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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for SOX5

Z-value: 1.18

Motif logo

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Transcription factors associated with SOX5

Gene Symbol Gene ID Gene Info
SOX5
ENSG00000134532.11 SRY-box transcription factor 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_24102871_24103025SOX53110.9489130.703.7e-02Click!
chr12_24103066_24103383SOX55870.8640930.655.8e-02Click!
chr12_24102324_24102475SOX51820.9751630.655.9e-02Click!
chr12_24199012_24199210SOX5951450.0928010.627.3e-02Click!
chr12_24048929_24049080SOX5430.9889420.521.5e-01Click!

Activity of the SOX5 motif across conditions

Conditions sorted by the z-value of the SOX5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_114714851_114715858 0.43 RP11-57H14.2
3720
 0.26
chr11_131780761_131781452 0.36 NTM
 neurotrimin
 209
 0.95
chr4_55095719_55096018 0.35 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
 142
 0.98
chr6_27584810_27585278 0.33 ENSG00000238648
 .
 14144
 0.19
chr8_19148668_19149118 0.33 SH2D4A
 SH2 domain containing 4A
 22235
 0.28
chr15_49716260_49716444 0.31 FGF7
 fibroblast growth factor 7
 895
 0.66
chr2_189839524_189839773 0.31 COL3A1
 collagen, type III, alpha 1
 549
 0.79
chr3_87036535_87037613 0.29 VGLL3
 vestigial like 3 (Drosophila)
 2778
 0.42
chr7_93552303_93552503 0.28 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
 1392
 0.38
chr7_19155713_19156221 0.28 TWIST1
 twist family bHLH transcription factor 1
 1328
 0.36
chr18_31157392_31158104 0.27 ASXL3
 additional sex combs like 3 (Drosophila)
 848
 0.76
chr8_142289533_142290316 0.27 RP11-10J21.3
 Uncharacterized protein
 25260
 0.12
chr2_189841718_189841869 0.26 ENSG00000221502
 .
 1025
 0.55
chr1_178064247_178064419 0.25 RASAL2
 RAS protein activator like 2
 1057
 0.69
chr2_9815742_9816384 0.23 YWHAQ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
 44920
 0.13
chr11_121964934_121965228 0.23 ENSG00000207971
 .
 5471
 0.18
chr9_133656128_133656348 0.23 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 54215
 0.13
chr1_172110530_172111247 0.23 ENSG00000207949
 .
 2841
 0.22
chr7_127307743_127307970 0.22 SND1
 staphylococcal nuclease and tudor domain containing 1
 15622
 0.17
chr11_121800761_121801203 0.22 ENSG00000252556
 .
 74081
 0.11
chr5_134825154_134825603 0.22 TIFAB
 TRAF-interacting protein with forkhead-associated domain, family member B
 37289
 0.11
chr10_69831641_69832005 0.21 HERC4
 HECT and RLD domain containing E3 ubiquitin protein ligase 4
 2071
 0.33
chr11_9548903_9549060 0.21 ZNF143
 zinc finger protein 143
 14937
 0.16
chr6_85482826_85483217 0.21 TBX18
 T-box 18
 8784
 0.3
chr4_159093168_159093728 0.21 RP11-597D13.9
281
 0.64
chr9_22008020_22008450 0.20 CDKN2B
 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
 717
 0.61
chr3_16217443_16217716 0.20 GALNT15
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
 1363
 0.53
chr10_6763782_6764322 0.20 PRKCQ
 protein kinase C, theta
 141789
 0.05
chr9_6218213_6218406 0.20 IL33
 interleukin 33
 2500
 0.39
chr13_36047635_36048256 0.20 MAB21L1
 mab-21-like 1 (C. elegans)
 2887
 0.26
chrX_78003533_78003765 0.20 LPAR4
 lysophosphatidic acid receptor 4
 421
 0.91
chr4_186696107_186696537 0.20 SORBS2
 sorbin and SH3 domain containing 2
 108
 0.98
chr7_90012947_90013805 0.20 CLDN12
 claudin 12
 341
 0.9
chr4_18595427_18595619 0.19 LCORL
 ligand dependent nuclear receptor corepressor-like
 572024
 0.0
chr8_93115764_93116215 0.19 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 475
 0.9
chr1_101313202_101313363 0.19 EXTL2
 exostosin-like glycosyltransferase 2
 46938
 0.12
chr2_54195795_54196058 0.18 ACYP2
 acylphosphatase 2, muscle type
 2049
 0.28
chrX_139847648_139847972 0.18 CDR1
 cerebellar degeneration-related protein 1, 34kDa
 18913
 0.23
chr6_53934757_53935103 0.18 MLIP-AS1
 MLIP antisense RNA 1
 9594
 0.22
chr2_152214605_152215087 0.18 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
 740
 0.63
chr8_72273557_72273741 0.18 EYA1
 eyes absent homolog 1 (Drosophila)
 446
 0.9
chr3_120215962_120216316 0.18 FSTL1
 follistatin-like 1
 46039
 0.16
chr9_133712337_133712924 0.18 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 2177
 0.35
chr4_86397582_86397737 0.18 ARHGAP24
 Rho GTPase activating protein 24
 1268
 0.64
chr12_88971091_88971358 0.17 KITLG
 KIT ligand
 3014
 0.3
chr7_30636157_30636308 0.17 ENSG00000196295
 .
 1807
 0.29
chr1_94882933_94883167 0.17 ABCD3
 ATP-binding cassette, sub-family D (ALD), member 3
 883
 0.72
chr18_12076288_12076458 0.17 ANKRD62
 ankyrin repeat domain 62
 17479
 0.16
chr8_107738861_107739281 0.17 OXR1
 oxidation resistance 1
 658
 0.71
chr1_56136277_56136451 0.17 ENSG00000272051
 .
 185719
 0.03
chr6_3749707_3750198 0.17 RP11-420L9.5
1393
 0.41
chr12_89619824_89620001 0.17 ENSG00000238302
 .
 56150
 0.16
chr12_78336681_78336916 0.17 NAV3
 neuron navigator 3
 23258
 0.28
chr9_12776574_12776837 0.17 LURAP1L
 leucine rich adaptor protein 1-like
 1685
 0.38
chr12_117036919_117037510 0.17 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 23558
 0.24
chr6_150176715_150177267 0.17 RP11-350J20.12
3393
 0.15
chr4_102277856_102278206 0.17 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
 8596
 0.2
chr2_175711229_175711408 0.17 CHN1
 chimerin 1
 175
 0.97
chr15_61326560_61326811 0.16 RP11-39M21.1
146763
 0.04
chr1_179279550_179279920 0.16 SOAT1
 sterol O-acyltransferase 1
 16280
 0.19
chr6_135679919_135680436 0.16 AHI1
 Abelson helper integration site 1
 52469
 0.13
chr6_53928343_53928541 0.16 MLIP-AS1
 MLIP antisense RNA 1
 16050
 0.2
chr6_12491048_12491213 0.16 ENSG00000223321
 .
 84117
 0.11
chr11_12699031_12699547 0.16 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 2239
 0.43
chr6_86114788_86115158 0.16 NT5E
 5'-nucleotidase, ecto (CD73)
 44836
 0.19
chr3_127454933_127455119 0.16 MGLL
 monoglyceride lipase
 174
 0.96
chr11_89113858_89114276 0.16 NOX4
 NADPH oxidase 4
 109833
 0.07
chr18_43061735_43061886 0.16 RP11-309E23.2
1373
 0.35
chr4_81195528_81195918 0.16 FGF5
 fibroblast growth factor 5
 7930
 0.26
chr2_163098757_163099006 0.16 FAP
 fibroblast activation protein, alpha
 677
 0.75
chr5_54456050_54456451 0.16 GPX8
 glutathione peroxidase 8 (putative)
 252
 0.86
chr4_41215270_41215769 0.16 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 956
 0.59
chr4_128553582_128553997 0.16 INTU
 inturned planar cell polarity protein
 298
 0.94
chr21_17654570_17655007 0.16 ENSG00000201025
 .
 2301
 0.46
chr10_128110723_128110922 0.16 ADAM12
 ADAM metallopeptidase domain 12
 33798
 0.19
chr5_149534487_149534742 0.15 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 576
 0.7
chr12_106530238_106530817 0.15 NUAK1
 NUAK family, SNF1-like kinase, 1
 3284
 0.3
chr2_166326382_166326565 0.15 CSRNP3
 cysteine-serine-rich nuclear protein 3
 265
 0.96
chr13_45147711_45147927 0.15 TSC22D1
 TSC22 domain family, member 1
 2573
 0.38
chr1_172109829_172110023 0.15 ENSG00000207949
 .
 1879
 0.31
chr8_93074323_93074520 0.15 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 770
 0.78
chr1_172112919_172113144 0.15 ENSG00000208024
 .
 753
 0.46
chr9_18475768_18475931 0.15 ADAMTSL1
 ADAMTS-like 1
 1618
 0.53
chr11_121969171_121969347 0.15 ENSG00000207971
 .
 1293
 0.36
chr6_19691587_19692480 0.15 ENSG00000200957
 .
 49273
 0.18
chr3_150088154_150088521 0.15 TSC22D2
 TSC22 domain family, member 2
 37785
 0.2
chr1_86047684_86048329 0.15 CYR61
 cysteine-rich, angiogenic inducer, 61
 1562
 0.37
chr7_41740779_41741576 0.15 INHBA
 inhibin, beta A
 970
 0.56
chr6_169653019_169653284 0.15 THBS2
 thrombospondin 2
 905
 0.7
chr4_152146952_152147499 0.15 SH3D19
 SH3 domain containing 19
 7
 0.98
chr6_148664293_148664728 0.15 SASH1
 SAM and SH3 domain containing 1
 781
 0.74
chr7_116167346_116167524 0.15 CAV1
 caveolin 1, caveolae protein, 22kDa
 1088
 0.46
chr8_17353947_17354148 0.15 SLC7A2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 550
 0.83
chr5_54456456_54456818 0.15 GPX8
 glutathione peroxidase 8 (putative)
 639
 0.58
chr12_13350846_13351208 0.15 EMP1
 epithelial membrane protein 1
 1307
 0.55
chr10_95241236_95241428 0.15 MYOF
 myoferlin
 619
 0.72
chr12_54017495_54017675 0.15 ATF7
 activating transcription factor 7
 2170
 0.23
chr3_168759646_168760009 0.15 MECOM
 MDS1 and EVI1 complex locus
 85995
 0.11
chr1_95005421_95005705 0.15 F3
 coagulation factor III (thromboplastin, tissue factor)
 1630
 0.52
chr17_1665908_1666244 0.14 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
 47
 0.96
chr2_98765349_98765752 0.14 VWA3B
 von Willebrand factor A domain containing 3B
 61851
 0.13
chr5_121305560_121305763 0.14 SRFBP1
 serum response factor binding protein 1
 8005
 0.28
chr7_94027358_94027511 0.14 COL1A2
 collagen, type I, alpha 2
 3561
 0.34
chr12_960802_961189 0.14 WNK1
 WNK lysine deficient protein kinase 1
 136
 0.97
chr1_61586045_61586196 0.14 RP4-802A10.1
4285
 0.26
chr13_24045503_24045654 0.14 SACS
 spastic ataxia of Charlevoix-Saguenay (sacsin)
 37737
 0.21
chr3_55520495_55520928 0.14 WNT5A
 wingless-type MMTV integration site family, member 5A
 620
 0.62
chr8_55294341_55294557 0.14 ENSG00000244107
 .
 38579
 0.17
chr7_28111372_28111552 0.14 JAZF1
 JAZF zinc finger 1
 159
 0.97
chr11_121970307_121971111 0.14 ENSG00000207971
 .
 157
 0.79
chr15_49715580_49715731 0.14 FGF7
 fibroblast growth factor 7
 198
 0.96
chr5_158176993_158177383 0.14 CTD-2363C16.1
232826
 0.02
chr4_144208077_144208509 0.14 ENSG00000200049
 .
 22326
 0.19
chr2_190043558_190043796 0.14 COL5A2
 collagen, type V, alpha 2
 928
 0.65
chr18_56245541_56245920 0.14 RP11-126O1.2
21428
 0.14
chr7_100770539_100770851 0.14 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 316
 0.81
chr4_119811163_119811314 0.14 SYNPO2
 synaptopodin 2
 1046
 0.64
chr3_100785098_100785499 0.14 ABI3BP
 ABI family, member 3 (NESH) binding protein
 72939
 0.11
chr10_15667073_15667371 0.14 ITGA8
 integrin, alpha 8
 94902
 0.09
chr5_72733592_72733937 0.14 FOXD1
 forkhead box D1
 10588
 0.21
chr5_57753977_57754128 0.14 PLK2
 polo-like kinase 2
 2035
 0.38
chr2_190044119_190044339 0.14 COL5A2
 collagen, type V, alpha 2
 376
 0.9
chr2_238318512_238318719 0.14 COL6A3
 collagen, type VI, alpha 3
 4176
 0.24
chr4_23890359_23890765 0.14 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
 1096
 0.66
chr2_197831667_197831951 0.14 ANKRD44
 ankyrin repeat domain 44
 33417
 0.18
chr15_63673315_63673584 0.14 CA12
 carbonic anhydrase XII
 585
 0.82
chrX_3467246_3467792 0.14 ENSG00000212214
 .
 17227
 0.19
chr5_38555642_38555941 0.14 LIFR
 leukemia inhibitory factor receptor alpha
 947
 0.37
chr4_162267666_162267817 0.14 RP11-234O6.2
32364
 0.26
chr3_15838336_15838568 0.14 ANKRD28
 ankyrin repeat domain 28
 424
 0.86
chr11_69458516_69459047 0.14 CCND1
 cyclin D1
 2807
 0.29
chr8_92612283_92612746 0.14 ENSG00000200151
 .
 5321
 0.33
chr7_18549761_18549974 0.14 HDAC9
 histone deacetylase 9
 931
 0.71
chr18_416158_416713 0.13 RP11-720L2.2
7981
 0.25
chr3_55520023_55520469 0.13 WNT5A
 wingless-type MMTV integration site family, member 5A
 1085
 0.48
chr12_91575190_91575391 0.13 DCN
 decorin
 537
 0.85
chr1_214723918_214724069 0.13 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 573
 0.84
chr4_151500686_151500914 0.13 RP11-1336O20.2
559
 0.76
chr7_41742004_41742175 0.13 INHBA
 inhibin, beta A
 617
 0.72
chr2_164591967_164592245 0.13 FIGN
 fidgetin
 411
 0.92
chr10_33622034_33622426 0.13 NRP1
 neuropilin 1
 1080
 0.63
chr10_35102663_35102949 0.13 PARD3
 par-3 family cell polarity regulator
 1443
 0.4
chr15_37394480_37395011 0.13 MEIS2
 Meis homeobox 2
 1241
 0.49
chr3_66139685_66140118 0.13 SLC25A26
 solute carrier family 25 (S-adenosylmethionine carrier), member 26
 20616
 0.25
chr10_95239483_95239707 0.13 MYOF
 myoferlin
 2356
 0.29
chr15_49718765_49718970 0.13 FGF7
 fibroblast growth factor 7
 3410
 0.29
chr22_45865037_45865472 0.13 RP1-102D24.5
20630
 0.17
chr16_21199797_21200120 0.13 AF001550.7
6210
 0.15
chr19_18497517_18497681 0.13 ENSG00000264175
 .
 227
 0.74
chr4_23890131_23890306 0.13 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
 1440
 0.57
chr19_47735595_47736220 0.13 BBC3
 BCL2 binding component 3
 116
 0.95
chr21_28217168_28217584 0.13 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 352
 0.91
chr5_40552090_40552408 0.13 ENSG00000199552
 .
 102816
 0.07
chr3_190580567_190581193 0.13 GMNC
 geminin coiled-coil domain containing
 476
 0.9
chr11_101983358_101983513 0.13 YAP1
 Yes-associated protein 1
 190
 0.94
chr13_38171648_38172094 0.13 POSTN
 periostin, osteoblast specific factor
 992
 0.71
chr12_69418432_69418757 0.13 CPM
 carboxypeptidase M
 61545
 0.11
chr12_13351879_13352395 0.13 EMP1
 epithelial membrane protein 1
 2417
 0.37
chr3_99356455_99356606 0.13 COL8A1
 collagen, type VIII, alpha 1
 789
 0.74
chr12_104982084_104982267 0.13 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 451
 0.85
chr1_216773992_216774229 0.13 ESRRG
 estrogen-related receptor gamma
 122564
 0.06
chr3_11196334_11196700 0.13 HRH1
 histamine receptor H1
 303
 0.94
chr11_57529774_57530544 0.13 CTNND1
 catenin (cadherin-associated protein), delta 1
 869
 0.5
chr6_56556821_56557065 0.13 DST
 dystonin
 49149
 0.18
chr12_115119174_115119325 0.13 TBX3
 T-box 3
 2146
 0.36
chr4_111557687_111558154 0.13 PITX2
 paired-like homeodomain 2
 256
 0.95
chr2_163099691_163099877 0.13 FAP
 fibroblast activation protein, alpha
 182
 0.96
chr2_67601751_67601914 0.13 ETAA1
 Ewing tumor-associated antigen 1
 22619
 0.29
chr18_52626293_52626952 0.13 CCDC68
 coiled-coil domain containing 68
 117
 0.97
chr10_111765795_111766267 0.13 ADD3
 adducin 3 (gamma)
 469
 0.79
chr1_182931948_182932121 0.13 ENSG00000264768
 .
 3324
 0.2
chr14_52121858_52122101 0.13 FRMD6
 FERM domain containing 6
 3281
 0.25
chr8_27694457_27694746 0.13 PBK
 PDZ binding kinase
 998
 0.51
chr2_235862821_235863118 0.13 SH3BP4
 SH3-domain binding protein 4
 2249
 0.48
chr2_74780571_74780754 0.13 LOXL3
 lysyl oxidase-like 3
 400
 0.5
chr11_95835777_95835928 0.13 MTMR2
 myotubularin related protein 2
 178393
 0.03
chr3_114790362_114790748 0.13 ZBTB20
 zinc finger and BTB domain containing 20
 333
 0.94
chr11_79148844_79149050 0.13 TENM4
 teneurin transmembrane protein 4
 2748
 0.3
chr22_38864455_38864654 0.13 KDELR3
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
 471
 0.74
chr5_124536368_124536614 0.13 ENSG00000222107
 .
 150333
 0.05
chr15_63337269_63337696 0.13 TPM1
 tropomyosin 1 (alpha)
 1507
 0.37
chr6_56557534_56557976 0.13 DST
 dystonin
 49961
 0.18
chr7_23286622_23287130 0.13 GPNMB
 glycoprotein (transmembrane) nmb
 482
 0.83
chr1_170634717_170634868 0.13 PRRX1
 paired related homeobox 1
 1714
 0.5
chr3_124604600_124604823 0.12 ITGB5
 integrin, beta 5
 1433
 0.47
chr5_54457024_54457471 0.12 GPX8
 glutathione peroxidase 8 (putative)
 1249
 0.31
chr7_130595370_130595521 0.12 ENSG00000226380
 .
 33147
 0.2
chr9_13787422_13787665 0.12 NFIB
 nuclear factor I/B
 393248
 0.01
chr18_73688861_73689088 0.12 RP11-94B19.4
 Uncharacterized protein
 282147
 0.01
chr11_133995025_133995278 0.12 NCAPD3
 non-SMC condensin II complex, subunit D3
 43216
 0.13
chr14_27065632_27065895 0.12 NOVA1
 neuro-oncological ventral antigen 1
 482
 0.74
chr7_27218725_27218915 0.12 RP1-170O19.20
 Uncharacterized protein
 812
 0.27
chr3_29325145_29325351 0.12 RBMS3
 RNA binding motif, single stranded interacting protein 3
 2141
 0.37
chr21_17442999_17443232 0.12 ENSG00000252273
 .
 35286
 0.24
chr10_4285552_4285907 0.12 ENSG00000207124
 .
 271415
 0.02
chr7_55088709_55088860 0.12 EGFR
 epidermal growth factor receptor
 1973
 0.48
chr9_22084576_22084735 0.12 CDKN2B-AS1
 CDKN2B antisense RNA 1
 29022
 0.19
chr13_35963159_35963423 0.12 MAB21L1
 mab-21-like 1 (C. elegans)
 87541
 0.09
chr15_56206351_56206878 0.12 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
 1238
 0.55
chr14_73492682_73492833 0.12 ZFYVE1
 zinc finger, FYVE domain containing 1
 1057
 0.51

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0031223 auditory behavior(GO:0031223)
0.1 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.3 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.2 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.1 GO:0090196 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0010667 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0051280 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.0 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0060214 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0002913 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.3 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.0 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0090399 replicative senescence(GO:0090399)
0.0 0.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.5 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME PI 3K CASCADE Genes involved in PI-3K cascade
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling