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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for TBX21_TBR1

Z-value: 1.61

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Transcription factors associated with TBX21_TBR1

Gene Symbol	Gene ID	Gene Info
TBX21 Ensembl NCBI GeneCards UniProt	ENSG00000073861.2	T-box transcription factor 21
TBR1 Ensembl NCBI GeneCards UniProt	ENSG00000136535.10	T-box brain transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_162275562_162275713	TBR1	1231	0.428706	0.72	3.0e-02	Click!
chr2_162275011_162275548	TBR1	873	0.564371	0.70	3.5e-02	Click!
chr2_162270801_162271071	TBR1	1669	0.333610	0.66	5.3e-02	Click!
chr2_162273183_162273334	TBR1	653	0.682363	0.57	1.1e-01	Click!
chr2_162270607_162270758	TBR1	1923	0.297479	0.55	1.2e-01	Click!
chr17_45812671_45812822	TBX21	2136	0.250156	-0.79	1.1e-02	Click!
chr17_45812120_45812293	TBX21	1596	0.316243	-0.76	1.7e-02	Click!
chr17_45812399_45812645	TBX21	1912	0.272270	-0.76	1.7e-02	Click!
chr17_45812924_45813075	TBX21	2389	0.231216	-0.69	4.0e-02	Click!
chr17_45811310_45811575	TBX21	832	0.550187	-0.63	6.9e-02	Click!

Activity of the TBX21_TBR1 motif across conditions

Conditions sorted by the z-value of the TBX21_TBR1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_121971856_121972438	1.79	RP11-166D19.1		247	0.88
chr4_176922498_176923243	1.71	GPM6A	glycoprotein M6A	613	0.78
chr9_109624062_109624226	1.60	ZNF462	zinc finger protein 462	1234	0.53
chr19_16179581_16179939	1.51	TPM4	tropomyosin 4	1250	0.44
chr6_85472920_85473300	1.43	TBX18	T-box 18	37	0.99
chr6_105388737_105389249	1.42	LIN28B	lin-28 homolog B (C. elegans)	15930	0.23
chr4_169553568_169553728	1.42	PALLD	palladin, cytoskeletal associated protein	880	0.63
chr2_66663569_66663965	1.39	MEIS1	Meis homeobox 1	758	0.57
chr3_100711576_100712203	1.37	ABI3BP	ABI family, member 3 (NESH) binding protein	408	0.89
chr7_100773540_100774051	1.31	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	3416	0.13
chr7_158743544_158743695	1.30	ENSG00000231419	.	57493	0.14
chr4_157890038_157890662	1.28	PDGFC	platelet derived growth factor C	1705	0.41
chr13_40175117_40175459	1.28	LHFP	lipoma HMGIC fusion partner	2020	0.37
chr8_119068765_119068981	1.23	EXT1	exostosin glycosyltransferase 1	53780	0.18
chr1_36104081_36104260	1.23	PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	3275	0.22
chr5_150022452_150022802	1.18	SYNPO	synaptopodin	2387	0.23
chr8_42063953_42065062	1.13	PLAT	plasminogen activator, tissue	576	0.71
chr4_109543923_109544192	1.13	RPL34	ribosomal protein L34	2245	0.3
chr3_119181146_119181418	1.12	TMEM39A	transmembrane protein 39A	1181	0.44
chr2_46928125_46928276	1.11	SOCS5	suppressor of cytokine signaling 5	1874	0.38
chr9_21545267_21545550	1.10	MIR31HG	MIR31 host gene (non-protein coding)	14260	0.16
chr3_98618719_98618976	1.10	DCBLD2	discoidin, CUB and LCCL domain containing 2	1168	0.44
chr2_16832297_16832583	1.09	FAM49A	family with sequence similarity 49, member A	14656	0.3
chr6_28058943_28059326	1.09	ZSCAN12P1	zinc finger and SCAN domain containing 12 pseudogene 1	1071	0.38
chr16_640288_641115	1.07	RAB40C	RAB40C, member RAS oncogene family	369	0.68
chr1_114522595_114522893	1.06	OLFML3	olfactomedin-like 3	49	0.97
chr2_192709104_192709385	1.06	AC098617.1		2021	0.33
chr17_46561109_46561276	1.03	ENSG00000206805	.	4733	0.14
chr8_93074610_93074813	1.03	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	480	0.89
chr21_30503237_30503415	1.01	MAP3K7CL	MAP3K7 C-terminal like	44	0.97
chr4_128553582_128553997	1.01	INTU	inturned planar cell polarity protein	298	0.94
chr1_6803789_6803981	1.00	ENSG00000239166	.	8894	0.17
chr13_45146263_45146555	1.00	TSC22D1	TSC22 domain family, member 1	3983	0.32
chr4_75718841_75720131	0.98	BTC	betacellulin	410	0.91
chr6_27512740_27513343	0.98	ENSG00000206671	.	51150	0.12
chr20_49465299_49465721	0.97	ENSG00000265062	.	11935	0.18
chr2_148394040_148394242	0.96	ENSG00000253083	.	76982	0.1
chr5_167004315_167004466	0.96	CTB-78F1.1		83096	0.1
chr2_203882992_203883167	0.94	NBEAL1	neurobeachin-like 1	3477	0.29
chr3_141087883_141088209	0.93	RP11-438D8.2		2067	0.36
chr12_13408941_13409103	0.92	EMP1	epithelial membrane protein 1	44577	0.17
chr7_121777255_121777586	0.91	AASS	aminoadipate-semialdehyde synthase	3544	0.33
chr10_52835110_52835261	0.91	PRKG1	protein kinase, cGMP-dependent, type I	1251	0.52
chr7_86783544_86783895	0.90	DMTF1	cyclin D binding myb-like transcription factor 1	1772	0.31
chr8_38585652_38586394	0.90	TACC1	transforming, acidic coiled-coil containing protein 1	82	0.97
chr22_43005089_43005553	0.90	POLDIP3	polymerase (DNA-directed), delta interacting protein 3	5542	0.12
chr8_25867876_25868054	0.89	EBF2	early B-cell factor 2	31039	0.24
chr7_100424107_100424380	0.89	EPHB4	EPH receptor B4	494	0.66
chr1_208084062_208084317	0.89	CD34	CD34 molecule	272	0.95
chr2_66802213_66802500	0.89	MEIS1	Meis homeobox 1	66297	0.13
chr5_140857632_140858335	0.88	ENSG00000242020	.	900	0.34
chr4_125632186_125632438	0.88	ANKRD50	ankyrin repeat domain 50	1575	0.58
chr8_141728080_141728633	0.88	PTK2	protein tyrosine kinase 2	98	0.98
chr12_124773798_124773955	0.87	FAM101A	family with sequence similarity 101, member A	166	0.97
chr5_9547291_9547481	0.87	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	1199	0.39
chr10_104465015_104465218	0.87	ARL3	ADP-ribosylation factor-like 3	9048	0.15
chr4_74809740_74810515	0.87	PF4	platelet factor 4	37714	0.11
chr6_28175291_28175856	0.87	ZSCAN9	zinc finger and SCAN domain containing 9	17091	0.12
chr13_51163661_51163984	0.87	DLEU7-AS1	DLEU7 antisense RNA 1	218170	0.02
chr14_85995700_85996361	0.87	FLRT2	fibronectin leucine rich transmembrane protein 2	458	0.75
chr7_83822532_83822694	0.85	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	1604	0.57
chr1_213033781_213033932	0.85	FLVCR1	feline leukemia virus subgroup C cellular receptor 1	1598	0.37
chr1_61668583_61669016	0.85	RP4-802A10.1		78394	0.11
chr1_197885056_197885605	0.85	LHX9	LIM homeobox 9	363	0.9
chr9_21590325_21590604	0.85	MIR31HG	MIR31 host gene (non-protein coding)	30796	0.16
chrX_151142056_151142353	0.84	GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon	939	0.49
chr2_151343410_151343893	0.84	RND3	Rho family GTPase 3	530	0.88
chr15_75943747_75944181	0.84	SNX33	sorting nexin 33	1867	0.18
chr9_36039449_36039608	0.84	RECK	reversion-inducing-cysteine-rich protein with kazal motifs	3098	0.27
chr1_38022972_38023123	0.84	DNALI1	dynein, axonemal, light intermediate chain 1	440	0.76
chr4_57984994_57985389	0.84	IGFBP7	insulin-like growth factor binding protein 7	8640	0.18
chr18_26205812_26205963	0.83	ENSG00000251719	.	422697	0.01
chr3_86843610_86843767	0.82	VGLL3	vestigial like 3 (Drosophila)	196164	0.03
chr5_36744281_36744616	0.82	CTD-2353F22.1		19151	0.27
chr16_3740619_3740949	0.81	TRAP1	TNF receptor-associated protein 1	350	0.86
chr12_15941079_15941239	0.81	EPS8	epidermal growth factor receptor pathway substrate 8	1156	0.62
chr3_25469138_25469713	0.81	RARB	retinoic acid receptor, beta	329	0.93
chr1_197644656_197645195	0.80	ENSG00000207139	.	9945	0.26
chr3_49591196_49591373	0.80	BSN	bassoon presynaptic cytomatrix protein	638	0.69
chr22_36235496_36235773	0.79	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	631	0.82
chrX_67867131_67867291	0.79	STARD8	StAR-related lipid transfer (START) domain containing 8	300	0.94
chr11_33398103_33398382	0.79	ENSG00000223134	.	22231	0.24
chr12_118491012_118491163	0.79	WSB2	WD repeat and SOCS box containing 2	678	0.71
chr2_237570334_237570575	0.79	ACKR3	atypical chemokine receptor 3	92170	0.09
chr14_36538443_36538683	0.78	ENSG00000212071	.	127211	0.05
chr6_17418741_17419244	0.78	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	25049	0.25
chr2_120063785_120064014	0.78	STEAP3-AS1	STEAP3 antisense RNA 1	57252	0.1
chr2_66660959_66661177	0.78	MEIS1-AS3	MEIS1 antisense RNA 3	466	0.7
chr9_21677527_21678485	0.77	ENSG00000244230	.	21307	0.21
chr7_147097205_147097356	0.77	ENSG00000221442	.	22067	0.28
chr12_41086868_41087222	0.77	CNTN1	contactin 1	691	0.81
chr21_17677767_17678526	0.77	ENSG00000201025	.	21057	0.28
chr10_128249841_128250268	0.77	ENSG00000221717	.	4421	0.3
chr7_20391312_20391720	0.77	CTA-293F17.1		20146	0.18
chr11_118851261_118851557	0.77	FOXR1	forkhead box R1	1920	0.13
chr4_77356777_77357012	0.76	SHROOM3	shroom family member 3	641	0.68
chr18_52495652_52496658	0.76	RAB27B	RAB27B, member RAS oncogene family	725	0.77
chr12_59311038_59311457	0.75	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2080	0.36
chr2_238322401_238322657	0.75	COL6A3	collagen, type VI, alpha 3	262	0.93
chr4_186732081_186732288	0.75	SORBS2	sorbin and SH3 domain containing 2	18	0.99
chr20_48601065_48601225	0.75	SNAI1	snail family zinc finger 1	1609	0.33
chr1_120759373_120759544	0.75	RP11-439A17.7		78885	0.08
chr9_94710782_94711296	0.74	ROR2	receptor tyrosine kinase-like orphan receptor 2	123	0.98
chr12_107352268_107352490	0.74	C12orf23	chromosome 12 open reading frame 23	1816	0.3
chr19_37129764_37129915	0.72	ZNF461	zinc finger protein 461	27886	0.11
chr18_9416919_9417231	0.72	RALBP1	ralA binding protein 1	57932	0.1
chr1_27830414_27830820	0.72	WASF2	WAS protein family, member 2	13948	0.16
chr13_109895879_109896348	0.71	MYO16-AS1	MYO16 antisense RNA 1	42282	0.21
chr8_15398260_15398458	0.71	TUSC3	tumor suppressor candidate 3	567	0.83
chr1_51703289_51703476	0.71	RNF11	ring finger protein 11	1439	0.33
chr8_23711040_23711280	0.71	STC1	stanniocalcin 1	664	0.76
chr11_2959849_2960000	0.71	PHLDA2	pleckstrin homology-like domain, family A, member 2	9239	0.12
chr9_125836064_125836223	0.70	MIR600HG	MIR600 host gene (non-protein coding)	37301	0.13
chr4_74847354_74847841	0.70	PF4	platelet factor 4	244	0.89
chr1_110407367_110407518	0.70	RP11-195M16.1		21444	0.16
chr10_114714851_114715858	0.70	RP11-57H14.2		3720	0.26
chrX_139173235_139173445	0.70	ENSG00000241248	.	5326	0.31
chr1_224805949_224806359	0.70	CNIH3	cornichon family AMPA receptor auxiliary protein 3	2159	0.29
chr5_134825154_134825603	0.70	TIFAB	TRAF-interacting protein with forkhead-associated domain, family member B	37289	0.11
chr6_85896028_85896266	0.69	NT5E	5'-nucleotidase, ecto (CD73)	263662	0.02
chr11_94509773_94509974	0.69	AMOTL1	angiomotin like 1	8336	0.24
chr4_187646262_187646501	0.69	FAT1	FAT atypical cadherin 1	1372	0.58
chr6_115106861_115107012	0.69	ENSG00000251882	.	81204	0.12
chr9_118917834_118918063	0.69	PAPPA	pregnancy-associated plasma protein A, pappalysin 1	1865	0.44
chr4_16654215_16654366	0.68	LDB2	LIM domain binding 2	21646	0.28
chr17_15166054_15166259	0.68	PMP22	peripheral myelin protein 22	250	0.88
chr5_63461313_63462499	0.68	RNF180	ring finger protein 180	83	0.99
chr2_218806750_218806920	0.68	TNS1	tensin 1	1958	0.38
chr19_44418412_44418563	0.67	ZNF45	zinc finger protein 45	5404	0.13
chr11_8740394_8740932	0.67	ST5	suppression of tumorigenicity 5	27	0.96
chr7_79693034_79693185	0.67	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	70162	0.13
chr20_50417404_50418104	0.67	SALL4	spalt-like transcription factor 4	1193	0.55
chr3_157248805_157248956	0.67	VEPH1	ventricular zone expressed PH domain-containing 1	2515	0.34
chr8_126322078_126322527	0.67	ENSG00000242170	.	39456	0.16
chrX_45634801_45635003	0.67	ENSG00000207725	.	28372	0.2
chr2_200322083_200322803	0.67	SATB2-AS1	SATB2 antisense RNA 1	20	0.87
chr15_57353400_57353551	0.67	ENSG00000222586	.	94880	0.08
chr2_162275011_162275548	0.67	TBR1	T-box, brain, 1	873	0.56
chr3_126702505_126703684	0.67	PLXNA1	plexin A1	4343	0.34
chr9_113507489_113507640	0.66	MUSK	muscle, skeletal, receptor tyrosine kinase	30063	0.23
chr1_19890223_19890459	0.66	ENSG00000239027	.	31573	0.11
chr1_110693132_110693795	0.66	SLC6A17	solute carrier family 6 (neutral amino acid transporter), member 17	355	0.81
chr4_160188761_160189259	0.66	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	121	0.97
chr5_52333250_52333558	0.66	CTD-2175A23.1		47296	0.12
chr16_69139287_69139438	0.65	HAS3	hyaluronan synthase 3	105	0.96
chr8_48675603_48675928	0.65	PRKDC	protein kinase, DNA-activated, catalytic polypeptide	15333	0.17
chr19_19574756_19575086	0.65	GATAD2A	GATA zinc finger domain containing 2A	570	0.67
chr9_130615331_130615482	0.65	ENG	endoglin	1509	0.19
chr9_31137552_31137738	0.65	ENSG00000211510	.	363419	0.01
chr1_179111876_179112093	0.65	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	195	0.95
chr15_96886136_96886425	0.64	ENSG00000222651	.	9790	0.16
chr3_87036535_87037613	0.64	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr10_97033801_97033952	0.64	PDLIM1	PDZ and LIM domain 1	16905	0.21
chr4_141217305_141217524	0.64	ENSG00000252300	.	21148	0.19
chr2_219471971_219472122	0.64	PLCD4	phospholipase C, delta 4	442	0.69
chr11_10003518_10003874	0.64	SBF2	SET binding factor 2	10955	0.27
chr1_15297301_15297452	0.64	KAZN	kazrin, periplakin interacting protein	24961	0.26
chr12_8025289_8025834	0.64	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	49	0.96
chr9_91795522_91795714	0.64	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	1936	0.42
chrX_114467670_114468385	0.64	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	601	0.77
chr9_21558481_21558945	0.64	MIR31HG	MIR31 host gene (non-protein coding)	955	0.56
chr20_30149403_30149560	0.64	HM13-IT1	HM13 intronic transcript 1 (non-protein coding)	1488	0.28
chr5_58592476_58593460	0.64	PDE4D	phosphodiesterase 4D, cAMP-specific	21023	0.29
chr9_139332087_139332440	0.63	INPP5E	inositol polyphosphate-5-phosphatase, 72 kDa	2011	0.19
chr16_51187260_51187547	0.63	SALL1	spalt-like transcription factor 1	2217	0.35
chr13_60737053_60737204	0.63	DIAPH3	diaphanous-related formin 3	772	0.67
chrX_19687578_19687729	0.63	SH3KBP1	SH3-domain kinase binding protein 1	827	0.76
chr10_115234752_115234903	0.63	HABP2	hyaluronan binding protein 2	75769	0.11
chr9_16522317_16522568	0.63	RP11-183I6.2		49256	0.17
chr3_99363047_99363203	0.63	COL8A1	collagen, type VIII, alpha 1	5671	0.29
chr3_157157796_157157947	0.63	PTX3	pentraxin 3, long	3293	0.33
chr1_154785958_154786192	0.63	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	46244	0.11
chr2_209118562_209118713	0.62	IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	409	0.73
chr2_216288358_216288696	0.62	FN1	fibronectin 1	12263	0.21
chr5_97644935_97645160	0.62	ENSG00000223053	.	329888	0.01
chr2_65804604_65804761	0.62	ENSG00000251900	.	22014	0.21
chr3_112358063_112358400	0.61	CCDC80	coiled-coil domain containing 80	1287	0.54
chr17_37856067_37857084	0.61	ERBB2	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2	242	0.86
chr5_115313493_115313761	0.61	AQPEP	Aminopeptidase Q	15436	0.17
chr4_20256931_20257082	0.61	SLIT2	slit homolog 2 (Drosophila)	463	0.9
chr14_105439152_105439360	0.61	AHNAK2	AHNAK nucleoprotein 2	5438	0.17
chr17_65427494_65427948	0.61	ENSG00000201547	.	22724	0.12
chr3_11679694_11679904	0.61	VGLL4	vestigial like 4 (Drosophila)	5599	0.23
chr19_13107353_13108160	0.61	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1104	0.3
chr2_175197566_175197717	0.61	SP9	Sp9 transcription factor	2033	0.28
chr18_52968140_52968291	0.60	TCF4	transcription factor 4	1642	0.52
chr9_21558261_21558438	0.60	MIR31HG	MIR31 host gene (non-protein coding)	1319	0.44
chr6_75992353_75992507	0.60	TMEM30A	transmembrane protein 30A	1597	0.4
chr11_128774649_128775076	0.60	C11orf45	chromosome 11 open reading frame 45	730	0.63
chr8_38030618_38031135	0.60	BAG4	BCL2-associated athanogene 4	3230	0.13
chr2_46526745_46526934	0.60	EPAS1	endothelial PAS domain protein 1	2298	0.41
chr19_47735595_47736220	0.60	BBC3	BCL2 binding component 3	116	0.95
chr20_6748611_6748844	0.60	BMP2	bone morphogenetic protein 2	416	0.91
chr6_125209841_125210256	0.59	RNF217	ring finger protein 217	73643	0.12
chr16_29836314_29836619	0.59	MVP	major vault protein	3820	0.08
chr3_99357829_99358140	0.59	COL8A1	collagen, type VIII, alpha 1	530	0.85
chr14_45433529_45433743	0.59	FAM179B	family with sequence similarity 179, member B	2194	0.25
chrX_10587548_10588615	0.59	MID1	midline 1 (Opitz/BBB syndrome)	378	0.91
chr7_15503276_15503427	0.59	AGMO	alkylglycerol monooxygenase	97504	0.09
chr4_111454620_111454933	0.59	RP11-380D23.1		14115	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.4	1.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.3	1.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	0.6	GO:0060594	mammary gland specification(GO:0060594)
0.3	1.4	GO:0060206	estrous cycle phase(GO:0060206)
0.2	0.7	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.2	0.9	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.9	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	0.7	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.2	0.6	GO:0060437	lung growth(GO:0060437)
0.2	0.4	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.2	0.4	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.2	0.8	GO:0060174	limb bud formation(GO:0060174)
0.2	0.6	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.2	0.4	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2	0.6	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2	0.6	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2	0.7	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2	0.7	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2	0.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.2	0.5	GO:0010159	specification of organ position(GO:0010159)
0.2	0.5	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.2	0.7	GO:0070141	response to UV-A(GO:0070141)
0.2	0.5	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2	0.5	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.6	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1	0.9	GO:0032288	myelin assembly(GO:0032288)
0.1	0.6	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.6	GO:0010664	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.7	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.1	0.3	GO:0001705	ectoderm formation(GO:0001705)
0.1	0.2	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.5	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.4	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.8	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.7	GO:0071320	cellular response to cAMP(GO:0071320)
0.1	1.5	GO:0035329	hippo signaling(GO:0035329)
0.1	0.3	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.3	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.3	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.3	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.3	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.1	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.1	GO:0031054	pre-miRNA processing(GO:0031054)
0.1	0.7	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.5	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.2	GO:0060841	venous blood vessel development(GO:0060841)
0.1	0.9	GO:0000052	citrulline metabolic process(GO:0000052)
0.1	0.6	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.5	GO:0006102	isocitrate metabolic process(GO:0006102)
0.1	0.5	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.2	GO:0070254	mucus secretion(GO:0070254)
0.1	0.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.1	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.4	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.3	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.4	GO:0060119	inner ear receptor cell development(GO:0060119) inner ear receptor stereocilium organization(GO:0060122)
0.1	0.2	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.2	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1	1.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.1	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.2	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.1	0.5	GO:0060438	trachea development(GO:0060438)
0.1	0.3	GO:0051014	actin filament severing(GO:0051014)
0.1	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.3	GO:0001554	luteolysis(GO:0001554)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.3	GO:0019695	choline metabolic process(GO:0019695)
0.1	0.4	GO:0008228	opsonization(GO:0008228)
0.1	0.2	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.7	GO:0002066	columnar/cuboidal epithelial cell development(GO:0002066)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.6	GO:0060323	head morphogenesis(GO:0060323)
0.1	0.1	GO:0030202	heparin metabolic process(GO:0030202)
0.1	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.2	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	1.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.2	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.2	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.1	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.1	1.8	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.2	GO:0046084	purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1	0.3	GO:0016322	neuron remodeling(GO:0016322)
0.1	0.1	GO:0043084	penile erection(GO:0043084)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.2	GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1	0.2	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1	0.2	GO:0051153	regulation of striated muscle cell differentiation(GO:0051153)
0.1	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	1.3	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:1905209	positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.1	0.2	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.2	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.4	GO:0031000	response to caffeine(GO:0031000)
0.1	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.3	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.4	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.4	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.5	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.1	GO:2000095	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.1	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.5	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.2	GO:0032909	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1	0.6	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.1	0.3	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1	0.9	GO:0007340	acrosome reaction(GO:0007340)
0.1	0.1	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1	0.1	GO:0045079	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.3	GO:0033483	gas homeostasis(GO:0033483)
0.1	1.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.9	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.7	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.6	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.3	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.3	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.2	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0	0.2	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.3	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.2	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.0	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.0	GO:0046880	regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.3	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.5	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0031223	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0	0.2	GO:0060180	regulation of female receptivity(GO:0045924) female mating behavior(GO:0060180)
0.0	0.8	GO:0046068	cGMP metabolic process(GO:0046068)
0.0	0.3	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.0	GO:0060123	regulation of growth hormone secretion(GO:0060123) positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.7	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.2	GO:0010955	negative regulation of protein processing(GO:0010955) negative regulation of complement activation(GO:0045916) negative regulation of protein maturation(GO:1903318) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0035137	hindlimb morphogenesis(GO:0035137)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.4	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.2	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.0	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	1.0	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.3	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0003160	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.3	GO:0007431	salivary gland development(GO:0007431)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.6	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592) mammary placode formation(GO:0060596)
0.0	0.0	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.9	GO:1990138	axon extension(GO:0048675) neuron projection extension(GO:1990138)
0.0	0.2	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0061037	negative regulation of cartilage development(GO:0061037)
0.0	0.1	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.1	GO:0014044	Schwann cell development(GO:0014044)
0.0	0.7	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.5	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.5	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.1	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.1	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.4	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.5	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.9	GO:0030509	BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0	0.1	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.3	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.1	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.4	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:0060442	branching involved in prostate gland morphogenesis(GO:0060442)
0.0	0.1	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0051963	regulation of synapse assembly(GO:0051963)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.2	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.0	GO:0044253	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.5	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.5	GO:0007043	cell-cell junction assembly(GO:0007043)
0.0	0.1	GO:0034105	positive regulation of tissue remodeling(GO:0034105)
0.0	0.2	GO:0015695	organic cation transport(GO:0015695)
0.0	0.4	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.0	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	2.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.2	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.0	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.0	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.0	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0060350	endochondral bone morphogenesis(GO:0060350)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0090398	cellular senescence(GO:0090398)
0.0	0.1	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0	0.0	GO:0060039	pericardium development(GO:0060039)
0.0	0.1	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.2	GO:0050931	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0	0.0	GO:0044266	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.6	GO:0008584	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.7	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.0	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0000097	sulfur amino acid biosynthetic process(GO:0000097)
0.0	0.2	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0048821	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0060004	reflex(GO:0060004)
0.0	0.0	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.1	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.1	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.5	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.0	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.3	GO:0030336	negative regulation of cell migration(GO:0030336) negative regulation of cell motility(GO:2000146)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0044319	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.2	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.0	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.0	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0098876	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.3	GO:0051216	cartilage development(GO:0051216)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0040013	negative regulation of locomotion(GO:0040013)
0.0	0.4	GO:0070252	actin-mediated cell contraction(GO:0070252)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0048705	skeletal system morphogenesis(GO:0048705)
0.0	0.3	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.0	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.1	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.0	0.0	GO:0019236	response to pheromone(GO:0019236)
0.0	0.0	GO:0070230	positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234)
0.0	0.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.0	GO:0015800	acidic amino acid transport(GO:0015800)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.0	GO:0010155	regulation of proton transport(GO:0010155)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.7	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.8	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.8	GO:0043218	compact myelin(GO:0043218)
0.2	0.6	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.4	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.9	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.4	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.9	GO:0005916	fascia adherens(GO:0005916)
0.1	0.6	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.3	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	0.6	GO:0030673	axolemma(GO:0030673)
0.1	0.7	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.8	GO:0008091	spectrin(GO:0008091)
0.1	0.5	GO:0010369	chromocenter(GO:0010369)
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.2	GO:0071437	invadopodium(GO:0071437)
0.1	0.4	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.9	GO:0005858	axonemal dynein complex(GO:0005858)
0.1	0.3	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.9	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.7	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.0	GO:0016011	dystroglycan complex(GO:0016011)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	1.2	GO:0030018	Z disc(GO:0030018)
0.0	4.4	GO:0005925	focal adhesion(GO:0005925)
0.0	3.0	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.7	GO:0005581	collagen trimer(GO:0005581)
0.0	0.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.9	GO:0043197	dendritic spine(GO:0043197)
0.0	0.3	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.4	GO:0005912	adherens junction(GO:0005912)
0.0	2.0	GO:0031091	platelet alpha granule(GO:0031091)
0.0	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	1.5	GO:0030426	growth cone(GO:0030426)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.4	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	5.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.3	GO:0043195	terminal bouton(GO:0043195)
0.0	3.0	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	1.3	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	0.0	GO:0044447	axoneme part(GO:0044447)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.4	GO:0030286	dynein complex(GO:0030286)
0.0	0.6	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.7	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.2	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.7	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0043189	H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0070069	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) cytochrome complex(GO:0070069)
0.0	0.4	GO:0030017	sarcomere(GO:0030017)
0.0	0.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.5	1.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	1.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	0.8	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	0.7	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	0.9	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.6	GO:0016362	activin receptor activity, type II(GO:0016362)
0.2	1.0	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	1.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	0.5	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.2	0.6	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.6	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	1.0	GO:0017166	vinculin binding(GO:0017166)
0.1	1.4	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.8	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	1.0	GO:0048185	activin binding(GO:0048185)
0.1	0.4	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.6	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	0.4	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.3	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.4	GO:0030172	troponin C binding(GO:0030172)
0.1	0.3	GO:0005113	patched binding(GO:0005113)
0.1	0.5	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.1	0.6	GO:0030507	spectrin binding(GO:0030507)
0.1	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.3	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.8	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.3	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.2	GO:0004104	cholinesterase activity(GO:0004104)
0.1	0.8	GO:0005523	tropomyosin binding(GO:0005523)
0.1	2.9	GO:0005518	collagen binding(GO:0005518)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	1.1	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.1	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.7	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.2	GO:0042805	actinin binding(GO:0042805)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.5	GO:0044548	S100 protein binding(GO:0044548)
0.1	1.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.7	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.2	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.8	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	1.3	GO:0005109	frizzled binding(GO:0005109)
0.1	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.6	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.3	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.1	0.7	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	1.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.6	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	0.2	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.1	GO:0032052	bile acid binding(GO:0032052)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.9	GO:0016917	GABA receptor activity(GO:0016917)
0.1	0.3	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1	0.6	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0015149	hexose transmembrane transporter activity(GO:0015149)
0.0	0.4	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.3	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.3	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.6	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.7	GO:0045296	cadherin binding(GO:0045296)
0.0	0.5	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.3	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	2.0	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.7	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.4	GO:0030553	cGMP binding(GO:0030553)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.5	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.9	GO:0019003	GDP binding(GO:0019003)
0.0	0.5	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.2	GO:0016208	AMP binding(GO:0016208)
0.0	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.8	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.6	GO:0017022	myosin binding(GO:0017022)
0.0	1.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.8	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.7	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.4	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.4	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	1.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	6.0	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.2	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.0	GO:0031432	titin binding(GO:0031432)
0.0	1.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.3	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	1.7	GO:0008083	growth factor activity(GO:0008083)
0.0	0.0	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.0	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) alkane 1-monooxygenase activity(GO:0018685)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.2	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.0	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.7	GO:0004497	monooxygenase activity(GO:0004497)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	3.4	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	1.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	2.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	1.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.8	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.9	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.1	PID BMP PATHWAY	BMP receptor signaling
0.0	0.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	4.2	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	5.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.2	1.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.3	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	1.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.1	1.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	2.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.1	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1	0.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	4.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	2.1	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.5	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	0.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.1	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	0.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	1.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.0	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.0	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.7	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones

Results for TBX21_TBR1

Z-value: 1.61

Motif logo

Transcription factors associated with TBX21_TBR1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TBX21_TBR1 motif across conditions

Conditions sorted by the z-value of the TBX21_TBR1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: