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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TFAP2B

Z-value: 1.36

Motif logo

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.8 TFAP2B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TFAP2Bchr6_50812700_50812851263360.2674310.791.1e-02Click!
TFAP2Bchr6_50788009_5078816016450.5436660.732.5e-02Click!
TFAP2Bchr6_50811539_50811690251750.2710900.675.0e-02Click!
TFAP2Bchr6_50817900_50818051315360.2505230.655.9e-02Click!
TFAP2Bchr6_50810973_50811124246090.2728530.656.0e-02Click!

Activity of the TFAP2B motif across conditions

Conditions sorted by the z-value of the TFAP2B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_48712666_48713008 0.76 ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
619
0.6
chr1_34628677_34628828 0.75 CSMD2
CUB and Sushi multiple domains 2
2123
0.29
chr1_956379_957022 0.73 AGRN
agrin
1197
0.27
chr6_54711000_54712080 0.72 FAM83B
family with sequence similarity 83, member B
29
0.98
chr22_44756680_44757093 0.70 RP1-32I10.10
Uncharacterized protein
4545
0.29
chr17_5371546_5372510 0.63 DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
40
0.96
chr14_65171132_65172314 0.61 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
408
0.88
chr8_22027174_22027581 0.61 BMP1
bone morphogenetic protein 1
4577
0.12
chr7_150779695_150780926 0.60 TMUB1
transmembrane and ubiquitin-like domain containing 1
9
0.94
chr4_1035336_1035962 0.60 FGFRL1
fibroblast growth factor receptor-like 1
29410
0.11
chr3_137486919_137487668 0.59 SOX14
SRY (sex determining region Y)-box 14
3714
0.37
chr17_48137700_48137955 0.58 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
4023
0.16
chr19_5339568_5339818 0.57 PTPRS
protein tyrosine phosphatase, receptor type, S
1121
0.59
chr15_40531754_40531905 0.56 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
208
0.89
chr5_131594297_131594770 0.56 PDLIM4
PDZ and LIM domain 4
1133
0.45
chr12_112818867_112820166 0.56 HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
380
0.87
chr17_37895722_37895926 0.55 GRB7
growth factor receptor-bound protein 7
396
0.76
chr2_241949003_241950045 0.54 AC093585.6

637
0.62
chr15_99192776_99194432 0.54 IGF1R
insulin-like growth factor 1 receptor
1331
0.47
chr3_53106938_53107738 0.54 ENSG00000266635
.
20324
0.16
chr3_128207705_128209147 0.54 RP11-475N22.4

326
0.79
chr2_110872434_110873339 0.53 MALL
mal, T-cell differentiation protein-like
713
0.63
chr4_187025490_187026623 0.53 FAM149A
family with sequence similarity 149, member A
175
0.94
chr8_23260918_23261191 0.53 LOXL2
lysyl oxidase-like 2
535
0.78
chr2_83156543_83156694 0.52 ENSG00000201311
.
622326
0.0
chr19_4584366_4584890 0.52 SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
24808
0.09
chr4_164265662_164265856 0.52 NPY1R
neuropeptide Y receptor Y1
225
0.76
chr10_11784750_11785238 0.51 ECHDC3
enoyl CoA hydratase domain containing 3
549
0.83
chr19_51161641_51162497 0.50 C19orf81
chromosome 19 open reading frame 81
9024
0.12
chr14_105330590_105330952 0.50 CEP170B
centrosomal protein 170B
846
0.6
chr17_48423822_48424723 0.50 XYLT2
xylosyltransferase II
776
0.5
chr1_27286242_27286878 0.50 C1orf172
chromosome 1 open reading frame 172
337
0.84
chr12_124907458_124907665 0.50 NCOR2
nuclear receptor corepressor 2
34191
0.22
chr10_5637782_5638011 0.50 ENSG00000240577
.
35530
0.13
chr4_180979181_180979679 0.49 NA
NA
> 106
NA
chr6_5999099_5999932 0.48 NRN1
neuritin 1
7685
0.26
chr6_169067989_169068140 0.48 SMOC2
SPARC related modular calcium binding 2
14300
0.31
chr12_81471441_81472090 0.48 ACSS3
acyl-CoA synthetase short-chain family member 3
71
0.98
chr2_87842220_87842459 0.48 RP11-1399P15.1

64786
0.13
chr16_4986136_4987107 0.48 PPL
periplakin
444
0.78
chr9_133302665_133302816 0.47 HMCN2
hemicentin 2
2929
0.21
chr10_35102956_35103650 0.47 PARD3
par-3 family cell polarity regulator
946
0.5
chr15_74472398_74472549 0.47 RP11-665J16.1

906
0.44
chr10_134659120_134659271 0.47 TTC40
tetratricopeptide repeat domain 40
10338
0.24
chr1_204168084_204168306 0.46 KISS1
KiSS-1 metastasis-suppressor
2581
0.22
chr4_87769790_87770024 0.46 SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
509
0.85
chr13_50985558_50985709 0.45 ENSG00000221198
.
48260
0.19
chr3_52016673_52017699 0.45 ABHD14B
abhydrolase domain containing 14B
239
0.49
chr15_45455270_45455421 0.45 RP11-519G16.2

7197
0.1
chr21_47394855_47395106 0.45 COL6A1
collagen, type VI, alpha 1
6671
0.21
chr5_16934329_16934610 0.44 MYO10
myosin X
1578
0.42
chr3_138635529_138635680 0.44 FOXL2
forkhead box L2
30378
0.16
chr1_242688162_242688638 0.44 PLD5
phospholipase D family, member 5
402
0.92
chr2_46165643_46166035 0.44 PRKCE
protein kinase C, epsilon
62202
0.14
chr5_172754207_172754714 0.44 STC2
stanniocalcin 2
596
0.75
chr17_9018882_9019405 0.44 NTN1
netrin 1
47109
0.15
chr1_151483990_151484782 0.44 CGN
cingulin
513
0.66
chr5_3600266_3600509 0.43 CTD-2012M11.3

85
0.98
chr1_201436884_201437966 0.43 PHLDA3
pleckstrin homology-like domain, family A, member 3
887
0.55
chr9_100849786_100850488 0.43 TRIM14
tripartite motif containing 14
4706
0.2
chr22_19754354_19754802 0.42 TBX1
T-box 1
10352
0.18
chr19_19216646_19216851 0.42 TMEM161A
transmembrane protein 161A
26462
0.11
chr9_131013035_131013541 0.42 ENSG00000264823
.
5979
0.09
chr2_129365727_129365883 0.42 ENSG00000238379
.
163033
0.04
chr20_39970036_39970187 0.42 LPIN3
lipin 3
551
0.77
chr16_1132922_1133073 0.42 SSTR5
somatostatin receptor 5
4128
0.16
chr17_37856067_37857084 0.42 ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
242
0.86
chr5_17216444_17217195 0.41 AC091878.1

337
0.76
chr2_27717607_27718081 0.41 FNDC4
fibronectin type III domain containing 4
268
0.82
chr7_100464814_100466140 0.41 TRIP6
thyroid hormone receptor interactor 6
717
0.47
chr22_18506538_18507254 0.41 MICAL3
microtubule associated monooxygenase, calponin and LIM domain containing 3
429
0.79
chr12_125002064_125002257 0.41 NCOR2
nuclear receptor corepressor 2
680
0.82
chr2_133173748_133173945 0.40 GPR39
G protein-coupled receptor 39
301
0.92
chr16_4422135_4423224 0.40 VASN
vasorin
830
0.49
chr10_48354710_48355282 0.40 ZNF488
zinc finger protein 488
28
0.97
chr19_41699238_41699877 0.40 CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
405
0.76
chr3_48631663_48631917 0.40 COL7A1
collagen, type VII, alpha 1
803
0.43
chr9_130330127_130331202 0.40 FAM129B
family with sequence similarity 129, member B
703
0.67
chr5_174871055_174871780 0.40 DRD1
dopamine receptor D1
206
0.95
chr1_158969255_158969538 0.39 IFI16
interferon, gamma-inducible protein 16
362
0.89
chr17_25879596_25879747 0.39 KSR1
kinase suppressor of ras 1
30276
0.17
chr2_133427269_133427458 0.39 LYPD1
LY6/PLAUR domain containing 1
415
0.87
chr15_40631412_40631563 0.39 C15orf52
chromosome 15 open reading frame 52
756
0.41
chr1_11851036_11851187 0.39 C1orf167
chromosome 1 open reading frame 167
11237
0.1
chr6_56820874_56821079 0.39 BEND6
BEN domain containing 6
806
0.54
chrX_73639854_73640301 0.39 SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
1008
0.55
chr18_61149029_61149180 0.38 RP11-635N19.3

3730
0.21
chr17_39656686_39656897 0.37 AC019349.5

444
0.64
chr2_158113918_158114875 0.37 GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
286
0.93
chr17_21360959_21361110 0.37 KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
52586
0.13
chr17_70587270_70588900 0.37 ENSG00000200783
.
72206
0.12
chr3_50176033_50176184 0.37 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
16370
0.12
chr11_45943886_45945188 0.37 GYLTL1B
glycosyltransferase-like 1B
208
0.9
chr21_47401799_47402727 0.37 COL6A1
collagen, type VI, alpha 1
612
0.75
chr7_44529962_44530754 0.37 NUDCD3
NudC domain containing 3
121
0.96
chr22_29705272_29705553 0.37 GAS2L1
growth arrest-specific 2 like 1
2364
0.17
chr18_19751318_19751469 0.36 GATA6
GATA binding protein 6
499
0.73
chr2_112165488_112165639 0.36 ENSG00000266139
.
86895
0.1
chr17_41656365_41656516 0.36 ETV4
ets variant 4
548
0.74
chr7_42277779_42278105 0.36 GLI3
GLI family zinc finger 3
1284
0.64
chr17_80196270_80197118 0.36 SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
1648
0.23
chr3_159505128_159505279 0.36 IQCJ-SCHIP1-AS1
IQCJ-SCHIP1 readthrough antisense RNA 1
18802
0.15
chr16_2517636_2518674 0.36 RP11-715J22.2

59
0.92
chr8_144682749_144682900 0.36 EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
1113
0.23
chr19_55996251_55997143 0.36 NAT14
N-acetyltransferase 14 (GCN5-related, putative)
96
0.92
chr10_119301594_119301816 0.35 EMX2OS
EMX2 opposite strand/antisense RNA
125
0.68
chr1_156084579_156085364 0.35 LMNA
lamin A/C
458
0.7
chr9_84303354_84304234 0.35 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
198
0.96
chr1_934275_935357 0.35 HES4
hes family bHLH transcription factor 4
545
0.57
chr7_552435_552586 0.35 PDGFA
platelet-derived growth factor alpha polypeptide
5635
0.22
chr6_46702576_46703631 0.35 PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
24
0.97
chr14_105434639_105435137 0.35 AHNAK2
AHNAK nucleoprotein 2
9806
0.16
chr17_38473146_38473297 0.35 RARA
retinoic acid receptor, alpha
1312
0.32
chr20_62328622_62328873 0.35 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
726
0.45
chr4_7023632_7023916 0.35 TADA2B
transcriptional adaptor 2B
19852
0.09
chrX_37545083_37545690 0.35 XK
X-linked Kx blood group (McLeod syndrome)
374
0.91
chr14_96670852_96671050 0.35 BDKRB2
bradykinin receptor B2
65
0.72
chr20_61468182_61468333 0.35 COL9A3
collagen, type IX, alpha 3
19094
0.11
chr10_126812393_126812551 0.35 CTBP2
C-terminal binding protein 2
34813
0.2
chr11_131780761_131781452 0.34 NTM
neurotrimin
209
0.95
chr8_28209037_28209188 0.34 ZNF395
zinc finger protein 395
29
0.97
chr19_56631113_56632184 0.34 ZNF787
zinc finger protein 787
971
0.43
chr1_228337001_228337152 0.34 GJC2
gap junction protein, gamma 2, 47kDa
477
0.67
chr1_159061252_159061624 0.34 AIM2
absent in melanoma 2
14747
0.17
chr2_183731816_183732221 0.34 FRZB
frizzled-related protein
128
0.96
chr6_116772620_116772771 0.34 ENSG00000265516
.
6290
0.14
chr4_55143230_55143451 0.34 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
33598
0.22
chr11_94473290_94474384 0.34 RP11-867G2.8

316
0.92
chr2_219472134_219472377 0.34 PLCD4
phospholipase C, delta 4
233
0.86
chr21_33784461_33785454 0.34 EVA1C
eva-1 homolog C (C. elegans)
36
0.97
chr17_38255735_38256962 0.34 NR1D1
nuclear receptor subfamily 1, group D, member 1
630
0.6
chr19_49238400_49238597 0.34 RASIP1
Ras interacting protein 1
3777
0.1
chr1_228135806_228136352 0.34 WNT9A
wingless-type MMTV integration site family, member 9A
480
0.79
chr14_105435453_105435767 0.34 AHNAK2
AHNAK nucleoprotein 2
9084
0.16
chr7_70049486_70049637 0.34 AUTS2
autism susceptibility candidate 2
144564
0.05
chr2_131010330_131010897 0.33 TUBA3E
tubulin, alpha 3e
54579
0.08
chr6_1624554_1625514 0.33 FOXC1
forkhead box C1
14353
0.29
chr10_106034925_106035119 0.33 GSTO2
glutathione S-transferase omega 2
98
0.95
chr6_1311351_1312220 0.33 FOXQ1
forkhead box Q1
890
0.69
chr12_123429278_123429575 0.33 ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
204
0.92
chr5_134366245_134366951 0.33 PITX1
paired-like homeodomain 1
2227
0.27
chr16_14396121_14396821 0.33 ENSG00000207639
.
1353
0.42
chr14_38052851_38053204 0.33 FOXA1
forkhead box A1
11212
0.23
chr19_37743129_37743340 0.33 ZNF383
zinc finger protein 383
24782
0.13
chr20_62167761_62168265 0.33 PTK6
protein tyrosine kinase 6
682
0.51
chr18_74843262_74844680 0.33 MBP
myelin basic protein
331
0.94
chr3_170407376_170407527 0.33 RP11-373E16.3

33100
0.21
chr4_113626760_113627887 0.33 ENSG00000202536
.
49750
0.09
chr18_31802356_31802659 0.33 NOL4
nucleolar protein 4
225
0.71
chr7_155006231_155006400 0.32 AC099552.4
Uncharacterized protein
16169
0.2
chr9_111313924_111314166 0.32 ENSG00000222512
.
192836
0.03
chr1_62784952_62785183 0.32 KANK4
KN motif and ankyrin repeat domains 4
18
0.98
chr17_70117213_70117669 0.32 SOX9
SRY (sex determining region Y)-box 9
280
0.95
chr8_144656729_144657016 0.32 RP11-661A12.9

1212
0.19
chr9_72658914_72659269 0.32 MAMDC2
MAM domain containing 2
594
0.81
chr20_17207159_17207414 0.32 PCSK2
proprotein convertase subtilisin/kexin type 2
350
0.89
chr6_166075279_166075470 0.32 PDE10A
phosphodiesterase 10A
183
0.97
chr10_57388051_57388558 0.32 PCDH15
protocadherin-related 15
602
0.76
chr6_147828410_147828574 0.32 SAMD5
sterile alpha motif domain containing 5
1571
0.57
chr20_9487123_9487357 0.32 LAMP5
lysosomal-associated membrane protein family, member 5
7765
0.23
chr5_68710635_68711790 0.32 MARVELD2
MARVEL domain containing 2
3
0.97
chr11_119598721_119599273 0.32 PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
266
0.88
chr22_46981461_46981612 0.32 GRAMD4
GRAM domain containing 4
8510
0.22
chr2_227662938_227664059 0.32 IRS1
insulin receptor substrate 1
977
0.58
chr9_21974540_21975658 0.32 CDKN2A
cyclin-dependent kinase inhibitor 2A
2
0.97
chr21_44795271_44795422 0.31 SIK1
salt-inducible kinase 1
51662
0.16
chr19_3343996_3344371 0.31 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
15378
0.17
chr2_241860515_241860848 0.31 AC104809.3
Protein LOC728763
1305
0.38
chr14_25518330_25518565 0.31 STXBP6
syntaxin binding protein 6 (amisyn)
241
0.96
chr3_48468926_48469077 0.31 PLXNB1
plexin B1
1871
0.18
chr19_4472643_4473577 0.31 HDGFRP2
Hepatoma-derived growth factor-related protein 2
807
0.39
chr17_81067326_81067613 0.31 METRNL
meteorin, glial cell differentiation regulator-like
15475
0.24
chr8_27530559_27530710 0.31 ENSG00000222862
.
6715
0.16
chr10_95229341_95229492 0.31 MYOF
myoferlin
12535
0.19
chr17_74525960_74526111 0.31 CYGB
cytoglobin
2112
0.15
chr15_67400456_67400607 0.31 SMAD3
SMAD family member 3
9514
0.25
chr9_140093629_140094566 0.31 TPRN
taperin
460
0.53
chr19_41120135_41120880 0.30 LTBP4
latent transforming growth factor beta binding protein 4
685
0.6
chr16_1922185_1922470 0.30 MEIOB
meiosis specific with OB domains
148
0.88
chr1_31380173_31380807 0.30 SDC3
syndecan 3
1118
0.44
chr16_58767280_58768341 0.30 GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial
420
0.82
chr2_74668159_74668310 0.30 RTKN
rhotekin
476
0.58
chr11_7694729_7695430 0.30 CYB5R2
cytochrome b5 reductase 2
78
0.97
chr12_126468546_126468697 0.30 TMEM132B
transmembrane protein 132B
361579
0.01
chr1_66258526_66259233 0.30 PDE4B
phosphodiesterase 4B, cAMP-specific
15
0.99
chr1_95286002_95286302 0.30 SLC44A3
solute carrier family 44, member 3
25
0.98
chr5_6767017_6767234 0.30 PAPD7
PAP associated domain containing 7
52380
0.15
chr10_73769586_73770005 0.30 CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
45672
0.15
chr22_47550419_47550650 0.30 ENSG00000221672
.
306731
0.01
chr2_1594989_1595282 0.30 AC144450.1

28750
0.22
chr8_49292805_49293034 0.30 ENSG00000252710
.
72329
0.13
chr6_10419619_10419946 0.30 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
89
0.97
chr17_7942417_7942568 0.30 ALOX15B
arachidonate 15-lipoxygenase, type B
18
0.95
chr1_151283798_151284073 0.29 ENSG00000265753
.
10496
0.09
chr12_57522507_57523183 0.29 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
38
0.64
chr20_49465299_49465721 0.29 ENSG00000265062
.
11935
0.18
chr17_79799803_79799954 0.29 RP11-498C9.2

1163
0.22
chr13_37005266_37006411 0.29 CCNA1
cyclin A1
129
0.97
chr3_188390324_188390475 0.29 ENSG00000207651
.
16170
0.22
chr20_50178684_50179923 0.29 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
67
0.99

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0021542 dentate gyrus development(GO:0021542)
0.2 0.7 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.2 0.5 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2 0.7 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.4 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.3 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.1 0.5 GO:0072070 loop of Henle development(GO:0072070)
0.1 0.2 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.3 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.1 0.4 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 0.3 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.3 GO:0009648 photoperiodism(GO:0009648)
0.1 0.5 GO:0090103 cochlea morphogenesis(GO:0090103)
0.1 0.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.3 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.1 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.3 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 0.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.1 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.2 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.1 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.2 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.1 0.4 GO:0015871 choline transport(GO:0015871)
0.1 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.2 GO:0060013 righting reflex(GO:0060013)
0.1 0.2 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.1 0.4 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1 0.1 GO:0070141 response to UV-A(GO:0070141)
0.1 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:0051956 negative regulation of amino acid transport(GO:0051956)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0031223 auditory behavior(GO:0031223)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.4 GO:0009651 response to salt stress(GO:0009651)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.8 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.2 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.4 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0036473 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0 0.1 GO:0090102 cochlea development(GO:0090102)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 0.2 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.0 GO:1902667 regulation of axon extension involved in axon guidance(GO:0048841) regulation of axon guidance(GO:1902667)
0.0 0.4 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.1 GO:0071364 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.0 GO:0048318 axial mesoderm development(GO:0048318) axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.2 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 1.1 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0043096 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0007616 long-term memory(GO:0007616)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.0 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.0 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0048640 negative regulation of developmental growth(GO:0048640)
0.0 0.4 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.4 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.2 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0007530 sex determination(GO:0007530)
0.0 0.1 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 0.1 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.0 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.0 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0 0.1 GO:1900006 positive regulation of dendrite morphogenesis(GO:0050775) positive regulation of dendrite development(GO:1900006)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0007569 cell aging(GO:0007569)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.0 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.1 GO:0006760 folic acid-containing compound metabolic process(GO:0006760)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0032925 regulation of activin receptor signaling pathway(GO:0032925)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0048265 response to pain(GO:0048265)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0060177 regulation of angiotensin metabolic process(GO:0060177)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.4 GO:0071437 invadopodium(GO:0071437)
0.1 0.3 GO:0042825 TAP complex(GO:0042825)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0005605 basal lamina(GO:0005605)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 3.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0030286 dynein complex(GO:0030286)
0.0 0.0 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.4 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.8 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.5 GO:0001601 peptide YY receptor activity(GO:0001601)
0.2 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0046980 tapasin binding(GO:0046980)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.6 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.4 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.1 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.2 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.1 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.2 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0031420 alkali metal ion binding(GO:0031420)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0019798 procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0009975 cyclase activity(GO:0009975)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.0 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.7 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.1 REACTOME OPSINS Genes involved in Opsins
0.1 0.1 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 0.3 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.1 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.0 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 1.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines