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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for SOX4

Z-value: 1.30

Motif logo

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Transcription factors associated with SOX4

Gene Symbol Gene ID Gene Info
SOX4
ENSG00000124766.4 SRY-box transcription factor 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_21770078_21770229SOX41760820.035112-0.872.3e-03Click!
chr6_21754115_21754266SOX41601190.041596-0.732.6e-02Click!
chr6_21597329_21597632SOX434090.404139-0.722.9e-02Click!
chr6_21665058_21665374SOX4711450.139838-0.723.0e-02Click!
chr6_21445087_21445238SOX41488100.047465-0.675.0e-02Click!

Activity of the SOX4 motif across conditions

Conditions sorted by the z-value of the SOX4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_40649929_40650165 0.87 MAP3K10
 mitogen-activated protein kinase kinase kinase 10
 47604
 0.08
chr2_204734419_204734570 0.87 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 461
 0.87
chr22_44577668_44577918 0.83 PARVG
 parvin, gamma
 52
 0.99
chr3_108553683_108553877 0.82 TRAT1
 T cell receptor associated transmembrane adaptor 1
 12161
 0.26
chr1_198611164_198611406 0.71 PTPRC
 protein tyrosine phosphatase, receptor type, C
 2993
 0.32
chrY_14081502_14081653 0.60 ENSG00000265161
 .
 134065
 0.06
chr1_99336669_99336925 0.56 RP5-896L10.1
133035
 0.05
chr8_23075544_23076103 0.55 ENSG00000246582
 .
 6161
 0.12
chr4_38802475_38802626 0.55 TLR1
 toll-like receptor 1
 3447
 0.2
chr2_201981847_201982480 0.55 CFLAR
 CASP8 and FADD-like apoptosis regulator
 401
 0.79
chr6_149641931_149642082 0.54 TAB2
 TGF-beta activated kinase 1/MAP3K7 binding protein 2
 182
 0.95
chr19_38539302_38539460 0.53 ENSG00000221258
 .
 5224
 0.2
chr17_38264116_38264342 0.53 NR1D1
 nuclear receptor subfamily 1, group D, member 1
 7251
 0.12
chr12_92524835_92525431 0.51 C12orf79
 chromosome 12 open reading frame 79
 5664
 0.19
chrX_12993326_12993781 0.50 TMSB4X
 thymosin beta 4, X-linked
 190
 0.96
chr12_9911079_9911493 0.50 CD69
 CD69 molecule
 2211
 0.26
chr8_126960397_126960568 0.49 ENSG00000206695
 .
 47287
 0.2
chr4_88310918_88311069 0.49 HSD17B11
 hydroxysteroid (17-beta) dehydrogenase 11
 1308
 0.36
chr20_32993352_32993503 0.48 ENSG00000201498
 .
 21356
 0.13
chr11_88069744_88070033 0.47 CTSC
 cathepsin C
 1013
 0.69
chr4_40202041_40202542 0.47 RHOH
 ras homolog family member H
 327
 0.9
chr2_109605047_109605241 0.46 EDAR
 ectodysplasin A receptor
 581
 0.84
chr9_134145569_134145886 0.46 FAM78A
 family with sequence similarity 78, member A
 153
 0.95
chr12_9912315_9912520 0.45 CD69
 CD69 molecule
 1080
 0.47
chr12_31476387_31476538 0.44 FAM60A
 family with sequence similarity 60, member A
 634
 0.48
chr18_8722090_8722241 0.42 ENSG00000252319
 .
 2035
 0.29
chr1_117296350_117296501 0.42 CD2
 CD2 molecule
 582
 0.78
chr22_17566954_17567330 0.42 IL17RA
 interleukin 17 receptor A
 1293
 0.41
chr22_38789403_38789824 0.40 RP1-5O6.4
4751
 0.14
chrX_77204120_77204271 0.40 PGAM4
 phosphoglycerate mutase family member 4
 20940
 0.16
chr21_34605057_34605328 0.40 IFNAR2
 interferon (alpha, beta and omega) receptor 2
 2478
 0.22
chr17_46504191_46504342 0.40 SKAP1
 src kinase associated phosphoprotein 1
 3286
 0.19
chr12_10019991_10020525 0.40 RP11-290C10.1
632
 0.61
chr11_102192518_102192994 0.40 BIRC3
 baculoviral IAP repeat containing 3
 3196
 0.22
chr5_57787761_57787912 0.39 GAPT
 GRB2-binding adaptor protein, transmembrane
 572
 0.77
chrX_40013569_40013864 0.39 BCOR
 BCL6 corepressor
 7834
 0.32
chr19_4915707_4915936 0.39 ARRDC5
 arrestin domain containing 5
 12942
 0.12
chr11_6766181_6766335 0.39 GVINP1
 GTPase, very large interferon inducible pseudogene 1
 23147
 0.11
chr20_35575234_35575857 0.39 SAMHD1
 SAM domain and HD domain 1
 4566
 0.25
chr20_52196162_52196333 0.39 ZNF217
 zinc finger protein 217
 3389
 0.23
chr17_33861823_33861994 0.39 SLFN12L
 schlafen family member 12-like
 2972
 0.15
chr6_25041553_25042305 0.38 RP3-425P12.5
138
 0.72
chr19_21688467_21688727 0.38 ZNF429
 zinc finger protein 429
 191
 0.96
chr9_95728150_95728303 0.38 FGD3
 FYVE, RhoGEF and PH domain containing 3
 1983
 0.37
chr14_90866152_90866669 0.38 CALM1
 calmodulin 1 (phosphorylase kinase, delta)
 1804
 0.32
chr2_70474548_70475674 0.38 TIA1
 TIA1 cytotoxic granule-associated RNA binding protein
 475
 0.73
chr20_31100174_31100325 0.37 C20orf112
 chromosome 20 open reading frame 112
 1039
 0.53
chr5_90674539_90674690 0.37 ARRDC3
 arrestin domain containing 3
 4562
 0.29
chr17_75447598_75448179 0.37 SEPT9
 septin 9
 562
 0.71
chr6_32479877_32480028 0.37 HLA-DRB5
 major histocompatibility complex, class II, DR beta 5
 18112
 0.13
chrX_74967546_74967697 0.37 MAGEE2
 melanoma antigen family E, 2
 37458
 0.23
chr1_154581072_154581232 0.37 ADAR
 adenosine deaminase, RNA-specific
 470
 0.73
chr8_82022711_82022967 0.37 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 1464
 0.56
chr7_140324480_140324631 0.37 ENSG00000201354
 .
 14908
 0.13
chr2_101916525_101916676 0.36 RNF149
 ring finger protein 149
 8558
 0.17
chr15_40746159_40746352 0.36 RP11-64K12.9
583
 0.57
chr17_73293586_73293836 0.35 SLC25A19
 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
 8120
 0.1
chr3_72788121_72788360 0.35 ENSG00000222838
 .
 47278
 0.17
chr1_1610080_1610231 0.35 RP11-345P4.7
6726
 0.1
chr1_85328555_85328706 0.35 LPAR3
 lysophosphatidic acid receptor 3
 3212
 0.32
chr3_172240144_172241280 0.35 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
 553
 0.83
chr3_166970881_166971032 0.35 ZBBX
 zinc finger, B-box domain containing
 119820
 0.06
chr6_106969857_106970345 0.35 AIM1
 absent in melanoma 1
 10371
 0.2
chr2_54192245_54192396 0.35 ACYP2
 acylphosphatase 2, muscle type
 5655
 0.21
chr20_52205540_52206428 0.35 ZNF217
 zinc finger protein 217
 4394
 0.22
chr7_26141262_26141558 0.35 ENSG00000266430
 .
 41451
 0.15
chr13_48808913_48809219 0.35 ITM2B
 integral membrane protein 2B
 1727
 0.47
chr9_123956593_123956744 0.34 RAB14
 RAB14, member RAS oncogene family
 7479
 0.16
chr18_67624277_67624428 0.34 CD226
 CD226 molecule
 60
 0.99
chr7_55637667_55637921 0.34 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 1767
 0.37
chr1_156784296_156784528 0.34 NTRK1
 neurotrophic tyrosine kinase, receptor, type 1
 1036
 0.37
chr4_37853129_37853280 0.34 PGM2
 phosphoglucomutase 2
 24861
 0.21
chr6_18390846_18390997 0.34 RNF144B
 ring finger protein 144B
 3340
 0.27
chr1_185126672_185127282 0.34 SWT1
 SWT1 RNA endoribonuclease homolog (S. cerevisiae)
 363
 0.75
chr7_150180608_150181504 0.33 GIMAP7
 GTPase, IMAP family member 7
 30862
 0.13
chr4_153194568_153194863 0.33 ENSG00000244544
 .
 9118
 0.23
chr1_167737420_167737571 0.33 MPZL1
 myelin protein zero-like 1
 2688
 0.33
chr2_37934077_37934228 0.33 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
 31459
 0.22
chr19_42056498_42056882 0.33 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 804
 0.6
chr1_89736462_89736619 0.33 GBP5
 guanylate binding protein 5
 6
 0.98
chr2_118943251_118943914 0.33 INSIG2
 insulin induced gene 2
 97532
 0.08
chr12_65107167_65107318 0.33 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 16913
 0.13
chr20_43599555_43599726 0.33 STK4
 serine/threonine kinase 4
 4473
 0.17
chr12_10282570_10282865 0.33 CLEC7A
 C-type lectin domain family 7, member A
 35
 0.96
chr7_74990498_74990649 0.32 STAG3L1
 stromal antigen 3-like 1 (pseudogene)
 71
 0.95
chr1_160766044_160766224 0.32 LY9
 lymphocyte antigen 9
 157
 0.95
chr16_88846750_88847135 0.32 PIEZO1
 piezo-type mechanosensitive ion channel component 1
 4677
 0.1
chr7_50345445_50345596 0.32 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 1142
 0.64
chr14_75229834_75229985 0.32 YLPM1
 YLP motif containing 1
 160
 0.95
chr19_918011_918162 0.32 KISS1R
 KISS1 receptor
 583
 0.52
chr7_157280857_157281149 0.32 AC006372.6
24985
 0.19
chr8_24961478_24961629 0.31 ENSG00000241811
 .
 77682
 0.1
chr9_5627180_5627331 0.31 KIAA1432
 KIAA1432
 1770
 0.46
chr4_56814187_56814608 0.31 CEP135
 centrosomal protein 135kDa
 640
 0.74
chrX_118825016_118825167 0.31 SEPT6
 septin 6
 1701
 0.35
chr6_24930325_24930476 0.31 FAM65B
 family with sequence similarity 65, member B
 5788
 0.25
chr10_6585169_6585583 0.31 PRKCQ
 protein kinase C, theta
 36825
 0.22
chr20_43598945_43599305 0.31 STK4
 serine/threonine kinase 4
 3958
 0.17
chr5_56473598_56474064 0.31 GPBP1
 GC-rich promoter binding protein 1
 2058
 0.37
chr18_21574432_21574665 0.31 TTC39C
 tetratricopeptide repeat domain 39C
 1811
 0.34
chr1_239883177_239883989 0.31 CHRM3
 cholinergic receptor, muscarinic 3
 740
 0.59
chr20_47400149_47400300 0.30 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 44196
 0.16
chr15_45006518_45006669 0.30 B2M
 beta-2-microglobulin
 2878
 0.2
chr2_113032580_113032916 0.30 ZC3H6
 zinc finger CCCH-type containing 6
 423
 0.83
chr7_17442118_17442269 0.30 ENSG00000199473
 .
 29243
 0.23
chr6_113952132_113952371 0.30 ENSG00000266650
 .
 28134
 0.22
chr10_28622520_28622887 0.30 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
 712
 0.72
chr14_21948291_21948442 0.30 TOX4
 TOX high mobility group box family member 4
 2983
 0.15
chr2_234265937_234266088 0.30 DGKD
 diacylglycerol kinase, delta 130kDa
 2858
 0.2
chr11_5246641_5246814 0.30 ENSG00000221031
 .
 858
 0.32
chr1_111212990_111213454 0.30 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 4433
 0.21
chr3_30652267_30652444 0.29 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 4262
 0.34
chr19_12722754_12723067 0.29 ZNF791
 zinc finger protein 791
 1142
 0.25
chr9_92079396_92079574 0.29 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 8617
 0.24
chr8_28918430_28918927 0.29 CTD-2647L4.4
5226
 0.15
chr17_61784124_61784275 0.29 STRADA
 STE20-related kinase adaptor alpha
 2384
 0.23
chr2_216866271_216866422 0.29 MREG
 melanoregulin
 12000
 0.24
chr1_65428244_65428470 0.29 JAK1
 Janus kinase 1
 3830
 0.29
chr17_49340271_49340434 0.29 UTP18
 UTP18 small subunit (SSU) processome component homolog (yeast)
 2463
 0.24
chr10_22625053_22625204 0.29 SPAG6
 sperm associated antigen 6
 9271
 0.15
chr12_69080140_69080577 0.29 NUP107
 nucleoporin 107kDa
 156
 0.96
chr3_187637243_187637630 0.29 BCL6
 B-cell CLL/lymphoma 6
 173921
 0.03
chrY_1605029_1605190 0.29 NA
 NA
 > 106
 NA
chr2_198161068_198161358 0.29 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 6030
 0.18
chr1_25060751_25060902 0.29 CLIC4
 chloride intracellular channel 4
 11022
 0.2
chr10_112326670_112327053 0.29 SMC3
 structural maintenance of chromosomes 3
 588
 0.72
chr12_8000847_8001105 0.29 ENSG00000222978
 .
 1092
 0.36
chr6_139458021_139458384 0.29 HECA
 headcase homolog (Drosophila)
 1953
 0.43
chr5_80444015_80444393 0.28 CTD-2193P3.2
33533
 0.2
chrX_1655035_1655190 0.28 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 888
 0.64
chr1_150738028_150738252 0.28 CTSS
 cathepsin S
 128
 0.95
chr5_96232398_96232549 0.28 ERAP2
 endoplasmic reticulum aminopeptidase 2
 7552
 0.17
chr10_3989446_3989597 0.28 KLF6
 Kruppel-like factor 6
 162048
 0.04
chr14_69281480_69282477 0.28 ZFP36L1
 ZFP36 ring finger protein-like 1
 18788
 0.19
chr7_72474255_72474406 0.28 STAG3L3
 stromal antigen 3-like 3
 77
 0.94
chr12_40012002_40012194 0.28 ABCD2
 ATP-binding cassette, sub-family D (ALD), member 2
 1455
 0.48
chr14_94596078_94596470 0.28 IFI27L2
 interferon, alpha-inducible protein 27-like 2
 273
 0.89
chr1_109757024_109757692 0.28 SARS
 seryl-tRNA synthetase
 754
 0.58
chr1_214776783_214777161 0.28 CENPF
 centromere protein F, 350/400kDa
 434
 0.9
chr7_78902475_78902626 0.28 ENSG00000212482
 .
 70138
 0.13
chr17_37027113_37027349 0.27 LASP1
 LIM and SH3 protein 1
 835
 0.41
chr5_178961569_178961720 0.27 RUFY1
 RUN and FYVE domain containing 1
 15915
 0.18
chr9_92108724_92108875 0.27 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 3548
 0.27
chr12_50794251_50794599 0.27 LARP4
 La ribonucleoprotein domain family, member 4
 167
 0.95
chr12_11803298_11803449 0.27 ETV6
 ets variant 6
 585
 0.83
chr5_66125758_66126173 0.27 MAST4
 microtubule associated serine/threonine kinase family member 4
 1275
 0.63
chr6_13709524_13709675 0.27 RANBP9
 RAN binding protein 9
 2197
 0.32
chr14_71466281_71466432 0.27 PCNX
 pecanex homolog (Drosophila)
 13392
 0.29
chr11_12886271_12886427 0.27 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 14641
 0.16
chr4_70625524_70625675 0.27 SULT1B1
 sulfotransferase family, cytosolic, 1B, member 1
 717
 0.76
chr16_9038174_9038325 0.27 USP7
 ubiquitin specific peptidase 7 (herpes virus-associated)
 7663
 0.21
chr14_50988685_50989139 0.27 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
 10278
 0.18
chr9_133793888_133794039 0.27 FIBCD1
 fibrinogen C domain containing 1
 11403
 0.17
chr6_1162897_1163107 0.27 ENSG00000238438
 .
 23751
 0.25
chr2_106777289_106777491 0.27 UXS1
 UDP-glucuronate decarboxylase 1
 309
 0.92
chr6_170862470_170862790 0.27 PSMB1
 proteasome (prosome, macropain) subunit, beta type, 1
 201
 0.86
chr8_134070006_134070389 0.27 SLA
 Src-like-adaptor
 2406
 0.36
chr17_55372937_55373088 0.27 MSI2
 musashi RNA-binding protein 2
 966
 0.68
chr7_74304507_74304707 0.27 STAG3L2
 stromal antigen 3-like 2 (pseudogene)
 89
 0.97
chr11_85773706_85774153 0.27 PICALM
 phosphatidylinositol binding clathrin assembly protein
 5893
 0.24
chr7_77038696_77038897 0.27 GSAP
 gamma-secretase activating protein
 6388
 0.24
chr1_144491287_144491477 0.27 ENSG00000206828
 .
 223
 0.63
chr16_30158399_30158550 0.27 MAPK3
 mitogen-activated protein kinase 3
 23647
 0.07
chr14_77924100_77924339 0.26 AHSA1
 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
 6
 0.75
chr1_144311048_144311246 0.26 ENSG00000207106
 .
 229
 0.94
chr15_78344938_78345089 0.26 TBC1D2B
 TBC1 domain family, member 2B
 13452
 0.12
chr17_45725211_45725362 0.26 RP11-580I16.2
1482
 0.26
chr2_158295494_158296053 0.26 CYTIP
 cytohesin 1 interacting protein
 153
 0.96
chr17_58441116_58441273 0.26 USP32
 ubiquitin specific peptidase 32
 28142
 0.18
chr8_142231340_142231491 0.26 SLC45A4
 solute carrier family 45, member 4
 7254
 0.16
chr8_70745749_70746362 0.26 RP11-159H10.3
291
 0.62
chr18_34953359_34953510 0.26 RP11-797E24.3
99011
 0.08
chr12_113494960_113495179 0.25 DTX1
 deltex homolog 1 (Drosophila)
 426
 0.82
chr8_22524109_22524260 0.25 BIN3
 bridging integrator 3
 2442
 0.18
chr9_123689156_123689307 0.25 TRAF1
 TNF receptor-associated factor 1
 1816
 0.39
chr16_86530318_86530469 0.25 FOXF1
 forkhead box F1
 13740
 0.21
chr5_68338922_68339492 0.25 SLC30A5
 solute carrier family 30 (zinc transporter), member 5
 50266
 0.12
chr8_39797291_39797650 0.25 IDO2
 indoleamine 2,3-dioxygenase 2
 4996
 0.18
chr19_9434639_9434796 0.25 ZNF559-ZNF177
 ZNF559-ZNF177 readthrough
 133
 0.42
chr13_73942671_73942822 0.25 ENSG00000206697
 .
 141462
 0.05
chr12_14538796_14538963 0.25 ATF7IP
 activating transcription factor 7 interacting protein
 881
 0.68
chr15_81588845_81588996 0.25 IL16
 interleukin 16
 334
 0.89
chr6_95345075_95345226 0.25 MANEA-AS1
 MANEA antisense RNA 1 (head to head)
 680176
 0.0
chr5_35859258_35859647 0.25 IL7R
 interleukin 7 receptor
 2458
 0.3
chr3_141104822_141105076 0.25 ZBTB38
 zinc finger and BTB domain containing 38
 345
 0.9
chr6_24926129_24926280 0.25 FAM65B
 family with sequence similarity 65, member B
 9984
 0.23
chr3_128839009_128839399 0.25 RAB43
 RAB43, member RAS oncogene family
 1420
 0.29
chr15_90134992_90135143 0.25 RP11-429B14.3
9539
 0.15
chr19_10362356_10362534 0.25 MRPL4
 mitochondrial ribosomal protein L4
 132
 0.9
chr4_149297049_149297674 0.25 NR3C2
 nuclear receptor subfamily 3, group C, member 2
 60651
 0.16
chr9_139433599_139433867 0.25 RP11-413M3.4
3600
 0.12
chrX_39965904_39966415 0.24 BCOR
 BCL6 corepressor
 9503
 0.31
chr6_35568962_35570321 0.24 ENSG00000212579
 .
 49954
 0.1
chr1_115054290_115054442 0.24 TRIM33
 tripartite motif containing 33
 585
 0.78
chr11_59320728_59320879 0.24 ENSG00000252893
 .
 5470
 0.14
chr8_29908813_29909180 0.24 ENSG00000239175
 .
 7572
 0.17
chr12_8113539_8113794 0.24 ENSG00000206636
 .
 15189
 0.15
chr5_56116454_56116605 0.24 MAP3K1
 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
 5128
 0.21
chr21_44465977_44466220 0.24 CBS
 cystathionine-beta-synthase
 12953
 0.18
chr5_131757138_131757303 0.24 AC116366.5
4926
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.5 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.5 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.2 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.3 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.4 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.3 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.2 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.3 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.4 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0046398 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.3 GO:0007099 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.1 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:1904238 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0002669 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.4 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.2 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0071028 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.2 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0014010 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0 0.1 GO:0090201 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) regulation of apoptotic process involved in morphogenesis(GO:1902337) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) regulation of apoptotic process involved in development(GO:1904748)
0.0 0.0 GO:0043486 histone exchange(GO:0043486)
0.0 0.0 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.2 GO:0001504 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0036230 granulocyte activation(GO:0036230)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:1903311 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.0 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821) histamine transport(GO:0051608)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.9 GO:0051168 nuclear export(GO:0051168)
0.0 1.4 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0038061 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0 0.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0001846 opsonin binding(GO:0001846)
0.1 0.3 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0045502 dynein binding(GO:0045502)
0.1 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.0 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.0 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314) phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.0 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.0 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10