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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TBX4

Z-value: 0.11

Motif logo

Transcription factors associated with TBX4

Gene Symbol	Gene ID	Gene Info
TBX4 Ensembl NCBI GeneCards UniProt	ENSG00000121075.5	TBX4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
TBX4	chr17_59530124_59530284	425	0.798140	0.39	2.9e-01	Click!
TBX4	chr17_59532021_59532172	1711	0.303618	-0.33	3.8e-01	Click!
TBX4	chr17_59531737_59531888	1995	0.268096	0.27	4.9e-01	Click!
TBX4	chr17_59529188_59529339	502	0.747117	-0.19	6.3e-01	Click!
TBX4	chr17_59529820_59529988	125	0.953028	-0.09	8.2e-01	Click!

Activity of the TBX4 motif across conditions

Conditions sorted by the z-value of the TBX4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_158743544_158743695	0.02	ENSG00000231419	.	57493	0.14
chr4_75718841_75720131	0.02	BTC	betacellulin	410	0.91
chr6_105388737_105389249	0.02	LIN28B	lin-28 homolog B (C. elegans)	15930	0.23
chr2_243030793_243031816	0.02	AC093642.5		460	0.62
chr22_36235496_36235773	0.02	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	631	0.82
chr1_223302857_223303051	0.02	TLR5	toll-like receptor 5	5144	0.33
chr15_81074624_81074775	0.02	KIAA1199	KIAA1199	2987	0.3
chr8_93074610_93074813	0.02	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	480	0.89
chr7_100424107_100424380	0.02	EPHB4	EPH receptor B4	494	0.66
chr19_58769898_58770049	0.02	CTD-3138B18.6		8028	0.1
chr1_110693132_110693795	0.02	SLC6A17	solute carrier family 6 (neutral amino acid transporter), member 17	355	0.81
chr19_48102050_48102279	0.02	GLTSCR1	glioma tumor suppressor candidate region gene 1	9289	0.14
chr4_169553568_169553728	0.02	PALLD	palladin, cytoskeletal associated protein	880	0.63
chr10_15336245_15336418	0.02	RP11-25G10.2		56840	0.14
chr6_11279481_11279645	0.02	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	46648	0.16
chr5_36744281_36744616	0.02	CTD-2353F22.1		19151	0.27
chr22_46482810_46483184	0.02	FLJ27365	hsa-mir-4763	1114	0.31
chr1_205648469_205649627	0.02	SLC45A3	solute carrier family 45, member 3	539	0.74
chr16_3740619_3740949	0.02	TRAP1	TNF receptor-associated protein 1	350	0.86
chr3_87033354_87033505	0.02	VGLL3	vestigial like 3 (Drosophila)	6423	0.34
chr9_127143624_127143775	0.02	ENSG00000264237	.	30889	0.15
chr2_74606600_74607395	0.01	DCTN1	dynactin 1	413	0.73
chr11_9511154_9511374	0.01	ZNF143	zinc finger protein 143	22780	0.14
chr11_118851261_118851557	0.01	FOXR1	forkhead box R1	1920	0.13
chr8_131032307_131032560	0.01	FAM49B	family with sequence similarity 49, member B	3058	0.23
chr15_75943747_75944181	0.01	SNX33	sorting nexin 33	1867	0.18
chr19_676845_677141	0.01	FSTL3	follistatin-like 3 (secreted glycoprotein)	601	0.56
chr12_111843881_111845308	0.01	SH2B3	SH2B adaptor protein 3	842	0.62
chr11_61448104_61448359	0.01	DAGLA	diacylglycerol lipase, alpha	326	0.89
chr7_100773540_100774051	0.01	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	3416	0.13
chr13_40175117_40175459	0.01	LHFP	lipoma HMGIC fusion partner	2020	0.37
chr8_119068765_119068981	0.01	EXT1	exostosin glycosyltransferase 1	53780	0.18
chr6_28058943_28059326	0.01	ZSCAN12P1	zinc finger and SCAN domain containing 12 pseudogene 1	1071	0.38
chr19_47735595_47736220	0.01	BBC3	BCL2 binding component 3	116	0.95
chr21_17489674_17489828	0.01	ENSG00000252273	.	81922	0.11
chr10_104465015_104465218	0.01	ARL3	ADP-ribosylation factor-like 3	9048	0.15
chr15_48013744_48013895	0.01	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	3133	0.37
chr2_16832297_16832583	0.01	FAM49A	family with sequence similarity 49, member A	14656	0.3
chr7_20391312_20391720	0.01	CTA-293F17.1		20146	0.18
chr9_109624062_109624226	0.01	ZNF462	zinc finger protein 462	1234	0.53
chr14_105452072_105453062	0.01	C14orf79	chromosome 14 open reading frame 79	437	0.8
chr17_38500769_38502147	0.01	RARA	retinoic acid receptor, alpha	35	0.95
chr10_111834916_111835067	0.01	ADD3	adducin 3 (gamma)	67269	0.1
chr4_74847354_74847841	0.01	PF4	platelet factor 4	244	0.89
chr7_147097205_147097356	0.01	ENSG00000221442	.	22067	0.28
chr16_72961288_72961637	0.01	ENSG00000221799	.	57294	0.12
chr1_206687074_206687508	0.01	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	6412	0.15
chr3_190415622_190416004	0.01	ENSG00000223117	.	55861	0.15
chr4_41001068_41001219	0.01	ENSG00000201736	.	8972	0.21
chr2_239869839_239870212	0.01	ENSG00000211566	.	24681	0.17
chr2_216288358_216288696	0.01	FN1	fibronectin 1	12263	0.21
chr18_53006641_53006980	0.01	TCF4	transcription factor 4	12418	0.28
chr10_126745527_126745695	0.01	ENSG00000264572	.	24172	0.19
chr11_72975754_72976333	0.01	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	232	0.91
chr3_151046365_151046540	0.01	P2RY13	purinergic receptor P2Y, G-protein coupled, 13	884	0.57
chr19_12016806_12016962	0.01	ZNF69	zinc finger protein 69	18214	0.1
chrX_53145254_53145405	0.01	ENSG00000251707	.	14334	0.16
chr6_137242277_137243470	0.01	SLC35D3	solute carrier family 35, member D3	529	0.78
chr1_114522595_114522893	0.01	OLFML3	olfactomedin-like 3	49	0.97
chr1_235097453_235097604	0.01	ENSG00000239690	.	57595	0.14
chr5_88171366_88171720	0.01	MEF2C	myocyte enhancer factor 2C	2251	0.36
chr9_99429026_99429186	0.01	AAED1	AhpC/TSA antioxidant enzyme domain containing 1	11521	0.24
chr12_6873296_6873504	0.01	PTMS	parathymosin	2141	0.13
chr1_15527398_15527585	0.01	C1orf195	chromosome 1 open reading frame 195	29678	0.16
chr19_37129764_37129915	0.01	ZNF461	zinc finger protein 461	27886	0.11
chr5_150022452_150022802	0.01	SYNPO	synaptopodin	2387	0.23
chr21_35892920_35893071	0.01	RCAN1	regulator of calcineurin 1	3592	0.23
chr1_109045091_109045361	0.01	NBPF6	neuroblastoma breakpoint family, member 6	52283	0.14
chr13_106828289_106828440	0.01	ENSG00000222682	.	20525	0.25
chr11_74561071_74561376	0.01	ENSG00000242999	.	4268	0.2
chr14_31343280_31344466	0.01	COCH	cochlin	78	0.97
chr18_26205812_26205963	0.01	ENSG00000251719	.	422697	0.01
chr3_157248805_157248956	0.01	VEPH1	ventricular zone expressed PH domain-containing 1	2515	0.34
chr15_40697977_40698740	0.01	IVD	isovaleryl-CoA dehydrogenase	83	0.94
chr13_113597266_113598290	0.01	MCF2L	MCF.2 cell line derived transforming sequence-like	24979	0.15
chr8_126322078_126322527	0.01	ENSG00000242170	.	39456	0.16
chr18_55448645_55448916	0.01	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1	21547	0.18
chr8_8182381_8182560	0.01	SGK223	Tyrosine-protein kinase SgK223	56787	0.12
chr4_186456818_186456988	0.01	PDLIM3	PDZ and LIM domain 3	137	0.96
chr22_43005089_43005553	0.01	POLDIP3	polymerase (DNA-directed), delta interacting protein 3	5542	0.12
chr11_27743435_27743805	0.01	BDNF	brain-derived neurotrophic factor	15	0.99
chr10_10834416_10834694	0.01	CELF2	CUGBP, Elav-like family member 2	212704	0.02
chr8_96127862_96128066	0.01	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	18068	0.16
chr10_129704991_129705210	0.01	PTPRE	protein tyrosine phosphatase, receptor type, E	225	0.94
chr3_162003818_162003969	0.01	OTOL1	otolin 1	789297	0.0
chr21_37305025_37305176	0.01	FKSG68		34373	0.16
chr16_5006063_5006260	0.01	SEC14L5	SEC14-like 5 (S. cerevisiae)	2157	0.23
chr15_62737317_62737509	0.01	TLN2	talin 2	116151	0.06
chr1_21669455_21669746	0.01	ECE1	endothelin converting enzyme 1	2397	0.33
chr22_43685292_43685751	0.01	Z99756.1		13560	0.18
chr19_14605464_14605615	0.01	GIPC1	GIPC PDZ domain containing family, member 1	1405	0.26
chr7_28387506_28387665	0.01	CREB5	cAMP responsive element binding protein 5	48645	0.18
chr10_13745153_13745512	0.01	ENSG00000222235	.	1646	0.27
chr2_112456971_112457256	0.01	ENSG00000266063	.	71598	0.12
chr9_21677527_21678485	0.01	ENSG00000244230	.	21307	0.21
chr3_157157796_157157947	0.01	PTX3	pentraxin 3, long	3293	0.33
chrX_67867131_67867291	0.01	STARD8	StAR-related lipid transfer (START) domain containing 8	300	0.94
chr9_127999236_127999759	0.01	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4112	0.17
chr3_8561489_8561767	0.01	LMCD1	LIM and cysteine-rich domains 1	17241	0.2
chr15_86095041_86095192	0.01	AKAP13	A kinase (PRKA) anchor protein 13	3561	0.24
chr19_3397384_3397535	0.01	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	30875	0.13
chr19_16179581_16179939	0.01	TPM4	tropomyosin 4	1250	0.44
chr15_52860024_52861356	0.01	ARPP19	cAMP-regulated phosphoprotein, 19kDa	339	0.87
chr20_42667406_42667585	0.01	TOX2	TOX high mobility group box family member 2	15496	0.21
chr2_237570334_237570575	0.01	ACKR3	atypical chemokine receptor 3	92170	0.09
chr16_29836314_29836619	0.01	MVP	major vault protein	3820	0.08
chr11_6340007_6340271	0.01	PRKCDBP	protein kinase C, delta binding protein	1623	0.33
chr2_177361445_177361596	0.01	ENSG00000221304	.	113216	0.06
chr6_36592551_36592702	0.01	ENSG00000263894	.	2337	0.22
chr7_15503276_15503427	0.01	AGMO	alkylglycerol monooxygenase	97504	0.09
chr11_74560843_74561007	0.01	ENSG00000242999	.	3970	0.2
chr1_6803789_6803981	0.01	ENSG00000239166	.	8894	0.17
chr7_120954228_120954379	0.01	WNT16	wingless-type MMTV integration site family, member 16	11118	0.27
chr9_77725905_77726056	0.01	OSTF1	osteoclast stimulating factor 1	22521	0.16
chr17_80970427_80970618	0.01	RP11-1197K16.2		31564	0.16
chr17_2143243_2143467	0.01	SMG6	SMG6 nonsense mediated mRNA decay factor	130	0.93
chr5_176798199_176798886	0.01	RGS14	regulator of G-protein signaling 14	4598	0.11
chr10_60515616_60516529	0.01	BICC1	bicaudal C homolog 1 (Drosophila)	37223	0.22
chr19_12016356_12016507	0.01	ZNF69	zinc finger protein 69	17761	0.1
chrX_19701431_19701593	0.01	SH3KBP1	SH3-domain kinase binding protein 1	12396	0.3
chr2_43360552_43360703	0.01	ENSG00000207087	.	41995	0.18
chr1_174081654_174081874	0.01	RABGAP1L	RAB GTPase activating protein 1-like	46784	0.14
chr3_43795580_43795774	0.01	ABHD5	abhydrolase domain containing 5	42478	0.18
chr1_25870143_25871217	0.01	LDLRAP1	low density lipoprotein receptor adaptor protein 1	609	0.77
chr8_30601100_30602146	0.01	GSR	glutathione reductase	16180	0.2
chr16_75654262_75654413	0.01	ADAT1	adenosine deaminase, tRNA-specific 1	2344	0.22
chr3_43298080_43298231	0.01	SNRK	SNF related kinase	29849	0.16
chr3_149266255_149266548	0.01	ENSG00000252581	.	22983	0.17
chr3_197036778_197036943	0.01	DLG1	discs, large homolog 1 (Drosophila)	10689	0.16
chr4_113220908_113221059	0.01	ALPK1	alpha-kinase 1	2447	0.25
chr4_160096780_160097268	0.01	ENSG00000264105	.	46978	0.13
chr2_106010267_106010729	0.01	FHL2	four and a half LIM domains 2	2744	0.27
chr12_118491012_118491163	0.01	WSB2	WD repeat and SOCS box containing 2	678	0.71
chr19_53668202_53668353	0.01	CTD-2245F17.2		2596	0.18
chr10_128352295_128352662	0.01	C10orf90	chromosome 10 open reading frame 90	6537	0.3
chr1_15297301_15297452	0.01	KAZN	kazrin, periplakin interacting protein	24961	0.26
chr5_76475983_76476746	0.01	PDE8B	phosphodiesterase 8B	29910	0.15
chr7_106263871_106264022	0.01	CTB-111H14.1		16408	0.24
chr12_124773798_124773955	0.01	FAM101A	family with sequence similarity 101, member A	166	0.97
chr4_169984004_169984155	0.01	RP11-483A20.3		52498	0.12
chr3_189206116_189206267	0.01	TP63	tumor protein p63	143025	0.05
chr10_28537339_28537590	0.01	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	9798	0.27
chr11_70246165_70246316	0.01	CTTN	cortactin	1593	0.25
chr6_121760674_121760877	0.01	GJA1	gap junction protein, alpha 1, 43kDa	3937	0.22
chr18_60920514_60920680	0.01	ENSG00000238988	.	58699	0.1
chr9_6970541_6970692	0.01	KDM4C	lysine (K)-specific demethylase 4C	43172	0.19
chr17_70636816_70636967	0.01	ENSG00000200783	.	23400	0.24
chr16_87250830_87251124	0.01	RP11-899L11.3		1456	0.45
chr20_30149403_30149560	0.01	HM13-IT1	HM13 intronic transcript 1 (non-protein coding)	1488	0.28
chr20_49154846_49154997	0.01	ENSG00000239742	.	19614	0.13
chr15_68575595_68575746	0.01	FEM1B	fem-1 homolog b (C. elegans)	3373	0.24
chr15_60719892_60720043	0.01	ANXA2	annexin A2	24885	0.19
chrX_19687578_19687729	0.01	SH3KBP1	SH3-domain kinase binding protein 1	827	0.76
chr5_14268280_14268580	0.01	TRIO	trio Rho guanine nucleotide exchange factor	22656	0.28
chr18_74779349_74779519	0.01	MBP	myelin basic protein	37783	0.2
chr1_119521934_119522435	0.01	TBX15	T-box 15	8244	0.28
chr1_12579130_12579281	0.01	ENSG00000239149	.	11905	0.19
chr18_70514172_70514326	0.01	ENSG00000263750	.	6368	0.24
chr4_15907365_15907907	0.01	FGFBP1	fibroblast growth factor binding protein 1	32335	0.17
chr11_121971856_121972438	0.01	RP11-166D19.1		247	0.88
chr3_99964720_99964871	0.01	TBC1D23	TBC1 domain family, member 23	15049	0.17
chr9_115629928_115630101	0.01	RP11-408O19.5		17424	0.18
chr6_112545177_112545328	0.01	RP11-506B6.6		12042	0.18
chr8_23201528_23201679	0.01	ENSG00000253837	.	7882	0.17
chr16_66555077_66555228	0.01	TK2	thymidine kinase 2, mitochondrial	7466	0.11
chr14_69481156_69481307	0.01	ACTN1-AS1	ACTN1 antisense RNA 1	34473	0.17
chr12_40635540_40635691	0.01	LRRK2	leucine-rich repeat kinase 2	16739	0.22
chr3_149297214_149297365	0.01	WWTR1	WW domain containing transcription regulator 1	3250	0.27
chr6_144461046_144461197	0.01	STX11	syntaxin 11	10542	0.24
chr8_68304896_68305241	0.01	ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	49156	0.18
chr13_80615426_80615577	0.01	SPRY2	sprouty homolog 2 (Drosophila)	298293	0.01
chr3_177055525_177055734	0.01	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	140368	0.05
chr2_176432418_176432569	0.01	ENSG00000221347	.	237392	0.02
chr19_50009986_50010137	0.01	FCGRT	Fc fragment of IgG, receptor, transporter, alpha	5475	0.06
chrX_41243634_41243785	0.01	ENSG00000264573	.	38580	0.14
chr3_55518754_55518905	0.01	WNT5A	wingless-type MMTV integration site family, member 5A	2502	0.32
chr16_57229031_57229182	0.01	RSPRY1	ring finger and SPRY domain containing 1	8861	0.14
chr15_89636866_89637017	0.01	ABHD2	abhydrolase domain containing 2	5280	0.19
chr10_81933461_81933612	0.01	ANXA11	annexin A11	759	0.68
chr1_98685801_98685961	0.01	ENSG00000221777	.	153060	0.04
chr3_43020505_43020694	0.01	FAM198A	family with sequence similarity 198, member A	174	0.95
chr6_75992353_75992507	0.01	TMEM30A	transmembrane protein 30A	1597	0.4
chr7_19155354_19155672	0.01	TWIST1	twist family bHLH transcription factor 1	1782	0.28
chr10_14799506_14799657	0.01	FAM107B	family with sequence similarity 107, member B	17315	0.21
chr21_27762391_27762594	0.01	AP001596.6		37	0.98
chr9_88401280_88401431	0.01	AGTPBP1	ATP/GTP binding protein 1	44411	0.21
chr16_69139287_69139438	0.01	HAS3	hyaluronan synthase 3	105	0.96
chr1_224076105_224076307	0.01	TP53BP2	tumor protein p53 binding protein, 2	42532	0.17
chr1_110407367_110407518	0.01	RP11-195M16.1		21444	0.16
chr5_167004315_167004466	0.01	CTB-78F1.1		83096	0.1
chr9_108007124_108008196	0.01	SLC44A1	solute carrier family 44 (choline transporter), member 1	757	0.78
chr8_13265944_13266113	0.01	RP11-10C8.2		69945	0.11
chr22_31039873_31040024	0.01	SLC35E4	solute carrier family 35, member E4	7438	0.13
chr19_16555208_16555359	0.01	CTD-2013N17.4		3526	0.16
chr5_60745627_60745803	0.01	ENSG00000223200	.	107395	0.07
chr19_46046997_46047180	0.01	VASP	vasodilator-stimulated phosphoprotein	36339	0.08
chr4_8421351_8421502	0.01	ACOX3	acyl-CoA oxidase 3, pristanoyl	8762	0.17
chr1_38022972_38023123	0.01	DNALI1	dynein, axonemal, light intermediate chain 1	440	0.76
chr7_3957020_3957171	0.01	SDK1	sidekick cell adhesion molecule 1	33457	0.25
chr19_44179251_44179402	0.01	PLAUR	plasminogen activator, urokinase receptor	4627	0.11