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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TBX15_MGA

Z-value: 1.48

Motif logo

Transcription factors associated with TBX15_MGA

Gene Symbol	Gene ID	Gene Info
TBX15 Ensembl NCBI GeneCards UniProt	ENSG00000092607.9	TBX15
MGA Ensembl NCBI GeneCards UniProt	ENSG00000174197.12	MGA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
MGA	chr15_41948414_41948565	4121	0.212311	-0.73	2.5e-02	Click!
MGA	chr15_41941188_41941339	11347	0.176664	-0.63	6.9e-02	Click!
MGA	chr15_41896254_41897004	17105	0.155657	-0.63	7.0e-02	Click!
MGA	chr15_41953025_41953321	563	0.750369	0.26	5.0e-01	Click!
MGA	chr15_41913046_41914152	135	0.959821	-0.21	5.8e-01	Click!
TBX15	chr1_119551227_119551389	19129	0.224627	-0.84	4.5e-03	Click!
TBX15	chr1_119521934_119522435	8244	0.279420	-0.83	6.1e-03	Click!
TBX15	chr1_119544408_119544592	12321	0.248066	-0.78	1.4e-02	Click!
TBX15	chr1_119531356_119531507	748	0.757922	-0.75	1.9e-02	Click!
TBX15	chr1_119522601_119522807	7724	0.281427	-0.75	2.0e-02	Click!

Activity of the TBX15_MGA motif across conditions

Conditions sorted by the z-value of the TBX15_MGA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_40599321_40599893	1.32	PLCB2	phospholipase C, beta 2	419	0.68
chr12_109026876_109027027	1.28	SELPLG	selectin P ligand	719	0.55
chr1_202129278_202129681	1.25	PTPN7	protein tyrosine phosphatase, non-receptor type 7	251	0.89
chr1_209930701_209930998	1.24	TRAF3IP3	TRAF3 interacting protein 3	994	0.46
chr6_134598550_134598701	1.24	ENSG00000201309	.	5605	0.2
chr3_183272411_183272703	1.24	KLHL6	kelch-like family member 6	920	0.55
chr19_2289358_2289509	1.23	LINGO3	leucine rich repeat and Ig domain containing 3	2590	0.13
chr2_175498427_175499207	1.23	WIPF1	WAS/WASL interacting protein family, member 1	490	0.83
chr21_15917916_15918619	1.23	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	395	0.89
chr16_31271694_31271922	1.15	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	493	0.67
chr9_117692323_117692779	1.12	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	146	0.98
chr11_2466894_2467127	1.08	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	789	0.56
chr9_95728150_95728303	1.07	FGD3	FYVE, RhoGEF and PH domain containing 3	1983	0.37
chr17_75402240_75402391	1.06	SEPT9	septin 9	1156	0.44
chr1_9689695_9689868	1.04	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	22009	0.15
chr5_169722902_169723053	1.03	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	2254	0.35
chr10_114135452_114136486	1.01	ACSL5	acyl-CoA synthetase long-chain family member 5	12	0.98
chr1_200991352_200991604	0.98	KIF21B	kinesin family member 21B	1058	0.52
chr5_150593261_150593549	0.96	GM2A	GM2 ganglioside activator	1694	0.36
chrX_106957355_106957506	0.94	TSC22D3	TSC22 domain family, member 3	2201	0.37
chr12_94638035_94638186	0.91	PLXNC1	plexin C1	10184	0.18
chr1_174934321_174935265	0.89	RABGAP1L	RAB GTPase activating protein 1-like	888	0.52
chr7_72626118_72626352	0.88	NCF1B	neutrophil cytosolic factor 1B pseudogene	8376	0.18
chr1_28452985_28453161	0.86	ENSG00000253005	.	16279	0.12
chr2_120687736_120687954	0.86	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	493	0.83
chr7_74179826_74180081	0.86	NCF1	neutrophil cytosolic factor 1	8356	0.2
chr6_53199523_53199717	0.85	ELOVL5	ELOVL fatty acid elongase 5	13967	0.2
chr19_42127429_42127580	0.83	CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	5938	0.16
chr2_201989329_201989480	0.83	CFLAR	CASP8 and FADD-like apoptosis regulator	2204	0.22
chr7_74596048_74596381	0.83	GTF2IRD2B	GTF2I repeat domain containing 2B	39310	0.17
chr4_38916539_38916690	0.82	ENSG00000207944	.	46961	0.11
chr10_45870649_45870800	0.82	ALOX5	arachidonate 5-lipoxygenase	1049	0.61
chr1_153917433_153917634	0.82	DENND4B	DENN/MADD domain containing 4B	212	0.86
chr6_106969857_106970345	0.81	AIM1	absent in melanoma 1	10371	0.2
chrX_153191913_153192277	0.81	ARHGAP4	Rho GTPase activating protein 4	116	0.92
chr12_31986615_31986843	0.81	ENSG00000252204	.	22707	0.16
chr1_160615359_160615600	0.80	SLAMF1	signaling lymphocytic activation molecule family member 1	1332	0.39
chr22_37681278_37681429	0.80	CYTH4	cytohesin 4	2825	0.23
chr15_31558914_31559065	0.79	KLF13	Kruppel-like factor 13	60069	0.14
chr16_89830973_89831469	0.78	FANCA	Fanconi anemia, complementation group A	19751	0.11
chr1_244483301_244483484	0.77	C1orf100	chromosome 1 open reading frame 100	32545	0.2
chr19_8567892_8568043	0.77	PRAM1	PML-RARA regulated adaptor molecule 1	29	0.96
chr1_198616268_198616512	0.77	PTPRC	protein tyrosine phosphatase, receptor type, C	8098	0.25
chr15_77306736_77306887	0.76	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	1341	0.45
chr1_153337646_153337797	0.75	S100A9	S100 calcium binding protein A9	7391	0.11
chr7_50728203_50728447	0.75	GRB10	growth factor receptor-bound protein 10	33698	0.21
chr14_21249278_21249626	0.75	RNASE6	ribonuclease, RNase A family, k6	242	0.86
chrX_24497462_24497656	0.75	PDK3	pyruvate dehydrogenase kinase, isozyme 3	13986	0.21
chr7_38398847_38399253	0.74	AMPH	amphiphysin	103663	0.08
chr5_98362367_98362646	0.74	ENSG00000200351	.	90055	0.09
chr19_52149205_52149440	0.74	SIGLEC5	sialic acid binding Ig-like lectin 5	524	0.49
chr14_22320464_22320750	0.73	ENSG00000222776	.	71822	0.11
chr13_24844888_24845461	0.73	SPATA13	spermatogenesis associated 13	195	0.94
chr1_150977368_150977693	0.73	FAM63A	family with sequence similarity 63, member A	1431	0.21
chr9_134147831_134148064	0.72	FAM78A	family with sequence similarity 78, member A	2037	0.3
chr2_233944162_233944358	0.72	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	19071	0.18
chr13_46749322_46749478	0.72	ENSG00000240767	.	5517	0.17
chr22_44391651_44392034	0.72	PARVB	parvin, beta	3249	0.27
chr7_48137698_48137849	0.71	UPP1	uridine phosphorylase 1	8800	0.23
chr16_83840061_83840212	0.71	RP11-483P21.2		404	0.76
chr11_1802236_1802476	0.71	CTSD	cathepsin D	17134	0.08
chr2_24305127_24305278	0.70	TP53I3	tumor protein p53 inducible protein 3	1979	0.21
chr1_173977724_173977875	0.70	RC3H1-IT1	RC3H1 intronic transcript 1 (non-protein coding)	7545	0.17
chr1_212927626_212927881	0.69	NSL1	NSL1, MIS12 kinetochore complex component	37170	0.12
chr16_84634203_84634572	0.69	RP11-61F12.1		6388	0.18
chr14_35870559_35870710	0.69	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	2712	0.36
chr1_36947329_36947542	0.68	CSF3R	colony stimulating factor 3 receptor (granulocyte)	217	0.92
chr3_27922887_27923131	0.68	EOMES	eomesodermin	158803	0.04
chr22_30617296_30617447	0.67	RP3-438O4.4		14273	0.11
chr8_29951661_29951812	0.67	LEPROTL1	leptin receptor overlapping transcript-like 1	1178	0.41
chr19_13213099_13213611	0.67	LYL1	lymphoblastic leukemia derived sequence 1	326	0.79
chr9_134147559_134147710	0.67	FAM78A	family with sequence similarity 78, member A	1724	0.34
chr1_40870751_40870902	0.67	SMAP2	small ArfGAP2	8319	0.17
chr3_177077016_177077315	0.67	ENSG00000252028	.	144175	0.05
chr15_40366035_40366186	0.66	RP11-521C20.3		14923	0.14
chr2_85636540_85636691	0.65	CAPG	capping protein (actin filament), gelsolin-like	340	0.75
chr12_112439883_112440034	0.65	TMEM116	transmembrane protein 116	3831	0.2
chr17_29147256_29147463	0.65	CRLF3	cytokine receptor-like factor 3	4330	0.14
chr1_27669122_27669371	0.65	SYTL1	synaptotagmin-like 1	473	0.71
chr9_36144726_36145049	0.64	GLIPR2	GLI pathogenesis-related 2	8145	0.19
chr5_95156034_95156185	0.64	GLRX	glutaredoxin (thioltransferase)	2306	0.24
chr12_50908112_50908263	0.64	DIP2B	DIP2 disco-interacting protein 2 homolog B (Drosophila)	9297	0.23
chr16_11678677_11678828	0.63	LITAF	lipopolysaccharide-induced TNF factor	1477	0.42
chr20_3994903_3996170	0.63	RNF24	ring finger protein 24	500	0.83
chr22_36831926_36832077	0.63	ENSG00000252575	.	2970	0.21
chr4_40310355_40310513	0.63	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	26912	0.19
chr9_92090917_92091068	0.62	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	3813	0.28
chr3_43298080_43298231	0.62	SNRK	SNF related kinase	29849	0.16
chr17_56406301_56406502	0.61	BZRAP1-AS1	BZRAP1 antisense RNA 1	25	0.76
chr16_90167914_90168065	0.61	PRDM7	PR domain containing 7	25651	0.14
chr3_30683583_30683734	0.61	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	35565	0.21
chr10_75631806_75632024	0.60	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	2304	0.2
chr13_95837800_95837951	0.60	ENSG00000238463	.	24723	0.24
chr12_51720015_51720292	0.60	BIN2	bridging integrator 2	1701	0.31
chr22_26975525_26975744	0.59	TPST2	tyrosylprotein sulfotransferase 2	10455	0.15
chr3_113829556_113829707	0.59	QTRTD1	queuine tRNA-ribosyltransferase domain containing 1	28015	0.17
chr21_34392151_34392837	0.59	OLIG2	oligodendrocyte lineage transcription factor 2	5659	0.22
chr4_87930131_87930308	0.59	AFF1	AF4/FMR2 family, member 1	1798	0.47
chr13_30948639_30948822	0.58	KATNAL1	katanin p60 subunit A-like 1	67109	0.12
chr21_45579276_45579734	0.58	AP001055.1		14075	0.13
chrX_1586224_1586425	0.58	ASMTL	acetylserotonin O-methyltransferase-like	13669	0.19
chr1_6525547_6525781	0.58	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	26	0.96
chr15_90536519_90536670	0.57	ZNF710	zinc finger protein 710	8030	0.15
chr12_26999341_26999492	0.57	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	13285	0.23
chr6_167461487_167461638	0.57	FGFR1OP	FGFR1 oncogene partner	48666	0.1
chrY_1536274_1536425	0.57	NA	NA	> 10⁶	NA
chr19_42391098_42391303	0.56	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	2685	0.17
chr7_28724569_28724720	0.56	CREB5	cAMP responsive element binding protein 5	954	0.73
chr19_1021420_1021571	0.56	ENSG00000207357	.	26	0.83
chr19_36295218_36295369	0.56	PRODH2	proline dehydrogenase (oxidase) 2	2055	0.15
chr18_77442746_77442897	0.56	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	1972	0.4
chr2_192070921_192071072	0.56	MYO1B	myosin IB	38915	0.17
chr7_38389675_38390189	0.56	AMPH	amphiphysin	112781	0.07
chrX_96221078_96221229	0.56	RPA4	replication protein A4, 30kDa	82246	0.11
chr2_102972689_102973095	0.56	IL18R1	interleukin 18 receptor 1	503	0.79
chr17_76168282_76168433	0.56	SYNGR2	synaptogyrin 2	3118	0.14
chr5_175968739_175969051	0.56	CDHR2	cadherin-related family member 2	617	0.6
chr1_12185194_12185345	0.55	TNFRSF8	tumor necrosis factor receptor superfamily, member 8	687	0.66
chr15_41195656_41195807	0.54	VPS18	vacuolar protein sorting 18 homolog (S. cerevisiae)	9066	0.11
chr11_122982090_122982241	0.54	HSPA8	heat shock 70kDa protein 8	48227	0.1
chrY_15863168_15863367	0.54	KALP	Kallmann syndrome sequence pseudogene	269	0.94
chr16_89828290_89828441	0.54	FANCA	Fanconi anemia, complementation group A	16895	0.12
chr16_87542161_87542312	0.54	ZCCHC14	zinc finger, CCHC domain containing 14	16585	0.2
chr10_74084637_74084788	0.53	DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12	20007	0.16
chr19_4431619_4431770	0.53	CTB-50L17.5		763	0.4
chr22_18254644_18254795	0.53	BID	BH3 interacting domain death agonist	2063	0.31
chr7_156801968_156802119	0.53	MNX1	motor neuron and pancreas homeobox 1	62	0.96
chr12_32119532_32119743	0.53	KIAA1551	KIAA1551	4214	0.28
chr11_60870810_60871026	0.53	CD5	CD5 molecule	937	0.56
chr22_36554862_36555013	0.53	APOL3	apolipoprotein L, 3	1894	0.38
chr3_20083173_20083505	0.53	KAT2B	K(lysine) acetyltransferase 2B	1824	0.35
chr2_27110201_27110378	0.53	DPYSL5	dihydropyrimidinase-like 5	38913	0.12
chr2_219228950_219229101	0.53	ENSG00000225062	.	3533	0.11
chrX_70323668_70324217	0.53	CXorf65	chromosome X open reading frame 65	2513	0.16
chr7_142430227_142430392	0.52	PRSS1	protease, serine, 1 (trypsin 1)	27010	0.17
chr1_209849758_209849909	0.52	G0S2	G0/G1switch 2	1068	0.34
chrX_130902480_130902797	0.52	ENSG00000200587	.	170346	0.03
chr6_34283894_34284092	0.52	C6orf1	chromosome 6 open reading frame 1	66746	0.09
chr6_15288185_15288336	0.52	ENSG00000201367	.	26891	0.16
chr15_63783549_63783846	0.52	USP3	ubiquitin specific peptidase 3	13096	0.23
chr1_114323201_114323481	0.51	PHTF1	putative homeodomain transcription factor 1	21243	0.15
chr12_123199893_123200044	0.51	HCAR3	hydroxycarboxylic acid receptor 3	1471	0.32
chr21_32557156_32557409	0.51	TIAM1	T-cell lymphoma invasion and metastasis 1	54743	0.16
chr5_169703125_169703276	0.51	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	8869	0.23
chr7_139467090_139467241	0.51	HIPK2	homeodomain interacting protein kinase 2	10352	0.23
chr3_129630651_129630802	0.51	TMCC1-AS1	TMCC1 antisense RNA 1 (head to head)	10032	0.17
chr14_96593544_96593695	0.51	ENSG00000221236	.	9569	0.19
chr22_40640074_40640407	0.51	TNRC6B	trinucleotide repeat containing 6B	20767	0.22
chr2_233965421_233965586	0.51	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	40314	0.14
chr3_13047785_13047936	0.51	IQSEC1	IQ motif and Sec7 domain 1	19324	0.25
chr8_48515171_48515322	0.51	SPIDR	scaffolding protein involved in DNA repair	56980	0.12
chr6_144461046_144461197	0.50	STX11	syntaxin 11	10542	0.24
chr2_75077032_75077263	0.50	HK2	hexokinase 2	14850	0.24
chr8_142096961_142097112	0.50	DENND3	DENN/MADD domain containing 3	30341	0.17
chr14_102280520_102280788	0.50	CTD-2017C7.2		3996	0.17
chr5_58652913_58653064	0.49	PDE4D	phosphodiesterase 4D, cAMP-specific	187	0.97
chr14_24782112_24782441	0.49	LTB4R	leukotriene B4 receptor	241	0.77
chr1_226920663_226921046	0.49	ITPKB	inositol-trisphosphate 3-kinase B	4305	0.27
chr12_69742009_69742310	0.49	LYZ	lysozyme	5	0.97
chr7_99949902_99950084	0.49	PVRIG2P	poliovirus receptor related immunoglobulin domain containing 2, pseudogene	10	0.49
chr14_62217381_62218261	0.49	SNAPC1	small nuclear RNA activating complex, polypeptide 1, 43kDa	11254	0.25
chr1_112165916_112166067	0.49	RAP1A	RAP1A, member of RAS oncogene family	3222	0.23
chr1_27686628_27686822	0.49	MAP3K6	mitogen-activated protein kinase kinase kinase 6	3717	0.14
chr3_49370394_49370545	0.49	USP4	ubiquitin specific peptidase 4 (proto-oncogene)	6997	0.12
chr6_2855019_2855187	0.49	ENSG00000266750	.	762	0.64
chr6_36259514_36259665	0.48	PNPLA1	patatin-like phospholipase domain containing 1	21352	0.16
chr19_8626043_8626194	0.48	AC092316.1		11728	0.11
chr6_24935630_24936094	0.48	FAM65B	family with sequence similarity 65, member B	326	0.92
chr17_20602116_20602267	0.48	AC126365.1		17605	0.23
chr4_40565848_40565999	0.48	RBM47	RNA binding motif protein 47	47933	0.14
chr2_97590936_97591087	0.48	FAM178B	family with sequence similarity 178, member B	27141	0.12
chr12_113377463_113377923	0.48	OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	1428	0.4
chr20_62271176_62271486	0.47	CTD-3184A7.4		12728	0.09
chr12_1920714_1920865	0.47	CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	97	0.97
chr7_8019798_8019949	0.47	AC006042.7		10339	0.18
chr17_30819432_30819583	0.47	RP11-466A19.1		3047	0.15
chr2_28843114_28843265	0.47	PLB1	phospholipase B1	10264	0.21
chr5_55967386_55967537	0.47	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	65402	0.12
chr2_223643372_223643523	0.47	ENSG00000238852	.	80728	0.08
chr1_160988813_160989129	0.47	F11R	F11 receptor	1915	0.2
chr5_169763562_169763713	0.47	KCNIP1	Kv channel interacting protein 1	16854	0.18
chr22_40299734_40299885	0.47	GRAP2	GRB2-related adaptor protein 2	2696	0.25
chr14_52332461_52332612	0.46	GNG2	guanine nucleotide binding protein (G protein), gamma 2	4494	0.24
chr7_21395262_21395449	0.46	ENSG00000195024	.	25626	0.21
chr17_45297902_45298194	0.46	ENSG00000252088	.	40	0.92
chr17_40427243_40427997	0.46	STAT5B	signal transducer and activator of transcription 5B	804	0.47
chr1_48711225_48711376	0.46	RP5-1024N4.4		16067	0.21
chr1_45196530_45196773	0.46	ENSG00000200169	.	191	0.87
chr3_114014633_114014828	0.46	TIGIT	T cell immunoreceptor with Ig and ITIM domains	896	0.58
chr4_7000592_7000743	0.46	TBC1D14	TBC1 domain family, member 14	243	0.83
chr5_102447212_102447613	0.46	GIN1	gypsy retrotransposon integrase 1	8389	0.23
chr6_12010262_12011396	0.46	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	1404	0.51
chr12_48206617_48206817	0.46	HDAC7	histone deacetylase 7	117	0.96
chr1_200991644_200992373	0.46	KIF21B	kinesin family member 21B	528	0.78
chr22_36848022_36848173	0.45	ENSG00000252225	.	11082	0.14
chr14_70161983_70162134	0.45	SRSF5	serine/arginine-rich splicing factor 5	31559	0.19
chr9_219495_219646	0.45	C9orf66	chromosome 9 open reading frame 66	3677	0.21
chr6_89783524_89783675	0.45	RP11-63L7.5		6787	0.14
chr11_44991792_44991943	0.45	TP53I11	tumor protein p53 inducible protein 11	19259	0.24
chr1_32314203_32314496	0.45	SPOCD1	SPOC domain containing 1	32697	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2	1.0	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.2	0.5	GO:0019372	lipoxygenase pathway(GO:0019372)
0.2	0.8	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.2	0.5	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.4	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1	0.5	GO:0060539	diaphragm development(GO:0060539)
0.1	0.4	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.5	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.7	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.6	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.4	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.4	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.9	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.3	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.1	1.4	GO:0045123	cellular extravasation(GO:0045123)
0.1	0.6	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1	0.3	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.3	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.3	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1	0.1	GO:0061526	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1	0.2	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.1	0.4	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.1	0.3	GO:0034063	stress granule assembly(GO:0034063)
0.1	1.5	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.1	0.2	GO:0003032	detection of oxygen(GO:0003032)
0.1	0.2	GO:0051138	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1	0.1	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	0.2	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1	0.2	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.1	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.1	0.3	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.1	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1	0.1	GO:0002448	mast cell mediated immunity(GO:0002448)
0.1	0.2	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.2	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.7	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.1	0.1	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.1	0.6	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.1	0.3	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.1	0.4	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1	0.2	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0045056	transcytosis(GO:0045056)
0.1	0.3	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.2	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.2	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.1	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.1	0.2	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.3	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.2	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0046629	gamma-delta T cell activation(GO:0046629)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.3	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	1.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.3	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.2	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.3	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.2	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.3	GO:0001562	response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0	0.2	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.7	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.8	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.3	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.6	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.4	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.1	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.3	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.2	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.6	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.2	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.0	GO:0002863	positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.2	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.2	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.2	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.4	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.2	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.4	GO:0016998	cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.6	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.0	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.1	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.1	GO:0060968	regulation of gene silencing(GO:0060968)
0.0	0.3	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0002456	T cell mediated immunity(GO:0002456)
0.0	0.2	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.0	0.3	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.1	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	2.1	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.0	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0033605	positive regulation of catecholamine secretion(GO:0033605)
0.0	0.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.7	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.0	GO:0048302	isotype switching to IgG isotypes(GO:0048291) regulation of isotype switching to IgG isotypes(GO:0048302)
0.0	0.4	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0	0.0	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.5	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.3	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.5	GO:0007602	phototransduction(GO:0007602)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.1	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) regulation of glial cell proliferation(GO:0060251) negative regulation of glial cell proliferation(GO:0060253)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0032608	interferon-beta production(GO:0032608)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.0	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:1901070	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.3	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	1.9	GO:0043087	regulation of GTPase activity(GO:0043087)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0032490	detection of molecule of bacterial origin(GO:0032490)
0.0	0.0	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.3	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.0	GO:0032303	regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0042119	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.3	GO:0019433	triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.5	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.0	GO:0014052	gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.0	0.1	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.0	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.0	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0048246	macrophage chemotaxis(GO:0048246)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.2	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.0	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.3	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.1	GO:0001504	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.2	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.0	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.2	GO:1905037	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.0	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.0	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.0	0.0	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.1	GO:0006026	aminoglycan catabolic process(GO:0006026)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.0	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.2	0.6	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.3	GO:0031904	endosome lumen(GO:0031904)
0.1	0.7	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.7	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	0.8	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.8	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.5	GO:0045179	apical cortex(GO:0045179)
0.1	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.2	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.4	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.3	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	1.0	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	2.8	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	1.0	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	1.0	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0032420	stereocilium(GO:0032420)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.9	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.0	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.7	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0001846	opsonin binding(GO:0001846)
0.2	1.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.2	1.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2	1.2	GO:0005522	profilin binding(GO:0005522)
0.1	0.4	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.5	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.4	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	1.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.4	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	1.0	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1	0.4	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.1	0.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.3	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.4	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.3	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.5	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	0.3	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.8	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.1	0.5	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.6	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.3	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	0.3	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.3	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.7	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.1	1.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.4	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	0.3	GO:0050664	NAD(P)H oxidase activity(GO:0016174) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.5	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.7	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.2	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.2	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.2	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.4	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.3	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.6	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.6	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.4	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	1.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	1.9	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.3	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.3	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.7	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	1.2	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.0	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.2	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.0	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.0	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.6	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0008320	protein transmembrane transporter activity(GO:0008320)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	0.8	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	1.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	0.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	2.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	2.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	0.9	PID EPO PATHWAY	EPO signaling pathway
0.0	0.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.7	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.5	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.9	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.8	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.4	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.5	PID FOXO PATHWAY	FoxO family signaling
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.7	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.9	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.3	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	0.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.1	REACTOME HEMOSTASIS	Genes involved in Hemostasis
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.8	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	0.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.5	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.6	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.7	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.0	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.4	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.0	REACTOME CELL CELL COMMUNICATION	Genes involved in Cell-Cell communication
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.7	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.0	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.0	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.2	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex