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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SCRT1_SCRT2

Z-value: 1.20

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
SCRT1
ENSG00000170616.9 SCRT1
SCRT2
ENSG00000215397.3 SCRT2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
SCRT1chr8_145555817_14555606440030.086085-0.752.0e-02Click!
SCRT1chr8_145560876_14556104910190.2771400.521.5e-01Click!
SCRT1chr8_145561219_14556146113970.193360-0.314.1e-01Click!
SCRT1chr8_145555468_14555561944000.082971-0.265.0e-01Click!
SCRT1chr8_145562079_14556223022110.122634-0.147.3e-01Click!
SCRT2chr20_656859_6570101110.8537960.481.9e-01Click!
SCRT2chr20_657176_6573274280.6590450.284.7e-01Click!

Activity of the SCRT1_SCRT2 motif across conditions

Conditions sorted by the z-value of the SCRT1_SCRT2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_112573817_112573968 0.99 LAMA4
 laminin, alpha 4
 1795
 0.35
chr4_169553568_169553728 0.83 PALLD
 palladin, cytoskeletal associated protein
 880
 0.63
chrX_99986862_99987124 0.83 SYTL4
 synaptotagmin-like 4
 114
 0.97
chr6_121756849_121757212 0.72 GJA1
 gap junction protein, alpha 1, 43kDa
 192
 0.94
chr3_186505500_186505651 0.66 ENSG00000263776
 .
 174
 0.69
chr3_55515212_55515397 0.65 WNT5A
 wingless-type MMTV integration site family, member 5A
 80
 0.98
chr5_89854556_89855048 0.62 GPR98
 G protein-coupled receptor 98
 185
 0.96
chr5_150161983_150162220 0.61 AC010441.1
4234
 0.18
chr20_30300696_30301130 0.60 AL160175.1
8088
 0.13
chr10_63813819_63813970 0.60 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 4924
 0.3
chr3_44038033_44038921 0.57 ENSG00000252980
 .
 74102
 0.11
chr5_138680031_138680182 0.56 PAIP2
 poly(A) binding protein interacting protein 2
 1966
 0.19
chr20_25213879_25214247 0.56 AL035252.1
 HCG2018895; Uncharacterized protein
 6693
 0.16
chr3_25471508_25471659 0.55 RARB
 retinoic acid receptor, beta
 1781
 0.47
chr12_71003154_71004126 0.55 PTPRB
 protein tyrosine phosphatase, receptor type, B
 16
 0.99
chr20_55206861_55207029 0.54 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 1007
 0.5
chr6_41336919_41337070 0.54 ENSG00000238867
 .
 13807
 0.17
chr9_114671696_114672066 0.53 UGCG
 UDP-glucose ceramide glucosyltransferase
 12835
 0.19
chr15_30113385_30113906 0.53 TJP1
 tight junction protein 1
 106
 0.95
chr7_19144831_19144982 0.53 AC003986.6
7191
 0.17
chr5_15500207_15500358 0.52 FBXL7
 F-box and leucine-rich repeat protein 7
 23
 0.99
chr14_53418107_53419061 0.52 FERMT2
 fermitin family member 2
 569
 0.83
chr8_122650853_122651057 0.51 HAS2-AS1
 HAS2 antisense RNA 1
 578
 0.78
chr2_217559691_217559970 0.51 IGFBP5
 insulin-like growth factor binding protein 5
 313
 0.72
chr3_43995391_43995578 0.51 ENSG00000252980
 .
 117095
 0.06
chr1_215256963_215257162 0.51 KCNK2
 potassium channel, subfamily K, member 2
 202
 0.97
chr20_36154288_36154588 0.51 BLCAP
 bladder cancer associated protein
 1485
 0.45
chr16_2286497_2287265 0.49 DNASE1L2
 deoxyribonuclease I-like 2
 54
 0.91
chr2_70442433_70442584 0.49 TIA1
 TIA1 cytotoxic granule-associated RNA binding protein
 13942
 0.14
chrX_128787954_128788123 0.49 APLN
 apelin
 876
 0.69
chr3_185677710_185678274 0.48 RP11-443P15.2
164
 0.95
chr5_10306978_10307734 0.48 CMBL
 carboxymethylenebutenolidase homolog (Pseudomonas)
 782
 0.53
chr20_43971537_43971915 0.48 SDC4
 syndecan 4
 5338
 0.13
chr9_4339562_4339725 0.48 ENSG00000221730
 .
 38851
 0.13
chr4_41157747_41157945 0.48 ENSG00000207198
 .
 41887
 0.14
chr2_101437792_101437972 0.48 NPAS2
 neuronal PAS domain protein 2
 395
 0.8
chr6_42109948_42110375 0.47 C6orf132
 chromosome 6 open reading frame 132
 21
 0.97
chr11_27743435_27743805 0.46 BDNF
 brain-derived neurotrophic factor
 15
 0.99
chr8_58660509_58660660 0.46 ENSG00000252057
 .
 191440
 0.03
chr6_130689068_130689442 0.46 TMEM200A
 transmembrane protein 200A
 2376
 0.3
chr6_164616629_164616780 0.45 ENSG00000266128
 .
 355111
 0.01
chr4_177365034_177365248 0.45 RP11-87F15.2
123532
 0.05
chr5_32712676_32712984 0.45 NPR3
 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
 393
 0.9
chr8_104155072_104155223 0.45 C8orf56
 chromosome 8 open reading frame 56
 1444
 0.27
chr12_3232327_3232575 0.45 TSPAN9-IT1
 TSPAN9 intronic transcript 1 (non-protein coding)
 26512
 0.19
chr19_46974752_46975184 0.45 PNMAL1
 paraneoplastic Ma antigen family-like 1
 148
 0.94
chr10_27547544_27548544 0.44 ARMC4P1
 armadillo repeat containing 4 pseudogene 1
 3842
 0.17
chr22_45900582_45901194 0.44 FBLN1
 fibulin 1
 1962
 0.36
chr18_61616540_61617060 0.44 HMSD
 histocompatibility (minor) serpin domain containing
 265
 0.9
chr12_16759185_16759513 0.43 LMO3
 LIM domain only 3 (rhombotin-like 2)
 116
 0.98
chr1_95392942_95393358 0.43 RP4-639F20.1
28
 0.82
chr4_148402515_148403207 0.43 EDNRA
 endothelin receptor type A
 777
 0.76
chr1_60599792_60599943 0.42 C1orf87
 chromosome 1 open reading frame 87
 60425
 0.15
chr5_111090218_111090459 0.42 NREP
 neuronal regeneration related protein
 1610
 0.42
chr4_101111713_101112234 0.41 DDIT4L
 DNA-damage-inducible transcript 4-like
 34
 0.95
chr10_23216488_23217262 0.41 ARMC3
 armadillo repeat containing 3
 78
 0.98
chr5_137474933_137475144 0.41 NME5
 NME/NM23 family member 5
 66
 0.95
chr8_77316107_77316384 0.41 ENSG00000222231
 .
 138278
 0.05
chr18_52495652_52496658 0.41 RAB27B
 RAB27B, member RAS oncogene family
 725
 0.77
chr11_73022764_73022915 0.41 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
 229
 0.89
chr11_93885194_93885476 0.41 PANX1
 pannexin 1
 23240
 0.23
chr4_41258452_41258603 0.40 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
 97
 0.66
chr13_42490447_42490670 0.40 ENSG00000206962
 .
 11304
 0.24
chr1_220101375_220102142 0.40 SLC30A10
 solute carrier family 30, member 10
 186
 0.95
chr5_59893443_59893927 0.40 DEPDC1B
 DEP domain containing 1B
 102276
 0.07
chr6_11196915_11197406 0.39 RP3-510L9.1
23475
 0.18
chr1_151962822_151962989 0.39 S100A10
 S100 calcium binding protein A10
 2149
 0.24
chr12_120935516_120935667 0.39 DYNLL1
 dynein, light chain, LC8-type 1
 1675
 0.19
chr5_155108981_155109215 0.39 ENSG00000200275
 .
 163349
 0.04
chr6_129820127_129820286 0.39 RP1-69D17.3
17651
 0.26
chr3_179754024_179754473 0.38 PEX5L
 peroxisomal biogenesis factor 5-like
 310
 0.94
chr2_145408788_145408939 0.38 ZEB2
 zinc finger E-box binding homeobox 2
 130242
 0.06
chr16_54431828_54431986 0.38 IRX3
 iroquois homeobox 3
 111232
 0.07
chr1_244394727_244395045 0.38 C1orf100
 chromosome 1 open reading frame 100
 121051
 0.05
chr17_13502306_13502495 0.37 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
 2844
 0.36
chr3_185482197_185482362 0.37 ENSG00000265470
 .
 3413
 0.28
chr2_135812118_135812269 0.37 RAB3GAP1
 RAB3 GTPase activating protein subunit 1 (catalytic)
 2324
 0.27
chr2_192111060_192111278 0.37 MYO1B
 myosin IB
 160
 0.97
chr9_107968732_107968883 0.36 SLC44A1
 solute carrier family 44 (choline transporter), member 1
 38096
 0.21
chr8_141248134_141248335 0.36 TRAPPC9
 trafficking protein particle complex 9
 212795
 0.02
chr10_9751707_9751888 0.36 ENSG00000200849
 .
 522777
 0.0
chr4_184021000_184021241 0.36 WWC2
 WW and C2 domain containing 2
 475
 0.85
chr9_94245349_94245513 0.36 NFIL3
 nuclear factor, interleukin 3 regulated
 59287
 0.15
chrX_139584851_139585024 0.36 SOX3
 SRY (sex determining region Y)-box 3
 2288
 0.43
chr6_27440042_27440937 0.36 ZNF184
 zinc finger protein 184
 29
 0.98
chr3_19232179_19232330 0.36 KCNH8
 potassium voltage-gated channel, subfamily H (eag-related), member 8
 42308
 0.21
chrX_45612401_45612855 0.36 ENSG00000207725
 .
 6098
 0.25
chr4_73184982_73185292 0.35 RP11-373J21.1
3608
 0.39
chr10_77190951_77191328 0.35 RP11-399K21.10
207
 0.95
chr1_1552204_1552355 0.35 MIB2
 mindbomb E3 ubiquitin protein ligase 2
 509
 0.54
chr8_49320680_49320831 0.35 ENSG00000252710
 .
 100165
 0.08
chr3_107280996_107281147 0.34 BBX
 bobby sox homolog (Drosophila)
 36822
 0.23
chr9_110248552_110248703 0.34 KLF4
 Kruppel-like factor 4 (gut)
 2784
 0.3
chr16_80716241_80716392 0.34 ENSG00000265341
 .
 16856
 0.18
chr4_187644173_187644789 0.34 FAT1
 FAT atypical cadherin 1
 528
 0.87
chr20_36780874_36781212 0.34 TGM2
 transglutaminase 2
 12629
 0.19
chr18_59993646_59993797 0.34 TNFRSF11A
 tumor necrosis factor receptor superfamily, member 11a, NFKB activator
 1173
 0.44
chr3_99356455_99356606 0.33 COL8A1
 collagen, type VIII, alpha 1
 789
 0.74
chr20_57425359_57425924 0.33 GNAS-AS1
 GNAS antisense RNA 1
 292
 0.85
chr6_128897010_128897161 0.33 ENSG00000206982
 .
 8450
 0.2
chr5_106724658_106724809 0.33 EFNA5
 ephrin-A5
 281595
 0.01
chr16_66638822_66640143 0.33 CMTM3
 CKLF-like MARVEL transmembrane domain containing 3
 58
 0.95
chr1_172106062_172106431 0.33 ENSG00000207949
 .
 1801
 0.34
chr9_21683236_21683387 0.33 ENSG00000244230
 .
 16002
 0.23
chr4_187491923_187492195 0.32 MTNR1A
 melatonin receptor 1A
 15338
 0.17
chr9_12776208_12776436 0.32 LURAP1L
 leucine rich adaptor protein 1-like
 1302
 0.47
chr10_18629419_18629841 0.32 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
 36
 0.99
chr5_127872787_127873476 0.32 FBN2
 fibrillin 2
 383
 0.63
chr9_100390326_100390477 0.32 TSTD2
 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
 5456
 0.17
chr19_35605607_35605885 0.32 FXYD3
 FXYD domain containing ion transport regulator 3
 986
 0.35
chr18_10791509_10791660 0.32 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 64
 0.98
chr3_123418520_123418671 0.31 MYLK
 myosin light chain kinase
 7369
 0.19
chr11_122049732_122050124 0.31 ENSG00000207994
 .
 26912
 0.16
chr3_62860670_62860829 0.31 CADPS
 Ca++-dependent secretion activator
 45
 0.99
chr8_26152500_26152651 0.31 PPP2R2A
 protein phosphatase 2, regulatory subunit B, alpha
 1576
 0.5
chr17_10101159_10101987 0.31 GAS7
 growth arrest-specific 7
 295
 0.92
chr3_100711576_100712203 0.31 ABI3BP
 ABI family, member 3 (NESH) binding protein
 408
 0.89
chr4_124476505_124476726 0.31 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 155492
 0.04
chr17_60173604_60173902 0.31 ENSG00000207123
 .
 25928
 0.16
chr10_35645565_35645754 0.31 CCNY
 cyclin Y
 19857
 0.19
chr2_23840040_23840191 0.30 KLHL29
 kelch-like family member 29
 25147
 0.25
chr14_70059777_70059928 0.30 KIAA0247
 KIAA0247
 18461
 0.2
chr2_70528224_70529180 0.30 AC022201.5
119
 0.81
chr2_173330084_173330561 0.30 AC078883.3
418
 0.83
chr5_72411007_72411158 0.30 TMEM171
 transmembrane protein 171
 5037
 0.19
chr1_155616210_155616471 0.30 YY1AP1
 YY1 associated protein 1
 30122
 0.11
chr10_3849010_3849161 0.30 KLF6
 Kruppel-like factor 6
 21612
 0.22
chr16_67896952_67897145 0.29 EDC4
 enhancer of mRNA decapping 4
 9878
 0.08
chr18_74843262_74844680 0.29 MBP
 myelin basic protein
 331
 0.94
chr2_165811625_165811865 0.29 SLC38A11
 solute carrier family 38, member 11
 11
 0.98
chr7_119913514_119913995 0.29 KCND2
 potassium voltage-gated channel, Shal-related subfamily, member 2
 32
 0.99
chr4_20256931_20257082 0.29 SLIT2
 slit homolog 2 (Drosophila)
 463
 0.9
chr18_76746162_76746313 0.29 SALL3
 spalt-like transcription factor 3
 5445
 0.31
chr13_95619763_95620412 0.29 ENSG00000252335
 .
 51402
 0.18
chr17_68165729_68165994 0.29 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 185
 0.66
chr1_38059421_38059572 0.28 GNL2
 guanine nucleotide binding protein-like 2 (nucleolar)
 2026
 0.26
chr14_69727713_69728275 0.28 GALNT16
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
 986
 0.63
chrX_5651570_5651721 0.28 ENSG00000201660
 .
 323482
 0.01
chr17_40162554_40162705 0.28 DNAJC7
 DnaJ (Hsp40) homolog, subfamily C, member 7
 664
 0.41
chr16_4349380_4349548 0.28 GLIS2
 GLIS family zinc finger 2
 15298
 0.13
chr11_64002356_64003048 0.27 VEGFB
 vascular endothelial growth factor B
 410
 0.51
chr11_63581191_63582006 0.27 C11orf84
 chromosome 11 open reading frame 84
 738
 0.6
chr17_80354838_80354989 0.27 RP13-20L14.4
4345
 0.1
chr21_45123118_45123419 0.27 PDXK
 pyridoxal (pyridoxine, vitamin B6) kinase
 15707
 0.17
chr3_10487191_10487342 0.27 ATP2B2
 ATPase, Ca++ transporting, plasma membrane 2
 4031
 0.22
chr5_128796123_128796371 0.27 ADAMTS19-AS1
 ADAMTS19 antisense RNA 1
 135
 0.71
chr18_56888364_56888553 0.27 GRP
 gastrin-releasing peptide
 960
 0.63
chr11_7273101_7273359 0.27 SYT9
 synaptotagmin IX
 49
 0.98
chr16_9204891_9205042 0.27 RP11-473I1.10
3868
 0.18
chr14_105886805_105887920 0.26 MTA1
 metastasis associated 1
 1087
 0.31
chr10_24497729_24498381 0.26 KIAA1217
 KIAA1217
 38
 0.99
chr19_19574756_19575086 0.26 GATAD2A
 GATA zinc finger domain containing 2A
 570
 0.67
chr11_61597292_61597443 0.26 FADS1
 fatty acid desaturase 1
 577
 0.57
chr12_21652771_21652922 0.26 RECQL
 RecQ protein-like (DNA helicase Q1-like)
 1639
 0.29
chr6_1873132_1873283 0.26 FOXC1
 forkhead box C1
 262526
 0.02
chr15_62737317_62737509 0.26 TLN2
 talin 2
 116151
 0.06
chr15_57508769_57508920 0.25 TCF12
 transcription factor 12
 2784
 0.37
chr4_126311427_126311944 0.25 FAT4
 FAT atypical cadherin 4
 3406
 0.33
chr17_66596046_66596347 0.25 FAM20A
 family with sequence similarity 20, member A
 1334
 0.52
chr5_151098113_151098265 0.25 ENSG00000222102
 .
 14050
 0.14
chr12_2340763_2340914 0.25 CACNA1C-AS4
 CACNA1C antisense RNA 4
 8193
 0.25
chr3_27707961_27708112 0.25 EOMES
 eomesodermin
 55767
 0.15
chr1_67029534_67029780 0.25 SGIP1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 29692
 0.2
chr14_92968443_92968594 0.25 RIN3
 Ras and Rab interactor 3
 11600
 0.27
chr21_46825742_46826418 0.25 COL18A1
 collagen, type XVIII, alpha 1
 1028
 0.47
chr6_5941079_5941352 0.24 ENSG00000239472
 .
 22138
 0.24
chr8_114446989_114447172 0.24 CSMD3
 CUB and Sushi multiple domains 3
 2032
 0.42
chr18_47087818_47088752 0.24 LIPG
 lipase, endothelial
 116
 0.96
chr20_2114530_2114681 0.24 ENSG00000263452
 .
 23322
 0.19
chr16_12896672_12896922 0.24 CPPED1
 calcineurin-like phosphoesterase domain containing 1
 911
 0.59
chr19_408624_409082 0.24 C2CD4C
 C2 calcium-dependent domain containing 4C
 286
 0.86
chr14_23775554_23775975 0.24 BCL2L2
 BCL2-like 2
 207
 0.54
chr10_17104740_17104895 0.24 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 65019
 0.12
chr17_62675596_62675747 0.24 SMURF2
 SMAD specific E3 ubiquitin protein ligase 2
 17485
 0.2
chr4_157893196_157893594 0.24 PDGFC
 platelet derived growth factor C
 849
 0.66
chr9_94586642_94586793 0.24 ROR2
 receptor tyrosine kinase-like orphan receptor 2
 124445
 0.06
chr7_93943307_93943458 0.24 COL1A2
 collagen, type I, alpha 2
 80491
 0.11
chr5_58858854_58859005 0.24 PDE4D
 phosphodiesterase 4D, cAMP-specific
 23290
 0.28
chr1_24645756_24645907 0.23 GRHL3
 grainyhead-like 3 (Drosophila)
 19
 0.97
chr4_74316335_74316542 0.23 AFP
 alpha-fetoprotein
 14474
 0.2
chr3_175388674_175388825 0.23 ENSG00000201648
 .
 61482
 0.12
chr13_96742947_96743243 0.23 HS6ST3
 heparan sulfate 6-O-sulfotransferase 3
 2
 0.99
chr18_67955480_67955943 0.23 SOCS6
 suppressor of cytokine signaling 6
 426
 0.88
chr1_243518007_243518236 0.23 ENSG00000265201
 .
 8643
 0.26
chr17_55945252_55945551 0.23 CUEDC1
 CUE domain containing 1
 625
 0.71
chr1_15527398_15527585 0.23 C1orf195
 chromosome 1 open reading frame 195
 29678
 0.16
chr5_78053562_78053713 0.23 LHFPL2
 lipoma HMGIC fusion partner-like 2
 108989
 0.07
chr9_16425913_16426064 0.23 BNC2
 basonuclin 2
 10382
 0.27
chr8_62646329_62646480 0.23 ENSG00000264408
 .
 19057
 0.22
chr17_74696523_74696739 0.23 ENSG00000212418
 .
 3178
 0.11
chr12_78429661_78429970 0.23 RP11-136F16.1
55702
 0.16
chr12_75784171_75784441 0.23 CAPS2
 calcyphosine 2
 375
 0.6
chr5_174115741_174115892 0.23 MSX2
 msh homeobox 2
 35720
 0.21
chr18_56888101_56888263 0.23 GRP
 gastrin-releasing peptide
 684
 0.75
chr4_141348226_141349120 0.23 CLGN
 calmegin
 91
 0.97
chrX_130897762_130897913 0.23 ENSG00000200587
 .
 175147
 0.03
chr16_50401597_50402736 0.23 RP11-21B23.1
325
 0.64
chr10_33630285_33630504 0.23 NRP1
 neuropilin 1
 5204
 0.3
chr5_39102785_39103048 0.23 AC008964.1
2442
 0.36
chr12_71113512_71113735 0.23 PTPRR
 protein tyrosine phosphatase, receptor type, R
 34750
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.2 0.7 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.6 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.3 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.4 GO:0006183 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.9 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0060433 bronchus development(GO:0060433)
0.0 0.0 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.2 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.3 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.5 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0001714 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.4 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.3 GO:0001508 action potential(GO:0001508)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.5 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1 0.4 GO:0043218 compact myelin(GO:0043218)
0.1 0.4 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.0 GO:0043205 fibril(GO:0043205)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.0 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.6 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.2 GO:0030172 troponin C binding(GO:0030172)
0.1 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.1 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12