Project

ENCODE: H3K4me3 ChIP-Seq of primary human cells

Navigation

Downloads

Results for TBX3

Z-value: 1.99

Motif logo

Transcription factors associated with TBX3

Gene Symbol	Gene ID	Gene Info
TBX3 Ensembl NCBI GeneCards UniProt	ENSG00000135111.10	T-box transcription factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_115122776_115122995	TBX3	916	0.637157	-0.88	1.8e-03	Click!
chr12_115121993_115122268	TBX3	161	0.963569	-0.77	1.6e-02	Click!
chr12_115121649_115121819	TBX3	235	0.943089	-0.77	1.6e-02	Click!
chr12_115120620_115120912	TBX3	629	0.767663	-0.74	2.3e-02	Click!
chr12_115109284_115109435	TBX3	12036	0.211623	-0.72	2.9e-02	Click!

Activity of the TBX3 motif across conditions

Conditions sorted by the z-value of the TBX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_81591495_81592151	0.74	IL16	interleukin 16	66	0.98
chr9_35489468_35490886	0.58	RUSC2	RUN and SH3 domain containing 2	53	0.97
chr19_42701262_42701413	0.57	ENSG00000265122	.	4107	0.11
chr10_114135452_114136486	0.56	ACSL5	acyl-CoA synthetase long-chain family member 5	12	0.98
chr19_7743254_7743405	0.56	CTD-3214H19.16		58	0.92
chrX_65237583_65237734	0.53	ENSG00000207939	.	1054	0.55
chrX_1653880_1654070	0.53	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	2025	0.36
chrY_1603880_1604065	0.53	NA	NA	> 10⁶	NA
chr13_75344161_75344312	0.52	ENSG00000206812	.	339488	0.01
chr14_101034010_101035263	0.51	BEGAIN	brain-enriched guanylate kinase-associated	192	0.93
chr1_169679248_169679951	0.51	SELL	selectin L	1240	0.48
chr13_113344762_113345507	0.50	ATP11A	ATPase, class VI, type 11A	491	0.81
chr12_15110903_15111342	0.50	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	3078	0.22
chr6_17600619_17601800	0.50	FAM8A1	family with sequence similarity 8, member A1	623	0.76
chr12_109796152_109796561	0.49	MYO1H	myosin IH	10648	0.21
chr20_30650243_30650634	0.48	HCK	hemopoietic cell kinase	10374	0.12
chr19_2083107_2083981	0.47	MOB3A	MOB kinase activator 3A	1847	0.21
chr19_54881402_54882266	0.47	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	224	0.88
chr19_39825870_39826313	0.45	GMFG	glia maturation factor, gamma	554	0.58
chr1_245215310_245215673	0.45	ENSG00000251754	.	8261	0.17
chr14_75742225_75742376	0.45	FOS	FBJ murine osteosarcoma viral oncogene homolog	3177	0.2
chr16_29838328_29838548	0.44	MVP	major vault protein	2495	0.1
chr1_193451825_193451976	0.44	ENSG00000252241	.	249174	0.02
chr2_178259623_178259774	0.43	AGPS	alkylglycerone phosphate synthase	2202	0.2
chr2_169961988_169962139	0.43	AC007556.3		4810	0.25
chr9_273119_273416	0.42	DOCK8	dedicator of cytokinesis 8	197	0.59
chrX_128914916_128915218	0.42	SASH3	SAM and SH3 domain containing 3	1107	0.52
chr2_96814743_96814894	0.42	DUSP2	dual specificity phosphatase 2	3639	0.19
chr15_55695695_55695873	0.42	CCPG1	cell cycle progression 1	4466	0.19
chr18_9701912_9702261	0.41	RAB31	RAB31, member RAS oncogene family	6076	0.24
chr5_39274254_39274635	0.41	FYB	FYN binding protein	186	0.97
chr22_18597024_18597175	0.41	TUBA8	tubulin, alpha 8	3540	0.2
chr6_170461369_170461520	0.40	RP11-302L19.1		16297	0.25
chr20_4795121_4795462	0.40	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	478	0.82
chr5_43039425_43040424	0.40	AC025171.1		1753	0.28
chr6_24858784_24858989	0.39	ENSG00000263391	.	18593	0.17
chr8_68304896_68305241	0.39	ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	49156	0.18
chr4_140992108_140992259	0.38	RP11-392B6.1		56986	0.14
chr2_114019245_114019396	0.37	ENSG00000189223	.	6354	0.17
chr11_58989802_58989953	0.37	ENSG00000263999	.	7705	0.17
chrX_48910717_48911936	0.37	CCDC120	coiled-coil domain containing 120	225	0.85
chr12_11924132_11924283	0.37	ETV6	ets variant 6	18772	0.27
chr4_65889717_65889868	0.37	TECRL	trans-2,3-enoyl-CoA reductase-like	614606	0.0
chr2_191914732_191914993	0.36	ENSG00000231858	.	28610	0.15
chr16_29756930_29757303	0.36	C16orf54	chromosome 16 open reading frame 54	211	0.73
chr7_67384045_67384316	0.36	ENSG00000265600	.	562513	0.0
chr20_10771075_10771226	0.36	RP11-103J8.1		111782	0.07
chr2_136871999_136872150	0.36	CXCR4	chemokine (C-X-C motif) receptor 4	1739	0.49
chr10_130019308_130019459	0.36	MKI67	marker of proliferation Ki-67	94734	0.09
chr3_142841963_142842114	0.36	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	3865	0.28
chr16_12927774_12927925	0.36	ENSG00000199474	.	8618	0.2
chr8_144766497_144767420	0.35	ZNF707	zinc finger protein 707	280	0.78
chr16_31271922_31272073	0.35	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	682	0.53
chr11_2322790_2323148	0.35	C11orf21	chromosome 11 open reading frame 21	174	0.62
chr15_96422321_96422472	0.35	ENSG00000222076	.	133363	0.06
chrX_106873865_106874016	0.35	PRPS1	phosphoribosyl pyrophosphate synthetase 1	2147	0.39
chr20_1472149_1472300	0.35	SIRPB2	signal-regulatory protein beta 2	97	0.95
chr1_202131086_202131237	0.34	PTPN7	protein tyrosine phosphatase, non-receptor type 7	445	0.77
chr1_15489874_15490025	0.34	C1orf195	chromosome 1 open reading frame 195	7825	0.21
chr5_149790034_149790185	0.34	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	2186	0.28
chr6_6717439_6717590	0.34	LY86-AS1	LY86 antisense RNA 1	94510	0.09
chrX_70277798_70278092	0.34	SNX12	sorting nexin 12	10308	0.13
chr8_16240155_16240306	0.34	MSR1	macrophage scavenger receptor 1	167647	0.04
chr5_77805493_77806187	0.34	LHFPL2	lipoma HMGIC fusion partner-like 2	39134	0.21
chr14_39593348_39593499	0.34	GEMIN2	gem (nuclear organelle) associated protein 2	9442	0.18
chr2_7019418_7019658	0.34	RSAD2	radical S-adenosyl methionine domain containing 2	613	0.71
chr5_131793521_131793672	0.34	ENSG00000202533	.	10243	0.13
chr9_92220501_92221395	0.34	GADD45G	growth arrest and DNA-damage-inducible, gamma	995	0.69
chr19_44988600_44988751	0.33	ZNF180	zinc finger protein 180	15887	0.16
chr2_64440045_64440196	0.33	AC074289.1		6011	0.28
chr1_114324691_114324842	0.33	PHTF1	putative homeodomain transcription factor 1	22668	0.15
chr10_69146560_69146778	0.33	CTNNA3	catenin (cadherin-associated protein), alpha 3	206468	0.03
chr8_38663016_38663332	0.33	TACC1	transforming, acidic coiled-coil containing protein 1	206	0.93
chr12_6250478_6250629	0.33	VWF	von Willebrand factor	16712	0.18
chr10_6622430_6623103	0.33	PRKCQ	protein kinase C, theta	503	0.89
chr1_182354755_182354906	0.33	GLUL	glutamate-ammonia ligase	5709	0.22
chr20_1600502_1600653	0.33	SIRPB1	signal-regulatory protein beta 1	65	0.51
chr7_26333293_26333815	0.33	SNX10	sorting nexin 10	880	0.67
chr1_150975096_150975673	0.33	FAM63A	family with sequence similarity 63, member A	3577	0.1
chr22_28064722_28064873	0.33	RP11-375H17.1		47671	0.19
chrX_153978145_153979054	0.33	GAB3	GRB2-associated binding protein 3	733	0.55
chr11_134101726_134101877	0.32	NCAPD3	non-SMC condensin II complex, subunit D3	6453	0.15
chr19_13906290_13907522	0.32	ZSWIM4	zinc finger, SWIM-type containing 4	632	0.39
chr10_25836306_25836457	0.32	ENSG00000222543	.	153608	0.04
chr10_6243545_6244657	0.32	RP11-414H17.5		555	0.52
chr4_38805812_38806064	0.32	TLR1	toll-like receptor 1	59	0.97
chr17_29645805_29646348	0.32	CTD-2370N5.3		227	0.88
chr11_33921933_33922084	0.32	LMO2	LIM domain only 2 (rhombotin-like 1)	8172	0.22
chr10_11221601_11222262	0.32	RP3-323N1.2		8592	0.22
chr2_75077658_75077809	0.32	HK2	hexokinase 2	15436	0.24
chr19_30911047_30911198	0.32	ZNF536	zinc finger protein 536	47803	0.19
chr12_68762477_68762628	0.32	MDM1	Mdm1 nuclear protein homolog (mouse)	36391	0.2
chr1_236080766_236080917	0.32	ENSG00000206803	.	2126	0.32
chr19_57348707_57348905	0.32	ZIM2	zinc finger, imprinted 2	1360	0.41
chr9_132220609_132220886	0.32	ENSG00000264298	.	20088	0.2
chr2_8617409_8617560	0.32	AC011747.7		198412	0.03
chr4_15659797_15659948	0.31	FBXL5	F-box and leucine-rich repeat protein 5	1615	0.4
chr3_46973287_46973623	0.31	PTH1R	parathyroid hormone 1 receptor	29366	0.12
chr1_112159044_112159195	0.31	RAP1A	RAP1A, member of RAS oncogene family	3280	0.23
chr1_174937685_174937958	0.31	RABGAP1L	RAB GTPase activating protein 1-like	3916	0.18
chr16_54085316_54085467	0.31	RP11-357N13.1		3104	0.26
chr12_66635842_66635993	0.31	ENSG00000266539	.	6515	0.17
chr19_55084758_55085279	0.31	LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	200	0.63
chr1_31228309_31228562	0.31	LAPTM5	lysosomal protein transmembrane 5	2232	0.26
chr14_22694848_22695133	0.31	ENSG00000238634	.	84103	0.09
chr14_52350730_52351013	0.31	GNG2	guanine nucleotide binding protein (G protein), gamma 2	6561	0.21
chr13_50706829_50707141	0.30	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	50678	0.13
chr13_28996805_28996956	0.30	FLT1	fms-related tyrosine kinase 1	72352	0.12
chr21_15917916_15918619	0.30	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	395	0.89
chr16_12667643_12667794	0.30	CTD-3037G24.4		16167	0.18
chr9_108006382_108006838	0.30	SLC44A1	solute carrier family 44 (choline transporter), member 1	293	0.95
chr3_10283865_10284016	0.30	TATDN2	TatD DNase domain containing 2	5767	0.14
chr22_24541973_24542126	0.30	CABIN1	calcineurin binding protein 1	9757	0.17
chr12_123714056_123714279	0.30	MPHOSPH9	M-phase phosphoprotein 9	826	0.5
chr8_61741074_61741225	0.30	RP11-33I11.2		18984	0.27
chr1_179923890_179924704	0.30	CEP350	centrosomal protein 350kDa	389	0.87
chr17_4882342_4882493	0.30	RP5-1050D4.2		6271	0.06
chr13_37666498_37666649	0.30	CSNK1A1L	casein kinase 1, alpha 1-like	13230	0.19
chr5_76114529_76115764	0.30	F2RL1	coagulation factor II (thrombin) receptor-like 1	344	0.86
chr8_104348979_104349167	0.30	CTHRC1	collagen triple helix repeat containing 1	34670	0.12
chr4_166221472_166221623	0.30	MSMO1	methylsterol monooxygenase 1	27228	0.16
chr16_28152103_28152254	0.30	XPO6	exportin 6	28967	0.15
chr18_21598879_21599226	0.30	TTC39C	tetratricopeptide repeat domain 39C	2454	0.25
chr2_68639075_68639226	0.30	AC015969.3		46434	0.11
chr2_143911804_143911955	0.29	RP11-190J23.1		17862	0.23
chr11_117858339_117858806	0.29	IL10RA	interleukin 10 receptor, alpha	1463	0.41
chr2_175460831_175461348	0.29	WIPF1	WAS/WASL interacting protein family, member 1	1404	0.41
chr7_50797821_50797972	0.29	GRB10	growth factor receptor-bound protein 10	2154	0.45
chr13_30950425_30950835	0.29	KATNAL1	katanin p60 subunit A-like 1	69009	0.11
chr5_169718271_169718661	0.29	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	6765	0.24
chrX_3629951_3631442	0.29	PRKX	protein kinase, X-linked	953	0.63
chr17_1613403_1614190	0.29	TLCD2	TLC domain containing 2	64	0.94
chr2_26016509_26016660	0.29	ASXL2	additional sex combs like 2 (Drosophila)	13406	0.24
chr7_50728203_50728447	0.29	GRB10	growth factor receptor-bound protein 10	33698	0.21
chr9_116351580_116351731	0.29	RP11-168K11.2		644	0.74
chr19_45682453_45683430	0.29	BLOC1S3	biogenesis of lysosomal organelles complex-1, subunit 3	14	0.95
chr13_100225058_100225209	0.29	CLYBL	citrate lyase beta like	33786	0.14
chrX_46693843_46693994	0.29	RP2	retinitis pigmentosa 2 (X-linked recessive)	2457	0.34
chr8_25056770_25056921	0.29	DOCK5	dedicator of cytokinesis 5	14465	0.23
chr11_3857643_3857812	0.29	RHOG	ras homolog family member G	1370	0.26
chr3_177662383_177662611	0.29	ENSG00000199858	.	63070	0.16
chr1_226215758_226215909	0.29	SDE2	SDE2 telomere maintenance homolog (S. pombe)	28801	0.13
chr2_28671429_28671580	0.29	PLB1	phospholipase B1	8508	0.21
chr4_160100759_160100910	0.29	ENSG00000264105	.	50788	0.13
chr18_63017285_63017436	0.29	CDH7	cadherin 7, type 2	400128	0.01
chr1_111764222_111764491	0.29	CHI3L2	chitinase 3-like 2	5282	0.15
chr2_27485345_27486489	0.29	SLC30A3	solute carrier family 30 (zinc transporter), member 3	178	0.89
chr15_36890741_36891034	0.29	C15orf41	chromosome 15 open reading frame 41	3786	0.35
chr3_36937722_36937873	0.29	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	37423	0.17
chr3_143320380_143320531	0.28	SLC9A9-AS2	SLC9A9 antisense RNA 2	220275	0.02
chr14_100532787_100533367	0.28	EVL	Enah/Vasp-like	303	0.88
chr1_68101577_68101728	0.28	ENSG00000242482	.	21160	0.21
chr6_99380585_99380736	0.28	FBXL4	F-box and leucine-rich repeat protein 4	15142	0.28
chr5_158626194_158626345	0.28	RNF145	ring finger protein 145	8373	0.18
chr14_22387734_22387885	0.28	ENSG00000222776	.	139024	0.04
chr13_37661505_37661656	0.28	CSNK1A1L	casein kinase 1, alpha 1-like	18223	0.17
chr1_212927626_212927881	0.28	NSL1	NSL1, MIS12 kinetochore complex component	37170	0.12
chr20_54987227_54988129	0.28	CASS4	Cas scaffolding protein family member 4	361	0.82
chr12_6569300_6569451	0.28	TAPBPL	TAP binding protein-like	8125	0.09
chr11_46382695_46383612	0.28	DGKZ	diacylglycerol kinase, zeta	8	0.97
chr2_109206752_109206903	0.28	LIMS1	LIM and senescent cell antigen-like domains 1	1905	0.41
chr11_121323015_121324255	0.28	RP11-730K11.1		7	0.95
chr11_47396908_47397059	0.28	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene	2959	0.13
chr20_55062041_55062192	0.27	ENSG00000238294	.	11417	0.12
chr21_34439565_34439843	0.27	OLIG1	oligodendrocyte transcription factor 1	2746	0.24
chr2_145130153_145130394	0.27	GTDC1	glycosyltransferase-like domain containing 1	40190	0.19
chr1_111415846_111416285	0.27	CD53	CD53 molecule	289	0.91
chr4_113210634_113210785	0.27	TIFA	TRAF-interacting protein with forkhead-associated domain	3650	0.19
chr20_18552180_18552331	0.27	DTD1	D-tyrosyl-tRNA deacylase 1	16282	0.12
chr12_51716816_51717143	0.27	BIN2	bridging integrator 2	920	0.52
chr14_22999291_22999566	0.27	TRAJ15	T cell receptor alpha joining 15	848	0.46
chr1_182118142_182118293	0.27	ZNF648	zinc finger protein 648	87370	0.1
chr6_51928878_51929029	0.27	ENSG00000264206	.	2449	0.3
chr4_74107274_74107425	0.27	ANKRD17	ankyrin repeat domain 17	16690	0.18
chr3_150996280_150996431	0.27	P2RY14	purinergic receptor P2Y, G-protein coupled, 14	100	0.97
chr19_49836939_49837144	0.27	CD37	CD37 molecule	1612	0.19
chr3_45735529_45735806	0.27	SACM1L	SAC1 suppressor of actin mutations 1-like (yeast)	4716	0.2
chr16_85650538_85650704	0.27	GSE1	Gse1 coiled-coil protein	3663	0.25
chr15_52860024_52861356	0.27	ARPP19	cAMP-regulated phosphoprotein, 19kDa	339	0.87
chr10_119001591_119001742	0.27	RP11-501J20.5		232	0.87
chr5_171560548_171560699	0.27	ENSG00000266671	.	52643	0.12
chr7_142496042_142496273	0.27	PRSS3P2	protease, serine, 3 pseudogene 2	15026	0.17
chr12_8608246_8608397	0.27	CLEC6A	C-type lectin domain family 6, member A	201	0.93
chr14_74769279_74769837	0.27	ABCD4	ATP-binding cassette, sub-family D (ALD), member 4	55	0.71
chr7_55601464_55601615	0.27	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	3848	0.29
chr19_45254003_45254720	0.27	BCL3	B-cell CLL/lymphoma 3	217	0.88
chr11_122940168_122940622	0.26	HSPA8	heat shock 70kDa protein 8	6457	0.15
chr1_100000240_100000391	0.26	PALMD	palmdelphin	111184	0.07
chr9_128467361_128467512	0.26	MAPKAP1	mitogen-activated protein kinase associated protein 1	2020	0.42
chr3_169725130_169725281	0.26	SEC62-AS1	SEC62 antisense RNA 1	21702	0.12
chr5_17400004_17400276	0.26	ENSG00000201715	.	54415	0.16
chr13_74601385_74601536	0.26	KLF12	Kruppel-like factor 12	32274	0.25
chr10_116582241_116583014	0.26	FAM160B1	family with sequence similarity 160, member B1	1098	0.64
chr5_100234956_100235107	0.26	ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	3887	0.35
chr10_17688880_17689112	0.26	STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	2732	0.21
chr16_57075070_57075309	0.26	NLRC5	NLR family, CARD domain containing 5	14398	0.13
chr2_242295729_242296527	0.26	FARP2	FERM, RhoGEF and pleckstrin domain protein 2	416	0.79
chr4_2487061_2487264	0.26	RNF4	ring finger protein 4	4376	0.21
chr20_218342_218531	0.26	DEFB129	defensin, beta 129	10537	0.14
chr1_158777404_158777555	0.26	MNDA	myeloid cell nuclear differentiation antigen	23628	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.6	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.5	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1	0.2	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.1	0.3	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.2	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.4	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.3	GO:0002507	tolerance induction(GO:0002507)
0.1	0.3	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.3	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.5	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.5	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.4	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.2	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.1	GO:0052555	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308) positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.1	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.6	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.3	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.1	0.7	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.1	GO:0071221	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.1	0.2	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1	0.2	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.4	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1	0.2	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.3	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.1	0.4	GO:0032816	positive regulation of natural killer cell activation(GO:0032816)
0.1	0.4	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.2	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.3	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.4	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.5	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.2	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0052572	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.2	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.4	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.2	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0001878	response to yeast(GO:0001878)
0.0	0.2	GO:0031620	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.2	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.3	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.0	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.2	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.3	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.2	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.4	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.2	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.2	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.5	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.3	GO:0030260	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.2	GO:0015669	gas transport(GO:0015669)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.1	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0030432	peristalsis(GO:0030432)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0045346	regulation of MHC class II biosynthetic process(GO:0045346)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.2	GO:0009595	detection of biotic stimulus(GO:0009595)
0.0	0.6	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:2000193	positive regulation of fatty acid transport(GO:2000193)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.3	GO:0045730	respiratory burst(GO:0045730)
0.0	1.0	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.0	GO:0045414	regulation of interleukin-8 biosynthetic process(GO:0045414)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.2	GO:0019835	cytolysis(GO:0019835)
0.0	0.1	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.1	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.2	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.1	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0060558	regulation of vitamin metabolic process(GO:0030656) vitamin D biosynthetic process(GO:0042368) regulation of vitamin D biosynthetic process(GO:0060556) regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.4	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0	0.0	GO:0006837	serotonin transport(GO:0006837)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0000303	response to superoxide(GO:0000303)
0.0	0.0	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0032892	positive regulation of organic acid transport(GO:0032892)
0.0	0.0	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0009650	UV protection(GO:0009650)
0.0	0.0	GO:0032372	negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.0	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.1	GO:2001235	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.0	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.0	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.0	GO:0048305	immunoglobulin secretion(GO:0048305) regulation of immunoglobulin secretion(GO:0051023)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.0	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0045069	regulation of viral genome replication(GO:0045069)
0.0	0.1	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
0.0	0.1	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.1	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.2	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.0	0.2	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.0	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.1	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0043584	nose development(GO:0043584)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0001554	luteolysis(GO:0001554)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.0	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.0	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.3	GO:0009060	aerobic respiration(GO:0009060)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0045606	positive regulation of epidermal cell differentiation(GO:0045606)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	0.2	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.2	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.7	GO:0001772	immunological synapse(GO:0001772)
0.1	0.2	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	0.2	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	1.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.4	GO:0005657	replication fork(GO:0005657)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.0	GO:0031904	endosome lumen(GO:0031904)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.0	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.3	GO:0005776	autophagosome(GO:0005776)
0.0	0.0	GO:0044215	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0031672	A band(GO:0031672)
0.0	0.0	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	1.1	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.3	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.0	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.8	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.4	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.3	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.3	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.3	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.4	GO:0001846	opsonin binding(GO:0001846)
0.1	0.7	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1	0.6	GO:0005522	profilin binding(GO:0005522)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	1.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.3	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.3	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.3	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.6	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.4	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.4	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.2	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.4	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.8	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.0	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	1.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0035586	purinergic receptor activity(GO:0035586)
0.0	0.6	GO:0019208	phosphatase regulator activity(GO:0019208)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.0	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.4	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.3	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.1	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	3.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.8	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.9	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.1	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.6	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.0	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.3	PID IL4 2PATHWAY	IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.1	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	1.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	1.2	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.0	REACTOME TRIF MEDIATED TLR3 SIGNALING	Genes involved in TRIF mediated TLR3 signaling
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse

Results for TBX3

Z-value: 1.99

Motif logo

Transcription factors associated with TBX3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TBX3 motif across conditions

Conditions sorted by the z-value of the TBX3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: