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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for TFCP2

Z-value: 1.30

Motif logo

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Transcription factors associated with TFCP2

Gene Symbol Gene ID Gene Info
TFCP2
ENSG00000135457.5 transcription factor CP2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_51565743_51565945TFCP27320.5576650.771.6e-02Click!
chr12_51567069_51567255TFCP22360.890721-0.324.0e-01Click!
chr12_51566615_51566911TFCP2680.958729-0.274.8e-01Click!
chr12_51563573_51563724TFCP229280.174409-0.225.7e-01Click!
chr12_51566002_51566548TFCP23010.8502010.215.8e-01Click!

Activity of the TFCP2 motif across conditions

Conditions sorted by the z-value of the TFCP2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_217929529_217929680 0.52 ENSG00000251849
 .
 111617
 0.06
chr15_48936207_48936433 0.48 FBN1
 fibrillin 1
 1598
 0.51
chr3_106954545_106954751 0.43 ENSG00000220989
 .
 129381
 0.06
chr4_16899159_16899373 0.43 LDB2
 LIM domain binding 2
 919
 0.75
chr22_40672488_40672756 0.42 TNRC6B
 trinucleotide repeat containing 6B
 11615
 0.23
chr18_56245541_56245920 0.39 RP11-126O1.2
21428
 0.14
chrX_34673275_34673426 0.36 TMEM47
 transmembrane protein 47
 2055
 0.5
chr4_55096991_55097208 0.36 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
 610
 0.82
chr15_96870719_96871095 0.34 NR2F2-AS1
 NR2F2 antisense RNA 1
 317
 0.84
chr7_15725092_15725754 0.33 MEOX2
 mesenchyme homeobox 2
 1014
 0.63
chr17_67137803_67138011 0.33 ABCA6
 ATP-binding cassette, sub-family A (ABC1), member 6
 108
 0.97
chr7_19152487_19152712 0.33 AC003986.6
502
 0.75
chr9_18297085_18297314 0.32 ADAMTSL1
 ADAMTS-like 1
 176693
 0.03
chr1_26348142_26348482 0.32 EXTL1
 exostosin-like glycosyltransferase 1
 41
 0.95
chr15_70994869_70995020 0.31 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 297
 0.94
chr3_52737763_52738047 0.30 GLT8D1
 glycosyltransferase 8 domain containing 1
 270
 0.75
chr11_119211431_119211655 0.30 C1QTNF5
 C1q and tumor necrosis factor related protein 5
 50
 0.94
chr14_55707492_55707643 0.30 FBXO34
 F-box protein 34
 30454
 0.18
chr5_158488269_158488591 0.30 EBF1
 early B-cell factor 1
 38271
 0.17
chr6_3389887_3390179 0.29 SLC22A23
 solute carrier family 22, member 23
 49619
 0.15
chr10_101767094_101767245 0.29 DNMBP
 dynamin binding protein
 2507
 0.28
chr1_114522141_114522332 0.29 OLFML3
 olfactomedin-like 3
 171
 0.95
chr5_129241672_129241829 0.28 CTC-575N7.1
140
 0.95
chr15_48936731_48936882 0.28 FBN1
 fibrillin 1
 1112
 0.63
chrX_34671991_34672311 0.28 TMEM47
 transmembrane protein 47
 3254
 0.41
chr8_13355358_13355509 0.28 DLC1
 deleted in liver cancer 1
 1317
 0.52
chr3_29321285_29321499 0.27 RBMS3
 RNA binding motif, single stranded interacting protein 3
 1081
 0.59
chr12_76422291_76422442 0.27 RP11-290L1.3
1908
 0.31
chr13_37492943_37493377 0.27 SMAD9
 SMAD family member 9
 1215
 0.52
chr19_55972195_55972559 0.27 ISOC2
 isochorismatase domain containing 2
 559
 0.55
chr17_15522812_15523031 0.27 CDRT1
 CMT1A duplicated region transcript 1
 95
 0.95
chr12_48395504_48395664 0.26 COL2A1
 collagen, type II, alpha 1
 2520
 0.21
chr2_102089965_102090218 0.26 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 646
 0.8
chr11_131780761_131781452 0.26 NTM
 neurotrimin
 209
 0.95
chr13_76054815_76055003 0.26 TBC1D4
 TBC1 domain family, member 4
 1341
 0.51
chr10_3666636_3666787 0.26 RP11-184A2.3
126548
 0.06
chr2_66667990_66668184 0.26 MEIS1
 Meis homeobox 1
 277
 0.68
chr16_11445129_11445310 0.26 RP11-485G7.6
2041
 0.16
chr2_216297601_216297993 0.26 FN1
 fibronectin 1
 2993
 0.27
chr11_118435857_118436109 0.25 IFT46
 intraflagellar transport 46 homolog (Chlamydomonas)
 378
 0.76
chr3_119180886_119181037 0.25 TMEM39A
 transmembrane protein 39A
 1502
 0.36
chr5_78760442_78760593 0.25 HOMER1
 homer homolog 1 (Drosophila)
 48100
 0.16
chr7_46895478_46895629 0.25 AC011294.3
 Uncharacterized protein
 158833
 0.04
chr14_61492437_61492630 0.25 SLC38A6
 solute carrier family 38, member 6
 17335
 0.21
chr12_119617823_119618008 0.25 HSPB8
 heat shock 22kDa protein 8
 520
 0.73
chr1_212734986_212735137 0.25 ATF3
 activating transcription factor 3
 3615
 0.24
chr12_50614114_50614771 0.25 RP3-405J10.4
1055
 0.35
chr15_60684258_60684446 0.25 ANXA2
 annexin A2
 856
 0.71
chr16_11085461_11085694 0.25 CLEC16A
 C-type lectin domain family 16, member A
 47139
 0.1
chr1_190447721_190448034 0.24 BRINP3
 bone morphogenetic protein/retinoic acid inducible neural-specific 3
 1118
 0.69
chr5_137390877_137391028 0.24 FAM13B
 family with sequence similarity 13, member B
 3302
 0.16
chr7_116035241_116035541 0.24 ENSG00000252672
 .
 37877
 0.14
chr15_96883311_96883827 0.24 ENSG00000222651
 .
 7079
 0.16
chr21_46629242_46629401 0.24 ADARB1
 adenosine deaminase, RNA-specific, B1
 37764
 0.14
chr8_72460104_72460292 0.24 RP11-1102P16.1
 Uncharacterized protein
 306
 0.94
chr5_14448576_14448727 0.24 TRIO
 trio Rho guanine nucleotide exchange factor
 39906
 0.21
chr13_36049575_36050388 0.24 MAB21L1
 mab-21-like 1 (C. elegans)
 851
 0.43
chr1_196622943_196623164 0.24 CFH
 complement factor H
 1867
 0.41
chr15_34786644_34787173 0.24 ENSG00000221065
 .
 33664
 0.14
chr20_53092813_53093232 0.24 DOK5
 docking protein 5
 765
 0.8
chr6_85896028_85896266 0.24 NT5E
 5'-nucleotidase, ecto (CD73)
 263662
 0.02
chr19_11563038_11563189 0.24 ENSG00000238349
 .
 13116
 0.08
chr14_55117285_55117487 0.24 SAMD4A
 sterile alpha motif domain containing 4A
 82749
 0.09
chr6_27516181_27516437 0.24 ENSG00000206671
 .
 47882
 0.13
chr11_125929704_125929855 0.23 CDON
 cell adhesion associated, oncogene regulated
 2927
 0.28
chr5_79421582_79421788 0.23 CTC-458I2.2
2499
 0.32
chr1_164534283_164534434 0.23 PBX1
 pre-B-cell leukemia homeobox 1
 2316
 0.4
chr17_32583150_32583439 0.23 AC005549.3
 Uncharacterized protein
 988
 0.32
chr22_45898941_45899504 0.23 FBLN1
 fibulin 1
 296
 0.92
chr5_82770538_82771175 0.23 VCAN
 versican
 3112
 0.37
chr1_39733773_39734441 0.23 MACF1
 microtubule-actin crosslinking factor 1
 92
 0.97
chr12_72665965_72666270 0.23 ENSG00000236333
 .
 189
 0.69
chr10_128994049_128994367 0.23 FAM196A
 family with sequence similarity 196, member A
 214
 0.97
chr18_56244732_56244930 0.23 RP11-126O1.2
20529
 0.14
chr12_105727681_105727958 0.23 C12orf75
 chromosome 12 open reading frame 75
 3173
 0.24
chr5_35129380_35129531 0.23 PRLR
 prolactin receptor
 991
 0.64
chr4_67431234_67431385 0.23 ENSG00000221563
 .
 288767
 0.01
chr14_50089328_50089479 0.23 RP11-649E7.5
795
 0.35
chr18_55470424_55470575 0.23 ATP8B1
 ATPase, aminophospholipid transporter, class I, type 8B, member 1
 172
 0.96
chr1_23066485_23066803 0.23 ENSG00000216157
 .
 8760
 0.17
chr2_119532290_119532494 0.22 EN1
 engrailed homeobox 1
 72862
 0.12
chr4_26023554_26023967 0.22 SMIM20
 small integral membrane protein 20
 107829
 0.07
chr1_98510769_98511355 0.22 ENSG00000225206
 .
 155
 0.98
chr7_128471351_128471889 0.22 FLNC
 filamin C, gamma
 1140
 0.39
chr1_240501387_240501653 0.22 ENSG00000252317
 .
 3165
 0.32
chr4_19691164_19691362 0.22 ENSG00000251816
 .
 507784
 0.0
chr12_110705323_110705474 0.22 ATP2A2
 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
 13163
 0.23
chr11_133903795_133903999 0.22 JAM3
 junctional adhesion molecule 3
 34923
 0.17
chr10_95518290_95518441 0.22 LGI1
 leucine-rich, glioma inactivated 1
 687
 0.76
chr9_110811607_110811808 0.22 ENSG00000222459
 .
 130448
 0.05
chr17_47210248_47210565 0.22 B4GALNT2
 beta-1,4-N-acetyl-galactosaminyl transferase 2
 77
 0.97
chr12_40013401_40013886 0.22 ABCD2
 ATP-binding cassette, sub-family D (ALD), member 2
 90
 0.98
chr18_7460861_7461013 0.22 PTPRM
 protein tyrosine phosphatase, receptor type, M
 105843
 0.07
chr1_86045223_86045434 0.22 CYR61
 cysteine-rich, angiogenic inducer, 61
 1116
 0.4
chr15_102156310_102156522 0.22 ENSG00000252614
 .
 32099
 0.15
chrX_45626308_45626459 0.21 ENSG00000207725
 .
 19853
 0.22
chr6_37663843_37664045 0.21 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 643
 0.8
chr12_125395024_125395175 0.21 UBC
 ubiquitin C
 3521
 0.19
chr1_87670295_87670446 0.21 ENSG00000221222
 .
 53389
 0.16
chrX_64255707_64255858 0.21 ZC4H2
 zinc finger, C4H2 domain containing
 1189
 0.66
chr10_62174775_62175056 0.21 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 25427
 0.28
chr1_215130950_215131319 0.21 KCNK2
 potassium channel, subfamily K, member 2
 48064
 0.2
chr3_105555914_105556177 0.21 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 31842
 0.26
chr10_92680601_92680752 0.21 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
 357
 0.84
chr1_78474827_78475270 0.21 DNAJB4
 DnaJ (Hsp40) homolog, subfamily B, member 4
 4510
 0.17
chr3_187870695_187870846 0.21 LPP
 LIM domain containing preferred translocation partner in lipoma
 302
 0.84
chr2_75792595_75792746 0.21 EVA1A
 eva-1 homolog A (C. elegans)
 4178
 0.2
chr17_772969_773237 0.21 NXN
 nucleoredoxin
 5752
 0.17
chr1_117028958_117029109 0.21 ENSG00000200547
 .
 33875
 0.13
chr16_86549558_86549709 0.21 FOXF1
 forkhead box F1
 5500
 0.21
chr14_77294740_77294891 0.21 C14orf166B
 chromosome 14 open reading frame 166B
 140
 0.96
chr12_78684646_78684797 0.21 NAV3
 neuron navigator 3
 91865
 0.1
chr10_31410381_31410532 0.21 ENSG00000263578
 .
 55480
 0.15
chr14_42077252_42077403 0.21 LRFN5
 leucine rich repeat and fibronectin type III domain containing 5
 291
 0.93
chr6_11230027_11230357 0.21 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 2699
 0.33
chr3_114378409_114378560 0.21 ZBTB20
 zinc finger and BTB domain containing 20
 34692
 0.22
chr19_16493261_16493427 0.20 ENSG00000243745
 .
 16426
 0.13
chr20_53239107_53239289 0.20 DOK5
 docking protein 5
 146941
 0.05
chr18_65662332_65662579 0.20 DSEL
 dermatan sulfate epimerase-like
 478238
 0.01
chr15_56206090_56206310 0.20 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
 1652
 0.45
chr4_146052413_146052564 0.20 ENSG00000238713
 .
 18313
 0.17
chrX_34673509_34673660 0.20 TMEM47
 transmembrane protein 47
 1821
 0.53
chr11_27603199_27603543 0.20 BDNF-AS
 BDNF antisense RNA
 58065
 0.11
chr6_151392043_151392194 0.20 RP1-292B18.3
14925
 0.18
chr19_30941733_30942003 0.20 ZNF536
 zinc finger protein 536
 78549
 0.12
chr4_177712658_177713139 0.20 VEGFC
 vascular endothelial growth factor C
 983
 0.71
chr6_35286420_35286751 0.20 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 9070
 0.18
chrX_51636554_51637686 0.20 MAGED1
 melanoma antigen family D, 1
 385
 0.89
chr4_41615256_41615763 0.20 LIMCH1
 LIM and calponin homology domains 1
 16
 0.99
chr5_92937754_92938000 0.20 ENSG00000237187
 .
 16523
 0.18
chr4_39527980_39528193 0.20 UGDH
 UDP-glucose 6-dehydrogenase
 91
 0.95
chr11_76380846_76381073 0.20 LRRC32
 leucine rich repeat containing 32
 85
 0.97
chr1_60204181_60204332 0.20 ENSG00000266150
 .
 5288
 0.28
chr19_36736141_36736420 0.20 ZNF565
 zinc finger protein 565
 879
 0.5
chr6_169652381_169652976 0.20 THBS2
 thrombospondin 2
 432
 0.89
chr15_37179413_37179956 0.20 ENSG00000212511
 .
 34843
 0.22
chr9_102130860_102131451 0.20 ENSG00000222337
 .
 84851
 0.09
chr8_129852489_129852640 0.20 ENSG00000221351
 .
 20524
 0.29
chr9_119449393_119449768 0.20 TRIM32
 tripartite motif containing 32
 1
 0.54
chr8_96734481_96734632 0.20 ENSG00000223297
 .
 43413
 0.2
chr17_57449049_57449286 0.19 ENSG00000263857
 .
 5723
 0.19
chrX_135771582_135771733 0.19 CD40LG
 CD40 ligand
 41271
 0.12
chr9_1917275_1917426 0.19 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 97992
 0.08
chr9_82301184_82301335 0.19 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 18439
 0.31
chr5_33442964_33443296 0.19 TARS
 threonyl-tRNA synthetase
 1643
 0.41
chr22_31092194_31092345 0.19 OSBP2
 oxysterol binding protein 2
 1393
 0.36
chr10_63422698_63423173 0.19 C10orf107
 chromosome 10 open reading frame 107
 180
 0.96
chr7_107886376_107886580 0.19 NRCAM
 neuronal cell adhesion molecule
 2794
 0.37
chr7_18127374_18127525 0.19 HDAC9
 histone deacetylase 9
 877
 0.66
chr13_53173841_53174134 0.19 HNRNPA1L2
 heterogeneous nuclear ribonucleoprotein A1-like 2
 17618
 0.22
chr10_118547842_118547993 0.19 HSPA12A
 heat shock 70kDa protein 12A
 45832
 0.13
chr15_59622460_59622641 0.19 ENSG00000199512
 .
 11066
 0.14
chr4_15471787_15471987 0.19 CC2D2A
 coiled-coil and C2 domain containing 2A
 250
 0.93
chr10_375832_375983 0.19 DIP2C
 DIP2 disco-interacting protein 2 homolog C (Drosophila)
 441
 0.85
chr10_32153572_32153723 0.19 ARHGAP12
 Rho GTPase activating protein 12
 10539
 0.28
chr6_113994297_113994452 0.19 ENSG00000221559
 .
 31661
 0.2
chr11_71750979_71751491 0.19 NUMA1
 nuclear mitotic apparatus protein 1
 364
 0.76
chr13_36491458_36491923 0.19 DCLK1
 doublecortin-like kinase 1
 61911
 0.15
chr11_19092979_19093139 0.19 MRGPRX2
 MAS-related GPR, member X2
 10831
 0.22
chr17_48797815_48798020 0.19 LUC7L3
 LUC7-like 3 (S. cerevisiae)
 909
 0.47
chr16_79605167_79605329 0.19 MAF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
 28551
 0.25
chr6_86159077_86159694 0.19 NT5E
 5'-nucleotidase, ecto (CD73)
 424
 0.9
chr9_179160_179373 0.19 CBWD1
 COBW domain containing 1
 194
 0.94
chrX_54947220_54948504 0.19 TRO
 trophinin
 41
 0.97
chr20_42087598_42088018 0.19 SRSF6
 serine/arginine-rich splicing factor 6
 1240
 0.39
chr11_79148234_79148400 0.19 TENM4
 teneurin transmembrane protein 4
 3378
 0.27
chr10_4223311_4223462 0.19 ENSG00000207124
 .
 333758
 0.01
chr1_117912075_117912374 0.18 MAN1A2
 mannosidase, alpha, class 1A, member 2
 2153
 0.44
chr4_108539974_108540125 0.18 PAPSS1
 3'-phosphoadenosine 5'-phosphosulfate synthase 1
 101559
 0.08
chr19_14444112_14444508 0.18 CD97
 CD97 molecule
 47658
 0.1
chr12_107352268_107352490 0.18 C12orf23
 chromosome 12 open reading frame 23
 1816
 0.3
chr2_44404368_44404519 0.18 PPM1B
 protein phosphatase, Mg2+/Mn2+ dependent, 1B
 8394
 0.18
chr15_49063488_49063639 0.18 RP11-485O10.2
11824
 0.19
chr2_150505079_150505230 0.18 ENSG00000207270
 .
 37866
 0.18
chr8_54797720_54797871 0.18 RGS20
 regulator of G-protein signaling 20
 4341
 0.21
chr19_14605870_14606060 0.18 GIPC1
 GIPC PDZ domain containing family, member 1
 979
 0.38
chr6_22881696_22881893 0.18 ENSG00000207394
 .
 243521
 0.02
chr2_42159815_42159972 0.18 C2orf91
 chromosome 2 open reading frame 91
 21050
 0.21
chr13_80707220_80707565 0.18 SPRY2
 sprouty homolog 2 (Drosophila)
 206402
 0.03
chr9_91093036_91093232 0.18 NXNL2
 nucleoredoxin-like 2
 56882
 0.14
chr20_3778661_3778819 0.18 CDC25B
 cell division cycle 25B
 1662
 0.25
chr10_33410829_33411028 0.18 ENSG00000263576
 .
 23364
 0.21
chr7_43605854_43606005 0.18 ENSG00000252308
 .
 12558
 0.18
chr3_161633215_161633436 0.18 OTOL1
 otolin 1
 418729
 0.01
chr3_139000860_139001011 0.18 MRPS22
 mitochondrial ribosomal protein S22
 61926
 0.1
chr6_90695271_90695484 0.18 ENSG00000222078
 .
 15848
 0.19
chr6_85836289_85836440 0.18 NT5E
 5'-nucleotidase, ecto (CD73)
 323445
 0.01
chr6_99284839_99284990 0.18 POU3F2
 POU class 3 homeobox 2
 2334
 0.45
chr8_80525611_80525912 0.18 STMN2
 stathmin-like 2
 1791
 0.51
chr13_111862424_111862612 0.18 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
 4882
 0.27
chr7_707964_708478 0.18 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
 23210
 0.18
chr7_94030181_94030408 0.18 COL1A2
 collagen, type I, alpha 2
 6421
 0.29
chr22_40706773_40706982 0.18 ADSL
 adenylosuccinate lyase
 35630
 0.14
chr1_214620651_214620839 0.18 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 17401
 0.26
chr1_156677371_156677522 0.18 CRABP2
 cellular retinoic acid binding protein 2
 1838
 0.18
chr3_183966275_183966684 0.18 ALG3
 ALG3, alpha-1,3- mannosyltransferase
 244
 0.79
chr2_192110869_192111020 0.18 MYO1B
 myosin IB
 65
 0.98
chr4_186064841_186065084 0.18 SLC25A4
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
 567
 0.76
chr7_93925404_93925563 0.18 COL1A2
 collagen, type I, alpha 2
 98390
 0.08
chr1_33645945_33646389 0.18 TRIM62
 tripartite motif containing 62
 1100
 0.55

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.6 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.2 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.4 GO:0001553 luteinization(GO:0001553)
0.1 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0060592 mammary gland formation(GO:0060592) mammary placode formation(GO:0060596)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:2000053 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.6 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.3 GO:0032400 melanosome localization(GO:0032400)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779) regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.0 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:1901890 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0007619 courtship behavior(GO:0007619)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.3 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.1 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.1 GO:0014034 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.0 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.0 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.1 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0002248 wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0032651 regulation of interleukin-1 beta production(GO:0032651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0001527 microfibril(GO:0001527)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.0 GO:0032059 bleb(GO:0032059)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0043176 amine binding(GO:0043176)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4