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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for RXRA_NR2F6_NR2C2

Z-value: 1.10

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Transcription factors associated with RXRA_NR2F6_NR2C2

Gene Symbol Gene ID Gene Info
RXRA
ENSG00000186350.8 retinoid X receptor alpha
NR2F6
ENSG00000160113.5 nuclear receptor subfamily 2 group F member 6
NR2C2
ENSG00000177463.11 nuclear receptor subfamily 2 group C member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_15030879_15031030NR2C2144680.2015690.646.1e-02Click!
chr3_15001001_15001179NR2C228240.283320-0.481.9e-01Click!
chr3_15052457_15052608NR2C271100.219334-0.225.8e-01Click!
chr3_15030493_15030644NR2C2148540.2006870.176.5e-01Click!
chr3_15028082_15028233NR2C2172650.1951050.137.5e-01Click!
chr19_17356354_17356505NR2F63200.7388090.333.8e-01Click!
chr19_17355272_17355498NR2F6720.926116-0.324.0e-01Click!
chr19_17355503_17355912NR2F63940.668365-0.206.1e-01Click!
chr19_17357023_17357252NR2F63880.672975-0.108.1e-01Click!
chr19_17355975_17356268NR2F66280.474279-0.068.8e-01Click!
chr9_137296411_137296683RXRA18810.4102030.853.7e-03Click!
chr9_137326628_137326779RXRA282750.207889-0.826.6e-03Click!
chr9_137160017_137160168RXRA583340.1295730.781.3e-02Click!
chr9_137335451_137335655RXRA371250.1855350.742.1e-02Click!
chr9_137297323_137297474RXRA10300.6135470.723.0e-02Click!

Activity of the RXRA_NR2F6_NR2C2 motif across conditions

Conditions sorted by the z-value of the RXRA_NR2F6_NR2C2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_10416066_10416280 0.96 ZGLP1
 zinc finger, GATA-like protein 1
 4286
 0.08
chr17_79879240_79879391 0.65 SIRT7
 sirtuin 7
 116
 0.85
chr6_14721018_14721200 0.62 ENSG00000206960
 .
 74343
 0.13
chrX_65235295_65235677 0.61 ENSG00000207939
 .
 3226
 0.26
chr12_54694994_54695195 0.60 COPZ1
 coatomer protein complex, subunit zeta 1
 108
 0.6
chr12_1922066_1922217 0.58 CACNA2D4
 calcium channel, voltage-dependent, alpha 2/delta subunit 4
 1184
 0.5
chr22_37260110_37260261 0.56 NCF4
 neutrophil cytosolic factor 4, 40kDa
 3155
 0.18
chr14_73931523_73931791 0.54 ENSG00000251393
 .
 2528
 0.22
chr10_129678816_129678967 0.50 CLRN3
 clarin 3
 12320
 0.22
chr16_47050823_47051091 0.49 RP11-169E6.1
43057
 0.14
chr9_70850762_70850954 0.45 CBWD3
 COBW domain containing 3
 5539
 0.19
chr7_143078673_143079796 0.45 ZYX
 zyxin
 234
 0.85
chr11_1781045_1781196 0.43 AC068580.6
458
 0.52
chr6_109561771_109561922 0.42 ENSG00000238474
 .
 50715
 0.12
chr19_18334931_18335362 0.42 PDE4C
 phosphodiesterase 4C, cAMP-specific
 157
 0.91
chr6_13274566_13274804 0.42 RP1-257A7.4
394
 0.82
chr17_81011742_81011893 0.41 B3GNTL1
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
 2131
 0.35
chr2_60783649_60784435 0.41 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 3340
 0.31
chr20_4807814_4807965 0.40 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 3598
 0.24
chr4_6927779_6927930 0.39 TBC1D14
 TBC1 domain family, member 14
 15879
 0.16
chr3_171684620_171684771 0.37 TMEM212-IT1
 TMEM212 intronic transcript 1 (non-protein coding)
 72469
 0.1
chr11_72448382_72448649 0.37 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
 10342
 0.12
chr15_77711149_77711991 0.37 PEAK1
 pseudopodium-enriched atypical kinase 1
 872
 0.51
chr9_35685699_35685887 0.36 TPM2
 tropomyosin 2 (beta)
 330
 0.73
chr6_31927037_31927267 0.35 SKIV2L
 superkiller viralicidic activity 2-like (S. cerevisiae)
 204
 0.52
chr9_69268507_69268733 0.35 CBWD6
 COBW domain containing 6
 6027
 0.21
chr18_2049997_2050208 0.35 METTL4
 methyltransferase like 4
 504589
 0.0
chr1_153362333_153362484 0.35 S100A8
 S100 calcium binding protein A8
 1044
 0.37
chr14_20896169_20896332 0.34 KLHL33
 kelch-like family member 33
 7551
 0.08
chr11_113954202_113954403 0.34 ENSG00000221112
 .
 3349
 0.28
chr19_47234689_47234868 0.34 CTB-174O21.2
2918
 0.12
chr5_36067012_36067195 0.34 UGT3A2
 UDP glycosyltransferase 3 family, polypeptide A2
 110
 0.97
chr17_7123160_7124223 0.34 ACADVL
 acyl-CoA dehydrogenase, very long chain
 424
 0.48
chr11_22688489_22688994 0.33 GAS2
 growth arrest-specific 2
 119
 0.97
chr12_56537034_56537185 0.33 MYL6B
 myosin, light chain 6B, alkali, smooth muscle and non-muscle
 8931
 0.06
chr2_219646650_219647418 0.33 CYP27A1
 cytochrome P450, family 27, subfamily A, polypeptide 1
 555
 0.7
chr16_1990929_1991093 0.32 MSRB1
 methionine sulfoxide reductase B1
 2113
 0.1
chr22_32033546_32033968 0.32 PISD
 phosphatidylserine decarboxylase
 634
 0.74
chr20_4943157_4943308 0.32 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 38913
 0.14
chr1_33463602_33463869 0.32 RP1-117O3.2
11059
 0.14
chr2_113592071_113592291 0.31 IL1B
 interleukin 1, beta
 1830
 0.31
chr2_234257769_234257933 0.31 RP11-400N9.1
4211
 0.17
chr7_41731347_41731498 0.31 INHBA-AS1
 INHBA antisense RNA 1
 2092
 0.34
chr8_38722630_38723350 0.30 RP11-723D22.3
19033
 0.16
chr8_68880458_68880609 0.30 PREX2
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
 16180
 0.28
chr15_49087139_49087290 0.30 RP11-485O10.2
11827
 0.17
chr1_226374129_226374763 0.30 ACBD3
 acyl-CoA binding domain containing 3
 15
 0.98
chr20_62713551_62713939 0.30 C20orf201
 chromosome 20 open reading frame 201
 1967
 0.15
chr1_12079558_12080233 0.30 MIIP
 migration and invasion inhibitory protein
 305
 0.84
chr12_96514891_96515042 0.30 ENSG00000266889
 .
 18939
 0.19
chr19_10362934_10363426 0.30 MRPL4
 mitochondrial ribosomal protein L4
 228
 0.83
chr2_232545912_232546437 0.29 MGC4771
25447
 0.14
chr1_2987231_2987751 0.29 PRDM16
 PR domain containing 16
 1716
 0.34
chr19_6738037_6738395 0.29 TRIP10
 thyroid hormone receptor interactor 10
 280
 0.7
chr10_73511646_73511797 0.28 C10orf54
 chromosome 10 open reading frame 54
 5666
 0.21
chr1_235091297_235091455 0.28 ENSG00000239690
 .
 51443
 0.16
chr21_39756340_39756646 0.28 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 87645
 0.09
chr17_48367766_48367999 0.28 RP11-893F2.9
2666
 0.19
chrX_117858717_117858999 0.28 IL13RA1
 interleukin 13 receptor, alpha 1
 2677
 0.32
chr14_60620645_60620999 0.28 DHRS7
 dehydrogenase/reductase (SDR family) member 7
 930
 0.61
chr15_53495921_53496072 0.27 ONECUT1
 one cut homeobox 1
 413787
 0.01
chrX_2809831_2809982 0.27 ARSD-AS1
 ARSD antisense RNA 1
 13039
 0.15
chr16_28506110_28506360 0.27 APOBR
 apolipoprotein B receptor
 242
 0.75
chr11_72527375_72527681 0.27 ATG16L2
 autophagy related 16-like 2 (S. cerevisiae)
 2051
 0.23
chr12_54688592_54688942 0.27 NFE2
 nuclear factor, erythroid 2
 775
 0.4
chr22_51020587_51021277 0.27 CHKB
 choline kinase beta
 496
 0.39
chr20_1876393_1876635 0.27 SIRPA
 signal-regulatory protein alpha
 572
 0.81
chr20_48808829_48809749 0.26 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
 1913
 0.35
chr6_149450767_149450918 0.26 ENSG00000263481
 .
 47088
 0.15
chr16_85325294_85325445 0.26 ENSG00000266307
 .
 14562
 0.24
chr13_114271046_114271197 0.26 TFDP1
 transcription factor Dp-1
 31380
 0.15
chr19_43849967_43850118 0.26 CD177
 CD177 molecule
 7783
 0.17
chr8_33412041_33412395 0.26 RNF122
 ring finger protein 122
 12425
 0.13
chr7_106065721_106066226 0.26 CTB-111H14.1
79312
 0.1
chr11_6656944_6657095 0.26 RP11-732A19.6
5185
 0.09
chr19_48866469_48867161 0.26 TMEM143
 transmembrane protein 143
 116
 0.89
chr19_36399282_36399433 0.26 TYROBP
 TYRO protein tyrosine kinase binding protein
 160
 0.9
chr12_109122720_109122871 0.26 CORO1C
 coronin, actin binding protein, 1C
 1532
 0.34
chr15_70384544_70384773 0.26 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
 2466
 0.34
chr3_64811829_64811980 0.25 ADAMTS9
 ADAM metallopeptidase with thrombospondin type 1 motif, 9
 138228
 0.05
chr17_48205902_48206073 0.25 SAMD14
 sterile alpha motif domain containing 14
 1131
 0.31
chr17_4615541_4615774 0.25 ARRB2
 arrestin, beta 2
 1663
 0.18
chr2_113945024_113945175 0.25 PSD4
 pleckstrin and Sec7 domain containing 4
 8758
 0.14
chr17_29701117_29701268 0.25 NF1
 neurofibromin 1
 15626
 0.14
chr15_99417963_99418437 0.25 IGF1R
 insulin-like growth factor 1 receptor
 15370
 0.2
chr2_7075634_7075785 0.25 RNF144A
 ring finger protein 144A
 2535
 0.29
chr1_160832331_160832502 0.25 CD244
 CD244 molecule, natural killer cell receptor 2B4
 74
 0.97
chr19_43891664_43891815 0.25 TEX101
 testis expressed 101
 13909
 0.15
chr18_2984866_2985017 0.24 LPIN2
 lipin 2
 2070
 0.27
chr10_73456429_73456580 0.24 C10orf105
 chromosome 10 open reading frame 105
 23074
 0.2
chr10_14730758_14730909 0.24 ENSG00000201766
 .
 25340
 0.19
chr6_56668655_56668840 0.24 DST
 dystonin
 18070
 0.23
chr7_95238082_95238332 0.24 AC002451.3
901
 0.62
chr1_236056109_236056279 0.24 LYST
 lysosomal trafficking regulator
 9322
 0.17
chr7_139530944_139531095 0.24 TBXAS1
 thromboxane A synthase 1 (platelet)
 1909
 0.44
chr12_129338589_129338740 0.24 GLT1D1
 glycosyltransferase 1 domain containing 1
 583
 0.82
chr20_32399297_32399983 0.24 CHMP4B
 charged multivesicular body protein 4B
 530
 0.55
chr12_111843881_111845308 0.23 SH2B3
 SH2B adaptor protein 3
 842
 0.62
chr20_17660855_17661298 0.23 RRBP1
 ribosome binding protein 1
 1629
 0.4
chr11_67043892_67044043 0.23 ADRBK1
 adrenergic, beta, receptor kinase 1
 10015
 0.11
chr5_77306460_77306689 0.23 AP3B1
 adaptor-related protein complex 3, beta 1 subunit
 28400
 0.21
chr1_147119514_147119665 0.23 ACP6
 acid phosphatase 6, lysophosphatidic
 11527
 0.22
chr5_149465296_149465474 0.23 CSF1R
 colony stimulating factor 1 receptor
 605
 0.69
chr10_30831582_30831733 0.23 ENSG00000239744
 .
 13176
 0.24
chrX_19904584_19904836 0.23 SH3KBP1
 SH3-domain kinase binding protein 1
 867
 0.7
chr16_66638822_66640143 0.23 CMTM3
 CKLF-like MARVEL transmembrane domain containing 3
 58
 0.95
chrX_153659493_153659733 0.22 ATP6AP1
 ATPase, H+ transporting, lysosomal accessory protein 1
 2604
 0.11
chr19_1154555_1155129 0.22 SBNO2
 strawberry notch homolog 2 (Drosophila)
 293
 0.85
chr7_105317322_105317473 0.22 ATXN7L1
 ataxin 7-like 1
 2212
 0.41
chr7_99954721_99954872 0.22 PILRB
 paired immunoglobin-like type 2 receptor beta
 207
 0.86
chr21_44158180_44158391 0.22 AP001627.1
3583
 0.28
chr8_142105945_142106235 0.22 DENND3
 DENN/MADD domain containing 3
 21287
 0.19
chr15_74232964_74233156 0.22 LOXL1-AS1
 LOXL1 antisense RNA 1
 12471
 0.14
chr11_47416116_47416267 0.22 RP11-750H9.5
1000
 0.33
chr11_75474128_75474279 0.22 DGAT2
 diacylglycerol O-acyltransferase 2
 3646
 0.13
chr19_1068246_1068401 0.22 HMHA1
 histocompatibility (minor) HA-1
 826
 0.4
chr6_76317008_76317159 0.22 SENP6
 SUMO1/sentrin specific peptidase 6
 5320
 0.19
chr19_676350_676550 0.21 FSTL3
 follistatin-like 3 (secreted glycoprotein)
 58
 0.95
chr20_31061401_31061552 0.21 C20orf112
 chromosome 20 open reading frame 112
 9798
 0.18
chr7_40591526_40591750 0.21 AC004988.1
5111
 0.35
chr9_35730052_35730203 0.21 CREB3
 cAMP responsive element binding protein 3
 2205
 0.12
chr12_562387_562595 0.21 B4GALNT3
 beta-1,4-N-acetyl-galactosaminyl transferase 3
 7039
 0.21
chr1_23850782_23850933 0.21 E2F2
 E2F transcription factor 2
 6855
 0.18
chr18_9827953_9828104 0.21 ENSG00000242651
 .
 2596
 0.28
chr9_110253387_110253828 0.21 KLF4
 Kruppel-like factor 4 (gut)
 844
 0.66
chr11_121325996_121326147 0.21 RP11-730K11.1
2349
 0.33
chr6_110118234_110118385 0.21 FIG4
 FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
 11100
 0.28
chr9_184980_185177 0.21 CBWD1
 COBW domain containing 1
 6006
 0.2
chr20_36824815_36825080 0.20 TGM2
 transglutaminase 2
 29967
 0.14
chr10_98418237_98418708 0.20 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 10896
 0.21
chr22_31625332_31625483 0.20 ENSG00000202019
 .
 751
 0.5
chr10_29977190_29977386 0.20 ENSG00000222092
 .
 23556
 0.21
chr9_123500093_123500244 0.20 MEGF9
 multiple EGF-like-domains 9
 23420
 0.2
chr17_25859259_25859414 0.20 KSR1
 kinase suppressor of ras 1
 50611
 0.13
chr6_131895362_131895513 0.20 ARG1
 arginase 1
 1072
 0.55
chr16_57126935_57127447 0.20 CPNE2
 copine II
 672
 0.49
chr15_58438968_58439119 0.20 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
 8019
 0.23
chr2_85727105_85727457 0.20 ENSG00000266577
 .
 32468
 0.08
chr19_6067059_6067210 0.20 CTC-232P5.3
830
 0.55
chr11_47416652_47416817 0.20 RP11-750H9.5
457
 0.65
chr1_12046473_12046624 0.20 MFN2
 mitofusin 2
 4499
 0.15
chr22_36795299_36795450 0.20 MYH9
 myosin, heavy chain 9, non-muscle
 11311
 0.17
chr16_20756487_20756638 0.20 THUMPD1
 THUMP domain containing 1
 3156
 0.18
chr17_36584744_36585461 0.20 ARHGAP23
 Rho GTPase activating protein 23
 372
 0.84
chr3_53201341_53201492 0.19 PRKCD
 protein kinase C, delta
 2271
 0.28
chr16_90033999_90034150 0.19 RP11-566K11.5
2125
 0.18
chr2_102609682_102609833 0.19 IL1R2
 interleukin 1 receptor, type II
 1451
 0.51
chr7_76033306_76033511 0.19 SRCRB4D
 scavenger receptor cysteine rich domain containing, group B (4 domains)
 5604
 0.17
chr6_33172447_33173020 0.19 HSD17B8
 hydroxysteroid (17-beta) dehydrogenase 8
 314
 0.73
chr6_49603951_49604102 0.19 RHAG
 Rh-associated glycoprotein
 526
 0.83
chr2_27602964_27603512 0.19 ZNF513
 zinc finger protein 513
 73
 0.93
chr1_169861896_169862644 0.19 SCYL3
 SCY1-like 3 (S. cerevisiae)
 806
 0.65
chr13_108974971_108975122 0.19 ENSG00000223177
 .
 21367
 0.23
chr12_89551363_89551514 0.19 ENSG00000238302
 .
 124624
 0.06
chr17_73305250_73305401 0.19 GRB2
 growth factor receptor-bound protein 2
 12509
 0.09
chr1_174938035_174938186 0.19 RABGAP1L
 RAB GTPase activating protein 1-like
 4205
 0.17
chr5_101631358_101631636 0.19 SLCO4C1
 solute carrier organic anion transporter family, member 4C1
 756
 0.68
chr2_70172880_70173031 0.19 ENSG00000239072
 .
 9822
 0.12
chr2_113190375_113190911 0.19 RGPD8
 RANBP2-like and GRIP domain containing 8
 453
 0.86
chr19_12899418_12899647 0.19 ENSG00000263800
 .
 1590
 0.15
chr19_42133062_42133277 0.19 CEACAM4
 carcinoembryonic antigen-related cell adhesion molecule 4
 273
 0.89
chr12_105122483_105122634 0.19 ENSG00000222579
 .
 123044
 0.05
chr9_117895091_117895381 0.18 DEC1
 deleted in esophageal cancer 1
 8861
 0.25
chr4_353397_353548 0.18 ENSG00000207642
 .
 9526
 0.17
chr2_61153613_61153764 0.18 ENSG00000201076
 .
 15250
 0.18
chr1_156474559_156474783 0.18 MEF2D
 myocyte enhancer factor 2D
 4051
 0.14
chr7_642417_642568 0.18 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
 172
 0.69
chr17_77005019_77005688 0.18 CANT1
 calcium activated nucleotidase 1
 459
 0.76
chr16_89042423_89042673 0.18 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
 853
 0.55
chr11_85781008_85781159 0.18 PICALM
 phosphatidylinositol binding clathrin assembly protein
 159
 0.96
chr3_37284874_37285642 0.18 RP11-259K5.2
410
 0.48
chr22_37257050_37257437 0.18 NCF4
 neutrophil cytosolic factor 4, 40kDa
 213
 0.91
chr2_136690107_136690258 0.18 DARS
 aspartyl-tRNA synthetase
 12059
 0.21
chr1_33812503_33812654 0.18 PHC2
 polyhomeotic homolog 2 (Drosophila)
 2908
 0.16
chr1_154989875_154990097 0.18 ZBTB7B
 zinc finger and BTB domain containing 7B
 3062
 0.1
chr9_34179429_34180002 0.18 UBAP1
 ubiquitin associated protein 1
 679
 0.62
chr1_10475436_10475736 0.18 APITD1
 apoptosis-inducing, TAF9-like domain 1
 14573
 0.1
chr1_155202832_155202983 0.18 ENSG00000216109
 .
 3721
 0.07
chr15_57071498_57071649 0.18 ZNF280D
 zinc finger protein 280D
 45289
 0.19
chr10_21814018_21814991 0.18 SKIDA1
 SKI/DACH domain containing 1
 107
 0.95
chr1_99729766_99730318 0.18 LPPR4
 Lipid phosphate phosphatase-related protein type 4
 194
 0.97
chrX_118894160_118894311 0.18 SOWAHD
 sosondowah ankyrin repeat domain family member D
 1659
 0.32
chr1_38467251_38467531 0.18 FHL3
 four and a half LIM domains 3
 3786
 0.15
chr15_40625954_40626153 0.18 ENSG00000252714
 .
 2204
 0.13
chr2_45170446_45170597 0.18 SIX3-AS1
 SIX3 antisense RNA 1
 1509
 0.36
chrX_138285953_138286466 0.17 FGF13
 fibroblast growth factor 13
 60
 0.99
chr2_231735442_231735593 0.17 ITM2C
 integral membrane protein 2C
 5138
 0.19
chr9_139928371_139928559 0.17 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 1003
 0.23
chr9_134460250_134460544 0.17 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 36828
 0.13
chr2_11828981_11829132 0.17 AC106875.1
7469
 0.13
chr5_124083658_124084316 0.17 ZNF608
 zinc finger protein 608
 513
 0.71
chr9_35489468_35490886 0.17 RUSC2
 RUN and SH3 domain containing 2
 53
 0.97
chr1_92941939_92942090 0.17 GFI1
 growth factor independent 1 transcription repressor
 7497
 0.27
chr20_30125745_30125896 0.17 HM13
 histocompatibility (minor) 13
 23496
 0.1
chr19_16482178_16482409 0.17 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 9529
 0.15
chr17_75382520_75382671 0.17 SEPT9
 septin 9
 6390
 0.17
chr19_1019836_1021109 0.17 TMEM259
 transmembrane protein 259
 373
 0.62
chr3_10231486_10231637 0.17 IRAK2
 interleukin-1 receptor-associated kinase 2
 25012
 0.1
chrX_118894330_118894481 0.17 SOWAHD
 sosondowah ankyrin repeat domain family member D
 1829
 0.3
chr17_1090163_1090534 0.17 ABR
 active BCR-related
 268
 0.91

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRA_NR2F6_NR2C2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.1 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.4 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.1 0.2 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1 0.4 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.0 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.0 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0046719 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0045217 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.2 GO:0033003 regulation of mast cell activation(GO:0033003)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.0 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0033605 positive regulation of catecholamine secretion(GO:0033605)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.0 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.0 GO:0003160 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.5 GO:0044452 nucleolar part(GO:0044452)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0038201 TOR complex(GO:0038201)
0.0 0.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.2 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0032129 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H3-K9 specific)(GO:0032129) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent protein deacetylase activity(GO:0034979) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.0 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.0 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules