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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SPIB

Z-value: 3.40

Motif logo

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Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
ENSG00000269404.2 SPIB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
SPIBchr19_50922706_509228575660.5496380.255.2e-01Click!
SPIBchr19_50922289_509225852220.8451410.176.6e-01Click!

Activity of the SPIB motif across conditions

Conditions sorted by the z-value of the SPIB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_150180608_150181504 2.40 GIMAP7
GTPase, IMAP family member 7
30862
0.13
chr12_57870254_57870608 1.89 ARHGAP9
Rho GTPase activating protein 9
1136
0.26
chr17_3866518_3867344 1.74 ATP2A3
ATPase, Ca++ transporting, ubiquitous
654
0.71
chr7_72408094_72408320 1.72 RP11-313P13.5

12544
0.1
chr15_77287546_77287777 1.70 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
99
0.97
chr19_7413904_7414409 1.65 CTB-133G6.1

308
0.88
chr7_45018291_45018491 1.59 MYO1G
myosin IG
306
0.85
chr9_3398052_3398553 1.56 RFX3
regulatory factor X, 3 (influences HLA class II expression)
2706
0.4
chr1_206732541_206732911 1.51 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
2233
0.27
chr2_103035121_103035519 1.51 IL18RAP
interleukin 18 receptor accessory protein
171
0.93
chr20_56205113_56205264 1.49 ZBP1
Z-DNA binding protein 1
9556
0.23
chr5_126144250_126144473 1.43 LMNB1
lamin B1
31480
0.19
chr10_11212951_11213685 1.40 RP3-323N1.2

21
0.98
chr19_49838375_49839003 1.39 CD37
CD37 molecule
5
0.95
chr7_106505707_106506635 1.38 PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
247
0.95
chr7_50351765_50352753 1.37 IKZF1
IKAROS family zinc finger 1 (Ikaros)
3941
0.34
chr1_22402292_22402667 1.36 CDC42-IT1
CDC42 intronic transcript 1 (non-protein coding)
16789
0.13
chr12_109025962_109026141 1.31 SELPLG
selectin P ligand
197
0.91
chr1_160681036_160681588 1.29 CD48
CD48 molecule
281
0.89
chr11_33915442_33916212 1.28 LMO2
LIM domain only 2 (rhombotin-like 1)
1991
0.35
chr15_86098266_86098417 1.26 AKAP13
A kinase (PRKA) anchor protein 13
336
0.89
chr5_171602218_171602369 1.25 STK10
serine/threonine kinase 10
13097
0.19
chr7_50345819_50346403 1.23 IKZF1
IKAROS family zinc finger 1 (Ikaros)
1733
0.5
chr2_10522774_10523051 1.21 HPCAL1
hippocalcin-like 1
37235
0.15
chr1_120935748_120935992 1.18 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
24
0.97
chr1_26316985_26317339 1.16 PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
6950
0.1
chrX_131121415_131121857 1.15 ENSG00000265686
.
9237
0.22
chr19_2074395_2074546 1.13 MOB3A
MOB kinase activator 3A
4248
0.13
chr1_66801255_66801864 1.13 PDE4B
phosphodiesterase 4B, cAMP-specific
3687
0.36
chr11_47415900_47416112 1.12 RP11-750H9.5

1185
0.28
chr4_36311811_36312084 1.11 DTHD1
death domain containing 1
26303
0.2
chr2_109238478_109238884 1.10 LIMS1
LIM and senescent cell antigen-like domains 1
959
0.64
chr7_45017320_45017514 1.09 MYO1G
myosin IG
1280
0.35
chr6_116786373_116786594 1.08 RP1-93H18.6

1628
0.26
chr3_151962051_151962251 1.08 MBNL1
muscleblind-like splicing regulator 1
23678
0.2
chr13_41535439_41535590 1.05 ELF1
E74-like factor 1 (ets domain transcription factor)
20904
0.17
chr1_81140230_81140381 1.05 ENSG00000266033
.
345132
0.01
chr2_54789154_54789640 1.03 SPTBN1
spectrin, beta, non-erythrocytic 1
3866
0.23
chr1_154980554_154980872 1.02 ZBTB7B
zinc finger and BTB domain containing 7B
5418
0.08
chr17_30215058_30215300 1.01 UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
13605
0.18
chr7_150373424_150373697 0.98 GIMAP2
GTPase, IMAP family member 2
9228
0.17
chr9_132801987_132802138 0.98 FNBP1
formin binding protein 1
3379
0.25
chr9_117689981_117690237 0.97 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
2588
0.39
chr12_54011665_54012567 0.97 ATF7
activating transcription factor 7
7639
0.16
chr14_88471433_88472132 0.97 GPR65
G protein-coupled receptor 65
314
0.88
chr11_93451553_93451767 0.96 ENSG00000199875
.
1109
0.22
chr2_198170219_198170545 0.96 ANKRD44-IT1
ANKRD44 intronic transcript 1 (non-protein coding)
3139
0.21
chr1_236031611_236031762 0.95 LYST
lysosomal trafficking regulator
1466
0.35
chr17_1132823_1133042 0.94 ABR
active BCR-related
634
0.72
chr3_157815371_157816030 0.93 SHOX2
short stature homeobox 2
7383
0.25
chr14_20895899_20896050 0.93 KLHL33
kelch-like family member 33
7827
0.08
chr12_99001257_99001439 0.92 ENSG00000221625
.
1696
0.28
chr17_18200351_18200502 0.90 TOP3A
topoisomerase (DNA) III alpha
2495
0.18
chr16_67428890_67429041 0.90 TPPP3
tubulin polymerization-promoting protein family member 3
1527
0.23
chr19_54899574_54899725 0.90 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
17484
0.09
chr5_175960454_175960661 0.89 RNF44
ring finger protein 44
2911
0.17
chr3_151922835_151923340 0.88 MBNL1
muscleblind-like splicing regulator 1
62742
0.13
chr17_4629260_4629411 0.88 MED11
mediator complex subunit 11
5388
0.08
chr3_138505949_138506100 0.87 PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
16627
0.26
chrX_47489222_47489415 0.87 CFP
complement factor properdin
24
0.96
chr16_68033325_68033555 0.87 DPEP2
dipeptidase 2
19
0.94
chr3_120136305_120136687 0.87 FSTL1
follistatin-like 1
14352
0.23
chr2_106777289_106777491 0.87 UXS1
UDP-glucuronate decarboxylase 1
309
0.92
chr11_60793991_60794142 0.86 CD6
CD6 molecule
18060
0.14
chr18_11972759_11972910 0.84 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
8202
0.17
chr11_46694224_46694375 0.84 ATG13
autophagy related 13
8749
0.14
chr4_1725155_1725451 0.83 TACC3
transforming, acidic coiled-coil containing protein 3
466
0.73
chr17_76120714_76120865 0.83 TMC6
transmembrane channel-like 6
1960
0.21
chr11_72122644_72122795 0.83 RP11-7N14.1

959
0.52
chr6_114130917_114131144 0.82 ENSG00000253091
.
28363
0.16
chr2_86081133_86081567 0.81 ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
13427
0.17
chr16_89600841_89601123 0.81 ENSG00000252579
.
1020
0.38
chr2_112236952_112237103 0.81 ENSG00000266139
.
158359
0.04
chr17_61778727_61779133 0.81 LIMD2
LIM domain containing 2
398
0.8
chr22_24937848_24937999 0.80 GUCD1
guanylyl cyclase domain containing 1
13134
0.12
chr11_122568313_122568557 0.80 ENSG00000239079
.
28584
0.19
chr1_150738258_150738451 0.79 CTSS
cathepsin S
79
0.96
chr19_3785141_3785292 0.79 MATK
megakaryocyte-associated tyrosine kinase
645
0.55
chr18_11917103_11917288 0.79 MPPE1
metallophosphoesterase 1
7973
0.15
chr3_128951042_128951193 0.79 COPG1
coatomer protein complex, subunit gamma 1
17332
0.14
chr4_6855908_6856059 0.79 TBC1D14
TBC1 domain family, member 14
54986
0.11
chr1_158985417_158985907 0.79 IFI16
interferon, gamma-inducible protein 16
199
0.95
chr9_20377004_20377155 0.78 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
5388
0.23
chr2_197023764_197023994 0.78 STK17B
serine/threonine kinase 17b
2508
0.29
chr17_29635054_29635205 0.78 EVI2B
ecotropic viral integration site 2B
5973
0.14
chr17_58475814_58475965 0.77 C17orf64
chromosome 17 open reading frame 64
6099
0.22
chr1_52072036_52072187 0.76 OSBPL9
oxysterol binding protein-like 9
10436
0.21
chr15_94779003_94779409 0.76 MCTP2
multiple C2 domains, transmembrane 2
4439
0.37
chr5_131803417_131803568 0.76 ENSG00000202533
.
347
0.82
chr8_8923663_8923814 0.75 ENSG00000239078
.
6288
0.16
chr17_78754518_78754794 0.75 RP11-28G8.1

24776
0.21
chr3_187637243_187637630 0.75 BCL6
B-cell CLL/lymphoma 6
173921
0.03
chr9_123439266_123439417 0.75 MEGF9
multiple EGF-like-domains 9
37271
0.19
chr16_11862664_11862897 0.75 ZC3H7A
zinc finger CCCH-type containing 7A
7596
0.16
chr9_80719235_80719387 0.75 ENSG00000222452
.
61070
0.14
chr1_25255138_25255978 0.74 RUNX3
runt-related transcription factor 3
54
0.98
chr9_140586243_140586394 0.74 EHMT1
euchromatic histone-lysine N-methyltransferase 1
72864
0.07
chr4_154443229_154443447 0.74 KIAA0922
KIAA0922
33710
0.2
chr1_158802859_158803010 0.74 MNDA
myeloid cell nuclear differentiation antigen
1827
0.35
chr11_128593408_128593559 0.73 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
27565
0.16
chr7_50267269_50267784 0.73 IKZF1
IKAROS family zinc finger 1 (Ikaros)
76798
0.1
chr7_2550958_2551215 0.73 LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
1077
0.47
chr19_54327118_54327323 0.72 NLRP12
NLR family, pyrin domain containing 12
351
0.63
chr1_63783800_63783951 0.72 RP4-792G4.2

3325
0.22
chr11_33244039_33244190 0.72 ENSG00000200485
.
25931
0.15
chr11_48066553_48066704 0.72 AC103828.1

29221
0.17
chr22_21959101_21959252 0.71 YDJC
YdjC homolog (bacterial)
25149
0.08
chr6_108580201_108580352 0.70 SNX3
sorting nexin 3
1892
0.27
chr10_126329465_126329662 0.70 FAM53B-AS1
FAM53B antisense RNA 1
62631
0.11
chr1_160988813_160989129 0.70 F11R
F11 receptor
1915
0.2
chr6_110011911_110012301 0.69 AK9
adenylate kinase 9
233
0.67
chr16_67580972_67581123 0.69 FAM65A
family with sequence similarity 65, member A
2750
0.12
chr8_102149646_102150020 0.69 ENSG00000202360
.
354
0.91
chr14_78055534_78055772 0.69 SPTLC2
serine palmitoyltransferase, long chain base subunit 2
8011
0.19
chr9_100668829_100668981 0.69 C9orf156
chromosome 9 open reading frame 156
5848
0.17
chr2_43232535_43232725 0.69 ENSG00000207087
.
86002
0.1
chr19_50310817_50311209 0.69 FUZ
fuzzy planar cell polarity protein
883
0.28
chr5_148188537_148188779 0.69 ADRB2
adrenoceptor beta 2, surface
17498
0.25
chr17_76714885_76715036 0.68 CYTH1
cytohesin 1
1853
0.36
chr17_75385878_75386274 0.68 ENSG00000264060
.
7060
0.17
chr21_43639797_43640496 0.68 ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
215
0.89
chr6_137543606_137543902 0.68 IFNGR1
interferon gamma receptor 1
3168
0.33
chr15_75069590_75069869 0.68 CSK
c-src tyrosine kinase
4669
0.13
chr5_149060334_149060485 0.68 ENSG00000221043
.
15113
0.15
chr1_198609469_198609717 0.67 PTPRC
protein tyrosine phosphatase, receptor type, C
1301
0.54
chr19_10380429_10381098 0.67 ICAM1
intercellular adhesion molecule 1
748
0.39
chr9_101899616_101899767 0.67 ENSG00000252942
.
8557
0.19
chr19_4559724_4559875 0.67 SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
21
0.96
chr9_212362_212513 0.66 DOCK8
dedicator of cytokinesis 8
2428
0.26
chr2_87770167_87770354 0.66 RP11-1399P15.1

7293
0.31
chr2_54221778_54222027 0.66 ACYP2
acylphosphatase 2, muscle type
23657
0.18
chr15_47796923_47797164 0.65 RP11-142J21.2

20323
0.2
chr16_50622993_50623235 0.65 RP11-401P9.6

24481
0.14
chr7_26333293_26333815 0.65 SNX10
sorting nexin 10
880
0.67
chr13_100072782_100072933 0.65 ENSG00000266207
.
32866
0.16
chr14_71108988_71109591 0.65 TTC9
tetratricopeptide repeat domain 9
785
0.67
chr17_38738771_38738954 0.64 CCR7
chemokine (C-C motif) receptor 7
17138
0.15
chr16_89830973_89831469 0.64 FANCA
Fanconi anemia, complementation group A
19751
0.11
chr2_68917393_68917544 0.64 ARHGAP25
Rho GTPase activating protein 25
20166
0.22
chr10_126429198_126429868 0.64 FAM53B
family with sequence similarity 53, member B
2006
0.29
chr19_42851358_42851509 0.64 MEGF8
multiple EGF-like-domains 8
13689
0.1
chr14_90148063_90148287 0.64 ENSG00000200312
.
30680
0.14
chr4_159460198_159460349 0.63 RXFP1
relaxin/insulin-like family peptide receptor 1
17144
0.21
chr17_17654361_17654512 0.63 RAI1-AS1
RAI1 antisense RNA 1
19699
0.13
chr10_30782904_30783098 0.63 MAP3K8
mitogen-activated protein kinase kinase kinase 8
55250
0.12
chr2_198064690_198065196 0.63 ANKRD44
ankyrin repeat domain 44
2181
0.29
chr9_33226897_33227141 0.63 SPINK4
serine peptidase inhibitor, Kazal type 4
6042
0.16
chr10_99168347_99168498 0.63 RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
7295
0.1
chr2_68962051_68962936 0.63 ARHGAP25
Rho GTPase activating protein 25
479
0.86
chr22_39148225_39148574 0.63 SUN2
Sad1 and UNC84 domain containing 2
2080
0.14
chr2_182323559_182323800 0.63 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
1524
0.55
chr16_2610123_2610274 0.62 RP11-20I23.13

4137
0.07
chr6_116950636_116950920 0.62 RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
12991
0.16
chr5_149790034_149790185 0.62 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
2186
0.28
chr7_72738103_72738636 0.62 TRIM50
tripartite motif containing 50
1206
0.36
chr5_118668748_118668899 0.62 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
47
0.98
chr17_43305439_43305590 0.62 CTD-2020K17.1

5925
0.1
chr20_55059093_55059344 0.61 ENSG00000238294
.
8519
0.13
chr8_41907411_41908748 0.61 KAT6A
K(lysine) acetyltransferase 6A
1426
0.43
chr2_43460702_43460865 0.61 AC010883.5

4071
0.27
chr19_14550932_14551083 0.61 PKN1
protein kinase N1
65
0.95
chr15_83513837_83513988 0.61 HOMER2
homer homolog 2 (Drosophila)
4567
0.18
chr12_120729183_120729407 0.61 ENSG00000202538
.
411
0.71
chr1_150997007_150997158 0.61 PRUNE
prune exopolyphosphatase
136
0.89
chr15_86233707_86233858 0.61 RP11-815J21.1

10558
0.11
chr6_25039479_25039685 0.61 RP3-425P12.5

2485
0.24
chr10_71720102_71720253 0.61 COL13A1
collagen, type XIII, alpha 1
29968
0.2
chr7_5481756_5481907 0.60 TNRC18
trinucleotide repeat containing 18
16786
0.12
chr4_185373022_185373173 0.60 ENSG00000251878
.
19977
0.17
chr12_8101164_8101417 0.59 SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
12419
0.15
chr17_75424510_75424661 0.59 SEPT9
septin 9
1547
0.34
chr10_99115363_99115514 0.59 FRAT2
frequently rearranged in advanced T-cell lymphomas 2
20980
0.1
chr1_81137188_81137522 0.59 ENSG00000266033
.
342182
0.01
chr4_73951905_73952308 0.59 COX18
COX18 cytochrome C oxidase assembly factor
16648
0.24
chr2_85727465_85727616 0.59 ENSG00000266577
.
32209
0.08
chr11_118085317_118085565 0.59 AMICA1
adhesion molecule, interacts with CXADR antigen 1
165
0.94
chr12_6753395_6753549 0.59 ACRBP
acrosin binding protein
3087
0.11
chr8_17760523_17760674 0.59 FGL1
fibrinogen-like 1
7276
0.19
chr1_161038546_161039545 0.58 ARHGAP30
Rho GTPase activating protein 30
411
0.65
chr12_15110215_15110471 0.58 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
3857
0.2
chr7_139560006_139560157 0.58 TBXAS1
thromboxane A synthase 1 (platelet)
30971
0.21
chr5_76527145_76527311 0.58 PDE8B
phosphodiesterase 8B
17459
0.23
chr7_75056891_75057059 0.58 NSUN5P1
NOP2/Sun domain family, member 5 pseudogene 1
11793
0.11
chr11_72452586_72452737 0.58 ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
10787
0.12
chr6_14922002_14922153 0.58 ENSG00000242989
.
191122
0.03
chr1_151028526_151028866 0.58 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
1538
0.19
chr22_39147860_39148011 0.58 SUN2
Sad1 and UNC84 domain containing 2
1616
0.18
chr11_5713127_5713492 0.57 TRIM22
tripartite motif containing 22
1052
0.38
chr7_100147933_100148164 0.57 AGFG2
ArfGAP with FG repeats 2
5242
0.09
chr4_100768580_100768801 0.57 DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
30687
0.17
chr12_15113710_15114247 0.57 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
222
0.92
chr12_47600587_47601314 0.57 PCED1B
PC-esterase domain containing 1B
9102
0.22
chr17_16171601_16171752 0.57 ENSG00000221355
.
13652
0.16
chr5_169785299_169785450 0.57 KCNIP1
Kv channel interacting protein 1
4883
0.21
chr17_44217083_44217234 0.57 ENSG00000252698
.
12396
0.18
chr15_101715559_101715845 0.57 CHSY1
chondroitin sulfate synthase 1
76435
0.08
chr11_77121542_77121693 0.57 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
1332
0.52
chr7_72706172_72706353 0.57 GTF2IRD2P1
GTF2I repeat domain containing 2 pseudogene 1
12119
0.13
chr12_69742009_69742310 0.57 LYZ
lysozyme
5
0.97
chr22_37270577_37270728 0.57 NCF4
neutrophil cytosolic factor 4, 40kDa
2473
0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of SPIB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 0.9 GO:0010447 response to acidic pH(GO:0010447)
0.3 1.3 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.2 0.8 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2 0.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.2 0.7 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.5 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.2 0.6 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.2 0.5 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.7 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 2.5 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.4 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.5 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.5 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.5 GO:0046645 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.4 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.4 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.9 GO:0015671 oxygen transport(GO:0015671)
0.1 1.3 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.5 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 1.4 GO:0002920 regulation of humoral immune response(GO:0002920)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.3 GO:0043373 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.6 GO:0045576 mast cell activation(GO:0045576)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.7 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
0.1 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0015851 nucleobase transport(GO:0015851)
0.1 0.2 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.1 GO:0002363 B cell lineage commitment(GO:0002326) alpha-beta T cell lineage commitment(GO:0002363)
0.1 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.1 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.1 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.1 GO:0060789 hair follicle placode formation(GO:0060789)
0.1 0.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.1 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1 0.1 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.1 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.2 GO:0033622 integrin activation(GO:0033622)
0.1 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.5 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.2 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.2 GO:0070339 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.1 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.1 0.3 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.1 0.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.7 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.9 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.5 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.2 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.2 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.0 1.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.8 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 2.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.1 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.4 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.3 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.5 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 1.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.3 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.8 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0022011 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.2 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) negative regulation of glial cell proliferation(GO:0060253)
0.0 0.2 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.2 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 2.0 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.1 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0046184 aldehyde biosynthetic process(GO:0046184)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0070897 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0051900 regulation of mitochondrial depolarization(GO:0051900)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 1.6 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.0 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.7 GO:0007569 cell aging(GO:0007569)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0032365 intracellular lipid transport(GO:0032365)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.0 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.1 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.0 GO:0061043 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.0 GO:1903319 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0 0.0 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.6 GO:0007033 vacuole organization(GO:0007033)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.4 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.0 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0046174 polyol catabolic process(GO:0046174)
0.0 0.0 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.0 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.0 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.0 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.0 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.4 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.3 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.0 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.0 GO:1904377 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0015893 drug transport(GO:0015893)
0.0 0.1 GO:0006228 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 1.5 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0042269 regulation of natural killer cell mediated immunity(GO:0002715) regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.3 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.0 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:0098657 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405)
0.0 0.0 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 1.3 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.0 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.0 GO:1902622 regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0032479 regulation of type I interferon production(GO:0032479)
0.0 0.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.5 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.0 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.0 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.0 GO:0060192 negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0042401 polyamine biosynthetic process(GO:0006596) cellular biogenic amine biosynthetic process(GO:0042401)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.5 GO:0072413 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011) UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0043101 purine-containing compound salvage(GO:0043101)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 2.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 0.5 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.1 GO:0070938 contractile ring(GO:0070938)
0.1 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.3 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0030312 external encapsulating structure(GO:0030312)
0.1 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0005827 polar microtubule(GO:0005827)
0.1 0.5 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0032009 early phagosome(GO:0032009)
0.1 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.2 GO:0001740 Barr body(GO:0001740)
0.1 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.3 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 2.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.5 GO:0010008 endosome membrane(GO:0010008)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0038201 TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.0 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.0 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0044447 axoneme part(GO:0044447)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.0 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.4 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.3 GO:0000785 chromatin(GO:0000785)
0.0 0.0 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 2.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4 1.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 1.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.1 0.9 GO:0019864 IgG binding(GO:0019864)
0.1 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 2.4 GO:0003823 antigen binding(GO:0003823)
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.1 0.4 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0035197 siRNA binding(GO:0035197)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.2 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.2 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.0 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.1 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.3 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.8 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 1.0 GO:0019210 kinase inhibitor activity(GO:0019210)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 1.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.9 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.2 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.0 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.0 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.5 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.3 GO:0019825 oxygen binding(GO:0019825)
0.0 0.0 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 3.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.0 ST ADRENERGIC Adrenergic Pathway
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.7 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.0 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.5 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.0 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.0 REACTOME G1 S TRANSITION Genes involved in G1/S Transition
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+