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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for SOX9

Z-value: 0.55

Motif logo

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Transcription factors associated with SOX9

Gene Symbol Gene ID Gene Info
SOX9
ENSG00000125398.5 SRY-box transcription factor 9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_70117705_70117946SOX96640.821863-0.684.6e-02Click!
chr17_70118144_70118357SOX910890.670792-0.674.7e-02Click!
chr17_70358322_70358473SOX92412360.019037-0.627.3e-02Click!
chr17_70113280_70113463SOX937900.358750-0.617.8e-02Click!
chr17_70269373_70269524SOX91522870.043999-0.618.0e-02Click!

Activity of the SOX9 motif across conditions

Conditions sorted by the z-value of the SOX9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr21_15917471_15917848 0.46 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 1003
 0.63
chr2_65245033_65245279 0.36 AC007386.4
19475
 0.14
chr15_86098904_86099149 0.31 AKAP13
 A kinase (PRKA) anchor protein 13
 349
 0.88
chr15_50411579_50411857 0.30 ATP8B4
 ATPase, class I, type 8B, member 4
 299
 0.92
chr1_212428535_212428756 0.29 PPP2R5A
 protein phosphatase 2, regulatory subunit B', alpha
 30234
 0.16
chr12_10282570_10282865 0.29 CLEC7A
 C-type lectin domain family 7, member A
 35
 0.96
chr13_114823175_114823405 0.27 RASA3
 RAS p21 protein activator 3
 20148
 0.23
chr12_54891563_54891796 0.27 NCKAP1L
 NCK-associated protein 1-like
 184
 0.93
chr11_64215600_64216212 0.26 AP003774.4
 HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
 640
 0.68
chr22_17305454_17306380 0.25 HSFY1P1
 heat shock transcription factor, Y-linked 1 pseudogene 1
 2524
 0.24
chr2_103034578_103034791 0.24 IL18RAP
 interleukin 18 receptor accessory protein
 465
 0.76
chrX_47489873_47490024 0.23 CFP
 complement factor properdin
 244
 0.88
chr21_36881240_36881456 0.23 ENSG00000211590
 .
 211665
 0.02
chr22_50242150_50242826 0.22 ZBED4
 zinc finger, BED-type containing 4
 5002
 0.2
chr12_49616622_49616880 0.22 TUBA1C
 tubulin, alpha 1c
 4958
 0.14
chr8_145086794_145086945 0.22 PARP10
 poly (ADP-ribose) polymerase family, member 10
 71
 0.74
chr10_135091510_135091693 0.21 ADAM8
 ADAM metallopeptidase domain 8
 1229
 0.29
chr10_111783224_111783375 0.21 ADD3
 adducin 3 (gamma)
 15577
 0.2
chr15_94866308_94866459 0.21 MCTP2
 multiple C2 domains, transmembrane 2
 24888
 0.28
chr6_10598498_10598818 0.20 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
 12679
 0.17
chr15_85315766_85316058 0.20 ZNF592
 zinc finger protein 592
 9973
 0.14
chr9_93558631_93558871 0.19 SYK
 spleen tyrosine kinase
 5318
 0.35
chr8_90789610_90789761 0.19 RIPK2
 receptor-interacting serine-threonine kinase 2
 19623
 0.27
chr11_9271619_9271993 0.19 RP11-5L12.1
4750
 0.21
chr14_23218066_23218219 0.19 ENSG00000212302
 .
 7896
 0.12
chr4_139219992_139220143 0.18 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 56564
 0.17
chr12_95043269_95044318 0.18 TMCC3
 transmembrane and coiled-coil domain family 3
 545
 0.85
chr6_114178016_114178613 0.18 MARCKS
 myristoylated alanine-rich protein kinase C substrate
 227
 0.93
chr1_211780463_211780858 0.18 RP11-359E8.5
23593
 0.15
chr5_39177582_39177762 0.18 FYB
 FYN binding protein
 25457
 0.23
chr18_2653530_2653681 0.18 SMCHD1
 structural maintenance of chromosomes flexible hinge domain containing 1
 2132
 0.25
chrX_44203680_44203969 0.18 EFHC2
 EF-hand domain (C-terminal) containing 2
 906
 0.71
chr2_135070643_135070794 0.18 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 58888
 0.15
chr8_131004829_131004980 0.17 ENSG00000253043
 .
 11943
 0.17
chr9_135855020_135855171 0.17 GFI1B
 growth factor independent 1B transcription repressor
 997
 0.42
chr3_186250449_186250600 0.17 CRYGS
 crystallin, gamma S
 11716
 0.17
chr1_161578680_161578831 0.17 FCGR2C
 Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
 13412
 0.11
chr17_29639732_29640055 0.17 EVI2B
 ecotropic viral integration site 2B
 1209
 0.36
chr16_81852082_81852236 0.17 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
 39296
 0.2
chr15_101783225_101783409 0.17 CHSY1
 chondroitin sulfate synthase 1
 8820
 0.18
chr5_55711467_55711618 0.17 ENSG00000265665
 .
 41423
 0.16
chr2_143829142_143829293 0.16 ARHGAP15
 Rho GTPase activating protein 15
 19714
 0.25
chr1_110429914_110430065 0.16 RP11-195M16.1
1103
 0.5
chr4_6940579_6940730 0.16 ENSG00000265953
 .
 14362
 0.15
chr19_36444792_36444943 0.16 LRFN3
 leucine rich repeat and fibronectin type III domain containing 3
 16845
 0.09
chr5_70316349_70316527 0.16 NAIP
 NLR family, apoptosis inhibitory protein
 99
 0.98
chr5_17255187_17255338 0.16 ENSG00000252908
 .
 14542
 0.19
chr5_68902997_68903156 0.16 RP11-848G14.2
11064
 0.18
chr1_153363978_153364129 0.16 S100A8
 S100 calcium binding protein A8
 389
 0.76
chr12_10096266_10096511 0.16 CLEC12A
 C-type lectin domain family 12, member A
 7527
 0.14
chr19_28271110_28271360 0.16 AC005758.1
138616
 0.05
chr12_116510107_116510258 0.16 ENSG00000200665
 .
 10193
 0.25
chr17_10102219_10102533 0.16 GAS7
 growth arrest-specific 7
 508
 0.83
chr5_69758153_69758307 0.16 RP11-497H16.7
11045
 0.27
chr12_110517460_110517751 0.16 C12orf76
 chromosome 12 open reading frame 76
 6114
 0.22
chr13_41752294_41752445 0.16 ENSG00000238651
 .
 1854
 0.3
chr8_61821706_61823076 0.16 RP11-33I11.2
100226
 0.08
chr21_45509829_45509980 0.16 PWP2
 PWP2 periodic tryptophan protein homolog (yeast)
 17267
 0.16
chr17_57789761_57790061 0.15 VMP1
 vacuole membrane protein 1
 4828
 0.18
chr14_38548074_38548225 0.15 CTD-2058B24.2
12214
 0.26
chr6_109699129_109699388 0.15 CD164
 CD164 molecule, sialomucin
 3645
 0.18
chr7_134846065_134846216 0.15 RP11-134L10.1
7015
 0.14
chr6_6687519_6687926 0.15 LY86-AS1
 LY86 antisense RNA 1
 64718
 0.14
chr12_10019991_10020525 0.15 RP11-290C10.1
632
 0.61
chr19_54345711_54345913 0.15 NLRP12
 NLR family, pyrin domain containing 12
 18164
 0.05
chr13_49478658_49478809 0.15 ENSG00000265585
 .
 25615
 0.21
chr1_192905339_192905490 0.15 ENSG00000223075
 .
 60299
 0.12
chr4_141015619_141015856 0.15 RP11-392B6.1
33432
 0.2
chr10_131555449_131556065 0.15 RP11-109A6.2
55936
 0.14
chr7_33089731_33090334 0.15 ENSG00000241420
 .
 4330
 0.18
chr1_160673796_160673952 0.14 CD48
 CD48 molecule
 7719
 0.16
chr1_235115156_235115307 0.14 ENSG00000239690
 .
 75298
 0.1
chr2_121354385_121354536 0.14 ENSG00000201006
 .
 54389
 0.16
chr7_2570576_2570806 0.14 ENSG00000264357
 .
 3983
 0.17
chr1_221204797_221204948 0.14 HLX
 H2.0-like homeobox
 150288
 0.04
chr11_61738714_61739353 0.14 AP003733.1
 Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
 3580
 0.16
chr2_135051726_135051877 0.14 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 39971
 0.19
chrX_20132855_20133006 0.14 MAP7D2
 MAP7 domain containing 2
 1820
 0.28
chr6_64062151_64062302 0.14 LGSN
 lengsin, lens protein with glutamine synthetase domain
 32344
 0.24
chr6_24932242_24932425 0.14 FAM65B
 family with sequence similarity 65, member B
 3855
 0.28
chr5_14560333_14560610 0.14 FAM105A
 family with sequence similarity 105, member A
 21413
 0.23
chr20_44689695_44689846 0.14 NCOA5
 nuclear receptor coactivator 5
 28821
 0.11
chr3_13002263_13002414 0.14 IQSEC1
 IQ motif and Sec7 domain 1
 6830
 0.26
chr7_112062054_112062259 0.14 IFRD1
 interferon-related developmental regulator 1
 867
 0.64
chr4_55534639_55534790 0.13 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 10629
 0.31
chr4_141174038_141174780 0.13 SCOC
 short coiled-coil protein
 4031
 0.26
chr9_84494361_84494512 0.13 ENSG00000252167
 .
 5975
 0.17
chr3_63793614_63793765 0.13 AC136289.1
2920
 0.24
chrX_135961684_135962842 0.13 RBMX
 RNA binding motif protein, X-linked
 621
 0.53
chr20_39657787_39658990 0.13 TOP1
 topoisomerase (DNA) I
 930
 0.61
chr1_16160235_16160851 0.13 RP11-169K16.9
1812
 0.28
chr17_73774322_73775453 0.13 H3F3B
 H3 histone, family 3B (H3.3B)
 480
 0.64
chr5_134761710_134761905 0.13 C5orf20
 chromosome 5 open reading frame 20
 21231
 0.12
chr7_140615501_140615652 0.13 BRAF
 v-raf murine sarcoma viral oncogene homolog B
 8988
 0.22
chr10_3527831_3528010 0.13 RP11-184A2.3
265339
 0.02
chr1_3527588_3528047 0.13 MEGF6
 multiple EGF-like-domains 6
 242
 0.89
chr1_204940483_204940634 0.13 NFASC
 neurofascin
 10426
 0.21
chr6_105153386_105153605 0.13 ENSG00000252944
 .
 61202
 0.13
chr9_297994_298145 0.13 DOCK8
 dedicator of cytokinesis 8
 24999
 0.18
chr15_93426669_93427240 0.12 CHD2
 chromodomain helicase DNA binding protein 2
 428
 0.83
chr20_48887078_48887229 0.12 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
 79777
 0.09
chr7_105998110_105998261 0.12 NAMPT
 nicotinamide phosphoribosyltransferase
 71413
 0.11
chr17_66433856_66434617 0.12 WIPI1
 WD repeat domain, phosphoinositide interacting 1
 4524
 0.23
chr2_68953487_68953638 0.12 ARHGAP25
 Rho GTPase activating protein 25
 8351
 0.26
chrX_135738768_135738919 0.12 CD40LG
 CD40 ligand
 8457
 0.18
chr12_93163278_93163429 0.12 PLEKHG7
 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
 33042
 0.18
chr1_161600101_161600252 0.12 FCGR3B
 Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
 646
 0.42
chr3_46970853_46971178 0.12 PTH1R
 parathyroid hormone 1 receptor
 26926
 0.13
chr14_24641513_24641917 0.12 REC8
 REC8 meiotic recombination protein
 105
 0.89
chr11_65378670_65378821 0.12 MAP3K11
 mitogen-activated protein kinase kinase kinase 11
 27
 0.93
chr12_57870819_57871184 0.12 ARHGAP9
 Rho GTPase activating protein 9
 566
 0.53
chr22_36632572_36632723 0.12 APOL2
 apolipoprotein L, 2
 2626
 0.25
chr12_121676925_121677077 0.12 CAMKK2
 calcium/calmodulin-dependent protein kinase kinase 2, beta
 21344
 0.16
chr3_184395596_184395747 0.12 MAGEF1
 melanoma antigen family F, 1
 34165
 0.19
chr3_36937026_36937306 0.12 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
 36792
 0.17
chr2_169940004_169940155 0.12 DHRS9
 dehydrogenase/reductase (SDR family) member 9
 2462
 0.31
chr13_31943501_31943652 0.12 B3GALTL
 beta 1,3-galactosyltransferase-like
 169503
 0.04
chr4_153600093_153601094 0.12 TMEM154
 transmembrane protein 154
 571
 0.78
chr7_104584020_104584171 0.12 ENSG00000251911
 .
 27639
 0.16
chr1_150550029_150550609 0.11 MCL1
 myeloid cell leukemia sequence 1 (BCL2-related)
 1687
 0.18
chr3_152939222_152939486 0.11 ENSG00000265813
 .
 21548
 0.22
chr18_9701912_9702261 0.11 RAB31
 RAB31, member RAS oncogene family
 6076
 0.24
chr18_2960483_2961188 0.11 RP11-737O24.1
6181
 0.16
chr5_77807061_77807212 0.11 LHFPL2
 lipoma HMGIC fusion partner-like 2
 37838
 0.21
chr12_80321477_80321628 0.11 PPP1R12A
 protein phosphatase 1, regulatory subunit 12A
 6943
 0.2
chr13_77324135_77324286 0.11 KCTD12
 potassium channel tetramerization domain containing 12
 136315
 0.05
chr5_37317955_37318106 0.11 ENSG00000251880
 .
 9207
 0.22
chr6_39282333_39282484 0.11 KCNK17
 potassium channel, subfamily K, member 17
 79
 0.98
chr17_27256722_27256873 0.11 PHF12
 PHD finger protein 12
 1489
 0.19
chr6_89754695_89754846 0.11 ENSG00000223001
 .
 18639
 0.15
chr11_82608630_82608781 0.11 C11orf82
 chromosome 11 open reading frame 82
 2312
 0.28
chr11_48088687_48088966 0.11 ENSG00000263693
 .
 29508
 0.17
chr7_5710794_5710945 0.11 RNF216-IT1
 RNF216 intronic transcript 1 (non-protein coding)
 9223
 0.21
chr4_88896230_88897032 0.11 SPP1
 secreted phosphoprotein 1
 188
 0.95
chr2_223536011_223536232 0.11 MOGAT1
 monoacylglycerol O-acyltransferase 1
 384
 0.86
chr10_81947502_81948014 0.11 ANXA11
 annexin A11
 14981
 0.2
chr19_16482667_16482930 0.11 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 10034
 0.15
chr18_379614_379765 0.11 RP11-720L2.2
44727
 0.16
chr15_99074007_99074158 0.11 FAM169B
 family with sequence similarity 169, member B
 16471
 0.27
chr2_192604587_192604738 0.11 AC098872.3
53489
 0.14
chr5_119593776_119593927 0.11 ENSG00000251975
 .
 79497
 0.12
chr14_64806720_64806871 0.11 RP11-544I20.2
1478
 0.34
chr16_27301591_27301742 0.11 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 21551
 0.15
chr12_805861_806012 0.11 NINJ2
 ninjurin 2
 32991
 0.15
chr9_7653385_7653536 0.11 TMEM261
 transmembrane protein 261
 146607
 0.05
chr5_126147731_126147991 0.11 LMNB1
 lamin B1
 34980
 0.19
chr7_143080537_143080688 0.10 ZYX
 zyxin
 519
 0.65
chr1_61543284_61543773 0.10 NFIA
 nuclear factor I/A
 582
 0.78
chr2_201987013_201987300 0.10 CFLAR
 CASP8 and FADD-like apoptosis regulator
 44
 0.96
chr12_110562218_110563151 0.10 IFT81
 intraflagellar transport 81 homolog (Chlamydomonas)
 487
 0.84
chr21_34602307_34603720 0.10 IFNAR2
 interferon (alpha, beta and omega) receptor 2
 299
 0.87
chr20_8583214_8583783 0.10 ENSG00000221201
 .
 6329
 0.25
chr1_183556161_183556312 0.10 NCF2
 neutrophil cytosolic factor 2
 3480
 0.25
chr15_92012895_92013046 0.10 SV2B
 synaptic vesicle glycoprotein 2B
 243870
 0.02
chr8_70650371_70650522 0.10 RP11-102F4.2
24821
 0.19
chr7_23246593_23246744 0.10 NUPL2
 nucleoporin like 2
 24985
 0.16
chr6_42537305_42537764 0.10 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
 5734
 0.24
chr17_68678856_68679007 0.10 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 513255
 0.0
chr8_90995843_90996298 0.10 NBN
 nibrin
 395
 0.87
chr4_6909699_6909850 0.10 TBC1D14
 TBC1 domain family, member 14
 1195
 0.49
chr20_45028360_45028511 0.10 ELMO2
 engulfment and cell motility 2
 5314
 0.24
chr11_94335838_94335989 0.10 PIWIL4
 piwi-like RNA-mediated gene silencing 4
 15042
 0.2
chr8_27141347_27141498 0.10 TRIM35
 tripartite motif containing 35
 10230
 0.19
chr13_48809687_48810120 0.10 ITM2B
 integral membrane protein 2B
 2564
 0.37
chr2_33355355_33355506 0.10 LTBP1
 latent transforming growth factor beta binding protein 1
 4043
 0.34
chr11_93451363_93451537 0.10 ENSG00000199875
 .
 1319
 0.18
chr15_92404035_92404308 0.10 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 6820
 0.27
chr7_155484798_155484949 0.10 RBM33
 RNA binding motif protein 33
 8712
 0.25
chr6_138176930_138177081 0.10 RP11-356I2.4
2180
 0.35
chr10_102106243_102106464 0.10 RP11-34D15.2
206
 0.76
chr1_164489142_164489293 0.10 PBX1
 pre-B-cell leukemia homeobox 1
 39220
 0.2
chr1_29241076_29241272 0.10 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
 83
 0.97
chr2_218990770_218991030 0.10 CXCR2
 chemokine (C-X-C motif) receptor 2
 158
 0.95
chr2_48338474_48339359 0.10 ENSG00000201010
 .
 105798
 0.07
chr1_21503574_21503811 0.10 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
 315
 0.69
chr4_79583127_79583675 0.10 ENSG00000238816
 .
 22147
 0.19
chr1_207495975_207496182 0.10 CD55
 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
 942
 0.68
chr12_40547331_40547482 0.10 LRRK2
 leucine-rich repeat kinase 2
 43140
 0.16
chr19_23427286_23427437 0.09 ZNF724P
 zinc finger protein 724, pseudogene
 5801
 0.26
chr18_72163609_72164283 0.09 CNDP2
 CNDP dipeptidase 2 (metallopeptidase M20 family)
 328
 0.9
chr21_37557715_37557866 0.09 DOPEY2
 dopey family member 2
 20957
 0.12
chr1_200335563_200335714 0.09 ZNF281
 zinc finger protein 281
 43482
 0.2
chr5_98265881_98266063 0.09 CHD1
 chromodomain helicase DNA binding protein 1
 3732
 0.25
chr5_1501228_1501379 0.09 LPCAT1
 lysophosphatidylcholine acyltransferase 1
 22789
 0.19
chrX_119737965_119739054 0.09 MCTS1
 malignant T cell amplified sequence 1
 333
 0.88
chr14_92942291_92942442 0.09 SLC24A4
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
 36658
 0.18
chr3_119814638_119815091 0.09 GSK3B
 glycogen synthase kinase 3 beta
 1600
 0.39
chr4_10642308_10642459 0.09 CLNK
 cytokine-dependent hematopoietic cell linker
 15802
 0.3
chr2_70474548_70475674 0.09 TIA1
 TIA1 cytotoxic granule-associated RNA binding protein
 475
 0.73
chr10_90593785_90593936 0.09 ANKRD22
 ankyrin repeat domain 22
 17715
 0.16
chr2_143909648_143909799 0.09 RP11-190J23.1
20018
 0.22
chr12_32740907_32741058 0.09 FGD4
 FYVE, RhoGEF and PH domain containing 4
 10478
 0.26
chr9_108104857_108105008 0.09 SLC44A1
 solute carrier family 44 (choline transporter), member 1
 12825
 0.28
chr16_17547681_17547832 0.09 XYLT1
 xylosyltransferase I
 16982
 0.31
chr16_30103433_30103902 0.09 TBX6
 T-box 6
 459
 0.59
chr8_38325453_38326142 0.09 FGFR1
 fibroblast growth factor receptor 1
 337
 0.87
chr10_49922246_49922397 0.09 WDFY4
 WDFY family member 4
 4570
 0.28
chr1_84610970_84611403 0.09 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
 1232
 0.6
chr6_53130180_53130331 0.09 ENSG00000264056
 .
 11536
 0.19
chr9_117721707_117721858 0.09 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 29085
 0.23

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.2 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:2000380 regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0000239 pachytene(GO:0000239)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:1904019 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.0 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0008091 spectrin(GO:0008091)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001846 opsonin binding(GO:0001846)
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.3 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK