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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for THRB

Z-value: 0.37

Motif logo

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Transcription factors associated with THRB

Gene Symbol Gene ID Gene Info
ENSG00000151090.13 THRB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
THRBchr3_24101464_241016511055290.065211-0.854.1e-03Click!
THRBchr3_24283504_24283655764930.116760-0.836.0e-03Click!
THRBchr3_24218786_24218937117750.299154-0.826.5e-03Click!
THRBchr3_24263536_24263687565250.162538-0.801.0e-02Click!
THRBchr3_24548896_24549047121980.177837-0.781.3e-02Click!

Activity of the THRB motif across conditions

Conditions sorted by the z-value of the THRB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_118094529_118095128 0.37 AMICA1
adhesion molecule, interacts with CXADR antigen 1
26
0.97
chr14_22963855_22964006 0.33 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
7759
0.1
chr17_73840046_73840332 0.33 UNC13D
unc-13 homolog D (C. elegans)
226
0.84
chr8_128987632_128988045 0.29 ENSG00000221771
.
14959
0.16
chr2_106392629_106392859 0.28 NCK2
NCK adaptor protein 2
30556
0.23
chr17_72749074_72749225 0.28 MIR3615
microRNA 3615
4098
0.11
chr13_105791565_105791981 0.27 DAOA
D-amino acid oxidase activator
326819
0.01
chr13_34184631_34184800 0.25 RFC3
replication factor C (activator 1) 3, 38kDa
207471
0.02
chr18_77283391_77284187 0.25 AC018445.1
Uncharacterized protein
7732
0.29
chr10_114135452_114136486 0.24 ACSL5
acyl-CoA synthetase long-chain family member 5
12
0.98
chr1_241715191_241715459 0.24 KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
16610
0.2
chr1_36786583_36786988 0.23 RP11-268J15.5

2550
0.19
chr11_3858945_3859096 0.23 RHOG
ras homolog family member G
77
0.94
chr15_31623203_31623354 0.21 KLF13
Kruppel-like factor 13
4220
0.35
chr11_73499157_73499522 0.21 MRPL48
mitochondrial ribosomal protein L48
364
0.84
chr1_203277833_203278085 0.21 BTG2
BTG family, member 2
3295
0.22
chr2_10472194_10472345 0.20 HPCAL1
hippocalcin-like 1
28443
0.15
chr14_102281143_102281546 0.20 CTD-2017C7.2

4686
0.17
chrX_11781800_11781951 0.20 MSL3
male-specific lethal 3 homolog (Drosophila)
4128
0.35
chr1_151798177_151798381 0.20 RORC
RAR-related orphan receptor C
288
0.78
chr12_117536177_117536841 0.20 TESC
tescalcin
742
0.76
chr22_30819167_30819485 0.20 RNF215
ring finger protein 215
1566
0.14
chr8_27237778_27238009 0.19 PTK2B
protein tyrosine kinase 2 beta
275
0.93
chr12_26351665_26351816 0.19 SSPN
sarcospan
3134
0.29
chr19_1068246_1068401 0.19 HMHA1
histocompatibility (minor) HA-1
826
0.4
chr8_74657868_74658768 0.19 STAU2
staufen double-stranded RNA binding protein 2
757
0.75
chr3_187803854_187804005 0.19 LPP
LIM domain containing preferred translocation partner in lipoma
67143
0.12
chr12_53719733_53719917 0.19 AAAS
achalasia, adrenocortical insufficiency, alacrimia
1283
0.29
chr17_38490189_38490340 0.19 RARA
retinoic acid receptor, alpha
7376
0.11
chr3_50606285_50606482 0.19 HEMK1
HemK methyltransferase family member 1
200
0.89
chr3_41159090_41159342 0.18 CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
77112
0.12
chr5_148726870_148727055 0.18 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
1897
0.22
chr12_7063274_7063561 0.17 PTPN6
protein tyrosine phosphatase, non-receptor type 6
2879
0.08
chr1_78546388_78546598 0.17 ENSG00000251958
.
8274
0.17
chr9_139267510_139268079 0.17 CARD9
caspase recruitment domain family, member 9
339
0.79
chr8_28601710_28601861 0.16 EXTL3
exostosin-like glycosyltransferase 3
14108
0.17
chr6_42332393_42332544 0.16 ENSG00000221252
.
47666
0.14
chr14_98443402_98443682 0.16 C14orf64
chromosome 14 open reading frame 64
841
0.77
chr9_130823670_130823942 0.16 RP11-379C10.1

4165
0.12
chrX_11768810_11768961 0.16 MSL3
male-specific lethal 3 homolog (Drosophila)
7393
0.31
chr5_74806864_74807381 0.16 COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
332
0.59
chr2_177503220_177503371 0.15 ENSG00000252027
.
26109
0.25
chr14_50365431_50365582 0.15 ENSG00000251929
.
3162
0.16
chrX_40033281_40033432 0.15 BCOR
BCL6 corepressor
3217
0.38
chr7_103577846_103577997 0.15 RELN
reelin
52042
0.18
chr18_52985449_52985614 0.15 TCF4
transcription factor 4
3686
0.35
chr2_30476045_30476196 0.15 LBH
limb bud and heart development
21074
0.22
chr10_120924621_120924984 0.15 SFXN4
sideroflexin 4
252
0.89
chr11_33721707_33721949 0.14 C11orf91
chromosome 11 open reading frame 91
115
0.96
chr19_45354958_45355109 0.14 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
5250
0.12
chr8_11725136_11725560 0.14 CTSB
cathepsin B
146
0.95
chr5_175085682_175085863 0.14 HRH2
histamine receptor H2
739
0.7
chr16_29000534_29000778 0.14 RP11-264B17.5

1443
0.21
chr16_3124352_3124503 0.13 ENSG00000252561
.
4903
0.07
chr19_52642669_52643149 0.13 ZNF616
zinc finger protein 616
90
0.95
chr1_169672728_169672969 0.13 SELL
selectin L
7991
0.2
chr5_111071208_111071359 0.13 STARD4-AS1
STARD4 antisense RNA 1
5197
0.22
chr6_106967766_106968029 0.13 AIM1
absent in melanoma 1
8167
0.21
chr6_143165477_143165628 0.13 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
7368
0.3
chr22_29999046_29999267 0.13 NF2
neurofibromin 2 (merlin)
389
0.83
chr1_218833930_218834081 0.13 ENSG00000212610
.
118764
0.06
chr10_69373029_69373180 0.12 CTNNA3
catenin (cadherin-associated protein), alpha 3
34167
0.23
chr1_21658510_21658661 0.12 ECE1
endothelin converting enzyme 1
13412
0.2
chr22_39843892_39844043 0.12 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
9382
0.15
chr1_117112540_117113022 0.12 CD58
CD58 molecule
867
0.56
chr3_113251981_113252391 0.12 SIDT1
SID1 transmembrane family, member 1
968
0.54
chr6_2999439_2999644 0.12 RP1-90J20.8

173
0.82
chr11_114007906_114008308 0.12 ENSG00000221112
.
50456
0.14
chrX_71321072_71321371 0.12 RGAG4
retrotransposon gag domain containing 4
30457
0.14
chr11_117858339_117858806 0.11 IL10RA
interleukin 10 receptor, alpha
1463
0.41
chr8_93599945_93600096 0.11 ENSG00000221172
.
47543
0.19
chr12_52317139_52317323 0.11 ACVRL1
activin A receptor type II-like 1
7999
0.16
chr13_38170462_38170613 0.11 POSTN
periostin, osteoblast specific factor
2326
0.46
chr10_76727713_76728120 0.11 RP11-77G23.5

56093
0.12
chr20_31251603_31251754 0.11 RP11-410N8.4

62239
0.09
chr20_62367320_62367471 0.11 LIME1
Lck interacting transmembrane adaptor 1
240
0.82
chr15_41316618_41316840 0.11 RP11-540O11.4

32
0.97
chr6_127590111_127590603 0.11 RNF146
ring finger protein 146
2324
0.36
chr1_39457743_39458066 0.11 AKIRIN1
akirin 1
736
0.62
chr1_26316819_26316970 0.11 PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
7218
0.1
chr21_47742400_47742668 0.11 C21orf58
chromosome 21 open reading frame 58
1237
0.31
chr7_92347863_92348047 0.11 ENSG00000206763
.
16827
0.24
chr6_32908448_32908870 0.11 HLA-DMB
major histocompatibility complex, class II, DM beta
120
0.92
chr5_162864043_162864372 0.11 RP11-541P9.3

92
0.81
chr17_3537923_3538154 0.11 SHPK
sedoheptulokinase
1578
0.2
chrX_46694115_46694266 0.10 RP2
retinitis pigmentosa 2 (X-linked recessive)
2185
0.36
chr13_24024495_24024646 0.10 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
16729
0.28
chrX_135848946_135849996 0.10 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
31
0.98
chr19_4067333_4067959 0.10 ZBTB7A
zinc finger and BTB domain containing 7A
703
0.54
chr5_158633601_158634197 0.10 RNF145
ring finger protein 145
743
0.62
chrY_2369174_2369325 0.10 ENSG00000251841
.
283541
0.01
chr17_39137222_39137388 0.10 KRT40
keratin 40
3255
0.1
chr2_62445013_62445164 0.10 B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
2435
0.26
chr1_226069091_226069419 0.10 TMEM63A
transmembrane protein 63A
814
0.51
chr1_225965575_225965972 0.10 SRP9
signal recognition particle 9kDa
136
0.95
chr21_46323297_46323448 0.10 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
7173
0.11
chr13_113622985_113623455 0.10 MCF2L-AS1
MCF2L antisense RNA 1
82
0.79
chr2_242459234_242459385 0.10 STK25
serine/threonine kinase 25
10164
0.13
chrX_2419173_2419324 0.10 DHRSX
dehydrogenase/reductase (SDR family) X-linked
229
0.51
chr1_111682881_111683246 0.09 CEPT1
choline/ethanolamine phosphotransferase 1
215
0.5
chr17_61497297_61497448 0.09 AC015923.1

5699
0.14
chr8_82018570_82018849 0.09 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
5594
0.32
chr17_66259356_66259507 0.09 ARSG
arylsulfatase G
4108
0.19
chr6_25992069_25992220 0.09 U91328.21

7251
0.09
chr12_64375360_64375627 0.09 SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
812
0.7
chr14_78227118_78227433 0.09 C14orf178
chromosome 14 open reading frame 178
42
0.71
chr1_1004234_1004415 0.09 RNF223
ring finger protein 223
5363
0.1
chr12_52918032_52918183 0.09 KRT5
keratin 5
3636
0.13
chr4_40201423_40201705 0.09 RHOH
ras homolog family member H
400
0.87
chr9_70851276_70851465 0.09 CBWD3
COBW domain containing 3
5027
0.19
chr17_48474498_48474752 0.09 LRRC59
leucine rich repeat containing 59
240
0.78
chr6_88410118_88410669 0.09 AKIRIN2
akirin 2
1534
0.41
chr10_69829246_69829489 0.09 HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
4527
0.23
chr16_25043620_25043907 0.08 ARHGAP17
Rho GTPase activating protein 17
16776
0.24
chr3_150994287_150994620 0.08 P2RY14
purinergic receptor P2Y, G-protein coupled, 14
1704
0.34
chr20_4982345_4982709 0.08 SLC23A2
solute carrier family 23 (ascorbic acid transporter), member 2
374
0.87
chr2_198363785_198364521 0.08 HSPD1
heat shock 60kDa protein 1 (chaperonin)
406
0.5
chr4_1238249_1238400 0.08 CTBP1
C-terminal binding protein 1
2613
0.2
chr8_144821974_144822220 0.08 FAM83H
family with sequence similarity 83, member H
6126
0.08
chr9_70495582_70495733 0.08 CBWD5
COBW domain containing 5
5411
0.29
chr5_176856544_176856754 0.08 GRK6
G protein-coupled receptor kinase 6
2794
0.13
chr9_184434_184636 0.08 CBWD1
COBW domain containing 1
5463
0.2
chr19_6772910_6773160 0.08 VAV1
vav 1 guanine nucleotide exchange factor
66
0.96
chr11_75062077_75062724 0.08 ARRB1
arrestin, beta 1
349
0.83
chr9_69267993_69268163 0.08 CBWD6
COBW domain containing 6
5485
0.22
chr15_99859278_99859429 0.07 AC022819.2
Uncharacterized protein
475
0.82
chr17_56026245_56026547 0.07 CUEDC1
CUE domain containing 1
6222
0.17
chr1_40847512_40847991 0.07 SMAP2
small ArfGAP2
7431
0.18
chr22_37542366_37542517 0.07 IL2RB
interleukin 2 receptor, beta
3589
0.14
chr6_31796282_31796804 0.07 HSPA1B
heat shock 70kDa protein 1B
815
0.28
chr19_14496223_14496374 0.07 CD97
CD97 molecule
4042
0.17
chr14_106365954_106366105 0.07 ENSG00000227108
.
483
0.28
chr7_150212054_150212338 0.07 GIMAP7
GTPase, IMAP family member 7
278
0.91
chr17_33446349_33446789 0.07 RAD51D
RAD51 paralog D
4
0.88
chr13_103452681_103453379 0.07 BIVM
basic, immunoglobulin-like variable motif containing
1469
0.24
chr10_100227763_100227980 0.07 HPS1
Hermansky-Pudlak syndrome 1
21188
0.19
chr1_226900274_226900494 0.07 ITPKB
inositol-trisphosphate 3-kinase B
24775
0.18
chrX_64195307_64195683 0.07 ZC4H2
zinc finger, C4H2 domain containing
833
0.78
chr15_85524205_85524489 0.07 PDE8A
phosphodiesterase 8A
603
0.74
chr21_46337373_46337524 0.07 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
3250
0.13
chr8_144650355_144651121 0.07 MROH6
maestro heat-like repeat family member 6
286
0.75
chr12_122238096_122238378 0.07 RHOF
ras homolog family member F (in filopodia)
346
0.85
chr7_150940826_150940977 0.07 RP4-548D19.3

3416
0.12
chr1_26872331_26872899 0.07 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
272
0.88
chr6_30312997_30313362 0.07 RPP21
ribonuclease P/MRP 21kDa subunit
233
0.9
chr5_142225814_142225972 0.07 ARHGAP26-AS1
ARHGAP26 antisense RNA 1
22582
0.24
chr6_12957382_12958434 0.06 PHACTR1
phosphatase and actin regulator 1
306
0.95
chr13_22057996_22058198 0.06 ZDHHC20
zinc finger, DHHC-type containing 20
24588
0.18
chr13_20693229_20693593 0.06 GJA3
gap junction protein, alpha 3, 46kDa
41777
0.15
chr20_30358146_30358468 0.06 TPX2
TPX2, microtubule-associated
31233
0.11
chr11_66059397_66059767 0.06 TMEM151A
transmembrane protein 151A
241
0.77
chr1_20834118_20834607 0.06 MUL1
mitochondrial E3 ubiquitin protein ligase 1
292
0.9
chr1_113004362_113004513 0.06 WNT2B
wingless-type MMTV integration site family, member 2B
4726
0.24
chr16_87840687_87840855 0.06 RP4-536B24.2

29367
0.14
chr5_149340361_149340979 0.06 SLC26A2
solute carrier family 26 (anion exchanger), member 2
322
0.85
chr22_37963047_37963198 0.06 CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
2709
0.17
chr20_52702899_52703050 0.06 BCAS1
breast carcinoma amplified sequence 1
15670
0.21
chr6_74098437_74099264 0.06 ENSG00000238464
.
4886
0.11
chr2_198160747_198160898 0.06 ANKRD44-IT1
ANKRD44 intronic transcript 1 (non-protein coding)
6421
0.18
chr6_82461200_82461724 0.06 FAM46A
family with sequence similarity 46, member A
8
0.98
chr1_27995858_27996192 0.06 RP11-288L9.4

46
0.95
chr15_102286074_102286500 0.06 RP11-89K11.1
Uncharacterized protein
374
0.81
chr11_112096740_112097015 0.06 PTS
6-pyruvoyltetrahydropterin synthase
211
0.89
chr12_44151933_44152435 0.06 PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
377
0.61
chr2_112249108_112249538 0.06 ENSG00000266139
.
170655
0.04
chr19_41305465_41306382 0.06 EGLN2
egl-9 family hypoxia-inducible factor 2
183
0.91
chr11_307271_307422 0.05 IFITM2
interferon induced transmembrane protein 2
285
0.75
chr11_313467_313665 0.05 IFITM1
interferon induced transmembrane protein 1
39
0.92
chr19_6775082_6775336 0.05 VAV1
vav 1 guanine nucleotide exchange factor
2240
0.2
chr7_23530205_23530826 0.05 ENSG00000200847
.
997
0.52
chr12_96591293_96591456 0.05 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
2982
0.28
chr2_87758297_87758504 0.05 RP11-1399P15.1

19153
0.27
chr10_17217419_17217634 0.05 TRDMT1
tRNA aspartic acid methyltransferase 1
867
0.61
chr20_43997209_43997441 0.05 SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
5231
0.12
chr16_11835895_11836525 0.05 RP11-490O6.2

444
0.48
chr19_42381868_42382033 0.05 CD79A
CD79a molecule, immunoglobulin-associated alpha
575
0.62
chr22_39268517_39268976 0.05 CBX6
chromobox homolog 6
427
0.79
chr6_147198107_147198258 0.05 STXBP5-AS1
STXBP5 antisense RNA 1
26041
0.25
chr17_27716871_27717334 0.05 TAOK1
TAO kinase 1
380
0.47
chr16_88768760_88768986 0.05 RNF166
ring finger protein 166
1152
0.23
chr9_132251498_132251652 0.05 ENSG00000264298
.
10740
0.21
chr11_85565230_85565985 0.05 AP000974.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
379
0.6
chr8_66843424_66843611 0.05 PDE7A
phosphodiesterase 7A
89330
0.09
chr10_131652031_131652182 0.05 ENSG00000266676
.
10468
0.24
chr19_33726515_33726666 0.05 SLC7A10
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
9834
0.13
chr17_4457464_4457615 0.05 MYBBP1A
MYB binding protein (P160) 1a
668
0.57
chr14_56381006_56381157 0.05 ENSG00000212522
.
154080
0.04
chr10_126385128_126385308 0.05 FAM53B-AS1
FAM53B antisense RNA 1
6976
0.22
chr10_71318575_71318726 0.05 NEUROG3
neurogenin 3
14344
0.18
chr17_46872784_46872935 0.05 TTLL6
tubulin tyrosine ligase-like family, member 6
1163
0.37
chr14_105948104_105948408 0.05 CRIP1
cysteine-rich protein 1 (intestinal)
4398
0.12
chr2_134880898_134881049 0.05 MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
3220
0.29
chr11_62621592_62621969 0.05 ENSG00000255717
.
23
0.93
chr10_92922169_92922499 0.05 PCGF5
polycomb group ring finger 5
57574
0.16
chr1_201709300_201709781 0.05 NAV1
neuron navigator 1
544
0.66
chr3_155462002_155462501 0.05 PLCH1
phospholipase C, eta 1
605
0.51
chr11_61748704_61748855 0.05 AP003733.1
Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
13326
0.13
chr6_31784100_31784303 0.05 HSPA1L
heat shock 70kDa protein 1-like
764
0.25
chr12_57022963_57023540 0.05 BAZ2A
bromodomain adjacent to zinc finger domain, 2A
744
0.54
chr21_15755875_15756452 0.05 HSPA13
heat shock protein 70kDa family, member 13
655
0.8

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of THRB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.3 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.2 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:1904377 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.0 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling