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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for SMAD2

Z-value: 2.02

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Transcription factors associated with SMAD2

Gene Symbol	Gene ID	Gene Info
SMAD2 Ensembl NCBI GeneCards UniProt	ENSG00000175387.11	SMAD family member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr18_45455773_45456559	SMAD2	567	0.830830	0.63	6.9e-02	Click!
chr18_45456637_45456851	SMAD2	11	0.985878	0.63	7.1e-02	Click!
chr18_45457184_45457514	SMAD2	123	0.976838	0.59	9.4e-02	Click!
chr18_45457756_45458282	SMAD2	504	0.858219	0.41	2.7e-01	Click!
chr18_45494721_45494993	SMAD2	37342	0.189556	0.40	2.9e-01	Click!

Activity of the SMAD2 motif across conditions

Conditions sorted by the z-value of the SMAD2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_49207991_49208212	0.76	CACNB3	calcium channel, voltage-dependent, beta 3 subunit	133	0.92
chr4_153273504_153273905	0.75	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	419	0.87
chr1_9354160_9354311	0.71	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	352	0.88
chr13_38444003_38444421	0.64	TRPC4	transient receptor potential cation channel, subfamily C, member 4	273	0.94
chr3_112355518_112355669	0.64	CCDC80	coiled-coil domain containing 80	1351	0.52
chr19_7953693_7954073	0.63	LRRC8E	leucine rich repeat containing 8 family, member E	447	0.57
chr22_46477251_46477772	0.63	FLJ27365	hsa-mir-4763	1319	0.27
chrX_90689803_90690049	0.63	PABPC5-AS1	PABPC5 antisense RNA 1	72	0.54
chr22_22109080_22109472	0.60	YPEL1	yippee-like 1 (Drosophila)	19153	0.12
chr7_116312981_116313724	0.59	MET	met proto-oncogene	893	0.68
chr11_47431074_47431348	0.59	SLC39A13	solute carrier family 39 (zinc transporter), member 13	69	0.85
chr11_118490674_118490871	0.56	PHLDB1	pleckstrin homology-like domain, family B, member 1	12414	0.11
chr10_72432567_72432920	0.55	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	184	0.96
chrX_65857892_65858837	0.55	EDA2R	ectodysplasin A2 receptor	519	0.86
chr15_40632587_40633009	0.54	C15orf52	chromosome 15 open reading frame 52	370	0.7
chr9_112543013_112543264	0.54	AKAP2	A kinase (PRKA) anchor protein 2	369	0.36
chr5_123121441_123121770	0.52	CSNK1G3	casein kinase 1, gamma 3	197486	0.03
chr22_50698815_50699396	0.52	MAPK12	mitogen-activated protein kinase 12	632	0.49
chr17_15166292_15166618	0.51	PMP22	peripheral myelin protein 22	549	0.68
chr7_22767101_22767320	0.50	AC073072.5		29	0.85
chr3_46607842_46608130	0.50	LRRC2	leucine rich repeat containing 2	54	0.96
chr8_124171100_124171251	0.48	FAM83A	family with sequence similarity 83, member A	20112	0.11
chr11_117070436_117070728	0.47	TAGLN	transgelin	389	0.8
chr10_72431780_72432013	0.46	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	663	0.78
chr21_47517524_47517733	0.46	AP001471.1		184	0.71
chrX_122319080_122319302	0.46	GRIA3	glutamate receptor, ionotropic, AMPA 3	426	0.92
chr22_31478200_31478372	0.45	SMTN	smoothelin	185	0.88
chr14_24868095_24868308	0.45	NYNRIN	NYN domain and retroviral integrase containing	209	0.87
chr17_38601617_38601849	0.44	IGFBP4	insulin-like growth factor binding protein 4	2020	0.24
chr5_92940034_92940231	0.44	ENSG00000251725	.	16362	0.19
chr17_15554007_15555167	0.44	RP11-640I15.1		317	0.52
chr19_11466484_11467017	0.44	DKFZP761J1410	Lipid phosphate phosphatase-related protein type 2	576	0.52
chr7_73095827_73095978	0.44	DNAJC30	DnaJ (Hsp40) homolog, subfamily C, member 30	1881	0.19
chr2_159887379_159887661	0.43	ENSG00000202029	.	3866	0.3
chr13_102105024_102105412	0.43	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	200	0.96
chr12_54623683_54623971	0.43	ENSG00000265371	.	1433	0.25
chr3_44040787_44041403	0.43	ENSG00000252980	.	71484	0.12
chr5_151066115_151066360	0.43	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	287	0.88
chr16_4000635_4001034	0.43	RP11-462G12.1		389	0.84
chr11_1893200_1893351	0.42	LSP1	lymphocyte-specific protein 1	1159	0.31
chr16_70719186_70719575	0.42	MTSS1L	metastasis suppressor 1-like	589	0.67
chr1_8083857_8084201	0.42	ERRFI1	ERBB receptor feedback inhibitor 1	2314	0.32
chr17_74684492_74684746	0.42	MXRA7	matrix-remodelling associated 7	168	0.89
chr10_111765795_111766267	0.42	ADD3	adducin 3 (gamma)	469	0.79
chr2_198538534_198538708	0.42	RFTN2	raftlin family member 2	2098	0.31
chr13_30608189_30608424	0.42	LINC00572	long intergenic non-protein coding RNA 572	107518	0.07
chr10_49812568_49813319	0.42	ARHGAP22	Rho GTPase activating protein 22	54	0.98
chr19_1361001_1361194	0.41	MUM1	melanoma associated antigen (mutated) 1	4734	0.1
chr1_157964321_157964712	0.41	KIRREL	kin of IRRE like (Drosophila)	1081	0.56
chr5_2752991_2753357	0.41	C5orf38	chromosome 5 open reading frame 38	795	0.6
chr2_201173004_201173187	0.41	SPATS2L	spermatogenesis associated, serine-rich 2-like	578	0.82
chr16_14280583_14281066	0.40	MKL2	MKL/myocardin-like 2	52	0.98
chr7_137027775_137027995	0.40	PTN	pleiotrophin	635	0.81
chr1_230220240_230220415	0.40	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	17309	0.23
chr16_54320248_54320703	0.40	IRX3	iroquois homeobox 3	200	0.96
chr11_125365710_125366094	0.40	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	116	0.91
chr17_21477031_21477413	0.40	ENSG00000216100	.	3862	0.25
chr9_34990286_34990475	0.39	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	117	0.95
chr17_19282567_19282778	0.39	MAPK7	mitogen-activated protein kinase 7	608	0.5
chr1_160176245_160176481	0.39	PEA15	phosphoprotein enriched in astrocytes 15	1152	0.24
chr18_55470700_55470927	0.39	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1	486	0.85
chr2_33359781_33360142	0.39	LTBP1	latent transforming growth factor beta binding protein 1	237	0.96
chr19_13135354_13135619	0.39	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	45	0.95
chr22_47486867_47487445	0.39	ENSG00000221672	.	243353	0.02
chr1_46871948_46872121	0.39	FAAH	fatty acid amide hydrolase	12097	0.17
chr15_75940728_75940941	0.39	IMP3	IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)	213	0.75
chr2_191442812_191442963	0.38	ENSG00000251935	.	24681	0.16
chr1_20810827_20811093	0.38	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	1753	0.37
chr1_153599240_153599451	0.38	S100A13	S100 calcium binding protein A13	179	0.83
chr19_56091220_56091371	0.38	ZNF579	zinc finger protein 579	892	0.35
chr18_56246514_56246665	0.38	ENSG00000252284	.	21274	0.14
chr12_124870000_124870249	0.37	NCOR2	nuclear receptor corepressor 2	3246	0.35
chr20_47961894_47962163	0.37	ENSG00000212304	.	64808	0.08
chr9_19493377_19493724	0.37	RP11-363E7.4		40343	0.16
chr11_122311553_122311819	0.37	ENSG00000252776	.	8232	0.23
chr19_55885565_55885716	0.37	TMEM190	transmembrane protein 190	2564	0.1
chr9_707807_708064	0.37	KANK1	KN motif and ankyrin repeat domains 1	1046	0.59
chr2_676152_676450	0.37	TMEM18	transmembrane protein 18	403	0.72
chr1_42383823_42384248	0.37	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	134	0.98
chr16_73094273_73094424	0.37	ZFHX3	zinc finger homeobox 3	751	0.72
chr10_133793290_133793613	0.36	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	1976	0.41
chr9_116328174_116328466	0.36	RGS3	regulator of G-protein signaling 3	959	0.62
chr9_124506702_124506934	0.36	DAB2IP	DAB2 interacting protein	1754	0.47
chr2_158113918_158114875	0.36	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	286	0.93
chr15_96880233_96880461	0.36	ENSG00000222651	.	3857	0.18
chr19_44007322_44007473	0.36	PHLDB3	pleckstrin homology-like domain, family B, member 3	1169	0.34
chr16_86604479_86604706	0.36	RP11-463O9.5		3225	0.19
chr2_45241467_45241680	0.36	SIX2	SIX homeobox 2	5004	0.3
chr18_57364747_57365208	0.36	CCBE1	collagen and calcium binding EGF domains 1	365	0.8
chr1_170555852_170556032	0.35	RP11-576I22.2		54154	0.13
chr2_1609444_1609644	0.35	AC144450.1		14341	0.27
chr15_96878465_96878729	0.35	ENSG00000222651	.	2107	0.24
chr3_43789681_43789832	0.35	ABHD5	abhydrolase domain containing 5	36557	0.2
chr9_116327390_116327681	0.35	RGS3	regulator of G-protein signaling 3	174	0.96
chr15_71408170_71408759	0.35	CT62	cancer/testis antigen 62	631	0.77
chr2_101436314_101436465	0.35	NPAS2	neuronal PAS domain protein 2	225	0.94
chr5_3596833_3597150	0.35	IRX1	iroquois homeobox 1	823	0.68
chr7_45128042_45128214	0.35	NACAD	NAC alpha domain containing	385	0.78
chr7_83823819_83824349	0.35	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	133	0.98
chr6_169653425_169653684	0.35	THBS2	thrombospondin 2	585	0.83
chr7_19155713_19156221	0.34	TWIST1	twist family bHLH transcription factor 1	1328	0.36
chr11_35641402_35641625	0.34	FJX1	four jointed box 1 (Drosophila)	1778	0.42
chr19_13112715_13112989	0.34	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	6200	0.09
chr14_76102618_76102870	0.33	FLVCR2	feline leukemia virus subgroup C cellular receptor family, member 2	3791	0.2
chr8_37555995_37556200	0.33	ZNF703	zinc finger protein 703	2828	0.18
chr1_9258565_9258855	0.33	H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	36124	0.14
chr3_45686682_45686873	0.33	LIMD1-AS1	LIMD1 antisense RNA 1	43597	0.12
chr6_139013214_139013480	0.33	RP11-390P2.4		338	0.5
chr2_133428086_133428391	0.33	LYPD1	LY6/PLAUR domain containing 1	460	0.85
chr4_66534785_66535387	0.33	EPHA5	EPH receptor A5	567	0.87
chrX_48434266_48434493	0.33	RBM3	RNA binding motif (RNP1, RRM) protein 3	92	0.92
chr1_170634990_170635141	0.33	PRRX1	paired related homeobox 1	1987	0.46
chr5_158488627_158488879	0.33	EBF1	early B-cell factor 1	37948	0.17
chr1_209957028_209957179	0.33	C1orf74	chromosome 1 open reading frame 74	801	0.53
chr15_81072797_81073004	0.33	KIAA1199	KIAA1199	1188	0.54
chr12_13325747_13326012	0.32	EMP1	epithelial membrane protein 1	23771	0.21
chr17_66755661_66755820	0.32	ENSG00000263690	.	6960	0.3
chr11_72423916_72424142	0.32	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	167	0.92
chr9_3863343_3863607	0.32	RP11-252M18.3		12109	0.25
chr12_20523094_20523245	0.32	RP11-284H19.1		27	0.96
chr16_70748853_70749053	0.32	VAC14	Vac14 homolog (S. cerevisiae)	14805	0.14
chr20_49271747_49272018	0.32	RP4-530I15.6		2143	0.26
chr15_61521533_61521829	0.32	RORA	RAR-related orphan receptor A	163	0.96
chr7_121513003_121513376	0.32	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	46	0.99
chr22_44982741_44982930	0.32	PRR5	proline rich 5 (renal)	81758	0.09
chrX_122318697_122319049	0.32	GRIA3	glutamate receptor, ionotropic, AMPA 3	108	0.98
chr14_96505776_96506430	0.32	C14orf132	chromosome 14 open reading frame 132	442	0.88
chr22_37823475_37823785	0.32	ELFN2	extracellular leucine-rich repeat and fibronectin type III domain containing 2	125	0.53
chr8_12989314_12989523	0.32	DLC1	deleted in liver cancer 1	1565	0.46
chr4_77561461_77561612	0.31	AC107072.2		2760	0.3
chr1_16087111_16087637	0.31	FBLIM1	filamin binding LIM protein 1	2082	0.2
chr6_35185209_35185407	0.31	SCUBE3	signal peptide, CUB domain, EGF-like 3	3112	0.26
chr19_15217671_15218041	0.31	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	358	0.79
chr1_218519662_218519927	0.31	TGFB2	transforming growth factor, beta 2	217	0.86
chr20_35491527_35491682	0.31	SOGA1	suppressor of glucose, autophagy associated 1	485	0.77
chr16_2209005_2209678	0.31	TRAF7	TNF receptor-associated factor 7, E3 ubiquitin protein ligase	3575	0.07
chr14_53301814_53302501	0.31	FERMT2	fermitin family member 2	29082	0.15
chr6_137113528_137113679	0.31	MAP3K5	mitogen-activated protein kinase kinase kinase 5	53	0.98
chr1_162603783_162603934	0.30	DDR2	discoidin domain receptor tyrosine kinase 2	1598	0.41
chrX_28604967_28605213	0.30	IL1RAPL1	interleukin 1 receptor accessory protein-like 1	426	0.92
chr22_46474299_46474631	0.30	FLJ27365	hsa-mir-4763	1727	0.2
chr3_152553238_152553744	0.30	P2RY1	purinergic receptor P2Y, G-protein coupled, 1	755	0.8
chr9_98412715_98412927	0.30	DKFZP434H0512	Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512	121784	0.05
chr9_129884936_129885087	0.30	ANGPTL2	angiopoietin-like 2	98	0.98
chr12_117297823_117297979	0.30	HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	20992	0.2
chr20_56706861_56707272	0.30	C20orf85	chromosome 20 open reading frame 85	18894	0.21
chr5_139030660_139030811	0.30	CXXC5	CXXC finger protein 5	161	0.96
chr19_3368940_3369091	0.30	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	2431	0.28
chr20_10562806_10562957	0.30	JAG1	jagged 1	80273	0.1
chr1_148930416_148930622	0.30	ENSG00000222854	.	17137	0.25
chr3_47051058_47051537	0.30	NBEAL2	neurobeachin-like 2	4526	0.22
chr6_2397104_2397255	0.30	ENSG00000266252	.	12690	0.3
chr2_230135388_230135942	0.30	PID1	phosphotyrosine interaction domain containing 1	316	0.93
chr7_94025506_94025990	0.29	COL1A2	collagen, type I, alpha 2	1875	0.46
chr6_82854353_82854866	0.29	ENSG00000223044	.	65548	0.14
chr20_35203812_35203967	0.29	TGIF2	TGFB-induced factor homeobox 2	814	0.36
chr12_54403531_54403974	0.29	HOXC8	homeobox C8	920	0.28
chr6_169652381_169652976	0.29	THBS2	thrombospondin 2	432	0.89
chr16_82660458_82660609	0.29	CDH13	cadherin 13	37	0.99
chr2_66659997_66660626	0.29	MEIS1-AS3	MEIS1 antisense RNA 3	291	0.87
chr22_46470676_46471172	0.29	RP6-109B7.4		5153	0.11
chr19_13510256_13510474	0.29	ENSG00000252177	.	23538	0.21
chr7_140016131_140016502	0.29	SLC37A3	solute carrier family 37, member 3	26973	0.14
chr11_62311643_62311985	0.29	AHNAK	AHNAK nucleoprotein	1321	0.22
chr10_13200223_13200374	0.29	MCM10	minichromosome maintenance complex component 10	3256	0.25
chr8_37401810_37402110	0.29	RP11-150O12.6		27421	0.21
chr11_88135716_88135867	0.29	CTSC	cathepsin C	64836	0.13
chr6_43242790_43242944	0.29	SLC22A7	solute carrier family 22 (organic anion transporter), member 7	22869	0.11
chr19_55881999_55882196	0.29	IL11	interleukin 11	266	0.76
chr1_13910269_13910760	0.29	PDPN	podoplanin	74	0.97
chr20_56283633_56283861	0.28	PMEPA1	prostate transmembrane protein, androgen induced 1	1069	0.63
chr1_34629040_34629587	0.28	CSMD2	CUB and Sushi multiple domains 2	1562	0.36
chr7_72756827_72757013	0.28	ENSG00000206709	.	3717	0.17
chr1_6674083_6674241	0.28	PHF13	PHD finger protein 13	417	0.47
chr1_149908531_149908774	0.28	MTMR11	myotubularin related protein 11	139	0.92
chr20_44410549_44410700	0.28	ENSG00000221046	.	3287	0.12
chr6_152957367_152957953	0.28	SYNE1	spectrin repeat containing, nuclear envelope 1	326	0.92
chr4_77869335_77869486	0.28	SEPT11	septin 11	1446	0.48
chr12_53440601_53440838	0.28	RP11-983P16.4		24	0.5
chr14_52117494_52117667	0.28	FRMD6	FERM domain containing 6	996	0.57
chr5_167646669_167646982	0.28	CTB-178M22.2		12537	0.22
chr12_28122408_28123172	0.28	PTHLH	parathyroid hormone-like hormone	190	0.95
chr12_16501441_16501633	0.28	MGST1	microsomal glutathione S-transferase 1	806	0.73
chr17_45331851_45332126	0.28	ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	725	0.57
chr9_22008460_22008654	0.28	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	395	0.82
chr9_708078_708584	0.28	KANK1	KN motif and ankyrin repeat domains 1	1442	0.47
chr3_73672725_73672876	0.28	PDZRN3-AS1	PDZRN3 antisense RNA 1	81	0.96
chr11_85429273_85429899	0.28	SYTL2	synaptotagmin-like 2	55	0.97
chr17_5973941_5974097	0.28	WSCD1	WSC domain containing 1	85	0.98
chr3_49169788_49170138	0.28	LAMB2	laminin, beta 2 (laminin S)	490	0.65
chr6_6737313_6737878	0.28	LY86-AS1	LY86 antisense RNA 1	114591	0.06
chr6_114179524_114179876	0.27	MARCKS	myristoylated alanine-rich protein kinase C substrate	1159	0.5
chr1_51730484_51730663	0.27	RP11-296A18.6		1173	0.41
chr6_3809409_3809569	0.27	RP11-420L9.4		22678	0.18
chr19_35522133_35522284	0.27	SCN1B	sodium channel, voltage-gated, type I, beta subunit	483	0.65
chr12_54388704_54389082	0.27	HOXC6	homeobox C6	165	0.65
chr11_12696098_12696447	0.27	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	108	0.98
chr1_39877068_39877317	0.27	KIAA0754	KIAA0754	1041	0.5
chr5_55615599_55615750	0.27	ENSG00000210678	.	22158	0.2
chr4_99578140_99578845	0.27	TSPAN5	tetraspanin 5	294	0.89

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.7	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.2	0.6	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.5	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	0.5	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.2	0.5	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.2	0.3	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	1.3	GO:0001945	lymph vessel development(GO:0001945)
0.1	0.6	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.3	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.6	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.6	GO:0032288	myelin assembly(GO:0032288)
0.1	0.3	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.4	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.3	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.3	GO:0045112	integrin biosynthetic process(GO:0045112)
0.1	0.3	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.2	GO:0071504	cellular response to heparin(GO:0071504)
0.1	0.3	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0072205	metanephric collecting duct development(GO:0072205)
0.1	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.3	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.2	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.2	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.1	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1	0.6	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.2	GO:0048539	bone marrow development(GO:0048539)
0.1	0.2	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0071800	podosome assembly(GO:0071800)
0.1	0.8	GO:0035329	hippo signaling(GO:0035329)
0.1	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.3	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.2	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	1.4	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.2	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.8	GO:0042474	middle ear morphogenesis(GO:0042474)
0.1	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.1	0.3	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.1	0.6	GO:0009629	response to gravity(GO:0009629)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.6	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1	0.6	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.1	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.2	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1	0.2	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.2	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.2	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.1	0.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.2	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.1	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.1	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.1	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.1	0.2	GO:0005997	xylulose metabolic process(GO:0005997)
0.1	0.3	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.1	0.2	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.1	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1	0.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	0.1	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	1.3	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.2	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	1.2	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.4	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.7	GO:0045844	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.2	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.0	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.2	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.2	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.4	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.0	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569) rhombomere 4 development(GO:0021570) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.7	GO:0007566	embryo implantation(GO:0007566)
0.0	0.3	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.4	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.2	GO:0032026	response to magnesium ion(GO:0032026)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb(GO:0022028)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0044319	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.0	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0061162	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:1903019	negative regulation of glycoprotein metabolic process(GO:1903019)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.2	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.3	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.4	GO:0035195	gene silencing by miRNA(GO:0035195)
0.0	0.1	GO:0060073	urinary bladder smooth muscle contraction(GO:0014832) micturition(GO:0060073) smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.6	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.3	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.0	GO:0060433	bronchus development(GO:0060433)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0051608	histamine transport(GO:0051608)
0.0	0.2	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.3	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.3	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0048741	skeletal muscle fiber development(GO:0048741)
0.0	0.1	GO:0002090	regulation of receptor internalization(GO:0002090)
0.0	0.2	GO:0001952	regulation of cell-matrix adhesion(GO:0001952)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0046325	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0035067	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0021772	olfactory bulb development(GO:0021772)
0.0	0.0	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.1	GO:0010717	regulation of epithelial to mesenchymal transition(GO:0010717)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.0	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.1	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.3	GO:0042730	fibrinolysis(GO:0042730)
0.0	2.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.5	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.3	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0060487	lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0	0.1	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0032527	retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.0	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0001964	startle response(GO:0001964)
0.0	0.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0042559	folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.3	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.0	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.0	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.4	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.1	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.3	GO:0070509	calcium ion import(GO:0070509)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0006183	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.4	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.4	GO:0001841	neural tube formation(GO:0001841)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.2	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.0	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.0	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0016139	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.0	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.0	0.0	GO:0048241	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.4	GO:0001764	neuron migration(GO:0001764)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.2	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0045823	positive regulation of heart contraction(GO:0045823)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.0	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.2	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.5	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:0001840	neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0	0.1	GO:0032057	negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0030730	sequestering of triglyceride(GO:0030730)
0.0	0.2	GO:0030705	cytoskeleton-dependent intracellular transport(GO:0030705)
0.0	0.0	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.4	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.1	GO:0071398	cellular response to fatty acid(GO:0071398)
0.0	0.4	GO:0000724	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.2	GO:0050773	regulation of dendrite development(GO:0050773)
0.0	0.0	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.2	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
0.0	0.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.0	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0009220	pyrimidine ribonucleotide biosynthetic process(GO:0009220)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.2	GO:0007030	Golgi organization(GO:0007030)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0051789	obsolete response to protein(GO:0051789)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:0002369	T cell cytokine production(GO:0002369) regulation of T cell cytokine production(GO:0002724)
0.0	0.0	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.2	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.0	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.0	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.0	GO:0090311	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.0	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.0	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0021987	cerebral cortex development(GO:0021987)
0.0	0.0	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148)
0.0	0.0	GO:2000573	positive regulation of DNA biosynthetic process(GO:2000573)
0.0	0.0	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.0	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0010922	positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.8	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.3	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.5	GO:0001527	microfibril(GO:0001527)
0.1	0.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	1.9	GO:0034704	calcium channel complex(GO:0034704)
0.1	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.3	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.3	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.2	GO:0032449	CBM complex(GO:0032449)
0.0	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0032059	bleb(GO:0032059)
0.0	0.0	GO:0016460	myosin II complex(GO:0016460)
0.0	0.3	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.8	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0042641	actomyosin(GO:0042641)
0.0	1.1	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.0	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.0	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.4	GO:0071565	nBAF complex(GO:0071565)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.3	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	7.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.0	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.3	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	1.2	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.7	GO:0030018	Z disc(GO:0030018)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	1.3	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.5	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	2.8	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.4	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	1.7	GO:0030425	dendrite(GO:0030425)
0.0	0.1	GO:0030120	vesicle coat(GO:0030120)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.0	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.8	GO:0043292	contractile fiber(GO:0043292)
0.0	0.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.1	GO:0030990	intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	1.0	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.4	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.0	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.0	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.4	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	1.0	GO:0000151	ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.4	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.4	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.9	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.6	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.3	GO:0005113	patched binding(GO:0005113)
0.1	0.3	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.3	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.3	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.2	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.4	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.8	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.9	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.3	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	1.2	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.1	0.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.1	GO:0048185	activin binding(GO:0048185)
0.1	0.4	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.5	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.4	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.2	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.2	GO:0034711	inhibin binding(GO:0034711)
0.1	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.8	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.7	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.8	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	1.1	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.5	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.6	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.8	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.3	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.5	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.2	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.4	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	1.4	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	1.9	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.4	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	1.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0015184	sulfur amino acid transmembrane transporter activity(GO:0000099) L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.4	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.3	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.0	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.0	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.2	GO:0070405	ammonium ion binding(GO:0070405)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	3.1	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	1.2	GO:0008083	growth factor activity(GO:0008083)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.3	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.7	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.0	GO:0003785	actin monomer binding(GO:0003785)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	3.0	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	1.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.0	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.0	PID INSULIN PATHWAY	Insulin Pathway
0.0	1.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	4.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.6	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.7	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.6	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	3.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.1	1.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	0.7	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	2.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	0.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.9	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.0	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.7	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.3	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.0	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.6	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport

Results for SMAD2

Z-value: 2.02

Motif logo

Transcription factors associated with SMAD2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the SMAD2 motif across conditions

Conditions sorted by the z-value of the SMAD2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: