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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for TCF3_MYOG

Z-value: 0.35

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Transcription factors associated with TCF3_MYOG

Gene Symbol Gene ID Gene Info
TCF3
ENSG00000071564.10 transcription factor 3
MYOG
ENSG00000122180.4 myogenin

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_203044604_203044831MYOG104470.130208-0.491.8e-01Click!
chr1_203052021_203052172MYOG30680.179211-0.353.5e-01Click!
chr1_203044981_203045143MYOG101020.130813-0.215.9e-01Click!
chr1_203045268_203045454MYOG98030.131356-0.068.7e-01Click!
chr19_1682723_1682874TCF3301940.105053-0.627.7e-02Click!
chr19_1675853_1676228TCF3234360.114431-0.571.1e-01Click!
chr19_1653201_1653411TCF37020.5736030.422.6e-01Click!
chr19_1701461_1701612TCF3489320.076519-0.412.7e-01Click!
chr19_1650811_1650962TCF31420.935336-0.393.0e-01Click!

Activity of the TCF3_MYOG motif across conditions

Conditions sorted by the z-value of the TCF3_MYOG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_160681036_160681588 0.33 CD48
 CD48 molecule
 281
 0.89
chr22_42177525_42177912 0.25 MEI1
 meiosis inhibitor 1
 21
 0.96
chr22_21738155_21738638 0.22 RIMBP3B
 RIMS binding protein 3B
 733
 0.51
chr22_20460794_20461266 0.21 RIMBP3
 RIMS binding protein 3
 756
 0.52
chr11_84028149_84028546 0.20 DLG2
 discs, large homolog 2 (Drosophila)
 35
 0.99
chr12_133006842_133006993 0.20 MUC8
 mucin 8
 43809
 0.14
chrX_13103844_13104411 0.20 FAM9C
 family with sequence similarity 9, member C
 41326
 0.19
chr2_240188602_240189192 0.19 ENSG00000265215
 .
 38260
 0.14
chr22_21904755_21905186 0.19 RIMBP3C
 RIMS binding protein 3C
 150
 0.88
chr15_60419498_60420019 0.18 FOXB1
 forkhead box B1
 123337
 0.06
chr2_25562492_25562759 0.18 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 2129
 0.34
chr5_169729652_169729829 0.18 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 4509
 0.25
chr5_150535420_150535844 0.18 ANXA6
 annexin A6
 1676
 0.39
chr19_3180678_3181240 0.17 S1PR4
 sphingosine-1-phosphate receptor 4
 2223
 0.2
chr11_118212224_118212431 0.17 CD3D
 CD3d molecule, delta (CD3-TCR complex)
 675
 0.54
chr1_65530319_65530470 0.17 ENSG00000199135
 .
 6203
 0.2
chr11_65407442_65407916 0.17 SIPA1
 signal-induced proliferation-associated 1
 87
 0.92
chr20_56195172_56195527 0.16 ZBP1
 Z-DNA binding protein 1
 101
 0.98
chr13_52398191_52398536 0.16 RP11-327P2.5
19930
 0.17
chr10_73531816_73531986 0.16 C10orf54
 chromosome 10 open reading frame 54
 1354
 0.44
chr10_104420612_104420763 0.16 TRIM8
 tripartite motif containing 8
 16043
 0.16
chr18_2967390_2967541 0.16 RP11-737O24.1
449
 0.78
chr3_50646848_50647098 0.16 CISH
 cytokine inducible SH2-containing protein
 2230
 0.22
chr19_48835948_48836196 0.15 EMP3
 epithelial membrane protein 3
 7207
 0.11
chr13_75900551_75900966 0.15 TBC1D4
 TBC1 domain family, member 4
 14909
 0.24
chr18_43266884_43267229 0.15 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 20949
 0.17
chr3_114832402_114832553 0.15 ZBTB20
 zinc finger and BTB domain containing 20
 33641
 0.25
chrX_44203680_44203969 0.15 EFHC2
 EF-hand domain (C-terminal) containing 2
 906
 0.71
chr20_35274684_35274835 0.15 SLA2
 Src-like-adaptor 2
 140
 0.94
chr2_220408420_220408618 0.14 CHPF
 chondroitin polymerizing factor
 10
 0.62
chr14_91840122_91840324 0.14 ENSG00000265856
 .
 40166
 0.15
chrY_15863423_15864046 0.14 KALP
 Kallmann syndrome sequence pseudogene
 198
 0.96
chr8_128988445_128988635 0.14 ENSG00000221771
 .
 15661
 0.16
chr7_150434707_150435064 0.14 GIMAP5
 GTPase, IMAP family member 5
 449
 0.8
chr6_144655565_144656031 0.14 RP1-91J24.3
1361
 0.51
chr1_244215459_244215610 0.14 ZBTB18
 zinc finger and BTB domain containing 18
 949
 0.61
chr7_72300733_72300925 0.14 SBDSP1
 Shwachman-Bodian-Diamond syndrome pseudogene 1
 594
 0.6
chr11_2323777_2324127 0.14 TSPAN32
 tetraspanin 32
 1
 0.92
chr7_150148052_150148382 0.14 GIMAP8
 GTPase, IMAP family member 8
 499
 0.78
chr17_4615541_4615774 0.14 ARRB2
 arrestin, beta 2
 1663
 0.18
chr20_50158140_50158637 0.14 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 870
 0.72
chr22_24039509_24039689 0.14 RGL4
 ral guanine nucleotide dissociation stimulator-like 4
 928
 0.45
chr6_32813075_32813316 0.13 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
 582
 0.44
chr16_27413508_27414237 0.13 IL21R
 interleukin 21 receptor
 377
 0.88
chr4_16219327_16219478 0.13 TAPT1
 transmembrane anterior posterior transformation 1
 8692
 0.2
chr14_106854492_106854843 0.13 IGHV3-37
 immunoglobulin heavy variable 3-37 (pseudogene)
 1641
 0.1
chr17_80260072_80260536 0.13 CD7
 CD7 molecule
 15124
 0.1
chr16_28996496_28996848 0.13 LAT
 linker for activation of T cells
 11
 0.94
chr15_21995486_21996039 0.13 DKFZP547L112
15608
 0.19
chr15_75082884_75083035 0.13 ENSG00000264386
 .
 1861
 0.2
chr10_129985976_129986188 0.13 MKI67
 marker of proliferation Ki-67
 61433
 0.15
chr1_209930383_209930698 0.12 TRAF3IP3
 TRAF3 interacting protein 3
 1016
 0.45
chrX_153267742_153268222 0.12 IRAK1
 interleukin-1 receptor-associated kinase 1
 11715
 0.09
chr15_29211815_29211966 0.12 APBA2
 amyloid beta (A4) precursor protein-binding, family A, member 2
 320
 0.92
chr1_225654970_225655492 0.12 RP11-496N12.6
2186
 0.34
chr22_32598633_32598888 0.12 RFPL2
 ret finger protein-like 2
 704
 0.6
chr17_43305439_43305590 0.12 CTD-2020K17.1
5925
 0.1
chr11_1874347_1875032 0.12 LSP1
 lymphocyte-specific protein 1
 489
 0.65
chr2_225803456_225803653 0.12 DOCK10
 dedicator of cytokinesis 10
 8228
 0.3
chr15_20988807_20989390 0.12 AC012414.1
 Uncharacterized protein
 15589
 0.17
chr17_8868395_8868683 0.12 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 485
 0.85
chr11_67186046_67186291 0.12 PPP1CA
 protein phosphatase 1, catalytic subunit, alpha isozyme
 2484
 0.1
chr22_22292604_22292980 0.12 LL22NC03-86G7.1
127
 0.51
chr17_38720511_38720770 0.12 CCR7
 chemokine (C-C motif) receptor 7
 1071
 0.49
chr20_62369505_62369786 0.12 RP4-583P15.14
22
 0.92
chr11_67176924_67177082 0.12 TBC1D10C
 TBC1 domain family, member 10C
 5343
 0.07
chr6_31238477_31238986 0.12 HLA-C
 major histocompatibility complex, class I, C
 1115
 0.41
chr17_4617667_4617818 0.12 ARRB2
 arrestin, beta 2
 1142
 0.27
chr1_169677205_169677356 0.11 SELL
 selectin L
 3559
 0.24
chr1_145435410_145435648 0.11 TXNIP
 thioredoxin interacting protein
 2940
 0.16
chr20_62270981_62271132 0.11 CTD-3184A7.4
12453
 0.09
chr8_65607910_65608061 0.11 RP11-1D12.1
39031
 0.2
chr1_154315658_154315860 0.11 ENSG00000238365
 .
 4540
 0.12
chr2_68994932_68995083 0.11 ARHGAP25
 Rho GTPase activating protein 25
 6926
 0.26
chr17_75456326_75456913 0.11 SEPT9
 septin 9
 4171
 0.18
chr10_6620632_6620783 0.11 PRKCQ
 protein kinase C, theta
 1494
 0.57
chr2_10522774_10523051 0.11 HPCAL1
 hippocalcin-like 1
 37235
 0.15
chr13_31310422_31310683 0.11 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 907
 0.71
chr17_33568427_33568649 0.11 RP11-799D4.4
1444
 0.28
chr17_1478951_1479102 0.11 PITPNA
 phosphatidylinositol transfer protein, alpha
 12916
 0.11
chr21_35322492_35322643 0.11 LINC00649
 long intergenic non-protein coding RNA 649
 1337
 0.41
chr22_50523207_50523373 0.11 MLC1
 megalencephalic leukoencephalopathy with subcortical cysts 1
 398
 0.79
chr19_5132131_5132282 0.11 CTC-482H14.5
45924
 0.14
chr14_77013139_77013290 0.11 ESRRB
 estrogen-related receptor beta
 139333
 0.04
chrX_70331169_70331370 0.11 IL2RG
 interleukin 2 receptor, gamma
 29
 0.95
chr7_127749300_127749451 0.11 ENSG00000207588
 .
 27462
 0.2
chr2_113932645_113932882 0.11 AC016683.5
151
 0.91
chr18_5294330_5295063 0.11 ZBTB14
 zinc finger and BTB domain containing 14
 127
 0.98
chr6_28108040_28108408 0.11 ZKSCAN8
 zinc finger with KRAB and SCAN domains 8
 1492
 0.26
chr12_112449785_112449936 0.11 TMEM116
 transmembrane protein 116
 1055
 0.37
chr7_55636821_55636978 0.11 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 2662
 0.29
chr7_43690953_43691104 0.11 COA1
 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
 1133
 0.55
chr6_11786252_11786455 0.10 ADTRP
 androgen-dependent TFPI-regulating protein
 6492
 0.3
chrX_21391687_21391849 0.10 CNKSR2
 connector enhancer of kinase suppressor of Ras 2
 768
 0.79
chr2_197034753_197035766 0.10 STK17B
 serine/threonine kinase 17b
 465
 0.83
chr10_105670056_105670248 0.10 OBFC1
 oligonucleotide/oligosaccharide-binding fold containing 1
 7275
 0.18
chr9_117149358_117150269 0.10 AKNA
 AT-hook transcription factor
 430
 0.85
chr12_54892329_54892523 0.10 NCKAP1L
 NCK-associated protein 1-like
 142
 0.94
chr7_66459685_66459882 0.10 SBDS
 Shwachman-Bodian-Diamond syndrome
 805
 0.55
chr12_109027255_109027564 0.10 SELPLG
 selectin P ligand
 261
 0.87
chr5_176560848_176561583 0.10 NSD1
 nuclear receptor binding SET domain protein 1
 15
 0.98
chr17_76117639_76118201 0.10 TMC6
 transmembrane channel-like 6
 909
 0.44
chr10_30994119_30994515 0.10 SVILP1
 supervillin pseudogene 1
 9467
 0.26
chr1_154924890_154925041 0.10 PBXIP1
 pre-B-cell leukemia homeobox interacting protein 1
 3615
 0.1
chr7_152373399_152373635 0.10 XRCC2
 X-ray repair complementing defective repair in Chinese hamster cells 2
 267
 0.92
chr6_91005254_91005982 0.10 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 843
 0.69
chr6_42408755_42408959 0.10 TRERF1
 transcriptional regulating factor 1
 10142
 0.2
chr14_90863482_90863819 0.10 CALM1
 calmodulin 1 (phosphorylase kinase, delta)
 250
 0.92
chr14_22471633_22471925 0.10 ENSG00000238634
 .
 139108
 0.04
chr1_2221478_2221737 0.10 RP4-713A8.1
36525
 0.09
chr17_75125901_75126097 0.10 SEC14L1
 SEC14-like 1 (S. cerevisiae)
 2044
 0.33
chr6_159235122_159235362 0.10 EZR-AS1
 EZR antisense RNA 1
 3801
 0.21
chr6_2901280_2901469 0.10 SERPINB9
 serpin peptidase inhibitor, clade B (ovalbumin), member 9
 2140
 0.3
chr4_84034679_84034947 0.10 PLAC8
 placenta-specific 8
 1055
 0.6
chr4_26270650_26270801 0.10 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 3504
 0.38
chr17_40405293_40405444 0.10 RP11-358B23.5
15237
 0.11
chrX_15756367_15757484 0.10 CA5B
 carbonic anhydrase VB, mitochondrial
 532
 0.77
chr6_42739563_42739714 0.10 GLTSCR1L
 GLTSCR1-like
 10127
 0.17
chr2_70321192_70321429 0.10 PCBP1-AS1
 PCBP1 antisense RNA 1
 5332
 0.17
chr13_52108709_52108900 0.10 INTS6-AS1
 INTS6 antisense RNA 1
 6890
 0.15
chrX_130897041_130897446 0.10 ENSG00000200587
 .
 175741
 0.03
chr1_32713939_32714090 0.10 FAM167B
 family with sequence similarity 167, member B
 1180
 0.26
chr11_2321078_2321236 0.10 C11orf21
 chromosome 11 open reading frame 21
 1986
 0.2
chr1_25890351_25890502 0.10 LDLRAP1
 low density lipoprotein receptor adaptor protein 1
 20355
 0.18
chr11_67172347_67172531 0.10 TBC1D10C
 TBC1 domain family, member 10C
 779
 0.35
chr17_6560768_6561014 0.10 ENSG00000264468
 .
 2063
 0.17
chr14_22538566_22539116 0.10 ENSG00000238634
 .
 72046
 0.12
chr8_29324075_29324226 0.10 RP4-676L2.1
113463
 0.06
chr8_82022969_82023806 0.10 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 916
 0.72
chr12_69201397_69201692 0.10 MDM2
 MDM2 oncogene, E3 ubiquitin protein ligase
 412
 0.8
chr17_62982296_62982856 0.09 AMZ2P1
 archaelysin family metallopeptidase 2 pseudogene 1
 12941
 0.15
chr13_114875917_114876068 0.09 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 1697
 0.42
chr15_77289158_77289399 0.09 PSTPIP1
 proline-serine-threonine phosphatase interacting protein 1
 1363
 0.44
chr7_7812087_7812527 0.09 RPA3-AS1
 RPA3 antisense RNA 1
 315
 0.93
chr6_143228096_143228637 0.09 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 37972
 0.2
chr18_48680545_48680786 0.09 MEX3C
 mex-3 RNA binding family member C
 42464
 0.16
chr1_198648140_198648351 0.09 RP11-553K8.5
12055
 0.25
chr5_39197523_39197702 0.09 FYB
 FYN binding protein
 5517
 0.3
chr8_28559464_28559708 0.09 EXTL3-AS1
 EXTL3 antisense RNA 1
 605
 0.51
chr7_8010738_8010889 0.09 AC006042.7
1279
 0.36
chrY_1605029_1605190 0.09 NA
 NA
 > 106
 NA
chr1_28195799_28196249 0.09 THEMIS2
 thymocyte selection associated family member 2
 3031
 0.15
chr13_103498299_103498896 0.09 ERCC5
 excision repair cross-complementing rodent repair deficiency, complementation group 5
 423
 0.79
chr1_6663176_6663786 0.09 KLHL21
 kelch-like family member 21
 420
 0.75
chr1_204379460_204380399 0.09 PPP1R15B
 protein phosphatase 1, regulatory subunit 15B
 990
 0.54
chr1_29242251_29242585 0.09 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
 1327
 0.43
chrX_117632459_117632610 0.09 DOCK11
 dedicator of cytokinesis 11
 2662
 0.35
chr1_144340215_144340417 0.09 AL592284.1
 Protein LOC642441
 578
 0.76
chrX_153166301_153166452 0.09 AVPR2
 arginine vasopressin receptor 2
 3813
 0.11
chr4_144480155_144480513 0.09 SMARCA5-AS1
 SMARCA5 antisense RNA 1
 44546
 0.15
chrX_1655035_1655190 0.09 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 888
 0.64
chr9_134143747_134144006 0.09 FAM78A
 family with sequence similarity 78, member A
 2004
 0.31
chr3_114009980_114010222 0.09 TIGIT
 T cell immunoreceptor with Ig and ITIM domains
 152
 0.96
chr12_92899150_92899489 0.09 ENSG00000238865
 .
 39444
 0.17
chr1_47903753_47903904 0.09 FOXD2
 forkhead box D2
 2139
 0.25
chr8_58504015_58504166 0.09 ENSG00000252057
 .
 34946
 0.24
chr6_143228681_143228886 0.09 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 37555
 0.2
chr17_2700217_2700494 0.09 RAP1GAP2
 RAP1 GTPase activating protein 2
 579
 0.74
chr5_75627068_75627317 0.09 RP11-466P24.6
19905
 0.25
chr20_62368079_62368369 0.09 LIME1
 Lck interacting transmembrane adaptor 1
 229
 0.81
chr19_16438433_16439148 0.09 KLF2
 Kruppel-like factor 2
 3139
 0.19
chr11_107879361_107879512 0.09 CUL5
 cullin 5
 23
 0.98
chr19_5804658_5804817 0.09 DUS3L
 dihydrouridine synthase 3-like (S. cerevisiae)
 13488
 0.08
chr1_151042732_151043215 0.09 GABPB2
 GA binding protein transcription factor, beta subunit 2
 107
 0.58
chr20_43599792_43600332 0.09 STK4
 serine/threonine kinase 4
 4895
 0.16
chr19_4379487_4379638 0.09 SH3GL1
 SH3-domain GRB2-like 1
 727
 0.43
chr22_39547258_39547409 0.09 CBX7
 chromobox homolog 7
 1116
 0.46
chr14_22962722_22962873 0.09 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 6626
 0.11
chr20_42840227_42840385 0.09 OSER1
 oxidative stress responsive serine-rich 1
 875
 0.57
chr1_182289672_182289823 0.09 ENSG00000206764
 .
 6456
 0.27
chr13_19174246_19174726 0.09 ENSG00000223024
 .
 268945
 0.02
chr19_7723134_7723321 0.09 RETN
 resistin
 10703
 0.07
chr15_63502851_63503002 0.09 RAB8B
 RAB8B, member RAS oncogene family
 21121
 0.19
chr10_63753311_63753523 0.09 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 55553
 0.14
chr19_10397706_10398023 0.09 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
 184
 0.83
chr19_55765720_55766271 0.09 PPP6R1
 protein phosphatase 6, regulatory subunit 1
 1142
 0.27
chr6_26366833_26367042 0.09 ENSG00000215979
 .
 1157
 0.26
chr19_13215586_13215874 0.09 LYL1
 lymphoblastic leukemia derived sequence 1
 1755
 0.21
chr6_117870110_117870478 0.09 GOPC
 golgi-associated PDZ and coiled-coil motif containing
 53233
 0.12
chr5_176839896_176840051 0.09 F12
 coagulation factor XII (Hageman factor)
 3396
 0.12
chr1_249156955_249157464 0.09 AL672294.1
3846
 0.16
chr17_39822401_39822869 0.09 EIF1
 eukaryotic translation initiation factor 1
 22504
 0.09
chr19_54873932_54874135 0.09 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 1477
 0.26
chr19_17982701_17982908 0.09 SLC5A5
 solute carrier family 5 (sodium/iodide cotransporter), member 5
 22
 0.96
chr14_52327497_52328482 0.09 GNG2
 guanine nucleotide binding protein (G protein), gamma 2
 53
 0.98
chr2_43448437_43448588 0.09 ZFP36L2
 ZFP36 ring finger protein-like 2
 5236
 0.25
chr5_118644851_118645262 0.09 ENSG00000243333
 .
 2730
 0.28
chr20_3779530_3779768 0.09 CDC25B
 cell division cycle 25B
 2571
 0.18
chr9_126101731_126102049 0.09 CRB2
 crumbs homolog 2 (Drosophila)
 16559
 0.22
chr2_242557475_242557626 0.09 THAP4
 THAP domain containing 4
 634
 0.62
chr19_9937977_9938220 0.09 FBXL12
 F-box and leucine-rich repeat protein 12
 394
 0.46
chr16_14380439_14380590 0.09 ENSG00000201075
 .
 11152
 0.18
chr3_182511391_182511643 0.09 ATP11B
 ATPase, class VI, type 11B
 226
 0.63
chr4_3304601_3305007 0.09 RGS12
 regulator of G-protein signaling 12
 5958
 0.26
chr6_128293411_128293648 0.08 PTPRK
 protein tyrosine phosphatase, receptor type, K
 35693
 0.18
chr4_122103316_122103738 0.08 ENSG00000252183
 .
 10531
 0.22
chr9_32572870_32573104 0.08 NDUFB6
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
 170
 0.93
chr16_30220301_30220755 0.08 RP11-347C12.3
 Uncharacterized protein
 2025
 0.15
chr1_6525547_6525781 0.08 TNFRSF25
 tumor necrosis factor receptor superfamily, member 25
 26
 0.96
chr12_50064807_50065013 0.08 FMNL3
 formin-like 3
 36093
 0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF3_MYOG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.2 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.5 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.3 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0033233 regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.7 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0034393 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0032608 interferon-beta production(GO:0032608)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0021612 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) anatomical structure arrangement(GO:0048532)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.0 GO:0001652 granular component(GO:0001652)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)