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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for STAT5A

Z-value: 1.98

Motif logo

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
ENSG00000126561.12 STAT5A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
STAT5Achr17_40465551_4046570274380.1339860.713.1e-02Click!
STAT5Achr17_40481329_40481480232160.111660-0.674.9e-02Click!
STAT5Achr17_40482001_40482152238880.110637-0.675.0e-02Click!
STAT5Achr17_40489823_40489974317100.097812-0.637.0e-02Click!
STAT5Achr17_40441173_404413957230.5445380.561.2e-01Click!

Activity of the STAT5A motif across conditions

Conditions sorted by the z-value of the STAT5A motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_6103670_6104125 2.15 IL2RA
interleukin 2 receptor, alpha
356
0.84
chr1_209943452_209943666 1.67 TRAF3IP3
TRAF3 interacting protein 3
1599
0.29
chr5_156621256_156621554 1.37 ITK
IL2-inducible T-cell kinase
13568
0.12
chr18_9084010_9084262 1.28 NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
18492
0.17
chrX_9250795_9250946 1.19 ENSG00000200852
.
149001
0.04
chr8_134086172_134086360 1.12 SLA
Src-like-adaptor
13663
0.23
chr20_35575234_35575857 1.11 SAMHD1
SAM domain and HD domain 1
4566
0.25
chr4_78738053_78738204 1.08 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
2089
0.42
chr3_111261315_111261845 1.02 CD96
CD96 molecule
583
0.82
chr1_32718292_32718517 0.95 LCK
lymphocyte-specific protein tyrosine kinase
1529
0.2
chr13_41556163_41556400 0.94 ELF1
E74-like factor 1 (ets domain transcription factor)
137
0.96
chr6_108144289_108144729 0.94 SCML4
sex comb on midleg-like 4 (Drosophila)
1007
0.66
chr6_37017654_37018643 0.93 COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
5541
0.22
chr15_81590554_81590826 0.92 IL16
interleukin 16
1067
0.54
chr17_4617872_4618023 0.92 ARRB2
arrestin, beta 2
937
0.33
chr14_22971834_22972057 0.91 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
15774
0.09
chr1_160616059_160616370 0.91 SLAMF1
signaling lymphocytic activation molecule family member 1
597
0.7
chr2_12085875_12086062 0.91 ENSG00000238503
.
84530
0.09
chr8_61880060_61880353 0.91 CLVS1
clavesin 1
89511
0.1
chr7_150414088_150414577 0.91 GIMAP1
GTPase, IMAP family member 1
687
0.65
chr2_175498427_175499207 0.91 WIPF1
WAS/WASL interacting protein family, member 1
490
0.83
chr4_40232301_40232591 0.89 RHOH
ras homolog family member H
30482
0.18
chr7_50267269_50267784 0.88 IKZF1
IKAROS family zinc finger 1 (Ikaros)
76798
0.1
chr22_40298890_40299260 0.88 GRAP2
GRB2-related adaptor protein 2
1962
0.3
chrX_78201853_78202096 0.88 P2RY10
purinergic receptor P2Y, G-protein coupled, 10
1056
0.69
chr1_206732914_206733127 0.87 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
2527
0.25
chr6_154567391_154567649 0.87 IPCEF1
interaction protein for cytohesin exchange factors 1
470
0.9
chr10_105670292_105670878 0.86 OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
6842
0.18
chr9_101881133_101881552 0.84 TGFBR1
transforming growth factor, beta receptor 1
8715
0.21
chr1_111417492_111418003 0.84 CD53
CD53 molecule
1971
0.34
chr18_29598595_29599964 0.83 RNF125
ring finger protein 125, E3 ubiquitin protein ligase
944
0.53
chr12_47609896_47610314 0.83 PCED1B
PC-esterase domain containing 1B
53
0.98
chr17_56410837_56411117 0.83 MIR142
microRNA 142
1108
0.32
chr14_22994691_22994955 0.83 TRAJ15
T cell receptor alpha joining 15
3757
0.14
chr2_237446290_237446506 0.82 ACKR3
atypical chemokine receptor 3
30032
0.19
chr5_130589485_130589693 0.82 CDC42SE2
CDC42 small effector 2
10113
0.28
chr3_183271904_183272141 0.82 KLHL6
kelch-like family member 6
1455
0.38
chr17_19031223_19031746 0.81 GRAPL
GRB2-related adaptor protein-like
636
0.51
chr3_108544304_108544541 0.81 TRAT1
T cell receptor associated transmembrane adaptor 1
2803
0.36
chr1_151129106_151129618 0.80 SCNM1
sodium channel modifier 1
222
0.51
chr7_150212658_150212835 0.80 GIMAP7
GTPase, IMAP family member 7
828
0.63
chr9_95716277_95716712 0.79 FGD3
FYVE, RhoGEF and PH domain containing 3
6761
0.23
chr6_154566868_154567140 0.79 IPCEF1
interaction protein for cytohesin exchange factors 1
986
0.71
chr6_158401409_158401560 0.78 SYNJ2
synaptojanin 2
1404
0.42
chr2_86078996_86079261 0.78 ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
15649
0.16
chr1_89740013_89740507 0.77 GBP5
guanylate binding protein 5
1716
0.37
chr1_169650096_169650247 0.77 SELL
selectin L
30668
0.16
chr9_117692323_117692779 0.77 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
146
0.98
chr14_22466139_22466361 0.77 ENSG00000238634
.
144637
0.04
chr3_56950038_56950370 0.76 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
295
0.93
chr5_130602420_130602583 0.76 CDC42SE2
CDC42 small effector 2
2708
0.39
chr17_265803_266293 0.75 AC108004.3

2234
0.23
chr12_47606694_47606931 0.74 PCED1B
PC-esterase domain containing 1B
3240
0.28
chr17_18949799_18949950 0.74 GRAP
GRB2-related adaptor protein
436
0.73
chrX_78402769_78403059 0.74 GPR174
G protein-coupled receptor 174
23555
0.28
chr17_29641266_29641417 0.74 EVI2B
ecotropic viral integration site 2B
211
0.9
chr2_8597006_8597252 0.73 AC011747.7

218767
0.02
chr3_4872241_4872810 0.73 ENSG00000239126
.
47861
0.15
chr3_18484268_18484419 0.73 SATB1
SATB homeobox 1
2022
0.31
chr8_29356447_29357119 0.72 RP4-676L2.1

146096
0.04
chr12_122096565_122097046 0.72 MORN3
MORN repeat containing 3
10755
0.18
chr14_93120741_93121126 0.72 RIN3
Ras and Rab interactor 3
2087
0.42
chr3_63965361_63965766 0.72 ATXN7
ataxin 7
12143
0.14
chr12_56415111_56415360 0.72 IKZF4
IKAROS family zinc finger 4 (Eos)
135
0.91
chr7_150328400_150328619 0.71 GIMAP6
GTPase, IMAP family member 6
925
0.59
chrX_78404824_78405114 0.71 GPR174
G protein-coupled receptor 174
21500
0.29
chr7_106766845_106767175 0.71 CTA-360L10.1

7168
0.23
chr15_86234321_86234539 0.71 RP11-815J21.1

9910
0.12
chr14_25143375_25143614 0.70 GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
40021
0.14
chr14_22937868_22938019 0.70 TRAJ60
T cell receptor alpha joining 60 (pseudogene)
7353
0.1
chr14_98442707_98443118 0.70 C14orf64
chromosome 14 open reading frame 64
1471
0.59
chr16_27415358_27415584 0.70 IL21R
interleukin 21 receptor
1048
0.56
chr17_2699201_2699651 0.70 RAP1GAP2
RAP1 GTPase activating protein 2
306
0.89
chr2_237446083_237446280 0.70 IQCA1
IQ motif containing with AAA domain 1
29996
0.19
chr13_75899167_75899318 0.69 TBC1D4
TBC1 domain family, member 4
16425
0.24
chr16_11145985_11146136 0.69 RP11-66H6.3

18899
0.19
chr1_175162248_175162570 0.69 KIAA0040
KIAA0040
330
0.93
chr7_150382525_150383418 0.69 GIMAP2
GTPase, IMAP family member 2
156
0.95
chr10_8179462_8179700 0.69 GATA3
GATA binding protein 3
82812
0.11
chr2_175460295_175460493 0.68 WIPF1
WAS/WASL interacting protein family, member 1
2099
0.3
chr16_79123602_79124194 0.68 RP11-556H2.3

49
0.98
chr6_133067698_133067849 0.67 RP1-55C23.7

6041
0.13
chrX_77582442_77582995 0.67 CYSLTR1
cysteinyl leukotriene receptor 1
262
0.96
chr4_109028345_109028496 0.67 LEF1
lymphoid enhancer-binding factor 1
59037
0.12
chr1_198621955_198622106 0.67 PTPRC
protein tyrosine phosphatase, receptor type, C
13738
0.23
chr15_59344480_59344631 0.67 RNF111
ring finger protein 111
20732
0.16
chr12_109026699_109026850 0.67 SELPLG
selectin P ligand
896
0.46
chr19_44809165_44809335 0.67 ZNF235
zinc finger protein 235
51
0.97
chr9_134150778_134151758 0.67 FAM78A
family with sequence similarity 78, member A
666
0.69
chr9_100667597_100668036 0.66 C9orf156
chromosome 9 open reading frame 156
6937
0.17
chr1_24830928_24831111 0.66 RCAN3
RCAN family member 3
1632
0.35
chr5_118623311_118623849 0.66 ENSG00000243333
.
18746
0.17
chr9_123684795_123684946 0.65 TRAF1
TNF receptor-associated factor 1
6177
0.23
chr17_64327814_64327965 0.65 PRKCA
protein kinase C, alpha
28945
0.16
chr3_13462158_13462340 0.65 NUP210
nucleoporin 210kDa
440
0.87
chr1_236051645_236051799 0.65 LYST
lysosomal trafficking regulator
4850
0.19
chr2_237446743_237446920 0.65 ACKR3
atypical chemokine receptor 3
29599
0.19
chr20_62271866_62272113 0.65 STMN3
stathmin-like 3
12130
0.09
chr6_31544266_31544562 0.65 TNF
tumor necrosis factor
1070
0.2
chr17_76123581_76124282 0.65 TMC6
transmembrane channel-like 6
780
0.49
chr14_22982783_22983297 0.65 TRAJ15
T cell receptor alpha joining 15
15540
0.1
chr9_274688_274839 0.64 DOCK8
dedicator of cytokinesis 8
1693
0.31
chr3_18479661_18479848 0.64 SATB1
SATB homeobox 1
430
0.85
chr2_112939934_112940174 0.64 FBLN7
fibulin 7
594
0.8
chr11_118755543_118755694 0.64 CXCR5
chemokine (C-X-C motif) receptor 5
1143
0.3
chr1_167601517_167601668 0.64 RP3-455J7.4

1681
0.33
chr3_151961203_151961354 0.64 MBNL1
muscleblind-like splicing regulator 1
24551
0.2
chr10_30993847_30994006 0.64 SVILP1
supervillin pseudogene 1
9076
0.27
chr17_28134983_28135134 0.64 ENSG00000252657
.
30421
0.12
chr7_142344805_142344957 0.64 MTRNR2L6
MT-RNR2-like 6
29223
0.21
chr10_14611757_14612021 0.63 FAM107B
family with sequence similarity 107, member B
2140
0.39
chr7_623467_623815 0.63 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
18679
0.14
chr19_2562041_2562223 0.63 CTC-265F19.2

49728
0.09
chr2_237445797_237446029 0.63 IQCA1
IQ motif containing with AAA domain 1
29728
0.19
chr2_85534473_85534624 0.63 ENSG00000221579
.
8391
0.11
chr12_57872273_57872424 0.63 ARHGAP9
Rho GTPase activating protein 9
45
0.94
chr16_3125184_3125385 0.63 ENSG00000252561
.
5760
0.06
chr2_172175996_172176199 0.63 METTL8
methyltransferase like 8
19669
0.24
chr18_63017285_63017436 0.62 CDH7
cadherin 7, type 2
400128
0.01
chr4_7761238_7761507 0.62 AFAP1-AS1
AFAP1 antisense RNA 1
5555
0.25
chr14_22938092_22938243 0.62 TRAJ60
T cell receptor alpha joining 60 (pseudogene)
7129
0.11
chr2_198172874_198173132 0.62 ANKRD44
ankyrin repeat domain 44
2508
0.23
chr12_6554914_6555065 0.62 CD27
CD27 molecule
956
0.36
chr1_31223372_31223523 0.62 LAPTM5
lysosomal protein transmembrane 5
7220
0.16
chr17_29638804_29639264 0.62 EVI2B
ecotropic viral integration site 2B
2068
0.22
chr22_37562830_37562981 0.62 RP1-151B14.6

108
0.94
chr3_172235814_172236037 0.61 TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
5340
0.27
chr3_71773124_71773375 0.61 EIF4E3
eukaryotic translation initiation factor 4E family member 3
1277
0.5
chr9_117147390_117147560 0.61 AKNA
AT-hook transcription factor
2768
0.28
chr18_67623845_67624178 0.61 CD226
CD226 molecule
105
0.98
chr12_6899553_6899934 0.61 CD4
CD4 molecule
1009
0.28
chr22_17567534_17567787 0.61 IL17RA
interleukin 17 receptor A
1811
0.31
chr18_13383808_13383959 0.61 LDLRAD4
low density lipoprotein receptor class A domain containing 4
1330
0.39
chr2_237447196_237447364 0.61 ACKR3
atypical chemokine receptor 3
29150
0.19
chr1_31227757_31227908 0.60 LAPTM5
lysosomal protein transmembrane 5
2835
0.23
chr10_81678709_81678860 0.60 SFTPD
surfactant protein D
30075
0.2
chr2_204570249_204570400 0.60 CD28
CD28 molecule
874
0.69
chr19_17516551_17516849 0.60 MVB12A
multivesicular body subunit 12A
150
0.6
chr17_11040783_11040934 0.60 ENSG00000243346
.
19914
0.24
chr2_10470298_10470561 0.60 HPCAL1
hippocalcin-like 1
26603
0.16
chr1_78392239_78392485 0.60 NEXN
nexilin (F actin binding protein)
8549
0.18
chr8_82021757_82021939 0.60 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
2455
0.41
chr6_209495_209646 0.59 DUSP22
dual specificity phosphatase 22
82060
0.11
chr13_31311572_31311749 0.59 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
2015
0.45
chr11_118087227_118087423 0.59 AMICA1
adhesion molecule, interacts with CXADR antigen 1
1719
0.29
chr4_40211899_40212136 0.59 RHOH
ras homolog family member H
10053
0.22
chr13_49065972_49066123 0.59 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
41166
0.17
chr17_78237440_78238417 0.59 RNF213
ring finger protein 213
3259
0.2
chr22_31336224_31336733 0.59 MORC2
MORC family CW-type zinc finger 2
7597
0.16
chrX_48776392_48776920 0.59 PIM2
pim-2 oncogene
355
0.76
chr20_57735286_57735495 0.59 ZNF831
zinc finger protein 831
30685
0.19
chr13_42033292_42033443 0.59 RGCC
regulator of cell cycle
1672
0.31
chr17_266453_266873 0.59 AC108004.3

2849
0.2
chr9_101899616_101899767 0.58 ENSG00000252942
.
8557
0.19
chr17_41393290_41393559 0.58 ENSG00000236383
.
10086
0.14
chr11_2466894_2467127 0.58 KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
789
0.56
chr1_100887352_100887656 0.58 ENSG00000216067
.
43173
0.14
chr1_108505703_108505854 0.58 VAV3-AS1
VAV3 antisense RNA 1
1287
0.41
chr5_118607055_118607314 0.58 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
2735
0.27
chr22_30617296_30617447 0.58 RP3-438O4.4

14273
0.11
chr2_197065721_197065922 0.58 ENSG00000239161
.
14225
0.18
chr3_16330036_16330187 0.58 OXNAD1
oxidoreductase NAD-binding domain containing 1
19363
0.15
chr1_101705566_101705834 0.58 RP4-575N6.5

3014
0.19
chr16_27413508_27414237 0.58 IL21R
interleukin 21 receptor
377
0.88
chr7_1979810_1980119 0.58 MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
221
0.96
chr14_98442268_98442419 0.57 C14orf64
chromosome 14 open reading frame 64
2040
0.5
chr20_37435342_37435890 0.57 PPP1R16B
protein phosphatase 1, regulatory subunit 16B
1249
0.47
chr7_6065967_6066118 0.57 EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
141
0.91
chr2_158292414_158292565 0.57 CYTIP
cytohesin 1 interacting protein
3437
0.27
chr8_37751638_37751789 0.57 RAB11FIP1
RAB11 family interacting protein 1 (class I)
5259
0.15
chrY_15016234_15016524 0.57 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
350
0.93
chr21_36410157_36410308 0.57 RUNX1
runt-related transcription factor 1
11230
0.32
chr5_118609514_118610204 0.57 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
5410
0.21
chr5_35859258_35859647 0.57 IL7R
interleukin 7 receptor
2458
0.3
chr4_154443549_154443747 0.56 KIAA0922
KIAA0922
33400
0.2
chr14_99733165_99733625 0.56 AL109767.1

4110
0.24
chr19_47689837_47689988 0.56 ENSG00000265134
.
40287
0.1
chr11_95420136_95420287 0.56 FAM76B
family with sequence similarity 76, member B
99758
0.08
chr10_30707556_30707739 0.56 MAP3K8
mitogen-activated protein kinase kinase kinase 8
15219
0.19
chr20_37501287_37501438 0.56 ENSG00000240474
.
51
0.98
chr12_92532725_92532888 0.56 C12orf79
chromosome 12 open reading frame 79
2009
0.29
chr16_29677209_29677502 0.56 QPRT
quinolinate phosphoribosyltransferase
2755
0.17
chr2_240219542_240220118 0.55 ENSG00000265215
.
7327
0.19
chr21_46346446_46346882 0.55 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
1969
0.18
chr5_137416910_137417200 0.55 WNT8A
wingless-type MMTV integration site family, member 8A
2526
0.17
chr2_223290336_223290619 0.55 SGPP2
sphingosine-1-phosphate phosphatase 2
1241
0.5
chr3_108541565_108541773 0.55 TRAT1
T cell receptor associated transmembrane adaptor 1
50
0.98
chr6_25136833_25137456 0.55 ENSG00000222373
.
55497
0.11
chr13_31312414_31312565 0.55 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
2844
0.37
chr10_29769061_29769212 0.55 SVIL
supervillin
16311
0.22
chr11_108724912_108725630 0.55 ENSG00000201243
.
150973
0.04
chr10_11221601_11222262 0.55 RP3-323N1.2

8592
0.22
chr3_187455559_187456689 0.55 BCL6
B-cell CLL/lymphoma 6
392
0.87
chr7_150436038_150436258 0.55 GIMAP5
GTPase, IMAP family member 5
1712
0.32
chr15_57199386_57199736 0.55 ZNF280D
zinc finger protein 280D
11208
0.22
chrX_40029862_40030013 0.55 BCOR
BCL6 corepressor
6636
0.32
chr1_111215065_111215351 0.55 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
2447
0.28
chr3_13053634_13053814 0.54 IQSEC1
IQ motif and Sec7 domain 1
25188
0.24
chr4_38511545_38511706 0.54 RP11-617D20.1

114571
0.06
chr17_33863414_33863594 0.54 SLFN12L
schlafen family member 12-like
1376
0.29

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of STAT5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.4 1.5 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3 1.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 0.9 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.2 1.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 0.6 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.2 0.4 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.2 0.6 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 0.8 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.2 1.0 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.2 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 1.0 GO:0002363 alpha-beta T cell lineage commitment(GO:0002363)
0.2 0.6 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.2 0.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.5 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.2 1.4 GO:0015671 oxygen transport(GO:0015671)
0.2 0.5 GO:0070295 renal water absorption(GO:0070295)
0.2 1.8 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.2 0.6 GO:0000089 mitotic metaphase(GO:0000089)
0.2 0.3 GO:0010535 regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.2 0.5 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 0.6 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.6 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 1.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.6 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.3 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.4 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.1 GO:0046643 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0002836 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1 0.5 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.3 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1 0.5 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.1 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:0002664 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1 0.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.9 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.1 0.3 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.3 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.1 0.2 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.3 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.2 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.1 GO:0032663 regulation of interleukin-2 production(GO:0032663) negative regulation of interleukin-2 production(GO:0032703)
0.1 1.2 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.3 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.2 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032)
0.1 1.0 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.2 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.3 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 1.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1 0.4 GO:0048535 lymph node development(GO:0048535)
0.1 0.4 GO:0001782 B cell homeostasis(GO:0001782)
0.1 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.9 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.2 GO:0003170 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.1 0.2 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.2 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.1 0.3 GO:0006991 response to sterol depletion(GO:0006991)
0.1 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.2 GO:0045576 mast cell activation(GO:0045576)
0.1 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.2 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.1 0.1 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.2 GO:0048478 replication fork protection(GO:0048478)
0.1 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 0.1 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.2 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.3 GO:0034311 diol metabolic process(GO:0034311)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0061046 regulation of branching involved in lung morphogenesis(GO:0061046)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0015809 arginine transport(GO:0015809)
0.0 0.3 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.2 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.3 GO:0042267 natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.2 GO:0032352 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0002820 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.2 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.5 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.9 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0032613 interleukin-10 production(GO:0032613)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0048242 epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0 0.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.3 GO:0051322 anaphase(GO:0051322)
0.0 0.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0071223 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.0 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 1.1 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.0 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.5 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.6 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:0070897 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.6 GO:0006997 nucleus organization(GO:0006997)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.2 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.1 GO:0097194 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.0 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.6 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0009264 deoxyribonucleotide catabolic process(GO:0009264)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.0 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0010039 response to iron ion(GO:0010039)
0.0 0.0 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.1 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.3 GO:0031280 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.1 GO:0016445 somatic diversification of immune receptors(GO:0002200) somatic diversification of immunoglobulins(GO:0016445)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.3 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.1 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.0 GO:0034444 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0071222 cellular response to lipopolysaccharide(GO:0071222)
0.0 0.6 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.0 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.0 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.1 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.0 GO:0071622 regulation of granulocyte chemotaxis(GO:0071622)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.3 GO:0007632 visual behavior(GO:0007632)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.0 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.4 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0019048 modulation by virus of host morphology or physiology(GO:0019048)
0.0 0.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.0 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0060761 negative regulation of response to cytokine stimulus(GO:0060761)
0.0 0.1 GO:0051187 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) cofactor catabolic process(GO:0051187)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.4 GO:0006909 phagocytosis(GO:0006909)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0051299 centrosome separation(GO:0051299)
0.0 0.0 GO:0032769 negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.0 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.1 GO:0042516 tyrosine phosphorylation of Stat3 protein(GO:0042503) regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0043954 cellular component maintenance(GO:0043954)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.3 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:1904590 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.0 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:1902932 positive regulation of alcohol biosynthetic process(GO:1902932)
0.0 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0015992 proton transport(GO:0015992)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.6 GO:0061025 membrane fusion(GO:0061025)
0.0 0.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.0 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.6 GO:0000236 mitotic prometaphase(GO:0000236)
0.0 0.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.0 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.6 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 4.8 GO:0006955 immune response(GO:0006955)
0.0 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.0 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.0 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.0 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.0 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.0 GO:0048011 neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0008306 associative learning(GO:0008306)
0.0 0.2 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0044036 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.0 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:1902743 regulation of lamellipodium organization(GO:1902743)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 1.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.0 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.2 GO:0042629 mast cell granule(GO:0042629)
0.1 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.3 GO:0000800 lateral element(GO:0000800)
0.1 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:0001739 sex chromatin(GO:0001739)
0.1 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.2 GO:0005638 lamin filament(GO:0005638)
0.1 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.0 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 4.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.5 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.0 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0051233 spindle midzone(GO:0051233)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0035097 methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.0 GO:0030897 HOPS complex(GO:0030897)
0.0 0.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 1.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.8 GO:0005769 early endosome(GO:0005769)
0.0 0.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.3 1.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 1.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.2 0.9 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.2 0.9 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.0 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.5 GO:0004904 interferon receptor activity(GO:0004904)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.3 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.9 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.7 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.1 GO:0001846 opsonin binding(GO:0001846)
0.1 0.6 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.9 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.7 GO:0003823 antigen binding(GO:0003823)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.1 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0016801 hydrolase activity, acting on ether bonds(GO:0016801)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0045502 dynein binding(GO:0045502)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0042287 MHC protein binding(GO:0042287) MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.0 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.6 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.6 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0051540 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.6 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 3.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.0 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 2.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 7.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 0.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID ATM PATHWAY ATM pathway
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 2.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.1 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 0.8 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.3 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling