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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SP4_PML

Z-value: 7.28

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Transcription factors associated with SP4_PML

Gene Symbol	Gene ID	Gene Info
SP4 Ensembl NCBI GeneCards UniProt	ENSG00000105866.9	SP4
PML Ensembl NCBI GeneCards UniProt	ENSG00000140464.15	PML

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
PML	chr15_74333289_74333462	16154	0.138021	0.78	1.4e-02	Click!
PML	chr15_74290143_74290294	3074	0.196867	0.77	1.5e-02	Click!
PML	chr15_74304230_74304381	10948	0.152119	0.63	6.8e-02	Click!
PML	chr15_74333685_74333836	16539	0.137216	0.61	7.9e-02	Click!
PML	chr15_74303888_74304052	11283	0.151450	0.53	1.4e-01	Click!
SP4	chr7_21472009_21472160	4423	0.218089	-0.77	1.5e-02	Click!
SP4	chr7_21471488_21471682	3924	0.226600	-0.75	1.9e-02	Click!
SP4	chr7_21470822_21470973	3236	0.244610	-0.68	4.5e-02	Click!
SP4	chr7_21470215_21470407	2650	0.270533	-0.67	4.8e-02	Click!
SP4	chr7_21471147_21471369	3597	0.233998	-0.62	7.3e-02	Click!

Activity of the SP4_PML motif across conditions

Conditions sorted by the z-value of the SP4_PML motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_14924992_14926197	20.80	KAZN	kazrin, periplakin interacting protein	381	0.93
chr10_79396627_79397649	16.61	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	67	0.98
chr6_72129322_72130506	12.68	ENSG00000207827	.	16590	0.22
chr1_180881914_180882730	12.53	KIAA1614	KIAA1614	3	0.98
chr22_43115644_43116713	12.47	A4GALT	alpha 1,4-galactosyltransferase	24539	0.15
chr2_242497891_242499073	12.28	BOK-AS1	BOK antisense RNA 1	90	0.79
chr7_45002030_45002849	10.14	RP4-647J21.1		1931	0.25
chr17_37856067_37857084	10.07	ERBB2	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2	242	0.86
chr2_160918347_160919586	9.72	PLA2R1	phospholipase A2 receptor 1, 180kDa	155	0.98
chr5_63461313_63462499	9.72	RNF180	ring finger protein 180	83	0.99
chr7_95401616_95402462	9.56	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	123	0.98
chr17_59476045_59476898	9.52	RP11-332H18.4		260	0.74
chr1_110693132_110693795	9.41	SLC6A17	solute carrier family 6 (neutral amino acid transporter), member 17	355	0.81
chrX_132548696_132549413	9.28	GPC4	glypican 4	464	0.88
chr15_48937037_48938293	9.05	FBN1	fibrillin 1	253	0.95
chr16_85203170_85204140	8.81	CTC-786C10.1		1227	0.55
chr2_54086905_54087527	8.80	GPR75-ASB3	GPR75-ASB3 readthrough	46	0.37
chr2_127976513_127977351	8.75	CYP27C1	cytochrome P450, family 27, subfamily C, polypeptide 1	722	0.74
chr1_65991038_65991651	8.68	RP4-630A11.3		39255	0.14
chr15_73976688_73977423	8.65	CD276	CD276 molecule	17	0.98
chr13_27131903_27132772	8.53	WASF3	WAS protein family, member 3	450	0.89
chr2_167232459_167233133	8.48	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit	293	0.93
chrX_110038687_110039773	8.33	CHRDL1	chordin-like 1	56	0.99
chr8_69242814_69243988	8.28	C8orf34	chromosome 8 open reading frame 34	56	0.82
chr11_70244216_70245100	8.24	CTTN	cortactin	11	0.53
chr9_71939475_71940274	8.17	FAM189A2	family with sequence similarity 189, member A2	386	0.91
chr5_78985270_78986298	8.11	CMYA5	cardiomyopathy associated 5	84	0.98
chr9_113341179_113342041	8.08	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	213	0.96
chr20_49347136_49348386	8.07	PARD6B	par-6 family cell polarity regulator beta	320	0.89
chr9_130159461_130160475	7.98	SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8	305	0.87
chr22_41633466_41634617	7.92	CHADL	chondroadherin-like	1584	0.26
chr16_75284494_75285397	7.83	BCAR1	breast cancer anti-estrogen resistance 1	100	0.96
chr17_34611752_34612896	7.83	CCL3L1	chemokine (C-C motif) ligand 3-like 1	13395	0.14
chr11_57365224_57366004	7.80	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	338	0.8
chr5_1110808_1112337	7.79	SLC12A7	solute carrier family 12 (potassium/chloride transporter), member 7	578	0.75
chr9_140500205_140501463	7.76	ARRDC1	arrestin domain containing 1	679	0.56
chr1_112532383_112532987	7.76	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	908	0.69
chr2_149894818_149895436	7.71	LYPD6B	LY6/PLAUR domain containing 6B	105	0.98
chr9_132382165_132382732	7.64	C9orf50	chromosome 9 open reading frame 50	607	0.62
chr17_76164337_76165654	7.61	SYNGR2	synaptogyrin 2	244	0.87
chr22_19165246_19166141	7.58	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	341	0.82
chr12_7037386_7038830	7.45	ATN1	atrophin 1	632	0.41
chr9_127539201_127540134	7.44	OLFML2A	olfactomedin-like 2A	117	0.95
chr4_150999769_151000790	7.43	DCLK2	doublecortin-like kinase 2	99	0.98
chr7_108095607_108096848	7.35	NRCAM	neuronal cell adhesion molecule	538	0.84
chr1_178063035_178063602	7.31	RASAL2	RAS protein activator like 2	42	0.99
chr11_131780761_131781452	7.28	NTM	neurotrimin	209	0.95
chr12_3308931_3310293	7.27	TSPAN9	tetraspanin 9	729	0.75
chr17_20491916_20492779	7.23	CDRT15L2	CMT1A duplicated region transcript 15-like 2	9310	0.21
chr9_23821130_23821679	7.17	ELAVL2	ELAV like neuron-specific RNA binding protein 2	74	0.99
chr16_2521208_2521831	7.15	NTN3	netrin 3	19	0.93
chr6_54711000_54712080	7.14	FAM83B	family with sequence similarity 83, member B	29	0.98
chr3_126702505_126703684	7.12	PLXNA1	plexin A1	4343	0.34
chr20_4229911_4230312	7.09	ADRA1D	adrenoceptor alpha 1D	390	0.89
chr3_192126971_192127690	7.06	FGF12	fibroblast growth factor 12	492	0.87
chr5_174178214_174178699	7.05	ENSG00000266890	.	281	0.94
chr9_35489468_35490886	7.02	RUSC2	RUN and SH3 domain containing 2	53	0.97
chr7_29846053_29846716	7.00	WIPF3	WAS/WASL interacting protein family, member 3	282	0.94
chrX_83442690_83443328	6.97	RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	76	0.98
chr6_88875424_88876640	6.95	CNR1	cannabinoid receptor 1 (brain)	46	0.99
chr1_231297648_231298418	6.94	TRIM67	tripartite motif containing 67	175	0.95
chr2_239072349_239072829	6.89	FAM132B	family with sequence similarity 132, member B	385	0.8
chr18_25757173_25757741	6.86	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	47	0.99
chr10_21462508_21463481	6.86	NEBL-AS1	NEBL antisense RNA 1	51	0.59
chr10_18429523_18430148	6.86	CACNB2	calcium channel, voltage-dependent, beta 2 subunit	52	0.99
chr14_38063567_38064244	6.82	FOXA1	forkhead box A1	334	0.84
chr2_113956230_113956830	6.80	PSD4	pleckstrin and Sec7 domain containing 4	2673	0.2
chr18_6729547_6730123	6.76	ARHGAP28	Rho GTPase activating protein 28	14	0.5
chr4_75718841_75720131	6.75	BTC	betacellulin	410	0.91
chr11_27740485_27740934	6.74	BDNF	brain-derived neurotrophic factor	585	0.82
chr2_243030793_243031816	6.72	AC093642.5		460	0.62
chr2_71127433_71128165	6.70	VAX2	ventral anterior homeobox 2	79	0.96
chr2_79739509_79740065	6.63	CTNNA2	catenin (cadherin-associated protein), alpha 2	339	0.91
chr7_100464814_100466140	6.63	TRIP6	thyroid hormone receptor interactor 6	717	0.47
chr9_17578628_17579355	6.61	SH3GL2	SH3-domain GRB2-like 2	130	0.98
chr11_111169649_111170452	6.60	COLCA2	colorectal cancer associated 2	74	0.88
chr10_79397825_79398297	6.55	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	66	0.98
chr17_7284064_7284762	6.54	TNK1	tyrosine kinase, non-receptor, 1	48	0.92
chr15_51633704_51634417	6.52	GLDN	gliomedin	234	0.91
chr14_69726344_69726819	6.52	GALNT16	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16	100	0.98
chr5_121647834_121648295	6.49	SNCAIP	synuclein, alpha interacting protein	132	0.9
chr7_89841111_89841428	6.49	STEAP2	STEAP family member 2, metalloreductase	24	0.82
chr19_55684291_55685412	6.47	SYT5	synaptotagmin V	1083	0.28
chr1_934275_935357	6.43	HES4	hes family bHLH transcription factor 4	545	0.57
chr6_5084934_5086227	6.41	PPP1R3G	protein phosphatase 1, regulatory subunit 3G	140	0.97
chr10_128594353_128594780	6.41	DOCK1	dedicator of cytokinesis 1	588	0.8
chr5_129240122_129240866	6.40	CHSY3	chondroitin sulfate synthase 3	329	0.79
chr15_47476270_47477144	6.37	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	409	0.87
chr11_503866_504897	6.36	RNH1	ribonuclease/angiogenin inhibitor 1	171	0.89
chr12_80083529_80084306	6.35	PAWR	PRKC, apoptosis, WT1, regulator	57	0.98
chr19_6740138_6741070	6.32	TRIP10	thyroid hormone receptor interactor 10	325	0.81
chr12_106532817_106533194	6.32	NUAK1	NUAK family, SNF1-like kinase, 1	806	0.7
chr2_218843405_218844030	6.30	TNS1	tensin 1	60	0.79
chr10_118764443_118765166	6.26	KIAA1598	KIAA1598	72	0.98
chrX_102318388_102319159	6.19	BEX1	brain expressed, X-linked 1	395	0.83
chr18_52626293_52626952	6.17	CCDC68	coiled-coil domain containing 68	117	0.97
chr2_236401822_236402641	6.16	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	502	0.83
chr14_70346080_70346697	6.16	SMOC1	SPARC related modular calcium binding 1	245	0.95
chr19_34972837_34973110	6.14	WTIP	Wilms tumor 1 interacting protein	430	0.8
chr5_31193803_31195028	6.11	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	558	0.85
chr19_41073613_41074217	6.11	SHKBP1	SH3KBP1 binding protein 1	8842	0.14
chr1_241520119_241520816	6.11	RGS7	regulator of G-protein signaling 7	63	0.99
chr11_110582275_110583137	6.11	ARHGAP20	Rho GTPase activating protein 20	67	0.99
chr22_50745196_50745796	6.09	PLXNB2	plexin B2	521	0.61
chr19_14315927_14317134	6.08	LPHN1	latrophilin 1	451	0.77
chr3_173114984_173115853	6.06	NLGN1	neuroligin 1	152	0.98
chr12_112818867_112820166	6.02	HECTD4	HECT domain containing E3 ubiquitin protein ligase 4	380	0.87
chr20_23617810_23618640	6.01	CST3	cystatin C	357	0.87
chr15_83875578_83876391	5.98	HDGFRP3	Hepatoma-derived growth factor-related protein 3	786	0.64
chr3_33318777_33319866	5.96	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr17_29036450_29037561	5.96	ENSG00000241631	.	7212	0.17
chr7_150779695_150780926	5.96	TMUB1	transmembrane and ubiquitin-like domain containing 1	9	0.94
chr2_159825200_159826543	5.95	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	688	0.73
chr6_19838575_19839711	5.92	RP1-167F1.2		168	0.95
chr22_37956672_37957106	5.91	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	402	0.77
chr1_15480157_15480820	5.87	TMEM51	transmembrane protein 51	203	0.95
chrX_12156590_12157176	5.84	FRMPD4	FERM and PDZ domain containing 4	298	0.9
chr12_45444664_45445224	5.83	DBX2	developing brain homeobox 2	62	0.76
chr5_54179266_54180220	5.81	ENSG00000221073	.	30967	0.19
chr17_77019963_77021139	5.78	C1QTNF1	C1q and tumor necrosis factor related protein 1	208	0.91
chr2_191044944_191045899	5.77	C2orf88	chromosome 2 open reading frame 88	168	0.96
chr6_166721057_166722024	5.77	PRR18	proline rich 18	331	0.9
chr12_71003154_71004126	5.75	PTPRB	protein tyrosine phosphatase, receptor type, B	16	0.99
chr9_110250307_110251795	5.75	KLF4	Kruppel-like factor 4 (gut)	360	0.89
chr9_113800702_113801367	5.74	LPAR1	lysophosphatidic acid receptor 1	53	0.98
chr19_1566819_1567637	5.69	MEX3D	mex-3 RNA binding family member D	301	0.76
chr12_29936821_29937292	5.68	TMTC1	transmembrane and tetratricopeptide repeat containing 1	226	0.96
chr6_159239962_159240825	5.67	EZR	ezrin	51	0.96
chr6_118228401_118229053	5.66	SLC35F1	solute carrier family 35, member F1	38	0.99
chr4_55096373_55096991	5.66	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	193	0.97
chr16_55542879_55544136	5.65	LPCAT2	lysophosphatidylcholine acyltransferase 2	597	0.77
chr16_691284_692401	5.65	FAM195A	family with sequence similarity 195, member A	29	0.92
chr19_13906290_13907522	5.64	ZSWIM4	zinc finger, SWIM-type containing 4	632	0.39
chr4_157997366_157997978	5.63	GLRB	glycine receptor, beta	117	0.97
chr9_86152792_86153773	5.63	FRMD3	FERM domain containing 3	71	0.98
chr6_147829082_147829740	5.62	SAMD5	sterile alpha motif domain containing 5	652	0.84
chr5_38846105_38846894	5.62	OSMR	oncostatin M receptor	398	0.91
chr16_14396121_14396821	5.62	ENSG00000207639	.	1353	0.42
chr13_93879365_93880233	5.61	GPC6	glypican 6	704	0.82
chr8_15094580_15095009	5.58	SGCZ	sarcoglycan, zeta	1054	0.7
chr17_21279729_21280949	5.57	KCNJ12	potassium inwardly-rectifying channel, subfamily J, member 12	830	0.69
chr6_117086060_117086951	5.57	FAM162B	family with sequence similarity 162, member B	381	0.87
chr8_15397591_15398115	5.56	TUSC3	tumor suppressor candidate 3	61	0.98
chr11_120195755_120196855	5.55	TMEM136	transmembrane protein 136	289	0.9
chr16_2517636_2518674	5.55	RP11-715J22.2		59	0.92
chr10_101088892_101089952	5.52	CNNM1	cyclin M1	266	0.95
chr1_220701624_220702485	5.51	MARK1	MAP/microtubule affinity-regulating kinase 1	155	0.97
chr18_11149170_11149978	5.51	PIEZO2	piezo-type mechanosensitive ion channel component 2	987	0.72
chr1_33207592_33208218	5.51	KIAA1522	KIAA1522	419	0.8
chr4_169753076_169754370	5.50	RP11-635L1.3		365	0.61
chr15_56034170_56035376	5.47	PRTG	protogenin	41	0.98
chr6_19838100_19838453	5.46	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	659	0.6
chr6_78172796_78173983	5.46	HTR1B	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	101	0.99
chr9_21974540_21975658	5.45	CDKN2A	cyclin-dependent kinase inhibitor 2A	2	0.97
chr16_85269227_85269622	5.44	CTC-786C10.1		64542	0.11
chr19_41725215_41725482	5.43	AXL	AXL receptor tyrosine kinase	208	0.89
chr9_103235708_103236480	5.42	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1	699	0.7
chr6_84139999_84140706	5.42	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	412	0.89
chr21_46825103_46825740	5.41	COL18A1	collagen, type XVIII, alpha 1	369	0.83
chr1_205648469_205649627	5.40	SLC45A3	solute carrier family 45, member 3	539	0.74
chr22_25348691_25349626	5.40	KIAA1671	KIAA1671	461	0.83
chr20_9048816_9049419	5.39	PLCB4	phospholipase C, beta 4	293	0.9
chr15_65066905_65067558	5.33	RBPMS2	RNA binding protein with multiple splicing 2	555	0.69
chr20_55204347_55205219	5.32	TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	425	0.81
chr11_94473290_94474384	5.30	RP11-867G2.8		316	0.92
chr3_24562978_24563646	5.28	ENSG00000265028	.	386	0.87
chr2_112897330_112897707	5.28	FBLN7	fibulin 7	1358	0.52
chr21_46825742_46826418	5.28	COL18A1	collagen, type XVIII, alpha 1	1028	0.47
chr21_42539308_42539931	5.25	BACE2	beta-site APP-cleaving enzyme 2	109	0.53
chr4_146403033_146403938	5.24	SMAD1	SMAD family member 1	153	0.96
chr9_1051774_1052480	5.21	DMRT2	doublesex and mab-3 related transcription factor 2	513	0.84
chr22_45898941_45899504	5.21	FBLN1	fibulin 1	296	0.92
chrX_138774003_138774873	5.21	MCF2	MCF.2 cell line derived transforming sequence	123	0.97
chr21_38071900_38072434	5.21	SIM2	single-minded family bHLH transcription factor 2	176	0.94
chr6_142622323_142623463	5.20	GPR126	G protein-coupled receptor 126	98	0.98
chr22_29702254_29703430	5.20	GAS2L1	growth arrest-specific 2 like 1	171	0.91
chr16_1664599_1665551	5.19	CRAMP1L	Crm, cramped-like (Drosophila)	434	0.69
chr8_49782515_49783288	5.19	SNAI2	snail family zinc finger 2	51087	0.18
chr7_37960238_37961117	5.18	EPDR1	ependymin related 1	245	0.94
chr2_176994908_176995460	5.18	HOXD8	homeobox D8	99	0.91
chr16_54319557_54319894	5.17	IRX3	iroquois homeobox 3	42	0.98
chr6_46458824_46459774	5.16	RCAN2	regulator of calcineurin 2	200	0.78
chr8_494526_494820	5.16	TDRP	testis development related protein	164	0.97
chr7_55087572_55088165	5.15	EGFR	epidermal growth factor receptor	1057	0.68
chr17_79373625_79374766	5.15	ENSG00000266392	.	383	0.6
chr19_33685813_33686340	5.15	LRP3	low density lipoprotein receptor-related protein 3	586	0.65
chr7_1709889_1710442	5.14	ELFN1	extracellular leucine-rich repeat and fibronectin type III domain containing 1	17590	0.18
chr19_1315736_1316102	5.14	EFNA2	ephrin-A2	29766	0.07
chr16_67282110_67283381	5.14	SLC9A5	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5	108	0.89
chr9_34651822_34652525	5.13	IL11RA	interleukin 11 receptor, alpha	16	0.94
chr5_83017716_83018280	5.12	HAPLN1	hyaluronan and proteoglycan link protein 1	566	0.78
chr2_29338259_29338523	5.09	CLIP4	CAP-GLY domain containing linker protein family, member 4	99	0.96
chr19_4064037_4064881	5.09	ZBTB7A	zinc finger and BTB domain containing 7A	1271	0.28
chr18_35146776_35147412	5.08	CELF4	CUGBP, Elav-like family member 4	1094	0.67
chr10_88159807_88161210	5.08	GRID1	glutamate receptor, ionotropic, delta 1	34273	0.17
chr2_11622794_11623343	5.08	E2F6	E2F transcription factor 6	16793	0.13
chr20_6032553_6033205	5.07	LRRN4	leucine rich repeat neuronal 4	1816	0.35
chr5_131562588_131563831	5.07	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	138	0.96
chrX_9754461_9754895	5.06	SHROOM2	shroom family member 2	182	0.69
chr3_96531977_96533205	5.04	EPHA6	EPH receptor A6	834	0.76

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SP4_PML

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.6	25.8	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
6.6	19.8	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
6.6	13.2	GO:0060677	ureteric bud elongation(GO:0060677)
5.9	17.6	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
5.5	16.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
5.4	16.2	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
5.2	15.5	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
4.8	14.5	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
4.5	13.5	GO:0021508	floor plate formation(GO:0021508)
4.5	4.5	GO:0060594	mammary gland specification(GO:0060594)
4.4	13.2	GO:0016080	synaptic vesicle targeting(GO:0016080)
4.3	17.4	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
4.3	8.6	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
4.3	17.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
4.2	12.5	GO:0051451	myoblast migration(GO:0051451)
4.0	11.9	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
3.9	3.9	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
3.7	7.5	GO:0007500	mesodermal cell fate determination(GO:0007500)
3.7	3.7	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
3.7	14.7	GO:0070141	response to UV-A(GO:0070141)
3.6	10.9	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
3.5	3.5	GO:0050923	regulation of negative chemotaxis(GO:0050923)
3.5	17.3	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
3.4	6.9	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
3.4	10.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
3.4	3.4	GO:0072179	nephric duct formation(GO:0072179)
3.4	13.4	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
3.3	6.6	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
3.3	9.8	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
3.2	6.4	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
3.1	3.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
3.0	6.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
3.0	9.1	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
2.9	8.8	GO:0032808	lacrimal gland development(GO:0032808)
2.9	2.9	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
2.8	11.2	GO:1901889	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
2.8	14.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
2.8	5.5	GO:0071502	cellular response to temperature stimulus(GO:0071502)
2.8	5.5	GO:0010159	specification of organ position(GO:0010159)
2.8	11.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
2.7	5.5	GO:0072070	loop of Henle development(GO:0072070)
2.7	5.4	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
2.7	8.1	GO:0061072	iris morphogenesis(GO:0061072)
2.7	8.1	GO:0010842	retina layer formation(GO:0010842)
2.6	5.3	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
2.6	7.8	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
2.5	5.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
2.5	7.5	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
2.5	2.5	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
2.5	2.5	GO:0003171	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
2.4	2.4	GO:0060430	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
2.4	7.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
2.4	16.8	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
2.4	2.4	GO:0022601	menstrual cycle phase(GO:0022601)
2.3	9.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
2.3	6.9	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
2.3	2.3	GO:0060685	regulation of prostatic bud formation(GO:0060685)
2.3	4.6	GO:0060438	trachea development(GO:0060438)
2.3	15.8	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
2.3	2.3	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
2.2	2.2	GO:0045636	regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942)
2.2	2.2	GO:0045992	negative regulation of embryonic development(GO:0045992)
2.2	2.2	GO:0060592	mammary gland formation(GO:0060592)
2.2	8.7	GO:0060013	righting reflex(GO:0060013)
2.2	8.7	GO:0097531	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
2.2	8.6	GO:0010665	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
2.1	10.6	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
2.1	4.2	GO:0060534	trachea cartilage development(GO:0060534) trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
2.1	4.2	GO:0007028	cytoplasm organization(GO:0007028)
2.1	6.3	GO:0007621	negative regulation of female receptivity(GO:0007621)
2.1	4.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
2.0	10.2	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
2.0	6.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
2.0	15.9	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
2.0	2.0	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
2.0	5.9	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
1.9	1.9	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
1.9	7.7	GO:0010955	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
1.9	1.9	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
1.9	1.9	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
1.9	19.0	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
1.9	3.8	GO:0048485	sympathetic nervous system development(GO:0048485)
1.9	7.5	GO:0070208	protein heterotrimerization(GO:0070208)
1.8	7.4	GO:0008218	bioluminescence(GO:0008218)
1.8	1.8	GO:0042637	catagen(GO:0042637)
1.8	14.5	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
1.8	5.4	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.8	3.6	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
1.8	10.6	GO:0016264	gap junction assembly(GO:0016264)
1.7	5.2	GO:0034201	response to oleic acid(GO:0034201)
1.7	1.7	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
1.7	6.9	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.7	5.1	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.7	3.4	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
1.7	5.1	GO:0009648	photoperiodism(GO:0009648)
1.7	3.3	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
1.7	9.9	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
1.7	5.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
1.6	4.9	GO:0009756	carbohydrate mediated signaling(GO:0009756)
1.6	6.6	GO:0051541	elastin metabolic process(GO:0051541)
1.6	9.9	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
1.6	9.9	GO:0031641	regulation of myelination(GO:0031641)
1.6	4.9	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
1.6	3.3	GO:0015868	purine ribonucleotide transport(GO:0015868)
1.6	3.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
1.6	4.9	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
1.6	9.7	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
1.6	4.8	GO:0050807	regulation of synapse organization(GO:0050807)
1.6	20.8	GO:0035329	hippo signaling(GO:0035329)
1.6	3.2	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
1.6	4.8	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
1.6	7.9	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
1.6	4.8	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
1.6	3.2	GO:0043113	receptor clustering(GO:0043113)
1.6	1.6	GO:0060259	regulation of feeding behavior(GO:0060259)
1.6	4.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.5	7.7	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
1.5	9.2	GO:0055003	cardiac myofibril assembly(GO:0055003)
1.5	7.6	GO:0090083	regulation of inclusion body assembly(GO:0090083)
1.5	4.6	GO:0021542	dentate gyrus development(GO:0021542)
1.5	3.0	GO:0001880	Mullerian duct regression(GO:0001880)
1.5	3.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
1.5	5.9	GO:0048048	embryonic eye morphogenesis(GO:0048048)
1.5	17.6	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
1.5	5.8	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
1.5	4.4	GO:0022605	oogenesis stage(GO:0022605)
1.4	4.3	GO:0045112	integrin biosynthetic process(GO:0045112)
1.4	26.0	GO:0009954	proximal/distal pattern formation(GO:0009954)
1.4	1.4	GO:0060214	endocardium formation(GO:0060214)
1.4	1.4	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.4	4.3	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
1.4	1.4	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
1.4	4.3	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.4	4.3	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
1.4	1.4	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
1.4	2.8	GO:0050773	regulation of dendrite development(GO:0050773)
1.4	7.0	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
1.4	6.9	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
1.4	2.8	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
1.4	5.5	GO:0032455	nerve growth factor processing(GO:0032455)
1.4	5.5	GO:0061029	eyelid development in camera-type eye(GO:0061029)
1.4	4.1	GO:0070092	regulation of glucagon secretion(GO:0070092)
1.4	2.7	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
1.4	1.4	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
1.4	8.2	GO:0015871	choline transport(GO:0015871)
1.3	2.7	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
1.3	2.7	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
1.3	1.3	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.3	8.0	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
1.3	18.6	GO:0007528	neuromuscular junction development(GO:0007528)
1.3	9.2	GO:0006198	cAMP catabolic process(GO:0006198)
1.3	1.3	GO:0060437	lung growth(GO:0060437)
1.3	3.9	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) camera-type eye photoreceptor cell differentiation(GO:0060219)
1.3	2.6	GO:0060453	regulation of gastric acid secretion(GO:0060453)
1.3	2.6	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
1.3	3.8	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
1.3	2.5	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
1.3	6.3	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
1.3	2.5	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
1.3	2.5	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
1.3	10.1	GO:0099518	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
1.2	1.2	GO:0002246	wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
1.2	9.9	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
1.2	8.6	GO:0021781	glial cell fate commitment(GO:0021781)
1.2	3.7	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
1.2	1.2	GO:0046958	nonassociative learning(GO:0046958)
1.2	3.6	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.2	18.2	GO:0030199	collagen fibril organization(GO:0030199)
1.2	2.4	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
1.2	2.4	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
1.2	2.4	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
1.2	9.4	GO:0042474	middle ear morphogenesis(GO:0042474)
1.2	3.5	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
1.2	1.2	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.2	8.2	GO:0009404	toxin metabolic process(GO:0009404)
1.2	7.0	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
1.2	3.5	GO:0016081	synaptic vesicle docking(GO:0016081)
1.2	3.5	GO:0048738	cardiac muscle tissue development(GO:0048738)
1.1	4.5	GO:0006991	response to sterol depletion(GO:0006991)
1.1	2.3	GO:0003310	pancreatic A cell differentiation(GO:0003310)
1.1	3.3	GO:0032288	myelin assembly(GO:0032288)
1.1	1.1	GO:0021854	hypothalamus development(GO:0021854)
1.1	17.6	GO:0008038	neuron recognition(GO:0008038)
1.1	4.4	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
1.1	2.2	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
1.1	1.1	GO:0046083	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
1.1	4.3	GO:0051602	response to electrical stimulus(GO:0051602)
1.1	1.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
1.1	4.3	GO:0048333	mesodermal cell differentiation(GO:0048333)
1.1	3.2	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
1.1	4.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
1.1	6.4	GO:0006477	protein sulfation(GO:0006477)
1.1	1.1	GO:0033079	immature T cell proliferation(GO:0033079)
1.0	6.3	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
1.0	1.0	GO:0018126	protein hydroxylation(GO:0018126)
1.0	8.3	GO:0006108	malate metabolic process(GO:0006108)
1.0	5.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
1.0	2.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
1.0	1.0	GO:0003161	cardiac conduction system development(GO:0003161)
1.0	4.1	GO:0001757	somite specification(GO:0001757)
1.0	2.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
1.0	2.0	GO:0021800	cerebral cortex tangential migration(GO:0021800)
1.0	6.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
1.0	6.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
1.0	1.0	GO:0043114	regulation of vascular permeability(GO:0043114)
1.0	3.0	GO:0071398	cellular response to fatty acid(GO:0071398)
1.0	3.0	GO:0021517	ventral spinal cord development(GO:0021517)
1.0	6.9	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
1.0	2.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
1.0	3.0	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
1.0	2.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
1.0	2.9	GO:0098868	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
1.0	4.9	GO:0002076	osteoblast development(GO:0002076)
1.0	2.0	GO:0048799	organ maturation(GO:0048799) bone maturation(GO:0070977)
1.0	2.9	GO:0021873	forebrain neuroblast division(GO:0021873)
1.0	6.7	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
1.0	3.8	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.9	3.8	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.9	1.9	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.9	0.9	GO:1905145	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.9	0.9	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.9	2.8	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.9	0.9	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.9	3.7	GO:0090102	cochlea development(GO:0090102)
0.9	1.9	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.9	4.6	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.9	1.9	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.9	8.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.9	0.9	GO:0071294	cellular response to zinc ion(GO:0071294)
0.9	3.6	GO:0070327	thyroid hormone transport(GO:0070327)
0.9	2.7	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.9	5.4	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.9	2.7	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.9	4.4	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.9	2.6	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.9	5.3	GO:0016540	protein autoprocessing(GO:0016540)
0.9	0.9	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043281)
0.9	9.7	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.9	1.8	GO:0031622	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.9	7.0	GO:0015732	prostaglandin transport(GO:0015732)
0.9	5.2	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.9	2.6	GO:0008215	spermine metabolic process(GO:0008215)
0.9	4.3	GO:0050919	negative chemotaxis(GO:0050919)
0.9	2.6	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.9	5.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.9	0.9	GO:0021591	ventricular system development(GO:0021591)
0.9	0.9	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934)
0.9	0.9	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.8	11.9	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.8	4.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.8	2.5	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.8	3.4	GO:0021571	rhombomere 5 development(GO:0021571)
0.8	3.4	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.8	5.0	GO:0048268	clathrin coat assembly(GO:0048268)
0.8	1.7	GO:0006106	fumarate metabolic process(GO:0006106)
0.8	3.3	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.8	2.5	GO:0050432	catecholamine secretion(GO:0050432)
0.8	2.5	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.8	3.3	GO:0015802	basic amino acid transport(GO:0015802)
0.8	4.1	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.8	6.5	GO:0007530	sex determination(GO:0007530)
0.8	7.3	GO:0009650	UV protection(GO:0009650)
0.8	2.4	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.8	2.4	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.8	9.7	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.8	0.8	GO:0071731	response to nitric oxide(GO:0071731)
0.8	1.6	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.8	1.6	GO:0048566	embryonic digestive tract development(GO:0048566)
0.8	2.4	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.8	8.6	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.8	0.8	GO:0060435	bronchiole development(GO:0060435)
0.8	0.8	GO:0046952	ketone body catabolic process(GO:0046952)
0.8	1.6	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.8	0.8	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.8	0.8	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.8	1.5	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.8	21.3	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.8	2.3	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.8	1.5	GO:0048820	hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.8	7.5	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.7	2.2	GO:0014003	oligodendrocyte development(GO:0014003)
0.7	3.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.7	3.7	GO:0008347	glial cell migration(GO:0008347)
0.7	6.6	GO:0051017	actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.7	2.2	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.7	5.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.7	1.5	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.7	2.2	GO:0033197	response to vitamin E(GO:0033197)
0.7	3.6	GO:0006837	serotonin transport(GO:0006837)
0.7	13.8	GO:0048489	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.7	5.8	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.7	1.5	GO:0050955	thermoception(GO:0050955)
0.7	3.6	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.7	2.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.7	4.3	GO:0009629	response to gravity(GO:0009629)
0.7	12.2	GO:0030574	collagen catabolic process(GO:0030574)
0.7	10.1	GO:0030815	negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818)
0.7	5.0	GO:0030252	growth hormone secretion(GO:0030252)
0.7	4.3	GO:0007616	long-term memory(GO:0007616)
0.7	2.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.7	5.0	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.7	0.7	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.7	2.8	GO:0016266	O-glycan processing(GO:0016266)
0.7	3.5	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.7	6.4	GO:0048265	response to pain(GO:0048265)
0.7	8.5	GO:0001893	maternal placenta development(GO:0001893)
0.7	3.5	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.7	7.7	GO:0001709	cell fate determination(GO:0001709)
0.7	3.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.7	6.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.7	4.2	GO:0032376	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.7	2.8	GO:0060009	Sertoli cell development(GO:0060009)
0.7	3.4	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.7	4.8	GO:0021516	dorsal spinal cord development(GO:0021516)
0.7	2.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.7	2.7	GO:0030321	transepithelial chloride transport(GO:0030321)
0.7	5.4	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.7	0.7	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.7	8.8	GO:0014823	response to activity(GO:0014823)
0.7	5.4	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.7	4.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.7	0.7	GO:0055057	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.7	10.7	GO:0045103	intermediate filament-based process(GO:0045103)
0.7	2.0	GO:0070528	protein kinase C signaling(GO:0070528)
0.7	1.3	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.7	0.7	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.7	4.0	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.7	2.7	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.7	10.0	GO:0006940	regulation of smooth muscle contraction(GO:0006940)
0.7	2.0	GO:0034214	protein hexamerization(GO:0034214)
0.7	3.3	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.7	2.0	GO:0030091	protein repair(GO:0030091)
0.7	9.2	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.7	46.5	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.7	9.1	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.6	7.1	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.6	1.3	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.6	0.6	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.6	1.3	GO:0030259	lipid glycosylation(GO:0030259)
0.6	0.6	GO:0060008	Sertoli cell differentiation(GO:0060008)
0.6	3.1	GO:0007549	dosage compensation(GO:0007549)
0.6	1.9	GO:0006657	CDP-choline pathway(GO:0006657)
0.6	7.5	GO:0007613	memory(GO:0007613)
0.6	4.9	GO:0015671	oxygen transport(GO:0015671)
0.6	1.8	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.6	0.6	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.6	8.5	GO:0035195	gene silencing by miRNA(GO:0035195)
0.6	1.2	GO:0051788	response to misfolded protein(GO:0051788)
0.6	1.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.6	4.2	GO:0006884	cell volume homeostasis(GO:0006884)
0.6	3.0	GO:0043277	apoptotic cell clearance(GO:0043277)
0.6	9.6	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.6	2.4	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.6	1.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.6	3.0	GO:0046541	saliva secretion(GO:0046541)
0.6	1.2	GO:0060039	pericardium development(GO:0060039)
0.6	13.0	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6	1.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.6	0.6	GO:0071548	response to dexamethasone(GO:0071548)
0.6	0.6	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.6	4.1	GO:0018345	protein palmitoylation(GO:0018345)
0.6	0.6	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.6	1.7	GO:0008354	germ cell migration(GO:0008354)
0.6	0.6	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.6	2.3	GO:0007622	rhythmic behavior(GO:0007622)
0.6	0.6	GO:0060174	limb bud formation(GO:0060174)
0.6	0.6	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.6	1.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.6	2.8	GO:0030325	adrenal gland development(GO:0030325)
0.6	1.7	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.6	68.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.6	1.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.6	3.4	GO:0048663	neuron fate commitment(GO:0048663)
0.6	3.4	GO:0072163	ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.6	8.9	GO:0001764	neuron migration(GO:0001764)
0.6	23.4	GO:0031424	keratinization(GO:0031424)
0.6	0.6	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.5	1.6	GO:0032098	regulation of appetite(GO:0032098)
0.5	0.5	GO:0031650	regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.5	2.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.5	1.6	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.5	1.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.5	1.6	GO:0071800	podosome assembly(GO:0071800)
0.5	0.5	GO:0001885	endothelial cell development(GO:0001885)
0.5	3.7	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.5	4.3	GO:0007405	neuroblast proliferation(GO:0007405)
0.5	142.4	GO:0007409	axonogenesis(GO:0007409)
0.5	1.6	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.5	2.6	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.5	2.6	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.5	33.2	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.5	1.6	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5	3.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.5	4.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.5	3.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.5	0.5	GO:0001705	ectoderm formation(GO:0001705)
0.5	4.6	GO:0034605	cellular response to heat(GO:0034605)
0.5	2.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.5	1.0	GO:0016246	RNA interference(GO:0016246)
0.5	1.5	GO:0005984	disaccharide metabolic process(GO:0005984)
0.5	1.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.5	0.5	GO:0006642	triglyceride mobilization(GO:0006642)
0.5	0.5	GO:0021510	spinal cord development(GO:0021510)
0.5	4.5	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.5	8.8	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.5	1.9	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.5	2.4	GO:0048286	lung alveolus development(GO:0048286)
0.5	0.5	GO:0043084	penile erection(GO:0043084)
0.5	0.5	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.5	3.3	GO:0021987	cerebral cortex development(GO:0021987)
0.5	0.5	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.5	0.5	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.5	0.9	GO:0060014	granulosa cell differentiation(GO:0060014)
0.5	1.9	GO:0006538	glutamate catabolic process(GO:0006538)
0.5	2.8	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.5	1.4	GO:0044803	multi-organism membrane organization(GO:0044803)
0.5	1.4	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5	0.5	GO:0001660	fever generation(GO:0001660)
0.5	0.9	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.5	2.7	GO:0035510	DNA dealkylation(GO:0035510)
0.4	1.3	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.4	2.2	GO:0031345	negative regulation of neuron projection development(GO:0010977) negative regulation of cell projection organization(GO:0031345)
0.4	3.5	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.4	1.3	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4	5.2	GO:0032400	melanosome localization(GO:0032400)
0.4	2.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.4	2.6	GO:0015904	tetracycline transport(GO:0015904)
0.4	58.2	GO:0006813	potassium ion transport(GO:0006813)
0.4	1.3	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.4	3.4	GO:0046386	deoxyribose phosphate catabolic process(GO:0046386)
0.4	1.3	GO:0007512	adult heart development(GO:0007512)
0.4	1.7	GO:0008088	axo-dendritic transport(GO:0008088)
0.4	0.9	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.4	1.3	GO:0045980	negative regulation of nucleotide metabolic process(GO:0045980)
0.4	8.0	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.4	2.1	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.4	3.4	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.4	7.1	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.4	8.8	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.4	1.7	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.4	1.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.4	7.1	GO:0031032	actomyosin structure organization(GO:0031032)
0.4	1.6	GO:0043457	regulation of cellular respiration(GO:0043457)
0.4	4.9	GO:0030810	positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.4	4.1	GO:0046888	negative regulation of hormone secretion(GO:0046888)
0.4	2.4	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.4	2.0	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.4	2.8	GO:0033189	response to vitamin A(GO:0033189)
0.4	0.4	GO:0071320	cellular response to cAMP(GO:0071320)
0.4	1.2	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.4	4.8	GO:0015701	bicarbonate transport(GO:0015701)
0.4	1.6	GO:0043276	anoikis(GO:0043276)
0.4	0.8	GO:0007494	midgut development(GO:0007494)
0.4	0.8	GO:0042693	muscle cell fate commitment(GO:0042693)
0.4	0.4	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.4	0.8	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.4	1.6	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.4	1.5	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.4	3.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.4	0.4	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.4	0.4	GO:0035590	purinergic receptor signaling pathway(GO:0035587) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.4	6.8	GO:0007266	Rho protein signal transduction(GO:0007266)
0.4	2.3	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.4	0.4	GO:0051955	regulation of amino acid transport(GO:0051955)
0.4	0.8	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.4	0.4	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.4	1.8	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.4	0.4	GO:0042220	response to cocaine(GO:0042220)
0.4	2.5	GO:0048839	inner ear development(GO:0048839)
0.4	0.4	GO:0070423	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.4	1.1	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4	0.4	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.4	1.4	GO:0050872	white fat cell differentiation(GO:0050872)
0.4	0.4	GO:0010269	response to selenium ion(GO:0010269)
0.4	3.9	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.3	0.7	GO:0019532	oxalate transport(GO:0019532)
0.3	2.8	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.3	4.8	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.3	0.3	GO:0031529	ruffle organization(GO:0031529)
0.3	1.0	GO:0046655	folic acid metabolic process(GO:0046655)
0.3	2.0	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.3	4.4	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3	0.3	GO:0090400	stress-induced premature senescence(GO:0090400)
0.3	1.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.3	0.3	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.3	2.3	GO:0060415	muscle tissue morphogenesis(GO:0060415)
0.3	0.7	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.3	2.0	GO:0042730	fibrinolysis(GO:0042730)
0.3	2.0	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.3	7.5	GO:0006730	one-carbon metabolic process(GO:0006730)
0.3	0.6	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.3	1.3	GO:0061053	somite development(GO:0061053)
0.3	0.3	GO:0010002	cardioblast differentiation(GO:0010002)
0.3	0.3	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3	4.1	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.3	0.6	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.3	0.9	GO:0048388	endosomal lumen acidification(GO:0048388)
0.3	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.3	3.5	GO:0046415	urate metabolic process(GO:0046415)
0.3	0.6	GO:0045446	endothelial cell differentiation(GO:0045446)
0.3	26.4	GO:0001525	angiogenesis(GO:0001525)
0.3	0.6	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.3	1.9	GO:0046326	positive regulation of glucose import(GO:0046326)
0.3	4.0	GO:0006821	chloride transport(GO:0006821)
0.3	0.6	GO:0043587	tongue morphogenesis(GO:0043587)
0.3	0.9	GO:0034063	stress granule assembly(GO:0034063)
0.3	0.9	GO:0019695	choline metabolic process(GO:0019695)
0.3	4.4	GO:0046847	filopodium assembly(GO:0046847)
0.3	0.9	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.3	0.6	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.3	0.3	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.3	2.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.3	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.3	0.3	GO:0048713	regulation of oligodendrocyte differentiation(GO:0048713)
0.3	5.0	GO:0048706	embryonic skeletal system development(GO:0048706)
0.3	1.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.3	0.6	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.3	0.3	GO:0003156	regulation of organ formation(GO:0003156)
0.3	1.2	GO:0045445	myoblast differentiation(GO:0045445)
0.3	0.3	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
0.3	7.2	GO:0051291	protein heterooligomerization(GO:0051291)
0.3	4.9	GO:0008584	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.3	0.9	GO:0034629	cellular protein complex localization(GO:0034629)
0.3	20.6	GO:0006814	sodium ion transport(GO:0006814)
0.3	1.4	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.3	0.8	GO:0000966	RNA 5'-end processing(GO:0000966)
0.3	1.1	GO:0043588	skin development(GO:0043588)
0.3	0.5	GO:0071318	cellular response to ATP(GO:0071318)
0.3	1.6	GO:0051101	regulation of DNA binding(GO:0051101)
0.3	1.6	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.3	1.1	GO:0010226	response to lithium ion(GO:0010226)
0.3	0.5	GO:0006560	proline metabolic process(GO:0006560)
0.3	2.9	GO:0045995	regulation of embryonic development(GO:0045995)
0.3	4.2	GO:0019433	triglyceride catabolic process(GO:0019433)
0.3	1.3	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3	1.0	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.3	1.8	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.3	0.3	GO:0015705	iodide transport(GO:0015705)
0.3	0.3	GO:0031639	plasminogen activation(GO:0031639)
0.3	0.3	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.3	2.3	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.3	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.3	0.8	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.3	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	0.5	GO:0002328	pro-B cell differentiation(GO:0002328)
0.2	1.0	GO:0090130	tissue migration(GO:0090130)
0.2	1.0	GO:0050905	neuromuscular process(GO:0050905)
0.2	2.2	GO:1900182	positive regulation of protein import into nucleus(GO:0042307) positive regulation of protein localization to nucleus(GO:1900182) positive regulation of protein import(GO:1904591)
0.2	0.7	GO:0016265	obsolete death(GO:0016265)
0.2	1.0	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.2	1.7	GO:0001843	neural tube closure(GO:0001843)
0.2	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	0.7	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	1.2	GO:0001573	ganglioside metabolic process(GO:0001573)
0.2	0.2	GO:0032095	regulation of response to food(GO:0032095)
0.2	1.4	GO:0007340	acrosome reaction(GO:0007340)
0.2	0.9	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.2	1.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.2	2.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2	0.2	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.2	1.8	GO:0045807	positive regulation of endocytosis(GO:0045807)
0.2	0.5	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.2	1.6	GO:0051205	protein insertion into membrane(GO:0051205)
0.2	0.2	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.2	1.6	GO:0048813	dendrite morphogenesis(GO:0048813)
0.2	0.5	GO:0007431	salivary gland development(GO:0007431)
0.2	0.2	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.2	6.4	GO:0050890	cognition(GO:0050890)
0.2	0.2	GO:0032465	regulation of cytokinesis(GO:0032465)
0.2	4.5	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2	1.8	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.2	1.6	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2	0.9	GO:0000052	citrulline metabolic process(GO:0000052)
0.2	4.2	GO:0070252	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) actin-mediated cell contraction(GO:0070252)
0.2	0.4	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.2	1.3	GO:0043525	positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2	1.1	GO:0050931	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.2	0.7	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2	0.2	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.2	0.7	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2	0.2	GO:0010171	body morphogenesis(GO:0010171)
0.2	2.6	GO:0030509	BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.2	1.7	GO:0018149	peptide cross-linking(GO:0018149)
0.2	0.2	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.2	0.9	GO:0030488	tRNA methylation(GO:0030488)
0.2	7.0	GO:0008544	epidermis development(GO:0008544)
0.2	4.9	GO:0006308	DNA catabolic process(GO:0006308)
0.2	2.5	GO:0043968	histone H2A acetylation(GO:0043968)
0.2	0.6	GO:0050667	homocysteine metabolic process(GO:0050667)
0.2	3.2	GO:0048736	appendage development(GO:0048736) limb development(GO:0060173)
0.2	1.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2	0.6	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	5.2	GO:0007588	excretion(GO:0007588)
0.2	2.5	GO:0007368	determination of left/right symmetry(GO:0007368)
0.2	5.2	GO:0017148	negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.2	1.0	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.2	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.2	1.6	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.2	2.1	GO:0009311	oligosaccharide metabolic process(GO:0009311)
0.2	0.2	GO:0042268	regulation of cytolysis(GO:0042268)
0.2	0.6	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.2	0.6	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.2	1.0	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.2	1.2	GO:0006937	regulation of muscle contraction(GO:0006937)
0.2	3.4	GO:0051216	cartilage development(GO:0051216)
0.2	0.2	GO:1901160	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.2	6.2	GO:0030111	regulation of Wnt signaling pathway(GO:0030111)
0.2	0.2	GO:0003382	epithelial cell morphogenesis(GO:0003382)
0.2	1.6	GO:0015074	DNA integration(GO:0015074)
0.2	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2	0.4	GO:0007100	mitotic centrosome separation(GO:0007100)
0.2	1.5	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.2	0.8	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	0.2	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.2	0.8	GO:0009409	response to cold(GO:0009409)
0.2	0.6	GO:0030901	midbrain development(GO:0030901)
0.2	0.2	GO:0090311	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.2	0.4	GO:0009106	lipoate metabolic process(GO:0009106)
0.2	0.8	GO:0043030	regulation of macrophage activation(GO:0043030)
0.2	1.5	GO:0008272	sulfate transport(GO:0008272)
0.2	7.0	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.2	0.6	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2	2.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.2	16.9	GO:0043087	regulation of GTPase activity(GO:0043087)
0.2	0.2	GO:0006817	phosphate ion transport(GO:0006817)
0.2	1.8	GO:0007141	male meiosis I(GO:0007141)
0.2	2.1	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.2	1.5	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.2	0.8	GO:0042438	melanin biosynthetic process(GO:0042438)
0.2	0.2	GO:0032674	interleukin-5 production(GO:0032634) regulation of interleukin-5 production(GO:0032674)
0.2	0.3	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.2	0.8	GO:0042246	tissue regeneration(GO:0042246)
0.2	0.3	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.2	0.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.2	0.3	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.2	0.5	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.2	1.2	GO:0007566	embryo implantation(GO:0007566)
0.2	0.8	GO:0070207	protein homotrimerization(GO:0070207)
0.2	0.2	GO:0031268	pseudopodium organization(GO:0031268)
0.2	0.9	GO:0033273	response to vitamin(GO:0033273)
0.1	1.0	GO:0015695	organic cation transport(GO:0015695)
0.1	0.4	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.1	GO:0048483	autonomic nervous system development(GO:0048483)
0.1	0.7	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.3	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	0.6	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.9	GO:0018065	protein-cofactor linkage(GO:0018065)
0.1	0.1	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.1	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.1	0.3	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.1	0.1	GO:1903727	positive regulation of phospholipid metabolic process(GO:1903727)
0.1	0.5	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1	0.5	GO:0042574	retinal metabolic process(GO:0042574)
0.1	0.8	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	0.4	GO:0001508	action potential(GO:0001508)
0.1	0.1	GO:0048588	developmental cell growth(GO:0048588)
0.1	0.1	GO:0002021	response to dietary excess(GO:0002021)
0.1	0.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.4	GO:0006983	ER overload response(GO:0006983)
0.1	0.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	9.7	GO:0061061	muscle structure development(GO:0061061)
0.1	0.4	GO:0006622	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.1	0.1	GO:0070254	mucus secretion(GO:0070254)
0.1	0.7	GO:0030100	regulation of endocytosis(GO:0030100)
0.1	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.1	2.9	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1	0.1	GO:2000117	negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.1	0.1	GO:0014888	striated muscle adaptation(GO:0014888)
0.1	0.2	GO:0030878	thyroid gland development(GO:0030878)
0.1	6.4	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.1	GO:0045821	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.1	5.3	GO:0034329	cell junction assembly(GO:0034329)
0.1	1.8	GO:0007626	locomotory behavior(GO:0007626)
0.1	1.5	GO:0030216	keratinocyte differentiation(GO:0030216)
0.1	1.8	GO:0048477	oogenesis(GO:0048477)
0.1	0.3	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.2	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.1	0.1	GO:0045056	transcytosis(GO:0045056)
0.1	0.2	GO:0060056	mammary gland involution(GO:0060056)
0.1	2.8	GO:0031175	neuron projection development(GO:0031175)
0.1	0.1	GO:0006907	pinocytosis(GO:0006907)
0.1	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1	1.0	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.1	GO:0072234	metanephric tubule development(GO:0072170) metanephric epithelium development(GO:0072207) metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.1	0.2	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1	3.6	GO:0030308	negative regulation of cell growth(GO:0030308)
0.1	1.7	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	0.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.1	0.3	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.1	0.4	GO:0046040	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.1	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.1	0.3	GO:0034105	positive regulation of tissue remodeling(GO:0034105)
0.1	0.2	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.1	GO:0051781	positive regulation of cell division(GO:0051781)
0.1	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.1	0.4	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.6	GO:0009268	response to pH(GO:0009268)
0.1	0.4	GO:0044241	lipid digestion(GO:0044241)
0.1	0.1	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.1	0.1	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.3	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.3	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.1	0.4	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.4	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.1	0.3	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.8	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.1	GO:0048854	brain morphogenesis(GO:0048854)
0.1	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	0.1	GO:0032924	activin receptor signaling pathway(GO:0032924) regulation of activin receptor signaling pathway(GO:0032925)
0.1	0.3	GO:0006857	oligopeptide transport(GO:0006857)
0.1	0.1	GO:0048532	anatomical structure arrangement(GO:0048532)
0.1	0.4	GO:0015858	nucleoside transport(GO:0015858)
0.1	5.1	GO:0007018	microtubule-based movement(GO:0007018)
0.1	0.6	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.1	22.5	GO:0007399	nervous system development(GO:0007399)
0.1	0.2	GO:0042417	dopamine metabolic process(GO:0042417)
0.1	0.1	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.1	0.2	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.1	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	0.7	GO:0009791	post-embryonic development(GO:0009791)
0.1	0.1	GO:0035272	exocrine system development(GO:0035272)
0.1	2.2	GO:0031638	zymogen activation(GO:0031638)
0.1	0.6	GO:0006476	protein deacetylation(GO:0006476)
0.1	1.4	GO:0006898	receptor-mediated endocytosis(GO:0006898)
0.1	0.1	GO:0048066	developmental pigmentation(GO:0048066)
0.1	0.2	GO:0015810	C4-dicarboxylate transport(GO:0015740) aspartate transport(GO:0015810)
0.1	0.5	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090101)
0.1	0.1	GO:0051588	regulation of neurotransmitter transport(GO:0051588)
0.1	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1	0.1	GO:0048539	bone marrow development(GO:0048539)
0.1	0.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	0.1	GO:0015844	monoamine transport(GO:0015844)
0.1	0.6	GO:0010952	positive regulation of peptidase activity(GO:0010952)
0.1	0.4	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.1	0.2	GO:0030277	epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.1	1.4	GO:0015682	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.1	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.1	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.1	1.9	GO:0006936	muscle contraction(GO:0006936)
0.1	0.6	GO:0042255	ribosome assembly(GO:0042255)
0.1	0.4	GO:0043473	pigmentation(GO:0043473)
0.1	0.4	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.2	GO:0072595	maintenance of protein localization in organelle(GO:0072595)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.0	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0032106	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0007620	copulation(GO:0007620)
0.0	0.2	GO:1900046	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.3	GO:0009712	catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0	0.2	GO:1901880	negative regulation of protein depolymerization(GO:1901880)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.1	GO:0010039	response to iron ion(GO:0010039)
0.0	0.0	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.0	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	3.1	GO:0007601	visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0	0.1	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.0	0.1	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0018958	phenol-containing compound metabolic process(GO:0018958)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.0	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.0	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0019236	response to pheromone(GO:0019236)
0.0	0.0	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.3	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0051339	regulation of lyase activity(GO:0051339)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0070989	oxidative demethylation(GO:0070989)
0.0	0.0	GO:0050892	intestinal absorption(GO:0050892)
0.0	0.1	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.0	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.3	GO:0046328	regulation of JNK cascade(GO:0046328)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.6	10.9	GO:0043259	laminin-10 complex(GO:0043259)
3.3	19.9	GO:0001527	microfibril(GO:0001527)
3.2	9.5	GO:0030934	anchoring collagen complex(GO:0030934)
3.1	3.1	GO:0043260	laminin-11 complex(GO:0043260)
2.8	16.9	GO:0010369	chromocenter(GO:0010369)
2.7	11.0	GO:0005606	laminin-1 complex(GO:0005606)
2.6	5.2	GO:0043083	synaptic cleft(GO:0043083)
2.5	7.5	GO:0033270	paranode region of axon(GO:0033270)
2.4	7.2	GO:0005588	collagen type V trimer(GO:0005588)
2.0	6.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
2.0	10.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
2.0	11.9	GO:0005587	collagen type IV trimer(GO:0005587)
1.9	21.2	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
1.9	5.7	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.9	5.6	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.9	9.3	GO:0071437	invadopodium(GO:0071437)
1.8	5.5	GO:0031527	filopodium membrane(GO:0031527)
1.8	10.9	GO:0031512	motile primary cilium(GO:0031512)
1.8	5.3	GO:0070852	cell body fiber(GO:0070852)
1.7	1.7	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
1.6	12.9	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
1.5	25.8	GO:0009925	basal plasma membrane(GO:0009925)
1.5	26.9	GO:0030057	desmosome(GO:0030057)
1.5	4.4	GO:0005899	insulin receptor complex(GO:0005899)
1.5	8.9	GO:0016012	sarcoglycan complex(GO:0016012)
1.5	5.9	GO:0005915	zonula adherens(GO:0005915)
1.5	5.8	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
1.4	2.8	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
1.4	15.5	GO:0031528	microvillus membrane(GO:0031528)
1.4	7.0	GO:0031258	lamellipodium membrane(GO:0031258)
1.4	25.0	GO:0005913	cell-cell adherens junction(GO:0005913)
1.3	2.7	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
1.3	10.6	GO:0043034	costamere(GO:0043034)
1.3	3.8	GO:0030673	axolemma(GO:0030673)
1.2	25.2	GO:0005581	collagen trimer(GO:0005581)
1.2	7.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
1.2	3.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
1.1	24.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
1.1	4.5	GO:0031045	dense core granule(GO:0031045)
1.1	70.5	GO:0030426	growth cone(GO:0030426)
1.1	3.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
1.1	269.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
1.0	3.1	GO:0032591	dendritic spine membrane(GO:0032591)
1.0	5.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
1.0	4.0	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
1.0	63.5	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.0	9.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.9	11.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.9	2.8	GO:0032449	CBM complex(GO:0032449)
0.9	2.8	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.9	5.6	GO:0001891	phagocytic cup(GO:0001891)
0.9	6.5	GO:0032589	neuron projection membrane(GO:0032589)
0.9	7.4	GO:0030315	T-tubule(GO:0030315)
0.9	1.8	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.9	7.9	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.9	28.5	GO:0042734	presynaptic membrane(GO:0042734)
0.8	3.4	GO:0001740	Barr body(GO:0001740)
0.8	50.6	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.8	2.4	GO:0005883	neurofilament(GO:0005883)
0.8	11.2	GO:0044447	axoneme part(GO:0044447)
0.8	4.8	GO:0005652	nuclear lamina(GO:0005652)
0.7	37.8	GO:0031012	extracellular matrix(GO:0031012)
0.7	3.7	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.7	75.7	GO:0005912	adherens junction(GO:0005912)
0.7	0.7	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.7	1.4	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.7	28.6	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.7	14.2	GO:0005796	Golgi lumen(GO:0005796)
0.7	2.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.6	1.3	GO:0000805	X chromosome(GO:0000805)
0.6	0.6	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.6	0.6	GO:0005641	nuclear envelope lumen(GO:0005641)
0.6	1.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.6	1.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.6	1.7	GO:0032593	insulin-responsive compartment(GO:0032593)
0.6	5.0	GO:0008091	spectrin(GO:0008091)
0.5	12.6	GO:0042383	sarcolemma(GO:0042383)
0.5	10.9	GO:0005884	actin filament(GO:0005884)
0.5	0.5	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.5	18.4	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5	1.0	GO:0030061	mitochondrial crista(GO:0030061)
0.5	15.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.5	3.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.5	16.1	GO:0008021	synaptic vesicle(GO:0008021)
0.5	2.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.4	1.8	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.4	26.7	GO:0005911	cell-cell junction(GO:0005911)
0.4	1.7	GO:0030904	retromer complex(GO:0030904)
0.4	68.7	GO:0045202	synapse(GO:0045202)
0.4	44.9	GO:0031225	anchored component of membrane(GO:0031225)
0.4	1.6	GO:0034704	calcium channel complex(GO:0034704)
0.4	219.8	GO:0005615	extracellular space(GO:0005615)
0.4	16.6	GO:0030425	dendrite(GO:0030425)
0.4	1.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.4	1.1	GO:0001772	immunological synapse(GO:0001772)
0.4	6.3	GO:0016460	myosin II complex(GO:0016460)
0.4	2.6	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.4	2.6	GO:0008290	F-actin capping protein complex(GO:0008290)
0.4	3.9	GO:0071565	nBAF complex(GO:0071565)
0.4	301.3	GO:0005887	integral component of plasma membrane(GO:0005887)
0.4	3.5	GO:0030175	filopodium(GO:0030175)
0.3	0.7	GO:0042589	zymogen granule membrane(GO:0042589)
0.3	1.4	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.3	3.7	GO:0030286	dynein complex(GO:0030286)
0.3	80.7	GO:0005667	transcription factor complex(GO:0005667)
0.3	1.6	GO:0044421	extracellular region part(GO:0044421)
0.3	1.0	GO:0032806	carboxy-terminal domain protein kinase complex(GO:0032806)
0.3	5.4	GO:0030018	Z disc(GO:0030018)
0.3	1.9	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.3	0.9	GO:0030008	TRAPP complex(GO:0030008)
0.3	1.8	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3	1.4	GO:0030870	Mre11 complex(GO:0030870)
0.3	1.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.3	3.3	GO:0005833	hemoglobin complex(GO:0005833)
0.3	1.4	GO:0043202	lysosomal lumen(GO:0043202)
0.3	5.0	GO:0005802	trans-Golgi network(GO:0005802)
0.3	9.8	GO:0001726	ruffle(GO:0001726)
0.3	5.9	GO:0034707	chloride channel complex(GO:0034707)
0.3	15.9	GO:0043005	neuron projection(GO:0043005)
0.2	4.2	GO:0005776	autophagosome(GO:0005776)
0.2	0.7	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	1.2	GO:0000801	central element(GO:0000801)
0.2	6.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	14.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.2	1.8	GO:0005861	troponin complex(GO:0005861)
0.2	2.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.2	0.4	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.2	0.7	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.2	3.0	GO:0005811	lipid particle(GO:0005811)
0.2	2.2	GO:0005771	multivesicular body(GO:0005771)
0.2	177.0	GO:0005576	extracellular region(GO:0005576)
0.2	6.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	6.0	GO:0030054	cell junction(GO:0030054)
0.2	4.1	GO:0044449	contractile fiber part(GO:0044449)
0.2	2.3	GO:0031526	brush border membrane(GO:0031526)
0.2	1.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2	0.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.2	0.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.2	1.2	GO:0032421	stereocilium bundle(GO:0032421)
0.2	1.0	GO:0071546	pi-body(GO:0071546)
0.2	0.8	GO:0031262	Ndc80 complex(GO:0031262)
0.2	61.5	GO:0000139	Golgi membrane(GO:0000139)
0.2	0.9	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.2	1.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.2	0.5	GO:0031091	platelet alpha granule(GO:0031091)
0.2	10.9	GO:0005792	obsolete microsome(GO:0005792)
0.2	0.5	GO:0071986	Ragulator complex(GO:0071986)
0.2	0.7	GO:0016328	lateral plasma membrane(GO:0016328)
0.2	2.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	0.5	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.2	0.5	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	10.0	GO:0045177	apical part of cell(GO:0045177)
0.2	0.2	GO:0005826	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.2	0.5	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	408.1	GO:0016021	integral component of membrane(GO:0016021)
0.1	0.7	GO:0033391	chromatoid body(GO:0033391)
0.1	0.3	GO:0031143	pseudopodium(GO:0031143)
0.1	0.4	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.6	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	0.5	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.6	GO:0000796	condensin complex(GO:0000796)
0.1	0.3	GO:0019861	obsolete flagellum(GO:0019861)
0.1	0.5	GO:0001739	sex chromatin(GO:0001739)
0.1	0.1	GO:0016528	sarcoplasm(GO:0016528)
0.1	2.8	GO:0036064	ciliary basal body(GO:0036064)
0.1	0.4	GO:0030686	90S preribosome(GO:0030686)
0.1	0.8	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.1	1.1	GO:0043073	germ cell nucleus(GO:0043073)
0.1	1.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.1	GO:0043209	myelin sheath(GO:0043209)
0.1	0.1	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	4.5	GO:0005929	cilium(GO:0005929)
0.1	1.4	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	1.2	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.3	GO:0031984	organelle subcompartment(GO:0031984)
0.0	3.7	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	2.9	GO:0045095	keratin filament(GO:0045095)
0.0	0.0	GO:0002080	acrosomal membrane(GO:0002080)
0.0	1.3	GO:0005624	obsolete membrane fraction(GO:0005624)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.0	GO:0005875	microtubule associated complex(GO:0005875)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	3.0	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	0.2	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	3.3	GO:0005740	mitochondrial envelope(GO:0005740)
0.0	0.3	GO:0044452	nucleolar part(GO:0044452)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	6.2	GO:0005856	cytoskeleton(GO:0005856)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.8	20.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
4.3	12.9	GO:0030215	semaphorin receptor binding(GO:0030215)
4.1	16.6	GO:0048495	Roundabout binding(GO:0048495)
4.1	12.4	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
3.9	19.4	GO:0017154	semaphorin receptor activity(GO:0017154)
3.7	22.1	GO:0008046	axon guidance receptor activity(GO:0008046)
3.5	10.6	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
3.5	10.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
3.4	10.3	GO:0070324	thyroid hormone binding(GO:0070324)
3.3	9.9	GO:0003680	AT DNA binding(GO:0003680)
3.2	9.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
3.1	15.7	GO:0070700	BMP receptor binding(GO:0070700)
3.0	50.6	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.9	8.6	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
2.7	8.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
2.7	8.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
2.6	18.5	GO:0005110	frizzled-2 binding(GO:0005110)
2.6	23.5	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
2.6	7.7	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
2.6	10.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
2.4	9.7	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
2.4	7.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
2.4	9.4	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
2.3	6.8	GO:0043394	proteoglycan binding(GO:0043394)
2.2	8.9	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
2.2	6.7	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.2	8.8	GO:0070215	obsolete MDM2 binding(GO:0070215)
2.2	6.5	GO:0003987	acetate-CoA ligase activity(GO:0003987)
2.1	6.3	GO:0019215	intermediate filament binding(GO:0019215)
2.1	10.4	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
2.1	6.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
2.1	10.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
2.0	6.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
2.0	6.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
2.0	8.0	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.0	8.0	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
1.9	7.7	GO:0000293	ferric-chelate reductase activity(GO:0000293)
1.9	7.7	GO:0004470	malic enzyme activity(GO:0004470)
1.9	23.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
1.9	11.5	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
1.9	7.6	GO:0004157	dihydropyrimidinase activity(GO:0004157)
1.9	5.7	GO:0008061	chitin binding(GO:0008061)
1.9	9.4	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
1.8	42.5	GO:0017147	Wnt-protein binding(GO:0017147)
1.8	7.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
1.8	10.9	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
1.8	12.6	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
1.8	5.4	GO:0004949	cannabinoid receptor activity(GO:0004949)
1.8	1.8	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.8	5.3	GO:0005113	patched binding(GO:0005113)
1.7	5.1	GO:0050682	AF-2 domain binding(GO:0050682)
1.7	5.1	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
1.7	6.8	GO:0016004	phospholipase activator activity(GO:0016004)
1.7	6.7	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
1.7	6.7	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.7	6.7	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.6	22.9	GO:0031490	chromatin DNA binding(GO:0031490)
1.6	4.8	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
1.6	6.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
1.6	8.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
1.6	4.8	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
1.6	6.4	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.6	4.7	GO:0005042	netrin receptor activity(GO:0005042)
1.6	12.5	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
1.5	119.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
1.5	4.6	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.5	1.5	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
1.5	10.6	GO:0017166	vinculin binding(GO:0017166)
1.5	4.5	GO:0016151	nickel cation binding(GO:0016151)
1.5	3.0	GO:0035254	glutamate receptor binding(GO:0035254)
1.5	5.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.5	4.4	GO:0042577	lipid phosphatase activity(GO:0042577)
1.5	4.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.5	2.9	GO:0030955	potassium ion binding(GO:0030955)
1.4	4.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
1.4	2.8	GO:0004935	adrenergic receptor activity(GO:0004935)
1.4	9.8	GO:0030506	ankyrin binding(GO:0030506)
1.4	5.5	GO:0045499	chemorepellent activity(GO:0045499)
1.4	4.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
1.4	4.1	GO:0034056	estrogen response element binding(GO:0034056)
1.4	15.0	GO:0030553	cGMP binding(GO:0030553)
1.4	8.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
1.3	5.4	GO:0015379	potassium:chloride symporter activity(GO:0015379)
1.3	4.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
1.3	2.7	GO:0043208	glycosphingolipid binding(GO:0043208)
1.3	4.0	GO:0050544	arachidonic acid binding(GO:0050544)
1.3	6.6	GO:0008517	folic acid transporter activity(GO:0008517)
1.3	5.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.3	6.5	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
1.3	1.3	GO:0070644	vitamin D response element binding(GO:0070644)
1.3	7.8	GO:0004887	thyroid hormone receptor activity(GO:0004887)
1.3	3.9	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.3	12.8	GO:0004383	guanylate cyclase activity(GO:0004383)
1.3	10.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
1.2	2.5	GO:0043495	protein anchor(GO:0043495)
1.2	7.5	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
1.2	6.2	GO:0005000	vasopressin receptor activity(GO:0005000)
1.2	7.4	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
1.2	8.6	GO:0042043	neurexin family protein binding(GO:0042043)
1.2	6.1	GO:0048406	nerve growth factor binding(GO:0048406)
1.2	6.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
1.2	3.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
1.2	8.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.2	10.5	GO:0015245	fatty acid transporter activity(GO:0015245)
1.1	13.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
1.1	1.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
1.1	10.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.1	18.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
1.1	9.0	GO:0050780	dopamine receptor binding(GO:0050780)
1.1	4.5	GO:0005227	calcium activated cation channel activity(GO:0005227)
1.1	6.6	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
1.1	3.3	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
1.1	3.3	GO:0004103	choline kinase activity(GO:0004103)
1.1	4.4	GO:0008179	adenylate cyclase binding(GO:0008179)
1.1	1.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
1.1	8.6	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
1.1	1.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
1.1	3.2	GO:0004461	lactose synthase activity(GO:0004461)
1.1	4.3	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.1	3.2	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
1.0	15.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.0	28.2	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
1.0	7.3	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
1.0	14.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.0	9.3	GO:0015385	sodium:proton antiporter activity(GO:0015385)
1.0	10.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
1.0	3.0	GO:0019798	procollagen-proline dioxygenase activity(GO:0019798)
1.0	3.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
1.0	2.9	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.0	6.7	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
1.0	4.8	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.9	2.8	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.9	4.7	GO:0043522	leucine zipper domain binding(GO:0043522)
0.9	8.4	GO:0051378	serotonin binding(GO:0051378)
0.9	2.8	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.9	4.5	GO:0004985	opioid receptor activity(GO:0004985)
0.9	3.6	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.9	5.4	GO:0005112	Notch binding(GO:0005112)
0.9	0.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.9	2.7	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.9	5.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.9	4.5	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.9	0.9	GO:0031420	alkali metal ion binding(GO:0031420)
0.9	7.1	GO:0015643	toxic substance binding(GO:0015643)
0.9	3.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.9	7.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.9	2.6	GO:0004995	tachykinin receptor activity(GO:0004995)
0.9	4.4	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.9	2.6	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.9	18.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.9	2.6	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.9	42.6	GO:0051015	actin filament binding(GO:0051015)
0.9	2.6	GO:0050321	tau-protein kinase activity(GO:0050321)
0.9	5.2	GO:0034235	GPI anchor binding(GO:0034235)
0.9	1.7	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.8	0.8	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.8	3.4	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.8	4.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.8	13.4	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.8	1.7	GO:0045545	syndecan binding(GO:0045545)
0.8	8.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.8	9.7	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.8	2.4	GO:0031849	olfactory receptor binding(GO:0031849)
0.8	4.0	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.8	6.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.8	2.4	GO:0008502	melatonin receptor activity(GO:0008502)
0.8	13.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.8	2.4	GO:0043274	phospholipase binding(GO:0043274)
0.8	3.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.8	3.1	GO:0005522	profilin binding(GO:0005522)
0.8	0.8	GO:0048185	activin binding(GO:0048185)
0.8	5.4	GO:0005272	sodium channel activity(GO:0005272)
0.8	2.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.8	5.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.8	3.8	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.8	8.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.7	12.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.7	10.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.7	3.0	GO:0001784	phosphotyrosine binding(GO:0001784)
0.7	7.3	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.7	2.9	GO:0004111	creatine kinase activity(GO:0004111)
0.7	2.9	GO:0030172	troponin C binding(GO:0030172)
0.7	11.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7	2.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.7	3.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.7	2.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.7	2.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.7	56.9	GO:0008201	heparin binding(GO:0008201)
0.7	5.0	GO:0004016	adenylate cyclase activity(GO:0004016)
0.7	2.1	GO:0035198	miRNA binding(GO:0035198)
0.7	4.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.7	2.8	GO:0032036	myosin heavy chain binding(GO:0032036)
0.7	3.4	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.7	21.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.7	2.7	GO:0030371	translation repressor activity(GO:0030371)
0.7	2.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.7	2.7	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.7	10.8	GO:0004407	histone deacetylase activity(GO:0004407)
0.7	9.3	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.7	14.7	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.7	4.0	GO:0051183	vitamin transporter activity(GO:0051183)
0.7	2.6	GO:0031685	adenosine receptor binding(GO:0031685)
0.6	2.6	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.6	5.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.6	71.0	GO:0008083	growth factor activity(GO:0008083)
0.6	2.5	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.6	6.3	GO:0045296	cadherin binding(GO:0045296)
0.6	5.1	GO:0008242	omega peptidase activity(GO:0008242)
0.6	1.3	GO:0019534	toxin transporter activity(GO:0019534)
0.6	5.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.6	176.3	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.6	1.9	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.6	10.5	GO:0005518	collagen binding(GO:0005518)
0.6	1.9	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.6	1.8	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.6	2.4	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.6	2.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.6	1.2	GO:0004630	phospholipase D activity(GO:0004630)
0.6	1.2	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.6	1.8	GO:0008432	JUN kinase binding(GO:0008432)
0.6	2.9	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.6	1.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.6	2.9	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.6	2.9	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.6	4.6	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.6	2.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.6	1.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.6	2.2	GO:0001515	opioid peptide activity(GO:0001515)
0.6	2.2	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.6	38.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.6	1.7	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.5	1.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.5	2.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.5	3.3	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.5	7.6	GO:0008373	sialyltransferase activity(GO:0008373)
0.5	1.6	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.5	10.8	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.5	4.9	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.5	1.6	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.5	2.6	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.5	1.6	GO:0002060	purine nucleobase binding(GO:0002060)
0.5	7.9	GO:0015026	coreceptor activity(GO:0015026)
0.5	10.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.5	3.7	GO:0030276	clathrin binding(GO:0030276)
0.5	1.6	GO:0002162	dystroglycan binding(GO:0002162)
0.5	2.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.5	1.5	GO:0001968	fibronectin binding(GO:0001968)
0.5	1.5	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.5	2.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5	1.5	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.5	1.5	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.5	1.5	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.5	50.0	GO:0005267	potassium channel activity(GO:0005267)
0.5	4.8	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5	8.2	GO:0032947	protein complex scaffold(GO:0032947)
0.5	1.4	GO:0016805	dipeptidase activity(GO:0016805)
0.5	3.8	GO:0004017	adenylate kinase activity(GO:0004017)
0.5	4.2	GO:0005243	gap junction channel activity(GO:0005243)
0.5	1.9	GO:0051400	BH domain binding(GO:0051400)
0.5	2.8	GO:0017049	GTP-Rho binding(GO:0017049)
0.5	46.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.5	4.6	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.5	1.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.5	1.4	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.5	1.4	GO:0030274	LIM domain binding(GO:0030274)
0.4	1.8	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.4	4.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.4	0.9	GO:0031013	troponin I binding(GO:0031013)
0.4	0.9	GO:0004977	melanocortin receptor activity(GO:0004977)
0.4	6.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.4	0.9	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.4	1.3	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.4	0.9	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.4	1.3	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.4	1.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4	2.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.4	2.6	GO:0042895	tetracycline transporter activity(GO:0008493) antibiotic transporter activity(GO:0042895)
0.4	1.3	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.4	5.1	GO:0017046	peptide hormone binding(GO:0017046)
0.4	1.3	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.4	8.3	GO:0070405	ammonium ion binding(GO:0070405)
0.4	0.8	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.4	0.4	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.4	5.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.4	3.7	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.4	5.3	GO:0004707	MAP kinase activity(GO:0004707)
0.4	0.8	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.4	2.8	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
0.4	2.8	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.4	5.9	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.4	0.4	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.4	27.8	GO:0017124	SH3 domain binding(GO:0017124)
0.4	5.8	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.4	3.1	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.4	2.7	GO:0008158	hedgehog receptor activity(GO:0008158)
0.4	2.7	GO:0017022	myosin binding(GO:0017022)
0.4	11.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.4	8.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.4	2.2	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.4	1.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.4	1.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.4	2.9	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.4	0.7	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.4	1.8	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.4	3.9	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4	1.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.3	1.4	GO:0005497	androgen binding(GO:0005497)
0.3	0.7	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.3	6.2	GO:0004890	GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.3	1.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.3	1.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.3	0.7	GO:0035197	siRNA binding(GO:0035197)
0.3	3.4	GO:0042562	hormone binding(GO:0042562)
0.3	0.7	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.3	2.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.3	2.0	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.3	23.6	GO:0003777	microtubule motor activity(GO:0003777)
0.3	3.5	GO:0005523	tropomyosin binding(GO:0005523)
0.3	3.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.3	3.8	GO:0004065	arylsulfatase activity(GO:0004065)
0.3	1.3	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.3	7.5	GO:0017048	Rho GTPase binding(GO:0017048)
0.3	0.9	GO:0001848	complement binding(GO:0001848)
0.3	2.8	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.3	4.9	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.3	3.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.3	0.6	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.3	1.5	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.3	5.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.3	0.9	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.3	0.9	GO:0019966	interleukin-1 binding(GO:0019966)
0.3	51.6	GO:0003779	actin binding(GO:0003779)
0.3	1.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3	2.6	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.3	1.7	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3	16.2	GO:0004497	monooxygenase activity(GO:0004497)
0.3	18.4	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.3	0.5	GO:0009975	cyclase activity(GO:0009975)
0.3	1.4	GO:0009374	biotin binding(GO:0009374)
0.3	1.9	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.3	4.9	GO:0003774	motor activity(GO:0003774)
0.3	2.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3	1.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.3	51.5	GO:0005096	GTPase activator activity(GO:0005096)
0.3	1.3	GO:0045502	dynein binding(GO:0045502)
0.3	0.8	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3	2.6	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.3	6.2	GO:0005178	integrin binding(GO:0005178)
0.3	1.3	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.3	1.8	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.3	8.3	GO:0008009	chemokine activity(GO:0008009)
0.3	3.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2	0.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.2	1.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2	1.7	GO:0008066	glutamate receptor activity(GO:0008066)
0.2	1.9	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	1.5	GO:0043498	obsolete cell surface binding(GO:0043498)
0.2	106.9	GO:0005509	calcium ion binding(GO:0005509)
0.2	1.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2	1.4	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2	0.7	GO:0015232	heme transporter activity(GO:0015232)
0.2	1.1	GO:0051787	misfolded protein binding(GO:0051787)
0.2	1.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	3.2	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.2	1.3	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.2	0.7	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2	0.9	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2	0.2	GO:0043398	HLH domain binding(GO:0043398)
0.2	3.4	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.2	3.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.2	15.7	GO:0005179	hormone activity(GO:0005179)
0.2	0.2	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2	0.9	GO:0019237	centromeric DNA binding(GO:0019237)
0.2	0.6	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	14.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	0.8	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.2	1.0	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.2	0.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.2	0.6	GO:0046923	ER retention sequence binding(GO:0046923)
0.2	1.4	GO:0042301	phosphate ion binding(GO:0042301)
0.2	0.4	GO:0017127	sterol transporter activity(GO:0015248) cholesterol transporter activity(GO:0017127)
0.2	2.6	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.2	0.6	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2	0.6	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2	0.2	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.2	5.5	GO:0008146	sulfotransferase activity(GO:0008146)
0.2	3.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.2	2.1	GO:0015926	glucosidase activity(GO:0015926)
0.2	0.7	GO:0016594	glycine binding(GO:0016594)
0.2	0.7	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	0.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.2	1.4	GO:0019841	retinol binding(GO:0019841)
0.2	1.2	GO:0004954	prostanoid receptor activity(GO:0004954)
0.2	1.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2	0.3	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.2	1.0	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.2	1.0	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.2	0.6	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2	0.5	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.2	0.9	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.2	0.6	GO:0015057	thrombin receptor activity(GO:0015057)
0.2	3.2	GO:0005496	steroid binding(GO:0005496)
0.2	3.0	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.2	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.4	GO:0034584	piRNA binding(GO:0034584)
0.1	0.7	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1	0.7	GO:0048038	quinone binding(GO:0048038)
0.1	3.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	0.4	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.1	5.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	14.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.3	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	28.0	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.1	1.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.1	0.4	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.7	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	1.0	GO:0008430	selenium binding(GO:0008430)
0.1	0.6	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	3.3	GO:0005262	calcium channel activity(GO:0005262)
0.1	0.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1	0.1	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	0.6	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.1	1.7	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	1.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	3.0	GO:0020037	heme binding(GO:0020037)
0.1	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.3	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	1.6	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.1	0.2	GO:0019863	IgE binding(GO:0019863)
0.1	2.0	GO:0008236	serine-type peptidase activity(GO:0008236)
0.1	0.3	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.1	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.1	0.3	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.1	0.9	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.1	0.2	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	1.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.6	GO:1901681	sulfur compound binding(GO:1901681)
0.1	3.6	GO:0008237	metallopeptidase activity(GO:0008237)
0.1	0.5	GO:0016782	transferase activity, transferring sulfur-containing groups(GO:0016782)
0.1	0.2	GO:0016208	AMP binding(GO:0016208)
0.1	0.6	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.6	GO:0030332	cyclin binding(GO:0030332)
0.1	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.3	GO:0017089	glycolipid transporter activity(GO:0017089)
0.1	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.1	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	21.3	GO:0005198	structural molecule activity(GO:0005198)
0.1	0.7	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1	0.5	GO:0016866	intramolecular transferase activity(GO:0016866)
0.1	8.9	GO:0008289	lipid binding(GO:0008289)
0.1	15.4	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.1	0.1	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.1	1.0	GO:0000149	SNARE binding(GO:0000149)
0.1	0.2	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.1	0.6	GO:0008198	ferrous iron binding(GO:0008198)
0.1	1.1	GO:0019842	vitamin binding(GO:0019842)
0.0	0.0	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.2	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.7	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	1.8	GO:0015293	symporter activity(GO:0015293)
0.0	0.5	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.2	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.6	GO:0000049	tRNA binding(GO:0000049)
0.0	0.1	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.9	GO:0005254	chloride channel activity(GO:0005254)
0.0	0.0	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.0	0.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.4	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.0	GO:0008252	nucleotidase activity(GO:0008252)
0.0	0.1	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	31.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
3.0	44.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
2.1	82.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
1.9	1.9	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
1.5	25.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.4	39.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
1.3	38.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
1.2	15.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.2	30.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.1	24.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
1.1	34.0	NABA COLLAGENS	Genes encoding collagen proteins
1.1	168.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
1.0	4.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.9	31.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.9	11.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.8	12.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.8	20.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.8	32.4	PID BMP PATHWAY	BMP receptor signaling
0.8	4.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.8	6.8	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.8	19.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.7	26.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.7	24.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.7	13.5	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.7	8.9	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.7	22.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.6	20.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.6	7.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.6	95.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.6	17.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.5	6.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.5	121.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5	5.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.5	14.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.5	9.0	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5	3.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.5	2.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.5	15.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.5	12.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.5	4.2	PID ALK1 PATHWAY	ALK1 signaling events
0.5	6.5	ST G ALPHA I PATHWAY	G alpha i Pathway
0.5	12.4	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.4	4.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	0.9	PID REELIN PATHWAY	Reelin signaling pathway
0.4	8.6	PID RHOA PATHWAY	RhoA signaling pathway
0.4	2.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	111.9	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.4	3.8	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.4	0.8	PID S1P S1P3 PATHWAY	S1P3 pathway
0.4	2.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	3.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.3	1.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	10.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	6.1	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.3	6.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.3	4.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.3	4.2	PID AURORA A PATHWAY	Aurora A signaling
0.3	9.7	PID LKB1 PATHWAY	LKB1 signaling events
0.3	3.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.2	0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.2	4.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.2	1.9	ST GA12 PATHWAY	G alpha 12 Pathway
0.2	1.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.2	2.8	PID ARF6 PATHWAY	Arf6 signaling events
0.1	5.3	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.8	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	3.4	PID AURORA B PATHWAY	Aurora B signaling
0.1	1.0	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	0.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	0.4	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.6	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.3	PID FGF PATHWAY	FGF signaling pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	32.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
2.4	2.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.9	21.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.9	50.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
1.9	1.9	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
1.8	34.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
1.5	15.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
1.4	80.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
1.4	17.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
1.4	16.7	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
1.4	1.4	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
1.3	21.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.3	21.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
1.3	14.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
1.3	15.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.3	26.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
1.2	14.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.2	17.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
1.2	11.7	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
1.1	19.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
1.1	23.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
1.0	18.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.9	8.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.9	19.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.9	11.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.9	20.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.9	12.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.9	4.4	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.9	12.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.9	10.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.8	16.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.8	19.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.7	27.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.7	11.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.7	1.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.7	5.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.7	6.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.7	6.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.6	14.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.6	54.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.6	5.0	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.6	8.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.6	28.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.6	17.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.6	9.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.6	6.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.5	14.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.5	11.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.5	11.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.5	3.7	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.5	7.8	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.5	3.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5	28.4	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.5	2.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.5	6.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.5	4.1	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.5	6.0	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.5	6.9	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.5	1.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.5	2.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.5	4.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5	0.9	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.5	46.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.5	1.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.5	5.0	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.4	3.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.4	8.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4	7.8	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.4	6.9	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.4	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.4	2.8	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.4	4.7	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.4	2.0	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.4	19.6	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.4	4.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.4	2.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.4	1.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.4	11.1	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4	1.8	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.3	6.5	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.3	2.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	5.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.3	1.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	3.4	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.3	6.6	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.3	24.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3	1.5	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.3	5.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.3	2.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.3	2.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	4.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.3	2.0	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.3	4.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	6.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	4.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	0.5	REACTOME CELL CELL COMMUNICATION	Genes involved in Cell-Cell communication
0.3	38.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.3	1.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.3	2.6	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.3	1.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	5.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.2	1.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	18.4	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.2	2.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	1.8	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.2	2.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	0.8	REACTOME HIV LIFE CYCLE	Genes involved in HIV Life Cycle
0.2	2.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2	2.0	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	3.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	2.0	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2	0.5	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2	1.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2	6.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	4.9	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	0.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	0.3	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	7.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.0	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	1.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	2.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	3.0	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.1	1.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	0.4	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	0.1	REACTOME OPSINS	Genes involved in Opsins
0.1	1.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.6	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.1	0.5	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	2.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	0.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	2.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.2	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	1.0	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.1	0.6	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	1.0	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	0.5	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.1	1.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.0	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	0.4	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.0	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.1	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME GLYCOSAMINOGLYCAN METABOLISM	Genes involved in Glycosaminoglycan metabolism