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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TCF3_MYOG

Z-value: 0.35

Motif logo

Transcription factors associated with TCF3_MYOG

Gene Symbol	Gene ID	Gene Info
TCF3 Ensembl NCBI GeneCards UniProt	ENSG00000071564.10	TCF3
MYOG Ensembl NCBI GeneCards UniProt	ENSG00000122180.4	MYOG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
MYOG	chr1_203044604_203044831	10447	0.130208	-0.49	1.8e-01	Click!
MYOG	chr1_203052021_203052172	3068	0.179211	-0.35	3.5e-01	Click!
MYOG	chr1_203044981_203045143	10102	0.130813	-0.21	5.9e-01	Click!
MYOG	chr1_203045268_203045454	9803	0.131356	-0.06	8.7e-01	Click!
TCF3	chr19_1682723_1682874	30194	0.105053	-0.62	7.7e-02	Click!
TCF3	chr19_1675853_1676228	23436	0.114431	-0.57	1.1e-01	Click!
TCF3	chr19_1653201_1653411	702	0.573603	0.42	2.6e-01	Click!
TCF3	chr19_1701461_1701612	48932	0.076519	-0.41	2.7e-01	Click!
TCF3	chr19_1650811_1650962	142	0.935336	-0.39	3.0e-01	Click!

Activity of the TCF3_MYOG motif across conditions

Conditions sorted by the z-value of the TCF3_MYOG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_160681036_160681588	0.33	CD48	CD48 molecule	281	0.89
chr22_42177525_42177912	0.25	MEI1	meiosis inhibitor 1	21	0.96
chr22_21738155_21738638	0.22	RIMBP3B	RIMS binding protein 3B	733	0.51
chr22_20460794_20461266	0.21	RIMBP3	RIMS binding protein 3	756	0.52
chr11_84028149_84028546	0.20	DLG2	discs, large homolog 2 (Drosophila)	35	0.99
chr12_133006842_133006993	0.20	MUC8	mucin 8	43809	0.14
chrX_13103844_13104411	0.20	FAM9C	family with sequence similarity 9, member C	41326	0.19
chr2_240188602_240189192	0.19	ENSG00000265215	.	38260	0.14
chr22_21904755_21905186	0.19	RIMBP3C	RIMS binding protein 3C	150	0.88
chr15_60419498_60420019	0.18	FOXB1	forkhead box B1	123337	0.06
chr2_25562492_25562759	0.18	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	2129	0.34
chr5_169729652_169729829	0.18	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	4509	0.25
chr5_150535420_150535844	0.18	ANXA6	annexin A6	1676	0.39
chr19_3180678_3181240	0.17	S1PR4	sphingosine-1-phosphate receptor 4	2223	0.2
chr11_118212224_118212431	0.17	CD3D	CD3d molecule, delta (CD3-TCR complex)	675	0.54
chr1_65530319_65530470	0.17	ENSG00000199135	.	6203	0.2
chr11_65407442_65407916	0.17	SIPA1	signal-induced proliferation-associated 1	87	0.92
chr20_56195172_56195527	0.16	ZBP1	Z-DNA binding protein 1	101	0.98
chr13_52398191_52398536	0.16	RP11-327P2.5		19930	0.17
chr10_73531816_73531986	0.16	C10orf54	chromosome 10 open reading frame 54	1354	0.44
chr10_104420612_104420763	0.16	TRIM8	tripartite motif containing 8	16043	0.16
chr18_2967390_2967541	0.16	RP11-737O24.1		449	0.78
chr3_50646848_50647098	0.16	CISH	cytokine inducible SH2-containing protein	2230	0.22
chr19_48835948_48836196	0.15	EMP3	epithelial membrane protein 3	7207	0.11
chr13_75900551_75900966	0.15	TBC1D4	TBC1 domain family, member 4	14909	0.24
chr18_43266884_43267229	0.15	SLC14A2	solute carrier family 14 (urea transporter), member 2	20949	0.17
chr3_114832402_114832553	0.15	ZBTB20	zinc finger and BTB domain containing 20	33641	0.25
chrX_44203680_44203969	0.15	EFHC2	EF-hand domain (C-terminal) containing 2	906	0.71
chr20_35274684_35274835	0.15	SLA2	Src-like-adaptor 2	140	0.94
chr2_220408420_220408618	0.14	CHPF	chondroitin polymerizing factor	10	0.62
chr14_91840122_91840324	0.14	ENSG00000265856	.	40166	0.15
chrY_15863423_15864046	0.14	KALP	Kallmann syndrome sequence pseudogene	198	0.96
chr8_128988445_128988635	0.14	ENSG00000221771	.	15661	0.16
chr7_150434707_150435064	0.14	GIMAP5	GTPase, IMAP family member 5	449	0.8
chr6_144655565_144656031	0.14	RP1-91J24.3		1361	0.51
chr1_244215459_244215610	0.14	ZBTB18	zinc finger and BTB domain containing 18	949	0.61
chr7_72300733_72300925	0.14	SBDSP1	Shwachman-Bodian-Diamond syndrome pseudogene 1	594	0.6
chr11_2323777_2324127	0.14	TSPAN32	tetraspanin 32	1	0.92
chr7_150148052_150148382	0.14	GIMAP8	GTPase, IMAP family member 8	499	0.78
chr17_4615541_4615774	0.14	ARRB2	arrestin, beta 2	1663	0.18
chr20_50158140_50158637	0.14	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	870	0.72
chr22_24039509_24039689	0.14	RGL4	ral guanine nucleotide dissociation stimulator-like 4	928	0.45
chr6_32813075_32813316	0.13	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9	582	0.44
chr16_27413508_27414237	0.13	IL21R	interleukin 21 receptor	377	0.88
chr4_16219327_16219478	0.13	TAPT1	transmembrane anterior posterior transformation 1	8692	0.2
chr14_106854492_106854843	0.13	IGHV3-37	immunoglobulin heavy variable 3-37 (pseudogene)	1641	0.1
chr17_80260072_80260536	0.13	CD7	CD7 molecule	15124	0.1
chr16_28996496_28996848	0.13	LAT	linker for activation of T cells	11	0.94
chr15_21995486_21996039	0.13	DKFZP547L112		15608	0.19
chr15_75082884_75083035	0.13	ENSG00000264386	.	1861	0.2
chr10_129985976_129986188	0.13	MKI67	marker of proliferation Ki-67	61433	0.15
chr1_209930383_209930698	0.12	TRAF3IP3	TRAF3 interacting protein 3	1016	0.45
chrX_153267742_153268222	0.12	IRAK1	interleukin-1 receptor-associated kinase 1	11715	0.09
chr15_29211815_29211966	0.12	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2	320	0.92
chr1_225654970_225655492	0.12	RP11-496N12.6		2186	0.34
chr22_32598633_32598888	0.12	RFPL2	ret finger protein-like 2	704	0.6
chr17_43305439_43305590	0.12	CTD-2020K17.1		5925	0.1
chr11_1874347_1875032	0.12	LSP1	lymphocyte-specific protein 1	489	0.65
chr2_225803456_225803653	0.12	DOCK10	dedicator of cytokinesis 10	8228	0.3
chr15_20988807_20989390	0.12	AC012414.1	Uncharacterized protein	15589	0.17
chr17_8868395_8868683	0.12	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	485	0.85
chr11_67186046_67186291	0.12	PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	2484	0.1
chr22_22292604_22292980	0.12	LL22NC03-86G7.1		127	0.51
chr17_38720511_38720770	0.12	CCR7	chemokine (C-C motif) receptor 7	1071	0.49
chr20_62369505_62369786	0.12	RP4-583P15.14		22	0.92
chr11_67176924_67177082	0.12	TBC1D10C	TBC1 domain family, member 10C	5343	0.07
chr6_31238477_31238986	0.12	HLA-C	major histocompatibility complex, class I, C	1115	0.41
chr17_4617667_4617818	0.12	ARRB2	arrestin, beta 2	1142	0.27
chr1_169677205_169677356	0.11	SELL	selectin L	3559	0.24
chr1_145435410_145435648	0.11	TXNIP	thioredoxin interacting protein	2940	0.16
chr20_62270981_62271132	0.11	CTD-3184A7.4		12453	0.09
chr8_65607910_65608061	0.11	RP11-1D12.1		39031	0.2
chr1_154315658_154315860	0.11	ENSG00000238365	.	4540	0.12
chr2_68994932_68995083	0.11	ARHGAP25	Rho GTPase activating protein 25	6926	0.26
chr17_75456326_75456913	0.11	SEPT9	septin 9	4171	0.18
chr10_6620632_6620783	0.11	PRKCQ	protein kinase C, theta	1494	0.57
chr2_10522774_10523051	0.11	HPCAL1	hippocalcin-like 1	37235	0.15
chr13_31310422_31310683	0.11	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	907	0.71
chr17_33568427_33568649	0.11	RP11-799D4.4		1444	0.28
chr17_1478951_1479102	0.11	PITPNA	phosphatidylinositol transfer protein, alpha	12916	0.11
chr21_35322492_35322643	0.11	LINC00649	long intergenic non-protein coding RNA 649	1337	0.41
chr22_50523207_50523373	0.11	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1	398	0.79
chr19_5132131_5132282	0.11	CTC-482H14.5		45924	0.14
chr14_77013139_77013290	0.11	ESRRB	estrogen-related receptor beta	139333	0.04
chrX_70331169_70331370	0.11	IL2RG	interleukin 2 receptor, gamma	29	0.95
chr7_127749300_127749451	0.11	ENSG00000207588	.	27462	0.2
chr2_113932645_113932882	0.11	AC016683.5		151	0.91
chr18_5294330_5295063	0.11	ZBTB14	zinc finger and BTB domain containing 14	127	0.98
chr6_28108040_28108408	0.11	ZKSCAN8	zinc finger with KRAB and SCAN domains 8	1492	0.26
chr12_112449785_112449936	0.11	TMEM116	transmembrane protein 116	1055	0.37
chr7_55636821_55636978	0.11	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	2662	0.29
chr7_43690953_43691104	0.11	COA1	cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)	1133	0.55
chr6_11786252_11786455	0.10	ADTRP	androgen-dependent TFPI-regulating protein	6492	0.3
chrX_21391687_21391849	0.10	CNKSR2	connector enhancer of kinase suppressor of Ras 2	768	0.79
chr2_197034753_197035766	0.10	STK17B	serine/threonine kinase 17b	465	0.83
chr10_105670056_105670248	0.10	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	7275	0.18
chr9_117149358_117150269	0.10	AKNA	AT-hook transcription factor	430	0.85
chr12_54892329_54892523	0.10	NCKAP1L	NCK-associated protein 1-like	142	0.94
chr7_66459685_66459882	0.10	SBDS	Shwachman-Bodian-Diamond syndrome	805	0.55
chr12_109027255_109027564	0.10	SELPLG	selectin P ligand	261	0.87
chr5_176560848_176561583	0.10	NSD1	nuclear receptor binding SET domain protein 1	15	0.98
chr17_76117639_76118201	0.10	TMC6	transmembrane channel-like 6	909	0.44
chr10_30994119_30994515	0.10	SVILP1	supervillin pseudogene 1	9467	0.26
chr1_154924890_154925041	0.10	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	3615	0.1
chr7_152373399_152373635	0.10	XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	267	0.92
chr6_91005254_91005982	0.10	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	843	0.69
chr6_42408755_42408959	0.10	TRERF1	transcriptional regulating factor 1	10142	0.2
chr14_90863482_90863819	0.10	CALM1	calmodulin 1 (phosphorylase kinase, delta)	250	0.92
chr14_22471633_22471925	0.10	ENSG00000238634	.	139108	0.04
chr1_2221478_2221737	0.10	RP4-713A8.1		36525	0.09
chr17_75125901_75126097	0.10	SEC14L1	SEC14-like 1 (S. cerevisiae)	2044	0.33
chr6_159235122_159235362	0.10	EZR-AS1	EZR antisense RNA 1	3801	0.21
chr6_2901280_2901469	0.10	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	2140	0.3
chr4_84034679_84034947	0.10	PLAC8	placenta-specific 8	1055	0.6
chr4_26270650_26270801	0.10	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	3504	0.38
chr17_40405293_40405444	0.10	RP11-358B23.5		15237	0.11
chrX_15756367_15757484	0.10	CA5B	carbonic anhydrase VB, mitochondrial	532	0.77
chr6_42739563_42739714	0.10	GLTSCR1L	GLTSCR1-like	10127	0.17
chr2_70321192_70321429	0.10	PCBP1-AS1	PCBP1 antisense RNA 1	5332	0.17
chr13_52108709_52108900	0.10	INTS6-AS1	INTS6 antisense RNA 1	6890	0.15
chrX_130897041_130897446	0.10	ENSG00000200587	.	175741	0.03
chr1_32713939_32714090	0.10	FAM167B	family with sequence similarity 167, member B	1180	0.26
chr11_2321078_2321236	0.10	C11orf21	chromosome 11 open reading frame 21	1986	0.2
chr1_25890351_25890502	0.10	LDLRAP1	low density lipoprotein receptor adaptor protein 1	20355	0.18
chr11_67172347_67172531	0.10	TBC1D10C	TBC1 domain family, member 10C	779	0.35
chr17_6560768_6561014	0.10	ENSG00000264468	.	2063	0.17
chr14_22538566_22539116	0.10	ENSG00000238634	.	72046	0.12
chr8_29324075_29324226	0.10	RP4-676L2.1		113463	0.06
chr8_82022969_82023806	0.10	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	916	0.72
chr12_69201397_69201692	0.10	MDM2	MDM2 oncogene, E3 ubiquitin protein ligase	412	0.8
chr17_62982296_62982856	0.09	AMZ2P1	archaelysin family metallopeptidase 2 pseudogene 1	12941	0.15
chr13_114875917_114876068	0.09	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	1697	0.42
chr15_77289158_77289399	0.09	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	1363	0.44
chr7_7812087_7812527	0.09	RPA3-AS1	RPA3 antisense RNA 1	315	0.93
chr6_143228096_143228637	0.09	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	37972	0.2
chr18_48680545_48680786	0.09	MEX3C	mex-3 RNA binding family member C	42464	0.16
chr1_198648140_198648351	0.09	RP11-553K8.5		12055	0.25
chr5_39197523_39197702	0.09	FYB	FYN binding protein	5517	0.3
chr8_28559464_28559708	0.09	EXTL3-AS1	EXTL3 antisense RNA 1	605	0.51
chr7_8010738_8010889	0.09	AC006042.7		1279	0.36
chrY_1605029_1605190	0.09	NA	NA	> 10⁶	NA
chr1_28195799_28196249	0.09	THEMIS2	thymocyte selection associated family member 2	3031	0.15
chr13_103498299_103498896	0.09	ERCC5	excision repair cross-complementing rodent repair deficiency, complementation group 5	423	0.79
chr1_6663176_6663786	0.09	KLHL21	kelch-like family member 21	420	0.75
chr1_204379460_204380399	0.09	PPP1R15B	protein phosphatase 1, regulatory subunit 15B	990	0.54
chr1_29242251_29242585	0.09	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	1327	0.43
chrX_117632459_117632610	0.09	DOCK11	dedicator of cytokinesis 11	2662	0.35
chr1_144340215_144340417	0.09	AL592284.1	Protein LOC642441	578	0.76
chrX_153166301_153166452	0.09	AVPR2	arginine vasopressin receptor 2	3813	0.11
chr4_144480155_144480513	0.09	SMARCA5-AS1	SMARCA5 antisense RNA 1	44546	0.15
chrX_1655035_1655190	0.09	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	888	0.64
chr9_134143747_134144006	0.09	FAM78A	family with sequence similarity 78, member A	2004	0.31
chr3_114009980_114010222	0.09	TIGIT	T cell immunoreceptor with Ig and ITIM domains	152	0.96
chr12_92899150_92899489	0.09	ENSG00000238865	.	39444	0.17
chr1_47903753_47903904	0.09	FOXD2	forkhead box D2	2139	0.25
chr8_58504015_58504166	0.09	ENSG00000252057	.	34946	0.24
chr6_143228681_143228886	0.09	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	37555	0.2
chr17_2700217_2700494	0.09	RAP1GAP2	RAP1 GTPase activating protein 2	579	0.74
chr5_75627068_75627317	0.09	RP11-466P24.6		19905	0.25
chr20_62368079_62368369	0.09	LIME1	Lck interacting transmembrane adaptor 1	229	0.81
chr19_16438433_16439148	0.09	KLF2	Kruppel-like factor 2	3139	0.19
chr11_107879361_107879512	0.09	CUL5	cullin 5	23	0.98
chr19_5804658_5804817	0.09	DUS3L	dihydrouridine synthase 3-like (S. cerevisiae)	13488	0.08
chr1_151042732_151043215	0.09	GABPB2	GA binding protein transcription factor, beta subunit 2	107	0.58
chr20_43599792_43600332	0.09	STK4	serine/threonine kinase 4	4895	0.16
chr19_4379487_4379638	0.09	SH3GL1	SH3-domain GRB2-like 1	727	0.43
chr22_39547258_39547409	0.09	CBX7	chromobox homolog 7	1116	0.46
chr14_22962722_22962873	0.09	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	6626	0.11
chr20_42840227_42840385	0.09	OSER1	oxidative stress responsive serine-rich 1	875	0.57
chr1_182289672_182289823	0.09	ENSG00000206764	.	6456	0.27
chr13_19174246_19174726	0.09	ENSG00000223024	.	268945	0.02
chr19_7723134_7723321	0.09	RETN	resistin	10703	0.07
chr15_63502851_63503002	0.09	RAB8B	RAB8B, member RAS oncogene family	21121	0.19
chr10_63753311_63753523	0.09	ARID5B	AT rich interactive domain 5B (MRF1-like)	55553	0.14
chr19_10397706_10398023	0.09	ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	184	0.83
chr19_55765720_55766271	0.09	PPP6R1	protein phosphatase 6, regulatory subunit 1	1142	0.27
chr6_26366833_26367042	0.09	ENSG00000215979	.	1157	0.26
chr19_13215586_13215874	0.09	LYL1	lymphoblastic leukemia derived sequence 1	1755	0.21
chr6_117870110_117870478	0.09	GOPC	golgi-associated PDZ and coiled-coil motif containing	53233	0.12
chr5_176839896_176840051	0.09	F12	coagulation factor XII (Hageman factor)	3396	0.12
chr1_249156955_249157464	0.09	AL672294.1		3846	0.16
chr17_39822401_39822869	0.09	EIF1	eukaryotic translation initiation factor 1	22504	0.09
chr19_54873932_54874135	0.09	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	1477	0.26
chr19_17982701_17982908	0.09	SLC5A5	solute carrier family 5 (sodium/iodide cotransporter), member 5	22	0.96
chr14_52327497_52328482	0.09	GNG2	guanine nucleotide binding protein (G protein), gamma 2	53	0.98
chr2_43448437_43448588	0.09	ZFP36L2	ZFP36 ring finger protein-like 2	5236	0.25
chr5_118644851_118645262	0.09	ENSG00000243333	.	2730	0.28
chr20_3779530_3779768	0.09	CDC25B	cell division cycle 25B	2571	0.18
chr9_126101731_126102049	0.09	CRB2	crumbs homolog 2 (Drosophila)	16559	0.22
chr2_242557475_242557626	0.09	THAP4	THAP domain containing 4	634	0.62
chr19_9937977_9938220	0.09	FBXL12	F-box and leucine-rich repeat protein 12	394	0.46
chr16_14380439_14380590	0.09	ENSG00000201075	.	11152	0.18
chr3_182511391_182511643	0.09	ATP11B	ATPase, class VI, type 11B	226	0.63
chr4_3304601_3305007	0.09	RGS12	regulator of G-protein signaling 12	5958	0.26
chr6_128293411_128293648	0.08	PTPRK	protein tyrosine phosphatase, receptor type, K	35693	0.18
chr4_122103316_122103738	0.08	ENSG00000252183	.	10531	0.22
chr9_32572870_32573104	0.08	NDUFB6	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa	170	0.93
chr16_30220301_30220755	0.08	RP11-347C12.3	Uncharacterized protein	2025	0.15
chr1_6525547_6525781	0.08	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	26	0.96
chr12_50064807_50065013	0.08	FMNL3	formin-like 3	36093	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF3_MYOG

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0033622	integrin activation(GO:0033622)
0.3	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.2	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.2	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.3	GO:0007141	male meiosis I(GO:0007141)
0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	GO:0070295	renal water absorption(GO:0070295)
0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.2	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	GO:0015705	iodide transport(GO:0015705)
0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.5	GO:0045576	mast cell activation(GO:0045576)
0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.3	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.1	GO:0033233	regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.1	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	GO:0015840	urea transport(GO:0015840)
0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	GO:0051322	anaphase(GO:0051322)
0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.7	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	GO:0001757	somite specification(GO:0001757)
0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.1	GO:0016322	neuron remodeling(GO:0016322)
0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.1	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	GO:0019322	pentose biosynthetic process(GO:0019322)
0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	GO:0006983	ER overload response(GO:0006983)
0.1	GO:0032608	interferon-beta production(GO:0032608)
0.0	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	GO:0021612	cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) anatomical structure arrangement(GO:0048532)
0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0001652	granular component(GO:0001652)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.0	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.4	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.5	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)