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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for T

Z-value: 0.61

Motif logo

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Transcription factors associated with T

Gene Symbol Gene ID Gene Info
T
ENSG00000164458.5 T

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Tchr6_166582350_1665825012370.943451-0.442.3e-01Click!
Tchr6_166581874_166582172840.9777630.039.3e-01Click!

Activity of the T motif across conditions

Conditions sorted by the z-value of the T motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_120687736_120687954 0.52 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 493
 0.83
chr1_203735045_203735272 0.50 LAX1
 lymphocyte transmembrane adaptor 1
 853
 0.57
chr15_40599321_40599893 0.44 PLCB2
 phospholipase C, beta 2
 419
 0.68
chr10_6103505_6103656 0.43 IL2RA
 interleukin 2 receptor, alpha
 673
 0.64
chr3_114014633_114014828 0.42 TIGIT
 T cell immunoreceptor with Ig and ITIM domains
 896
 0.58
chrX_128913998_128914362 0.41 SASH3
 SAM and SH3 domain containing 3
 220
 0.94
chr14_92331424_92331867 0.40 TC2N
 tandem C2 domains, nuclear
 2228
 0.32
chr9_95727676_95727827 0.40 FGD3
 FYVE, RhoGEF and PH domain containing 3
 1508
 0.45
chr21_15917916_15918619 0.39 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 395
 0.89
chr3_150920478_150920863 0.38 GPR171
 G protein-coupled receptor 171
 309
 0.87
chr9_95728150_95728303 0.36 FGD3
 FYVE, RhoGEF and PH domain containing 3
 1983
 0.37
chr13_99957510_99957765 0.35 GPR183
 G protein-coupled receptor 183
 2022
 0.34
chr4_100738344_100738640 0.35 DAPP1
 dual adaptor of phosphotyrosine and 3-phosphoinositides
 489
 0.85
chr1_6525547_6525781 0.35 TNFRSF25
 tumor necrosis factor receptor superfamily, member 25
 26
 0.96
chr1_9689695_9689868 0.34 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 22009
 0.15
chr1_198615772_198616039 0.34 PTPRC
 protein tyrosine phosphatase, receptor type, C
 7613
 0.25
chr7_962027_962293 0.33 ADAP1
 ArfGAP with dual PH domains 1
 1634
 0.31
chr6_130536667_130536818 0.33 SAMD3
 sterile alpha motif domain containing 3
 45
 0.99
chr3_111261315_111261845 0.33 CD96
 CD96 molecule
 583
 0.82
chr8_48515171_48515322 0.32 SPIDR
 scaffolding protein involved in DNA repair
 56980
 0.12
chr6_20336872_20337023 0.31 E2F3
 E2F transcription factor 3
 65451
 0.1
chr2_2650168_2650319 0.31 MYT1L
 myelin transcription factor 1-like
 315277
 0.01
chr14_102280520_102280788 0.30 CTD-2017C7.2
3996
 0.17
chr14_22999291_22999566 0.30 TRAJ15
 T cell receptor alpha joining 15
 848
 0.46
chr14_22994017_22994177 0.29 TRAJ15
 T cell receptor alpha joining 15
 4483
 0.13
chr3_46396063_46396214 0.29 CCR2
 chemokine (C-C motif) receptor 2
 521
 0.76
chr2_120690048_120690199 0.29 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 71
 0.98
chr11_118177311_118177735 0.29 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
 1909
 0.24
chr22_20784096_20784540 0.29 SCARF2
 scavenger receptor class F, member 2
 7794
 0.11
chr1_198616268_198616512 0.29 PTPRC
 protein tyrosine phosphatase, receptor type, C
 8098
 0.25
chr5_150593261_150593549 0.29 GM2A
 GM2 ganglioside activator
 1694
 0.36
chr5_180231596_180231747 0.28 MGAT1
 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
 748
 0.63
chr16_88717586_88717845 0.28 CYBA
 cytochrome b-245, alpha polypeptide
 155
 0.9
chr20_45623189_45623371 0.28 EYA2
 eyes absent homolog 2 (Drosophila)
 4640
 0.32
chr14_55800013_55800175 0.28 RP11-665C16.5
6125
 0.25
chr11_2466894_2467127 0.28 KCNQ1
 potassium voltage-gated channel, KQT-like subfamily, member 1
 789
 0.56
chr11_127906960_127907260 0.27 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 468179
 0.01
chr13_41589998_41590808 0.27 ELF1
 E74-like factor 1 (ets domain transcription factor)
 3047
 0.26
chr22_40858929_40859404 0.27 MKL1
 megakaryoblastic leukemia (translocation) 1
 256
 0.92
chr3_185331003_185331154 0.27 SENP2
 SUMO1/sentrin/SMT3 specific peptidase 2
 65
 0.98
chr17_72735282_72735631 0.27 RAB37
 RAB37, member RAS oncogene family
 2085
 0.18
chr2_237446743_237446920 0.27 ACKR3
 atypical chemokine receptor 3
 29599
 0.19
chr13_46749322_46749478 0.27 ENSG00000240767
 .
 5517
 0.17
chr2_235400500_235400697 0.27 ARL4C
 ADP-ribosylation factor-like 4C
 4646
 0.36
chr19_13215909_13216097 0.27 LYL1
 lymphoblastic leukemia derived sequence 1
 2028
 0.18
chr6_38019767_38019918 0.26 ZFAND3
 zinc finger, AN1-type domain 3
 122107
 0.06
chr22_40299734_40299885 0.26 GRAP2
 GRB2-related adaptor protein 2
 2696
 0.25
chr12_32119532_32119743 0.26 KIAA1551
 KIAA1551
 4214
 0.28
chr22_40307152_40307436 0.26 GRAP2
 GRB2-related adaptor protein 2
 10181
 0.17
chr16_53491555_53491772 0.26 RBL2
 retinoblastoma-like 2 (p130)
 7675
 0.16
chr1_67398755_67399224 0.26 MIER1
 mesoderm induction early response 1, transcriptional regulator
 3063
 0.27
chrX_40030247_40030398 0.26 BCOR
 BCL6 corepressor
 6251
 0.32
chr1_12230241_12230523 0.26 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 3322
 0.2
chr16_84634203_84634572 0.25 RP11-61F12.1
6388
 0.18
chr22_40297106_40297391 0.25 GRAP2
 GRB2-related adaptor protein 2
 135
 0.96
chr14_55799126_55799413 0.25 RP11-665C16.5
6950
 0.25
chr4_38916539_38916690 0.25 ENSG00000207944
 .
 46961
 0.11
chr12_46062713_46062864 0.24 ARID2
 AT rich interactive domain 2 (ARID, RFX-like)
 60660
 0.15
chr15_65597552_65597703 0.24 ENSG00000200156
 .
 612
 0.64
chr12_1920714_1920865 0.24 CACNA2D4
 calcium channel, voltage-dependent, alpha 2/delta subunit 4
 97
 0.97
chr10_71332813_71333013 0.24 NEUROG3
 neurogenin 3
 81
 0.97
chr5_32583768_32584065 0.24 SUB1
 SUB1 homolog (S. cerevisiae)
 1689
 0.49
chr5_32532091_32532542 0.24 SUB1
 SUB1 homolog (S. cerevisiae)
 392
 0.9
chr6_12061250_12061691 0.24 HIVEP1
 human immunodeficiency virus type I enhancer binding protein 1
 45650
 0.18
chrX_57313067_57313960 0.24 FAAH2
 fatty acid amide hydrolase 2
 374
 0.92
chr5_59062656_59062927 0.23 PDE4D
 phosphodiesterase 4D, cAMP-specific
 1671
 0.51
chr15_60296272_60296423 0.23 FOXB1
 forkhead box B1
 74
 0.99
chr18_60982497_60982692 0.23 RP11-28F1.2
1279
 0.41
chr14_98444010_98444505 0.23 C14orf64
 chromosome 14 open reading frame 64
 126
 0.98
chr19_49840027_49840178 0.23 CD37
 CD37 molecule
 370
 0.72
chr2_112178355_112178506 0.23 ENSG00000266139
 .
 99762
 0.09
chr22_40640074_40640407 0.23 TNRC6B
 trinucleotide repeat containing 6B
 20767
 0.22
chr10_127731141_127731292 0.23 FANK1
 fibronectin type III and ankyrin repeat domains 1
 47230
 0.14
chr7_35730534_35730808 0.23 HERPUD2
 HERPUD family member 2
 3505
 0.27
chr2_101916869_101917041 0.23 RNF149
 ring finger protein 149
 8203
 0.17
chr11_45377791_45377942 0.23 SYT13
 synaptotagmin XIII
 69996
 0.11
chr4_14169430_14169581 0.22 ENSG00000252092
 .
 509254
 0.0
chrX_128914480_128914899 0.22 SASH3
 SAM and SH3 domain containing 3
 729
 0.68
chr19_14260226_14260973 0.22 LPHN1
 latrophilin 1
 3052
 0.14
chr12_9911780_9911931 0.22 CD69
 CD69 molecule
 1642
 0.33
chr10_102270947_102271098 0.22 SEC31B
 SEC31 homolog B (S. cerevisiae)
 8569
 0.16
chr1_150535533_150535831 0.22 ADAMTSL4-AS1
 ADAMTSL4 antisense RNA 1
 1713
 0.17
chr1_167485802_167485953 0.22 CD247
 CD247 molecule
 1898
 0.36
chr10_9271793_9271944 0.22 ENSG00000212505
 .
 573074
 0.0
chr1_200991644_200992373 0.22 KIF21B
 kinesin family member 21B
 528
 0.78
chr4_6912691_6912996 0.21 TBC1D14
 TBC1 domain family, member 14
 868
 0.61
chr1_244483301_244483484 0.21 C1orf100
 chromosome 1 open reading frame 100
 32545
 0.2
chrX_70323668_70324217 0.21 CXorf65
 chromosome X open reading frame 65
 2513
 0.16
chr2_225808771_225808936 0.21 DOCK10
 dedicator of cytokinesis 10
 2929
 0.39
chr10_6627252_6627403 0.21 PRKCQ
 protein kinase C, theta
 5064
 0.34
chr17_76730952_76731103 0.21 CYTH1
 cytohesin 1
 1945
 0.35
chr5_67576190_67576341 0.21 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 130
 0.98
chr8_27183037_27183778 0.21 PTK2B
 protein tyrosine kinase 2 beta
 326
 0.9
chr20_62271176_62271486 0.21 CTD-3184A7.4
12728
 0.09
chr16_31468522_31468673 0.20 ARMC5
 armadillo repeat containing 5
 804
 0.4
chr1_27686628_27686822 0.20 MAP3K6
 mitogen-activated protein kinase kinase kinase 6
 3717
 0.14
chr17_2699201_2699651 0.20 RAP1GAP2
 RAP1 GTPase activating protein 2
 306
 0.89
chr19_16477276_16478284 0.20 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 5016
 0.17
chr15_60882704_60882968 0.20 RORA
 RAR-related orphan receptor A
 1904
 0.39
chr1_6054566_6054852 0.20 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
 1938
 0.28
chr17_20602116_20602267 0.20 AC126365.1
17605
 0.23
chr2_68994473_68994840 0.20 ARHGAP25
 Rho GTPase activating protein 25
 7277
 0.25
chr2_109238478_109238884 0.20 LIMS1
 LIM and senescent cell antigen-like domains 1
 959
 0.64
chr19_30158859_30159039 0.20 PLEKHF1
 pleckstrin homology domain containing, family F (with FYVE domain) member 1
 1168
 0.55
chr10_23631330_23631481 0.20 RP11-371A19.2
1481
 0.31
chr1_89740013_89740507 0.20 GBP5
 guanylate binding protein 5
 1716
 0.37
chr1_111173785_111173949 0.20 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
 229
 0.93
chr10_102133099_102133250 0.20 ENSG00000212325
 .
 25029
 0.12
chr17_56410108_56410593 0.20 MIR142
 microRNA 142
 481
 0.66
chr3_71772714_71772865 0.20 EIF4E3
 eukaryotic translation initiation factor 4E family member 3
 1737
 0.4
chr8_38215592_38215743 0.20 RP11-513D5.2
22168
 0.11
chr19_6773186_6773436 0.19 VAV1
 vav 1 guanine nucleotide exchange factor
 342
 0.82
chr1_19284092_19284243 0.19 IFFO2
 intermediate filament family orphan 2
 987
 0.58
chr12_12712693_12713134 0.19 DUSP16
 dual specificity phosphatase 16
 1098
 0.58
chr14_22236992_22237143 0.19 ENSG00000222776
 .
 11718
 0.25
chr2_70321532_70321889 0.19 PCBP1-AS1
 PCBP1 antisense RNA 1
 5732
 0.17
chr6_167367959_167368110 0.19 RP11-514O12.4
1578
 0.28
chrX_144503620_144503771 0.19 SPANXN1
 SPANX family, member N1
 175347
 0.03
chr6_13428686_13428841 0.19 GFOD1
 glucose-fructose oxidoreductase domain containing 1
 20394
 0.18
chr1_161008159_161008677 0.19 TSTD1
 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
 101
 0.93
chr7_8010063_8010681 0.19 AC006042.7
838
 0.45
chrY_2804797_2805062 0.19 ZFY
 zinc finger protein, Y-linked
 1383
 0.54
chr17_7239932_7240900 0.19 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
 507
 0.51
chr1_181003153_181003921 0.19 MR1
 major histocompatibility complex, class I-related
 398
 0.84
chr1_205410656_205410807 0.19 ENSG00000199059
 .
 6795
 0.17
chr5_149790034_149790185 0.19 CD74
 CD74 molecule, major histocompatibility complex, class II invariant chain
 2186
 0.28
chr16_11678677_11678828 0.18 LITAF
 lipopolysaccharide-induced TNF factor
 1477
 0.42
chr1_24862040_24862255 0.18 ENSG00000266551
 .
 5943
 0.18
chr3_108544304_108544541 0.18 TRAT1
 T cell receptor associated transmembrane adaptor 1
 2803
 0.36
chr14_22992025_22992229 0.18 TRAJ15
 T cell receptor alpha joining 15
 6453
 0.11
chr17_56477664_56477815 0.18 RNF43
 ring finger protein 43
 2343
 0.23
chr3_177077016_177077315 0.18 ENSG00000252028
 .
 144175
 0.05
chr18_13266147_13266338 0.18 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 11860
 0.19
chr22_18250195_18250346 0.18 ENSG00000264757
 .
 3245
 0.23
chr11_128375528_128375679 0.18 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 314
 0.92
chr22_30617296_30617447 0.18 RP3-438O4.4
14273
 0.11
chr6_144472562_144472798 0.18 STX11
 syntaxin 11
 1017
 0.64
chr11_128387324_128387802 0.18 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 4533
 0.26
chr12_121476370_121477291 0.18 OASL
 2'-5'-oligoadenylate synthetase-like
 80
 0.96
chr11_2322055_2322323 0.18 C11orf21
 chromosome 11 open reading frame 21
 954
 0.34
chr11_95829215_95829366 0.18 MTMR2
 myotubularin related protein 2
 171831
 0.03
chr18_77283391_77284187 0.18 AC018445.1
 Uncharacterized protein
 7732
 0.29
chr14_78108664_78108852 0.17 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 25642
 0.16
chr9_134608223_134608646 0.17 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 4491
 0.23
chr2_175460831_175461348 0.17 WIPF1
 WAS/WASL interacting protein family, member 1
 1404
 0.41
chr19_1021420_1021571 0.17 ENSG00000207357
 .
 26
 0.83
chr4_154390309_154390666 0.17 KIAA0922
 KIAA0922
 2986
 0.33
chrX_107070045_107070650 0.17 MID2
 midline 2
 703
 0.7
chr20_17591518_17591669 0.17 ENSG00000202260
 .
 34438
 0.14
chr1_180469296_180469554 0.17 ACBD6
 acyl-CoA binding domain containing 6
 2664
 0.28
chr17_5186506_5186842 0.17 RABEP1
 rabaptin, RAB GTPase binding effector protein 1
 892
 0.56
chr10_13382497_13382864 0.17 SEPHS1
 selenophosphate synthetase 1
 110
 0.97
chr5_136467995_136468146 0.17 ENSG00000222285
 .
 163075
 0.04
chr14_50053552_50053772 0.17 RN7SL1
 RNA, 7SL, cytoplasmic 1
 364
 0.55
chr22_40881445_40881596 0.17 MKL1
 megakaryoblastic leukemia (translocation) 1
 22082
 0.15
chr19_6738870_6739021 0.17 TRIP10
 thyroid hormone receptor interactor 10
 746
 0.45
chr2_197040446_197040597 0.17 STK17B
 serine/threonine kinase 17b
 530
 0.79
chr19_10381107_10381258 0.17 ICAM1
 intercellular adhesion molecule 1
 329
 0.72
chr10_82225109_82225470 0.17 TSPAN14
 tetraspanin 14
 6231
 0.22
chr5_175968739_175969051 0.16 CDHR2
 cadherin-related family member 2
 617
 0.6
chr13_46742646_46742820 0.16 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 79
 0.95
chr17_74067054_74067205 0.16 SRP68
 signal recognition particle 68kDa
 1449
 0.26
chr19_52832897_52833072 0.16 ZNF610
 zinc finger protein 610
 6514
 0.11
chr19_33863850_33864075 0.16 CEBPG
 CCAAT/enhancer binding protein (C/EBP), gamma
 274
 0.92
chr7_26415346_26415505 0.16 AC004540.4
467
 0.85
chr22_37681278_37681429 0.16 CYTH4
 cytohesin 4
 2825
 0.23
chr19_42052916_42053110 0.16 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 2873
 0.23
chr2_192070921_192071072 0.16 MYO1B
 myosin IB
 38915
 0.17
chr19_10342329_10342480 0.16 DNMT1
 DNA (cytosine-5-)-methyltransferase 1
 442
 0.39
chr17_25958202_25958709 0.16 LGALS9
 lectin, galactoside-binding, soluble, 9
 222
 0.92
chr17_43306981_43307138 0.16 CTD-2020K17.1
7470
 0.1
chrX_78343760_78343985 0.16 GPR174
 G protein-coupled receptor 174
 82597
 0.11
chr2_242810596_242810747 0.16 CXXC11
 CXXC finger protein 11
 1210
 0.33
chr17_76255043_76255413 0.16 TMEM235
 transmembrane protein 235
 27106
 0.12
chr5_169723230_169723381 0.16 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 1926
 0.38
chr8_22876543_22876783 0.16 RP11-875O11.1
185
 0.92
chr1_19785278_19785429 0.16 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 25226
 0.14
chr19_7411383_7411820 0.16 CTB-133G6.1
2247
 0.26
chrY_21729398_21729741 0.16 TXLNG2P
 taxilin gamma 2, pseudogene
 301
 0.92
chr2_231646247_231646398 0.16 ENSG00000201044
 .
 29466
 0.17
chr5_35863104_35863313 0.16 IL7R
 interleukin 7 receptor
 6214
 0.22
chr5_100188986_100189137 0.16 ENSG00000221263
 .
 36792
 0.19
chr12_51782252_51782403 0.16 GALNT6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
 2756
 0.2
chr5_176728326_176728485 0.16 RAB24
 RAB24, member RAS oncogene family
 2302
 0.17
chr6_12010262_12011396 0.15 HIVEP1
 human immunodeficiency virus type I enhancer binding protein 1
 1404
 0.51
chr6_138776848_138777021 0.15 ENSG00000266555
 .
 20503
 0.19
chr3_16329814_16329965 0.15 OXNAD1
 oxidoreductase NAD-binding domain containing 1
 19141
 0.15
chr16_48642312_48642839 0.15 N4BP1
 NEDD4 binding protein 1
 1545
 0.4
chr6_47666717_47666868 0.15 GPR115
 G protein-coupled receptor 115
 503
 0.8
chr12_26999341_26999492 0.15 ITPR2
 inositol 1,4,5-trisphosphate receptor, type 2
 13285
 0.23
chr7_106505707_106506635 0.15 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
 247
 0.95
chr1_899115_899266 0.15 PLEKHN1
 pleckstrin homology domain containing, family N member 1
 2687
 0.12
chr17_75450826_75450977 0.15 SEPT9
 septin 9
 739
 0.6
chr1_201323781_201323932 0.15 TNNT2
 troponin T type 2 (cardiac)
 18526
 0.16
chr22_29563318_29563469 0.15 ENSG00000251952
 .
 24403
 0.12
chr2_102972689_102973095 0.15 IL18R1
 interleukin 18 receptor 1
 503
 0.79
chr6_170403243_170403627 0.15 RP11-302L19.1
74306
 0.11
chr12_92524835_92525431 0.15 C12orf79
 chromosome 12 open reading frame 79
 5664
 0.19
chr2_68593138_68593303 0.15 AC015969.3
504
 0.63
chrY_15590512_15590663 0.15 UTY
 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
 958
 0.72

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of T

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.3 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.3 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.3 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.1 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.3 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.2 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0002517 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.1 GO:0002335 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.2 GO:0002920 regulation of humoral immune response(GO:0002920)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.2 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.5 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.4 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0008420 CTD phosphatase activity(GO:0008420)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.0 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.0 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels