Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TEAD4

Z-value: 2.20

Motif logo

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Transcription factors associated with TEAD4

Gene Symbol Gene ID Gene Info
ENSG00000197905.4 TEAD4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TEAD4chr12_3067299_306745011220.3983880.363.5e-01Click!
TEAD4chr12_3067860_30680505410.6946590.333.8e-01Click!
TEAD4chr12_3067581_30677328400.5150050.324.1e-01Click!
TEAD4chr12_3068510_306866150.968023-0.206.0e-01Click!
TEAD4chr12_3068772_3068976880.957802-0.156.9e-01Click!

Activity of the TEAD4 motif across conditions

Conditions sorted by the z-value of the TEAD4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_91572648_91572799 0.85 DCN
decorin
394
0.91
chr6_148829356_148829537 0.72 ENSG00000223322
.
15930
0.29
chr17_66950763_66951090 0.70 ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
456
0.87
chr4_55095719_55096018 0.60 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
142
0.98
chr6_80520238_80520389 0.56 ENSG00000221470
.
16289
0.28
chr5_172753069_172753220 0.55 STC2
stanniocalcin 2
656
0.71
chr19_38129236_38129387 0.55 ZFP30
ZFP30 zinc finger protein
16319
0.14
chr3_112356424_112356629 0.54 CCDC80
coiled-coil domain containing 80
418
0.88
chr12_91570174_91570436 0.53 DCN
decorin
2024
0.44
chr6_116832868_116833176 0.52 FAM26E
family with sequence similarity 26, member E
213
0.73
chr2_150982202_150982420 0.52 RND3
Rho family GTPase 3
359585
0.01
chr20_35170337_35170534 0.51 MYL9
myosin, light chain 9, regulatory
535
0.71
chr3_29323785_29323954 0.51 RBMS3
RNA binding motif, single stranded interacting protein 3
762
0.71
chr1_85826475_85826626 0.50 DDAH1
dimethylarginine dimethylaminohydrolase 1
43630
0.13
chr6_28457374_28458144 0.50 GPX6
glutathione peroxidase 6 (olfactory)
25805
0.14
chr4_24107639_24107790 0.50 PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
216014
0.02
chr6_44509899_44510345 0.50 ENSG00000266619
.
106744
0.06
chr12_124774068_124774247 0.49 FAM101A
family with sequence similarity 101, member A
447
0.88
chr6_39398889_39399040 0.49 KIF6
kinesin family member 6
125
0.98
chr7_19145980_19146451 0.48 AC003986.6

5882
0.17
chr10_4285370_4285529 0.48 ENSG00000207124
.
271695
0.02
chr11_3403031_3403210 0.48 ZNF195
zinc finger protein 195
2672
0.22
chr10_129985700_129985940 0.48 MKI67
marker of proliferation Ki-67
61171
0.15
chr13_102105024_102105412 0.48 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
200
0.96
chr16_65154468_65154619 0.47 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
1290
0.65
chr2_175187370_175187521 0.46 SP9
Sp9 transcription factor
12229
0.16
chr17_42637074_42637426 0.46 FZD2
frizzled family receptor 2
2325
0.29
chr4_86700818_86700973 0.44 ARHGAP24
Rho GTPase activating protein 24
1036
0.65
chr10_63813819_63813970 0.44 ARID5B
AT rich interactive domain 5B (MRF1-like)
4924
0.3
chr10_14050350_14050950 0.44 FRMD4A
FERM domain containing 4A
118
0.97
chr3_114341689_114341840 0.43 ZBTB20
zinc finger and BTB domain containing 20
1289
0.61
chrX_52862568_52862773 0.42 XAGE5
X antigen family, member 5
21079
0.15
chr1_86094618_86094769 0.42 ENSG00000199934
.
36730
0.15
chrX_34672783_34673035 0.42 TMEM47
transmembrane protein 47
2496
0.45
chr15_49717369_49717525 0.42 FGF7
fibroblast growth factor 7
1990
0.39
chr2_175893407_175893558 0.42 ENSG00000199827
.
1015
0.45
chr5_140857632_140858335 0.41 ENSG00000242020
.
900
0.34
chr1_78441011_78441162 0.41 FUBP1
far upstream element (FUSE) binding protein 1
3659
0.19
chr21_17443452_17443630 0.41 ENSG00000252273
.
35712
0.23
chr12_77309523_77309699 0.41 CSRP2
cysteine and glycine-rich protein 2
36771
0.18
chr21_17567832_17567983 0.41 ENSG00000201025
.
89182
0.1
chr3_100711576_100712203 0.41 ABI3BP
ABI family, member 3 (NESH) binding protein
408
0.89
chr1_94078987_94079138 0.41 BCAR3
breast cancer anti-estrogen resistance 3
592
0.78
chr2_189847184_189847396 0.41 ENSG00000221502
.
4472
0.25
chr22_28144536_28144687 0.41 RP11-375H17.1

32143
0.2
chr3_114169134_114169310 0.40 ZBTB20
zinc finger and BTB domain containing 20
4308
0.3
chr1_164557864_164558015 0.40 PBX1
pre-B-cell leukemia homeobox 1
25897
0.21
chr5_159898024_159898392 0.40 ENSG00000265237
.
3201
0.22
chr12_53985363_53985546 0.39 ATF7
activating transcription factor 7
9351
0.15
chr1_78884908_78885243 0.39 ENSG00000212308
.
44122
0.17
chr13_74702709_74702889 0.39 KLF12
Kruppel-like factor 12
5595
0.34
chr1_17895906_17896057 0.39 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
11067
0.26
chr13_108102804_108102955 0.39 ENSG00000221650
.
80717
0.11
chr6_112192884_112193487 0.39 FYN
FYN oncogene related to SRC, FGR, YES
1055
0.66
chr3_20616495_20616647 0.39 ENSG00000206807
.
67323
0.14
chr10_33240220_33240427 0.38 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
4268
0.33
chr2_204673173_204673324 0.38 ENSG00000206970
.
26488
0.19
chr6_143168347_143168575 0.38 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
10277
0.28
chr8_41004141_41004292 0.38 ENSG00000206867
.
113805
0.06
chr21_27042997_27043148 0.38 JAM2
junctional adhesion molecule 2
31162
0.16
chr6_24584146_24584297 0.37 KIAA0319
KIAA0319
61735
0.09
chr12_91448136_91448287 0.37 KERA
keratocan
3549
0.29
chr6_5498160_5498518 0.37 RP1-232P20.1

40031
0.2
chr1_221165183_221165334 0.37 HLX
H2.0-like homeobox
110674
0.06
chr12_22093789_22093940 0.37 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
303
0.94
chr21_28214648_28215240 0.37 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
393
0.9
chr22_19931502_19931653 0.37 TXNRD2
thioredoxin reductase 2
2244
0.19
chr9_35276443_35276716 0.36 AL160274.1
HCG17281; PRO0038; Uncharacterized protein
84683
0.07
chr10_79151412_79151734 0.36 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
12169
0.24
chr16_87414863_87415370 0.36 FBXO31
F-box protein 31
2247
0.19
chr21_17584847_17584998 0.36 ENSG00000201025
.
72167
0.13
chr2_83792651_83792802 0.36 ENSG00000199295
.
92133
0.1
chr8_49014264_49014415 0.36 UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
60032
0.14
chr4_189776276_189776436 0.36 ENSG00000252275
.
138477
0.05
chr18_13279449_13279641 0.36 LDLRAD4
low density lipoprotein receptor class A domain containing 4
1443
0.44
chr5_65124568_65124720 0.36 NLN
neurolysin (metallopeptidase M3 family)
40454
0.17
chr3_167784999_167785150 0.35 GOLIM4
golgi integral membrane protein 4
28058
0.26
chr20_439845_439996 0.35 TBC1D20
TBC1 domain family, member 20
3277
0.21
chr7_15597655_15597806 0.35 AGMO
alkylglycerol monooxygenase
3910
0.36
chr13_45145551_45145847 0.35 TSC22D1
TSC22 domain family, member 1
4693
0.31
chr14_73357781_73357932 0.35 DPF3
D4, zinc and double PHD fingers, family 3
2940
0.24
chr9_20605014_20605308 0.35 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
16711
0.19
chr17_59479149_59479300 0.35 RP11-332H18.5

1620
0.23
chr8_123101238_123101389 0.35 HAS2-AS1
HAS2 antisense RNA 1
447637
0.01
chrX_139585587_139585739 0.35 SOX3
SRY (sex determining region Y)-box 3
1562
0.53
chr10_14049890_14050132 0.35 FRMD4A
FERM domain containing 4A
521
0.82
chr4_15329290_15329441 0.35 C1QTNF7
C1q and tumor necrosis factor related protein 7
12077
0.26
chr11_14379258_14380093 0.35 RRAS2
related RAS viral (r-ras) oncogene homolog 2
356
0.92
chr1_240501387_240501653 0.35 ENSG00000252317
.
3165
0.32
chr10_65520225_65520376 0.35 REEP3
receptor accessory protein 3
239177
0.02
chr12_88971091_88971358 0.34 KITLG
KIT ligand
3014
0.3
chr5_98118929_98119080 0.34 RGMB
repulsive guidance molecule family member b
9665
0.22
chr5_15500949_15501183 0.34 FBXL7
F-box and leucine-rich repeat protein 7
481
0.89
chr11_132863892_132864419 0.34 OPCML
opioid binding protein/cell adhesion molecule-like
50492
0.18
chr4_7937771_7938061 0.34 AC097381.1

2812
0.26
chr1_119589529_119589758 0.34 WARS2-IT1
WARS2 intronic transcript 1 (non-protein coding)
385
0.9
chr11_12436083_12436234 0.34 PARVA
parvin, alpha
16370
0.24
chr1_193152641_193152821 0.34 B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
3053
0.27
chr12_26163834_26163985 0.34 RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
760
0.72
chr17_2118811_2119625 0.34 AC130689.5

91
0.93
chr5_9698511_9698662 0.34 TAS2R1
taste receptor, type 2, member 1
13726
0.22
chr3_87036535_87037613 0.34 VGLL3
vestigial like 3 (Drosophila)
2778
0.42
chr3_66350036_66350187 0.34 ENSG00000206759
.
6467
0.24
chr16_79802458_79802717 0.34 ENSG00000221330
.
98953
0.09
chr15_96885598_96885825 0.34 ENSG00000222651
.
9221
0.16
chr6_26987323_26987625 0.33 ENSG00000238621
.
640
0.74
chr15_99864560_99864718 0.33 AC022819.2
Uncharacterized protein
4811
0.23
chr10_71950501_71950732 0.33 SAR1A
SAR1 homolog A (S. cerevisiae)
20337
0.17
chr9_75688893_75689044 0.33 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
6390
0.31
chr7_42267308_42267709 0.33 GLI3
GLI family zinc finger 3
188
0.97
chr6_11394166_11394363 0.33 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
11683
0.27
chr12_56329135_56329873 0.33 DGKA
diacylglycerol kinase, alpha 80kDa
114
0.92
chr6_118872690_118872841 0.33 PLN
phospholamban
3304
0.38
chr10_14052381_14052532 0.33 FRMD4A
FERM domain containing 4A
1924
0.38
chr19_19510958_19511314 0.33 CTB-184G21.3

2276
0.22
chr3_16217443_16217716 0.33 GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
1363
0.53
chr1_119589857_119590031 0.33 WARS2-IT1
WARS2 intronic transcript 1 (non-protein coding)
84
0.98
chr3_164911903_164912054 0.33 SLITRK3
SLIT and NTRK-like family, member 3
1812
0.49
chr12_32261770_32262117 0.33 RP11-843B15.2

1481
0.38
chr8_91895980_91896131 0.32 RP11-662G23.1

24587
0.19
chr21_17796711_17796936 0.32 ENSG00000207638
.
114586
0.06
chr3_11550824_11550978 0.32 VGLL4
vestigial like 4 (Drosophila)
59497
0.14
chr11_75378366_75379067 0.32 MAP6
microtubule-associated protein 6
763
0.58
chr11_15962669_15962820 0.32 CTD-3096P4.1

81992
0.11
chr9_99214684_99214835 0.32 HABP4
hyaluronan binding protein 4
2272
0.34
chr14_100434757_100434946 0.32 EVL
Enah/Vasp-like
2935
0.26
chr1_64241295_64241446 0.32 ROR1
receptor tyrosine kinase-like orphan receptor 1
1656
0.5
chr3_157157240_157157391 0.32 PTX3
pentraxin 3, long
2737
0.35
chr14_64375063_64375214 0.32 SYNE2
spectrin repeat containing, nuclear envelope 2
678
0.77
chr5_159510080_159510300 0.32 PWWP2A
PWWP domain containing 2A
36239
0.14
chr21_17790702_17790950 0.32 ENSG00000207638
.
120583
0.06
chr7_556342_556585 0.32 PDGFA
platelet-derived growth factor alpha polypeptide
1682
0.39
chr5_112020339_112020490 0.32 APC
adenomatous polyposis coli
22781
0.23
chr14_55239474_55239625 0.32 SAMD4A
sterile alpha motif domain containing 4A
17998
0.24
chrX_138774922_138775171 0.32 MCF2
MCF.2 cell line derived transforming sequence
731
0.69
chr20_22777018_22777212 0.32 ENSG00000265151
.
63176
0.14
chr9_96819103_96819334 0.31 PTPDC1
protein tyrosine phosphatase domain containing 1
26142
0.21
chr10_69869590_69869741 0.31 MYPN
myopalladin
412
0.85
chr16_27005073_27005435 0.31 RP11-673P17.2

73925
0.12
chr14_53268449_53268728 0.31 GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
10202
0.16
chr22_47241159_47241311 0.31 ENSG00000221672
.
2568
0.36
chr3_158457850_158458001 0.31 RP11-379F4.4

281
0.88
chr7_19308836_19308987 0.31 FERD3L
Fer3-like bHLH transcription factor
123867
0.05
chr2_193015209_193015360 0.31 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
43966
0.2
chr2_63990763_63990914 0.31 ENSG00000221085
.
68169
0.11
chr2_30456555_30456706 0.31 LBH
limb bud and heart development
1584
0.45
chr11_39182817_39182968 0.31 ENSG00000201591
.
99765
0.09
chr6_26342303_26342467 0.31 ENSG00000252399
.
10879
0.09
chr5_42532028_42532179 0.31 GHR
growth hormone receptor
33855
0.24
chr3_29377379_29377667 0.31 ENSG00000216169
.
33389
0.18
chr1_172327450_172327703 0.31 ENSG00000206684
.
8104
0.18
chr1_196621837_196622284 0.31 CFH
complement factor H
874
0.67
chr6_23003728_23003960 0.31 ENSG00000207394
.
121471
0.07
chr13_30276703_30277107 0.30 SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
107080
0.07
chr5_168839841_168839992 0.30 SLIT3
slit homolog 3 (Drosophila)
111783
0.06
chr17_48858634_48858982 0.30 LUC7L3
LUC7-like 3 (S. cerevisiae)
34828
0.11
chr7_90794067_90794435 0.30 FZD1
frizzled family receptor 1
99532
0.09
chr3_188840890_188841041 0.30 TPRG1
tumor protein p63 regulated 1
23055
0.27
chr10_24498389_24498682 0.30 KIAA1217
KIAA1217
433
0.9
chr4_71587677_71588145 0.30 RUFY3
RUN and FYVE domain containing 3
183
0.92
chr16_54969072_54969449 0.30 IRX5
iroquois homeobox 5
3276
0.4
chr13_76444739_76444999 0.30 C13orf45
chromosome 13 open reading frame 45
318
0.9
chr19_16493261_16493427 0.30 ENSG00000243745
.
16426
0.13
chr9_102130669_102130820 0.30 ENSG00000222337
.
84440
0.09
chr10_30981387_30981538 0.30 SVILP1
supervillin pseudogene 1
3388
0.32
chr16_48478898_48479145 0.30 RP11-44I10.6

3288
0.21
chr6_121869662_121869813 0.30 ENSG00000201379
.
5965
0.25
chr17_750320_750517 0.30 NXN
nucleoredoxin
16919
0.14
chr13_94186434_94186585 0.30 ENSG00000252365
.
165296
0.04
chr18_43169182_43169490 0.30 SLC14A2
solute carrier family 14 (urea transporter), member 2
25430
0.19
chr12_125170011_125170375 0.29 NCOR2
nuclear receptor corepressor 2
118183
0.06
chr2_182182084_182182235 0.29 ENSG00000266705
.
11780
0.3
chr14_52328782_52328973 0.29 GNG2
guanine nucleotide binding protein (G protein), gamma 2
835
0.65
chr6_148842248_148842399 0.29 ENSG00000223322
.
3053
0.4
chr3_15724598_15724749 0.29 ENSG00000264354
.
14205
0.18
chr7_19135945_19136096 0.29 AC003986.6

16077
0.16
chr6_39850892_39851043 0.29 RP11-61I13.3

3377
0.29
chr10_133793669_133793880 0.29 BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
1653
0.46
chr2_44404368_44404519 0.29 PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
8394
0.18
chr12_112860465_112860616 0.29 PTPN11
protein tyrosine phosphatase, non-receptor type 11
3822
0.22
chr20_43211444_43211668 0.29 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
366
0.85
chr1_161129281_161130077 0.29 USP21
ubiquitin specific peptidase 21
352
0.52
chr6_20497460_20497742 0.29 ENSG00000201683
.
2805
0.26
chr12_118626563_118627015 0.29 TAOK3
TAO kinase 3
1538
0.42
chr8_116672519_116672670 0.29 TRPS1
trichorhinophalangeal syndrome I
1311
0.63
chr5_71544123_71544318 0.29 ENSG00000244748
.
66295
0.09
chr7_47662641_47662792 0.29 C7orf65
chromosome 7 open reading frame 65
32126
0.2
chr12_18449386_18449629 0.29 PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
14529
0.31
chr17_65474283_65474491 0.29 ENSG00000207688
.
6782
0.16
chr7_17344121_17344405 0.29 AC003075.4

5282
0.24
chr17_2142192_2142344 0.28 SMG6
SMG6 nonsense mediated mRNA decay factor
1217
0.33
chr4_170175719_170175897 0.28 SH3RF1
SH3 domain containing ring finger 1
15300
0.25
chr14_54686717_54686976 0.28 CDKN3
cyclin-dependent kinase inhibitor 3
176827
0.03
chr10_3570320_3570471 0.28 RP11-184A2.3

222864
0.02
chr3_143528390_143528541 0.28 SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
38835
0.22
chr11_35413519_35413670 0.28 RP4-683L5.1

27010
0.18
chr17_55655032_55655337 0.28 RP11-118E18.4

30589
0.16
chr4_77356777_77357012 0.28 SHROOM3
shroom family member 3
641
0.68
chr7_45959503_45959698 0.28 IGFBP3
insulin-like growth factor binding protein 3
1250
0.48
chr16_8894210_8894380 0.28 PMM2
phosphomannomutase 2
2571
0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TEAD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.9 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.1 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.2 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.3 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.3 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:1904238 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.1 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.4 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.3 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.1 GO:0070091 glucagon secretion(GO:0070091)
0.1 0.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.5 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.2 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.2 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.2 GO:0034393 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.7 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.2 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.8 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.2 GO:0007619 courtship behavior(GO:0007619)
0.0 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.2 GO:0002857 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.2 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 1.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.0 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.1 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.2 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.1 GO:0060033 Mullerian duct regression(GO:0001880) anatomical structure regression(GO:0060033)
0.0 0.0 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.0 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.0 GO:0032825 natural killer cell differentiation(GO:0001779) regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.4 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0045822 negative regulation of heart contraction(GO:0045822)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0010665 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.0 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.7 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:1904063 negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.0 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)
0.0 0.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.2 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.0 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.0 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.0 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.0 0.0 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:1904427 positive regulation of calcium ion transmembrane transport(GO:1904427)
0.0 0.6 GO:0007612 learning(GO:0007612)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0007625 grooming behavior(GO:0007625)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0071688 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.0 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.0 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0072109 renal system vasculature development(GO:0061437) kidney vasculature development(GO:0061440) glomerulus vasculature development(GO:0072012) glomerular mesangium development(GO:0072109)
0.0 0.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.0 GO:0060438 trachea development(GO:0060438)
0.0 0.0 GO:0006273 lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.0 GO:0051588 regulation of neurotransmitter transport(GO:0051588)
0.0 0.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0070875 positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.1 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.0 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0003157 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.0 GO:0080111 DNA demethylation(GO:0080111)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0071437 invadopodium(GO:0071437)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 1.3 GO:0030016 myofibril(GO:0030016)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.2 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 2.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 2.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0009374 biotin binding(GO:0009374)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.0 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint