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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for TBP

Z-value: 1.77

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Transcription factors associated with TBP

Gene Symbol	Gene ID	Gene Info
TBP Ensembl NCBI GeneCards UniProt	ENSG00000112592.8	TATA-box binding protein

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_170864602_170864753	TBP	984	0.526838	-0.45	2.2e-01	Click!
chr6_170862818_170863042	TBP	460	0.496268	-0.38	3.1e-01	Click!
chr6_170864120_170864505	TBP	619	0.693260	0.29	4.5e-01	Click!
chr6_170863482_170864110	TBP	103	0.954903	-0.10	8.0e-01	Click!

Activity of the TBP motif across conditions

Conditions sorted by the z-value of the TBP motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_130181973_130182524	0.54	TMEM244	transmembrane protein 244	168	0.97
chr10_33245601_33245912	0.51	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	966	0.69
chr3_71176981_71177279	0.50	FOXP1	forkhead box P1	2614	0.43
chr18_12775334_12775517	0.49	ENSG00000201466	.	14709	0.18
chr4_109086177_109086328	0.49	LEF1	lymphoid enhancer-binding factor 1	1205	0.49
chr22_39638932_39639142	0.46	PDGFB	platelet-derived growth factor beta polypeptide	16	0.97
chr4_48134456_48134607	0.45	TXK	TXK tyrosine kinase	1742	0.32
chr8_71564383_71564535	0.44	ENSG00000243532	.	2659	0.21
chr2_12862265_12862722	0.43	TRIB2	tribbles pseudokinase 2	4129	0.3
chr9_73026004_73026213	0.43	KLF9	Kruppel-like factor 9	3432	0.34
chr1_113500392_113500555	0.42	SLC16A1	solute carrier family 16 (monocarboxylate transporter), member 1	838	0.54
chr4_110482724_110482875	0.42	CCDC109B	coiled-coil domain containing 109B	653	0.77
chr17_27137285_27137436	0.41	FAM222B	family with sequence similarity 222, member B	1882	0.16
chr5_6828115_6828430	0.41	ENSG00000200243	.	20303	0.27
chr2_234328713_234328864	0.41	DGKD	diacylglycerol kinase, delta 130kDa	31988	0.14
chr1_6551002_6551374	0.40	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	548	0.66
chr6_162975898_162976049	0.40	PACRG	PARK2 co-regulated	172191	0.04
chr14_50362239_50362940	0.40	ARF6	ADP-ribosylation factor 6	2779	0.17
chr7_142556554_142556705	0.39	EPHB6	EPH receptor B6	3806	0.19
chr21_26933768_26934400	0.39	ENSG00000234883	.	12208	0.19
chr11_118493105_118493350	0.39	AP002954.3		14111	0.11
chr2_43746685_43747132	0.39	THADA	thyroid adenoma associated	50746	0.15
chr12_120428180_120428604	0.39	CCDC64	coiled-coil domain containing 64	719	0.72
chr8_24771192_24771464	0.38	NEFM	neurofilament, medium polypeptide	51	0.94
chr1_193154702_193155811	0.38	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	528	0.8
chr3_16342795_16343107	0.37	RP11-415F23.2		12995	0.16
chr18_13437570_13437721	0.37	LDLRAD4-AS1	LDLRAD4 antisense RNA 1	10166	0.12
chrX_107685372_107685523	0.37	COL4A5	collagen, type IV, alpha 5	2335	0.32
chr10_116615954_116616468	0.37	FAM160B1	family with sequence similarity 160, member B1	4339	0.31
chr14_22952780_22952931	0.37	ENSG00000251002	.	907	0.37
chr14_22960619_22960887	0.37	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	4582	0.12
chr22_31336224_31336733	0.37	MORC2	MORC family CW-type zinc finger 2	7597	0.16
chr9_106345468_106345619	0.36	ENSG00000253031	.	106316	0.08
chr18_22906477_22906628	0.36	CTD-2006O16.2		24462	0.22
chr6_143205839_143206424	0.36	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	47947	0.17
chr1_90464057_90464208	0.35	ZNF326	zinc finger protein 326	3405	0.29
chr11_118175872_118176125	0.35	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	384	0.79
chr11_62308348_62308681	0.35	RP11-864I4.3		3730	0.11
chr12_9821605_9821756	0.35	CLEC2D	C-type lectin domain family 2, member D	629	0.61
chr2_162930539_162930947	0.35	DPP4	dipeptidyl-peptidase 4	309	0.82
chr18_8608259_8609220	0.35	RAB12	RAB12, member RAS oncogene family	704	0.71
chr7_559951_560161	0.35	PDGFA	platelet-derived growth factor alpha polypeptide	123	0.97
chr15_38849659_38849810	0.35	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	2549	0.27
chr17_65887536_65887687	0.35	BPTF	bromodomain PHD finger transcription factor	16575	0.18
chr16_6001852_6002003	0.34	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	67168	0.13
chr17_46506355_46506700	0.34	SKAP1	src kinase associated phosphoprotein 1	1025	0.46
chr6_99962436_99962683	0.34	USP45	ubiquitin specific peptidase 45	693	0.65
chr8_98619737_98619888	0.34	MTDH	metadherin	36595	0.21
chr22_22564639_22564790	0.34	IGLV10-54	immunoglobulin lambda variable 10-54	4470	0.09
chr1_59486109_59486451	0.33	JUN	jun proto-oncogene	236495	0.02
chr11_85962410_85962578	0.33	EED	embryonic ectoderm development	6218	0.24
chr12_59309288_59309823	0.33	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	1191	0.55
chr5_56125291_56125578	0.33	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	14033	0.16
chr2_67979592_67979743	0.33	C1D	C1D nuclear receptor corepressor	310447	0.01
chr9_119450477_119450628	0.33	TRIM32	tripartite motif containing 32	930	0.45
chr10_47640402_47640757	0.33	ANTXRLP1	anthrax toxin receptor-like pseudogene 1	4212	0.25
chr13_110972941_110973092	0.33	COL4A2	collagen, type IV, alpha 2	13402	0.21
chr2_184180506_184180887	0.32	NUP35	nucleoporin 35kDa	191523	0.03
chr6_149816889_149817128	0.32	ZC3H12D	zinc finger CCCH-type containing 12D	10811	0.15
chr11_126989829_126989980	0.32	KIRREL3-AS3	KIRREL3 antisense RNA 3	117099	0.06
chrX_106242449_106242662	0.32	MORC4	MORC family CW-type zinc finger 4	753	0.73
chr16_1585013_1585440	0.32	TMEM204	transmembrane protein 204	1652	0.19
chr16_87523020_87523171	0.32	ZCCHC14	zinc finger, CCHC domain containing 14	2556	0.3
chr2_235401709_235401860	0.32	ARL4C	ADP-ribosylation factor-like 4C	3460	0.39
chr4_186063849_186064336	0.32	SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	303	0.9
chr13_99959249_99959863	0.32	GPR183	G protein-coupled receptor 183	103	0.97
chr4_99352135_99352286	0.32	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1	51900	0.15
chr8_22301141_22301459	0.32	PPP3CC	protein phosphatase 3, catalytic subunit, gamma isozyme	2422	0.24
chr1_154317218_154317369	0.32	ENSG00000238365	.	6074	0.11
chr14_23013301_23013513	0.32	AE000662.92	Uncharacterized protein	12127	0.1
chr6_139454805_139454996	0.31	HECA	headcase homolog (Drosophila)	1349	0.54
chr4_122103035_122103186	0.31	ENSG00000252183	.	10948	0.22
chr8_29956030_29956181	0.31	LEPROTL1	leptin receptor overlapping transcript-like 1	2940	0.2
chr5_54795571_54795722	0.31	ENSG00000265135	.	9108	0.22
chr1_246733264_246733547	0.31	CNST	consortin, connexin sorting protein	3589	0.21
chr10_14050350_14050950	0.31	FRMD4A	FERM domain containing 4A	118	0.97
chr16_56658952_56660008	0.31	MT1E	metallothionein 1E	93	0.91
chr11_71750979_71751491	0.31	NUMA1	nuclear mitotic apparatus protein 1	364	0.76
chr11_65324607_65325239	0.31	LTBP3	latent transforming growth factor beta binding protein 3	313	0.76
chr1_241840893_241841044	0.31	WDR64	WD repeat domain 64	5914	0.23
chr6_152622546_152623206	0.31	SYNE1	spectrin repeat containing, nuclear envelope 1	382	0.91
chr19_47689664_47689815	0.31	ENSG00000265134	.	40460	0.1
chr5_118670002_118670187	0.30	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	1224	0.51
chr13_43597427_43597652	0.30	DNAJC15	DnaJ (Hsp40) homolog, subfamily C, member 15	200	0.96
chr18_3252559_3252710	0.30	MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	361	0.84
chr17_54672468_54672763	0.30	NOG	noggin	1555	0.55
chr20_51618499_51618650	0.30	TSHZ2	teashirt zinc finger homeobox 2	29628	0.21
chr2_68693231_68693546	0.30	FBXO48	F-box protein 48	1002	0.45
chr1_111215452_111215765	0.30	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	2047	0.31
chr2_36584985_36585217	0.30	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	1487	0.57
chr11_111249870_111250082	0.30	POU2AF1	POU class 2 associating factor 1	441	0.76
chr16_3240917_3241452	0.30	AJ003147.9		2972	0.13
chr5_112824477_112824726	0.30	MCC	mutated in colorectal cancers	74	0.97
chr12_68043814_68044335	0.29	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	612	0.81
chr17_62654535_62654740	0.29	SMURF2	SMAD specific E3 ubiquitin protein ligase 2	3393	0.27
chr2_74005633_74005961	0.29	DUSP11	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)	1298	0.4
chr10_33404030_33404181	0.29	ENSG00000263576	.	16541	0.23
chr5_159897528_159897679	0.29	ENSG00000265237	.	3806	0.2
chr5_133452450_133452605	0.29	TCF7	transcription factor 7 (T-cell specific, HMG-box)	1211	0.53
chr12_122729504_122729668	0.29	VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)	5126	0.17
chr3_85530941_85531099	0.29	ENSG00000264084	.	96160	0.09
chr14_22978649_22978851	0.29	TRAJ15	T cell receptor alpha joining 15	19830	0.09
chr7_557332_557625	0.29	PDGFA	platelet-derived growth factor alpha polypeptide	667	0.72
chr12_92528873_92529103	0.29	C12orf79	chromosome 12 open reading frame 79	1809	0.33
chr6_144881355_144881717	0.29	UTRN	utrophin	22810	0.28
chr5_61552192_61552373	0.29	KIF2A	kinesin heavy chain member 2A	49707	0.17
chr1_117301810_117301961	0.29	CD2	CD2 molecule	4796	0.25
chr13_48982613_48982764	0.29	LPAR6	lysophosphatidic acid receptor 6	18355	0.26
chr12_27093749_27094602	0.29	FGFR1OP2	FGFR1 oncogene partner 2	2742	0.2
chr18_55981209_55981360	0.29	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	9268	0.23
chr8_24814089_24814240	0.29	CTD-2168K21.2		29	0.98
chr9_131318552_131318703	0.29	SPTAN1	spectrin, alpha, non-erythrocytic 1	3758	0.14
chr4_74107274_74107425	0.29	ANKRD17	ankyrin repeat domain 17	16690	0.18
chr14_23002558_23002709	0.29	TRAJ15	T cell receptor alpha joining 15	4053	0.13
chr6_144671797_144672109	0.29	UTRN	utrophin	6716	0.26
chr6_155492056_155492304	0.28	TIAM2	T-cell lymphoma invasion and metastasis 2	21925	0.23
chr18_48719973_48720133	0.28	MEX3C	mex-3 RNA binding family member C	3076	0.34
chr6_144672449_144672906	0.28	UTRN	utrophin	7440	0.26
chr14_65881266_65881645	0.28	FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	1715	0.46
chr11_3009958_3010109	0.28	NAP1L4	nucleosome assembly protein 1-like 4	356	0.73
chr1_8468525_8468676	0.28	RERE	arginine-glutamic acid dipeptide (RE) repeats	15126	0.18
chr10_33341121_33341272	0.28	ENSG00000265319	.	17344	0.21
chr4_148713676_148713874	0.28	ENSG00000264274	.	10029	0.19
chr6_152621256_152621407	0.28	SYNE1	spectrin repeat containing, nuclear envelope 1	1927	0.44
chr11_122033151_122033302	0.28	ENSG00000207994	.	10210	0.17
chr11_11865444_11865596	0.28	USP47	ubiquitin specific peptidase 47	1907	0.47
chr5_156616823_156617066	0.28	ITK	IL2-inducible T-cell kinase	9107	0.13
chr2_143934651_143934928	0.28	RP11-190J23.1		5048	0.3
chr6_84562741_84563221	0.28	RIPPLY2	ripply transcriptional repressor 2	4	0.98
chr21_26935407_26935596	0.28	ENSG00000234883	.	10791	0.19
chrX_47507821_47507972	0.28	ELK1	ELK1, member of ETS oncogene family	1991	0.22
chr6_106549276_106549427	0.28	RP1-134E15.3		1336	0.46
chr8_59904812_59904963	0.27	RP11-328K2.1		610	0.83
chr14_64912045_64912196	0.27	CTD-2555O16.2		3155	0.15
chr16_78156962_78157154	0.27	WWOX	WW domain containing oxidoreductase	23467	0.22
chr3_150920478_150920863	0.27	GPR171	G protein-coupled receptor 171	309	0.87
chr5_97537777_97537928	0.27	ENSG00000223053	.	437083	0.01
chr12_123559407_123559598	0.27	PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2	1140	0.49
chr17_836954_837239	0.27	RP11-676J12.7	Uncharacterized protein	24224	0.14
chr20_49129722_49130160	0.27	PTPN1	protein tyrosine phosphatase, non-receptor type 1	3021	0.23
chr11_128376572_128377141	0.27	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	1567	0.47
chr5_167492189_167492340	0.27	ENSG00000253065	.	32054	0.2
chr6_143172346_143172497	0.27	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	14237	0.27
chr14_22746989_22747140	0.27	ENSG00000238634	.	136177	0.04
chr8_23075544_23076103	0.27	ENSG00000246582	.	6161	0.12
chr5_91888605_91888788	0.27	ENSG00000264489	.	146952	0.05
chr6_80280696_80280918	0.26	LCA5	Leber congenital amaurosis 5	33632	0.21
chr7_94279148_94279299	0.26	SGCE	sarcoglycan, epsilon	6187	0.22
chr18_55710410_55710839	0.26	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	975	0.64
chr1_25889724_25889930	0.26	LDLRAP1	low density lipoprotein receptor adaptor protein 1	19756	0.18
chr7_142428551_142428702	0.26	PRSS1	protease, serine, 1 (trypsin 1)	28693	0.17
chr14_51271108_51271293	0.26	RP11-286O18.1		17398	0.14
chr17_38018967_38019134	0.26	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1329	0.36
chr12_46846387_46846538	0.26	SLC38A2	solute carrier family 38, member 2	79812	0.1
chrX_74743474_74743629	0.26	ZDHHC15	zinc finger, DHHC-type containing 15	214	0.97
chr12_45269258_45270040	0.26	NELL2	NEL-like 2 (chicken)	54	0.98
chr11_47545712_47545863	0.26	CELF1	CUGBP, Elav-like family member 1	247	0.85
chr6_111801598_111801749	0.26	REV3L	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	2741	0.26
chr1_117453113_117453757	0.26	PTGFRN	prostaglandin F2 receptor inhibitor	756	0.65
chr8_144898551_144898711	0.26	SCRIB	scribbled planar cell polarity protein	1082	0.28
chr12_4384922_4385434	0.26	CCND2	cyclin D2	52	0.65
chrX_100602865_100603061	0.25	TIMM8A	translocase of inner mitochondrial membrane 8 homolog A (yeast)	1221	0.35
chr12_15699122_15699273	0.25	PTPRO	protein tyrosine phosphatase, receptor type, O	89	0.98
chr2_216035977_216036214	0.25	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12	32944	0.21
chr1_19281201_19281537	0.25	IFFO2	intermediate filament family orphan 2	823	0.65
chr10_64966795_64967192	0.25	JMJD1C	jumonji domain containing 1C	492	0.86
chrX_101771933_101772084	0.25	TMSB15A	thymosin beta 15a	296	0.9
chr20_56283633_56283861	0.25	PMEPA1	prostate transmembrane protein, androgen induced 1	1069	0.63
chr13_73355012_73355163	0.25	DIS3	DIS3 mitotic control homolog (S. cerevisiae)	976	0.39
chr1_167483926_167484083	0.25	CD247	CD247 molecule	3771	0.25
chr9_103112844_103112995	0.25	TEX10	testis expressed 10	1934	0.38
chr15_56533717_56534000	0.25	RFX7	regulatory factor X, 7	1606	0.36
chr15_96883153_96883304	0.25	ENSG00000222651	.	6738	0.16
chr9_100682755_100682906	0.25	C9orf156	chromosome 9 open reading frame 156	1939	0.27
chr12_78337025_78337244	0.25	NAV3	neuron navigator 3	22922	0.28
chr12_72054329_72054651	0.25	THAP2	THAP domain containing, apoptosis associated protein 2	2299	0.24
chr21_38352575_38353327	0.25	HLCS	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	23	0.97
chr14_69246908_69247130	0.25	ZFP36L1	ZFP36 ring finger protein-like 1	10941	0.21
chr2_204720302_204720453	0.25	CTLA4	cytotoxic T-lymphocyte-associated protein 4	12132	0.24
chr3_151963057_151963208	0.25	MBNL1	muscleblind-like splicing regulator 1	22697	0.21
chr3_11887290_11887536	0.25	TAMM41	TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)	833	0.74
chr16_71851827_71852052	0.25	AP1G1	adaptor-related protein complex 1, gamma 1 subunit	8835	0.13
chr1_198493106_198493276	0.25	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	16613	0.28
chr14_80678419_80678624	0.25	DIO2	deiodinase, iodothyronine, type II	0	0.95
chr1_38510289_38510696	0.25	POU3F1	POU class 3 homeobox 1	1958	0.27
chr4_48667210_48667361	0.24	FRYL	FRY-like	15903	0.25
chr19_44646557_44646855	0.24	ZNF234	zinc finger protein 234	947	0.4
chr21_35304396_35305066	0.24	LINC00649	long intergenic non-protein coding RNA 649	1213	0.41
chr5_54604876_54605027	0.24	SKIV2L2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	1122	0.39
chr6_42067301_42067452	0.24	C6orf132	chromosome 6 open reading frame 132	42806	0.1
chr17_75451037_75451416	0.24	SEPT9	septin 9	1064	0.46
chr11_18352412_18352563	0.24	GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa	7277	0.13
chr1_39658092_39658302	0.24	MACF1	microtubule-actin crosslinking factor 1	11721	0.17
chr1_204422666_204422817	0.24	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	13733	0.18
chr10_6627878_6628029	0.24	PRKCQ	protein kinase C, theta	5690	0.34
chr5_126205046_126205258	0.24	MARCH3	membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase	48768	0.16
chr10_6628250_6628432	0.24	PRKCQ	protein kinase C, theta	6078	0.33
chr8_126960676_126960849	0.24	ENSG00000206695	.	47567	0.2
chr2_12596554_12597065	0.24	ENSG00000207183	.	45182	0.2
chr6_26152400_26152551	0.24	HIST1H1E	histone cluster 1, H1e	4084	0.08

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.3	0.8	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.2	0.6	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	0.3	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.6	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.6	GO:0010159	specification of organ position(GO:0010159)
0.1	0.7	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.5	GO:0051503	adenine nucleotide transport(GO:0051503)
0.1	0.4	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.1	0.4	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.6	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.9	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.4	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.3	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.2	GO:0060426	lung vasculature development(GO:0060426)
0.1	0.2	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.4	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.1	0.2	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1	0.2	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.2	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.2	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.3	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.2	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.2	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.2	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1	0.2	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.2	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.2	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.2	GO:0001757	somite specification(GO:0001757)
0.1	0.2	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.1	0.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.1	GO:0055026	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1	0.3	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.1	0.5	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.3	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.1	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.1	0.1	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.1	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.4	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.5	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.2	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.4	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.0	0.1	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.6	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.2	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.2	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.3	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.1	GO:0030260	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.3	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.3	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.3	GO:0070875	positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.2	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0048340	paraxial mesoderm morphogenesis(GO:0048340)
0.0	0.8	GO:0006997	nucleus organization(GO:0006997)
0.0	0.1	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.1	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.0	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.2	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0048505	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.1	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.5	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.0	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0046449	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0	0.4	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.0	GO:0048318	axial mesoderm development(GO:0048318) axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.4	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.2	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.2	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.0	GO:0006949	syncytium formation(GO:0006949)
0.0	0.0	GO:0090311	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.0	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.1	GO:0035089	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.3	GO:0010463	mesenchymal cell proliferation(GO:0010463)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.0	GO:0061037	negative regulation of cartilage development(GO:0061037)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.4	GO:0060135	maternal process involved in female pregnancy(GO:0060135)
0.0	0.2	GO:0006577	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0034243	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.0	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.0	GO:0055023	positive regulation of cardiac muscle tissue growth(GO:0055023) positive regulation of cardiac muscle tissue development(GO:0055025) positive regulation of cardiac muscle cell proliferation(GO:0060045)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.2	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:2000051	planar cell polarity pathway involved in axis elongation(GO:0003402) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.3	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.1	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.0	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:1901889	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.0	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0014044	Schwann cell development(GO:0014044)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.0	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.2	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.2	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.0	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.1	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	1.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.0	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.2	GO:0006626	protein targeting to mitochondrion(GO:0006626)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	0.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0005883	neurofilament(GO:0005883)
0.1	0.4	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.4	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.1	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.6	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	1.1	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.3	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.4	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.5	GO:0031674	I band(GO:0031674)
0.0	0.0	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.3	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0001939	female pronucleus(GO:0001939)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0045178	basal part of cell(GO:0045178)
0.0	0.1	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0032806	carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.6	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.5	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	0.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.4	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1	1.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.3	GO:0005113	patched binding(GO:0005113)
0.1	0.3	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.3	GO:0034452	dynactin binding(GO:0034452)
0.1	0.4	GO:0005521	lamin binding(GO:0005521)
0.1	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.5	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.2	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.3	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.4	GO:0046870	cadmium ion binding(GO:0046870)
0.0	1.1	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.4	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.2	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.4	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.6	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0090079	translation activator activity(GO:0008494) translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.4	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0008556	sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.2	GO:0005035	death receptor activity(GO:0005035)
0.0	0.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.2	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.4	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.0	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.0	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.7	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.1	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.6	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.9	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.4	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.3	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.4	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins

Results for TBP

Z-value: 1.77

Motif logo

Transcription factors associated with TBP

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TBP motif across conditions

Conditions sorted by the z-value of the TBP motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: