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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SREBF1_TFE3

Z-value: 2.05

Motif logo

Transcription factors associated with SREBF1_TFE3

Gene Symbol	Gene ID	Gene Info
SREBF1 Ensembl NCBI GeneCards UniProt	ENSG00000072310.12	SREBF1
TFE3 Ensembl NCBI GeneCards UniProt	ENSG00000068323.12	TFE3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SREBF1	chr17_17739683_17740303	138	0.944474	-0.65	5.9e-02	Click!
SREBF1	chr17_17741776_17741931	1528	0.313884	0.59	9.6e-02	Click!
SREBF1	chr17_17739095_17739246	961	0.471637	-0.52	1.5e-01	Click!
SREBF1	chr17_17738870_17739021	1186	0.391260	-0.51	1.6e-01	Click!
SREBF1	chr17_17726041_17726867	478	0.731414	-0.47	2.0e-01	Click!
TFE3	chrX_48899451_48899853	1360	0.243561	0.62	7.5e-02	Click!
TFE3	chrX_48899136_48899336	1776	0.186323	0.61	8.1e-02	Click!
TFE3	chrX_48901349_48901792	558	0.576055	-0.41	2.8e-01	Click!
TFE3	chrX_48899870_48900154	1000	0.337785	0.39	3.0e-01	Click!
TFE3	chrX_48898900_48899051	2037	0.164681	0.33	3.9e-01	Click!

Activity of the SREBF1_TFE3 motif across conditions

Conditions sorted by the z-value of the SREBF1_TFE3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_243030793_243031816	1.29	AC093642.5		460	0.62
chr2_8554200_8554499	1.19	AC011747.7		261547	0.02
chr16_85793045_85793254	0.88	C16orf74	chromosome 16 open reading frame 74	8414	0.11
chr9_90134439_90134590	0.85	DAPK1	death-associated protein kinase 1	20594	0.22
chr15_101782458_101782681	0.83	CHSY1	chondroitin sulfate synthase 1	9568	0.18
chr1_180182634_180182785	0.79	LHX4	LIM homeobox 4	16712	0.19
chr16_81577563_81578015	0.76	CMIP	c-Maf inducing protein	48835	0.17
chr15_25123043_25123575	0.74	ENSG00000238615	.	15585	0.12
chr7_37723352_37723576	0.72	GPR141	G protein-coupled receptor 141	11	0.5
chr6_154800959_154801329	0.72	CNKSR3	CNKSR family member 3	1519	0.56
chr6_64062753_64063151	0.72	LGSN	lengsin, lens protein with glutamine synthetase domain	33070	0.23
chr9_90588787_90589959	0.71	CDK20	cyclin-dependent kinase 20	29	0.98
chr9_126088906_126089175	0.71	CRB2	crumbs homolog 2 (Drosophila)	29409	0.19
chr17_57408824_57410302	0.71	YPEL2	yippee-like 2 (Drosophila)	500	0.78
chr1_184775280_184775431	0.70	FAM129A	family with sequence similarity 129, member A	236	0.94
chr20_23066190_23066341	0.68	CD93	CD93 molecule	712	0.66
chr6_88875424_88876640	0.68	CNR1	cannabinoid receptor 1 (brain)	46	0.99
chr11_64267738_64267889	0.67	AP003774.4	HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185	51267	0.09
chr3_49394601_49395955	0.67	GPX1	glutathione peroxidase 1	438	0.72
chr9_134532514_134532773	0.65	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	31308	0.18
chr9_134127628_134128133	0.65	FAM78A	family with sequence similarity 78, member A	18000	0.15
chr3_58341767_58341918	0.65	PXK	PX domain containing serine/threonine kinase	22809	0.17
chr22_45124935_45125130	0.64	PRR5	proline rich 5 (renal)	1652	0.37
chr9_81760516_81760667	0.64	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	426097	0.01
chr6_90085210_90085361	0.63	UBE2J1	ubiquitin-conjugating enzyme E2, J1	22718	0.17
chrX_129086814_129087356	0.63	RP4-537K23.4		4419	0.23
chr17_74249267_74249469	0.63	UBALD2	UBA-like domain containing 2	11915	0.12
chr4_89978098_89978439	0.62	FAM13A	family with sequence similarity 13, member A	43	0.98
chr19_5627577_5627728	0.62	SAFB2	scaffold attachment factor B2	3595	0.17
chr5_133861629_133862874	0.62	JADE2	jade family PHD finger 2	76	0.97
chr4_40578981_40579556	0.61	RBM47	RNA binding motif protein 47	52613	0.14
chr8_142131426_142131715	0.60	DENND3	DENN/MADD domain containing 3	4193	0.23
chr20_30457693_30458808	0.59	DUSP15	dual specificity phosphatase 15	125	0.67
chr6_13101730_13101881	0.59	PHACTR1	phosphatase and actin regulator 1	48116	0.18
chr12_58246396_58246766	0.58	CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	6059	0.11
chr3_11610290_11610777	0.58	VGLL4	vestigial like 4 (Drosophila)	135	0.97
chr15_91429017_91429220	0.57	FES	feline sarcoma oncogene	842	0.42
chr18_74114582_74114733	0.57	ZNF516	zinc finger protein 516	23789	0.19
chr6_16675559_16675710	0.57	RP1-151F17.1		85735	0.1
chr4_682374_683342	0.57	MFSD7	major facilitator superfamily domain containing 7	74	0.94
chr2_219225143_219225442	0.57	AC021016.8		2603	0.13
chr5_134732064_134732215	0.57	H2AFY	H2A histone family, member Y	2762	0.21
chr2_30454378_30455881	0.57	LBH	limb bud and heart development	83	0.98
chr9_115513141_115514000	0.57	SNX30	sorting nexin family member 30	452	0.66
chr9_37902906_37904387	0.57	SLC25A51	solute carrier family 25, member 51	461	0.85
chr5_52098501_52098716	0.56	CTD-2288O8.1		14748	0.19
chr15_69073260_69073411	0.56	ENSG00000265195	.	20929	0.21
chr13_114064294_114064563	0.56	ADPRHL1	ADP-ribosylhydrolase like 1	39029	0.11
chr12_49595052_49595296	0.55	TUBA1A	tubulin, alpha 1a	12067	0.12
chrX_118699382_118699533	0.55	CXorf56	chromosome X open reading frame 56	60	0.97
chr1_159750747_159751482	0.55	DUSP23	dual specificity phosphatase 23	321	0.85
chr2_46925496_46926304	0.55	SOCS5	suppressor of cytokine signaling 5	191	0.95
chr6_113786265_113786416	0.55	ENSG00000222677	.	49849	0.18
chr22_24540304_24540599	0.54	CABIN1	calcineurin binding protein 1	11355	0.17
chr5_1110808_1112337	0.54	SLC12A7	solute carrier family 12 (potassium/chloride transporter), member 7	578	0.75
chr12_58146355_58146506	0.54	CDK4	cyclin-dependent kinase 4	126	0.88
chr4_75718841_75720131	0.53	BTC	betacellulin	410	0.91
chr2_242674070_242675162	0.53	AC114730.8		297	0.65
chr4_87935725_87935950	0.52	AFF1	AF4/FMR2 family, member 1	7416	0.29
chr17_76909259_76909410	0.52	TIMP2	TIMP metallopeptidase inhibitor 2	9149	0.14
chr7_100464814_100466140	0.52	TRIP6	thyroid hormone receptor interactor 6	717	0.47
chr20_1874240_1874814	0.52	SIRPA	signal-regulatory protein alpha	627	0.78
chr8_125464764_125464915	0.52	TRMT12	tRNA methyltransferase 12 homolog (S. cerevisiae)	1791	0.33
chr22_41417818_41418675	0.51	ENSG00000222698	.	23255	0.13
chr17_7218469_7219214	0.51	GPS2	G protein pathway suppressor 2	42	0.92
chr1_200329281_200329432	0.51	ZNF281	zinc finger protein 281	49764	0.18
chr17_80406652_80406803	0.51	C17orf62	chromosome 17 open reading frame 62	754	0.43
chr9_137299303_137299778	0.50	RXRA	retinoid X receptor, alpha	1112	0.59
chr20_55059093_55059344	0.50	ENSG00000238294	.	8519	0.13
chr17_32573039_32573288	0.49	CCL2	chemokine (C-C motif) ligand 2	9141	0.13
chr2_120980293_120980979	0.49	TMEM185B	transmembrane protein 185B	348	0.86
chr11_59015234_59015385	0.49	ENSG00000263999	.	33137	0.13
chr3_125321989_125322196	0.49	OSBPL11	oxysterol binding protein-like 11	8158	0.22
chr5_171056480_171056631	0.49	ENSG00000264303	.	140979	0.04
chr20_55059393_55059544	0.49	ENSG00000238294	.	8769	0.13
chr18_74300716_74301068	0.49	LINC00908	long intergenic non-protein coding RNA 908	60018	0.12
chr10_70092145_70093579	0.49	PBLD	phenazine biosynthesis-like protein domain containing	56	0.95
chr10_30842846_30843212	0.48	ENSG00000239744	.	1804	0.44
chr8_48540036_48540563	0.48	SPIDR	scaffolding protein involved in DNA repair	31927	0.18
chr12_62996165_62996975	0.47	RP11-631N16.2		38	0.9
chr10_114603535_114603686	0.47	RP11-57H14.4		20361	0.22
chr20_36343357_36343570	0.47	CTNNBL1	catenin, beta like 1	20999	0.25
chr3_4856362_4856513	0.47	ENSG00000239126	.	63949	0.12
chr6_170089936_170090087	0.47	ENSG00000265654	.	7333	0.13
chr20_352637_353070	0.47	TRIB3	tribbles pseudokinase 3	8408	0.13
chr17_8095450_8095623	0.47	C17orf59	chromosome 17 open reading frame 59	1972	0.14
chr2_109863936_109864087	0.47	ENSG00000265965	.	66070	0.13
chr15_91428234_91428460	0.47	FES	feline sarcoma oncogene	71	0.94
chr7_12726016_12726488	0.47	ARL4A	ADP-ribosylation factor-like 4A	229	0.95
chr6_56553501_56553652	0.47	DST	dystonin	45782	0.19
chr16_48655429_48655583	0.46	N4BP1	NEDD4 binding protein 1	11386	0.18
chr10_46090174_46090398	0.46	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	68	0.98
chr2_70202474_70202625	0.46	PCBP1-AS1	PCBP1 antisense RNA 1	10643	0.14
chr22_18252608_18252759	0.46	BID	BH3 interacting domain death agonist	4099	0.21
chr1_56942848_56943117	0.46	ENSG00000223307	.	99892	0.08
chr22_17305454_17306380	0.46	HSFY1P1	heat shock transcription factor, Y-linked 1 pseudogene 1	2524	0.24
chr1_68805497_68805648	0.46	WLS	wntless Wnt ligand secretion mediator	106769	0.06
chr5_149864820_149865733	0.46	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	105	0.97
chr15_23931247_23932124	0.45	NDN	necdin, melanoma antigen (MAGE) family member	765	0.7
chr3_81792766_81792994	0.45	GBE1	glucan (1,4-alpha-), branching enzyme 1	100	0.99
chr10_11189631_11189840	0.45	CELF2	CUGBP, Elav-like family member 2	17258	0.19
chr11_34469795_34470003	0.45	CAT	catalase	9427	0.22
chr16_81773052_81773267	0.45	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	457	0.89
chr19_47827930_47828081	0.45	C5AR2	complement component 5a receptor 2	7399	0.14
chr18_32828133_32828284	0.45	ZNF397	zinc finger protein 397	5771	0.24
chr3_168823048_168823199	0.45	MECOM	MDS1 and EVI1 complex locus	22699	0.28
chr2_66672542_66672972	0.45	MEIS1	Meis homeobox 1	2660	0.22
chr17_79935482_79935808	0.44	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	64	0.92
chr12_16500369_16500557	0.44	MGST1	microsomal glutathione S-transferase 1	116	0.98
chr6_45709655_45709886	0.44	ENSG00000252738	.	95929	0.09
chr19_3606102_3607092	0.44	TBXA2R	thromboxane A2 receptor	61	0.89
chr8_117127790_117127941	0.44	ENSG00000221793	.	21133	0.27
chr6_39194033_39194312	0.43	KCNK5	potassium channel, subfamily K, member 5	3054	0.34
chr17_1627660_1628132	0.43	WDR81	WD repeat domain 81	62	0.95
chr7_64895070_64895221	0.43	ZNF92	zinc finger protein 92	56351	0.13
chr21_45507595_45507746	0.43	PWP2	PWP2 periodic tryptophan protein homolog (yeast)	19501	0.16
chr4_184263832_184264346	0.43	ENSG00000238596	.	13638	0.14
chr8_8751085_8751236	0.42	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	5	0.98
chr17_76164337_76165654	0.42	SYNGR2	synaptogyrin 2	244	0.87
chr8_20060548_20060978	0.42	ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	5813	0.2
chr4_139697154_139697305	0.42	ENSG00000238971	.	35691	0.19
chr1_226890685_226891499	0.42	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	28324	0.16
chr2_68942451_68942602	0.42	ARHGAP25	Rho GTPase activating protein 25	4892	0.28
chr13_32610061_32610212	0.42	FRY-AS1	FRY antisense RNA 1	4360	0.25
chr9_86088128_86088424	0.41	ENSG00000252256	.	7906	0.21
chr15_94406450_94406737	0.41	ENSG00000222409	.	33663	0.25
chr7_151633723_151633874	0.41	RP11-796I2.1		18272	0.13
chr12_26783628_26783842	0.41	RP11-666F17.1		7433	0.31
chr13_21049820_21049971	0.41	ENSG00000263978	.	41910	0.15
chr19_58397604_58397899	0.41	ZNF814	zinc finger protein 814	2397	0.17
chr5_176733545_176733771	0.41	PRELID1	PRELI domain containing 1	1969	0.19
chr11_59534744_59534942	0.41	STX3	syntaxin 3	11918	0.14
chr16_386302_386453	0.41	AXIN1	axin 1	16072	0.1
chr20_4791451_4791602	0.40	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	4243	0.24
chr19_13906290_13907522	0.40	ZSWIM4	zinc finger, SWIM-type containing 4	632	0.39
chrX_10126292_10126538	0.40	CLCN4	chloride channel, voltage-sensitive 4	73	0.98
chr17_62914990_62915617	0.40	LRRC37A3	leucine rich repeat containing 37, member A3	283	0.85
chr17_34417289_34417440	0.40	CCL3	chemokine (C-C motif) ligand 3	123	0.91
chr11_47963912_47964063	0.40	PTPRJ	protein tyrosine phosphatase, receptor type, J	38126	0.15
chr15_41913046_41914152	0.40	MGA	MGA, MAX dimerization protein	135	0.96
chr14_22898080_22898287	0.40	ENSG00000251002	.	3536	0.15
chr1_155734495_155734646	0.40	DAP3	death associated protein 3	27767	0.13
chr5_124082726_124083211	0.40	ZNF608	zinc finger protein 608	648	0.62
chr10_134388453_134389007	0.40	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	32700	0.18
chr10_112063891_112064934	0.40	SMNDC1	survival motor neuron domain containing 1	43	0.98
chr13_113864349_113864894	0.40	CUL4A	cullin 4A	763	0.52
chr14_100763795_100764125	0.40	SLC25A29	solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29	1078	0.29
chr2_27301899_27302732	0.39	EMILIN1	elastin microfibril interfacer 1	880	0.32
chr16_30133730_30134408	0.39	MAPK3	mitogen-activated protein kinase 3	220	0.84
chr8_6149062_6149390	0.39	RP11-115C21.2		114837	0.06
chr6_41905004_41905155	0.39	CCND3	cyclin D3	3385	0.17
chr10_101754254_101754405	0.39	DNMBP	dynamin binding protein	15347	0.18
chrX_119693723_119694790	0.39	CUL4B	cullin 4B	299	0.9
chr11_32851440_32852005	0.39	PRRG4	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)	233	0.94
chr19_21657403_21658104	0.39	ZNF429	zinc finger protein 429	30613	0.19
chr11_128643013_128643164	0.39	FLI1	Fli-1 proto-oncogene, ETS transcription factor	8403	0.23
chr3_49055259_49056395	0.39	DALRD3	DALR anticodon binding domain containing 3	170	0.84
chr15_99091192_99092106	0.39	FAM169B	family with sequence similarity 169, member B	34038	0.21
chr19_40228193_40228344	0.38	CLC	Charcot-Leyden crystal galectin	400	0.8
chr10_81961619_81961770	0.38	ANXA11	annexin A11	2553	0.3
chr16_48653764_48653915	0.38	N4BP1	NEDD4 binding protein 1	9719	0.19
chr11_45943886_45945188	0.38	GYLTL1B	glycosyltransferase-like 1B	208	0.9
chr3_183258604_183258863	0.38	KLHL6-AS1	KLHL6 antisense RNA 1	7790	0.17
chr6_34150802_34151099	0.38	GRM4	glutamate receptor, metabotropic 4	27551	0.18
chr1_192128557_192128890	0.38	RGS18	regulator of G-protein signaling 18	1136	0.67
chr8_142247794_142247945	0.38	SLC45A4	solute carrier family 45, member 4	7422	0.16
chr6_133076946_133077097	0.38	VNN2	vanin 2	2001	0.21
chr18_60779992_60780143	0.38	RP11-299P2.1		38486	0.19
chr2_160653969_160654659	0.38	CD302	CD302 molecule	439	0.87
chr8_142099374_142099525	0.38	DENND3	DENN/MADD domain containing 3	27928	0.18
chr9_140500205_140501463	0.37	ARRDC1	arrestin domain containing 1	679	0.56
chr7_120633783_120633934	0.37	CPED1	cadherin-like and PC-esterase domain containing 1	4182	0.23
chrX_48930794_48931951	0.37	PRAF2	PRA1 domain family, member 2	276	0.78
chr9_94173775_94173926	0.37	NFIL3	nuclear factor, interleukin 3 regulated	12294	0.27
chr6_132236251_132236458	0.37	RP11-69I8.3		35732	0.16
chr5_154026662_154027279	0.37	ENSG00000221552	.	38366	0.13
chr1_28230856_28231007	0.37	RPA2	replication protein A2, 32kDa	7335	0.12
chr22_32033982_32034378	0.37	PISD	phosphatidylserine decarboxylase	211	0.94
chrX_153206750_153207141	0.37	RENBP	renin binding protein	1277	0.25
chr8_126619901_126620052	0.37	ENSG00000266452	.	163169	0.04
chr11_34448298_34448762	0.37	CAT	catalase	11942	0.23
chr20_42704509_42704660	0.36	TOX2	TOX high mobility group box family member 2	21593	0.21
chrX_109330942_109331348	0.36	ENSG00000265584	.	5799	0.25
chr19_45254003_45254720	0.36	BCL3	B-cell CLL/lymphoma 3	217	0.88
chr2_60711731_60711882	0.36	AC009970.1		11015	0.25
chr12_7064003_7064154	0.36	PTPN6	protein tyrosine phosphatase, non-receptor type 6	3540	0.07
chr2_145265883_145266282	0.36	ZEB2	zinc finger E-box binding homeobox 2	9033	0.25
chr20_4795670_4795862	0.36	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	3	0.98
chr19_43072102_43072253	0.36	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	6791	0.2
chr9_140335891_140336276	0.36	ENTPD8	ectonucleoside triphosphate diphosphohydrolase 8	182	0.91
chr19_29479808_29479959	0.36	ENSG00000252272	.	12694	0.27
chr10_22898838_22898989	0.36	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	18271	0.27
chrX_102318388_102319159	0.36	BEX1	brain expressed, X-linked 1	395	0.83
chr12_111136320_111136489	0.36	HVCN1	hydrogen voltage-gated channel 1	6351	0.19
chr17_76382081_76382638	0.36	PGS1	phosphatidylglycerophosphate synthase 1	7600	0.14
chr7_37724366_37724517	0.36	GPR141	G protein-coupled receptor 141	966	0.42
chr12_122750287_122751110	0.36	VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)	265	0.91
chr11_16213287_16213568	0.36	ENSG00000221556	.	67565	0.14
chr1_110008824_110009670	0.36	SYPL2	synaptophysin-like 2	3	0.96
chr19_6802455_6802606	0.36	VAV1	vav 1 guanine nucleotide exchange factor	18401	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.7	GO:0045759	negative regulation of action potential(GO:0045759)
0.2	0.6	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.2	0.6	GO:0030210	heparin biosynthetic process(GO:0030210)
0.2	0.8	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.6	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.5	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.6	GO:0016246	RNA interference(GO:0016246)
0.1	0.3	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.8	GO:0010269	response to selenium ion(GO:0010269)
0.1	0.4	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1	0.2	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.3	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.3	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.7	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.1	0.9	GO:0042119	neutrophil activation(GO:0042119)
0.1	0.4	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	0.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.4	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.1	0.2	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.2	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.1	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.2	GO:0060242	contact inhibition(GO:0060242)
0.1	0.4	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.4	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.1	0.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.2	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.2	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1	0.3	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.2	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.1	GO:0050942	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.1	0.2	GO:2000831	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.1	0.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.1	0.3	GO:0007549	dosage compensation(GO:0007549)
0.1	0.3	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.3	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.2	GO:0006824	cobalt ion transport(GO:0006824)
0.1	0.1	GO:0030202	heparin metabolic process(GO:0030202)
0.1	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.1	0.2	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.1	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.1	0.1	GO:0052306	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1	0.1	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
0.1	0.3	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.1	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.1	0.1	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1	0.6	GO:0032418	lysosome localization(GO:0032418)
0.1	0.2	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1	0.4	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.1	0.3	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	0.2	GO:0031054	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) pre-miRNA processing(GO:0031054)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.1	GO:0034405	response to fluid shear stress(GO:0034405)
0.1	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.1	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1	0.3	GO:0008354	germ cell migration(GO:0008354)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.3	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.0	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.2	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.3	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.1	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.2	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.0	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.3	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.3	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.0	GO:0071221	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0032490	detection of molecule of bacterial origin(GO:0032490)
0.0	0.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0008218	bioluminescence(GO:0008218)
0.0	0.2	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.0	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.4	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.2	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.3	GO:0060039	pericardium development(GO:0060039)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.5	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.4	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0021853	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.2	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.2	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0052509	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0051852	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.3	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.3	GO:0030728	ovulation(GO:0030728)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.7	GO:0006692	prostanoid metabolic process(GO:0006692)
0.0	0.3	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.2	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.0	0.3	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.2	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	0.5	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.2	GO:0010664	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.3	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.3	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.3	GO:0007141	male meiosis I(GO:0007141)
0.0	0.2	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.3	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.2	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.2	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.2	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.4	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0090398	cellular senescence(GO:0090398)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.2	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0014009	glial cell proliferation(GO:0014009)
0.0	0.1	GO:0021794	thalamus development(GO:0021794)
0.0	0.2	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.3	GO:0006195	purine nucleotide catabolic process(GO:0006195)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0	0.2	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0060323	head morphogenesis(GO:0060323)
0.0	0.0	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.5	GO:0060048	cardiac muscle contraction(GO:0060048)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.5	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.3	GO:0032438	melanosome organization(GO:0032438)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.4	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.3	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.6	GO:0006909	phagocytosis(GO:0006909)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0006595	polyamine metabolic process(GO:0006595)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.0	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0021508	floor plate formation(GO:0021508)
0.0	0.0	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.3	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.2	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.0	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.0	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.0	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.0	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.2	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.0	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.5	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0014002	astrocyte development(GO:0014002)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.4	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0010822	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.4	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:1902743	regulation of lamellipodium organization(GO:1902743)
0.0	0.0	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.2	GO:0050935	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0	0.0	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.2	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.2	GO:0042401	polyamine biosynthetic process(GO:0006596) cellular biogenic amine biosynthetic process(GO:0042401)
0.0	0.1	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.5	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.0	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0098543	detection of other organism(GO:0098543)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.0	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.0	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.1	GO:0006940	regulation of smooth muscle contraction(GO:0006940)
0.0	0.1	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.0	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.2	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.0	GO:0015669	gas transport(GO:0015669)
0.0	0.0	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0045069	regulation of viral genome replication(GO:0045069)
0.0	0.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0051883	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.1	GO:0061365	positive regulation of lipoprotein lipase activity(GO:0051006) positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.4	GO:0008366	ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.2	GO:0050728	negative regulation of inflammatory response(GO:0050728)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:1902117	positive regulation of organelle assembly(GO:1902117)
0.0	0.0	GO:0060004	reflex(GO:0060004)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0035094	response to nicotine(GO:0035094)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.2	GO:0019400	alditol metabolic process(GO:0019400)
0.0	0.1	GO:0048247	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.0	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.2	GO:0009268	response to pH(GO:0009268)
0.0	0.0	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.2	GO:0030317	sperm motility(GO:0030317)
0.0	0.0	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0031116	positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.0	0.6	GO:0006826	iron ion transport(GO:0006826)
0.0	0.0	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.0	GO:0009309	amine biosynthetic process(GO:0009309)
0.0	0.0	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0031670	cellular response to nutrient(GO:0031670)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:0034227	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0042629	mast cell granule(GO:0042629)
0.1	0.6	GO:0043218	compact myelin(GO:0043218)
0.1	0.4	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.4	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.4	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.3	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	0.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	0.3	GO:0001740	Barr body(GO:0001740)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.7	GO:0042581	specific granule(GO:0042581)
0.1	0.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.2	GO:0000800	lateral element(GO:0000800)
0.1	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.3	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.1	0.2	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.4	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.3	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	1.2	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.4	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.6	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.4	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.9	GO:0030027	lamellipodium(GO:0030027)
0.0	0.5	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.2	0.6	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.2	0.5	GO:0001849	complement component C1q binding(GO:0001849)
0.2	0.6	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.5	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.5	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.4	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.4	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.3	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.3	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.2	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.2	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0004370	glycerol kinase activity(GO:0004370)
0.1	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.2	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.2	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.4	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.2	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.1	GO:0001846	opsonin binding(GO:0001846)
0.1	0.2	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1	0.5	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.2	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.5	GO:0004954	prostanoid receptor activity(GO:0004954)
0.1	0.2	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.1	0.4	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.2	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.3	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.1	0.2	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.1	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.6	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.5	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.6	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.3	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.4	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.7	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.5	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.7	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.2	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.9	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0004953	icosanoid receptor activity(GO:0004953)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.3	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.3	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.0	GO:0003916	DNA topoisomerase activity(GO:0003916)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.4	GO:0004601	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0	0.2	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.0	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.0	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.0	0.2	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.4	GO:0008009	chemokine activity(GO:0008009)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	0.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	1.9	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.5	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.7	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.6	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	1.0	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.5	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.9	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.9	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.5	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.5	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.8	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.4	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.4	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.0	REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	Genes involved in Insulin receptor signalling cascade
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.6	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.3	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing