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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TCF7L1

Z-value: 0.70

Motif logo

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
TCF7L1
ENSG00000152284.4 TCF7L1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TCF7L1chr2_85443412_8544356327410.220079-0.836.1e-03Click!
TCF7L1chr2_85465249_85465400245780.1259010.752.1e-02Click!
TCF7L1chr2_85464644_85464795239730.1270880.703.5e-02Click!
TCF7L1chr2_85476158_85476514355900.103205-0.541.3e-01Click!
TCF7L1chr2_85473701_85473852330300.1085650.531.4e-01Click!

Activity of the TCF7L1 motif across conditions

Conditions sorted by the z-value of the TCF7L1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_80279192_80279518 0.28 CD7
 CD7 molecule
 3877
 0.13
chr7_27184642_27184864 0.26 HOXA5
 homeobox A5
 1466
 0.14
chr8_17611273_17611424 0.25 MTUS1
 microtubule associated tumor suppressor 1
 2142
 0.28
chr16_9192642_9192817 0.25 RP11-473I1.9
5976
 0.16
chr4_153194568_153194863 0.25 ENSG00000244544
 .
 9118
 0.23
chr1_192514118_192514603 0.23 RP5-1011O1.2
21987
 0.19
chr1_95015118_95015269 0.23 F3
 coagulation factor III (thromboplastin, tissue factor)
 7837
 0.3
chr7_100223660_100223811 0.22 TFR2
 transferrin receptor 2
 6992
 0.09
chr10_132972880_132973031 0.21 TCERG1L-AS1
 TCERG1L antisense RNA 1
 79474
 0.11
chr10_113590379_113590912 0.20 GPAM
 glycerol-3-phosphate acyltransferase, mitochondrial
 352823
 0.01
chr15_66083482_66084093 0.20 DENND4A
 DENN/MADD domain containing 4A
 675
 0.68
chr16_2975177_2975328 0.20 FLYWCH1
 FLYWCH-type zinc finger 1
 5546
 0.1
chr1_33428156_33429049 0.19 RNF19B
 ring finger protein 19B
 1684
 0.28
chr5_175918974_175919125 0.19 RNF44
 ring finger protein 44
 38597
 0.09
chr9_79637286_79637437 0.19 FOXB2
 forkhead box B2
 2790
 0.39
chr1_159929593_159929744 0.19 SLAMF9
 SLAM family member 9
 5624
 0.12
chr3_73126790_73126941 0.19 ENSG00000238416
 .
 4273
 0.16
chr3_149375959_149376254 0.19 WWTR1-AS1
 WWTR1 antisense RNA 1
 109
 0.66
chr6_130543841_130543992 0.18 SAMD3
 sterile alpha motif domain containing 3
 42
 0.99
chr19_30842754_30842905 0.18 ZNF536
 zinc finger protein 536
 20490
 0.28
chr1_41966637_41966788 0.18 EDN2
 endothelin 2
 16370
 0.19
chr17_63694359_63694510 0.18 CEP112
 centrosomal protein 112kDa
 52408
 0.18
chrX_13185584_13185735 0.18 FAM9C
 family with sequence similarity 9, member C
 122858
 0.05
chr2_100102004_100102155 0.18 REV1
 REV1, polymerase (DNA directed)
 4356
 0.25
chr19_34669041_34669419 0.18 LSM14A
 LSM14A, SCD6 homolog A (S. cerevisiae)
 5667
 0.28
chr20_32613579_32613730 0.17 RALY
 RALY heterogeneous nuclear ribonucleoprotein
 4013
 0.23
chr14_98443744_98443895 0.17 C14orf64
 chromosome 14 open reading frame 64
 564
 0.87
chr8_144576890_144577041 0.17 ZC3H3
 zinc finger CCCH-type containing 3
 13045
 0.1
chr7_150180608_150181504 0.17 GIMAP7
 GTPase, IMAP family member 7
 30862
 0.13
chr14_106000080_106000231 0.17 TMEM121
 transmembrane protein 121
 5194
 0.14
chr6_144672449_144672906 0.17 UTRN
 utrophin
 7440
 0.26
chr20_15982068_15982219 0.17 MACROD2
 MACRO domain containing 2
 15710
 0.31
chr7_139929395_139929688 0.16 ENSG00000199283
 .
 12129
 0.17
chr1_160680712_160681035 0.16 CD48
 CD48 molecule
 720
 0.63
chr12_10328213_10328364 0.16 TMEM52B
 transmembrane protein 52B
 3324
 0.16
chr11_108724912_108725630 0.16 ENSG00000201243
 .
 150973
 0.04
chr1_198621955_198622106 0.16 PTPRC
 protein tyrosine phosphatase, receptor type, C
 13738
 0.23
chr2_192169808_192170004 0.16 MYO1B
 myosin IB
 28295
 0.22
chr10_22625053_22625204 0.16 SPAG6
 sperm associated antigen 6
 9271
 0.15
chr3_13919959_13920372 0.16 WNT7A
 wingless-type MMTV integration site family, member 7A
 1453
 0.48
chr9_135506565_135506716 0.16 DDX31
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
 32247
 0.15
chr3_129468296_129468447 0.15 TMCC1
 transmembrane and coiled-coil domain family 1
 44888
 0.13
chr11_130258989_130259140 0.15 ADAMTS8
 ADAM metallopeptidase with thrombospondin type 1 motif, 8
 39824
 0.16
chr5_132377333_132377484 0.15 HSPA4
 heat shock 70kDa protein 4
 10246
 0.17
chr2_236768694_236768845 0.15 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 23270
 0.24
chrX_77204120_77204271 0.15 PGAM4
 phosphoglycerate mutase family member 4
 20940
 0.16
chr3_66514964_66515132 0.15 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 36308
 0.22
chr1_2384159_2384310 0.15 PLCH2
 phospholipase C, eta 2
 14664
 0.11
chr2_210241109_210241260 0.15 MAP2
 microtubule-associated protein 2
 47598
 0.2
chr6_135504304_135504969 0.15 MYB
 v-myb avian myeloblastosis viral oncogene homolog
 1984
 0.32
chr17_38264116_38264342 0.15 NR1D1
 nuclear receptor subfamily 1, group D, member 1
 7251
 0.12
chr11_134145279_134145568 0.15 GLB1L3
 galactosidase, beta 1-like 3
 1212
 0.41
chr20_62573788_62573939 0.14 ENSG00000207554
 .
 216
 0.73
chr10_61624489_61624640 0.14 CCDC6
 coiled-coil domain containing 6
 41850
 0.19
chr7_129419391_129420014 0.14 ENSG00000207691
 .
 4848
 0.17
chr14_22987127_22987278 0.14 TRAJ15
 T cell receptor alpha joining 15
 11378
 0.1
chr12_6744815_6744999 0.14 LPAR5
 lysophosphatidic acid receptor 5
 706
 0.45
chr10_13732369_13732520 0.14 RP11-295P9.8
7923
 0.13
chr20_56193089_56193240 0.14 ZBP1
 Z-DNA binding protein 1
 2286
 0.35
chr4_7971561_7971846 0.14 AFAP1
 actin filament associated protein 1
 30050
 0.14
chr6_12061250_12061691 0.14 HIVEP1
 human immunodeficiency virus type I enhancer binding protein 1
 45650
 0.18
chrY_14081502_14081653 0.14 ENSG00000265161
 .
 134065
 0.06
chr11_111749891_111750174 0.14 C11orf1
 chromosome 11 open reading frame 1
 84
 0.55
chr2_58250808_58250969 0.14 VRK2
 vaccinia related kinase 2
 22841
 0.23
chr17_37607615_37607816 0.14 MED1
 mediator complex subunit 1
 176
 0.93
chr22_37310111_37310410 0.14 CSF2RB
 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
 585
 0.66
chr10_4728192_4728343 0.14 AKR1E2
 aldo-keto reductase family 1, member E2
 100554
 0.08
chr1_89487830_89488505 0.14 GBP3
 guanylate binding protein 3
 382
 0.8
chr12_40012002_40012194 0.14 ABCD2
 ATP-binding cassette, sub-family D (ALD), member 2
 1455
 0.48
chr1_154979820_154980060 0.14 ZBTB7B
 zinc finger and BTB domain containing 7B
 4645
 0.08
chr15_70250319_70250470 0.14 ENSG00000207965
 .
 121413
 0.06
chr10_124269483_124269634 0.13 HTRA1
 HtrA serine peptidase 1
 3351
 0.27
chr17_28553116_28553267 0.13 SLC6A4
 solute carrier family 6 (neurotransmitter transporter), member 4
 9525
 0.11
chr5_1884051_1884202 0.13 CTD-2194D22.3
46
 0.95
chr14_69158161_69158312 0.13 CTD-2325P2.3
5954
 0.24
chr7_103273793_103274056 0.13 ENSG00000222386
 .
 148938
 0.04
chr6_29932866_29933025 0.13 HLA-A
 major histocompatibility complex, class I, A
 22619
 0.14
chr9_134153488_134153764 0.13 FAM78A
 family with sequence similarity 78, member A
 1692
 0.35
chrX_154417087_154417278 0.13 VBP1
 von Hippel-Lindau binding protein 1
 8102
 0.19
chr2_121716938_121717089 0.13 ENSG00000221321
 .
 75636
 0.11
chr11_44591831_44591982 0.13 CD82
 CD82 molecule
 2722
 0.31
chr10_30675999_30676150 0.13 ENSG00000239625
 .
 20827
 0.15
chr11_64641916_64642067 0.13 EHD1
 EH-domain containing 1
 1147
 0.31
chr1_155101296_155101447 0.13 EFNA1
 ephrin-A1
 1019
 0.27
chr13_46753488_46753737 0.13 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 2847
 0.22
chr19_59071940_59072091 0.13 AC016629.8
1423
 0.18
chrX_40013569_40013864 0.12 BCOR
 BCL6 corepressor
 7834
 0.32
chr19_461771_462005 0.12 SHC2
 SHC (Src homology 2 domain containing) transforming protein 2
 892
 0.42
chr6_55501172_55501323 0.12 HMGCLL1
 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
 57235
 0.17
chr16_30818504_30818674 0.12 ZNF629
 zinc finger protein 629
 20066
 0.08
chr8_70745749_70746362 0.12 RP11-159H10.3
291
 0.62
chr10_30017356_30017507 0.12 SVIL
 supervillin
 7299
 0.24
chr9_101011054_101011278 0.12 TBC1D2
 TBC1 domain family, member 2
 6696
 0.27
chr19_43100043_43100194 0.12 CEACAM8
 carcinoembryonic antigen-related cell adhesion molecule 8
 911
 0.61
chr16_89382358_89382591 0.12 AC137932.6
5067
 0.15
chr17_15851287_15851438 0.12 ADORA2B
 adenosine A2b receptor
 3131
 0.25
chr13_76334632_76334929 0.12 LMO7
 LIM domain 7
 15
 0.99
chr21_43648519_43648670 0.12 ENSG00000223262
 .
 7311
 0.18
chr10_22622036_22622322 0.12 BMI1
 BMI1 polycomb ring finger oncogene
 6731
 0.15
chr7_100488371_100488522 0.12 UFSP1
 UFM1-specific peptidase 1 (non-functional)
 1107
 0.3
chr15_52338021_52338172 0.11 RP11-430B1.1
12192
 0.15
chr12_43681939_43682090 0.11 ENSG00000215993
 .
 3369
 0.39
chr21_39672293_39672488 0.11 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 3542
 0.35
chr3_71775115_71775529 0.11 EIF4E3
 eukaryotic translation initiation factor 4E family member 3
 796
 0.68
chr20_31100174_31100325 0.11 C20orf112
 chromosome 20 open reading frame 112
 1039
 0.53
chr1_111212990_111213454 0.11 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 4433
 0.21
chr11_95187135_95187286 0.11 ENSG00000201204
 .
 19328
 0.28
chr11_128381553_128381704 0.11 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 6339
 0.25
chr1_24828022_24828241 0.11 RCAN3
 RCAN family member 3
 1256
 0.44
chr19_16195500_16195773 0.11 TPM4
 tropomyosin 4
 3103
 0.21
chr7_41922063_41922214 0.11 AC005027.3
177205
 0.03
chr19_4911213_4911907 0.11 ARRDC5
 arrestin domain containing 5
 8681
 0.13
chr7_150655998_150656149 0.11 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 1891
 0.27
chr4_177366271_177366422 0.11 RP11-87F15.2
124737
 0.05
chr1_210407355_210407517 0.11 SERTAD4-AS1
 SERTAD4 antisense RNA 1
 44
 0.97
chr2_204734419_204734570 0.11 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 461
 0.87
chr1_109757024_109757692 0.11 SARS
 seryl-tRNA synthetase
 754
 0.58
chr5_32531847_32531998 0.11 SUB1
 SUB1 homolog (S. cerevisiae)
 2
 0.99
chr3_71834842_71834993 0.11 PROK2
 prokineticin 2
 560
 0.77
chr11_64088050_64088201 0.11 PRDX5
 peroxiredoxin 5
 2471
 0.1
chr14_50988685_50989139 0.11 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
 10278
 0.18
chr13_26042483_26042809 0.11 ATP8A2
 ATPase, aminophospholipid transporter, class I, type 8A, member 2
 467
 0.84
chr1_158624437_158624588 0.11 SPTA1
 spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
 31886
 0.12
chr5_171580625_171580776 0.11 STK10
 serine/threonine kinase 10
 34690
 0.15
chr3_171774780_171774931 0.11 FNDC3B
 fibronectin type III domain containing 3B
 10152
 0.29
chr5_112497806_112497957 0.11 MCC
 mutated in colorectal cancers
 72493
 0.11
chr1_154955826_154956219 0.11 FLAD1
 flavin adenine dinucleotide synthetase 1
 173
 0.86
chr7_45151465_45151735 0.11 TBRG4
 transforming growth factor beta regulator 4
 20
 0.96
chr1_24882080_24882472 0.11 NCMAP
 noncompact myelin associated protein
 326
 0.88
chr15_59576524_59576675 0.11 RP11-429D19.1
13238
 0.15
chr17_39778090_39778241 0.10 KRT17
 keratin 17
 1355
 0.27
chr7_76149676_76149827 0.10 ENSG00000238560
 .
 3171
 0.19
chr22_46971721_46971872 0.10 GRAMD4
 GRAM domain containing 4
 113
 0.97
chr1_52363576_52363890 0.10 ENSG00000265769
 .
 2910
 0.2
chr17_75447598_75448179 0.10 SEPT9
 septin 9
 562
 0.71
chr7_93485635_93485786 0.10 TFPI2
 tissue factor pathway inhibitor 2
 33772
 0.15
chr10_3542796_3543180 0.10 RP11-184A2.3
250271
 0.02
chr7_138619859_138620309 0.10 KIAA1549
 KIAA1549
 15863
 0.22
chr22_45714336_45714978 0.10 FAM118A
 family with sequence similarity 118, member A
 15
 0.98
chr1_2981320_2981471 0.10 LINC00982
 long intergenic non-protein coding RNA 982
 1045
 0.53
chr2_60758991_60759142 0.10 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 21474
 0.21
chr3_174486803_174486954 0.10 NAALADL2
 N-acetylated alpha-linked acidic dipeptidase-like 2
 90192
 0.1
chr2_36796670_36797008 0.10 FEZ2
 fasciculation and elongation protein zeta 2 (zygin II)
 11631
 0.19
chr12_27717509_27717879 0.10 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
 26638
 0.2
chr17_7297534_7297804 0.10 TMEM256-PLSCR3
 TMEM256-PLSCR3 readthrough (NMD candidate)
 76
 0.9
chr15_55559668_55560071 0.10 RAB27A
 RAB27A, member RAS oncogene family
 2585
 0.3
chr2_139273768_139273919 0.10 SPOPL
 speckle-type POZ protein-like
 14472
 0.31
chr7_55637667_55637921 0.10 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 1767
 0.37
chr10_29887628_29887779 0.10 ENSG00000216035
 .
 3572
 0.24
chr8_8154312_8154463 0.10 ALG1L13P
 asparagine-linked glycosylation 1-like 13, pseudogene
 55454
 0.11
chr2_106711904_106712070 0.10 C2orf40
 chromosome 2 open reading frame 40
 29731
 0.2
chr5_176782074_176782225 0.10 RGS14
 regulator of G-protein signaling 14
 2689
 0.14
chr9_12241558_12241709 0.10 ENSG00000222581
 .
 58818
 0.17
chr17_57643262_57643540 0.10 DHX40
 DEAH (Asp-Glu-Ala-His) box polypeptide 40
 417
 0.85
chr2_192176773_192176924 0.10 MYO1B
 myosin IB
 35237
 0.19
chr18_3453699_3454909 0.10 TGIF1
 TGFB-induced factor homeobox 1
 532
 0.8
chrX_19815653_19816006 0.10 SH3KBP1
 SH3-domain kinase binding protein 1
 2040
 0.46
chr2_204801338_204802214 0.10 ICOS
 inducible T-cell co-stimulator
 273
 0.95
chr19_16230354_16230505 0.10 RAB8A
 RAB8A, member RAS oncogene family
 7722
 0.13
chr9_23779204_23779355 0.10 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
 94
 0.99
chr16_3628507_3629057 0.10 NLRC3
 NLR family, CARD domain containing 3
 1381
 0.35
chr8_144591297_144591448 0.10 ZC3H3
 zinc finger CCCH-type containing 3
 1362
 0.27
chr2_45970517_45970668 0.10 U51244.2
67977
 0.12
chr1_205287839_205287990 0.10 NUAK2
 NUAK family, SNF1-like kinase, 2
 2969
 0.23
chr17_80832203_80832354 0.10 TBCD
 tubulin folding cofactor D
 9750
 0.18
chr10_54213744_54213895 0.10 RP11-556E13.1
107046
 0.07
chr17_53785965_53786128 0.10 TMEM100
 transmembrane protein 100
 13113
 0.26
chrY_9769735_9769886 0.09 TSPY5P
 testis specific protein, Y-linked 5, pseudogene
 136950
 0.05
chr11_117857636_117858098 0.09 IL10RA
 interleukin 10 receptor, alpha
 758
 0.66
chr18_11688870_11689119 0.09 GNAL
 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
 39
 0.98
chr17_54671562_54672245 0.09 NOG
 noggin
 843
 0.75
chrY_21729956_21730145 0.09 TXLNG2P
 taxilin gamma 2, pseudogene
 782
 0.7
chr8_22524109_22524260 0.09 BIN3
 bridging integrator 3
 2442
 0.18
chr16_84875483_84875757 0.09 CRISPLD2
 cysteine-rich secretory protein LCCL domain containing 2
 11
 0.98
chr8_17105056_17105444 0.09 VPS37A
 vacuolar protein sorting 37 homolog A (S. cerevisiae)
 497
 0.64
chr5_167249979_167250130 0.09 ENSG00000221741
 .
 47616
 0.14
chr2_122257749_122257900 0.09 CLASP1
 cytoplasmic linker associated protein 1
 3740
 0.25
chr5_133457391_133457692 0.09 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 1768
 0.4
chr7_150414678_150414897 0.09 GIMAP1
 GTPase, IMAP family member 1
 1142
 0.45
chr21_47285255_47285499 0.09 PCBP3
 poly(rC) binding protein 3
 15502
 0.19
chr17_61328641_61328792 0.09 AC037445.1
53570
 0.11
chr4_41938007_41938269 0.09 TMEM33
 transmembrane protein 33
 969
 0.62
chr4_53058800_53058951 0.09 SPATA18
 spermatogenesis associated 18
 141293
 0.05
chr4_40196291_40196444 0.09 RHOH
 ras homolog family member H
 1084
 0.55
chr1_86874016_86874167 0.09 ODF2L
 outer dense fiber of sperm tails 2-like
 12068
 0.21
chr2_119067816_119068522 0.09 INSIG2
 insulin induced gene 2
 222119
 0.02
chr6_130197055_130197206 0.09 TMEM244
 transmembrane protein 244
 14438
 0.28
chr17_56401068_56401219 0.09 BZRAP1-AS1
 BZRAP1 antisense RNA 1
 1668
 0.23
chr1_155053219_155053398 0.09 EFNA3
 ephrin-A3
 1923
 0.15
chr17_38717958_38718109 0.09 CCR7
 chemokine (C-C motif) receptor 7
 768
 0.63
chr3_111851417_111851568 0.09 GCSAM
 germinal center-associated, signaling and motility
 580
 0.52
chrX_153359472_153359623 0.09 MECP2
 methyl CpG binding protein 2 (Rett syndrome)
 2889
 0.2
chr7_27198059_27198210 0.09 HOXA7
 homeobox A7
 579
 0.44
chr19_54384929_54385717 0.09 PRKCG
 protein kinase C, gamma
 130
 0.89
chr17_74495503_74495654 0.09 RHBDF2
 rhomboid 5 homolog 2 (Drosophila)
 1875
 0.2
chr8_29513452_29513654 0.09 ENSG00000221003
 .
 272568
 0.01
chr11_5246641_5246814 0.09 ENSG00000221031
 .
 858
 0.32
chr16_66551368_66551754 0.09 TK2
 thymidine kinase 2, mitochondrial
 3875
 0.13
chr20_30104549_30104700 0.09 HM13
 histocompatibility (minor) 13
 2300
 0.21
chr17_66508156_66508438 0.09 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
 124
 0.97

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TCF7L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.0 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:0003171 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.0 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation