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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for SOX3_SOX2

Z-value: 3.87

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Transcription factors associated with SOX3_SOX2

Gene Symbol	Gene ID	Gene Info
SOX3 Ensembl NCBI GeneCards UniProt	ENSG00000134595.6	SRY-box transcription factor 3
SOX2 Ensembl NCBI GeneCards UniProt	ENSG00000181449.2	SRY-box transcription factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_181441891_181442042	SOX2	12244	0.226418	0.90	8.4e-04	Click!
chr3_181434209_181434555	SOX2	4660	0.262090	0.87	2.1e-03	Click!
chr3_181433689_181433840	SOX2	4042	0.272969	0.86	3.3e-03	Click!
chr3_181428768_181428923	SOX2	869	0.664602	0.84	4.5e-03	Click!
chr3_181437278_181437429	SOX2	7631	0.239195	0.83	5.6e-03	Click!
chrX_139585933_139586175	SOX3	1171	0.629728	0.74	2.4e-02	Click!
chrX_139608216_139608367	SOX3	21066	0.259141	0.69	4.0e-02	Click!
chrX_139585587_139585739	SOX3	1562	0.532114	0.54	1.3e-01	Click!
chrX_139584851_139585024	SOX3	2288	0.427320	0.53	1.4e-01	Click!
chrX_139589902_139590053	SOX3	2752	0.391077	0.49	1.9e-01	Click!

Activity of the SOX3_SOX2 motif across conditions

Conditions sorted by the z-value of the SOX3_SOX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_184797459_184798247	1.68	STOX2	storkhead box 2	28656	0.22
chr15_39876247_39876621	1.42	THBS1	thrombospondin 1	3140	0.25
chr9_18476160_18476529	1.37	ADAMTSL1	ADAMTS-like 1	2113	0.45
chr13_110958781_110959436	1.36	COL4A1	collagen, type IV, alpha 1	370	0.6
chr5_83680091_83680703	1.36	CTD-2269F5.1		23	0.71
chr1_17866390_17866720	1.27	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	225	0.95
chr6_150176715_150177267	1.26	RP11-350J20.12		3393	0.15
chr11_57546160_57546525	1.25	CTNND1	catenin (cadherin-associated protein), delta 1	2733	0.22
chr4_157890038_157890662	1.24	PDGFC	platelet derived growth factor C	1705	0.41
chr17_39861478_39861907	1.22	GAST	gastrin	6886	0.1
chr7_78398482_78399243	1.21	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	1534	0.56
chr4_86700210_86700446	1.19	ARHGAP24	Rho GTPase activating protein 24	469	0.88
chr13_24007498_24007984	1.17	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	100	0.98
chr7_143579344_143579634	1.16	FAM115A	family with sequence similarity 115, member A	487	0.8
chr15_30112674_30113382	1.11	TJP1	tight junction protein 1	723	0.64
chr1_98514169_98514606	1.07	ENSG00000225206	.	2660	0.42
chr11_121970307_121971111	1.07	ENSG00000207971	.	157	0.79
chr2_189839524_189839773	1.06	COL3A1	collagen, type III, alpha 1	549	0.79
chr10_24755480_24755818	1.04	KIAA1217	KIAA1217	189	0.96
chr7_82071524_82071810	1.03	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	1364	0.61
chr15_92104669_92104931	1.02	ENSG00000238981	.	273809	0.01
chr15_56208944_56209204	1.02	NEDD4	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	232	0.95
chr5_125337918_125338211	1.01	ENSG00000265637	.	194464	0.03
chr7_55001398_55001578	1.00	ENSG00000252054	.	67977	0.12
chr12_95009320_95010015	1.00	TMCC3	transmembrane and coiled-coil domain family 3	170	0.97
chr5_140802398_140802934	0.99	PCDHGA11	protocadherin gamma subfamily A, 11	1871	0.13
chr17_58821066_58821723	0.99	ENSG00000252534	.	5013	0.22
chr19_41195400_41196566	0.99	NUMBL	numb homolog (Drosophila)-like	44	0.96
chr4_23890359_23890765	0.98	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	1096	0.66
chrX_110038687_110039773	0.98	CHRDL1	chordin-like 1	56	0.99
chrX_69674453_69675874	0.97	DLG3	discs, large homolog 3 (Drosophila)	217	0.75
chr13_38171648_38172094	0.97	POSTN	periostin, osteoblast specific factor	992	0.71
chr7_134465998_134466492	0.97	CALD1	caldesmon 1	1816	0.49
chr22_46423027_46423794	0.97	RP6-109B7.5		25563	0.09
chr3_112358713_112358917	0.97	CCDC80	coiled-coil domain containing 80	1301	0.54
chr7_116312458_116312799	0.96	MET	met proto-oncogene	169	0.97
chr2_45823201_45823510	0.96	SRBD1	S1 RNA binding domain 1	15065	0.21
chrX_10586840_10587300	0.95	MID1	midline 1 (Opitz/BBB syndrome)	1389	0.54
chr16_89990293_89990742	0.95	TUBB3	Tubulin beta-3 chain	743	0.44
chr1_153584096_153584410	0.95	S100A16	S100 calcium binding protein A16	1306	0.22
chr15_48894702_48894960	0.94	FBN1	fibrillin 1	43087	0.18
chr8_2199973_2200269	0.94	MYOM2	myomesin 2	206937	0.03
chr1_150245669_150245859	0.93	C1orf54	chromosome 1 open reading frame 54	581	0.54
chr15_95388341_95388759	0.93	MCTP2	multiple C2 domains, transmembrane 2	489347	0.01
chr4_152146952_152147499	0.93	SH3D19	SH3 domain containing 19	7	0.98
chr12_100987398_100987560	0.92	GAS2L3	growth arrest-specific 2 like 3	83	0.98
chr1_234445927_234446133	0.92	ENSG00000264377	.	3817	0.19
chr9_13278507_13279169	0.91	RP11-272P10.2		348	0.67
chr4_187647302_187647732	0.91	FAT1	FAT atypical cadherin 1	359	0.93
chr13_38443188_38443573	0.90	TRPC4	transient receptor potential cation channel, subfamily C, member 4	480	0.86
chr9_12776574_12776837	0.89	LURAP1L	leucine rich adaptor protein 1-like	1685	0.38
chr1_11751224_11751616	0.89	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	114	0.78
chr13_24007256_24007423	0.89	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	502	0.88
chr1_956379_957022	0.88	AGRN	agrin	1197	0.27
chr17_78044749_78045392	0.88	CCDC40	coiled-coil domain containing 40	12346	0.15
chr2_15310036_15310187	0.88	NBAS	neuroblastoma amplified sequence	20410	0.29
chr10_10834416_10834694	0.88	CELF2	CUGBP, Elav-like family member 2	212704	0.02
chr15_42749089_42749416	0.87	ZNF106	zinc finger protein 106	459	0.78
chr10_79647530_79647963	0.87	AL391421.1	Uncharacterized protein; cDNA FLJ43696 fis, clone TBAES2007964	21113	0.15
chr19_34359259_34359976	0.86	ENSG00000240626	.	58913	0.13
chrX_132549723_132550137	0.86	GPC4	glypican 4	412	0.9
chr18_6729547_6730123	0.86	ARHGAP28	Rho GTPase activating protein 28	14	0.5
chr2_20348576_20349061	0.84	ENSG00000266059	.	26289	0.15
chr3_139258681_139258897	0.84	RP11-319G6.1		31	0.6
chr12_123754396_123755524	0.84	CDK2AP1	cyclin-dependent kinase 2 associated protein 1	728	0.52
chr3_98700853_98701271	0.84	ENSG00000207331	.	73759	0.1
chr7_117512754_117513170	0.84	CTTNBP2	cortactin binding protein 2	599	0.85
chr5_15752995_15753164	0.83	FBXL7	F-box and leucine-rich repeat protein 7	136988	0.05
chr4_150999769_151000790	0.83	DCLK2	doublecortin-like kinase 2	99	0.98
chr2_1711742_1712354	0.82	PXDN	peroxidasin homolog (Drosophila)	15706	0.26
chr8_67454441_67454873	0.82	ENSG00000206949	.	41111	0.13
chr17_31255277_31255844	0.82	TMEM98	transmembrane protein 98	332	0.89
chr6_44510355_44510599	0.81	ENSG00000266619	.	107099	0.06
chr9_130639317_130639975	0.81	AK1	adenylate kinase 1	376	0.71
chr1_201619186_201619405	0.81	NAV1	neuron navigator 1	1845	0.29
chr17_47077080_47077320	0.80	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	2092	0.16
chr22_47225649_47225912	0.80	ENSG00000221672	.	18023	0.21
chr11_46670801_46671004	0.80	ATG13	autophagy related 13	10070	0.15
chr8_93115764_93116215	0.80	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	475	0.9
chr3_40821863_40822477	0.80	ZNF621	zinc finger protein 621	255263	0.02
chr15_23743478_23743629	0.80	GOLGA6L2	golgin A6 family-like 2	51172	0.11
chr4_187765290_187765672	0.80	ENSG00000252382	.	13129	0.29
chr17_49123926_49124134	0.80	SPAG9	sperm associated antigen 9	209	0.93
chr9_18473799_18474008	0.79	ADAMTSL1	ADAMTS-like 1	11	0.99
chr15_99847895_99848073	0.78	AC022819.2	Uncharacterized protein	11844	0.18
chr2_107503478_107503965	0.78	ST6GAL2	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	157	0.97
chr11_123059250_123059539	0.78	CTD-2216M2.1		116	0.97
chr6_56557534_56557976	0.78	DST	dystonin	49961	0.18
chr6_27205685_27206711	0.77	PRSS16	protease, serine, 16 (thymus)	9282	0.19
chrX_151039282_151039625	0.77	RP11-366F6.2		40218	0.13
chr2_38303069_38303895	0.77	CYP1B1-AS1	CYP1B1 antisense RNA 1	156	0.5
chr12_64239539_64239880	0.77	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	1168	0.42
chr4_71589225_71589655	0.76	RUFY3	RUN and FYVE domain containing 3	1068	0.4
chr3_159484310_159484461	0.76	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough	1493	0.34
chr11_89027115_89027763	0.76	TYR	tyrosinase	116819	0.06
chr17_76210613_76211139	0.76	BIRC5	baculoviral IAP repeat containing 5	410	0.76
chr3_114403957_114404345	0.76	ENSG00000264623	.	58221	0.14
chr12_27398836_27399341	0.75	STK38L	serine/threonine kinase 38 like	498	0.86
chr6_19804205_19805055	0.75	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	32987	0.2
chr6_76645073_76645368	0.75	IMPG1	interphotoreceptor matrix proteoglycan 1	454	0.81
chr8_29664962_29665155	0.75	ENSG00000221003	.	121063	0.06
chr10_95196659_95197038	0.75	MYOF	myoferlin	45103	0.14
chr5_121647834_121648295	0.75	SNCAIP	synuclein, alpha interacting protein	132	0.9
chr2_235890317_235890698	0.75	SH3BP4	SH3-domain binding protein 4	239	0.97
chr1_156051080_156051411	0.74	MEX3A	mex-3 RNA binding family member A	544	0.52
chr7_27157625_27157776	0.74	HOXA3	homeobox A3	1514	0.16
chr12_71003154_71004126	0.74	PTPRB	protein tyrosine phosphatase, receptor type, B	16	0.99
chr1_243414977_243415342	0.74	CEP170	centrosomal protein 170kDa	1463	0.39
chr12_116962704_116963010	0.74	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2	34329	0.21
chr7_19812764_19813031	0.73	TMEM196	transmembrane protein 196	80	0.98
chr6_151562009_151562901	0.73	AKAP12	A kinase (PRKA) anchor protein 12	946	0.51
chr19_49864989_49865626	0.73	DKKL1	dickkopf-like 1	267	0.51
chr12_7037386_7038830	0.73	ATN1	atrophin 1	632	0.41
chr7_44920039_44920574	0.73	ENSG00000264326	.	1093	0.37
chr7_137028027_137028276	0.73	PTN	pleiotrophin	369	0.92
chr22_36235496_36235773	0.73	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	631	0.82
chr9_14353312_14353885	0.73	RP11-120J1.1		6279	0.28
chr11_89867867_89868379	0.73	NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2	109	0.97
chr4_420426_420577	0.73	ENSG00000211482	.	16903	0.16
chr1_162602563_162603214	0.73	DDR2	discoidin domain receptor tyrosine kinase 2	628	0.74
chr21_46825742_46826418	0.73	COL18A1	collagen, type XVIII, alpha 1	1028	0.47
chr7_96653221_96653741	0.73	DLX5	distal-less homeobox 5	781	0.6
chr14_33969119_33969270	0.72	NPAS3	neuronal PAS domain protein 3	235253	0.02
chr19_49228406_49228652	0.72	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator	5551	0.09
chr22_17679684_17679946	0.72	CECR1	cat eye syndrome chromosome region, candidate 1	858	0.6
chr1_7439604_7439992	0.72	RP3-453P22.2		9681	0.21
chr8_119964322_119964783	0.72	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	113	0.98
chr6_161649839_161650239	0.72	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	45012	0.2
chr12_29894510_29894661	0.71	TMTC1	transmembrane and tetratricopeptide repeat containing 1	42146	0.21
chr17_62737056_62737243	0.71	RP13-104F24.1		17572	0.18
chr6_19838575_19839711	0.71	RP1-167F1.2		168	0.95
chr19_1566819_1567637	0.71	MEX3D	mex-3 RNA binding family member D	301	0.76
chr3_16219029_16219297	0.71	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	2947	0.33
chr15_80696207_80696642	0.71	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2	269	0.71
chr11_76494408_76494819	0.71	TSKU	tsukushi, small leucine rich proteoglycan	330	0.61
chr6_163838395_163838889	0.71	QKI	QKI, KH domain containing, RNA binding	1295	0.63
chr18_31158744_31159369	0.71	ASXL3	additional sex combs like 3 (Drosophila)	426	0.91
chr7_22233198_22233366	0.70	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5	245	0.96
chr10_112038932_112039260	0.70	SMNDC1	survival motor neuron domain containing 1	25359	0.19
chr5_148787044_148787195	0.70	ENSG00000208035	.	21362	0.11
chr12_90341311_90341685	0.70	ENSG00000252823	.	193662	0.03
chr2_238318512_238318719	0.70	COL6A3	collagen, type VI, alpha 3	4176	0.24
chr18_40710046_40710304	0.70	RIT2	Ras-like without CAAX 2	14518	0.31
chr21_17942611_17942934	0.70	ENSG00000207863	.	19785	0.19
chr3_127454933_127455119	0.70	MGLL	monoglyceride lipase	174	0.96
chr14_23447268_23447766	0.69	AJUBA	ajuba LIM protein	571	0.5
chrX_66767815_66768085	0.69	AR	androgen receptor	2964	0.43
chr1_107467028_107467195	0.69	PRMT6	protein arginine methyltransferase 6	132156	0.06
chr2_6221567_6221718	0.69	DKFZP761K2322	HCG1990367; Putative uncharacterized protein DKFZp761K2322; Putative uncharacterized protein FLJ30594; Uncharacterized protein; cDNA FLJ30594 fis, clone BRAWH2008903	109930	0.08
chr4_81195528_81195918	0.69	FGF5	fibroblast growth factor 5	7930	0.26
chr15_68155525_68155920	0.68	ENSG00000206625	.	23339	0.22
chr12_133137038_133137885	0.68	P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	57905	0.1
chr18_13500432_13500753	0.68	RP11-53B2.5		696	0.52
chr8_142289533_142290316	0.68	RP11-10J21.3	Uncharacterized protein	25260	0.12
chr2_216299376_216299642	0.68	FN1	fibronectin 1	1281	0.4
chr4_171010363_171010619	0.68	AADAT	aminoadipate aminotransferase	54	0.98
chr7_105705910_105706365	0.68	SYPL1	synaptophysin-like 1	32171	0.2
chr4_114374175_114374326	0.68	ENSG00000206820	.	32771	0.17
chr8_97145200_97145762	0.68	GDF6	growth differentiation factor 6	27539	0.21
chr4_57973382_57973633	0.67	ENSG00000238541	.	996	0.47
chr3_44063258_44064101	0.67	ENSG00000252980	.	48900	0.17
chr17_27043546_27044298	0.67	RAB34	RAB34, member RAS oncogene family	844	0.24
chr15_60687597_60687748	0.67	ANXA2	annexin A2	1865	0.45
chr10_30138566_30138997	0.67	SVIL	supervillin	114048	0.06
chr1_95391078_95391415	0.66	CNN3	calponin 3, acidic	91	0.96
chr9_14096297_14096607	0.66	NFIB	nuclear factor I/B	84339	0.11
chr6_72188759_72189140	0.66	ENSG00000212099	.	59730	0.12
chr2_144303459_144303649	0.66	RP11-570L15.2		26120	0.19
chr15_93168724_93168875	0.66	FAM174B	family with sequence similarity 174, member B	13675	0.22
chr3_134092531_134092774	0.66	AMOTL2	angiomotin like 2	13	0.98
chr4_125632495_125632876	0.66	ANKRD50	ankyrin repeat domain 50	1202	0.67
chr8_42063953_42065062	0.66	PLAT	plasminogen activator, tissue	576	0.71
chr5_71506961_71507136	0.66	MAP1B	microtubule-associated protein 1B	31593	0.18
chr6_47276454_47277750	0.65	TNFRSF21	tumor necrosis factor receptor superfamily, member 21	539	0.86
chr5_15500636_15500842	0.65	FBXL7	F-box and leucine-rich repeat protein 7	434	0.91
chr5_88080560_88081020	0.65	MEF2C	myocyte enhancer factor 2C	38815	0.18
chr19_45347719_45348142	0.65	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	1502	0.27
chr4_77506894_77507309	0.65	ENSG00000265314	.	10397	0.17
chr3_114169976_114170457	0.65	ZBTB20	zinc finger and BTB domain containing 20	3314	0.33
chr7_34019967_34020212	0.65	BMPER	BMP binding endothelial regulator	74944	0.12
chr1_210057563_210057765	0.65	DIEXF	digestive organ expansion factor homolog (zebrafish)	45514	0.13
chr16_70669285_70669554	0.65	IL34	interleukin 34	11049	0.15
chr7_130595711_130595921	0.65	ENSG00000226380	.	33518	0.2
chr3_49169788_49170138	0.65	LAMB2	laminin, beta 2 (laminin S)	490	0.65
chr4_159969552_159969736	0.65	C4orf45	chromosome 4 open reading frame 45	13311	0.17
chr22_30640971_30641213	0.64	RP1-102K2.8		892	0.38
chr2_60743182_60743762	0.64	AC009970.1		20651	0.21
chr17_38601617_38601849	0.64	IGFBP4	insulin-like growth factor binding protein 4	2020	0.24
chr3_15899309_15899460	0.64	ANKRD28	ankyrin repeat domain 28	1894	0.38
chr7_140048721_140049206	0.64	SLC37A3	solute carrier family 37, member 3	477	0.77
chr9_124461801_124462223	0.64	DAB2IP	DAB2 interacting protein	363	0.92
chr1_244609044_244609215	0.64	ADSS	adenylosuccinate synthase	6307	0.21
chr15_39873424_39874712	0.64	THBS1	thrombospondin 1	774	0.66
chr15_99439700_99440117	0.64	RP11-654A16.1		3144	0.27
chr7_41740779_41741576	0.64	INHBA	inhibin, beta A	970	0.56
chr10_60515616_60516529	0.64	BICC1	bicaudal C homolog 1 (Drosophila)	37223	0.22
chr5_32791216_32791367	0.64	AC026703.1		2346	0.34
chr15_42082923_42083265	0.64	AC073657.1	Uncharacterized protein	6865	0.12
chr1_86046643_86047495	0.64	CYR61	cysteine-rich, angiogenic inducer, 61	625	0.71
chr12_24103066_24103383	0.63	SOX5	SRY (sex determining region Y)-box 5	587	0.86

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX3_SOX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.7	2.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.7	2.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.6	2.5	GO:0043589	skin morphogenesis(GO:0043589)
0.5	1.5	GO:0022605	oogenesis stage(GO:0022605)
0.5	1.9	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.4	1.8	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	1.3	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.4	1.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.4	1.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.4	1.2	GO:0031223	auditory behavior(GO:0031223)
0.4	0.8	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.4	1.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.4	1.1	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.4	1.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.4	0.4	GO:0032224	regulation of synaptic transmission, cholinergic(GO:0032222) positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.3	0.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.3	0.7	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.3	1.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.3	1.3	GO:0048539	bone marrow development(GO:0048539)
0.3	0.9	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.3	0.9	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.3	0.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.3	0.6	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.3	1.7	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.3	0.8	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.3	1.4	GO:0021670	lateral ventricle development(GO:0021670)
0.3	1.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.3	0.8	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3	0.8	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.3	1.6	GO:0016264	gap junction assembly(GO:0016264)
0.3	0.5	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2	1.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2	0.7	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.2	0.2	GO:0070141	response to UV-A(GO:0070141)
0.2	1.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	1.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.4	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.2	0.4	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.2	0.8	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.2	0.8	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.2	0.8	GO:0019695	choline metabolic process(GO:0019695)
0.2	0.6	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.2	0.4	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.2	1.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.2	0.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.2	1.0	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.2	0.6	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	0.6	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.2	0.4	GO:0001778	plasma membrane repair(GO:0001778)
0.2	0.8	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.2	1.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.2	1.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2	0.9	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	0.6	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2	0.4	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.2	0.7	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.2	1.3	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	0.9	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.2	0.4	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.2	0.7	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	0.4	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2	0.4	GO:1903332	regulation of protein folding(GO:1903332)
0.2	0.4	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2	0.5	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.2	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	1.7	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.2	2.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.2	0.5	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.2	0.7	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	0.5	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.2	0.3	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.2	1.2	GO:0009404	toxin metabolic process(GO:0009404)
0.2	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.7	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.2	1.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.2	0.2	GO:0003161	cardiac conduction system development(GO:0003161)
0.2	0.5	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.2	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.2	0.5	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.2	0.2	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.2	0.3	GO:0001880	Mullerian duct regression(GO:0001880)
0.2	0.2	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.2	0.6	GO:0008218	bioluminescence(GO:0008218)
0.2	0.2	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.2	0.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.2	2.9	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.2	0.5	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.1	1.2	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.4	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.4	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.4	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.3	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.1	0.6	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	0.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.7	GO:0030238	male sex determination(GO:0030238)
0.1	0.3	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	1.8	GO:0046697	decidualization(GO:0046697)
0.1	0.4	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.7	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.4	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.3	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	0.4	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.5	GO:0010800	regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1	2.6	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.1	3.0	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1	0.4	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.1	GO:0060592	mammary gland formation(GO:0060592) mammary placode formation(GO:0060596)
0.1	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.9	GO:0002076	osteoblast development(GO:0002076)
0.1	0.9	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	1.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	1.5	GO:0035329	hippo signaling(GO:0035329)
0.1	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.1	0.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.1	0.2	GO:0051597	response to methylmercury(GO:0051597)
0.1	0.4	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	1.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.1	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.6	GO:0060039	pericardium development(GO:0060039)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.6	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.3	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.1	0.4	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.1	0.3	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.1	2.1	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.2	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.2	GO:0045112	integrin biosynthetic process(GO:0045112)
0.1	0.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.4	GO:0021794	thalamus development(GO:0021794)
0.1	0.2	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.4	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	1.0	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	1.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.4	GO:1903318	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.1	0.3	GO:0016198	axon choice point recognition(GO:0016198)
0.1	0.4	GO:0000090	mitotic anaphase(GO:0000090)
0.1	0.5	GO:0019228	neuronal action potential(GO:0019228)
0.1	0.3	GO:0051451	myoblast migration(GO:0051451)
0.1	0.8	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.1	0.2	GO:0090009	primitive streak formation(GO:0090009)
0.1	1.0	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.5	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	0.7	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.7	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.3	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.9	GO:0008038	neuron recognition(GO:0008038)
0.1	0.3	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.2	GO:0016048	detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.1	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
0.1	0.4	GO:0021571	rhombomere 5 development(GO:0021571)
0.1	0.3	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.2	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.2	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.3	GO:0060840	artery development(GO:0060840)
0.1	0.4	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	0.1	GO:0061217	regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.1	0.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.3	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.8	GO:0000052	citrulline metabolic process(GO:0000052)
0.1	0.3	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.4	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	1.4	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:0061035	regulation of cartilage development(GO:0061035)
0.1	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.1	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	0.4	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.4	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.4	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.1	0.3	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.4	GO:0002068	glandular epithelial cell development(GO:0002068)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.6	GO:0021772	olfactory bulb development(GO:0021772)
0.1	0.4	GO:1901863	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.1	0.3	GO:0010107	potassium ion import(GO:0010107)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	1.7	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1	0.2	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.6	GO:0043113	receptor clustering(GO:0043113)
0.1	0.2	GO:0051797	regulation of hair follicle development(GO:0051797)
0.1	0.3	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.1	0.5	GO:0008228	opsonization(GO:0008228)
0.1	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	0.3	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.6	GO:0033189	response to vitamin A(GO:0033189)
0.1	0.5	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.1	0.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.1	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.1	0.3	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.1	0.4	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.2	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.1	0.6	GO:0033198	response to ATP(GO:0033198)
0.1	0.2	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.2	GO:0060013	righting reflex(GO:0060013)
0.1	0.2	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1	0.4	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
0.1	0.1	GO:0060976	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510) coronary vasculature development(GO:0060976)
0.1	0.2	GO:0003151	outflow tract morphogenesis(GO:0003151)
0.1	0.3	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.4	GO:0015871	choline transport(GO:0015871)
0.1	0.2	GO:0060009	Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.1	0.1	GO:0006547	histidine metabolic process(GO:0006547)
0.1	0.8	GO:0048566	embryonic digestive tract development(GO:0048566)
0.1	9.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	0.3	GO:0001660	fever generation(GO:0001660)
0.1	0.4	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.9	GO:0042554	superoxide anion generation(GO:0042554)
0.1	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.5	GO:0010171	body morphogenesis(GO:0010171)
0.1	0.3	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.3	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.1	GO:0055057	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.1	0.3	GO:0060736	prostate gland growth(GO:0060736)
0.1	0.2	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.1	0.1	GO:1903170	negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.3	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.1	0.2	GO:0090399	replicative senescence(GO:0090399)
0.1	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.1	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.2	GO:0048240	sperm capacitation(GO:0048240)
0.1	0.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.2	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.9	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.1	0.2	GO:0010893	positive regulation of steroid biosynthetic process(GO:0010893) positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.5	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.2	GO:0006563	L-serine metabolic process(GO:0006563) L-serine biosynthetic process(GO:0006564)
0.1	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.1	0.4	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.1	0.2	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1	0.3	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.1	0.1	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.3	GO:0009629	response to gravity(GO:0009629)
0.1	0.3	GO:0031000	response to caffeine(GO:0031000)
0.1	0.2	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	0.1	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	0.4	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.1	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.2	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.1	0.1	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.1	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.3	GO:0003341	cilium movement(GO:0003341)
0.1	2.2	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1	0.8	GO:0097479	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.1	0.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.1	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.1	0.1	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.1	0.2	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1	0.4	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.1	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.2	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.2	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.2	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.1	0.3	GO:0031103	axon regeneration(GO:0031103)
0.1	0.5	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.1	0.1	GO:0048333	mesodermal cell differentiation(GO:0048333)
0.1	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.3	GO:0045843	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.1	0.1	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.1	0.1	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0014904	myotube cell development(GO:0014904)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.0	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.1	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.3	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223) deoxyribose phosphate catabolic process(GO:0046386)
0.0	0.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.6	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0051153	regulation of striated muscle cell differentiation(GO:0051153)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.4	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.4	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	1.0	GO:0001843	neural tube closure(GO:0001843)
0.0	0.3	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.2	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.4	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.5	GO:0019827	stem cell population maintenance(GO:0019827)
0.0	0.5	GO:0001709	cell fate determination(GO:0001709)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	1.0	GO:0019233	sensory perception of pain(GO:0019233)
0.0	0.4	GO:0060674	placenta blood vessel development(GO:0060674)
0.0	0.0	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.2	GO:0046040	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	1.5	GO:0045444	fat cell differentiation(GO:0045444)
0.0	0.1	GO:0018126	protein hydroxylation(GO:0018126)
0.0	0.8	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.6	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.0	0.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.2	GO:0030901	midbrain development(GO:0030901)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0009651	response to salt stress(GO:0009651)
0.0	0.0	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.0	0.0	GO:0060602	branch elongation of an epithelium(GO:0060602)
0.0	0.2	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.0	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.2	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.0	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.2	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.2	GO:0034394	protein localization to cell surface(GO:0034394)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0043114	regulation of vascular permeability(GO:0043114)
0.0	0.2	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.1	GO:0071675	mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0	0.0	GO:0002027	regulation of heart rate(GO:0002027)
0.0	0.8	GO:0001649	osteoblast differentiation(GO:0001649)
0.0	0.1	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.8	GO:0072073	kidney epithelium development(GO:0072073)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.6	GO:0046068	cGMP metabolic process(GO:0046068)
0.0	0.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.5	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0	0.2	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:1902224	ketone body metabolic process(GO:1902224)
0.0	0.1	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0042160	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.2	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.2	GO:0098856	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.2	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.2	GO:0035094	response to nicotine(GO:0035094)
0.0	0.6	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0090398	cellular senescence(GO:0090398)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.4	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.2	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	2.8	GO:0006936	muscle contraction(GO:0006936)
0.0	0.0	GO:1901984	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0048747	muscle fiber development(GO:0048747)
0.0	0.4	GO:0009988	cell-cell recognition(GO:0009988)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.2	GO:0014075	response to amine(GO:0014075)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.3	GO:0021987	cerebral cortex development(GO:0021987)
0.0	0.2	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.1	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0060850	regulation of transcription involved in cell fate commitment(GO:0060850)
0.0	0.3	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.0	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.0	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932) regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.0	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.3	GO:0048167	regulation of synaptic plasticity(GO:0048167)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0001841	neural tube formation(GO:0001841)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.0	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.5	GO:0010977	negative regulation of neuron projection development(GO:0010977)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.5	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285) depurination(GO:0045007)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0045778	positive regulation of ossification(GO:0045778)
0.0	0.0	GO:1901160	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:2000108	positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of leukocyte apoptotic process(GO:2000108)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.3	GO:0061045	negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0007613	memory(GO:0007613)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.0	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.0	GO:0060487	lung epithelial cell differentiation(GO:0060487)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.5	GO:0007588	excretion(GO:0007588)
0.0	0.0	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.0	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.7	GO:0031424	keratinization(GO:0031424)
0.0	0.0	GO:2000193	positive regulation of fatty acid transport(GO:2000193)
0.0	0.0	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.0	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.0	0.0	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0060349	bone morphogenesis(GO:0060349)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.1	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.0	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0006558	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0036315	cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.2	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.0	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0090257	regulation of muscle system process(GO:0090257)
0.0	0.1	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:0015791	polyol transport(GO:0015791)
0.0	0.0	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.0	GO:0055002	striated muscle cell development(GO:0055002)
0.0	0.0	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0060749	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0	0.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.2	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0010596	negative regulation of endothelial cell migration(GO:0010596)
0.0	0.0	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.0	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0070852	cell body fiber(GO:0070852)
0.4	3.1	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.4	0.4	GO:0043260	laminin-11 complex(GO:0043260)
0.4	4.0	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4	1.8	GO:0071437	invadopodium(GO:0071437)
0.3	0.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	2.3	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.5	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	1.0	GO:0032059	bleb(GO:0032059)
0.2	1.7	GO:0005916	fascia adherens(GO:0005916)
0.2	1.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	1.5	GO:0005606	laminin-1 complex(GO:0005606)
0.2	0.6	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	1.3	GO:0005577	fibrinogen complex(GO:0005577)
0.2	0.8	GO:0005915	zonula adherens(GO:0005915)
0.2	0.5	GO:0032133	chromosome passenger complex(GO:0032133)
0.2	1.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	0.5	GO:0048179	activin receptor complex(GO:0048179)
0.2	0.9	GO:0001527	microfibril(GO:0001527)
0.2	2.9	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.5	GO:0043205	fibril(GO:0043205)
0.1	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.1	2.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	1.0	GO:0043034	costamere(GO:0043034)
0.1	1.3	GO:0005581	collagen trimer(GO:0005581)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.5	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.4	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.3	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	1.4	GO:0044447	axoneme part(GO:0044447)
0.1	0.3	GO:0043198	dendritic shaft(GO:0043198)
0.1	0.5	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.3	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	20.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.4	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1	0.7	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	2.5	GO:0030018	Z disc(GO:0030018)
0.1	0.4	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	4.5	GO:0030426	growth cone(GO:0030426)
0.1	0.4	GO:0001739	sex chromatin(GO:0001739)
0.1	0.4	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1	1.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	4.6	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1	0.3	GO:0030673	axolemma(GO:0030673)
0.1	0.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.5	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	1.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.3	GO:0016589	NURF complex(GO:0016589)
0.1	0.2	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.3	GO:0000801	central element(GO:0000801)
0.1	1.0	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.3	GO:0010369	chromocenter(GO:0010369)
0.0	0.0	GO:0031904	endosome lumen(GO:0031904)
0.0	2.4	GO:0031012	extracellular matrix(GO:0031012)
0.0	3.1	GO:0030016	myofibril(GO:0030016)
0.0	1.0	GO:0005922	connexon complex(GO:0005922)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0070382	exocytic vesicle(GO:0070382)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	7.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	1.4	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.3	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.3	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.7	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.4	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.3	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	3.1	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	1.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0031526	brush border membrane(GO:0031526)
0.0	0.3	GO:0005902	microvillus(GO:0005902)
0.0	0.4	GO:0030286	dynein complex(GO:0030286)
0.0	4.1	GO:0045202	synapse(GO:0045202)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	1.1	GO:0034705	potassium channel complex(GO:0034705)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.4	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	1.3	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.6	6.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.5	1.5	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.5	1.4	GO:0070052	collagen V binding(GO:0070052)
0.4	1.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.4	1.1	GO:0002162	dystroglycan binding(GO:0002162)
0.4	1.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	1.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.3	1.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.3	0.9	GO:0001601	peptide YY receptor activity(GO:0001601)
0.3	1.7	GO:0008432	JUN kinase binding(GO:0008432)
0.3	0.9	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.3	1.1	GO:0045499	chemorepellent activity(GO:0045499)
0.3	2.5	GO:0030544	Hsp70 protein binding(GO:0030544)
0.3	1.1	GO:0030172	troponin C binding(GO:0030172)
0.3	0.8	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	1.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.3	1.1	GO:0004470	malic enzyme activity(GO:0004470)
0.3	1.8	GO:0017080	sodium channel regulator activity(GO:0017080)
0.3	2.8	GO:0001968	fibronectin binding(GO:0001968)
0.3	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.7	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	1.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.2	0.7	GO:0045545	syndecan binding(GO:0045545)
0.2	0.7	GO:0033265	choline binding(GO:0033265)
0.2	0.6	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.2	0.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.8	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2	1.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.2	0.8	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2	1.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	1.0	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.2	0.9	GO:0061133	endopeptidase activator activity(GO:0061133)
0.2	2.1	GO:0005523	tropomyosin binding(GO:0005523)
0.2	1.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2	0.7	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2	0.5	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.2	1.8	GO:0045295	gamma-catenin binding(GO:0045295)
0.2	0.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.5	GO:0035198	miRNA binding(GO:0035198)
0.2	0.7	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.2	0.5	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2	1.9	GO:0004385	guanylate kinase activity(GO:0004385)
0.2	0.7	GO:0050897	cobalt ion binding(GO:0050897)
0.2	1.5	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.2	0.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.2	1.9	GO:0043394	proteoglycan binding(GO:0043394)
0.2	0.5	GO:0046923	ER retention sequence binding(GO:0046923)
0.2	0.6	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2	0.5	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.2	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.2	0.3	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.2	0.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2	0.9	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.4	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.7	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.7	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.7	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	2.8	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.4	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	1.2	GO:0051378	serotonin binding(GO:0051378)
0.1	0.5	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.8	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1	0.7	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.4	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.3	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	1.6	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.6	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.6	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.3	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	1.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	1.1	GO:0070064	proline-rich region binding(GO:0070064)
0.1	1.6	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.4	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.9	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.7	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	2.6	GO:0005518	collagen binding(GO:0005518)
0.1	0.8	GO:0050811	GABA receptor binding(GO:0050811)
0.1	1.3	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	0.3	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.9	GO:0005123	death receptor binding(GO:0005123)
0.1	0.5	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	0.3	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.7	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.4	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.3	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	1.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.5	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	5.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.0	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.4	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	1.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	0.2	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.7	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	1.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.5	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.4	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1	0.7	GO:0070717	poly-purine tract binding(GO:0070717)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.3	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	0.1	GO:0009374	biotin binding(GO:0009374)
0.1	0.3	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.3	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.6	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	1.9	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.6	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.7	GO:0019841	retinol binding(GO:0019841)
0.1	0.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	2.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.7	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1	0.2	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.2	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.5	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	0.2	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	0.5	GO:0019199	transmembrane receptor protein kinase activity(GO:0019199)
0.1	0.2	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.1	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.4	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.3	GO:0072349	modified amino acid transmembrane transporter activity(GO:0072349)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	0.8	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.1	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.5	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	1.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	2.1	GO:0051015	actin filament binding(GO:0051015)
0.0	0.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.4	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.4	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.4	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.6	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.2	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.4	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	3.8	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.7	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	2.4	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.8	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.4	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	1.6	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	5.7	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.3	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.0	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.0	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)
0.0	1.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.9	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.0	GO:0008252	nucleotidase activity(GO:0008252)
0.0	0.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	1.2	GO:0003774	motor activity(GO:0003774)
0.0	0.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	0.3	PID INSULIN PATHWAY	Insulin Pathway
0.2	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.2	9.8	NABA COLLAGENS	Genes encoding collagen proteins
0.2	0.7	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.2	1.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	3.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	5.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	1.1	PID ALK2 PATHWAY	ALK2 signaling events
0.1	3.3	PID BMP PATHWAY	BMP receptor signaling
0.1	1.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	1.9	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	2.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	1.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	2.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	1.0	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	1.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	1.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	0.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	1.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	2.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	0.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	1.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	0.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	9.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	0.7	PID ALK1 PATHWAY	ALK1 signaling events
0.1	1.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	1.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	1.3	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	7.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.8	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.6	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.0	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	0.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3	3.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	4.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	5.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	11.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	4.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2	3.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	1.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	1.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.5	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	0.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	0.2	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	0.2	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.1	1.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.5	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	0.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	0.7	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	0.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	2.1	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.6	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.0	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0	0.1	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport

Results for SOX3_SOX2

Z-value: 3.87

Motif logo

Transcription factors associated with SOX3_SOX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the SOX3_SOX2 motif across conditions

Conditions sorted by the z-value of the SOX3_SOX2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX3_SOX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: