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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for STAT5A

Z-value: 1.98

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Transcription factors associated with STAT5A

Gene Symbol	Gene ID	Gene Info
STAT5A Ensembl NCBI GeneCards UniProt	ENSG00000126561.12	signal transducer and activator of transcription 5A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_40465551_40465702	STAT5A	7438	0.133986	0.71	3.1e-02	Click!
chr17_40481329_40481480	STAT5A	23216	0.111660	-0.67	4.9e-02	Click!
chr17_40482001_40482152	STAT5A	23888	0.110637	-0.67	5.0e-02	Click!
chr17_40489823_40489974	STAT5A	31710	0.097812	-0.63	7.0e-02	Click!
chr17_40441173_40441395	STAT5A	723	0.544538	0.56	1.2e-01	Click!

Activity of the STAT5A motif across conditions

Conditions sorted by the z-value of the STAT5A motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_6103670_6104125	2.15	IL2RA	interleukin 2 receptor, alpha	356	0.84
chr1_209943452_209943666	1.67	TRAF3IP3	TRAF3 interacting protein 3	1599	0.29
chr5_156621256_156621554	1.37	ITK	IL2-inducible T-cell kinase	13568	0.12
chr18_9084010_9084262	1.28	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	18492	0.17
chrX_9250795_9250946	1.19	ENSG00000200852	.	149001	0.04
chr8_134086172_134086360	1.12	SLA	Src-like-adaptor	13663	0.23
chr20_35575234_35575857	1.11	SAMHD1	SAM domain and HD domain 1	4566	0.25
chr4_78738053_78738204	1.08	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	2089	0.42
chr3_111261315_111261845	1.02	CD96	CD96 molecule	583	0.82
chr1_32718292_32718517	0.95	LCK	lymphocyte-specific protein tyrosine kinase	1529	0.2
chr13_41556163_41556400	0.94	ELF1	E74-like factor 1 (ets domain transcription factor)	137	0.96
chr6_108144289_108144729	0.94	SCML4	sex comb on midleg-like 4 (Drosophila)	1007	0.66
chr6_37017654_37018643	0.93	COX6A1P2	cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2	5541	0.22
chr15_81590554_81590826	0.92	IL16	interleukin 16	1067	0.54
chr17_4617872_4618023	0.92	ARRB2	arrestin, beta 2	937	0.33
chr14_22971834_22972057	0.91	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	15774	0.09
chr1_160616059_160616370	0.91	SLAMF1	signaling lymphocytic activation molecule family member 1	597	0.7
chr2_12085875_12086062	0.91	ENSG00000238503	.	84530	0.09
chr8_61880060_61880353	0.91	CLVS1	clavesin 1	89511	0.1
chr7_150414088_150414577	0.91	GIMAP1	GTPase, IMAP family member 1	687	0.65
chr2_175498427_175499207	0.91	WIPF1	WAS/WASL interacting protein family, member 1	490	0.83
chr4_40232301_40232591	0.89	RHOH	ras homolog family member H	30482	0.18
chr7_50267269_50267784	0.88	IKZF1	IKAROS family zinc finger 1 (Ikaros)	76798	0.1
chr22_40298890_40299260	0.88	GRAP2	GRB2-related adaptor protein 2	1962	0.3
chrX_78201853_78202096	0.88	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	1056	0.69
chr1_206732914_206733127	0.87	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	2527	0.25
chr6_154567391_154567649	0.87	IPCEF1	interaction protein for cytohesin exchange factors 1	470	0.9
chr10_105670292_105670878	0.86	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	6842	0.18
chr9_101881133_101881552	0.84	TGFBR1	transforming growth factor, beta receptor 1	8715	0.21
chr1_111417492_111418003	0.84	CD53	CD53 molecule	1971	0.34
chr18_29598595_29599964	0.83	RNF125	ring finger protein 125, E3 ubiquitin protein ligase	944	0.53
chr12_47609896_47610314	0.83	PCED1B	PC-esterase domain containing 1B	53	0.98
chr17_56410837_56411117	0.83	MIR142	microRNA 142	1108	0.32
chr14_22994691_22994955	0.83	TRAJ15	T cell receptor alpha joining 15	3757	0.14
chr2_237446290_237446506	0.82	ACKR3	atypical chemokine receptor 3	30032	0.19
chr5_130589485_130589693	0.82	CDC42SE2	CDC42 small effector 2	10113	0.28
chr3_183271904_183272141	0.82	KLHL6	kelch-like family member 6	1455	0.38
chr17_19031223_19031746	0.81	GRAPL	GRB2-related adaptor protein-like	636	0.51
chr3_108544304_108544541	0.81	TRAT1	T cell receptor associated transmembrane adaptor 1	2803	0.36
chr1_151129106_151129618	0.80	SCNM1	sodium channel modifier 1	222	0.51
chr7_150212658_150212835	0.80	GIMAP7	GTPase, IMAP family member 7	828	0.63
chr9_95716277_95716712	0.79	FGD3	FYVE, RhoGEF and PH domain containing 3	6761	0.23
chr6_154566868_154567140	0.79	IPCEF1	interaction protein for cytohesin exchange factors 1	986	0.71
chr6_158401409_158401560	0.78	SYNJ2	synaptojanin 2	1404	0.42
chr2_86078996_86079261	0.78	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	15649	0.16
chr1_89740013_89740507	0.77	GBP5	guanylate binding protein 5	1716	0.37
chr1_169650096_169650247	0.77	SELL	selectin L	30668	0.16
chr9_117692323_117692779	0.77	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	146	0.98
chr14_22466139_22466361	0.77	ENSG00000238634	.	144637	0.04
chr3_56950038_56950370	0.76	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	295	0.93
chr5_130602420_130602583	0.76	CDC42SE2	CDC42 small effector 2	2708	0.39
chr17_265803_266293	0.75	AC108004.3		2234	0.23
chr12_47606694_47606931	0.74	PCED1B	PC-esterase domain containing 1B	3240	0.28
chr17_18949799_18949950	0.74	GRAP	GRB2-related adaptor protein	436	0.73
chrX_78402769_78403059	0.74	GPR174	G protein-coupled receptor 174	23555	0.28
chr17_29641266_29641417	0.74	EVI2B	ecotropic viral integration site 2B	211	0.9
chr2_8597006_8597252	0.73	AC011747.7		218767	0.02
chr3_4872241_4872810	0.73	ENSG00000239126	.	47861	0.15
chr3_18484268_18484419	0.73	SATB1	SATB homeobox 1	2022	0.31
chr8_29356447_29357119	0.72	RP4-676L2.1		146096	0.04
chr12_122096565_122097046	0.72	MORN3	MORN repeat containing 3	10755	0.18
chr14_93120741_93121126	0.72	RIN3	Ras and Rab interactor 3	2087	0.42
chr3_63965361_63965766	0.72	ATXN7	ataxin 7	12143	0.14
chr12_56415111_56415360	0.72	IKZF4	IKAROS family zinc finger 4 (Eos)	135	0.91
chr7_150328400_150328619	0.71	GIMAP6	GTPase, IMAP family member 6	925	0.59
chrX_78404824_78405114	0.71	GPR174	G protein-coupled receptor 174	21500	0.29
chr7_106766845_106767175	0.71	CTA-360L10.1		7168	0.23
chr15_86234321_86234539	0.71	RP11-815J21.1		9910	0.12
chr14_25143375_25143614	0.70	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	40021	0.14
chr14_22937868_22938019	0.70	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	7353	0.1
chr14_98442707_98443118	0.70	C14orf64	chromosome 14 open reading frame 64	1471	0.59
chr16_27415358_27415584	0.70	IL21R	interleukin 21 receptor	1048	0.56
chr17_2699201_2699651	0.70	RAP1GAP2	RAP1 GTPase activating protein 2	306	0.89
chr2_237446083_237446280	0.70	IQCA1	IQ motif containing with AAA domain 1	29996	0.19
chr13_75899167_75899318	0.69	TBC1D4	TBC1 domain family, member 4	16425	0.24
chr16_11145985_11146136	0.69	RP11-66H6.3		18899	0.19
chr1_175162248_175162570	0.69	KIAA0040	KIAA0040	330	0.93
chr7_150382525_150383418	0.69	GIMAP2	GTPase, IMAP family member 2	156	0.95
chr10_8179462_8179700	0.69	GATA3	GATA binding protein 3	82812	0.11
chr2_175460295_175460493	0.68	WIPF1	WAS/WASL interacting protein family, member 1	2099	0.3
chr16_79123602_79124194	0.68	RP11-556H2.3		49	0.98
chr6_133067698_133067849	0.67	RP1-55C23.7		6041	0.13
chrX_77582442_77582995	0.67	CYSLTR1	cysteinyl leukotriene receptor 1	262	0.96
chr4_109028345_109028496	0.67	LEF1	lymphoid enhancer-binding factor 1	59037	0.12
chr1_198621955_198622106	0.67	PTPRC	protein tyrosine phosphatase, receptor type, C	13738	0.23
chr15_59344480_59344631	0.67	RNF111	ring finger protein 111	20732	0.16
chr12_109026699_109026850	0.67	SELPLG	selectin P ligand	896	0.46
chr19_44809165_44809335	0.67	ZNF235	zinc finger protein 235	51	0.97
chr9_134150778_134151758	0.67	FAM78A	family with sequence similarity 78, member A	666	0.69
chr9_100667597_100668036	0.66	C9orf156	chromosome 9 open reading frame 156	6937	0.17
chr1_24830928_24831111	0.66	RCAN3	RCAN family member 3	1632	0.35
chr5_118623311_118623849	0.66	ENSG00000243333	.	18746	0.17
chr9_123684795_123684946	0.65	TRAF1	TNF receptor-associated factor 1	6177	0.23
chr17_64327814_64327965	0.65	PRKCA	protein kinase C, alpha	28945	0.16
chr3_13462158_13462340	0.65	NUP210	nucleoporin 210kDa	440	0.87
chr1_236051645_236051799	0.65	LYST	lysosomal trafficking regulator	4850	0.19
chr2_237446743_237446920	0.65	ACKR3	atypical chemokine receptor 3	29599	0.19
chr20_62271866_62272113	0.65	STMN3	stathmin-like 3	12130	0.09
chr6_31544266_31544562	0.65	TNF	tumor necrosis factor	1070	0.2
chr17_76123581_76124282	0.65	TMC6	transmembrane channel-like 6	780	0.49
chr14_22982783_22983297	0.65	TRAJ15	T cell receptor alpha joining 15	15540	0.1
chr9_274688_274839	0.64	DOCK8	dedicator of cytokinesis 8	1693	0.31
chr3_18479661_18479848	0.64	SATB1	SATB homeobox 1	430	0.85
chr2_112939934_112940174	0.64	FBLN7	fibulin 7	594	0.8
chr11_118755543_118755694	0.64	CXCR5	chemokine (C-X-C motif) receptor 5	1143	0.3
chr1_167601517_167601668	0.64	RP3-455J7.4		1681	0.33
chr3_151961203_151961354	0.64	MBNL1	muscleblind-like splicing regulator 1	24551	0.2
chr10_30993847_30994006	0.64	SVILP1	supervillin pseudogene 1	9076	0.27
chr17_28134983_28135134	0.64	ENSG00000252657	.	30421	0.12
chr7_142344805_142344957	0.64	MTRNR2L6	MT-RNR2-like 6	29223	0.21
chr10_14611757_14612021	0.63	FAM107B	family with sequence similarity 107, member B	2140	0.39
chr7_623467_623815	0.63	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta	18679	0.14
chr19_2562041_2562223	0.63	CTC-265F19.2		49728	0.09
chr2_237445797_237446029	0.63	IQCA1	IQ motif containing with AAA domain 1	29728	0.19
chr2_85534473_85534624	0.63	ENSG00000221579	.	8391	0.11
chr12_57872273_57872424	0.63	ARHGAP9	Rho GTPase activating protein 9	45	0.94
chr16_3125184_3125385	0.63	ENSG00000252561	.	5760	0.06
chr2_172175996_172176199	0.63	METTL8	methyltransferase like 8	19669	0.24
chr18_63017285_63017436	0.62	CDH7	cadherin 7, type 2	400128	0.01
chr4_7761238_7761507	0.62	AFAP1-AS1	AFAP1 antisense RNA 1	5555	0.25
chr14_22938092_22938243	0.62	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	7129	0.11
chr2_198172874_198173132	0.62	ANKRD44	ankyrin repeat domain 44	2508	0.23
chr12_6554914_6555065	0.62	CD27	CD27 molecule	956	0.36
chr1_31223372_31223523	0.62	LAPTM5	lysosomal protein transmembrane 5	7220	0.16
chr17_29638804_29639264	0.62	EVI2B	ecotropic viral integration site 2B	2068	0.22
chr22_37562830_37562981	0.62	RP1-151B14.6		108	0.94
chr3_172235814_172236037	0.61	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	5340	0.27
chr3_71773124_71773375	0.61	EIF4E3	eukaryotic translation initiation factor 4E family member 3	1277	0.5
chr9_117147390_117147560	0.61	AKNA	AT-hook transcription factor	2768	0.28
chr18_67623845_67624178	0.61	CD226	CD226 molecule	105	0.98
chr12_6899553_6899934	0.61	CD4	CD4 molecule	1009	0.28
chr22_17567534_17567787	0.61	IL17RA	interleukin 17 receptor A	1811	0.31
chr18_13383808_13383959	0.61	LDLRAD4	low density lipoprotein receptor class A domain containing 4	1330	0.39
chr2_237447196_237447364	0.61	ACKR3	atypical chemokine receptor 3	29150	0.19
chr1_31227757_31227908	0.60	LAPTM5	lysosomal protein transmembrane 5	2835	0.23
chr10_81678709_81678860	0.60	SFTPD	surfactant protein D	30075	0.2
chr2_204570249_204570400	0.60	CD28	CD28 molecule	874	0.69
chr19_17516551_17516849	0.60	MVB12A	multivesicular body subunit 12A	150	0.6
chr17_11040783_11040934	0.60	ENSG00000243346	.	19914	0.24
chr2_10470298_10470561	0.60	HPCAL1	hippocalcin-like 1	26603	0.16
chr1_78392239_78392485	0.60	NEXN	nexilin (F actin binding protein)	8549	0.18
chr8_82021757_82021939	0.60	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	2455	0.41
chr6_209495_209646	0.59	DUSP22	dual specificity phosphatase 22	82060	0.11
chr13_31311572_31311749	0.59	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	2015	0.45
chr11_118087227_118087423	0.59	AMICA1	adhesion molecule, interacts with CXADR antigen 1	1719	0.29
chr4_40211899_40212136	0.59	RHOH	ras homolog family member H	10053	0.22
chr13_49065972_49066123	0.59	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	41166	0.17
chr17_78237440_78238417	0.59	RNF213	ring finger protein 213	3259	0.2
chr22_31336224_31336733	0.59	MORC2	MORC family CW-type zinc finger 2	7597	0.16
chrX_48776392_48776920	0.59	PIM2	pim-2 oncogene	355	0.76
chr20_57735286_57735495	0.59	ZNF831	zinc finger protein 831	30685	0.19
chr13_42033292_42033443	0.59	RGCC	regulator of cell cycle	1672	0.31
chr17_266453_266873	0.59	AC108004.3		2849	0.2
chr9_101899616_101899767	0.58	ENSG00000252942	.	8557	0.19
chr17_41393290_41393559	0.58	ENSG00000236383	.	10086	0.14
chr11_2466894_2467127	0.58	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	789	0.56
chr1_100887352_100887656	0.58	ENSG00000216067	.	43173	0.14
chr1_108505703_108505854	0.58	VAV3-AS1	VAV3 antisense RNA 1	1287	0.41
chr5_118607055_118607314	0.58	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2735	0.27
chr22_30617296_30617447	0.58	RP3-438O4.4		14273	0.11
chr2_197065721_197065922	0.58	ENSG00000239161	.	14225	0.18
chr3_16330036_16330187	0.58	OXNAD1	oxidoreductase NAD-binding domain containing 1	19363	0.15
chr1_101705566_101705834	0.58	RP4-575N6.5		3014	0.19
chr16_27413508_27414237	0.58	IL21R	interleukin 21 receptor	377	0.88
chr7_1979810_1980119	0.58	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	221	0.96
chr14_98442268_98442419	0.57	C14orf64	chromosome 14 open reading frame 64	2040	0.5
chr20_37435342_37435890	0.57	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	1249	0.47
chr7_6065967_6066118	0.57	EIF2AK1	eukaryotic translation initiation factor 2-alpha kinase 1	141	0.91
chr2_158292414_158292565	0.57	CYTIP	cytohesin 1 interacting protein	3437	0.27
chr8_37751638_37751789	0.57	RAB11FIP1	RAB11 family interacting protein 1 (class I)	5259	0.15
chrY_15016234_15016524	0.57	DDX3Y	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	350	0.93
chr21_36410157_36410308	0.57	RUNX1	runt-related transcription factor 1	11230	0.32
chr5_118609514_118610204	0.57	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	5410	0.21
chr5_35859258_35859647	0.57	IL7R	interleukin 7 receptor	2458	0.3
chr4_154443549_154443747	0.56	KIAA0922	KIAA0922	33400	0.2
chr14_99733165_99733625	0.56	AL109767.1		4110	0.24
chr19_47689837_47689988	0.56	ENSG00000265134	.	40287	0.1
chr11_95420136_95420287	0.56	FAM76B	family with sequence similarity 76, member B	99758	0.08
chr10_30707556_30707739	0.56	MAP3K8	mitogen-activated protein kinase kinase kinase 8	15219	0.19
chr20_37501287_37501438	0.56	ENSG00000240474	.	51	0.98
chr12_92532725_92532888	0.56	C12orf79	chromosome 12 open reading frame 79	2009	0.29
chr16_29677209_29677502	0.56	QPRT	quinolinate phosphoribosyltransferase	2755	0.17
chr2_240219542_240220118	0.55	ENSG00000265215	.	7327	0.19
chr21_46346446_46346882	0.55	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	1969	0.18
chr5_137416910_137417200	0.55	WNT8A	wingless-type MMTV integration site family, member 8A	2526	0.17
chr2_223290336_223290619	0.55	SGPP2	sphingosine-1-phosphate phosphatase 2	1241	0.5
chr3_108541565_108541773	0.55	TRAT1	T cell receptor associated transmembrane adaptor 1	50	0.98
chr6_25136833_25137456	0.55	ENSG00000222373	.	55497	0.11
chr13_31312414_31312565	0.55	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	2844	0.37
chr10_29769061_29769212	0.55	SVIL	supervillin	16311	0.22
chr11_108724912_108725630	0.55	ENSG00000201243	.	150973	0.04
chr10_11221601_11222262	0.55	RP3-323N1.2		8592	0.22
chr3_187455559_187456689	0.55	BCL6	B-cell CLL/lymphoma 6	392	0.87
chr7_150436038_150436258	0.55	GIMAP5	GTPase, IMAP family member 5	1712	0.32
chr15_57199386_57199736	0.55	ZNF280D	zinc finger protein 280D	11208	0.22
chrX_40029862_40030013	0.55	BCOR	BCL6 corepressor	6636	0.32
chr1_111215065_111215351	0.55	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	2447	0.28
chr3_13053634_13053814	0.54	IQSEC1	IQ motif and Sec7 domain 1	25188	0.24
chr4_38511545_38511706	0.54	RP11-617D20.1		114571	0.06
chr17_33863414_33863594	0.54	SLFN12L	schlafen family member 12-like	1376	0.29

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.4	1.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3	1.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	0.9	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.2	1.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.2	0.6	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.2	0.4	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.2	0.6	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2	0.8	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.2	1.0	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.2	0.6	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2	1.0	GO:0002363	alpha-beta T cell lineage commitment(GO:0002363)
0.2	0.6	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.2	0.7	GO:0010508	positive regulation of autophagy(GO:0010508)
0.2	0.7	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.5	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.2	1.4	GO:0015671	oxygen transport(GO:0015671)
0.2	0.5	GO:0070295	renal water absorption(GO:0070295)
0.2	1.8	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.2	0.6	GO:0000089	mitotic metaphase(GO:0000089)
0.2	0.3	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.2	0.5	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.6	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.6	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.1	1.2	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.4	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1	0.4	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.6	GO:0002423	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.3	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.1	1.0	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.4	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.1	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.4	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.3	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.1	GO:0046643	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.2	GO:0002836	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.5	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.5	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	0.3	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1	0.5	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.1	0.7	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.4	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.1	0.2	GO:0002664	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.9	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.1	0.3	GO:0015705	iodide transport(GO:0015705)
0.1	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.3	GO:0006667	sphinganine metabolic process(GO:0006667)
0.1	0.1	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.3	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.1	0.2	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.3	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.2	GO:0001783	B cell apoptotic process(GO:0001783)
0.1	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	1.9	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1	0.1	GO:0032663	regulation of interleukin-2 production(GO:0032663) negative regulation of interleukin-2 production(GO:0032703)
0.1	1.2	GO:0030101	natural killer cell activation(GO:0030101)
0.1	0.3	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.2	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1	0.3	GO:0003032	detection of oxygen(GO:0003032)
0.1	1.0	GO:0071514	genetic imprinting(GO:0071514)
0.1	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1	0.4	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.6	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.3	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1	0.3	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	1.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1	0.6	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1	0.1	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1	0.4	GO:0048535	lymph node development(GO:0048535)
0.1	0.4	GO:0001782	B cell homeostasis(GO:0001782)
0.1	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.9	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.1	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.3	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	0.3	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.2	GO:0003170	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.1	0.2	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	1.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.1	0.3	GO:0006991	response to sterol depletion(GO:0006991)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.1	0.2	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.3	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.2	GO:0045576	mast cell activation(GO:0045576)
0.1	0.7	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.2	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.2	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.1	0.1	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.2	GO:0048478	replication fork protection(GO:0048478)
0.1	0.3	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.1	0.2	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.7	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0	0.1	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.2	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	1.3	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.3	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	1.1	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.2	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.3	GO:0034311	diol metabolic process(GO:0034311)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.3	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.2	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0015809	arginine transport(GO:0015809)
0.0	0.3	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.2	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0034391	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0	0.1	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.2	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:1903519	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.2	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.6	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.3	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.3	GO:0042267	natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.2	GO:0032352	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.0	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.2	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0035269	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.5	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.9	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.2	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.2	GO:0048242	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.3	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.3	GO:0051322	anaphase(GO:0051322)
0.0	0.4	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.3	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	1.1	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.3	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.1	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.0	GO:0030815	negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818)
0.0	0.5	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.6	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.1	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.2	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.6	GO:0006997	nucleus organization(GO:0006997)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.2	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.2	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.2	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.3	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.1	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	1.1	GO:0097194	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.6	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.5	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.2	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.0	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.0	GO:0009264	deoxyribonucleotide catabolic process(GO:0009264)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.2	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	1.0	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.2	GO:0010039	response to iron ion(GO:0010039)
0.0	0.0	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.1	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.3	GO:0031280	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.5	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.1	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.1	GO:0016445	somatic diversification of immune receptors(GO:0002200) somatic diversification of immunoglobulins(GO:0016445)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0007440	foregut morphogenesis(GO:0007440)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.3	GO:0030593	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0034444	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0071222	cellular response to lipopolysaccharide(GO:0071222)
0.0	0.6	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.0	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.4	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.0	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.3	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.2	GO:0030225	macrophage differentiation(GO:0030225)
0.0	0.0	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.0	GO:0071622	regulation of granulocyte chemotaxis(GO:0071622)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.0	GO:0060405	regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.2	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.3	GO:0007632	visual behavior(GO:0007632)
0.0	0.1	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.0	0.4	GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0043474	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.0	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	0.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0019048	modulation by virus of host morphology or physiology(GO:0019048)
0.0	0.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0036230	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0060761	negative regulation of response to cytokine stimulus(GO:0060761)
0.0	0.1	GO:0051187	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) cofactor catabolic process(GO:0051187)
0.0	0.0	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.4	GO:0006909	phagocytosis(GO:0006909)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.1	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.0	GO:0032769	negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.0	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.0	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.1	GO:0042516	tyrosine phosphorylation of Stat3 protein(GO:0042503) regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0	0.5	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.0	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.0	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0051928	positive regulation of calcium ion transport(GO:0051928)
0.0	0.0	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0043954	cellular component maintenance(GO:0043954)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0019835	cytolysis(GO:0019835)
0.0	0.2	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.3	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.3	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.1	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.2	GO:0006284	base-excision repair(GO:0006284)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.6	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:1902932	positive regulation of alcohol biosynthetic process(GO:1902932)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0015992	proton transport(GO:0015992)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.6	GO:0061025	membrane fusion(GO:0061025)
0.0	0.4	GO:0051028	mRNA transport(GO:0051028)
0.0	0.0	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.6	GO:0000236	mitotic prometaphase(GO:0000236)
0.0	0.1	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.6	GO:0006754	ATP biosynthetic process(GO:0006754)
0.0	4.8	GO:0006955	immune response(GO:0006955)
0.0	0.1	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.0	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.0	GO:0032770	positive regulation of monooxygenase activity(GO:0032770)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.0	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	1.0	GO:0048011	neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0015669	gas transport(GO:0015669)
0.0	0.0	GO:0060251	regulation of glial cell proliferation(GO:0060251)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0008306	associative learning(GO:0008306)
0.0	0.2	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.1	GO:0044036	cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.0	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:1902743	regulation of lamellipodium organization(GO:1902743)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	0.6	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	1.7	GO:0042101	T cell receptor complex(GO:0042101)
0.1	1.1	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.7	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.4	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.1	1.0	GO:0001772	immunological synapse(GO:0001772)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.3	GO:0000800	lateral element(GO:0000800)
0.1	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.6	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	0.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.3	GO:0001739	sex chromatin(GO:0001739)
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.2	GO:0005638	lamin filament(GO:0005638)
0.1	0.5	GO:0045335	phagocytic vesicle(GO:0045335)
0.1	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.5	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.4	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.9	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.5	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.6	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.2	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.6	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	1.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.5	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	1.9	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	1.0	GO:0005657	replication fork(GO:0005657)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	4.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.9	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.4	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	1.1	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.9	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.4	GO:0097610	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.5	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	1.1	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.3	GO:0005844	polysome(GO:0005844)
0.0	0.0	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.5	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.0	GO:0051233	spindle midzone(GO:0051233)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.2	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.3	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.2	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.4	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.0	GO:0030897	HOPS complex(GO:0030897)
0.0	0.4	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.2	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	1.1	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	1.1	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.8	GO:0005769	early endosome(GO:0005769)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	1.3	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.4	GO:0000922	spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.3	1.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.3	1.4	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3	0.8	GO:0042608	T cell receptor binding(GO:0042608)
0.2	0.9	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2	0.6	GO:0050544	arachidonic acid binding(GO:0050544)
0.2	0.5	GO:0015254	glycerol channel activity(GO:0015254)
0.2	0.9	GO:0051400	BH domain binding(GO:0051400)
0.1	0.4	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	1.0	GO:0005522	profilin binding(GO:0005522)
0.1	2.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.4	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.4	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	0.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	1.0	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	1.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	1.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.5	GO:0004904	interferon receptor activity(GO:0004904)
0.1	1.4	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.5	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.3	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.5	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.4	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.3	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.6	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	1.9	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.1	0.4	GO:0031013	troponin I binding(GO:0031013)
0.1	0.6	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.6	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.4	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.7	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.1	GO:0001846	opsonin binding(GO:0001846)
0.1	0.6	GO:0046625	sphingolipid binding(GO:0046625)
0.1	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.1	0.4	GO:0031701	angiotensin receptor binding(GO:0031701)
0.1	0.9	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1	0.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.2	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	1.7	GO:0003823	antigen binding(GO:0003823)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.8	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.2	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.2	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.6	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.3	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.4	GO:0030276	clathrin binding(GO:0030276)
0.0	0.3	GO:0001848	complement binding(GO:0001848)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.6	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	1.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.3	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	1.0	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.3	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.4	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.3	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	1.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	1.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	1.1	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	1.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0042287	MHC protein binding(GO:0042287) MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.5	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.4	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.6	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.6	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.0	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.3	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0035240	dopamine binding(GO:0035240)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.0	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.4	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.6	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.3	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.4	GO:0051540	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0	0.6	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	3.6	GO:0005525	GTP binding(GO:0005525)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.0	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	2.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	7.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.9	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	1.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	0.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.4	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	1.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	2.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	0.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.7	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	2.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	1.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.8	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	1.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.6	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.8	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.6	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.4	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.2	PID ATM PATHWAY	ATM pathway
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID P73PATHWAY	p73 transcription factor network
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.3	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	2.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	0.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.6	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	0.9	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.9	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	1.0	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	1.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.1	3.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	3.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.1	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	0.8	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	0.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	2.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	0.3	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	1.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.9	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	1.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	1.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	1.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	1.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.9	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.3	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling

Results for STAT5A

Z-value: 1.98

Motif logo

Transcription factors associated with STAT5A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the STAT5A motif across conditions

Conditions sorted by the z-value of the STAT5A motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: