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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for SREBF2

Z-value: 0.75

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Transcription factors associated with SREBF2

Gene Symbol Gene ID Gene Info
SREBF2
ENSG00000198911.7 sterol regulatory element binding transcription factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr22_42228231_42228382SREBF28030.4808850.324.0e-01Click!
chr22_42229173_42229736SREBF23450.756595-0.196.3e-01Click!
chr22_42228451_42228869SREBF24490.7087000.117.9e-01Click!

Activity of the SREBF2 motif across conditions

Conditions sorted by the z-value of the SREBF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_67172347_67172531 0.55 TBC1D10C
 TBC1 domain family, member 10C
 779
 0.35
chr17_56408210_56408765 0.45 MIR142
 microRNA 142
 192
 0.87
chr17_2680216_2680485 0.38 RAP1GAP2
 RAP1 GTPase activating protein 2
 0
 0.97
chr7_1978940_1979381 0.36 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 1025
 0.64
chr3_111851121_111851374 0.35 GCSAM
 germinal center-associated, signaling and motility
 825
 0.44
chr20_58631308_58631666 0.34 C20orf197
 chromosome 20 open reading frame 197
 507
 0.85
chr1_241715191_241715459 0.34 KMO
 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
 16610
 0.2
chrX_49117374_49117525 0.34 FOXP3
 forkhead box P3
 1752
 0.19
chr17_79261408_79261559 0.33 SLC38A10
 solute carrier family 38, member 10
 5419
 0.14
chr2_113932645_113932882 0.33 AC016683.5
151
 0.91
chr4_6918168_6918454 0.33 TBC1D14
 TBC1 domain family, member 14
 6336
 0.19
chr7_50356004_50356399 0.31 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 7883
 0.3
chr17_38720511_38720770 0.30 CCR7
 chemokine (C-C motif) receptor 7
 1071
 0.49
chr5_171600666_171600940 0.29 STK10
 serine/threonine kinase 10
 14587
 0.19
chr21_47035971_47036122 0.28 PCBP3
 poly(rC) binding protein 3
 27562
 0.2
chr10_127688132_127688283 0.27 FANK1
 fibronectin type III and ankyrin repeat domains 1
 4221
 0.25
chr5_36725036_36725307 0.26 CTD-2353F22.1
104
 0.98
chr21_36418295_36418575 0.24 RUNX1
 runt-related transcription factor 1
 3027
 0.41
chr4_84034679_84034947 0.24 PLAC8
 placenta-specific 8
 1055
 0.6
chr3_112215334_112215665 0.23 BTLA
 B and T lymphocyte associated
 2706
 0.33
chr17_72211874_72212025 0.23 TTYH2
 tweety family member 2
 194
 0.91
chr9_139925276_139925479 0.23 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 2085
 0.1
chr22_37616154_37616305 0.23 SSTR3
 somatostatin receptor 3
 7867
 0.13
chr22_18260050_18260218 0.22 BID
 BH3 interacting domain death agonist
 2703
 0.26
chr2_38607378_38607679 0.22 ATL2
 atlastin GTPase 2
 3101
 0.37
chr19_1040639_1041023 0.22 ABCA7
 ATP-binding cassette, sub-family A (ABC1), member 7
 370
 0.68
chr12_6570416_6570672 0.22 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
 9267
 0.08
chr12_111099649_111099800 0.22 TCTN1
 tectonic family member 1
 20870
 0.13
chr1_31228309_31228562 0.21 LAPTM5
 lysosomal protein transmembrane 5
 2232
 0.26
chr19_7413904_7414409 0.21 CTB-133G6.1
308
 0.88
chr20_31099035_31099434 0.21 C20orf112
 chromosome 20 open reading frame 112
 24
 0.98
chr4_3303508_3303659 0.20 RGS12
 regulator of G-protein signaling 12
 7179
 0.25
chr2_8519851_8520002 0.20 AC011747.7
295970
 0.01
chr3_101504129_101504461 0.19 NXPE3
 neurexophilin and PC-esterase domain family, member 3
 51
 0.97
chr3_121378552_121379115 0.19 HCLS1
 hematopoietic cell-specific Lyn substrate 1
 912
 0.5
chr17_70715496_70715723 0.18 ENSG00000222545
 .
 4999
 0.28
chr12_4381475_4382675 0.18 CCND2
 cyclin D2
 863
 0.52
chr12_10096266_10096511 0.18 CLEC12A
 C-type lectin domain family 12, member A
 7527
 0.14
chr3_5019013_5019527 0.18 BHLHE40
 basic helix-loop-helix family, member e40
 1531
 0.38
chr10_126417275_126417426 0.18 FAM53B
 family with sequence similarity 53, member B
 14189
 0.16
chr16_88748267_88748717 0.18 SNAI3-AS1
 SNAI3 antisense RNA 1
 3049
 0.1
chr22_39638272_39638423 0.18 PDGFB
 platelet-derived growth factor beta polypeptide
 674
 0.63
chr20_23064979_23065243 0.17 CD93
 CD93 molecule
 1866
 0.32
chr8_38216839_38216990 0.17 WHSC1L1
 Wolf-Hirschhorn syndrome candidate 1-like 1
 21425
 0.11
chr11_67036883_67037040 0.17 ADRBK1
 adrenergic, beta, receptor kinase 1
 3009
 0.16
chr15_63798871_63799191 0.17 USP3
 ubiquitin specific peptidase 3
 2176
 0.37
chr22_37542366_37542517 0.16 IL2RB
 interleukin 2 receptor, beta
 3589
 0.14
chr2_197047793_197047944 0.16 STK17B
 serine/threonine kinase 17b
 6641
 0.2
chr11_44326896_44327745 0.16 ALX4
 ALX homeobox 4
 4396
 0.34
chr12_104856651_104856876 0.16 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 5984
 0.3
chr2_10169783_10169983 0.15 KLF11
 Kruppel-like factor 11
 13093
 0.13
chr5_169724277_169724686 0.15 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 750
 0.71
chr15_40397944_40398095 0.15 BMF
 Bcl2 modifying factor
 268
 0.9
chr21_45341679_45341830 0.15 ENSG00000199598
 .
 1972
 0.29
chr19_8274834_8275489 0.15 CERS4
 ceramide synthase 4
 643
 0.68
chr6_33610158_33610417 0.15 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
 21126
 0.13
chr1_158901311_158901684 0.15 PYHIN1
 pyrin and HIN domain family, member 1
 139
 0.97
chr8_38663717_38663929 0.15 TACC1
 transforming, acidic coiled-coil containing protein 1
 855
 0.58
chr7_1550821_1550972 0.15 AC102953.6
1833
 0.26
chr17_29644174_29644325 0.15 CTD-2370N5.3
1409
 0.29
chr14_75085047_75085411 0.15 LTBP2
 latent transforming growth factor beta binding protein 2
 5923
 0.21
chr1_19253687_19254204 0.15 IFFO2
 intermediate filament family orphan 2
 15459
 0.16
chr14_99699001_99699256 0.15 AL109767.1
30157
 0.18
chr17_45814129_45814344 0.15 TBX21
 T-box 21
 3626
 0.18
chr2_43401435_43401586 0.14 ZFP36L2
 ZFP36 ring finger protein-like 2
 52238
 0.14
chr7_105711766_105712098 0.14 SYPL1
 synaptophysin-like 1
 26376
 0.22
chr9_139923953_139924104 0.14 ABCA2
 ATP-binding cassette, sub-family A (ABC1), member 2
 1288
 0.16
chr10_126916601_126916752 0.14 CTBP2
 C-terminal binding protein 2
 67046
 0.13
chr19_7770859_7771101 0.14 FCER2
 Fc fragment of IgE, low affinity II, receptor for (CD23)
 3948
 0.11
chr9_71783775_71784020 0.14 TJP2
 tight junction protein 2
 5184
 0.29
chr1_150532769_150532920 0.14 ADAMTSL4-AS1
 ADAMTSL4 antisense RNA 1
 1125
 0.26
chr6_34360722_34361201 0.14 NUDT3
 nudix (nucleoside diphosphate linked moiety X)-type motif 3
 510
 0.78
chr22_39493450_39493612 0.14 APOBEC3H
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
 251
 0.88
chr14_22955216_22955367 0.14 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 880
 0.4
chrX_153094909_153095060 0.14 PDZD4
 PDZ domain containing 4
 367
 0.75
chrX_110366573_110366760 0.14 PAK3
 p21 protein (Cdc42/Rac)-activated kinase 3
 361
 0.93
chr1_198651611_198651863 0.13 RP11-553K8.5
15547
 0.24
chr1_12124202_12124372 0.13 TNFRSF8
 tumor necrosis factor receptor superfamily, member 8
 760
 0.56
chr7_41921705_41921953 0.13 AC005027.3
176896
 0.03
chr19_39825870_39826313 0.13 GMFG
 glia maturation factor, gamma
 554
 0.58
chr2_232571958_232572632 0.13 PTMA
 prothymosin, alpha
 99
 0.91
chr22_31886169_31886386 0.13 EIF4ENIF1
 eukaryotic translation initiation factor 4E nuclear import factor 1
 354
 0.81
chr5_909418_909569 0.13 TRIP13
 thyroid hormone receptor interactor 13
 15736
 0.15
chr16_56691251_56692352 0.13 MT1F
 metallothionein 1F
 54
 0.92
chr8_27183780_27184189 0.13 PTK2B
 protein tyrosine kinase 2 beta
 356
 0.89
chr4_2800321_2800472 0.13 SH3BP2
 SH3-domain binding protein 2
 105
 0.97
chr8_95956181_95956332 0.12 TP53INP1
 tumor protein p53 inducible nuclear protein 1
 3055
 0.18
chr17_47840030_47840441 0.12 FAM117A
 family with sequence similarity 117, member A
 1258
 0.41
chr6_41998934_41999085 0.12 ENSG00000206875
 .
 12757
 0.15
chr12_123513254_123513405 0.12 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 5872
 0.15
chr5_126094279_126094440 0.12 ENSG00000252185
 .
 3250
 0.29
chr6_27661627_27662566 0.12 ENSG00000238648
 .
 62908
 0.08
chr12_9911079_9911493 0.12 CD69
 CD69 molecule
 2211
 0.26
chr19_2620958_2621288 0.12 CTC-265F19.2
9263
 0.14
chr7_100223660_100223811 0.12 TFR2
 transferrin receptor 2
 6992
 0.09
chr11_122567611_122567762 0.12 ENSG00000239079
 .
 29333
 0.19
chr18_60087506_60087670 0.12 RP11-640A1.3
42225
 0.16
chr18_20651331_20651482 0.12 ENSG00000223023
 .
 46847
 0.11
chr15_92392813_92392964 0.12 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 4037
 0.29
chr12_131272457_131272715 0.11 ENSG00000238822
 .
 27312
 0.17
chr11_117856643_117857627 0.11 IL10RA
 interleukin 10 receptor, alpha
 26
 0.98
chr2_74743098_74743363 0.11 TLX2
 T-cell leukemia homeobox 2
 1619
 0.14
chr1_160680158_160680309 0.11 CD48
 CD48 molecule
 1360
 0.38
chr1_1141210_1141593 0.11 TNFRSF18
 tumor necrosis factor receptor superfamily, member 18
 341
 0.72
chr19_14277944_14278210 0.11 LPHN1
 latrophilin 1
 5729
 0.13
chr9_130319902_130320178 0.11 FAM129B
 family with sequence similarity 129, member B
 11327
 0.17
chr9_123682878_123683088 0.11 TRAF1
 TNF receptor-associated factor 1
 6133
 0.22
chrX_78621891_78622920 0.11 ITM2A
 integral membrane protein 2A
 451
 0.91
chr5_95152547_95152698 0.11 GLRX
 glutaredoxin (thioltransferase)
 5793
 0.16
chr2_8627682_8628105 0.11 AC011747.7
188003
 0.03
chrX_39501672_39501823 0.11 ENSG00000263730
 .
 18723
 0.29
chr21_44820304_44820455 0.11 SIK1
 salt-inducible kinase 1
 26629
 0.24
chr1_22463869_22464020 0.11 WNT4
 wingless-type MMTV integration site family, member 4
 5515
 0.23
chr7_50350295_50350528 0.11 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 2093
 0.45
chr18_77159141_77159292 0.11 NFATC1
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
 1106
 0.59
chr9_95895594_95896005 0.11 NINJ1
 ninjurin 1
 771
 0.63
chr12_122237162_122237447 0.11 RHOF
 ras homolog family member F (in filopodia)
 1279
 0.39
chr1_155231583_155232074 0.11 SCAMP3
 secretory carrier membrane protein 3
 222
 0.81
chr6_119634064_119634215 0.11 ENSG00000200732
 .
 14307
 0.25
chr14_100770611_100770762 0.11 SLC25A29
 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
 2092
 0.14
chr15_75082884_75083035 0.10 ENSG00000264386
 .
 1861
 0.2
chr18_77161034_77161555 0.10 NFATC1
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
 902
 0.67
chr17_57515063_57515214 0.10 RP11-567L7.5
34474
 0.15
chr6_45345006_45345267 0.10 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 534
 0.83
chr17_76771045_76771282 0.10 CYTH1
 cytohesin 1
 7191
 0.19
chr12_48398455_48398676 0.10 COL2A1
 collagen, type II, alpha 1
 296
 0.86
chr16_68390170_68390671 0.10 SMPD3
 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
 14488
 0.11
chr7_1051859_1052010 0.10 ENSG00000199023
 .
 10728
 0.1
chr3_128523693_128523920 0.10 RAB7A
 RAB7A, member RAS oncogene family
 9604
 0.18
chr9_132222026_132222209 0.10 ENSG00000264298
 .
 18718
 0.2
chr6_167507024_167507239 0.10 CCR6
 chemokine (C-C motif) receptor 6
 18164
 0.18
chr3_71478867_71479018 0.10 ENSG00000221264
 .
 112298
 0.06
chr17_80063977_80064793 0.10 CCDC57
 coiled-coil domain containing 57
 4659
 0.1
chr9_134113693_134114226 0.10 NUP214
 nucleoporin 214kDa
 10278
 0.17
chr17_48217501_48218008 0.10 AC002401.1
4803
 0.11
chr22_25960035_25960186 0.10 CTA-407F11.8
7
 0.93
chr2_143885996_143886303 0.10 ARHGAP15
 Rho GTPase activating protein 15
 734
 0.76
chr1_47048198_47048369 0.10 MKNK1
 MAP kinase interacting serine/threonine kinase 1
 2949
 0.2
chr12_12867727_12867916 0.10 CDKN1B
 cyclin-dependent kinase inhibitor 1B (p27, Kip1)
 2237
 0.23
chr3_183852600_183853095 0.10 RP11-778D9.12
122
 0.61
chr22_44578201_44578448 0.10 PARVG
 parvin, gamma
 583
 0.83
chr17_80229441_80229710 0.10 CSNK1D
 casein kinase 1, delta
 1729
 0.23
chr3_14241386_14241537 0.10 XPC
 xeroderma pigmentosum, complementation group C
 21178
 0.17
chr13_37574524_37574865 0.10 EXOSC8
 exosome component 8
 16
 0.96
chr3_128734717_128734917 0.10 EFCC1
 EF-hand and coiled-coil domain containing 1
 14345
 0.13
chr5_156700321_156700472 0.10 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 4034
 0.17
chr8_134071502_134071774 0.10 SLA
 Src-like-adaptor
 965
 0.65
chr22_38036611_38036887 0.10 SH3BP1
 SH3-domain binding protein 1
 722
 0.49
chr2_233925739_233925978 0.10 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
 669
 0.7
chr9_5832277_5833455 0.10 ERMP1
 endoplasmic reticulum metallopeptidase 1
 251
 0.93
chr10_25176560_25176711 0.09 ENSG00000240294
 .
 21106
 0.23
chr10_106083582_106083733 0.09 ITPRIP
 inositol 1,4,5-trisphosphate receptor interacting protein
 5025
 0.15
chr1_154379631_154380335 0.09 RP11-350G8.5
943
 0.42
chr2_204572488_204572658 0.09 CD28
 CD28 molecule
 1157
 0.58
chr20_57266602_57266883 0.09 NPEPL1
 aminopeptidase-like 1
 927
 0.53
chr9_130546021_130546292 0.09 CDK9
 cyclin-dependent kinase 9
 1802
 0.16
chr1_44873108_44873259 0.09 RNF220
 ring finger protein 220
 2223
 0.29
chr7_154997328_154997479 0.09 AC099552.4
 Uncharacterized protein
 7257
 0.22
chr14_23341701_23341904 0.09 LRP10
 low density lipoprotein receptor-related protein 10
 289
 0.77
chr17_9549466_9549768 0.09 USP43
 ubiquitin specific peptidase 43
 763
 0.39
chr14_35303482_35303633 0.09 ENSG00000251726
 .
 11009
 0.17
chr16_70286070_70286221 0.09 EXOSC6
 exosome component 6
 312
 0.77
chr13_91827106_91827257 0.09 ENSG00000215417
 .
 175678
 0.04
chr12_68775706_68775857 0.09 MDM1
 Mdm1 nuclear protein homolog (mouse)
 49620
 0.17
chr11_112096740_112097015 0.09 PTS
 6-pyruvoyltetrahydropterin synthase
 211
 0.89
chr1_12244133_12244323 0.09 ENSG00000263676
 .
 7542
 0.16
chrX_23872431_23872582 0.09 APOO
 apolipoprotein O
 26512
 0.15
chr3_112323750_112323901 0.09 CCDC80
 coiled-coil domain containing 80
 5302
 0.24
chr7_102044904_102045055 0.09 ENSG00000221510
 .
 1323
 0.27
chr2_85806418_85806569 0.09 VAMP8
 vesicle-associated membrane protein 8
 1777
 0.17
chr13_78272907_78273541 0.09 SLAIN1
 SLAIN motif family, member 1
 207
 0.89
chr8_131020590_131020791 0.09 ENSG00000264653
 .
 9
 0.97
chr9_140171799_140172072 0.09 TOR4A
 torsin family 4, member A
 266
 0.79
chr9_92786212_92786363 0.09 ENSG00000263967
 .
 470
 0.9
chr2_241390296_241390447 0.09 GPC1
 glypican 1
 1857
 0.28
chr1_226920663_226921046 0.09 ITPKB
 inositol-trisphosphate 3-kinase B
 4305
 0.27
chr4_75263884_75264078 0.09 EREG
 epiregulin
 33121
 0.14
chr10_90754998_90755312 0.09 ACTA2
 actin, alpha 2, smooth muscle, aorta
 4008
 0.17
chr16_31411645_31411796 0.09 RP11-120K18.2
2166
 0.18
chr6_15245727_15246152 0.09 JARID2
 jumonji, AT rich interactive domain 2
 588
 0.74
chr3_13462664_13462815 0.09 NUP210
 nucleoporin 210kDa
 930
 0.65
chr22_22293537_22293770 0.08 PPM1F
 protein phosphatase, Mg2+/Mn2+ dependent, 1F
 697
 0.45
chr9_139929070_139929505 0.08 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 1825
 0.11
chr9_79265748_79266757 0.08 PRUNE2
 prune homolog 2 (Drosophila)
 1213
 0.53
chr3_71751711_71751862 0.08 EIF4E3
 eukaryotic translation initiation factor 4E family member 3
 22740
 0.2
chr22_20225722_20225873 0.08 RTN4R
 reticulon 4 receptor
 5410
 0.14
chr2_233179871_233180040 0.08 DIS3L2
 DIS3 mitotic control homolog (S. cerevisiae)-like 2
 18698
 0.17
chr18_72166510_72167447 0.08 CNDP2
 CNDP dipeptidase 2 (metallopeptidase M20 family)
 118
 0.97
chr1_111174065_111174216 0.08 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
 44
 0.98
chr17_38769482_38769633 0.08 SMARCE1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
 18985
 0.13
chr12_124950039_124950191 0.08 NCOR2
 nuclear receptor corepressor 2
 18200
 0.28
chr11_67857787_67857938 0.08 CHKA
 choline kinase alpha
 30433
 0.1
chr12_122239467_122240363 0.08 RHOF
 ras homolog family member F (in filopodia)
 919
 0.49
chr17_75450826_75450977 0.08 SEPT9
 septin 9
 739
 0.6
chr10_53458598_53459393 0.08 CSTF2T
 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
 360
 0.92
chr2_144941449_144941842 0.08 GTDC1
 glycosyltransferase-like domain containing 1
 51659
 0.18
chr1_19805004_19805155 0.08 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 5500
 0.18
chr1_200989934_200990087 0.08 KIF21B
 kinesin family member 21B
 2526
 0.27
chr17_36860259_36860862 0.08 MLLT6
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
 1235
 0.2
chr19_41857713_41858218 0.08 TMEM91
 transmembrane protein 91
 1149
 0.27

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions