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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for SOX17

Z-value: 1.62

Motif logo

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Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
SOX17
ENSG00000164736.5 SRY-box transcription factor 17

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr8_55379610_55379761SOX1791900.261576-0.618.4e-02Click!
chr8_55367217_55367368SOX1732030.319968-0.609.0e-02Click!
chr8_55379904_55380055SOX1794840.260800-0.215.8e-01Click!
chr8_55382631_55383060SOX17123500.254611-0.206.0e-01Click!
chr8_55379220_55379441SOX1788350.2625740.166.9e-01Click!

Activity of the SOX17 motif across conditions

Conditions sorted by the z-value of the SOX17 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_39380930_39381081 0.65 ENSG00000206947
 .
 12272
 0.23
chr1_246750885_246751091 0.63 RP11-439E19.1
18187
 0.16
chr7_120630679_120630951 0.57 CPED1
 cadherin-like and PC-esterase domain containing 1
 1139
 0.51
chr11_128099186_128099450 0.56 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 275971
 0.01
chr4_181928306_181928668 0.56 ENSG00000251742
 .
 827774
 0.0
chr8_101522130_101522303 0.51 KB-1615E4.3
17460
 0.16
chr4_135119262_135119413 0.51 PABPC4L
 poly(A) binding protein, cytoplasmic 4-like
 3566
 0.39
chr22_46454527_46455045 0.51 RP6-109B7.3
3991
 0.12
chr9_21023989_21024197 0.47 PTPLAD2
 protein tyrosine phosphatase-like A domain containing 2
 7515
 0.22
chr19_34359259_34359976 0.47 ENSG00000240626
 .
 58913
 0.13
chr15_40812177_40812372 0.44 ENSG00000223313
 .
 9495
 0.11
chr17_77817761_77818338 0.44 CBX4
 chromobox homolog 4
 4821
 0.18
chr6_27205685_27206711 0.42 PRSS16
 protease, serine, 16 (thymus)
 9282
 0.19
chr4_682374_683342 0.41 MFSD7
 major facilitator superfamily domain containing 7
 74
 0.94
chr3_147127121_147127296 0.41 ZIC1
 Zic family member 1
 37
 0.97
chr2_216299376_216299642 0.41 FN1
 fibronectin 1
 1281
 0.4
chr2_19849364_19849515 0.41 TTC32
 tetratricopeptide repeat domain 32
 251963
 0.02
chr7_41740779_41741576 0.41 INHBA
 inhibin, beta A
 970
 0.56
chr7_15723235_15723386 0.40 MEOX2
 mesenchyme homeobox 2
 3127
 0.32
chr16_4161991_4162273 0.40 ADCY9
 adenylate cyclase 9
 1895
 0.4
chr2_161491624_161491775 0.40 RBMS1
 RNA binding motif, single stranded interacting protein 1
 141394
 0.05
chr10_17273946_17274204 0.39 VIM
 vimentin
 1467
 0.3
chr2_38303069_38303895 0.39 CYP1B1-AS1
 CYP1B1 antisense RNA 1
 156
 0.5
chr13_24006860_24007105 0.39 SACS
 spastic ataxia of Charlevoix-Saguenay (sacsin)
 859
 0.74
chr10_29633011_29633162 0.38 LYZL1
 lysozyme-like 1
 55096
 0.14
chr3_24527242_24527393 0.38 ENSG00000228791
 .
 8261
 0.19
chr6_148829582_148830289 0.38 ENSG00000223322
 .
 15441
 0.29
chr5_140698139_140698494 0.38 TAF7
 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
 2014
 0.13
chr5_127981549_127981700 0.38 FBN2
 fibrillin 2
 13254
 0.23
chr6_17924518_17924669 0.37 KIF13A
 kinesin family member 13A
 63101
 0.13
chr1_65991038_65991651 0.37 RP4-630A11.3
39255
 0.14
chr1_98623502_98623653 0.37 ENSG00000225206
 .
 111850
 0.07
chr7_134469694_134469845 0.37 CALD1
 caldesmon 1
 5340
 0.32
chr9_18476160_18476529 0.37 ADAMTSL1
 ADAMTS-like 1
 2113
 0.45
chr15_37395216_37395447 0.36 MEIS2
 Meis homeobox 2
 1827
 0.38
chr10_3336462_3336663 0.36 PITRM1
 pitrilysin metallopeptidase 1
 121559
 0.06
chr7_43494536_43494714 0.36 HECW1
 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
 24627
 0.21
chr13_30740237_30740399 0.36 ENSG00000266816
 .
 40518
 0.2
chr5_158176993_158177383 0.36 CTD-2363C16.1
232826
 0.02
chr21_30504177_30504355 0.36 MAP3K7CL
 MAP3K7 C-terminal like
 688
 0.61
chr12_111843881_111845308 0.36 SH2B3
 SH2B adaptor protein 3
 842
 0.62
chr8_93115764_93116215 0.36 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 475
 0.9
chr19_56332953_56333104 0.35 NLRP11
 NLR family, pyrin domain containing 11
 3425
 0.16
chr16_73087072_73087516 0.35 ZFHX3
 zinc finger homeobox 3
 5020
 0.25
chr5_151065179_151065606 0.35 SPARC
 secreted protein, acidic, cysteine-rich (osteonectin)
 601
 0.67
chr9_129884150_129884930 0.35 ANGPTL2
 angiopoietin-like 2
 373
 0.9
chr2_190043861_190044108 0.35 COL5A2
 collagen, type V, alpha 2
 621
 0.79
chr1_200045338_200045520 0.35 ENSG00000252860
 .
 22240
 0.18
chr4_145570819_145570970 0.35 HHIP
 hedgehog interacting protein
 3570
 0.28
chr2_198539523_198539712 0.35 RFTN2
 raftlin family member 2
 1102
 0.51
chr3_156793670_156793821 0.35 ENSG00000222499
 .
 58614
 0.11
chrX_95691065_95691216 0.34 ENSG00000223260
 .
 25359
 0.28
chr2_145261082_145261233 0.34 ZEB2
 zinc finger E-box binding homeobox 2
 13958
 0.24
chr18_2856996_2857255 0.34 EMILIN2
 elastin microfibril interfacer 2
 10097
 0.16
chr21_33893367_33893849 0.34 ENSG00000252045
 .
 17001
 0.16
chr2_150982202_150982420 0.33 RND3
 Rho family GTPase 3
 359585
 0.01
chr2_69480819_69481174 0.33 ENSG00000199460
 .
 70987
 0.09
chr3_128207705_128209147 0.33 RP11-475N22.4
326
 0.79
chr10_32096471_32096622 0.33 ARHGAP12
 Rho GTPase activating protein 12
 46562
 0.16
chr10_29824157_29824642 0.33 ENSG00000207612
 .
 9627
 0.19
chr14_56068035_56068254 0.33 KTN1
 kinectin 1 (kinesin receptor)
 366
 0.89
chr3_157158697_157158863 0.33 PTX3
 pentraxin 3, long
 4202
 0.3
chr18_5556544_5556701 0.33 ENSG00000252576
 .
 1650
 0.33
chr4_86702209_86702472 0.33 ARHGAP24
 Rho GTPase activating protein 24
 2481
 0.39
chr19_46167946_46168097 0.32 GIPR
 gastric inhibitory polypeptide receptor
 3481
 0.1
chr8_85513931_85514082 0.32 ENSG00000206701
 .
 64094
 0.14
chr15_96881050_96881298 0.32 ENSG00000222651
 .
 4684
 0.17
chr1_200003972_200004421 0.32 NR5A2
 nuclear receptor subfamily 5, group A, member 2
 7185
 0.18
chr1_101313202_101313363 0.32 EXTL2
 exostosin-like glycosyltransferase 2
 46938
 0.12
chr4_119763070_119763221 0.32 SEC24D
 SEC24 family member D
 3320
 0.33
chr12_19018320_19018530 0.32 CAPZA3
 capping protein (actin filament) muscle Z-line, alpha 3
 127380
 0.05
chr2_32182398_32182549 0.32 MEMO1
 mediator of cell motility 1
 5894
 0.21
chr6_106700141_106700423 0.32 ENSG00000244710
 .
 31304
 0.17
chr8_117133093_117133257 0.32 ENSG00000221793
 .
 15823
 0.28
chr11_76621964_76622115 0.32 ENSG00000212030
 .
 32763
 0.15
chr10_25836306_25836457 0.31 ENSG00000222543
 .
 153608
 0.04
chr16_86603613_86603777 0.31 RP11-463O9.5
2328
 0.23
chr1_78960116_78960267 0.31 PTGFR
 prostaglandin F receptor (FP)
 3434
 0.34
chr1_31500771_31500983 0.31 PUM1
 pumilio RNA-binding family member 1
 32926
 0.16
chr4_18059479_18059630 0.31 LCORL
 ligand dependent nuclear receptor corepressor-like
 36055
 0.23
chr2_205205743_205205894 0.31 PARD3B
 par-3 family cell polarity regulator beta
 204698
 0.03
chr21_36780972_36781123 0.31 ENSG00000211590
 .
 311966
 0.01
chr7_120631344_120631706 0.31 CPED1
 cadherin-like and PC-esterase domain containing 1
 1849
 0.35
chr11_112505510_112505661 0.31 ENSG00000212397
 .
 32410
 0.23
chr13_24007256_24007423 0.30 SACS
 spastic ataxia of Charlevoix-Saguenay (sacsin)
 502
 0.88
chr15_32963693_32963946 0.30 RP11-1000B6.2
1447
 0.36
chr11_58350202_58350353 0.30 ZFP91
 ZFP91 zinc finger protein
 3693
 0.18
chr1_120189851_120190681 0.30 ZNF697
 zinc finger protein 697
 130
 0.97
chr3_65583100_65583492 0.30 MAGI1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 114
 0.98
chr7_83821514_83821694 0.30 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 2613
 0.45
chrX_39949292_39950247 0.30 BCOR
 BCL6 corepressor
 6887
 0.33
chr14_53511502_53511653 0.30 RP11-368P15.3
8104
 0.26
chr4_15922747_15922942 0.30 FGFBP1
 fibroblast growth factor binding protein 1
 17127
 0.2
chr17_9862955_9863106 0.30 GAS7
 growth arrest-specific 7
 251
 0.94
chr1_95561956_95562107 0.30 TMEM56
 transmembrane protein 56
 20863
 0.12
chr12_13351879_13352395 0.30 EMP1
 epithelial membrane protein 1
 2417
 0.37
chr3_25470358_25470509 0.29 RARB
 retinoic acid receptor, beta
 631
 0.81
chr6_138864777_138865078 0.29 NHSL1
 NHS-like 1
 1921
 0.45
chr17_8825496_8825647 0.29 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 9737
 0.23
chr6_155214673_155214881 0.29 ENSG00000238963
 .
 11514
 0.18
chr12_120246427_120246712 0.29 CIT
 citron (rho-interacting, serine/threonine kinase 21)
 5382
 0.27
chr8_102372972_102373210 0.29 ENSG00000239211
 .
 37070
 0.18
chr12_56100408_56100559 0.29 ITGA7
 integrin, alpha 7
 1002
 0.31
chr6_76460588_76461018 0.29 MYO6
 myosin VI
 1754
 0.36
chr3_21792365_21792565 0.29 ZNF385D
 zinc finger protein 385D
 462
 0.89
chr2_12461385_12461536 0.29 ENSG00000207183
 .
 90167
 0.09
chrX_100672866_100673966 0.29 ENSG00000221132
 .
 9067
 0.11
chr6_168048486_168048637 0.29 AL009178.1
 Uncharacterized protein; cDNA FLJ43200 fis, clone FEBRA2007793
 147649
 0.04
chr7_69470975_69471136 0.29 AUTS2
 autism susceptibility candidate 2
 406458
 0.01
chr3_157160417_157160653 0.29 PTX3
 pentraxin 3, long
 5957
 0.27
chr5_32505011_32505171 0.29 SUB1
 SUB1 homolog (S. cerevisiae)
 26648
 0.2
chr10_126724055_126724287 0.29 ENSG00000264572
 .
 2732
 0.29
chr5_70315966_70316295 0.29 NAIP
 NLR family, apoptosis inhibitory protein
 407
 0.88
chr8_128651347_128651766 0.29 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
 96124
 0.08
chr8_83170035_83170244 0.29 SNX16
 sorting nexin 16
 415038
 0.01
chr6_57369643_57369794 0.28 ENSG00000212017
 .
 114788
 0.07
chr17_46671414_46671766 0.28 HOXB5
 homeobox B5
 267
 0.75
chr12_13255888_13256039 0.28 GSG1
 germ cell associated 1
 613
 0.76
chr7_18810301_18810537 0.28 ENSG00000222164
 .
 37483
 0.22
chr10_95239818_95240064 0.28 MYOF
 myoferlin
 2010
 0.32
chr6_81232911_81233062 0.28 BCKDHB
 branched chain keto acid dehydrogenase E1, beta polypeptide
 416603
 0.01
chr18_9675042_9675193 0.28 RAB31
 RAB31, member RAS oncogene family
 33045
 0.15
chr3_170147186_170147337 0.28 CLDN11
 claudin 11
 10406
 0.26
chr12_84472792_84472943 0.28 ENSG00000221148
 .
 104360
 0.09
chr15_96888963_96889465 0.28 ENSG00000222651
 .
 12724
 0.15
chr3_149371362_149371801 0.28 WWTR1-AS1
 WWTR1 antisense RNA 1
 3226
 0.2
chr2_74413202_74413353 0.28 CATX-2
 HCG1989573; Uncharacterized protein
 5240
 0.14
chr2_54435704_54435855 0.28 ENSG00000252934
 .
 41635
 0.15
chrX_53078746_53079004 0.28 GPR173
 G protein-coupled receptor 173
 410
 0.85
chr3_32344642_32344793 0.28 ENSG00000207857
 .
 43497
 0.14
chr10_3666400_3666551 0.28 RP11-184A2.3
126784
 0.06
chr10_63818920_63819071 0.28 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 10025
 0.27
chr6_117920563_117920770 0.28 GOPC
 golgi-associated PDZ and coiled-coil motif containing
 2861
 0.34
chr6_3825964_3826270 0.28 RP11-420L9.4
6050
 0.22
chr21_33867197_33867430 0.28 ENSG00000252045
 .
 43296
 0.11
chr8_116675050_116675578 0.27 TRPS1
 trichorhinophalangeal syndrome I
 1409
 0.6
chr10_89822354_89822505 0.27 ENSG00000200891
 .
 67977
 0.12
chr7_92327286_92327437 0.27 ENSG00000206763
 .
 3767
 0.31
chr15_56035451_56035609 0.27 PRTG
 protogenin
 242
 0.94
chr4_48256193_48256344 0.27 TEC
 tec protein tyrosine kinase
 15613
 0.23
chr13_76213824_76214088 0.27 LMO7
 LIM domain 7
 3497
 0.21
chr7_55001398_55001578 0.27 ENSG00000252054
 .
 67977
 0.12
chr5_135365829_135365985 0.27 TGFBI
 transforming growth factor, beta-induced, 68kDa
 1216
 0.52
chr5_74862582_74862812 0.27 POLK
 polymerase (DNA directed) kappa
 19849
 0.15
chr12_960802_961189 0.27 WNK1
 WNK lysine deficient protein kinase 1
 136
 0.97
chr14_73881950_73882101 0.27 NUMB
 numb homolog (Drosophila)
 5246
 0.21
chr8_94238484_94238635 0.27 AC016885.1
 Uncharacterized protein
 3308
 0.29
chr12_78336292_78336638 0.27 NAV3
 neuron navigator 3
 23591
 0.28
chr12_29397730_29397881 0.27 FAR2
 fatty acyl CoA reductase 2
 21127
 0.23
chr6_11219192_11219343 0.27 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 13624
 0.22
chr11_63647826_63647977 0.27 ENSG00000202089
 .
 2256
 0.22
chr6_46900604_46900792 0.27 GPR116
 G protein-coupled receptor 116
 10984
 0.22
chr5_172195314_172195493 0.27 DUSP1
 dual specificity phosphatase 1
 2795
 0.19
chr17_46177753_46179071 0.27 CBX1
 chromobox homolog 1
 148
 0.91
chr11_10479478_10479629 0.27 AMPD3
 adenosine monophosphate deaminase 3
 1820
 0.36
chr5_158128189_158128340 0.26 CTD-2363C16.1
281750
 0.01
chr1_186944219_186944581 0.26 PLA2G4A
 phospholipase A2, group IVA (cytosolic, calcium-dependent)
 146278
 0.05
chr12_54017495_54017675 0.26 ATF7
 activating transcription factor 7
 2170
 0.23
chr9_74295565_74295716 0.26 TMEM2
 transmembrane protein 2
 24208
 0.27
chr6_18551314_18551465 0.26 ENSG00000207775
 .
 20626
 0.27
chr12_80987527_80987740 0.26 RP11-272K23.3
153
 0.97
chr4_186577993_186578477 0.26 SORBS2
 sorbin and SH3 domain containing 2
 112
 0.97
chr1_22345507_22345745 0.26 ENSG00000201273
 .
 8148
 0.1
chr6_76504796_76504947 0.26 MYO6
 myosin VI
 22369
 0.17
chr5_60962215_60962366 0.26 ENSG00000212215
 .
 2224
 0.32
chr3_1098193_1098344 0.26 ENSG00000244169
 .
 9291
 0.28
chrX_42106034_42106185 0.26 ENSG00000206896
 .
 72471
 0.12
chr11_133944204_133944355 0.26 JAM3
 junctional adhesion molecule 3
 5313
 0.26
chr5_121412020_121412268 0.26 LOX
 lysyl oxidase
 1836
 0.4
chr15_49715580_49715731 0.26 FGF7
 fibroblast growth factor 7
 198
 0.96
chr9_91606379_91607009 0.26 S1PR3
 sphingosine-1-phosphate receptor 3
 332
 0.78
chr8_50969798_50969978 0.26 SNTG1
 syntrophin, gamma 1
 145183
 0.05
chr13_94361906_94362057 0.26 GPC6-AS2
 GPC6 antisense RNA 2
 126416
 0.06
chr7_15723868_15724269 0.26 MEOX2
 mesenchyme homeobox 2
 2369
 0.37
chr20_46043998_46044155 0.26 ZMYND8
 zinc finger, MYND-type containing 8
 58509
 0.09
chr15_48959812_48960090 0.25 FBN1
 fibrillin 1
 21905
 0.23
chr11_12204433_12204584 0.25 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 20805
 0.23
chr5_69758456_69758685 0.25 RP11-497H16.7
10705
 0.27
chr3_147648289_147648638 0.25 ENSG00000221431
 .
 19175
 0.29
chr12_115813083_115813371 0.25 RP11-116D17.1
 HCG2038717; Uncharacterized protein
 12410
 0.32
chr21_28168221_28168372 0.25 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 47041
 0.18
chr5_52211157_52211369 0.25 ITGA2
 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
 73893
 0.1
chr1_101186076_101186227 0.25 VCAM1
 vascular cell adhesion molecule 1
 831
 0.73
chr8_97744511_97744662 0.25 CPQ
 carboxypeptidase Q
 28616
 0.25
chr8_17814649_17814800 0.25 PCM1
 pericentriolar material 1
 15368
 0.21
chr10_33230803_33231099 0.25 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 5772
 0.31
chr18_65691492_65691643 0.25 DSEL
 dermatan sulfate epimerase-like
 507350
 0.0
chr20_30457693_30458808 0.25 DUSP15
 dual specificity phosphatase 15
 125
 0.67
chr2_46295244_46295493 0.25 AC017006.2
10599
 0.26
chr4_81192543_81192855 0.25 FGF5
 fibroblast growth factor 5
 4906
 0.28
chr12_68055164_68055319 0.25 RP11-335O4.3
9458
 0.25
chr4_182878700_182878851 0.25 ENSG00000251742
 .
 122514
 0.06
chr6_11655417_11655591 0.25 ENSG00000207419
 .
 54548
 0.15
chr2_11508011_11508277 0.25 ROCK2
 Rho-associated, coiled-coil containing protein kinase 2
 23433
 0.2
chr9_20604527_20604679 0.25 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
 17269
 0.19
chr18_29239238_29239389 0.25 ENSG00000252379
 .
 10028
 0.16
chr6_17282088_17282659 0.25 RBM24
 RNA binding motif protein 24
 78
 0.99
chr12_106667138_106667289 0.24 ENSG00000238609
 .
 9554
 0.17
chr17_70339032_70339432 0.24 SOX9
 SRY (sex determining region Y)-box 9
 222071
 0.02
chr6_19804205_19805055 0.24 ID4
 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
 32987
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0052257 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.2 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0008228 opsonization(GO:0008228)
0.1 0.1 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1 0.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.3 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.3 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 0.2 GO:0014034 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.1 GO:0001743 optic placode formation(GO:0001743)
0.1 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.2 GO:0010800 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.5 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.5 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.0 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0060872 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152) kidney smooth muscle tissue development(GO:0072194)
0.0 0.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0090026 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0043113 receptor clustering(GO:0043113)
0.0 0.3 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.1 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0007442 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.3 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.1 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.6 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.2 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0030318 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0 0.0 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.0 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.0 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0001940 male pronucleus(GO:0001940)
0.1 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.9 GO:0044420 extracellular matrix component(GO:0044420)
0.0 0.1 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 2.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation