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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for SPIB

Z-value: 3.40

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Transcription factors associated with SPIB

Gene Symbol	Gene ID	Gene Info
SPIB Ensembl NCBI GeneCards UniProt	ENSG00000269404.2	Spi-B transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_50922706_50922857	SPIB	566	0.549638	0.25	5.2e-01	Click!
chr19_50922289_50922585	SPIB	222	0.845141	0.17	6.6e-01	Click!

Activity of the SPIB motif across conditions

Conditions sorted by the z-value of the SPIB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_150180608_150181504	2.40	GIMAP7	GTPase, IMAP family member 7	30862	0.13
chr12_57870254_57870608	1.89	ARHGAP9	Rho GTPase activating protein 9	1136	0.26
chr17_3866518_3867344	1.74	ATP2A3	ATPase, Ca++ transporting, ubiquitous	654	0.71
chr7_72408094_72408320	1.72	RP11-313P13.5		12544	0.1
chr15_77287546_77287777	1.70	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	99	0.97
chr19_7413904_7414409	1.65	CTB-133G6.1		308	0.88
chr7_45018291_45018491	1.59	MYO1G	myosin IG	306	0.85
chr9_3398052_3398553	1.56	RFX3	regulatory factor X, 3 (influences HLA class II expression)	2706	0.4
chr1_206732541_206732911	1.51	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	2233	0.27
chr2_103035121_103035519	1.51	IL18RAP	interleukin 18 receptor accessory protein	171	0.93
chr20_56205113_56205264	1.49	ZBP1	Z-DNA binding protein 1	9556	0.23
chr5_126144250_126144473	1.43	LMNB1	lamin B1	31480	0.19
chr10_11212951_11213685	1.40	RP3-323N1.2		21	0.98
chr19_49838375_49839003	1.39	CD37	CD37 molecule	5	0.95
chr7_106505707_106506635	1.38	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	247	0.95
chr7_50351765_50352753	1.37	IKZF1	IKAROS family zinc finger 1 (Ikaros)	3941	0.34
chr1_22402292_22402667	1.36	CDC42-IT1	CDC42 intronic transcript 1 (non-protein coding)	16789	0.13
chr12_109025962_109026141	1.31	SELPLG	selectin P ligand	197	0.91
chr1_160681036_160681588	1.29	CD48	CD48 molecule	281	0.89
chr11_33915442_33916212	1.28	LMO2	LIM domain only 2 (rhombotin-like 1)	1991	0.35
chr15_86098266_86098417	1.26	AKAP13	A kinase (PRKA) anchor protein 13	336	0.89
chr5_171602218_171602369	1.25	STK10	serine/threonine kinase 10	13097	0.19
chr7_50345819_50346403	1.23	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1733	0.5
chr2_10522774_10523051	1.21	HPCAL1	hippocalcin-like 1	37235	0.15
chr1_120935748_120935992	1.18	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	24	0.97
chr1_26316985_26317339	1.16	PAFAH2	platelet-activating factor acetylhydrolase 2, 40kDa	6950	0.1
chrX_131121415_131121857	1.15	ENSG00000265686	.	9237	0.22
chr19_2074395_2074546	1.13	MOB3A	MOB kinase activator 3A	4248	0.13
chr1_66801255_66801864	1.13	PDE4B	phosphodiesterase 4B, cAMP-specific	3687	0.36
chr11_47415900_47416112	1.12	RP11-750H9.5		1185	0.28
chr4_36311811_36312084	1.11	DTHD1	death domain containing 1	26303	0.2
chr2_109238478_109238884	1.10	LIMS1	LIM and senescent cell antigen-like domains 1	959	0.64
chr7_45017320_45017514	1.09	MYO1G	myosin IG	1280	0.35
chr6_116786373_116786594	1.08	RP1-93H18.6		1628	0.26
chr3_151962051_151962251	1.08	MBNL1	muscleblind-like splicing regulator 1	23678	0.2
chr13_41535439_41535590	1.05	ELF1	E74-like factor 1 (ets domain transcription factor)	20904	0.17
chr1_81140230_81140381	1.05	ENSG00000266033	.	345132	0.01
chr2_54789154_54789640	1.03	SPTBN1	spectrin, beta, non-erythrocytic 1	3866	0.23
chr1_154980554_154980872	1.02	ZBTB7B	zinc finger and BTB domain containing 7B	5418	0.08
chr17_30215058_30215300	1.01	UTP6	UTP6, small subunit (SSU) processome component, homolog (yeast)	13605	0.18
chr7_150373424_150373697	0.98	GIMAP2	GTPase, IMAP family member 2	9228	0.17
chr9_132801987_132802138	0.98	FNBP1	formin binding protein 1	3379	0.25
chr9_117689981_117690237	0.97	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	2588	0.39
chr12_54011665_54012567	0.97	ATF7	activating transcription factor 7	7639	0.16
chr14_88471433_88472132	0.97	GPR65	G protein-coupled receptor 65	314	0.88
chr11_93451553_93451767	0.96	ENSG00000199875	.	1109	0.22
chr2_198170219_198170545	0.96	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	3139	0.21
chr1_236031611_236031762	0.95	LYST	lysosomal trafficking regulator	1466	0.35
chr17_1132823_1133042	0.94	ABR	active BCR-related	634	0.72
chr3_157815371_157816030	0.93	SHOX2	short stature homeobox 2	7383	0.25
chr14_20895899_20896050	0.93	KLHL33	kelch-like family member 33	7827	0.08
chr12_99001257_99001439	0.92	ENSG00000221625	.	1696	0.28
chr17_18200351_18200502	0.90	TOP3A	topoisomerase (DNA) III alpha	2495	0.18
chr16_67428890_67429041	0.90	TPPP3	tubulin polymerization-promoting protein family member 3	1527	0.23
chr19_54899574_54899725	0.90	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	17484	0.09
chr5_175960454_175960661	0.89	RNF44	ring finger protein 44	2911	0.17
chr3_151922835_151923340	0.88	MBNL1	muscleblind-like splicing regulator 1	62742	0.13
chr17_4629260_4629411	0.88	MED11	mediator complex subunit 11	5388	0.08
chr3_138505949_138506100	0.87	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	16627	0.26
chrX_47489222_47489415	0.87	CFP	complement factor properdin	24	0.96
chr16_68033325_68033555	0.87	DPEP2	dipeptidase 2	19	0.94
chr3_120136305_120136687	0.87	FSTL1	follistatin-like 1	14352	0.23
chr2_106777289_106777491	0.87	UXS1	UDP-glucuronate decarboxylase 1	309	0.92
chr11_60793991_60794142	0.86	CD6	CD6 molecule	18060	0.14
chr18_11972759_11972910	0.84	IMPA2	inositol(myo)-1(or 4)-monophosphatase 2	8202	0.17
chr11_46694224_46694375	0.84	ATG13	autophagy related 13	8749	0.14
chr4_1725155_1725451	0.83	TACC3	transforming, acidic coiled-coil containing protein 3	466	0.73
chr17_76120714_76120865	0.83	TMC6	transmembrane channel-like 6	1960	0.21
chr11_72122644_72122795	0.83	RP11-7N14.1		959	0.52
chr6_114130917_114131144	0.82	ENSG00000253091	.	28363	0.16
chr2_86081133_86081567	0.81	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	13427	0.17
chr16_89600841_89601123	0.81	ENSG00000252579	.	1020	0.38
chr2_112236952_112237103	0.81	ENSG00000266139	.	158359	0.04
chr17_61778727_61779133	0.81	LIMD2	LIM domain containing 2	398	0.8
chr22_24937848_24937999	0.80	GUCD1	guanylyl cyclase domain containing 1	13134	0.12
chr11_122568313_122568557	0.80	ENSG00000239079	.	28584	0.19
chr1_150738258_150738451	0.79	CTSS	cathepsin S	79	0.96
chr19_3785141_3785292	0.79	MATK	megakaryocyte-associated tyrosine kinase	645	0.55
chr18_11917103_11917288	0.79	MPPE1	metallophosphoesterase 1	7973	0.15
chr3_128951042_128951193	0.79	COPG1	coatomer protein complex, subunit gamma 1	17332	0.14
chr4_6855908_6856059	0.79	TBC1D14	TBC1 domain family, member 14	54986	0.11
chr1_158985417_158985907	0.79	IFI16	interferon, gamma-inducible protein 16	199	0.95
chr9_20377004_20377155	0.78	MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	5388	0.23
chr2_197023764_197023994	0.78	STK17B	serine/threonine kinase 17b	2508	0.29
chr17_29635054_29635205	0.78	EVI2B	ecotropic viral integration site 2B	5973	0.14
chr17_58475814_58475965	0.77	C17orf64	chromosome 17 open reading frame 64	6099	0.22
chr1_52072036_52072187	0.76	OSBPL9	oxysterol binding protein-like 9	10436	0.21
chr15_94779003_94779409	0.76	MCTP2	multiple C2 domains, transmembrane 2	4439	0.37
chr5_131803417_131803568	0.76	ENSG00000202533	.	347	0.82
chr8_8923663_8923814	0.75	ENSG00000239078	.	6288	0.16
chr17_78754518_78754794	0.75	RP11-28G8.1		24776	0.21
chr3_187637243_187637630	0.75	BCL6	B-cell CLL/lymphoma 6	173921	0.03
chr9_123439266_123439417	0.75	MEGF9	multiple EGF-like-domains 9	37271	0.19
chr16_11862664_11862897	0.75	ZC3H7A	zinc finger CCCH-type containing 7A	7596	0.16
chr9_80719235_80719387	0.75	ENSG00000222452	.	61070	0.14
chr1_25255138_25255978	0.74	RUNX3	runt-related transcription factor 3	54	0.98
chr9_140586243_140586394	0.74	EHMT1	euchromatic histone-lysine N-methyltransferase 1	72864	0.07
chr4_154443229_154443447	0.74	KIAA0922	KIAA0922	33710	0.2
chr1_158802859_158803010	0.74	MNDA	myeloid cell nuclear differentiation antigen	1827	0.35
chr11_128593408_128593559	0.73	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	27565	0.16
chr7_50267269_50267784	0.73	IKZF1	IKAROS family zinc finger 1 (Ikaros)	76798	0.1
chr7_2550958_2551215	0.73	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	1077	0.47
chr19_54327118_54327323	0.72	NLRP12	NLR family, pyrin domain containing 12	351	0.63
chr1_63783800_63783951	0.72	RP4-792G4.2		3325	0.22
chr11_33244039_33244190	0.72	ENSG00000200485	.	25931	0.15
chr11_48066553_48066704	0.72	AC103828.1		29221	0.17
chr22_21959101_21959252	0.71	YDJC	YdjC homolog (bacterial)	25149	0.08
chr6_108580201_108580352	0.70	SNX3	sorting nexin 3	1892	0.27
chr10_126329465_126329662	0.70	FAM53B-AS1	FAM53B antisense RNA 1	62631	0.11
chr1_160988813_160989129	0.70	F11R	F11 receptor	1915	0.2
chr6_110011911_110012301	0.69	AK9	adenylate kinase 9	233	0.67
chr16_67580972_67581123	0.69	FAM65A	family with sequence similarity 65, member A	2750	0.12
chr8_102149646_102150020	0.69	ENSG00000202360	.	354	0.91
chr14_78055534_78055772	0.69	SPTLC2	serine palmitoyltransferase, long chain base subunit 2	8011	0.19
chr9_100668829_100668981	0.69	C9orf156	chromosome 9 open reading frame 156	5848	0.17
chr2_43232535_43232725	0.69	ENSG00000207087	.	86002	0.1
chr19_50310817_50311209	0.69	FUZ	fuzzy planar cell polarity protein	883	0.28
chr5_148188537_148188779	0.69	ADRB2	adrenoceptor beta 2, surface	17498	0.25
chr17_76714885_76715036	0.68	CYTH1	cytohesin 1	1853	0.36
chr17_75385878_75386274	0.68	ENSG00000264060	.	7060	0.17
chr21_43639797_43640496	0.68	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	215	0.89
chr6_137543606_137543902	0.68	IFNGR1	interferon gamma receptor 1	3168	0.33
chr15_75069590_75069869	0.68	CSK	c-src tyrosine kinase	4669	0.13
chr5_149060334_149060485	0.68	ENSG00000221043	.	15113	0.15
chr1_198609469_198609717	0.67	PTPRC	protein tyrosine phosphatase, receptor type, C	1301	0.54
chr19_10380429_10381098	0.67	ICAM1	intercellular adhesion molecule 1	748	0.39
chr9_101899616_101899767	0.67	ENSG00000252942	.	8557	0.19
chr19_4559724_4559875	0.67	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	21	0.96
chr9_212362_212513	0.66	DOCK8	dedicator of cytokinesis 8	2428	0.26
chr2_87770167_87770354	0.66	RP11-1399P15.1		7293	0.31
chr2_54221778_54222027	0.66	ACYP2	acylphosphatase 2, muscle type	23657	0.18
chr15_47796923_47797164	0.65	RP11-142J21.2		20323	0.2
chr16_50622993_50623235	0.65	RP11-401P9.6		24481	0.14
chr7_26333293_26333815	0.65	SNX10	sorting nexin 10	880	0.67
chr13_100072782_100072933	0.65	ENSG00000266207	.	32866	0.16
chr14_71108988_71109591	0.65	TTC9	tetratricopeptide repeat domain 9	785	0.67
chr17_38738771_38738954	0.64	CCR7	chemokine (C-C motif) receptor 7	17138	0.15
chr16_89830973_89831469	0.64	FANCA	Fanconi anemia, complementation group A	19751	0.11
chr2_68917393_68917544	0.64	ARHGAP25	Rho GTPase activating protein 25	20166	0.22
chr10_126429198_126429868	0.64	FAM53B	family with sequence similarity 53, member B	2006	0.29
chr19_42851358_42851509	0.64	MEGF8	multiple EGF-like-domains 8	13689	0.1
chr14_90148063_90148287	0.64	ENSG00000200312	.	30680	0.14
chr4_159460198_159460349	0.63	RXFP1	relaxin/insulin-like family peptide receptor 1	17144	0.21
chr17_17654361_17654512	0.63	RAI1-AS1	RAI1 antisense RNA 1	19699	0.13
chr10_30782904_30783098	0.63	MAP3K8	mitogen-activated protein kinase kinase kinase 8	55250	0.12
chr2_198064690_198065196	0.63	ANKRD44	ankyrin repeat domain 44	2181	0.29
chr9_33226897_33227141	0.63	SPINK4	serine peptidase inhibitor, Kazal type 4	6042	0.16
chr10_99168347_99168498	0.63	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	7295	0.1
chr2_68962051_68962936	0.63	ARHGAP25	Rho GTPase activating protein 25	479	0.86
chr22_39148225_39148574	0.63	SUN2	Sad1 and UNC84 domain containing 2	2080	0.14
chr2_182323559_182323800	0.63	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	1524	0.55
chr16_2610123_2610274	0.62	RP11-20I23.13		4137	0.07
chr6_116950636_116950920	0.62	RSPH4A	radial spoke head 4 homolog A (Chlamydomonas)	12991	0.16
chr5_149790034_149790185	0.62	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	2186	0.28
chr7_72738103_72738636	0.62	TRIM50	tripartite motif containing 50	1206	0.36
chr5_118668748_118668899	0.62	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	47	0.98
chr17_43305439_43305590	0.62	CTD-2020K17.1		5925	0.1
chr20_55059093_55059344	0.61	ENSG00000238294	.	8519	0.13
chr8_41907411_41908748	0.61	KAT6A	K(lysine) acetyltransferase 6A	1426	0.43
chr2_43460702_43460865	0.61	AC010883.5		4071	0.27
chr19_14550932_14551083	0.61	PKN1	protein kinase N1	65	0.95
chr15_83513837_83513988	0.61	HOMER2	homer homolog 2 (Drosophila)	4567	0.18
chr12_120729183_120729407	0.61	ENSG00000202538	.	411	0.71
chr1_150997007_150997158	0.61	PRUNE	prune exopolyphosphatase	136	0.89
chr15_86233707_86233858	0.61	RP11-815J21.1		10558	0.11
chr6_25039479_25039685	0.61	RP3-425P12.5		2485	0.24
chr10_71720102_71720253	0.61	COL13A1	collagen, type XIII, alpha 1	29968	0.2
chr7_5481756_5481907	0.60	TNRC18	trinucleotide repeat containing 18	16786	0.12
chr4_185373022_185373173	0.60	ENSG00000251878	.	19977	0.17
chr12_8101164_8101417	0.59	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	12419	0.15
chr17_75424510_75424661	0.59	SEPT9	septin 9	1547	0.34
chr10_99115363_99115514	0.59	FRAT2	frequently rearranged in advanced T-cell lymphomas 2	20980	0.1
chr1_81137188_81137522	0.59	ENSG00000266033	.	342182	0.01
chr4_73951905_73952308	0.59	COX18	COX18 cytochrome C oxidase assembly factor	16648	0.24
chr2_85727465_85727616	0.59	ENSG00000266577	.	32209	0.08
chr11_118085317_118085565	0.59	AMICA1	adhesion molecule, interacts with CXADR antigen 1	165	0.94
chr12_6753395_6753549	0.59	ACRBP	acrosin binding protein	3087	0.11
chr8_17760523_17760674	0.59	FGL1	fibrinogen-like 1	7276	0.19
chr1_161038546_161039545	0.58	ARHGAP30	Rho GTPase activating protein 30	411	0.65
chr12_15110215_15110471	0.58	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	3857	0.2
chr7_139560006_139560157	0.58	TBXAS1	thromboxane A synthase 1 (platelet)	30971	0.21
chr5_76527145_76527311	0.58	PDE8B	phosphodiesterase 8B	17459	0.23
chr7_75056891_75057059	0.58	NSUN5P1	NOP2/Sun domain family, member 5 pseudogene 1	11793	0.11
chr11_72452586_72452737	0.58	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	10787	0.12
chr6_14922002_14922153	0.58	ENSG00000242989	.	191122	0.03
chr1_151028526_151028866	0.58	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	1538	0.19
chr22_39147860_39148011	0.58	SUN2	Sad1 and UNC84 domain containing 2	1616	0.18
chr11_5713127_5713492	0.57	TRIM22	tripartite motif containing 22	1052	0.38
chr7_100147933_100148164	0.57	AGFG2	ArfGAP with FG repeats 2	5242	0.09
chr4_100768580_100768801	0.57	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	30687	0.17
chr12_15113710_15114247	0.57	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	222	0.92
chr12_47600587_47601314	0.57	PCED1B	PC-esterase domain containing 1B	9102	0.22
chr17_16171601_16171752	0.57	ENSG00000221355	.	13652	0.16
chr5_169785299_169785450	0.57	KCNIP1	Kv channel interacting protein 1	4883	0.21
chr17_44217083_44217234	0.57	ENSG00000252698	.	12396	0.18
chr15_101715559_101715845	0.57	CHSY1	chondroitin sulfate synthase 1	76435	0.08
chr11_77121542_77121693	0.57	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	1332	0.52
chr7_72706172_72706353	0.57	GTF2IRD2P1	GTF2I repeat domain containing 2 pseudogene 1	12119	0.13
chr12_69742009_69742310	0.57	LYZ	lysozyme	5	0.97
chr22_37270577_37270728	0.57	NCF4	neutrophil cytosolic factor 4, 40kDa	2473	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.3	0.9	GO:0010447	response to acidic pH(GO:0010447)
0.3	1.3	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.2	0.8	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.5	GO:0035455	response to interferon-alpha(GO:0035455)
0.2	0.7	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2	0.7	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.5	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.2	0.6	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.2	0.5	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.7	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.7	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	2.5	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.4	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.4	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.8	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.5	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.8	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.5	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1	0.5	GO:0046645	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1	0.4	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.4	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.9	GO:0015671	oxygen transport(GO:0015671)
0.1	1.3	GO:0030224	monocyte differentiation(GO:0030224)
0.1	0.5	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.2	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1	0.9	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	1.4	GO:0002920	regulation of humoral immune response(GO:0002920)
0.1	0.4	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0043373	T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1	1.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.4	GO:0022417	protein maturation by protein folding(GO:0022417)
0.1	0.2	GO:0003032	detection of oxygen(GO:0003032)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	1.6	GO:0045576	mast cell activation(GO:0045576)
0.1	0.4	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.2	GO:0051138	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1	0.5	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.7	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.1	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:0015851	nucleobase transport(GO:0015851)
0.1	0.2	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.1	GO:0002363	B cell lineage commitment(GO:0002326) alpha-beta T cell lineage commitment(GO:0002363)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.1	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1	0.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.1	GO:0002125	maternal aggressive behavior(GO:0002125)
0.1	0.5	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.8	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.3	GO:0007341	penetration of zona pellucida(GO:0007341)
0.1	0.3	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.2	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.2	GO:0001787	natural killer cell proliferation(GO:0001787)
0.1	0.4	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.2	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.1	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.2	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.1	0.4	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.1	GO:0060789	hair follicle placode formation(GO:0060789)
0.1	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	0.2	GO:0006667	sphinganine metabolic process(GO:0006667)
0.1	0.1	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1	0.1	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.1	GO:0045357	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.2	GO:0033622	integrin activation(GO:0033622)
0.1	0.8	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	0.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1	0.5	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1	0.2	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.1	0.2	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.2	GO:0070339	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.1	0.2	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.1	0.3	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.1	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.1	0.2	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.1	0.2	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1	0.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1	0.7	GO:0045730	respiratory burst(GO:0045730)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.9	GO:0007032	endosome organization(GO:0007032)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.3	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.5	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.2	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.2	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.7	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.3	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	1.0	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.8	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.4	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.2	GO:0007097	nuclear migration(GO:0007097)
0.0	2.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.2	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.9	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0010758	regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.3	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.4	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.3	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.3	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.3	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.5	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0032329	serine transport(GO:0032329)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.2	GO:0036230	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	1.4	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.2	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.3	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.8	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0022011	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.2	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.0	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0032782	canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0	0.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.4	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) negative regulation of glial cell proliferation(GO:0060253)
0.0	0.2	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.2	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.8	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.2	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	2.0	GO:0006754	ATP biosynthetic process(GO:0006754)
0.0	0.1	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0002740	negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.1	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.2	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.5	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.3	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.2	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.2	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.1	GO:0051900	regulation of mitochondrial depolarization(GO:0051900)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	1.6	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.3	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.2	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.2	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.2	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.3	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.7	GO:0007569	cell aging(GO:0007569)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0032365	intracellular lipid transport(GO:0032365)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.4	GO:0030218	erythrocyte differentiation(GO:0030218)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.0	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.3	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.0	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.0	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.0	GO:1903319	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0	0.0	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.2	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.6	GO:0007033	vacuole organization(GO:0007033)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.4	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.0	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.0	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0050773	regulation of dendrite development(GO:0050773)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0001554	luteolysis(GO:0001554)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.0	GO:0010829	negative regulation of glucose transport(GO:0010829)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.4	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.0	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.3	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.4	GO:1901264	carbohydrate derivative transport(GO:1901264)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.3	GO:0007041	lysosomal transport(GO:0007041)
0.0	0.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.3	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.6	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.1	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.4	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.3	GO:0030837	negative regulation of actin filament polymerization(GO:0030837)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.0	GO:1904377	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0015893	drug transport(GO:0015893)
0.0	0.1	GO:0006228	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	1.5	GO:0097190	apoptotic signaling pathway(GO:0097190)
0.0	0.5	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0042269	regulation of natural killer cell mediated immunity(GO:0002715) regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.2	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0010165	response to X-ray(GO:0010165)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0045006	DNA deamination(GO:0045006)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.3	GO:0051017	actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0048741	skeletal muscle fiber development(GO:0048741)
0.0	0.1	GO:0098657	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.0	GO:0060405	regulation of penile erection(GO:0060405)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0	0.2	GO:0070206	protein trimerization(GO:0070206)
0.0	0.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.2	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	1.3	GO:0043087	regulation of GTPase activity(GO:0043087)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.0	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.0	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:1902622	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.0	GO:0032479	regulation of type I interferon production(GO:0032479)
0.0	0.2	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.5	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.0	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.0	GO:0048535	lymph node development(GO:0048535)
0.0	0.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.0	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.0	GO:0060192	negative regulation of lipase activity(GO:0060192)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0042401	polyamine biosynthetic process(GO:0006596) cellular biogenic amine biosynthetic process(GO:0042401)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.5	GO:0072413	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.1	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011) UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.0	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0043101	purine-containing compound salvage(GO:0043101)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.9	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	1.4	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.2	2.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	0.5	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.4	GO:0005638	lamin filament(GO:0005638)
0.1	0.4	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.1	GO:0070938	contractile ring(GO:0070938)
0.1	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.3	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:0030312	external encapsulating structure(GO:0030312)
0.1	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.4	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.1	0.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.3	GO:0005827	polar microtubule(GO:0005827)
0.1	0.5	GO:0000145	exocyst(GO:0000145)
0.1	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.2	GO:0032009	early phagosome(GO:0032009)
0.1	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	0.3	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.6	GO:0001772	immunological synapse(GO:0001772)
0.1	0.3	GO:0071817	MMXD complex(GO:0071817)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.2	GO:0001740	Barr body(GO:0001740)
0.1	0.5	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.4	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.7	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	2.0	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.5	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	1.0	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.6	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	1.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	1.2	GO:0031901	early endosome membrane(GO:0031901)
0.0	1.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	1.3	GO:0016605	PML body(GO:0016605)
0.0	1.1	GO:0055037	recycling endosome(GO:0055037)
0.0	0.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.3	GO:0042641	actomyosin(GO:0042641)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	1.3	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	2.4	GO:0016607	nuclear speck(GO:0016607)
0.0	0.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0005771	multivesicular body(GO:0005771)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	1.5	GO:0010008	endosome membrane(GO:0010008)
0.0	0.5	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.0	GO:0038201	TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	1.0	GO:0005769	early endosome(GO:0005769)
0.0	0.4	GO:0043195	terminal bouton(GO:0043195)
0.0	0.0	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.6	GO:0030496	midbody(GO:0030496)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.5	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.3	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.0	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.0	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.7	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	1.1	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.7	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	2.4	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.9	GO:0005925	focal adhesion(GO:0005925)
0.0	0.0	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.2	GO:0005657	replication fork(GO:0005657)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	1.3	GO:0000785	chromatin(GO:0000785)
0.0	0.0	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.4	2.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4	1.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	0.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	1.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.2	1.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.2	0.6	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.4	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.4	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.4	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.4	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.4	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.3	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	1.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.1	0.9	GO:0019864	IgG binding(GO:0019864)
0.1	1.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.4	GO:0005534	galactose binding(GO:0005534)
0.1	0.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.4	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.5	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.4	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.3	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.2	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1	0.3	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	1.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.4	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	2.4	GO:0003823	antigen binding(GO:0003823)
0.1	0.5	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.9	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.6	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.8	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.4	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.1	0.4	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.4	GO:0005521	lamin binding(GO:0005521)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.4	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0035197	siRNA binding(GO:0035197)
0.1	0.8	GO:0019534	toxin transporter activity(GO:0019534)
0.1	0.2	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.2	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.3	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0015605	organophosphate ester transmembrane transporter activity(GO:0015605)
0.0	0.4	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.8	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.6	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	1.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	2.1	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.6	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.6	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.3	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.4	GO:0046970	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.3	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.8	GO:0036459	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.2	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	1.0	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.3	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.3	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.3	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.5	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	1.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.4	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.5	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.4	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.5	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.2	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.5	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.2	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	1.3	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	1.9	GO:0003774	motor activity(GO:0003774)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.2	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.0	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.0	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.2	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.0	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.5	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.0	0.5	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.3	GO:0019825	oxygen binding(GO:0019825)
0.0	0.0	GO:0070513	death domain binding(GO:0070513)
0.0	0.3	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.4	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.0	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.2	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	1.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	1.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	1.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	0.8	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	3.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	2.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	2.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	0.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	1.0	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.7	PID EPO PATHWAY	EPO signaling pathway
0.0	0.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.0	ST ADRENERGIC	Adrenergic Pathway
0.0	0.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.3	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.7	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.3	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.6	PID ARF6 PATHWAY	Arf6 signaling events
0.0	1.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.8	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.9	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.0	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	1.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	3.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	1.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	3.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.2	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	0.7	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.0	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.0	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	1.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.8	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.3	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.2	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.7	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.0	REACTOME G1 S TRANSITION	Genes involved in G1/S Transition
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.4	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+

Results for SPIB

Z-value: 3.40

Motif logo

Transcription factors associated with SPIB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the SPIB motif across conditions

Conditions sorted by the z-value of the SPIB motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: