Project

ENCODE: H3K4me3 ChIP-Seq of primary human cells

Navigation

Downloads

Results for SMAD4

Z-value: 2.08

Motif logo

Transcription factors associated with SMAD4

Gene Symbol	Gene ID	Gene Info
SMAD4 Ensembl NCBI GeneCards UniProt	ENSG00000141646.9	SMAD family member 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr18_48571368_48571694	SMAD4	202	0.956317	0.78	1.4e-02	Click!
chr18_48558329_48558480	SMAD4	1821	0.411704	0.74	2.1e-02	Click!
chr18_48580126_48580277	SMAD4	6784	0.247804	0.67	5.0e-02	Click!
chr18_48555753_48556476	SMAD4	130	0.971496	-0.43	2.4e-01	Click!
chr18_48556587_48556782	SMAD4	101	0.976229	-0.21	5.9e-01	Click!

Activity of the SMAD4 motif across conditions

Conditions sorted by the z-value of the SMAD4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_121633_122294	1.38	RHBDF1	rhomboid 5 homolog 1 (Drosophila)	666	0.51
chr1_157964321_157964712	1.14	KIRREL	kin of IRRE like (Drosophila)	1081	0.56
chr1_179110770_179111258	1.09	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	1165	0.52
chr5_131593477_131594185	1.07	PDLIM4	PDZ and LIM domain 4	431	0.81
chr15_96878987_96879612	0.96	ENSG00000222651	.	2809	0.21
chr6_41605286_41606011	0.92	MDFI	MyoD family inhibitor	528	0.74
chr1_157964729_157965124	0.91	KIRREL	kin of IRRE like (Drosophila)	1491	0.45
chr11_94473290_94474384	0.87	RP11-867G2.8		316	0.92
chr13_30168298_30169638	0.85	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	857	0.74
chr20_56283633_56283861	0.84	PMEPA1	prostate transmembrane protein, androgen induced 1	1069	0.63
chr16_2077067_2078193	0.83	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	701	0.35
chr5_151066115_151066360	0.82	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	287	0.88
chr9_130860823_130861938	0.78	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	544	0.57
chr1_2187001_2187152	0.75	SKI	v-ski avian sarcoma viral oncogene homolog	26942	0.11
chr12_13351879_13352395	0.75	EMP1	epithelial membrane protein 1	2417	0.37
chr15_96874865_96875199	0.75	NR2F2	nuclear receptor subfamily 2, group F, member 2	734	0.54
chr14_76842499_76842966	0.75	ENSG00000263880	.	21380	0.18
chr19_3094656_3095580	0.74	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	710	0.53
chr13_96705072_96705326	0.73	UGGT2	UDP-glucose glycoprotein glucosyltransferase 2	438	0.88
chr7_5469244_5469831	0.73	TNRC18	trinucleotide repeat containing 18	4492	0.16
chrX_153601896_153602918	0.72	FLNA	filamin A, alpha	587	0.54
chr5_63461313_63462499	0.72	RNF180	ring finger protein 180	83	0.99
chr12_115889903_115890336	0.71	RP11-116D17.1	HCG2038717; Uncharacterized protein	89302	0.1
chr13_27334023_27334664	0.71	GPR12	G protein-coupled receptor 12	84	0.98
chr11_834351_834871	0.71	CD151	CD151 molecule (Raph blood group)	261	0.74
chr5_83680091_83680703	0.71	CTD-2269F5.1		23	0.71
chr19_55998584_55999113	0.70	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)	923	0.28
chr18_24155058_24155571	0.70	ENSG00000252846	.	11448	0.22
chr7_94025506_94025990	0.70	COL1A2	collagen, type I, alpha 2	1875	0.46
chr6_84139999_84140706	0.69	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	412	0.89
chr3_45052751_45053653	0.68	CLEC3B	C-type lectin domain family 3, member B	14473	0.15
chr12_54391177_54391923	0.68	HOXC-AS2	HOXC cluster antisense RNA 2	981	0.22
chr11_131781926_131782158	0.67	NTM	neurotrimin	680	0.75
chr5_9544374_9544669	0.67	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	1666	0.36
chr10_28957462_28957722	0.64	ENSG00000207483	.	744	0.65
chr1_94130614_94130821	0.64	BCAR3	breast cancer anti-estrogen resistance 3	16209	0.23
chr12_59309288_59309823	0.64	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	1191	0.55
chr6_157187833_157188092	0.64	ARID1B	AT rich interactive domain 1B (SWI1-like)	34545	0.21
chr6_137310724_137311134	0.64	RP11-204P2.3		5378	0.23
chr12_106531293_106531501	0.64	NUAK1	NUAK family, SNF1-like kinase, 1	2414	0.35
chr9_139239711_139240188	0.63	GPSM1	G-protein signaling modulator 1	7560	0.12
chr11_119292436_119293234	0.63	THY1	Thy-1 cell surface antigen	437	0.74
chr3_44040787_44041403	0.63	ENSG00000252980	.	71484	0.12
chr8_119964322_119964783	0.62	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	113	0.98
chr16_31482827_31483290	0.62	TGFB1I1	transforming growth factor beta 1 induced transcript 1	152	0.9
chr9_16864507_16865020	0.62	BNC2	basonuclin 2	5941	0.33
chr9_708078_708584	0.61	KANK1	KN motif and ankyrin repeat domains 1	1442	0.47
chr17_38601617_38601849	0.61	IGFBP4	insulin-like growth factor binding protein 4	2020	0.24
chr1_162666353_162666719	0.61	DDR2	discoidin domain receptor tyrosine kinase 2	64276	0.1
chr20_10651490_10651885	0.61	RP11-103J8.1		1889	0.38
chr22_36232996_36233711	0.60	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2912	0.37
chr1_32168571_32169014	0.60	COL16A1	collagen, type XVI, alpha 1	976	0.48
chr19_42754686_42755478	0.60	ERF	Ets2 repressor factor	489	0.61
chr15_40395062_40395658	0.59	BMF	Bcl2 modifying factor	2927	0.21
chr6_27059721_27060142	0.59	ENSG00000222800	.	17828	0.13
chr6_19838575_19839711	0.59	RP1-167F1.2		168	0.95
chr14_63671002_63671585	0.59	RHOJ	ras homolog family member J	167	0.97
chr19_13135354_13135619	0.59	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	45	0.95
chr5_57754273_57754664	0.58	PLK2	polo-like kinase 2	1619	0.44
chr2_27301899_27302732	0.58	EMILIN1	elastin microfibril interfacer 1	880	0.32
chr17_36903249_36903547	0.58	PCGF2	polycomb group ring finger 2	517	0.51
chrX_48434266_48434493	0.58	RBM3	RNA binding motif (RNP1, RRM) protein 3	92	0.92
chr22_36310772_36312004	0.58	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	23557	0.25
chr5_57751342_57751690	0.58	PLK2	polo-like kinase 2	4571	0.26
chr1_234792376_234792776	0.57	IRF2BP2	interferon regulatory factor 2 binding protein 2	47305	0.14
chr21_32715523_32716836	0.57	TIAM1	T-cell lymphoma invasion and metastasis 1	415	0.91
chr8_36999968_37000340	0.57	KCNU1	potassium channel, subfamily U, member 1	213731	0.02
chr19_38747098_38747353	0.56	PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	6	0.95
chr9_113341179_113342041	0.56	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	213	0.96
chr19_41195138_41195302	0.56	NUMBL	numb homolog (Drosophila)-like	277	0.86
chr1_34629040_34629587	0.56	CSMD2	CUB and Sushi multiple domains 2	1562	0.36
chr9_117879769_117880175	0.56	TNC	tenascin C	506	0.85
chr14_105435453_105435767	0.56	AHNAK2	AHNAK nucleoprotein 2	9084	0.16
chr2_14775112_14775752	0.55	AC011897.1	Uncharacterized protein	217	0.95
chr18_10454899_10455524	0.55	APCDD1	adenomatosis polyposis coli down-regulated 1	232	0.95
chr14_23447268_23447766	0.55	AJUBA	ajuba LIM protein	571	0.5
chr3_181285218_181285513	0.55	SOX2-OT	SOX2 overlapping transcript (non-protein coding)	3856	0.36
chr3_64674138_64674393	0.55	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	589	0.78
chr2_9389435_9389677	0.55	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	42662	0.19
chr13_110972233_110972468	0.55	COL4A2	collagen, type IV, alpha 2	12736	0.21
chr19_45147190_45148055	0.55	PVR	poliovirus receptor	225	0.9
chr10_122837866_122838157	0.55	RP11-95I16.4		197832	0.03
chr6_27637728_27637897	0.54	ENSG00000238648	.	38624	0.13
chr2_33360890_33361153	0.53	LTBP1	latent transforming growth factor beta binding protein 1	1297	0.6
chr18_421335_421729	0.53	RP11-720L2.2		2884	0.33
chr9_113342240_113342458	0.53	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	189	0.96
chr7_140016131_140016502	0.53	SLC37A3	solute carrier family 37, member 3	26973	0.14
chr22_24321651_24321919	0.53	DDT	D-dopachrome tautomerase	234	0.72
chr13_38444003_38444421	0.53	TRPC4	transient receptor potential cation channel, subfamily C, member 4	273	0.94
chr22_46482810_46483184	0.53	FLJ27365	hsa-mir-4763	1114	0.31
chr12_96613281_96613604	0.53	RP11-394J1.2		4309	0.24
chr7_121776912_121777110	0.52	AASS	aminoadipate-semialdehyde synthase	3135	0.34
chr11_120195755_120196855	0.52	TMEM136	transmembrane protein 136	289	0.9
chr3_129323468_129324020	0.52	PLXND1	plexin D1	1917	0.3
chr1_120839623_120840218	0.52	FAM72B	family with sequence similarity 72, member B	508	0.73
chr17_79533386_79533781	0.52	NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	45	0.95
chr17_75316367_75316959	0.52	SEPT9	septin 9	268	0.93
chr2_218715390_218715592	0.52	TNS1	tensin 1	8608	0.27
chr16_54320248_54320703	0.52	IRX3	iroquois homeobox 3	200	0.96
chr22_45900582_45901194	0.51	FBLN1	fibulin 1	1962	0.36
chr22_24303788_24304049	0.51	GSTT2B	glutathione S-transferase theta 2B (gene/pseudogene)	545	0.62
chr1_156098075_156098411	0.51	LMNA	lamin A/C	1649	0.24
chr17_40933254_40933426	0.51	WNK4	WNK lysine deficient protein kinase 4	644	0.49
chr11_94501626_94502525	0.51	AMOTL1	angiomotin like 1	538	0.82
chr3_117715779_117716482	0.51	LSAMP	limbic system-associated membrane protein	35	0.99
chr4_55991312_55991871	0.51	KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	165	0.96
chr1_2125304_2125678	0.51	C1orf86	chromosome 1 open reading frame 86	689	0.55
chr13_40976108_40976619	0.51	ENSG00000252812	.	5214	0.32
chr19_49864989_49865626	0.51	DKKL1	dickkopf-like 1	267	0.51
chr13_110958781_110959436	0.51	COL4A1	collagen, type IV, alpha 1	370	0.6
chr2_167232459_167233133	0.51	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit	293	0.93
chr4_69138068_69138418	0.51	TMPRSS11B	transmembrane protease, serine 11B	26805	0.16
chr4_138045655_138046009	0.51	ENSG00000222526	.	103450	0.09
chrX_90689803_90690049	0.50	PABPC5-AS1	PABPC5 antisense RNA 1	72	0.54
chr17_78008798_78009385	0.50	TBC1D16	TBC1 domain family, member 16	556	0.63
chr5_176047518_176047699	0.50	ENSG00000266329	.	8893	0.11
chr8_22023419_22024083	0.50	BMP1	bone morphogenetic protein 1	951	0.4
chr20_24451000_24451472	0.50	SYNDIG1	synapse differentiation inducing 1	1401	0.6
chr17_29887299_29887674	0.50	ENSG00000207614	.	471	0.69
chr15_40632587_40633009	0.50	C15orf52	chromosome 15 open reading frame 52	370	0.7
chr1_230220240_230220415	0.50	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	17309	0.23
chr5_38844869_38845152	0.50	OSMR	oncostatin M receptor	950	0.68
chr16_75283915_75284066	0.50	BCAR1	breast cancer anti-estrogen resistance 1	126	0.95
chr12_53264048_53264199	0.50	KRT78	keratin 78	21247	0.12
chr13_33858654_33859881	0.49	STARD13	StAR-related lipid transfer (START) domain containing 13	625	0.76
chr6_128812548_128813040	0.49	RP1-86D1.5		8878	0.17
chr3_49170609_49171370	0.49	LAMB2	laminin, beta 2 (laminin S)	438	0.69
chr21_31311288_31312406	0.49	GRIK1	glutamate receptor, ionotropic, kainate 1	3	0.99
chr17_70587270_70588900	0.49	ENSG00000200783	.	72206	0.12
chr11_846113_846544	0.49	TSPAN4	tetraspanin 4	869	0.31
chr5_169404629_169404937	0.49	FAM196B	family with sequence similarity 196, member B	2961	0.34
chr5_52775201_52775957	0.49	FST	follistatin	660	0.81
chr3_99591263_99591414	0.48	FILIP1L	filamin A interacting protein 1-like	3610	0.31
chr19_52193032_52193401	0.48	ENSG00000207550	.	2649	0.13
chr4_186853517_186853755	0.48	ENSG00000239034	.	13601	0.21
chr9_116356768_116357019	0.48	RGS3	regulator of G-protein signaling 3	1127	0.54
chr1_212811256_212811776	0.48	RP11-338C15.5		11403	0.14
chr2_178029177_178029397	0.48	ENSG00000251746	.	25860	0.12
chr11_122050333_122050506	0.48	ENSG00000207994	.	27403	0.16
chr3_44063258_44064101	0.48	ENSG00000252980	.	48900	0.17
chr19_10530586_10531042	0.48	CDC37	cell division cycle 37	17	0.89
chr17_77019963_77021139	0.48	C1QTNF1	C1q and tumor necrosis factor related protein 1	208	0.91
chr22_46035148_46035374	0.48	ENSG00000251985	.	14749	0.18
chr21_35925267_35925598	0.47	RCAN1	regulator of calcineurin 1	7045	0.23
chr9_97401149_97402104	0.47	FBP1	fructose-1,6-bisphosphatase 1	163	0.96
chr7_130590481_130590772	0.47	ENSG00000226380	.	28328	0.21
chrX_17394576_17394820	0.47	NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)	1155	0.54
chr5_131594297_131594770	0.47	PDLIM4	PDZ and LIM domain 4	1133	0.45
chr2_223858757_223859103	0.47	KCNE4	potassium voltage-gated channel, Isk-related family, member 4	57602	0.12
chr10_119301594_119301816	0.47	EMX2OS	EMX2 opposite strand/antisense RNA	125	0.68
chr8_11331901_11332173	0.47	FAM167A	family with sequence similarity 167, member A	6934	0.16
chr3_55519561_55519953	0.47	WNT5A	wingless-type MMTV integration site family, member 5A	1574	0.4
chr19_54984470_54984783	0.47	CDC42EP5	CDC42 effector protein (Rho GTPase binding) 5	215	0.86
chr10_24544335_24544573	0.47	KIAA1217	KIAA1217	197	0.96
chr17_79368504_79368935	0.46	RP11-1055B8.6	Uncharacterized protein	556	0.64
chr14_65228831_65229071	0.46	SPTB	spectrin, beta, erythrocytic	20317	0.18
chr19_1361001_1361194	0.46	MUM1	melanoma associated antigen (mutated) 1	4734	0.1
chr22_18049670_18050213	0.46	SLC25A18	solute carrier family 25 (glutamate carrier), member 18	6791	0.19
chr12_124870000_124870249	0.46	NCOR2	nuclear receptor corepressor 2	3246	0.35
chr2_218843405_218844030	0.46	TNS1	tensin 1	60	0.79
chr7_47367439_47367819	0.46	TNS3	tensin 3	47713	0.2
chr16_70719186_70719575	0.46	MTSS1L	metastasis suppressor 1-like	589	0.67
chr1_32170118_32170299	0.46	COL16A1	collagen, type XVI, alpha 1	288	0.88
chr7_47610970_47611742	0.46	TNS3	tensin 3	9873	0.29
chr22_41957409_41957697	0.46	CSDC2	cold shock domain containing C2, RNA binding	786	0.54
chr21_28215844_28216573	0.46	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	112	0.98
chr6_42374970_42375191	0.46	ENSG00000221252	.	5054	0.25
chr16_67881079_67882065	0.45	CENPT	centromere protein T	24	0.87
chr10_33622034_33622426	0.45	NRP1	neuropilin 1	1080	0.63
chr7_128471351_128471889	0.45	FLNC	filamin C, gamma	1140	0.39
chr15_72529055_72529849	0.45	PKM	pyruvate kinase, muscle	5288	0.17
chr19_42440673_42440856	0.45	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	13518	0.12
chr15_99846907_99847155	0.45	AC022819.2	Uncharacterized protein	12797	0.18
chr10_29010987_29011704	0.45	ENSG00000201001	.	38387	0.14
chr22_31478200_31478372	0.45	SMTN	smoothelin	185	0.88
chr12_54412522_54412673	0.45	HOXC4	homeobox C4	1882	0.13
chr4_169552961_169553147	0.45	PALLD	palladin, cytoskeletal associated protein	286	0.92
chr4_184908942_184909331	0.44	RP11-739P1.2		305	0.92
chr14_37641366_37641769	0.44	SLC25A21	solute carrier family 25 (mitochondrial oxoadipate carrier), member 21	61	0.88
chr18_12253921_12254616	0.44	CIDEA	cell death-inducing DFFA-like effector a	50	0.98
chr22_50740171_50740441	0.44	PLXNB2	plexin B2	415	0.69
chr2_228028292_228028853	0.44	COL4A4	collagen, type IV, alpha 4	257	0.8
chr4_7632530_7632898	0.44	SORCS2	sortilin-related VPS10 domain containing receptor 2	103293	0.07
chr3_184037306_184037783	0.44	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	1	0.95
chr3_11266982_11267215	0.44	HRH1	histamine receptor H1	619	0.81
chr2_216297601_216297993	0.44	FN1	fibronectin 1	2993	0.27
chr20_60931125_60931499	0.44	RP11-157P1.5		3243	0.15
chr1_153599240_153599451	0.44	S100A13	S100 calcium binding protein A13	179	0.83
chr3_73674636_73674822	0.44	PDZRN3	PDZ domain containing ring finger 3	638	0.7
chr5_140864363_140864795	0.44	PCDHGC4	protocadherin gamma subfamily C, 4	162	0.89
chr20_43729394_43729952	0.44	KCNS1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	77	0.96
chr11_121975812_121976123	0.44	RP11-166D19.1		90	0.96
chr22_30649026_30649248	0.43	LIF	leukemia inhibitory factor	6297	0.11
chr3_9745623_9746706	0.43	CPNE9	copine family member IX	654	0.62
chr20_33759810_33760395	0.43	PROCR	protein C receptor, endothelial	226	0.9
chr16_4366907_4367444	0.43	GLIS2	GLIS family zinc finger 2	2413	0.21
chr19_4061458_4061934	0.43	CTD-2622I13.3		1051	0.37
chr3_98612768_98613177	0.43	DCBLD2	discoidin, CUB and LCCL domain containing 2	7043	0.19
chr16_53086342_53086851	0.43	RP11-467J12.4		189	0.95
chr20_34025363_34025770	0.43	GDF5	growth differentiation factor 5	457	0.71

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.6	2.4	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5	1.5	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.5	1.8	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.4	1.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.4	1.6	GO:0072070	loop of Henle development(GO:0072070)
0.4	1.2	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3	0.3	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.3	1.3	GO:0043589	skin morphogenesis(GO:0043589)
0.3	1.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.3	0.9	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.3	0.9	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.3	0.8	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.3	1.1	GO:0008218	bioluminescence(GO:0008218)
0.3	0.8	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3	0.8	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.3	0.8	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.3	0.5	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2	0.7	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.2	0.7	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.2	0.7	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.7	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.2	1.3	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2	0.8	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2	0.8	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.2	0.8	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	0.8	GO:0070141	response to UV-A(GO:0070141)
0.2	0.8	GO:0060013	righting reflex(GO:0060013)
0.2	0.6	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2	0.4	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.2	0.2	GO:0050923	Roundabout signaling pathway(GO:0035385) regulation of negative chemotaxis(GO:0050923)
0.2	0.4	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.2	0.8	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.2	0.2	GO:0072033	renal vesicle formation(GO:0072033)
0.2	0.4	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.2	0.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.2	0.5	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.2	0.9	GO:0032288	myelin assembly(GO:0032288)
0.2	0.2	GO:0051584	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.2	0.5	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.2	1.0	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.2	0.3	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.2	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	0.8	GO:0021873	forebrain neuroblast division(GO:0021873)
0.2	0.8	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.2	0.5	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.2	1.0	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.2	0.9	GO:0090103	cochlea morphogenesis(GO:0090103)
0.2	0.6	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.2	0.5	GO:0060676	ureteric bud formation(GO:0060676)
0.1	1.6	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.9	GO:0060039	pericardium development(GO:0060039)
0.1	0.6	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.6	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.4	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	0.4	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.3	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.9	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.4	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.4	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.4	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.4	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.4	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	0.1	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	0.6	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.4	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.5	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.6	GO:0090175	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1	0.4	GO:0045112	integrin biosynthetic process(GO:0045112)
0.1	0.2	GO:0001945	lymph vessel development(GO:0001945)
0.1	0.2	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1	0.4	GO:0051451	myoblast migration(GO:0051451)
0.1	0.9	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	2.2	GO:0008038	neuron recognition(GO:0008038)
0.1	0.6	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	0.1	GO:0060913	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214) cardiac cell fate determination(GO:0060913)
0.1	0.1	GO:0001705	ectoderm formation(GO:0001705)
0.1	0.4	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.1	0.5	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.1	0.8	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.6	GO:0021984	adenohypophysis development(GO:0021984)
0.1	0.3	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.9	GO:0009629	response to gravity(GO:0009629)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.5	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.3	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.2	GO:0072044	collecting duct development(GO:0072044)
0.1	1.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1	0.4	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.1	GO:0060438	trachea development(GO:0060438)
0.1	0.5	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.1	0.2	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.7	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.3	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.4	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	1.2	GO:0035329	hippo signaling(GO:0035329)
0.1	0.4	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	0.2	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1	0.4	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1	0.4	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	1.2	GO:0098876	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.1	0.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.4	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.3	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	0.3	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.4	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.4	GO:0048539	bone marrow development(GO:0048539)
0.1	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.1	0.4	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.1	1.5	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.2	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.1	0.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.5	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.4	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.8	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.1	0.1	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1	0.1	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.2	GO:0022601	menstrual cycle phase(GO:0022601)
0.1	0.6	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.1	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.1	1.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.3	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.6	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.1	GO:0060437	lung growth(GO:0060437)
0.1	0.3	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.1	GO:0060592	mammary gland formation(GO:0060592)
0.1	0.8	GO:0007520	myoblast fusion(GO:0007520)
0.1	1.0	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.1	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.1	0.1	GO:0060439	trachea morphogenesis(GO:0060439)
0.1	0.4	GO:0043113	receptor clustering(GO:0043113)
0.1	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	2.0	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.3	GO:0051014	actin filament severing(GO:0051014)
0.1	0.8	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.3	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.1	0.3	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.1	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.1	GO:0051955	regulation of amino acid transport(GO:0051955)
0.1	0.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.7	GO:0008347	glial cell migration(GO:0008347)
0.1	0.1	GO:0055057	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.2	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.1	0.6	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.1	0.4	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	1.6	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.1	0.6	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.5	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.1	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.5	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.1	0.1	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1	0.3	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.8	GO:0042474	middle ear morphogenesis(GO:0042474)
0.1	0.2	GO:0044557	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.1	0.2	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1	0.2	GO:0001706	endoderm formation(GO:0001706)
0.1	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.1	GO:0010193	response to ozone(GO:0010193)
0.1	1.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.1	GO:0032222	regulation of synaptic transmission, cholinergic(GO:0032222)
0.1	0.1	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.1	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	9.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	0.1	GO:0085029	extracellular matrix assembly(GO:0085029)
0.1	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.2	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.1	0.5	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.5	GO:0031050	dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.1	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.1	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.1	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.1	0.5	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	0.1	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.1	0.1	GO:0090102	cochlea development(GO:0090102)
0.1	0.5	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.3	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1	0.2	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.3	GO:0016246	RNA interference(GO:0016246)
0.1	0.5	GO:0021983	pituitary gland development(GO:0021983)
0.1	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.8	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.1	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.1	0.4	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	1.4	GO:0042633	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.1	0.1	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.1	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.6	GO:0048566	embryonic digestive tract development(GO:0048566)
0.1	0.6	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.1	0.6	GO:0007405	neuroblast proliferation(GO:0007405)
0.1	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.1	0.1	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.1	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.1	GO:0051953	negative regulation of amine transport(GO:0051953)
0.1	0.3	GO:0045844	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.1	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.3	GO:0043588	skin development(GO:0043588)
0.1	0.1	GO:0031268	pseudopodium organization(GO:0031268)
0.1	0.1	GO:1902667	regulation of axon guidance(GO:1902667)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	1.5	GO:0007613	memory(GO:0007613)
0.1	0.1	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.1	0.2	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1	0.7	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.1	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.1	0.3	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.1	1.0	GO:0046068	cGMP metabolic process(GO:0046068)
0.1	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.2	GO:0001660	fever generation(GO:0001660)
0.1	0.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	0.2	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1	0.5	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	1.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.1	0.2	GO:0051788	response to misfolded protein(GO:0051788)
0.1	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.4	GO:0009404	toxin metabolic process(GO:0009404)
0.1	0.1	GO:0050955	thermoception(GO:0050955)
0.1	0.2	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.1	0.3	GO:0051145	smooth muscle cell differentiation(GO:0051145)
0.1	0.3	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.3	GO:0021511	spinal cord patterning(GO:0021511)
0.1	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.1	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.1	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.2	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.1	0.2	GO:0007567	parturition(GO:0007567)
0.1	0.3	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.0	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.3	GO:0045117	azole transport(GO:0045117)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.3	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.7	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.6	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0045188	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0046880	regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.3	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.2	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.2	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0060073	micturition(GO:0060073)
0.0	0.4	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0002885	positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866) positive regulation of hypersensitivity(GO:0002885)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0016441	posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194) gene silencing by miRNA(GO:0035195)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.2	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.4	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.6	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.3	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.6	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.3	GO:0001508	action potential(GO:0001508)
0.0	0.3	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.4	GO:2000181	negative regulation of blood vessel morphogenesis(GO:2000181)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.4	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.2	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.4	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.0	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0071605	response to L-ascorbic acid(GO:0033591) monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.6	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.7	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.0	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.0	GO:0060405	regulation of penile erection(GO:0060405)
0.0	0.2	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.8	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0048333	mesodermal cell differentiation(GO:0048333)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0021879	forebrain neuron differentiation(GO:0021879)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.4	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.0	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.3	GO:0021772	olfactory bulb development(GO:0021772)
0.0	0.2	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.3	GO:0042438	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.3	GO:0031103	axon regeneration(GO:0031103)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.1	GO:0060840	artery development(GO:0060840)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0	0.1	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.4	GO:0042402	amine catabolic process(GO:0009310) cellular biogenic amine catabolic process(GO:0042402)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.3	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.2	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.6	GO:0032006	regulation of TOR signaling(GO:0032006)
0.0	0.2	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0060192	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.1	GO:0061245	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0021508	floor plate formation(GO:0021508)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.3	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0043084	penile erection(GO:0043084)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.7	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.0	0.2	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.0	0.2	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.0	GO:0003156	regulation of organ formation(GO:0003156)
0.0	0.1	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.3	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	0.1	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0048663	neuron fate commitment(GO:0048663)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0042482	positive regulation of odontogenesis(GO:0042482)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.2	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0051147	regulation of muscle cell differentiation(GO:0051147)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.2	GO:0050999	regulation of nitric-oxide synthase activity(GO:0050999)
0.0	0.1	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.0	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
0.0	0.1	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0060420	regulation of heart growth(GO:0060420)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0035567	non-canonical Wnt signaling pathway(GO:0035567)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.2	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0014909	smooth muscle cell migration(GO:0014909)
0.0	0.0	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.2	GO:0099518	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.2	GO:0030901	midbrain development(GO:0030901)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.0	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.4	GO:0007030	Golgi organization(GO:0007030)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0032276	regulation of gonadotropin secretion(GO:0032276)
0.0	0.0	GO:0043049	otic placode formation(GO:0043049)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.0	GO:0021510	spinal cord development(GO:0021510)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.1	GO:0090280	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.2	GO:0045980	negative regulation of nucleotide metabolic process(GO:0045980)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.0	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.0	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.0	GO:0060231	mesenchymal to epithelial transition(GO:0060231) renal vesicle morphogenesis(GO:0072077)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0050773	regulation of dendrite development(GO:0050773)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.0	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0001975	response to amphetamine(GO:0001975)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	1.3	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.1	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.0	GO:0021571	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.2	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.6	GO:0007588	excretion(GO:0007588)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:0060602	branch elongation of an epithelium(GO:0060602)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0050807	regulation of synapse organization(GO:0050807)
0.0	0.0	GO:0048747	muscle fiber development(GO:0048747)
0.0	0.1	GO:0071600	otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0	0.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.0	0.0	GO:0045649	regulation of macrophage differentiation(GO:0045649)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.0	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.1	GO:0010824	regulation of centrosome duplication(GO:0010824)
0.0	0.1	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.0	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.0	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0014048	regulation of glutamate secretion(GO:0014048) positive regulation of amino acid transport(GO:0051957)
0.0	0.0	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.8	GO:0006936	muscle contraction(GO:0006936)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.1	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.0	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.0	0.0	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307) DNA dealkylation(GO:0035510)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0048167	regulation of synaptic plasticity(GO:0048167)
0.0	0.3	GO:0001764	neuron migration(GO:0001764)
0.0	0.0	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0048839	inner ear development(GO:0048839)
0.0	0.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0045616	regulation of keratinocyte differentiation(GO:0045616)
0.0	0.1	GO:0072348	sulfur compound transport(GO:0072348)
0.0	0.3	GO:0060070	canonical Wnt signaling pathway(GO:0060070)
0.0	0.0	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.0	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.2	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.3	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) actin-mediated cell contraction(GO:0070252)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0010460	positive regulation of heart rate(GO:0010460)
0.0	0.0	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0072501	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.0	GO:0060042	retina morphogenesis in camera-type eye(GO:0060042)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	1.0	GO:0008544	epidermis development(GO:0008544)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0032324	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	1.3	GO:0006813	potassium ion transport(GO:0006813)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.7	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.4	1.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	1.0	GO:0043260	laminin-11 complex(GO:0043260)
0.2	1.0	GO:0005606	laminin-1 complex(GO:0005606)
0.2	1.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.2	0.5	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.9	GO:0071437	invadopodium(GO:0071437)
0.2	1.0	GO:0005915	zonula adherens(GO:0005915)
0.2	1.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.2	0.6	GO:0016342	catenin complex(GO:0016342)
0.2	0.5	GO:0005588	collagen type V trimer(GO:0005588)
0.2	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	1.2	GO:0005614	interstitial matrix(GO:0005614)
0.1	1.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.6	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0070852	cell body fiber(GO:0070852)
0.1	1.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.5	GO:0030673	axolemma(GO:0030673)
0.1	0.4	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.3	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.8	GO:0005581	collagen trimer(GO:0005581)
0.1	5.2	GO:0005604	basement membrane(GO:0005604)
0.1	0.6	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1	0.3	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.9	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	0.8	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.5	GO:0031430	M band(GO:0031430)
0.1	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.4	GO:0001527	microfibril(GO:0001527)
0.1	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	0.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.8	GO:0043034	costamere(GO:0043034)
0.1	0.3	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	1.3	GO:0005811	lipid particle(GO:0005811)
0.1	0.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	5.5	GO:0060076	excitatory synapse(GO:0060076)
0.1	13.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.7	GO:0030315	T-tubule(GO:0030315)
0.1	0.4	GO:0010369	chromocenter(GO:0010369)
0.1	1.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.1	0.2	GO:0005638	lamin filament(GO:0005638)
0.1	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.1	3.2	GO:0030426	growth cone(GO:0030426)
0.1	0.4	GO:0032589	neuron projection membrane(GO:0032589)
0.1	2.8	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.1	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.7	GO:0044447	axoneme part(GO:0044447)
0.1	1.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.0	GO:0016460	myosin II complex(GO:0016460)
0.0	0.1	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.9	GO:0030057	desmosome(GO:0030057)
0.0	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.3	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	2.3	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.0	GO:0030018	Z disc(GO:0030018)
0.0	0.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	2.7	GO:0043292	contractile fiber(GO:0043292)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.8	GO:0030286	dynein complex(GO:0030286)
0.0	5.2	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.4	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.9	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.6	GO:0043679	axon terminus(GO:0043679)
0.0	0.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.5	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.3	GO:0031594	neuromuscular junction(GO:0031594)
0.0	1.3	GO:0097060	synaptic membrane(GO:0097060)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.4	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	1.4	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.2	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0032806	carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	1.3	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.5	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.7	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.6	GO:0045202	synapse(GO:0045202)
0.0	0.1	GO:0032982	myosin filament(GO:0032982)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	1.5	GO:0036477	somatodendritic compartment(GO:0036477)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.3	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	0.2	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:0048495	Roundabout binding(GO:0048495)
0.4	3.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3	0.3	GO:0043208	glycosphingolipid binding(GO:0043208)
0.3	0.9	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	0.9	GO:0002162	dystroglycan binding(GO:0002162)
0.3	0.9	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	0.8	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.3	2.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	0.8	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	0.8	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2	0.5	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	0.5	GO:0045545	syndecan binding(GO:0045545)
0.2	0.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	2.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.2	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.2	0.7	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2	0.7	GO:0034056	estrogen response element binding(GO:0034056)
0.2	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.2	1.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.2	0.7	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	0.5	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.2	3.5	GO:0005109	frizzled binding(GO:0005109)
0.2	0.7	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	1.0	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	0.6	GO:0004470	malic enzyme activity(GO:0004470)
0.2	0.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	1.3	GO:0001968	fibronectin binding(GO:0001968)
0.2	0.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.2	0.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.2	0.6	GO:0050815	phosphoserine binding(GO:0050815)
0.2	0.5	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	0.5	GO:0005113	patched binding(GO:0005113)
0.1	0.6	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.6	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.7	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.9	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	0.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.4	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.4	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.4	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.1	3.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.8	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.4	GO:0043559	insulin binding(GO:0043559)
0.1	0.9	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.5	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.7	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	2.2	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.3	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	1.2	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.1	0.6	GO:0034235	GPI anchor binding(GO:0034235)
0.1	0.4	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.6	GO:0005499	vitamin D binding(GO:0005499)
0.1	1.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.5	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.4	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	1.5	GO:0045296	cadherin binding(GO:0045296)
0.1	0.8	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.3	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.4	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.3	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.3	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.3	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.3	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1	0.3	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.8	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.3	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.7	GO:0005243	gap junction channel activity(GO:0005243)
0.1	1.1	GO:0005523	tropomyosin binding(GO:0005523)
0.1	5.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.8	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0051380	norepinephrine binding(GO:0051380)
0.1	0.7	GO:0004954	prostanoid receptor activity(GO:0004954)
0.1	0.2	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.3	GO:0031404	chloride ion binding(GO:0031404)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.6	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	1.3	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.5	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.3	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.4	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	0.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.1	GO:0034711	inhibin binding(GO:0034711)
0.1	0.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.3	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.6	GO:0051378	serotonin binding(GO:0051378)
0.1	0.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.3	GO:0017081	chloride channel regulator activity(GO:0017081)
0.1	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.5	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	0.7	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	1.9	GO:0019199	transmembrane receptor protein kinase activity(GO:0019199)
0.1	0.5	GO:0008066	glutamate receptor activity(GO:0008066)
0.1	0.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.2	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1	0.9	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.2	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.1	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	0.3	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	1.1	GO:0005518	collagen binding(GO:0005518)
0.1	0.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	2.4	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.6	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.4	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	1.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.4	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.2	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	1.2	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.5	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.6	GO:0022839	ion gated channel activity(GO:0022839)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.8	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.3	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0002060	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.5	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	1.8	GO:0008201	heparin binding(GO:0008201)
0.0	0.3	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	3.5	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	1.3	GO:0051015	actin filament binding(GO:0051015)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	7.5	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.4	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.5	GO:0032934	sterol binding(GO:0032934)
0.0	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.4	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0008443	phosphofructokinase activity(GO:0008443)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.0	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	2.0	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.4	GO:0070405	ammonium ion binding(GO:0070405)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0016594	glycine binding(GO:0016594)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.0	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	8.2	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	1.0	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.0	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.5	GO:0003774	motor activity(GO:0003774)
0.0	0.3	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.3	GO:0016247	channel regulator activity(GO:0016247)
0.0	0.1	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.2	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.2	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0	0.0	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.2	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	7.3	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	1.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	3.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	4.6	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.1	2.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	4.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	1.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	13.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	1.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	1.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	0.3	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.0	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	1.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.5	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.8	PID BMP PATHWAY	BMP receptor signaling
0.0	0.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	6.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	4.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.3	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	3.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	0.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.3	0.6	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.2	4.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	9.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	1.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	1.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	0.7	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	1.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.5	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	0.7	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.8	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.1	1.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	1.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.4	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	2.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	1.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.2	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.7	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol

Results for SMAD4

Z-value: 2.08

Motif logo

Transcription factors associated with SMAD4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the SMAD4 motif across conditions

Conditions sorted by the z-value of the SMAD4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: