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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SREBF2

Z-value: 0.75

Motif logo

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Transcription factors associated with SREBF2

Gene Symbol Gene ID Gene Info
ENSG00000198911.7 SREBF2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
SREBF2chr22_42228231_422283828030.4808850.324.0e-01Click!
SREBF2chr22_42229173_422297363450.756595-0.196.3e-01Click!
SREBF2chr22_42228451_422288694490.7087000.117.9e-01Click!

Activity of the SREBF2 motif across conditions

Conditions sorted by the z-value of the SREBF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_67172347_67172531 0.55 TBC1D10C
TBC1 domain family, member 10C
779
0.35
chr17_56408210_56408765 0.45 MIR142
microRNA 142
192
0.87
chr17_2680216_2680485 0.38 RAP1GAP2
RAP1 GTPase activating protein 2
0
0.97
chr7_1978940_1979381 0.36 MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
1025
0.64
chr3_111851121_111851374 0.35 GCSAM
germinal center-associated, signaling and motility
825
0.44
chr20_58631308_58631666 0.34 C20orf197
chromosome 20 open reading frame 197
507
0.85
chr1_241715191_241715459 0.34 KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
16610
0.2
chrX_49117374_49117525 0.34 FOXP3
forkhead box P3
1752
0.19
chr17_79261408_79261559 0.33 SLC38A10
solute carrier family 38, member 10
5419
0.14
chr2_113932645_113932882 0.33 AC016683.5

151
0.91
chr4_6918168_6918454 0.33 TBC1D14
TBC1 domain family, member 14
6336
0.19
chr7_50356004_50356399 0.31 IKZF1
IKAROS family zinc finger 1 (Ikaros)
7883
0.3
chr17_38720511_38720770 0.30 CCR7
chemokine (C-C motif) receptor 7
1071
0.49
chr5_171600666_171600940 0.29 STK10
serine/threonine kinase 10
14587
0.19
chr21_47035971_47036122 0.28 PCBP3
poly(rC) binding protein 3
27562
0.2
chr10_127688132_127688283 0.27 FANK1
fibronectin type III and ankyrin repeat domains 1
4221
0.25
chr5_36725036_36725307 0.26 CTD-2353F22.1

104
0.98
chr21_36418295_36418575 0.24 RUNX1
runt-related transcription factor 1
3027
0.41
chr4_84034679_84034947 0.24 PLAC8
placenta-specific 8
1055
0.6
chr3_112215334_112215665 0.23 BTLA
B and T lymphocyte associated
2706
0.33
chr17_72211874_72212025 0.23 TTYH2
tweety family member 2
194
0.91
chr9_139925276_139925479 0.23 FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
2085
0.1
chr22_37616154_37616305 0.23 SSTR3
somatostatin receptor 3
7867
0.13
chr22_18260050_18260218 0.22 BID
BH3 interacting domain death agonist
2703
0.26
chr2_38607378_38607679 0.22 ATL2
atlastin GTPase 2
3101
0.37
chr19_1040639_1041023 0.22 ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
370
0.68
chr12_6570416_6570672 0.22 VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
9267
0.08
chr12_111099649_111099800 0.22 TCTN1
tectonic family member 1
20870
0.13
chr1_31228309_31228562 0.21 LAPTM5
lysosomal protein transmembrane 5
2232
0.26
chr19_7413904_7414409 0.21 CTB-133G6.1

308
0.88
chr20_31099035_31099434 0.21 C20orf112
chromosome 20 open reading frame 112
24
0.98
chr4_3303508_3303659 0.20 RGS12
regulator of G-protein signaling 12
7179
0.25
chr2_8519851_8520002 0.20 AC011747.7

295970
0.01
chr3_101504129_101504461 0.19 NXPE3
neurexophilin and PC-esterase domain family, member 3
51
0.97
chr3_121378552_121379115 0.19 HCLS1
hematopoietic cell-specific Lyn substrate 1
912
0.5
chr17_70715496_70715723 0.18 ENSG00000222545
.
4999
0.28
chr12_4381475_4382675 0.18 CCND2
cyclin D2
863
0.52
chr12_10096266_10096511 0.18 CLEC12A
C-type lectin domain family 12, member A
7527
0.14
chr3_5019013_5019527 0.18 BHLHE40
basic helix-loop-helix family, member e40
1531
0.38
chr10_126417275_126417426 0.18 FAM53B
family with sequence similarity 53, member B
14189
0.16
chr16_88748267_88748717 0.18 SNAI3-AS1
SNAI3 antisense RNA 1
3049
0.1
chr22_39638272_39638423 0.18 PDGFB
platelet-derived growth factor beta polypeptide
674
0.63
chr20_23064979_23065243 0.17 CD93
CD93 molecule
1866
0.32
chr8_38216839_38216990 0.17 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
21425
0.11
chr11_67036883_67037040 0.17 ADRBK1
adrenergic, beta, receptor kinase 1
3009
0.16
chr15_63798871_63799191 0.17 USP3
ubiquitin specific peptidase 3
2176
0.37
chr22_37542366_37542517 0.16 IL2RB
interleukin 2 receptor, beta
3589
0.14
chr2_197047793_197047944 0.16 STK17B
serine/threonine kinase 17b
6641
0.2
chr11_44326896_44327745 0.16 ALX4
ALX homeobox 4
4396
0.34
chr12_104856651_104856876 0.16 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
5984
0.3
chr2_10169783_10169983 0.15 KLF11
Kruppel-like factor 11
13093
0.13
chr5_169724277_169724686 0.15 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
750
0.71
chr15_40397944_40398095 0.15 BMF
Bcl2 modifying factor
268
0.9
chr21_45341679_45341830 0.15 ENSG00000199598
.
1972
0.29
chr19_8274834_8275489 0.15 CERS4
ceramide synthase 4
643
0.68
chr6_33610158_33610417 0.15 ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
21126
0.13
chr1_158901311_158901684 0.15 PYHIN1
pyrin and HIN domain family, member 1
139
0.97
chr8_38663717_38663929 0.15 TACC1
transforming, acidic coiled-coil containing protein 1
855
0.58
chr7_1550821_1550972 0.15 AC102953.6

1833
0.26
chr17_29644174_29644325 0.15 CTD-2370N5.3

1409
0.29
chr14_75085047_75085411 0.15 LTBP2
latent transforming growth factor beta binding protein 2
5923
0.21
chr1_19253687_19254204 0.15 IFFO2
intermediate filament family orphan 2
15459
0.16
chr14_99699001_99699256 0.15 AL109767.1

30157
0.18
chr17_45814129_45814344 0.15 TBX21
T-box 21
3626
0.18
chr2_43401435_43401586 0.14 ZFP36L2
ZFP36 ring finger protein-like 2
52238
0.14
chr7_105711766_105712098 0.14 SYPL1
synaptophysin-like 1
26376
0.22
chr9_139923953_139924104 0.14 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
1288
0.16
chr10_126916601_126916752 0.14 CTBP2
C-terminal binding protein 2
67046
0.13
chr19_7770859_7771101 0.14 FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
3948
0.11
chr9_71783775_71784020 0.14 TJP2
tight junction protein 2
5184
0.29
chr1_150532769_150532920 0.14 ADAMTSL4-AS1
ADAMTSL4 antisense RNA 1
1125
0.26
chr6_34360722_34361201 0.14 NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
510
0.78
chr22_39493450_39493612 0.14 APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
251
0.88
chr14_22955216_22955367 0.14 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
880
0.4
chrX_153094909_153095060 0.14 PDZD4
PDZ domain containing 4
367
0.75
chrX_110366573_110366760 0.14 PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
361
0.93
chr1_198651611_198651863 0.13 RP11-553K8.5

15547
0.24
chr1_12124202_12124372 0.13 TNFRSF8
tumor necrosis factor receptor superfamily, member 8
760
0.56
chr7_41921705_41921953 0.13 AC005027.3

176896
0.03
chr19_39825870_39826313 0.13 GMFG
glia maturation factor, gamma
554
0.58
chr2_232571958_232572632 0.13 PTMA
prothymosin, alpha
99
0.91
chr22_31886169_31886386 0.13 EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
354
0.81
chr5_909418_909569 0.13 TRIP13
thyroid hormone receptor interactor 13
15736
0.15
chr16_56691251_56692352 0.13 MT1F
metallothionein 1F
54
0.92
chr8_27183780_27184189 0.13 PTK2B
protein tyrosine kinase 2 beta
356
0.89
chr4_2800321_2800472 0.13 SH3BP2
SH3-domain binding protein 2
105
0.97
chr8_95956181_95956332 0.12 TP53INP1
tumor protein p53 inducible nuclear protein 1
3055
0.18
chr17_47840030_47840441 0.12 FAM117A
family with sequence similarity 117, member A
1258
0.41
chr6_41998934_41999085 0.12 ENSG00000206875
.
12757
0.15
chr12_123513254_123513405 0.12 PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
5872
0.15
chr5_126094279_126094440 0.12 ENSG00000252185
.
3250
0.29
chr6_27661627_27662566 0.12 ENSG00000238648
.
62908
0.08
chr12_9911079_9911493 0.12 CD69
CD69 molecule
2211
0.26
chr19_2620958_2621288 0.12 CTC-265F19.2

9263
0.14
chr7_100223660_100223811 0.12 TFR2
transferrin receptor 2
6992
0.09
chr11_122567611_122567762 0.12 ENSG00000239079
.
29333
0.19
chr18_60087506_60087670 0.12 RP11-640A1.3

42225
0.16
chr18_20651331_20651482 0.12 ENSG00000223023
.
46847
0.11
chr15_92392813_92392964 0.12 SLCO3A1
solute carrier organic anion transporter family, member 3A1
4037
0.29
chr12_131272457_131272715 0.11 ENSG00000238822
.
27312
0.17
chr11_117856643_117857627 0.11 IL10RA
interleukin 10 receptor, alpha
26
0.98
chr2_74743098_74743363 0.11 TLX2
T-cell leukemia homeobox 2
1619
0.14
chr1_160680158_160680309 0.11 CD48
CD48 molecule
1360
0.38
chr1_1141210_1141593 0.11 TNFRSF18
tumor necrosis factor receptor superfamily, member 18
341
0.72
chr19_14277944_14278210 0.11 LPHN1
latrophilin 1
5729
0.13
chr9_130319902_130320178 0.11 FAM129B
family with sequence similarity 129, member B
11327
0.17
chr9_123682878_123683088 0.11 TRAF1
TNF receptor-associated factor 1
6133
0.22
chrX_78621891_78622920 0.11 ITM2A
integral membrane protein 2A
451
0.91
chr5_95152547_95152698 0.11 GLRX
glutaredoxin (thioltransferase)
5793
0.16
chr2_8627682_8628105 0.11 AC011747.7

188003
0.03
chrX_39501672_39501823 0.11 ENSG00000263730
.
18723
0.29
chr21_44820304_44820455 0.11 SIK1
salt-inducible kinase 1
26629
0.24
chr1_22463869_22464020 0.11 WNT4
wingless-type MMTV integration site family, member 4
5515
0.23
chr7_50350295_50350528 0.11 IKZF1
IKAROS family zinc finger 1 (Ikaros)
2093
0.45
chr18_77159141_77159292 0.11 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
1106
0.59
chr9_95895594_95896005 0.11 NINJ1
ninjurin 1
771
0.63
chr12_122237162_122237447 0.11 RHOF
ras homolog family member F (in filopodia)
1279
0.39
chr1_155231583_155232074 0.11 SCAMP3
secretory carrier membrane protein 3
222
0.81
chr6_119634064_119634215 0.11 ENSG00000200732
.
14307
0.25
chr14_100770611_100770762 0.11 SLC25A29
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
2092
0.14
chr15_75082884_75083035 0.10 ENSG00000264386
.
1861
0.2
chr18_77161034_77161555 0.10 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
902
0.67
chr17_57515063_57515214 0.10 RP11-567L7.5

34474
0.15
chr6_45345006_45345267 0.10 SUPT3H
suppressor of Ty 3 homolog (S. cerevisiae)
534
0.83
chr17_76771045_76771282 0.10 CYTH1
cytohesin 1
7191
0.19
chr12_48398455_48398676 0.10 COL2A1
collagen, type II, alpha 1
296
0.86
chr16_68390170_68390671 0.10 SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
14488
0.11
chr7_1051859_1052010 0.10 ENSG00000199023
.
10728
0.1
chr3_128523693_128523920 0.10 RAB7A
RAB7A, member RAS oncogene family
9604
0.18
chr9_132222026_132222209 0.10 ENSG00000264298
.
18718
0.2
chr6_167507024_167507239 0.10 CCR6
chemokine (C-C motif) receptor 6
18164
0.18
chr3_71478867_71479018 0.10 ENSG00000221264
.
112298
0.06
chr17_80063977_80064793 0.10 CCDC57
coiled-coil domain containing 57
4659
0.1
chr9_134113693_134114226 0.10 NUP214
nucleoporin 214kDa
10278
0.17
chr17_48217501_48218008 0.10 AC002401.1

4803
0.11
chr22_25960035_25960186 0.10 CTA-407F11.8

7
0.93
chr2_143885996_143886303 0.10 ARHGAP15
Rho GTPase activating protein 15
734
0.76
chr1_47048198_47048369 0.10 MKNK1
MAP kinase interacting serine/threonine kinase 1
2949
0.2
chr12_12867727_12867916 0.10 CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
2237
0.23
chr3_183852600_183853095 0.10 RP11-778D9.12

122
0.61
chr22_44578201_44578448 0.10 PARVG
parvin, gamma
583
0.83
chr17_80229441_80229710 0.10 CSNK1D
casein kinase 1, delta
1729
0.23
chr3_14241386_14241537 0.10 XPC
xeroderma pigmentosum, complementation group C
21178
0.17
chr13_37574524_37574865 0.10 EXOSC8
exosome component 8
16
0.96
chr3_128734717_128734917 0.10 EFCC1
EF-hand and coiled-coil domain containing 1
14345
0.13
chr5_156700321_156700472 0.10 CYFIP2
cytoplasmic FMR1 interacting protein 2
4034
0.17
chr8_134071502_134071774 0.10 SLA
Src-like-adaptor
965
0.65
chr22_38036611_38036887 0.10 SH3BP1
SH3-domain binding protein 1
722
0.49
chr2_233925739_233925978 0.10 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
669
0.7
chr9_5832277_5833455 0.10 ERMP1
endoplasmic reticulum metallopeptidase 1
251
0.93
chr10_25176560_25176711 0.09 ENSG00000240294
.
21106
0.23
chr10_106083582_106083733 0.09 ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
5025
0.15
chr1_154379631_154380335 0.09 RP11-350G8.5

943
0.42
chr2_204572488_204572658 0.09 CD28
CD28 molecule
1157
0.58
chr20_57266602_57266883 0.09 NPEPL1
aminopeptidase-like 1
927
0.53
chr9_130546021_130546292 0.09 CDK9
cyclin-dependent kinase 9
1802
0.16
chr1_44873108_44873259 0.09 RNF220
ring finger protein 220
2223
0.29
chr7_154997328_154997479 0.09 AC099552.4
Uncharacterized protein
7257
0.22
chr14_23341701_23341904 0.09 LRP10
low density lipoprotein receptor-related protein 10
289
0.77
chr17_9549466_9549768 0.09 USP43
ubiquitin specific peptidase 43
763
0.39
chr14_35303482_35303633 0.09 ENSG00000251726
.
11009
0.17
chr16_70286070_70286221 0.09 EXOSC6
exosome component 6
312
0.77
chr13_91827106_91827257 0.09 ENSG00000215417
.
175678
0.04
chr12_68775706_68775857 0.09 MDM1
Mdm1 nuclear protein homolog (mouse)
49620
0.17
chr11_112096740_112097015 0.09 PTS
6-pyruvoyltetrahydropterin synthase
211
0.89
chr1_12244133_12244323 0.09 ENSG00000263676
.
7542
0.16
chrX_23872431_23872582 0.09 APOO
apolipoprotein O
26512
0.15
chr3_112323750_112323901 0.09 CCDC80
coiled-coil domain containing 80
5302
0.24
chr7_102044904_102045055 0.09 ENSG00000221510
.
1323
0.27
chr2_85806418_85806569 0.09 VAMP8
vesicle-associated membrane protein 8
1777
0.17
chr13_78272907_78273541 0.09 SLAIN1
SLAIN motif family, member 1
207
0.89
chr8_131020590_131020791 0.09 ENSG00000264653
.
9
0.97
chr9_140171799_140172072 0.09 TOR4A
torsin family 4, member A
266
0.79
chr9_92786212_92786363 0.09 ENSG00000263967
.
470
0.9
chr2_241390296_241390447 0.09 GPC1
glypican 1
1857
0.28
chr1_226920663_226921046 0.09 ITPKB
inositol-trisphosphate 3-kinase B
4305
0.27
chr4_75263884_75264078 0.09 EREG
epiregulin
33121
0.14
chr10_90754998_90755312 0.09 ACTA2
actin, alpha 2, smooth muscle, aorta
4008
0.17
chr16_31411645_31411796 0.09 RP11-120K18.2

2166
0.18
chr6_15245727_15246152 0.09 JARID2
jumonji, AT rich interactive domain 2
588
0.74
chr3_13462664_13462815 0.09 NUP210
nucleoporin 210kDa
930
0.65
chr22_22293537_22293770 0.08 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
697
0.45
chr9_139929070_139929505 0.08 FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
1825
0.11
chr9_79265748_79266757 0.08 PRUNE2
prune homolog 2 (Drosophila)
1213
0.53
chr3_71751711_71751862 0.08 EIF4E3
eukaryotic translation initiation factor 4E family member 3
22740
0.2
chr22_20225722_20225873 0.08 RTN4R
reticulon 4 receptor
5410
0.14
chr2_233179871_233180040 0.08 DIS3L2
DIS3 mitotic control homolog (S. cerevisiae)-like 2
18698
0.17
chr18_72166510_72167447 0.08 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
118
0.97
chr1_111174065_111174216 0.08 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
44
0.98
chr17_38769482_38769633 0.08 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
18985
0.13
chr12_124950039_124950191 0.08 NCOR2
nuclear receptor corepressor 2
18200
0.28
chr11_67857787_67857938 0.08 CHKA
choline kinase alpha
30433
0.1
chr12_122239467_122240363 0.08 RHOF
ras homolog family member F (in filopodia)
919
0.49
chr17_75450826_75450977 0.08 SEPT9
septin 9
739
0.6
chr10_53458598_53459393 0.08 CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
360
0.92
chr2_144941449_144941842 0.08 GTDC1
glycosyltransferase-like domain containing 1
51659
0.18
chr1_19805004_19805155 0.08 CAPZB
capping protein (actin filament) muscle Z-line, beta
5500
0.18
chr1_200989934_200990087 0.08 KIF21B
kinesin family member 21B
2526
0.27
chr17_36860259_36860862 0.08 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
1235
0.2
chr19_41857713_41858218 0.08 TMEM91
transmembrane protein 91
1149
0.27

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of SREBF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions