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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SOX4

Z-value: 1.30

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Transcription factors associated with SOX4

Gene Symbol	Gene ID	Gene Info
SOX4 Ensembl NCBI GeneCards UniProt	ENSG00000124766.4	SOX4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SOX4	chr6_21770078_21770229	176082	0.035112	-0.87	2.3e-03	Click!
SOX4	chr6_21754115_21754266	160119	0.041596	-0.73	2.6e-02	Click!
SOX4	chr6_21597329_21597632	3409	0.404139	-0.72	2.9e-02	Click!
SOX4	chr6_21665058_21665374	71145	0.139838	-0.72	3.0e-02	Click!
SOX4	chr6_21445087_21445238	148810	0.047465	-0.67	5.0e-02	Click!

Activity of the SOX4 motif across conditions

Conditions sorted by the z-value of the SOX4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_40649929_40650165	0.87	MAP3K10	mitogen-activated protein kinase kinase kinase 10	47604	0.08
chr2_204734419_204734570	0.87	CTLA4	cytotoxic T-lymphocyte-associated protein 4	461	0.87
chr22_44577668_44577918	0.83	PARVG	parvin, gamma	52	0.99
chr3_108553683_108553877	0.82	TRAT1	T cell receptor associated transmembrane adaptor 1	12161	0.26
chr1_198611164_198611406	0.71	PTPRC	protein tyrosine phosphatase, receptor type, C	2993	0.32
chrY_14081502_14081653	0.60	ENSG00000265161	.	134065	0.06
chr1_99336669_99336925	0.56	RP5-896L10.1		133035	0.05
chr8_23075544_23076103	0.55	ENSG00000246582	.	6161	0.12
chr4_38802475_38802626	0.55	TLR1	toll-like receptor 1	3447	0.2
chr2_201981847_201982480	0.55	CFLAR	CASP8 and FADD-like apoptosis regulator	401	0.79
chr6_149641931_149642082	0.54	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	182	0.95
chr19_38539302_38539460	0.53	ENSG00000221258	.	5224	0.2
chr17_38264116_38264342	0.53	NR1D1	nuclear receptor subfamily 1, group D, member 1	7251	0.12
chr12_92524835_92525431	0.51	C12orf79	chromosome 12 open reading frame 79	5664	0.19
chrX_12993326_12993781	0.50	TMSB4X	thymosin beta 4, X-linked	190	0.96
chr12_9911079_9911493	0.50	CD69	CD69 molecule	2211	0.26
chr8_126960397_126960568	0.49	ENSG00000206695	.	47287	0.2
chr4_88310918_88311069	0.49	HSD17B11	hydroxysteroid (17-beta) dehydrogenase 11	1308	0.36
chr20_32993352_32993503	0.48	ENSG00000201498	.	21356	0.13
chr11_88069744_88070033	0.47	CTSC	cathepsin C	1013	0.69
chr4_40202041_40202542	0.47	RHOH	ras homolog family member H	327	0.9
chr2_109605047_109605241	0.46	EDAR	ectodysplasin A receptor	581	0.84
chr9_134145569_134145886	0.46	FAM78A	family with sequence similarity 78, member A	153	0.95
chr12_9912315_9912520	0.45	CD69	CD69 molecule	1080	0.47
chr12_31476387_31476538	0.44	FAM60A	family with sequence similarity 60, member A	634	0.48
chr18_8722090_8722241	0.42	ENSG00000252319	.	2035	0.29
chr1_117296350_117296501	0.42	CD2	CD2 molecule	582	0.78
chr22_17566954_17567330	0.42	IL17RA	interleukin 17 receptor A	1293	0.41
chr22_38789403_38789824	0.40	RP1-5O6.4		4751	0.14
chrX_77204120_77204271	0.40	PGAM4	phosphoglycerate mutase family member 4	20940	0.16
chr21_34605057_34605328	0.40	IFNAR2	interferon (alpha, beta and omega) receptor 2	2478	0.22
chr17_46504191_46504342	0.40	SKAP1	src kinase associated phosphoprotein 1	3286	0.19
chr12_10019991_10020525	0.40	RP11-290C10.1		632	0.61
chr11_102192518_102192994	0.40	BIRC3	baculoviral IAP repeat containing 3	3196	0.22
chr5_57787761_57787912	0.39	GAPT	GRB2-binding adaptor protein, transmembrane	572	0.77
chrX_40013569_40013864	0.39	BCOR	BCL6 corepressor	7834	0.32
chr19_4915707_4915936	0.39	ARRDC5	arrestin domain containing 5	12942	0.12
chr11_6766181_6766335	0.39	GVINP1	GTPase, very large interferon inducible pseudogene 1	23147	0.11
chr20_35575234_35575857	0.39	SAMHD1	SAM domain and HD domain 1	4566	0.25
chr20_52196162_52196333	0.39	ZNF217	zinc finger protein 217	3389	0.23
chr17_33861823_33861994	0.39	SLFN12L	schlafen family member 12-like	2972	0.15
chr6_25041553_25042305	0.38	RP3-425P12.5		138	0.72
chr19_21688467_21688727	0.38	ZNF429	zinc finger protein 429	191	0.96
chr9_95728150_95728303	0.38	FGD3	FYVE, RhoGEF and PH domain containing 3	1983	0.37
chr14_90866152_90866669	0.38	CALM1	calmodulin 1 (phosphorylase kinase, delta)	1804	0.32
chr2_70474548_70475674	0.38	TIA1	TIA1 cytotoxic granule-associated RNA binding protein	475	0.73
chr20_31100174_31100325	0.37	C20orf112	chromosome 20 open reading frame 112	1039	0.53
chr5_90674539_90674690	0.37	ARRDC3	arrestin domain containing 3	4562	0.29
chr17_75447598_75448179	0.37	SEPT9	septin 9	562	0.71
chr6_32479877_32480028	0.37	HLA-DRB5	major histocompatibility complex, class II, DR beta 5	18112	0.13
chrX_74967546_74967697	0.37	MAGEE2	melanoma antigen family E, 2	37458	0.23
chr1_154581072_154581232	0.37	ADAR	adenosine deaminase, RNA-specific	470	0.73
chr8_82022711_82022967	0.37	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	1464	0.56
chr7_140324480_140324631	0.37	ENSG00000201354	.	14908	0.13
chr2_101916525_101916676	0.36	RNF149	ring finger protein 149	8558	0.17
chr15_40746159_40746352	0.36	RP11-64K12.9		583	0.57
chr17_73293586_73293836	0.35	SLC25A19	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19	8120	0.1
chr3_72788121_72788360	0.35	ENSG00000222838	.	47278	0.17
chr1_1610080_1610231	0.35	RP11-345P4.7		6726	0.1
chr1_85328555_85328706	0.35	LPAR3	lysophosphatidic acid receptor 3	3212	0.32
chr3_172240144_172241280	0.35	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	553	0.83
chr3_166970881_166971032	0.35	ZBBX	zinc finger, B-box domain containing	119820	0.06
chr6_106969857_106970345	0.35	AIM1	absent in melanoma 1	10371	0.2
chr2_54192245_54192396	0.35	ACYP2	acylphosphatase 2, muscle type	5655	0.21
chr20_52205540_52206428	0.35	ZNF217	zinc finger protein 217	4394	0.22
chr7_26141262_26141558	0.35	ENSG00000266430	.	41451	0.15
chr13_48808913_48809219	0.35	ITM2B	integral membrane protein 2B	1727	0.47
chr9_123956593_123956744	0.34	RAB14	RAB14, member RAS oncogene family	7479	0.16
chr18_67624277_67624428	0.34	CD226	CD226 molecule	60	0.99
chr7_55637667_55637921	0.34	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	1767	0.37
chr1_156784296_156784528	0.34	NTRK1	neurotrophic tyrosine kinase, receptor, type 1	1036	0.37
chr4_37853129_37853280	0.34	PGM2	phosphoglucomutase 2	24861	0.21
chr6_18390846_18390997	0.34	RNF144B	ring finger protein 144B	3340	0.27
chr1_185126672_185127282	0.34	SWT1	SWT1 RNA endoribonuclease homolog (S. cerevisiae)	363	0.75
chr7_150180608_150181504	0.33	GIMAP7	GTPase, IMAP family member 7	30862	0.13
chr4_153194568_153194863	0.33	ENSG00000244544	.	9118	0.23
chr1_167737420_167737571	0.33	MPZL1	myelin protein zero-like 1	2688	0.33
chr2_37934077_37934228	0.33	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	31459	0.22
chr19_42056498_42056882	0.33	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	804	0.6
chr1_89736462_89736619	0.33	GBP5	guanylate binding protein 5	6	0.98
chr2_118943251_118943914	0.33	INSIG2	insulin induced gene 2	97532	0.08
chr12_65107167_65107318	0.33	AC025262.1	Mesenchymal stem cell protein DSC96; Uncharacterized protein	16913	0.13
chr20_43599555_43599726	0.33	STK4	serine/threonine kinase 4	4473	0.17
chr12_10282570_10282865	0.33	CLEC7A	C-type lectin domain family 7, member A	35	0.96
chr7_74990498_74990649	0.32	STAG3L1	stromal antigen 3-like 1 (pseudogene)	71	0.95
chr1_160766044_160766224	0.32	LY9	lymphocyte antigen 9	157	0.95
chr16_88846750_88847135	0.32	PIEZO1	piezo-type mechanosensitive ion channel component 1	4677	0.1
chr7_50345445_50345596	0.32	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1142	0.64
chr14_75229834_75229985	0.32	YLPM1	YLP motif containing 1	160	0.95
chr19_918011_918162	0.32	KISS1R	KISS1 receptor	583	0.52
chr7_157280857_157281149	0.32	AC006372.6		24985	0.19
chr8_24961478_24961629	0.31	ENSG00000241811	.	77682	0.1
chr9_5627180_5627331	0.31	KIAA1432	KIAA1432	1770	0.46
chr4_56814187_56814608	0.31	CEP135	centrosomal protein 135kDa	640	0.74
chrX_118825016_118825167	0.31	SEPT6	septin 6	1701	0.35
chr6_24930325_24930476	0.31	FAM65B	family with sequence similarity 65, member B	5788	0.25
chr10_6585169_6585583	0.31	PRKCQ	protein kinase C, theta	36825	0.22
chr20_43598945_43599305	0.31	STK4	serine/threonine kinase 4	3958	0.17
chr5_56473598_56474064	0.31	GPBP1	GC-rich promoter binding protein 1	2058	0.37
chr18_21574432_21574665	0.31	TTC39C	tetratricopeptide repeat domain 39C	1811	0.34
chr1_239883177_239883989	0.31	CHRM3	cholinergic receptor, muscarinic 3	740	0.59
chr20_47400149_47400300	0.30	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	44196	0.16
chr15_45006518_45006669	0.30	B2M	beta-2-microglobulin	2878	0.2
chr2_113032580_113032916	0.30	ZC3H6	zinc finger CCCH-type containing 6	423	0.83
chr7_17442118_17442269	0.30	ENSG00000199473	.	29243	0.23
chr6_113952132_113952371	0.30	ENSG00000266650	.	28134	0.22
chr10_28622520_28622887	0.30	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	712	0.72
chr14_21948291_21948442	0.30	TOX4	TOX high mobility group box family member 4	2983	0.15
chr2_234265937_234266088	0.30	DGKD	diacylglycerol kinase, delta 130kDa	2858	0.2
chr11_5246641_5246814	0.30	ENSG00000221031	.	858	0.32
chr1_111212990_111213454	0.30	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	4433	0.21
chr3_30652267_30652444	0.29	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	4262	0.34
chr19_12722754_12723067	0.29	ZNF791	zinc finger protein 791	1142	0.25
chr9_92079396_92079574	0.29	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	8617	0.24
chr8_28918430_28918927	0.29	CTD-2647L4.4		5226	0.15
chr17_61784124_61784275	0.29	STRADA	STE20-related kinase adaptor alpha	2384	0.23
chr2_216866271_216866422	0.29	MREG	melanoregulin	12000	0.24
chr1_65428244_65428470	0.29	JAK1	Janus kinase 1	3830	0.29
chr17_49340271_49340434	0.29	UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)	2463	0.24
chr10_22625053_22625204	0.29	SPAG6	sperm associated antigen 6	9271	0.15
chr12_69080140_69080577	0.29	NUP107	nucleoporin 107kDa	156	0.96
chr3_187637243_187637630	0.29	BCL6	B-cell CLL/lymphoma 6	173921	0.03
chrY_1605029_1605190	0.29	NA	NA	> 10⁶	NA
chr2_198161068_198161358	0.29	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	6030	0.18
chr1_25060751_25060902	0.29	CLIC4	chloride intracellular channel 4	11022	0.2
chr10_112326670_112327053	0.29	SMC3	structural maintenance of chromosomes 3	588	0.72
chr12_8000847_8001105	0.29	ENSG00000222978	.	1092	0.36
chr6_139458021_139458384	0.29	HECA	headcase homolog (Drosophila)	1953	0.43
chr5_80444015_80444393	0.28	CTD-2193P3.2		33533	0.2
chrX_1655035_1655190	0.28	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	888	0.64
chr1_150738028_150738252	0.28	CTSS	cathepsin S	128	0.95
chr5_96232398_96232549	0.28	ERAP2	endoplasmic reticulum aminopeptidase 2	7552	0.17
chr10_3989446_3989597	0.28	KLF6	Kruppel-like factor 6	162048	0.04
chr14_69281480_69282477	0.28	ZFP36L1	ZFP36 ring finger protein-like 1	18788	0.19
chr7_72474255_72474406	0.28	STAG3L3	stromal antigen 3-like 3	77	0.94
chr12_40012002_40012194	0.28	ABCD2	ATP-binding cassette, sub-family D (ALD), member 2	1455	0.48
chr14_94596078_94596470	0.28	IFI27L2	interferon, alpha-inducible protein 27-like 2	273	0.89
chr1_109757024_109757692	0.28	SARS	seryl-tRNA synthetase	754	0.58
chr1_214776783_214777161	0.28	CENPF	centromere protein F, 350/400kDa	434	0.9
chr7_78902475_78902626	0.28	ENSG00000212482	.	70138	0.13
chr17_37027113_37027349	0.27	LASP1	LIM and SH3 protein 1	835	0.41
chr5_178961569_178961720	0.27	RUFY1	RUN and FYVE domain containing 1	15915	0.18
chr9_92108724_92108875	0.27	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	3548	0.27
chr12_50794251_50794599	0.27	LARP4	La ribonucleoprotein domain family, member 4	167	0.95
chr12_11803298_11803449	0.27	ETV6	ets variant 6	585	0.83
chr5_66125758_66126173	0.27	MAST4	microtubule associated serine/threonine kinase family member 4	1275	0.63
chr6_13709524_13709675	0.27	RANBP9	RAN binding protein 9	2197	0.32
chr14_71466281_71466432	0.27	PCNX	pecanex homolog (Drosophila)	13392	0.29
chr11_12886271_12886427	0.27	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	14641	0.16
chr4_70625524_70625675	0.27	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	717	0.76
chr16_9038174_9038325	0.27	USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	7663	0.21
chr14_50988685_50989139	0.27	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	10278	0.18
chr9_133793888_133794039	0.27	FIBCD1	fibrinogen C domain containing 1	11403	0.17
chr6_1162897_1163107	0.27	ENSG00000238438	.	23751	0.25
chr2_106777289_106777491	0.27	UXS1	UDP-glucuronate decarboxylase 1	309	0.92
chr6_170862470_170862790	0.27	PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	201	0.86
chr8_134070006_134070389	0.27	SLA	Src-like-adaptor	2406	0.36
chr17_55372937_55373088	0.27	MSI2	musashi RNA-binding protein 2	966	0.68
chr7_74304507_74304707	0.27	STAG3L2	stromal antigen 3-like 2 (pseudogene)	89	0.97
chr11_85773706_85774153	0.27	PICALM	phosphatidylinositol binding clathrin assembly protein	5893	0.24
chr7_77038696_77038897	0.27	GSAP	gamma-secretase activating protein	6388	0.24
chr1_144491287_144491477	0.27	ENSG00000206828	.	223	0.63
chr16_30158399_30158550	0.27	MAPK3	mitogen-activated protein kinase 3	23647	0.07
chr14_77924100_77924339	0.26	AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	6	0.75
chr1_144311048_144311246	0.26	ENSG00000207106	.	229	0.94
chr15_78344938_78345089	0.26	TBC1D2B	TBC1 domain family, member 2B	13452	0.12
chr17_45725211_45725362	0.26	RP11-580I16.2		1482	0.26
chr2_158295494_158296053	0.26	CYTIP	cytohesin 1 interacting protein	153	0.96
chr17_58441116_58441273	0.26	USP32	ubiquitin specific peptidase 32	28142	0.18
chr8_142231340_142231491	0.26	SLC45A4	solute carrier family 45, member 4	7254	0.16
chr8_70745749_70746362	0.26	RP11-159H10.3		291	0.62
chr18_34953359_34953510	0.26	RP11-797E24.3		99011	0.08
chr12_113494960_113495179	0.25	DTX1	deltex homolog 1 (Drosophila)	426	0.82
chr8_22524109_22524260	0.25	BIN3	bridging integrator 3	2442	0.18
chr9_123689156_123689307	0.25	TRAF1	TNF receptor-associated factor 1	1816	0.39
chr16_86530318_86530469	0.25	FOXF1	forkhead box F1	13740	0.21
chr5_68338922_68339492	0.25	SLC30A5	solute carrier family 30 (zinc transporter), member 5	50266	0.12
chr8_39797291_39797650	0.25	IDO2	indoleamine 2,3-dioxygenase 2	4996	0.18
chr19_9434639_9434796	0.25	ZNF559-ZNF177	ZNF559-ZNF177 readthrough	133	0.42
chr13_73942671_73942822	0.25	ENSG00000206697	.	141462	0.05
chr12_14538796_14538963	0.25	ATF7IP	activating transcription factor 7 interacting protein	881	0.68
chr15_81588845_81588996	0.25	IL16	interleukin 16	334	0.89
chr6_95345075_95345226	0.25	MANEA-AS1	MANEA antisense RNA 1 (head to head)	680176	0.0
chr5_35859258_35859647	0.25	IL7R	interleukin 7 receptor	2458	0.3
chr3_141104822_141105076	0.25	ZBTB38	zinc finger and BTB domain containing 38	345	0.9
chr6_24926129_24926280	0.25	FAM65B	family with sequence similarity 65, member B	9984	0.23
chr3_128839009_128839399	0.25	RAB43	RAB43, member RAS oncogene family	1420	0.29
chr15_90134992_90135143	0.25	RP11-429B14.3		9539	0.15
chr19_10362356_10362534	0.25	MRPL4	mitochondrial ribosomal protein L4	132	0.9
chr4_149297049_149297674	0.25	NR3C2	nuclear receptor subfamily 3, group C, member 2	60651	0.16
chr9_139433599_139433867	0.25	RP11-413M3.4		3600	0.12
chrX_39965904_39966415	0.24	BCOR	BCL6 corepressor	9503	0.31
chr6_35568962_35570321	0.24	ENSG00000212579	.	49954	0.1
chr1_115054290_115054442	0.24	TRIM33	tripartite motif containing 33	585	0.78
chr11_59320728_59320879	0.24	ENSG00000252893	.	5470	0.14
chr8_29908813_29909180	0.24	ENSG00000239175	.	7572	0.17
chr12_8113539_8113794	0.24	ENSG00000206636	.	15189	0.15
chr5_56116454_56116605	0.24	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	5128	0.21
chr21_44465977_44466220	0.24	CBS	cystathionine-beta-synthase	12953	0.18
chr5_131757138_131757303	0.24	AC116366.5		4926	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.5	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.5	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.3	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.3	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.3	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.3	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.2	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.4	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.1	0.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.2	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.3	GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.2	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.3	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.3	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.4	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.2	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0046398	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.4	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.3	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.1	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:1904238	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.4	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.3	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.4	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.2	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.3	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0071028	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.2	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0014010	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0	0.1	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.1	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
0.0	0.1	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.2	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.2	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) regulation of apoptotic process involved in morphogenesis(GO:1902337) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) regulation of apoptotic process involved in development(GO:1904748)
0.0	0.0	GO:0043486	histone exchange(GO:0043486)
0.0	0.0	GO:2000757	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.0	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.1	GO:0034227	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	1.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.5	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.2	GO:0001504	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.4	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0060968	regulation of gene silencing(GO:0060968)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:1903311	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0	0.1	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.0	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821) histamine transport(GO:0051608)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.9	GO:0051168	nuclear export(GO:0051168)
0.0	1.4	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.0	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.3	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0038061	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0	0.0	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.7	GO:0005844	polysome(GO:0005844)
0.0	0.2	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.5	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.9	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.7	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.3	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.7	GO:0000786	nucleosome(GO:0000786)
0.0	0.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.2	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.3	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.3	GO:0001846	opsonin binding(GO:0001846)
0.1	0.3	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.5	GO:0045502	dynein binding(GO:0045502)
0.1	0.2	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.2	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.0	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.5	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	1.2	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.4	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.5	GO:0003823	antigen binding(GO:0003823)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.0	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.0	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.7	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.4	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.0	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.0	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314) phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.9	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.5	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.9	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.2	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.5	PID ATM PATHWAY	ATM pathway
0.0	0.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.4	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.0	PID FOXO PATHWAY	FoxO family signaling
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.5	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.9	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	1.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.0	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.3	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10