP11-496N12.6
2742
 0.3
chr15_86233199_86233602 0.32 RP11-815J21.1
10940
 0.11
chrX_20284402_20284620 0.32 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
 249
 0.95
chr8_121823290_121823441 0.32 SNTB1
 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
 1018
 0.42
chr6_159803061_159803212 0.32 FNDC1-IT1
 FNDC1 intronic transcript 1 (non-protein coding)
 141318
 0.04
chr17_41734244_41734395 0.32 MEOX1
 mesenchyme homeobox 1
 4612
 0.21
chr6_170262857_170263008 0.31 RP1-266L20.9
92423
 0.07
chr17_73851235_73851456 0.31 WBP2
 WW domain binding protein 2
 39
 0.94
chrX_55478092_55478482 0.31 MAGEH1
 melanoma antigen family H, 1
 251
 0.61
chr5_66461842_66462051 0.31 MAST4
 microtubule associated serine/threonine kinase family member 4
 23684
 0.22
chr7_100075649_100075831 0.31 TSC22D4
 TSC22 domain family, member 4
 1115
 0.26
chr4_109092957_109093342 0.31 ENSG00000232021
 .
 127
 0.97
chr20_37434777_37435281 0.30 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 662
 0.71
chr14_91882732_91883366 0.30 CCDC88C
 coiled-coil domain containing 88C
 641
 0.78
chr19_17862364_17862733 0.30 FCHO1
 FCH domain only 1
 203
 0.91
chr9_130739589_130739875 0.30 FAM102A
 family with sequence similarity 102, member A
 3060
 0.15
chr20_44633478_44633997 0.30 MMP9
 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
 3810
 0.15
chr1_27895293_27895695 0.30 AHDC1
 AT hook, DNA binding motif, containing 1
 34608
 0.12
chr7_38398302_38398591 0.30 AMPH
 amphiphysin
 104267
 0.08
chr2_127838932_127839401 0.30 BIN1
 bridging integrator 1
 25411
 0.22
chr20_62272433_62273064 0.30 STMN3
 stathmin-like 3
 11371
 0.09
chr8_22551057_22551465 0.30 EGR3
 early growth response 3
 446
 0.74
chr7_2551277_2551522 0.30 LFNG
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 764
 0.61
chr14_24585964_24586115 0.30 DCAF11
 DDB1 and CUL4 associated factor 11
 1456
 0.16
chr15_35262065_35262367 0.29 AQR
 aquarius intron-binding spliceosomal factor
 176
 0.95
chr11_66405551_66405805 0.29 RBM4
 RNA binding motif protein 4
 410
 0.71
chr3_151963279_151963566 0.29 MBNL1
 muscleblind-like splicing regulator 1
 22407
 0.21
chr15_99236587_99236738 0.29 IGF1R
 insulin-like growth factor 1 receptor
 14398
 0.24
chr19_39728332_39728587 0.29 IFNL3
 interferon, lambda 3
 7187
 0.12
chr17_70715796_70716056 0.29 ENSG00000222545
 .
 5316
 0.27
chr11_75062885_75063053 0.29 ARRB1
 arrestin, beta 1
 96
 0.96
chr2_64906682_64906833 0.29 SERTAD2
 SERTA domain containing 2
 25710
 0.2
chr6_169719884_169720035 0.29 THBS2
 thrombospondin 2
 65820
 0.14
chr11_5715937_5716088 0.29 TRIM22
 tripartite motif containing 22
 3755
 0.14
chr2_242065104_242065255 0.29 PASK
 PAS domain containing serine/threonine kinase
 13831
 0.13
chr12_109025614_109025806 0.28 SELPLG
 selectin P ligand
 144
 0.94
chr22_39639321_39639607 0.28 PDGFB
 platelet-derived growth factor beta polypeptide
 443
 0.78
chr5_110848363_110849151 0.28 STARD4
 StAR-related lipid transfer (START) domain containing 4
 469
 0.66
chr1_1564774_1565122 0.28 MIB2
 mindbomb E3 ubiquitin protein ligase 2
 1079
 0.29
chr2_240217343_240217562 0.28 ENSG00000265215
 .
 9705
 0.19
chr3_13920477_13920889 0.28 WNT7A
 wingless-type MMTV integration site family, member 7A
 935
 0.64
chr12_12877393_12877751 0.28 RP11-180M15.4
627
 0.56
chr1_36771997_36772148 0.28 SH3D21
 SH3 domain containing 21
 78
 0.96
chr8_145703026_145703200 0.28 FOXH1
 forkhead box H1
 1395
 0.16
chr1_207997059_207997359 0.28 ENSG00000203709
 .
 21341
 0.22
chr19_50002450_50002748 0.27 hsa-mir-150
 hsa-mir-150
 1182
 0.15
chr2_61764720_61765137 0.27 XPO1
 exportin 1 (CRM1 homolog, yeast)
 153
 0.96
chr1_155532313_155532497 0.27 ASH1L
 ash1 (absent, small, or homeotic)-like (Drosophila)
 79
 0.89
chr21_30375506_30375682 0.27 LTN1
 listerin E3 ubiquitin protein ligase 1
 10324
 0.13
chr3_48507282_48507536 0.27 TREX1
 three prime repair exonuclease 1
 64
 0.94
chr1_6674083_6674241 0.27 PHF13
 PHD finger protein 13
 417
 0.47
chr7_43626899_43627416 0.27 STK17A
 serine/threonine kinase 17a
 4493
 0.21
chr10_105343770_105343921 0.27 RP11-416N2.4
24531
 0.13
chr8_27183780_27184189 0.27 PTK2B
 protein tyrosine kinase 2 beta
 356
 0.89
chr17_43326081_43326290 0.27 CTD-2020K17.4
18
 0.93
chr15_78361308_78361764 0.27 TBC1D2B
 TBC1 domain family, member 2B
 3071
 0.18
chrX_118825016_118825167 0.27 SEPT6
 septin 6
 1701
 0.35
chr7_559951_560161 0.27 PDGFA
 platelet-derived growth factor alpha polypeptide
 123
 0.97
chr1_184525111_184525355 0.27 ENSG00000252790
 .
 121835
 0.05
chr12_46662579_46662791 0.27 SLC38A1
 solute carrier family 38, member 1
 93
 0.98
chr2_54787203_54787366 0.26 SPTBN1
 spectrin, beta, non-erythrocytic 1
 1753
 0.36
chr11_44596020_44596237 0.26 CD82
 CD82 molecule
 1500
 0.45
chr16_89790012_89790261 0.26 ZNF276
 zinc finger protein 276
 2184
 0.16
chr15_82337650_82337919 0.26 MEX3B
 mex-3 RNA binding family member B
 676
 0.58
chr10_3822916_3823697 0.26 KLF6
 Kruppel-like factor 6
 4079
 0.25
chr17_8057822_8058074 0.26 PER1
 period circadian clock 1
 1725
 0.16
chrX_153234387_153234741 0.26 HCFC1-AS1
 HCFC1 antisense RNA 1
 212
 0.85
chr4_2538188_2538339 0.26 RNF4
 ring finger protein 4
 46725
 0.12
chr22_50987100_50987359 0.26 KLHDC7B
 kelch domain containing 7B
 767
 0.36
chr12_120730571_120730897 0.26 ENSG00000200795
 .
 306
 0.75
chrY_1604388_1604603 0.26 NA
 NA
 > 106
 NA
chr16_87993193_87993405 0.26 BANP
 BTG3 associated nuclear protein
 178
 0.95
chr8_21768663_21768814 0.26 DOK2
 docking protein 2, 56kDa
 2436
 0.29
chr4_2802491_2802761 0.26 SH3BP2
 SH3-domain binding protein 2
 1901
 0.35
chr14_105190984_105191193 0.26 ADSSL1
 adenylosuccinate synthase like 1
 565
 0.66
chr22_39915742_39916052 0.26 ATF4
 activating transcription factor 4
 197
 0.92
chr19_45756367_45756676 0.26 MARK4
 MAP/microtubule affinity-regulating kinase 4
 1971
 0.24
chr3_126191945_126192170 0.26 ZXDC
 ZXD family zinc finger C
 2651
 0.25
chrX_153209818_153210078 0.25 RENBP
 renin binding protein
 191
 0.87
chr17_46688443_46688779 0.25 HOXB7
 homeobox B7
 232
 0.8
chr2_120988902_120989053 0.25 TMEM185B
 transmembrane protein 185B
 7993
 0.17
chrX_135066962_135067478 0.25 SLC9A6
 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
 378
 0.87
chr7_75247117_75247507 0.25 HIP1
 huntingtin interacting protein 1
 6151
 0.21
chr22_17718076_17718349 0.25 CECR1
 cat eye syndrome chromosome region, candidate 1
 15333
 0.2
chr16_27325519_27325838 0.25 IL4R
 interleukin 4 receptor
 365
 0.88
chr9_114670331_114670482 0.25 UGCG
 UDP-glucose ceramide glucosyltransferase
 11360
 0.19
chr7_66459951_66460466 0.25 SBDS
 Shwachman-Bodian-Diamond syndrome
 380
 0.8
chr6_11852612_11852763 0.25 ADTRP
 androgen-dependent TFPI-regulating protein
 45408
 0.18
chr5_54357840_54358274 0.25 ENSG00000240535
 .
 19385
 0.12
chr11_20178453_20178604 0.25 DBX1
 developing brain homeobox 1
 3342
 0.3
chr19_14494334_14494521 0.25 CD97
 CD97 molecule
 2171
 0.24
chr10_100206295_100206446 0.25 HPS1
 Hermansky-Pudlak syndrome 1
 297
 0.9
chr9_136933745_136934121 0.25 BRD3
 bromodomain containing 3
 276
 0.9
chr11_65245254_65245540 0.25 AP000769.1
 Uncharacterized protein
 22669
 0.1
chr11_128560541_128560759 0.25 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 1739
 0.33
chr10_73532392_73533248 0.25 C10orf54
 chromosome 10 open reading frame 54
 435
 0.83
chr20_35273778_35274551 0.25 SLA2
 Src-like-adaptor 2
 120
 0.95
chr17_77216598_77216760 0.25 RBFOX3
 RNA binding protein, fox-1 homolog (C. elegans) 3
 12041
 0.25
chr1_32719471_32719691 0.25 LCK
 lymphocyte-specific protein tyrosine kinase
 2706
 0.13
chr6_20366920_20367071 0.24 E2F3
 E2F transcription factor 3
 35403
 0.15
chr2_106392347_106392498 0.24 NCK2
 NCK adaptor protein 2
 30234
 0.23
chr1_109731202_109731353 0.24 ENSG00000238310
 .
 19193
 0.13
chr2_85805589_85805940 0.24 VAMP8
 vesicle-associated membrane protein 8
 1048
 0.31
chr22_37681278_37681429 0.24 CYTH4
 cytohesin 4
 2825
 0.23
chr19_3028691_3029066 0.24 TLE2
 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
 133
 0.94
chr1_2171913_2172064 0.24 SKI
 v-ski avian sarcoma viral oncogene homolog
 11854
 0.13
chrX_56594998_56595149 0.24 UBQLN2
 ubiquilin 2
 5047
 0.35
chr11_128385138_128385356 0.24 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 6849
 0.24
chr17_74270163_74270314 0.24 QRICH2
 glutamine rich 2
 6200
 0.13
chr1_95261518_95261669 0.24 SLC44A3
 solute carrier family 44, member 3
 24305
 0.19
chr2_101179059_101179268 0.24 PDCL3
 phosducin-like 3
 11
 0.97
chr12_51763202_51763353 0.24 GALNT6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
 14070
 0.14
chr11_62104656_62104900 0.24 ASRGL1
 asparaginase like 1
 142
 0.88
chr15_66083482_66084093 0.24 DENND4A
 DENN/MADD domain containing 4A
 675
 0.68
chr1_9688741_9688898 0.24 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 22971
 0.15
chr14_103285531_103285798 0.24 TRAF3
 TNF receptor-associated factor 3
 11027
 0.17
chr2_113931904_113932161 0.24 PSD4
 pleckstrin and Sec7 domain containing 4
 458
 0.63
chr6_31544266_31544562 0.24 TNF
 tumor necrosis factor
 1070
 0.2
chr6_149803641_149803913 0.24 ZC3H12D
 zinc finger CCCH-type containing 12D
 492
 0.77
chr2_106371033_106371184 0.24 NCK2
 NCK adaptor protein 2
 8920
 0.3
chr16_27417712_27417863 0.24 IL21R
 interleukin 21 receptor
 3364
 0.26
chr7_129008169_129008353 0.23 AHCYL2
 adenosylhomocysteinase-like 2
 279
 0.92
chr20_39768343_39768494 0.23 RP1-1J6.2
1775
 0.34
chr17_48229617_48229817 0.23 PPP1R9B
 protein phosphatase 1, regulatory subunit 9B
 1840
 0.19
chr6_30798000_30798388 0.23 ENSG00000202241
 .
 33833
 0.07
chr14_24912216_24912414 0.23 SDR39U1
 short chain dehydrogenase/reductase family 39U, member 1
 251
 0.86
chr9_20622216_20622410 0.23 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
 201
 0.95
chr7_97840727_97841036 0.23 BHLHA15
 basic helix-loop-helix family, member a15
 142
 0.96
chr17_8867224_8867375 0.23 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 1725
 0.44
chrX_51138603_51139026 0.23 RP11-348F1.3
500
 0.83
chr12_123757067_123757218 0.23 CDK2AP1
 cyclin-dependent kinase 2 associated protein 1
 261
 0.86
chr11_67186046_67186291 0.23 PPP1CA
 protein phosphatase 1, catalytic subunit, alpha isozyme
 2484
 0.1
chr1_43397747_43398281 0.23 SLC2A1
 solute carrier family 2 (facilitated glucose transporter), member 1
 1218
 0.47
chr19_45250951_45251364 0.23 BCL3
 B-cell CLL/lymphoma 3
 647
 0.57
chr19_49014061_49014374 0.23 LMTK3
 lemur tyrosine kinase 3
 844
 0.46
chr14_24021172_24021323 0.23 ZFHX2
 zinc finger homeobox 2
 389
 0.73
chr1_206644682_206644833 0.23 IKBKE
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
 919
 0.51
chr9_19126551_19126793 0.22 PLIN2
 perilipin 2
 802
 0.55
chr17_81039428_81039659 0.22 METRNL
 meteorin, glial cell differentiation regulator-like
 1468
 0.47
chr5_137801693_137801976 0.22 EGR1
 early growth response 1
 655
 0.68

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.6 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 0.3 GO:0072224 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.1 0.5 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.3 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.6 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.1 0.2 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.2 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.2 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.2 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.4 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.3 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:2000380 regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.0 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.3 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.0 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0021894 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:1902019 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0014052 gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239)
0.0 0.0 GO:1901021 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0021694 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0032493 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.4 GO:0075733 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.1 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0072676 lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0 0.5 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.4 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:2001235 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0052173 modulation by symbiont of host defense response(GO:0052031) response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) response to host(GO:0075136)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0021612 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) anatomical structure arrangement(GO:0048532)
0.0 0.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.0 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.0 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.5 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
0.0 0.0 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.1 GO:0007398 ectoderm development(GO:0007398)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.0 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:2000192 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.0 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:1901072 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.0 GO:0031063 regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0 0.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.0 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.0 GO:0048305 immunoglobulin secretion(GO:0048305) regulation of immunoglobulin secretion(GO:0051023)
0.0 0.0 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.0 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0031143 pseudopodium(GO:0031143)
0.1 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.0 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.0 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0030891 VCB complex(GO:0030891)
0.0 0.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.3 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.1 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.6 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.5 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.8 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.2 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.6 GO:0042393 histone binding(GO:0042393)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.0 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex