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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TBX5

Z-value: 0.92

Motif logo

Transcription factors associated with TBX5

Gene Symbol	Gene ID	Gene Info
TBX5 Ensembl NCBI GeneCards UniProt	ENSG00000089225.15	TBX5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
TBX5	chr12_114744833_114744984	96795	0.080510	-0.77	1.5e-02	Click!
TBX5	chr12_114757258_114757409	84370	0.095488	-0.50	1.7e-01	Click!
TBX5	chr12_114660353_114660504	181275	0.030477	-0.39	3.0e-01	Click!
TBX5	chr12_114839312_114839463	2316	0.342807	-0.30	4.3e-01	Click!
TBX5	chr12_114700866_114701017	140762	0.046593	-0.28	4.7e-01	Click!

Activity of the TBX5 motif across conditions

Conditions sorted by the z-value of the TBX5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_640288_641115	0.92	RAB40C	RAB40C, member RAS oncogene family	369	0.68
chr16_641141_641376	0.40	RAB40C	RAB40C, member RAS oncogene family	926	0.31
chr5_176728326_176728485	0.36	RAB24	RAB24, member RAS oncogene family	2302	0.17
chr1_230262959_230263110	0.30	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	60016	0.13
chr4_100738015_100738341	0.29	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	175	0.97
chr2_219031294_219031758	0.27	CXCR1	chemokine (C-X-C motif) receptor 1	192	0.92
chr1_181002597_181002748	0.25	MR1	major histocompatibility complex, class I-related	395	0.84
chr11_47398844_47399090	0.24	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene	975	0.36
chr2_10472002_10472153	0.24	HPCAL1	hippocalcin-like 1	28251	0.15
chr4_153599291_153599457	0.24	TMEM154	transmembrane protein 154	1790	0.38
chrX_128913998_128914362	0.23	SASH3	SAM and SH3 domain containing 3	220	0.94
chr19_2289358_2289509	0.23	LINGO3	leucine rich repeat and Ig domain containing 3	2590	0.13
chr22_37317841_37317992	0.23	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	260	0.88
chr8_48515171_48515322	0.23	SPIDR	scaffolding protein involved in DNA repair	56980	0.12
chr12_54693479_54693635	0.22	NFE2	nuclear factor, erythroid 2	1242	0.21
chr7_37683935_37684086	0.22	GPR141	G protein-coupled receptor 141	39390	0.17
chr22_24038685_24038889	0.22	RGL4	ral guanine nucleotide dissociation stimulator-like 4	116	0.94
chr12_122250872_122251023	0.22	SETD1B	SET domain containing 1B	8309	0.15
chr22_50050359_50050996	0.21	C22orf34	chromosome 22 open reading frame 34	401	0.87
chr19_2089521_2089711	0.21	MOB3A	MOB kinase activator 3A	559	0.63
chr18_72256195_72256346	0.21	ZNF407	zinc finger protein 407	8836	0.21
chr13_114261602_114261753	0.20	TFDP1	transcription factor Dp-1	21936	0.18
chr6_160374023_160374174	0.20	IGF2R	insulin-like growth factor 2 receptor	16033	0.2
chr2_162101279_162101855	0.20	AC009299.2		6106	0.21
chr8_23416478_23416629	0.20	AC051642.1		4098	0.19
chr1_26870560_26870711	0.20	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	1032	0.45
chr3_126248153_126248304	0.20	CHST13	carbohydrate (chondroitin 4) sulfotransferase 13	5102	0.16
chr15_41195656_41195807	0.20	VPS18	vacuolar protein sorting 18 homolog (S. cerevisiae)	9066	0.11
chr14_69413231_69413479	0.19	ACTN1	actinin, alpha 1	910	0.65
chr3_71773124_71773375	0.19	EIF4E3	eukaryotic translation initiation factor 4E family member 3	1277	0.5
chr14_61790070_61790226	0.19	ENSG00000247287	.	612	0.51
chr10_125852855_125853389	0.19	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	84	0.98
chr7_45017874_45018185	0.19	MYO1G	myosin IG	668	0.61
chr17_29816015_29816298	0.19	RAB11FIP4	RAB11 family interacting protein 4 (class II)	1030	0.45
chr9_134903947_134904098	0.19	MED27	mediator complex subunit 27	51231	0.16
chr20_46294380_46294531	0.19	SULF2	sulfatase 2	452	0.85
chr3_184053343_184053608	0.19	FAM131A	family with sequence similarity 131, member A	239	0.85
chr10_82378763_82378914	0.19	SH2D4B	SH2 domain containing 4B	78263	0.1
chr12_53772533_53773270	0.19	SP1	Sp1 transcription factor	1059	0.4
chr17_3814974_3815160	0.19	P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1	4727	0.18
chr11_46378846_46378997	0.19	DGKZ	diacylglycerol kinase, zeta	4224	0.16
chr3_14472654_14472930	0.18	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	1386	0.5
chr8_56795950_56796101	0.18	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	3631	0.18
chr1_244488017_244488168	0.18	C1orf100	chromosome 1 open reading frame 100	27845	0.22
chr17_43302327_43302665	0.18	CTD-2020K17.1		2907	0.13
chr1_174934321_174935265	0.18	RABGAP1L	RAB GTPase activating protein 1-like	888	0.52
chr8_134086172_134086360	0.18	SLA	Src-like-adaptor	13663	0.23
chr9_129090297_129090448	0.18	MVB12B	multivesicular body subunit 12B	1244	0.58
chr13_111317307_111317458	0.18	CARS2	cysteinyl-tRNA synthetase 2, mitochondrial (putative)	11989	0.21
chr2_263631_263782	0.18	SH3YL1	SH3 and SYLF domain containing 1	326	0.81
chr10_111897137_111897288	0.18	MXI1	MAX interactor 1, dimerization protein	70151	0.1
chr1_28452985_28453161	0.18	ENSG00000253005	.	16279	0.12
chr6_38019767_38019918	0.18	ZFAND3	zinc finger, AN1-type domain 3	122107	0.06
chr1_154977279_154977430	0.18	ZBTB7B	zinc finger and BTB domain containing 7B	2059	0.13
chr5_80655477_80655628	0.18	ACOT12	acyl-CoA thioesterase 12	34410	0.17
chr8_145870561_145870712	0.17	ARHGAP39	Rho GTPase activating protein 39	39435	0.09
chr20_5100852_5101135	0.17	PCNA	proliferating cell nuclear antigen	321	0.77
chr14_71807680_71807831	0.17	RP1-261D10.2		19224	0.19
chr17_17524925_17525076	0.17	PEMT	phosphatidylethanolamine N-methyltransferase	29978	0.13
chr1_45284842_45285269	0.17	ENSG00000202444	.	614	0.49
chr12_50350018_50350169	0.17	RP11-469H8.8		185	0.9
chr19_18682141_18682437	0.17	UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1	251	0.8
chr7_8010063_8010681	0.17	AC006042.7		838	0.45
chr4_40202563_40202865	0.17	RHOH	ras homolog family member H	750	0.7
chr1_113589029_113589180	0.17	LRIG2	leucine-rich repeats and immunoglobulin-like domains 2	26727	0.22
chr9_101881133_101881552	0.17	TGFBR1	transforming growth factor, beta receptor 1	8715	0.21
chr5_180231596_180231747	0.17	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	748	0.63
chr12_123372500_123372784	0.17	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)	2064	0.29
chr1_205290973_205291124	0.17	NUAK2	NUAK family, SNF1-like kinase, 2	165	0.95
chr2_113593759_113594336	0.16	IL1B	interleukin 1, beta	36	0.97
chr1_161595583_161595734	0.16	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	5164	0.13
chr10_134823331_134823482	0.16	GPR123	G protein-coupled receptor 123	61027	0.11
chr6_35271134_35271290	0.16	DEF6	differentially expressed in FDCP 6 homolog (mouse)	5583	0.2
chr10_121351719_121352411	0.16	TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	3942	0.27
chr22_19675804_19675955	0.16	SEPT5	septin 5	26108	0.16
chr7_101929391_101929542	0.16	SH2B2	SH2B adaptor protein 2	1014	0.42
chr9_74398132_74398283	0.16	TMEM2	transmembrane protein 2	14407	0.27
chr12_51782252_51782403	0.16	GALNT6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)	2756	0.2
chr11_61739742_61739933	0.16	AP003733.1	Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801	4384	0.15
chr4_153595488_153595639	0.16	TMEM154	transmembrane protein 154	5601	0.22
chr13_110441346_110441497	0.16	IRS2	insulin receptor substrate 2	2506	0.39
chr20_56195172_56195527	0.16	ZBP1	Z-DNA binding protein 1	101	0.98
chrX_67900625_67900776	0.16	STARD8	StAR-related lipid transfer (START) domain containing 8	12793	0.29
chr17_73959756_73959907	0.16	ACOX1	acyl-CoA oxidase 1, palmitoyl	14218	0.09
chr2_238583229_238583380	0.16	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	17484	0.2
chr8_82022969_82023806	0.16	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	916	0.72
chr19_42130849_42131075	0.16	CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	2480	0.23
chr12_109084399_109085395	0.16	CORO1C	coronin, actin binding protein, 1C	5281	0.17
chr21_44466329_44466480	0.16	CBS	cystathionine-beta-synthase	12647	0.18
chr1_160616915_160617313	0.16	SLAMF1	signaling lymphocytic activation molecule family member 1	29	0.97
chr3_19188647_19189167	0.16	KCNH8	potassium voltage-gated channel, subfamily H (eag-related), member 8	1039	0.7
chr10_133608786_133608937	0.16	AL450307.1	Uncharacterized protein; cDNA FLJ46300 fis, clone TESTI4035989	13674	0.28
chr1_9689695_9689868	0.16	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	22009	0.15
chr19_33690657_33690808	0.15	LRP3	low density lipoprotein receptor-related protein 3	5242	0.14
chr19_16477276_16478284	0.15	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	5016	0.17
chr5_135348018_135348169	0.15	TGFBI	transforming growth factor, beta-induced, 68kDa	16491	0.2
chr6_27635076_27635227	0.15	ENSG00000238648	.	35963	0.14
chr1_153488579_153488730	0.15	ENSG00000263841	.	15414	0.08
chr20_61203145_61203296	0.15	ENSG00000207764	.	41101	0.09
chr20_30154465_30154616	0.15	HM13-IT1	HM13 intronic transcript 1 (non-protein coding)	3571	0.15
chr1_154981837_154981988	0.15	ZBTB7B	zinc finger and BTB domain containing 7B	5012	0.08
chr12_105076123_105076407	0.15	ENSG00000264295	.	90854	0.08
chr11_47382738_47382889	0.15	MYBPC3	myosin binding protein C, cardiac	8560	0.1
chr10_70090873_70091608	0.15	HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	592	0.65
chr2_68592484_68592752	0.15	AC015969.3		98	0.77
chr9_95728150_95728303	0.15	FGD3	FYVE, RhoGEF and PH domain containing 3	1983	0.37
chr19_3135427_3135578	0.15	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	689	0.53
chr12_54763014_54763165	0.15	GPR84	G protein-coupled receptor 84	4818	0.1
chr8_67973634_67974505	0.15	COPS5	COP9 signalosome subunit 5	483	0.5
chr9_100954099_100954367	0.15	CORO2A	coronin, actin binding protein, 2A	689	0.73
chr16_19769260_19769411	0.15	CTD-2380F24.1		8031	0.18
chr5_175968739_175969051	0.15	CDHR2	cadherin-related family member 2	617	0.6
chr2_70154628_70154779	0.14	MXD1	MAX dimerization protein 1	12383	0.12
chr7_151536159_151536670	0.14	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	24488	0.14
chr21_15917916_15918619	0.14	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	395	0.89
chr16_31271694_31271922	0.14	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	493	0.67
chr19_7894555_7894821	0.14	EVI5L	ecotropic viral integration site 5-like	431	0.73
chr14_50053552_50053772	0.14	RN7SL1	RNA, 7SL, cytoplasmic 1	364	0.55
chr17_79028934_79029085	0.14	BAIAP2	BAI1-associated protein 2	1153	0.39
chr19_31472721_31472872	0.14	AC020952.1	Uncharacterized protein	167566	0.04
chr2_102973306_102973457	0.14	IL18R1	interleukin 18 receptor 1	992	0.54
chr4_146018578_146019319	0.14	ANAPC10	anaphase promoting complex subunit 10	45	0.62
chr7_32886100_32886251	0.14	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	44590	0.14
chr1_92948652_92949059	0.14	GFI1	growth factor independent 1 transcription repressor	656	0.79
chr20_43810738_43810889	0.14	PI3	peptidase inhibitor 3, skin-derived	7296	0.15
chr2_218990770_218991030	0.14	CXCR2	chemokine (C-X-C motif) receptor 2	158	0.95
chr2_162095067_162095304	0.14	TANK	TRAF family member-associated NFKB activator	7488	0.21
chr15_75163179_75163478	0.14	SCAMP2	secretory carrier membrane protein 2	2053	0.19
chr3_193560039_193560282	0.14	ENSG00000243991	.	101650	0.07
chr1_6054566_6054852	0.14	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	1938	0.28
chr9_132949942_132950122	0.14	NCS1	neuronal calcium sensor 1	12840	0.21
chr1_182237824_182238059	0.14	ENSG00000206764	.	58262	0.14
chr1_234861269_234861851	0.14	ENSG00000201638	.	112160	0.06
chr11_111749891_111750174	0.14	C11orf1	chromosome 11 open reading frame 1	84	0.55
chr1_28502388_28502717	0.14	PTAFR	platelet-activating factor receptor	1147	0.35
chr19_54714818_54714969	0.14	RPS9	ribosomal protein S9	9865	0.07
chr22_47338919_47339070	0.14	ENSG00000221672	.	95191	0.08
chr19_42052916_42053110	0.14	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	2873	0.23
chr14_70161983_70162134	0.14	SRSF5	serine/arginine-rich splicing factor 5	31559	0.19
chr20_57225438_57225697	0.14	STX16	syntaxin 16	761	0.62
chr1_161949318_161949469	0.14	OLFML2B	olfactomedin-like 2B	5629	0.27
chr6_149639720_149640661	0.14	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	754	0.68
chr17_19015403_19015696	0.13	ENSG00000262202	.	400	0.71
chr6_26128396_26128716	0.13	HIST1H2AC	histone cluster 1, H2ac	4125	0.08
chr2_166131422_166131573	0.13	SCN2A	sodium channel, voltage-gated, type II, alpha subunit	19044	0.25
chr16_11678677_11678828	0.13	LITAF	lipopolysaccharide-induced TNF factor	1477	0.42
chr19_38826748_38826943	0.13	CATSPERG	catsper channel auxiliary subunit gamma	62	0.93
chr8_21964305_21964456	0.13	NUDT18	nudix (nucleoside diphosphate linked moiety X)-type motif 18	2530	0.17
chr8_142105442_142105593	0.13	DENND3	DENN/MADD domain containing 3	21860	0.19
chr7_156797320_156797521	0.13	MNX1-AS2	MNX1 antisense RNA 2	1581	0.33
chr12_53764513_53765147	0.13	SP1	Sp1 transcription factor	9130	0.12
chr19_41196777_41197167	0.13	NUMBL	numb homolog (Drosophila)-like	95	0.95
chr16_30078571_30078900	0.13	ALDOA	aldolase A, fructose-bisphosphate	89	0.92
chr11_119597594_119597745	0.13	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	1594	0.37
chr14_65512386_65512664	0.13	ENSG00000266531	.	1119	0.42
chr15_40599321_40599893	0.13	PLCB2	phospholipase C, beta 2	419	0.68
chr22_18250195_18250346	0.13	ENSG00000264757	.	3245	0.23
chr11_65342200_65342895	0.13	EHBP1L1	EH domain binding protein 1-like 1	962	0.29
chr9_6703919_6704260	0.13	KDM4C	lysine (K)-specific demethylase 4C	16774	0.21
chr19_41856873_41857286	0.13	TMEM91	transmembrane protein 91	263	0.82
chr17_43306981_43307138	0.13	CTD-2020K17.1		7470	0.1
chr8_97864758_97864909	0.13	CPQ	carboxypeptidase Q	91365	0.1
chr15_65136767_65137537	0.13	AC069368.3	Uncharacterized protein	3005	0.17
chr3_11118976_11119127	0.13	SLC6A1-AS1	SLC6A1 antisense RNA 1	58141	0.12
chr10_14611757_14612021	0.13	FAM107B	family with sequence similarity 107, member B	2140	0.39
chr11_67186046_67186291	0.13	PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	2484	0.1
chr20_62670859_62671010	0.13	ZNF512B	zinc finger protein 512B	996	0.34
chr4_81000146_81000297	0.13	ANTXR2	anthrax toxin receptor 2	5595	0.31
chr15_40571810_40571961	0.13	ANKRD63	ankyrin repeat domain 63	2902	0.13
chr3_65965301_65965465	0.13	ENSG00000202071	.	24232	0.16
chr17_39738951_39739102	0.13	KRT14	keratin 14	4147	0.12
chr2_28691966_28692117	0.13	PLB1	phospholipase B1	12029	0.22
chr15_69380999_69381150	0.13	RP11-809H16.4		45169	0.13
chr1_210473057_210473208	0.12	HHAT	hedgehog acyltransferase	28464	0.19
chr20_23067571_23067722	0.12	CD93	CD93 molecule	669	0.69
chr17_46607108_46607259	0.12	HOXB1	homeobox B1	1089	0.3
chr20_20691484_20691635	0.12	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)	1572	0.49
chr10_105599968_105600119	0.12	SH3PXD2A	SH3 and PX domains 2A	15121	0.2
chr6_157097564_157098248	0.12	ARID1B	AT rich interactive domain 1B (SWI1-like)	1157	0.47
chr8_19539783_19540152	0.12	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	127	0.98
chr19_11466484_11467017	0.12	DKFZP761J1410	Lipid phosphate phosphatase-related protein type 2	576	0.52
chr6_12010262_12011396	0.12	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	1404	0.51
chr20_10741569_10741720	0.12	JAG1	jagged 1	86950	0.09
chr19_35494097_35494396	0.12	GRAMD1A	GRAM domain containing 1A	2886	0.14
chr17_27223716_27224346	0.12	FLOT2	flotillin 2	639	0.35
chr16_3057439_3057643	0.12	LA16c-380H5.2		2439	0.09
chr12_72149024_72149971	0.12	RAB21	RAB21, member RAS oncogene family	843	0.67
chr16_85075183_85075477	0.12	KIAA0513	KIAA0513	13920	0.21
chr12_14718728_14718879	0.12	RP11-695J4.2		1881	0.26
chr8_121757630_121757781	0.12	RP11-713M15.1		15788	0.25
chr16_85815842_85815993	0.12	ENSG00000252311	.	412	0.72
chr1_149608228_149608379	0.12	ENSG00000202496	.	2386	0.21
chr10_126697072_126697223	0.12	CTBP2	C-terminal binding protein 2	2565	0.29
chr4_6912691_6912996	0.12	TBC1D14	TBC1 domain family, member 14	868	0.61
chr18_34704825_34704976	0.12	KIAA1328	KIAA1328	58071	0.15
chr3_175522251_175522402	0.12	NAALADL2-AS1	NAALADL2 antisense RNA 1	28205	0.2
chr20_43150070_43150299	0.12	SERINC3	serine incorporator 3	467	0.76
chr8_8945449_8945788	0.12	ENSG00000239078	.	15592	0.15
chr17_56595689_56596135	0.12	MTMR4	myotubularin related protein 4	646	0.52
chr2_46561320_46561471	0.12	EPAS1	endothelial PAS domain protein 1	36854	0.19

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.1	0.2	GO:0034113	heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.2	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.2	GO:0002467	germinal center formation(GO:0002467)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.4	GO:0035338	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.2	GO:0045350	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.2	GO:0050901	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.3	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:1903224	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0032069	regulation of nuclease activity(GO:0032069)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.2	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.0	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0006991	response to sterol depletion(GO:0006991)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.0	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.0	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.8	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.1	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.1	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0006623	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.2	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:1905145	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.0	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.0	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.2	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0060479	lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0	0.0	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.0	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.0	GO:0010713	negative regulation of collagen metabolic process(GO:0010713) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0001783	B cell apoptotic process(GO:0001783)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.0	GO:0072179	nephric duct formation(GO:0072179)
0.0	0.0	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0045911	positive regulation of DNA recombination(GO:0045911)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0052472	modulation by host of viral transcription(GO:0043921) modulation by host of symbiont transcription(GO:0052472)
0.0	0.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.0	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0045495	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.2	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.1	0.3	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.8	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.0	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.3	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.0	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.0	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.0	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.8	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.3	PID INSULIN PATHWAY	Insulin Pathway
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.5	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors