Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for TCF21

Z-value: 1.14

Motif logo

logo of

Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
TCF21
ENSG00000118526.6 transcription factor 21

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_134210706_134210991TCF213750.698482-0.314.2e-01Click!
chr6_134210535_134210686TCF211370.830676-0.294.5e-01Click!
chr6_134211072_134211606TCF218660.5024620.215.8e-01Click!
chr6_134210328_134210483TCF21680.7579230.098.1e-01Click!

Activity of the TCF21 motif across conditions

Conditions sorted by the z-value of the TCF21 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_145276293_145276624 0.58 ZEB2-AS1
 ZEB2 antisense RNA 1
 434
 0.52
chr6_159465378_159465638 0.50 TAGAP
 T-cell activation RhoGTPase activating protein
 542
 0.78
chr20_31351724_31351875 0.47 DNMT3B
 DNA (cytosine-5-)-methyltransferase 3 beta
 1351
 0.43
chr19_15580169_15580596 0.44 RASAL3
 RAS protein activator like 3
 5000
 0.14
chr12_8862062_8862268 0.38 RIMKLB
 ribosomal modification protein rimK-like family member B
 9723
 0.17
chr20_52464106_52464266 0.38 AC005220.3
92513
 0.08
chr8_8610679_8610830 0.37 CLDN23
 claudin 23
 51306
 0.15
chr12_57828470_57828621 0.37 INHBC
 inhibin, beta C
 2
 0.95
chr15_57508769_57508920 0.35 TCF12
 transcription factor 12
 2784
 0.37
chr8_125617266_125617519 0.35 RP11-532M24.1
25520
 0.16
chr7_64349557_64349866 0.35 RP11-797H7.5
767
 0.67
chr12_9142516_9142764 0.34 KLRG1
 killer cell lectin-like receptor subfamily G, member 1
 423
 0.81
chr18_22811215_22811414 0.33 ZNF521
 zinc finger protein 521
 180
 0.97
chr14_75801139_75801383 0.33 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 54365
 0.1
chr1_245215310_245215673 0.33 ENSG00000251754
 .
 8261
 0.17
chr19_16427219_16427370 0.32 CTD-2562J15.6
8031
 0.16
chr21_46970159_46970310 0.32 SLC19A1
 solute carrier family 19 (folate transporter), member 1
 5909
 0.24
chr11_1874347_1875032 0.31 LSP1
 lymphocyte-specific protein 1
 489
 0.65
chr10_54514994_54515145 0.31 RP11-556E13.1
100
 0.98
chr1_114483508_114483659 0.31 HIPK1
 homeodomain interacting protein kinase 1
 10184
 0.13
chr4_82426507_82426753 0.31 RASGEF1B
 RasGEF domain family, member 1B
 33561
 0.24
chr8_41623788_41623939 0.30 ANK1
 ankyrin 1, erythrocytic
 31277
 0.15
chr11_64512499_64513555 0.30 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
 99
 0.95
chr3_184869954_184870148 0.29 C3orf70
 chromosome 3 open reading frame 70
 751
 0.7
chr17_68166046_68166268 0.29 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 481
 0.55
chr21_44524771_44524948 0.29 U2AF1
 U2 small nuclear RNA auxiliary factor 1
 503
 0.75
chr1_109204500_109204651 0.29 HENMT1
 HEN1 methyltransferase homolog 1 (Arabidopsis)
 427
 0.83
chr17_143001_143152 0.29 RP11-1260E13.1
28107
 0.13
chr13_78493097_78493683 0.29 EDNRB
 endothelin receptor type B
 424
 0.48
chr1_245018870_245019021 0.29 HNRNPU-AS1
 HNRNPU antisense RNA 1
 146
 0.95
chr1_184121550_184121895 0.29 ENSG00000199840
 .
 19235
 0.25
chr7_50357605_50357756 0.28 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 9362
 0.29
chr1_59782411_59782670 0.28 FGGY
 FGGY carbohydrate kinase domain containing
 6781
 0.34
chr11_67778123_67778316 0.28 ALDH3B1
 aldehyde dehydrogenase 3 family, member B1
 429
 0.73
chr4_128553582_128553997 0.28 INTU
 inturned planar cell polarity protein
 298
 0.94
chr6_158622105_158622256 0.28 ENSG00000265803
 .
 26164
 0.16
chr12_117036919_117037510 0.28 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 23558
 0.24
chr5_90478735_90478954 0.28 ENSG00000199643
 .
 87700
 0.1
chr12_56138916_56139328 0.28 GDF11
 growth differentiation factor 11
 1939
 0.16
chr4_76822812_76822963 0.27 PPEF2
 protein phosphatase, EF-hand calcium binding domain 2
 794
 0.58
chr5_17144956_17145201 0.27 ENSG00000251990
 .
 12102
 0.2
chr17_40283670_40283821 0.27 RAB5C
 RAB5C, member RAS oncogene family
 2968
 0.13
chr21_34443663_34444086 0.27 AP000282.2
464
 0.55
chr15_59978021_59978291 0.27 RP11-361D15.2
2560
 0.21
chr1_154171748_154172121 0.27 TPM3
 tropomyosin 3
 4810
 0.1
chr5_50007615_50007766 0.26 PARP8
 poly (ADP-ribose) polymerase family, member 8
 44299
 0.21
chr6_31555088_31555348 0.26 LST1
 leukocyte specific transcript 1
 125
 0.86
chr2_101841003_101841154 0.26 CNOT11
 CCR4-NOT transcription complex, subunit 11
 28186
 0.16
chr21_34185899_34186080 0.26 C21orf62
 chromosome 21 open reading frame 62
 0
 0.97
chr15_48909824_48909975 0.26 FBN1
 fibrillin 1
 28019
 0.23
chr7_148330575_148330726 0.26 C7orf33
 chromosome 7 open reading frame 33
 42993
 0.14
chr3_150995962_150996155 0.26 P2RY14
 purinergic receptor P2Y, G-protein coupled, 14
 99
 0.97
chr14_91111245_91111396 0.26 TTC7B
 tetratricopeptide repeat domain 7B
 768
 0.6
chr4_153459378_153459529 0.26 ENSG00000268471
 .
 1873
 0.31
chr9_71174970_71175121 0.25 TMEM252
 transmembrane protein 252
 19262
 0.25
chr6_133068019_133068170 0.25 RP1-55C23.7
5720
 0.13
chr9_6913439_6913590 0.25 RP11-403H13.1
10844
 0.24
chr14_23288815_23289060 0.25 SLC7A7
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
 7
 0.95
chr6_136791083_136791234 0.25 MAP7
 microtubule-associated protein 7
 3145
 0.32
chr6_46376004_46376155 0.25 RCAN2
 regulator of calcineurin 2
 48634
 0.16
chr20_52703439_52703654 0.24 BCAS1
 breast carcinoma amplified sequence 1
 16242
 0.21
chr1_160681036_160681588 0.24 CD48
 CD48 molecule
 281
 0.89
chr11_32460808_32460959 0.24 WT1-AS
 WT1 antisense RNA
 967
 0.61
chr4_15418160_15418311 0.24 RP11-484O2.1
3421
 0.22
chrX_131624482_131624759 0.24 MBNL3
 muscleblind-like splicing regulator 3
 624
 0.83
chr12_14796282_14796433 0.24 RP11-174G6.1
22232
 0.16
chr2_115918703_115918854 0.24 DPP10-AS1
 DPP10 antisense RNA 1
 10
 0.88
chr12_123752691_123752842 0.24 CDK2AP1
 cyclin-dependent kinase 2 associated protein 1
 65
 0.95
chr17_61778306_61778706 0.24 LIMD2
 LIM domain containing 2
 26
 0.97
chr11_8228040_8228278 0.24 RIC3
 RIC3 acetylcholine receptor chaperone
 37557
 0.16
chr7_55601634_55601785 0.24 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 3678
 0.29
chr5_123392522_123392673 0.24 CSNK1G3
 casein kinase 1, gamma 3
 468478
 0.01
chr3_23804583_23804865 0.24 ENSG00000238672
 .
 4378
 0.25
chr1_108593520_108593821 0.24 ENSG00000264753
 .
 32277
 0.19
chr7_88025228_88025379 0.24 ENSG00000207094
 .
 53243
 0.15
chr10_92690511_92690662 0.24 ENSG00000201604
 .
 7994
 0.19
chr15_86126252_86126683 0.23 RP11-815J21.2
3058
 0.23
chr1_211500199_211501024 0.23 TRAF5
 TNF receptor-associated factor 5
 432
 0.87
chr1_234910955_234911218 0.23 ENSG00000201638
 .
 62634
 0.13
chr11_128588908_128589084 0.23 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 23078
 0.17
chr9_13787686_13787970 0.23 NFIB
 nuclear factor I/B
 392963
 0.01
chr2_127417167_127417318 0.23 GYPC
 glycophorin C (Gerbich blood group)
 3482
 0.34
chr2_168438647_168438800 0.23 ENSG00000238357
 .
 49328
 0.19
chr5_35781420_35781571 0.23 SPEF2
 sperm flagellar 2
 2225
 0.36
chr17_66596046_66596347 0.23 FAM20A
 family with sequence similarity 20, member A
 1334
 0.52
chr6_24919733_24919934 0.23 FAM65B
 family with sequence similarity 65, member B
 8638
 0.23
chr12_75875877_75876340 0.23 GLIPR1
 GLI pathogenesis-related 1
 1124
 0.49
chr2_174890200_174890425 0.23 SP3
 Sp3 transcription factor
 59882
 0.15
chr11_35144138_35144289 0.23 AL356215.1
6002
 0.19
chr15_63524002_63524153 0.23 RAB8B
 RAB8B, member RAS oncogene family
 42272
 0.14
chr5_137691113_137691264 0.23 KDM3B
 lysine (K)-specific demethylase 3B
 2903
 0.18
chr3_107821041_107821248 0.23 CD47
 CD47 molecule
 11272
 0.29
chr17_3865236_3865510 0.23 ATP2A3
 ATPase, Ca++ transporting, ubiquitous
 2212
 0.29
chr10_112357348_112357499 0.23 ENSG00000239125
 .
 21305
 0.14
chr11_123229225_123229659 0.23 ENSG00000265357
 .
 22778
 0.2
chr2_43455773_43455924 0.23 AC010883.5
864
 0.61
chr5_95066383_95066820 0.23 RHOBTB3
 Rho-related BTB domain containing 3
 25
 0.96
chr11_118110290_118110538 0.23 MPZL3
 myelin protein zero-like 3
 12648
 0.13
chr13_24210772_24210935 0.23 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 57334
 0.14
chr1_31460456_31460607 0.23 PUM1
 pumilio RNA-binding family member 1
 7375
 0.18
chr16_23161362_23161529 0.22 USP31
 ubiquitin specific peptidase 31
 854
 0.66
chr12_121677598_121677871 0.22 CAMKK2
 calcium/calmodulin-dependent protein kinase kinase 2, beta
 20611
 0.16
chr1_110159560_110159711 0.22 AMPD2
 adenosine monophosphate deaminase 2
 909
 0.36
chr1_151592946_151593154 0.22 RP11-404E16.1
7211
 0.11
chr17_38604215_38604366 0.22 IGFBP4
 insulin-like growth factor binding protein 4
 4577
 0.16
chr19_12889048_12889583 0.22 HOOK2
 hook microtubule-tethering protein 2
 44
 0.92
chr2_74804644_74804826 0.22 LOXL3
 lysyl oxidase-like 3
 21918
 0.09
chr2_60638627_60638831 0.22 ENSG00000266078
 .
 24149
 0.2
chr11_118085317_118085565 0.22 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 165
 0.94
chrX_128914480_128914899 0.22 SASH3
 SAM and SH3 domain containing 3
 729
 0.68
chr12_111618967_111619231 0.22 CUX2
 cut-like homeobox 2
 81849
 0.09
chr9_93564472_93565060 0.22 SYK
 spleen tyrosine kinase
 557
 0.87
chr3_105295301_105295452 0.22 ALCAM
 activated leukocyte cell adhesion molecule
 42930
 0.21
chr10_130832704_130832855 0.22 MGMT
 O-6-methylguanine-DNA methyltransferase
 432669
 0.01
chr1_212325647_212325798 0.22 ENSG00000252879
 .
 52704
 0.12
chr18_56245541_56245920 0.22 RP11-126O1.2
21428
 0.14
chr14_35179286_35179550 0.22 CFL2
 cofilin 2 (muscle)
 3616
 0.25
chr14_88474301_88474452 0.22 GPR65
 G protein-coupled receptor 65
 2908
 0.23
chr5_141872256_141872598 0.22 ENSG00000252831
 .
 41483
 0.18
chr8_120650260_120650433 0.22 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
 674
 0.78
chr11_122536513_122536664 0.21 UBASH3B
 ubiquitin associated and SH3 domain containing B
 10205
 0.24
chr2_238598166_238598563 0.21 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 2424
 0.34
chr6_32920569_32920784 0.21 HLA-DMA
 major histocompatibility complex, class II, DM alpha
 162
 0.56
chr2_40907638_40908036 0.21 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 69644
 0.14
chr11_42107655_42107806 0.21 LRRC4C
 leucine rich repeat containing 4C
 626407
 0.0
chr10_94515647_94515798 0.21 ENSG00000201412
 .
 45357
 0.14
chr18_66505598_66505749 0.21 CCDC102B
 coiled-coil domain containing 102B
 1672
 0.41
chr8_116675050_116675578 0.21 TRPS1
 trichorhinophalangeal syndrome I
 1409
 0.6
chr15_69695885_69696036 0.21 ENSG00000207395
 .
 2820
 0.17
chr4_87050749_87050921 0.21 RP11-778J15.1
9968
 0.23
chr8_74283083_74283286 0.21 RP11-434I12.2
14488
 0.25
chr9_139423244_139423395 0.21 ENSG00000263403
 .
 9241
 0.09
chr18_9083293_9083444 0.21 NDUFV2
 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
 19260
 0.17
chr8_117163981_117164132 0.21 ENSG00000221793
 .
 15058
 0.29
chr15_63524568_63524719 0.21 RAB8B
 RAB8B, member RAS oncogene family
 42838
 0.14
chr13_103423092_103423243 0.21 TEX30
 testis expressed 30
 17
 0.96
chr2_74264500_74264778 0.21 TET3
 tet methylcytosine dioxygenase 3
 8811
 0.18
chr11_63319075_63319226 0.21 HRASLS2
 HRAS-like suppressor 2
 11705
 0.14
chr15_63795725_63795911 0.21 USP3
 ubiquitin specific peptidase 3
 975
 0.63
chr10_26778557_26778708 0.21 ENSG00000199733
 .
 19886
 0.24
chr2_233949302_233949453 0.21 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
 24188
 0.17
chr9_83728640_83728791 0.21 ENSG00000221581
 .
 379471
 0.01
chr18_52519559_52519845 0.21 RAB27B
 RAB27B, member RAS oncogene family
 24272
 0.21
chr13_77899686_77900769 0.21 MYCBP2
 MYC binding protein 2, E3 ubiquitin protein ligase
 587
 0.85
chr18_52495652_52496658 0.21 RAB27B
 RAB27B, member RAS oncogene family
 725
 0.77
chr2_118773318_118773469 0.21 ENSG00000243510
 .
 565
 0.64
chr13_99195550_99195827 0.21 STK24
 serine/threonine kinase 24
 21436
 0.2
chr7_138293225_138293376 0.21 ENSG00000252188
 .
 16624
 0.23
chr21_46573190_46573341 0.21 ADARB1
 adenosine deaminase, RNA-specific, B1
 18292
 0.17
chr8_1904836_1904987 0.21 KBTBD11
 kelch repeat and BTB (POZ) domain containing 11
 17133
 0.24
chr4_53017131_53017386 0.21 SPATA18
 spermatogenesis associated 18
 99676
 0.08
chr3_133661654_133661805 0.21 C3orf36
 chromosome 3 open reading frame 36
 13073
 0.23
chr8_23997445_23997596 0.20 ENSG00000207201
 .
 62849
 0.14
chr17_45334525_45334676 0.20 ENSG00000238419
 .
 2186
 0.21
chr6_13273500_13273733 0.20 PHACTR1
 phosphatase and actin regulator 1
 627
 0.46
chr6_107021251_107021402 0.20 AIM1
 absent in melanoma 1
 32297
 0.14
chr19_42260620_42260771 0.20 CEACAM6
 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
 1366
 0.33
chr9_134150260_134150411 0.20 FAM78A
 family with sequence similarity 78, member A
 1599
 0.36
chr21_36612358_36612509 0.20 RUNX1
 runt-related transcription factor 1
 190792
 0.03
chr8_23366659_23366810 0.20 SLC25A37
 solute carrier family 25 (mitochondrial iron transporter), member 37
 19584
 0.16
chr3_9004693_9005124 0.20 RAD18
 RAD18 homolog (S. cerevisiae)
 278
 0.92
chr1_167619596_167619862 0.20 RP3-455J7.4
19818
 0.18
chr3_151963057_151963208 0.20 MBNL1
 muscleblind-like splicing regulator 1
 22697
 0.21
chr3_15313694_15313943 0.20 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 3598
 0.18
chr4_120291951_120292186 0.20 ENSG00000201186
 .
 3351
 0.26
chr18_9113256_9113407 0.20 RP11-143J12.3
2544
 0.24
chr8_121822100_121822251 0.20 SNTB1
 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
 2208
 0.3
chr6_110555384_110555535 0.20 CDC40
 cell division cycle 40
 53835
 0.13
chr3_18487175_18487565 0.20 SATB1
 SATB homeobox 1
 290
 0.75
chr2_233948085_233948236 0.20 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
 22971
 0.18
chr2_172877202_172877353 0.20 METAP1D
 methionyl aminopeptidase type 1D (mitochondrial)
 12787
 0.23
chr1_8761101_8761375 0.20 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 2040
 0.41
chr6_75877058_75877209 0.20 COL12A1
 collagen, type XII, alpha 1
 15228
 0.25
chr12_76413840_76414001 0.20 RP11-290L1.3
10354
 0.19
chr1_246945751_246945958 0.20 ENSG00000227953
 .
 6460
 0.17
chrX_118407364_118407689 0.20 PGRMC1
 progesterone receptor membrane component 1
 37238
 0.17
chr9_6959941_6960092 0.20 KDM4C
 lysine (K)-specific demethylase 4C
 34515
 0.21
chr7_131240036_131240570 0.20 PODXL
 podocalyxin-like
 1063
 0.65
chr8_97523748_97523899 0.20 SDC2
 syndecan 2
 17587
 0.25
chr17_48218383_48218580 0.20 AC002401.1
5530
 0.1
chr13_33752733_33752884 0.20 STARD13
 StAR-related lipid transfer (START) domain containing 13
 7408
 0.23
chr5_142381326_142381532 0.20 ARHGAP26
 Rho GTPase activating protein 26
 35332
 0.22
chr9_81972295_81972446 0.20 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 214318
 0.03
chr1_150972321_150972472 0.20 FAM63A
 family with sequence similarity 63, member A
 1750
 0.17
chr3_184893391_184893626 0.20 EHHADH-AS1
 EHHADH antisense RNA 1
 12819
 0.2
chr4_65504939_65505090 0.19 TECRL
 trans-2,3-enoyl-CoA reductase-like
 229828
 0.02
chr4_6927460_6927611 0.19 TBC1D14
 TBC1 domain family, member 14
 15560
 0.16
chr5_156540231_156540382 0.19 HAVCR2
 hepatitis A virus cellular receptor 2
 3581
 0.17
chr1_66868301_66868452 0.19 PDE4B
 phosphodiesterase 4B, cAMP-specific
 48311
 0.18
chr18_53254177_53254364 0.19 TCF4
 transcription factor 4
 77
 0.98
chr2_207938706_207938857 0.19 ENSG00000253008
 .
 36016
 0.16
chr6_112960793_112960944 0.19 ENSG00000252215
 .
 107484
 0.07
chr13_114064294_114064563 0.19 ADPRHL1
 ADP-ribosylhydrolase like 1
 39029
 0.11
chr2_101478838_101478989 0.19 AC092168.2
39790
 0.16
chr10_88170804_88170968 0.19 GRID1
 glutamate receptor, ionotropic, delta 1
 44651
 0.14
chr12_123713655_123713840 0.19 MPHOSPH9
 M-phase phosphoprotein 9
 1246
 0.35
chr20_10457057_10457208 0.19 SLX4IP
 SLX4 interacting protein
 41181
 0.16
chr18_60605343_60605494 0.19 PHLPP1
 PH domain and leucine rich repeat protein phosphatase 1
 35035
 0.2
chr1_162469519_162469670 0.19 UHMK1
 U2AF homology motif (UHM) kinase 1
 1961
 0.33
chr12_10876110_10876483 0.19 YBX3
 Y box binding protein 3
 385
 0.85

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.2 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.2 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1 0.2 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.3 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0070339 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.2 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.2 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.0 GO:0002246 wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.0 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.0 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.0 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.0 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.0 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.0 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691) negative regulation of interleukin-1 production(GO:0032692)
0.0 0.0 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:0052167 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.0 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.0 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.3 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME PLATELET HOMEOSTASIS Genes involved in Platelet homeostasis
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR