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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for TLX2

Z-value: 1.77

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Transcription factors associated with TLX2

Gene Symbol	Gene ID	Gene Info
TLX2 Ensembl NCBI GeneCards UniProt	ENSG00000115297.9	T cell leukemia homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_74740717_74740868	TLX2	819	0.311024	0.55	1.3e-01	Click!
chr2_74741123_74741458	TLX2	321	0.690257	-0.33	3.9e-01	Click!
chr2_74742687_74743073	TLX2	1269	0.186878	0.24	5.4e-01	Click!
chr2_74741545_74741780	TLX2	51	0.916197	0.19	6.2e-01	Click!
chr2_74741859_74742032	TLX2	334	0.677498	0.18	6.4e-01	Click!

Activity of the TLX2 motif across conditions

Conditions sorted by the z-value of the TLX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_3627016_3627406	0.95	NLRC3	NLR family, CARD domain containing 3	181	0.93
chr9_117692323_117692779	0.82	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	146	0.98
chr1_84609962_84610447	0.75	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	250	0.95
chr7_142495656_142495944	0.70	PRSS3P2	protease, serine, 3 pseudogene 2	14669	0.17
chr20_50158140_50158637	0.67	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	870	0.72
chr2_204801338_204802214	0.67	ICOS	inducible T-cell co-stimulator	273	0.95
chr4_39032922_39033274	0.66	TMEM156	transmembrane protein 156	943	0.6
chr6_42072028_42072258	0.65	C6orf132	chromosome 6 open reading frame 132	38039	0.11
chr18_21572812_21573447	0.62	TTC39C	tetratricopeptide repeat domain 39C	392	0.85
chr13_46754554_46754849	0.62	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	1758	0.31
chr12_9760266_9760417	0.61	KLRB1	killer cell lectin-like receptor subfamily B, member 1	141	0.94
chr4_90239487_90239778	0.59	GPRIN3	GPRIN family member 3	10471	0.3
chr1_24833351_24833516	0.59	RCAN3	RCAN family member 3	624	0.7
chr2_98330450_98330646	0.55	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	525	0.76
chr10_104195566_104196022	0.54	ENSG00000202569	.	475	0.64
chr16_28997666_28997863	0.54	LAT	linker for activation of T cells	231	0.83
chr2_122493294_122493451	0.53	NIFK	nucleolar protein interacting with the FHA domain of MKI67	9	0.97
chr10_50396086_50396421	0.53	C10orf128	chromosome 10 open reading frame 128	104	0.97
chr6_10528716_10529334	0.53	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	436	0.83
chr14_22946670_22946821	0.53	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	1449	0.24
chr10_130834757_130834924	0.51	MGMT	O-6-methylguanine-DNA methyltransferase	430608	0.01
chr1_25253994_25254145	0.51	RUNX3	runt-related transcription factor 3	1543	0.45
chr1_28832516_28832718	0.51	RCC1	regulator of chromosome condensation 1	48	0.94
chr22_40323194_40323345	0.51	GRAP2	GRB2-related adaptor protein 2	628	0.71
chr6_114716123_114716274	0.50	RP3-399L15.3		30578	0.21
chr10_6192970_6193155	0.50	ENSG00000263628	.	1097	0.36
chr10_105676762_105676966	0.49	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	563	0.75
chr18_8441840_8441991	0.45	ENSG00000242985	.	29914	0.14
chr16_48352531_48352719	0.45	LONP2	lon peptidase 2, peroxisomal	15598	0.2
chr17_36510452_36510603	0.45	SOCS7	suppressor of cytokine signaling 7	1701	0.31
chr2_235397304_235397485	0.45	ARL4C	ADP-ribosylation factor-like 4C	7850	0.33
chr13_40532306_40532606	0.45	ENSG00000212553	.	101092	0.08
chr12_109027255_109027564	0.44	SELPLG	selectin P ligand	261	0.87
chr6_32633978_32634414	0.44	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	233	0.9
chr13_77323974_77324125	0.44	KCTD12	potassium channel tetramerization domain containing 12	136476	0.05
chr3_32993381_32993532	0.44	CCR4	chemokine (C-C motif) receptor 4	390	0.9
chr7_47619037_47619188	0.44	TNS3	tensin 3	2117	0.44
chr15_50411143_50411548	0.43	ATP8B4	ATPase, class I, type 8B, member 4	74	0.98
chr5_74964815_74965486	0.43	ENSG00000207333	.	40274	0.14
chr7_150148744_150149359	0.43	GIMAP8	GTPase, IMAP family member 8	1333	0.41
chr6_106969102_106969411	0.43	AIM1	absent in melanoma 1	9526	0.21
chr11_73692681_73692970	0.43	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	842	0.53
chr9_130678550_130678989	0.43	ST6GALNAC4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	506	0.61
chr17_30475717_30475868	0.42	AC090616.2	Uncharacterized protein	5638	0.14
chr3_46448758_46448964	0.42	CCRL2	chemokine (C-C motif) receptor-like 2	188	0.64
chr22_20783754_20784060	0.42	SCARF2	scavenger receptor class F, member 2	8205	0.11
chr14_71787886_71788130	0.42	SIPA1L1	signal-induced proliferation-associated 1 like 1	100	0.88
chr13_30948639_30948822	0.41	KATNAL1	katanin p60 subunit A-like 1	67109	0.12
chr1_145440326_145440711	0.40	TXNIP	thioredoxin interacting protein	1212	0.33
chr11_6764786_6765082	0.40	GVINP1	GTPase, very large interferon inducible pseudogene 1	21823	0.11
chr6_136201278_136201627	0.40	PDE7B	phosphodiesterase 7B	28618	0.19
chr5_54357840_54358274	0.40	ENSG00000240535	.	19385	0.12
chr19_49621508_49621659	0.40	C19orf73	chromosome 19 open reading frame 73	814	0.31
chrX_118819066_118819466	0.40	SEPT6	septin 6	7526	0.18
chr20_24930187_24930695	0.40	CST7	cystatin F (leukocystatin)	575	0.77
chr3_63953694_63954206	0.39	ATXN7	ataxin 7	530	0.74
chr17_76755164_76755483	0.39	CYTH1	cytohesin 1	22351	0.17
chr16_30345645_30346002	0.39	RP11-347C12.2		552	0.59
chr1_220080705_220080856	0.39	SLC30A10	solute carrier family 30, member 10	21164	0.2
chr8_6131851_6132002	0.39	RP11-115C21.2		132137	0.05
chr11_35147590_35147741	0.38	AL356215.1		2550	0.25
chr14_100543376_100543527	0.38	CTD-2376I20.1		2236	0.24
chr1_75198478_75198729	0.38	CRYZ	crystallin, zeta (quinone reductase)	99	0.69
chrX_45709671_45710004	0.38	ENSG00000212347	.	42577	0.19
chr22_51113449_51114093	0.38	SHANK3	SH3 and multiple ankyrin repeat domains 3	701	0.53
chrX_1327590_1327741	0.38	CRLF2	cytokine receptor-like factor 2	3862	0.22
chr7_30176844_30176995	0.38	MTURN	maturin, neural progenitor differentiation regulator homolog (Xenopus)	44	0.97
chr12_32113291_32114105	0.38	KIAA1551	KIAA1551	1345	0.51
chr3_71539044_71539195	0.38	ENSG00000221264	.	52121	0.14
chr12_32121705_32121856	0.38	KIAA1551	KIAA1551	6357	0.25
chr1_151171487_151171698	0.37	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	541	0.6
chr18_29629660_29629811	0.37	ENSG00000265063	.	11217	0.14
chr6_159464058_159464225	0.36	TAGAP	T-cell activation RhoGTPase activating protein	1909	0.34
chr7_105516175_105516680	0.36	ATXN7L1	ataxin 7-like 1	496	0.88
chr17_40049627_40049778	0.36	ACLY	ATP citrate lyase	25502	0.09
chr1_226900070_226900221	0.36	ITPKB	inositol-trisphosphate 3-kinase B	25014	0.18
chr14_90866152_90866669	0.36	CALM1	calmodulin 1 (phosphorylase kinase, delta)	1804	0.32
chrY_1277584_1277735	0.36	NA	NA	> 10⁶	NA
chr15_52513775_52514010	0.36	GNB5	guanine nucleotide binding protein (G protein), beta 5	30326	0.14
chr22_36635416_36635594	0.35	APOL2	apolipoprotein L, 2	68	0.97
chr3_56788528_56788714	0.35	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	20974	0.24
chr17_62097753_62097982	0.35	ICAM2	intercellular adhesion molecule 2	44	0.97
chr8_133983029_133983180	0.35	TG	thyroglobulin	6252	0.28
chr17_7239932_7240900	0.35	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	507	0.51
chr1_119796838_119796989	0.35	ENSG00000238679	.	4751	0.27
chr18_33550373_33550669	0.35	C18orf21	chromosome 18 open reading frame 21	1525	0.4
chr4_94644030_94644181	0.35	ENSG00000252342	.	97217	0.09
chr6_20336199_20336350	0.34	E2F3	E2F transcription factor 3	66124	0.1
chr10_120839355_120839637	0.34	EIF3A	eukaryotic translation initiation factor 3, subunit A	535	0.7
chr1_89992055_89992206	0.34	LRRC8B	leucine rich repeat containing 8 family, member B	1668	0.45
chr2_231523885_231524103	0.34	CAB39	calcium binding protein 39	53566	0.12
chrX_62780368_62780910	0.34	ENSG00000235437	.	234	0.96
chr5_95157561_95158038	0.34	GLRX	glutaredoxin (thioltransferase)	616	0.67
chr2_54015251_54015402	0.34	ERLEC1	endoplasmic reticulum lectin 1	1109	0.34
chr8_8746534_8747046	0.34	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	4365	0.23
chr19_44284831_44285136	0.33	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	426	0.76
chr22_39713944_39714195	0.33	RPL3	ribosomal protein L3	550	0.53
chr13_30920744_30920895	0.33	KATNAL1	katanin p60 subunit A-like 1	39198	0.18
chr9_19379156_19379414	0.32	RPS6	ribosomal protein S6	911	0.47
chr15_81595958_81596153	0.32	IL16	interleukin 16	4298	0.22
chr2_75873945_75874138	0.32	MRPL19	mitochondrial ribosomal protein L19	64	0.96
chr17_45972566_45972727	0.32	SP2	Sp2 transcription factor	870	0.44
chr8_18067587_18067897	0.32	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)	103	0.98
chr3_69134234_69134646	0.32	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	268	0.88
chr13_40963435_40963699	0.32	ENSG00000252812	.	18010	0.27
chr2_60983411_60983597	0.32	PAPOLG	poly(A) polymerase gamma	139	0.97
chr14_52780039_52780390	0.32	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	809	0.72
chr11_118175872_118176125	0.32	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	384	0.79
chr2_44464528_44464816	0.32	ENSG00000239052	.	2128	0.31
chr12_6601880_6602374	0.32	NCAPD2	non-SMC condensin I complex, subunit D2	418	0.51
chrX_73511926_73512166	0.32	ENSG00000199168	.	4854	0.15
chr16_11448490_11448641	0.32	RP11-485G7.6		5387	0.1
chr4_159999065_159999216	0.32	ENSG00000206978	.	13590	0.16
chr19_12833178_12833372	0.32	TNPO2	transportin 2	64	0.92
chr4_3304601_3305007	0.31	RGS12	regulator of G-protein signaling 12	5958	0.26
chr13_46751053_46751538	0.31	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	5164	0.18
chr17_76122314_76122495	0.31	TMC6	transmembrane channel-like 6	697	0.54
chr19_53466333_53466748	0.31	ZNF816	zinc finger protein 816	376	0.53
chr11_60213804_60213975	0.31	MS4A1	membrane-spanning 4-domains, subfamily A, member 1	9336	0.16
chr9_139636257_139636563	0.31	LCN10	lipocalin 10	945	0.3
chr15_101776262_101776413	0.31	CHSY1	chondroitin sulfate synthase 1	15800	0.17
chr13_46746750_46746965	0.31	ENSG00000240767	.	2974	0.21
chr2_106712942_106713243	0.31	C2orf40	chromosome 2 open reading frame 40	30836	0.19
chr12_14924776_14925101	0.31	HIST4H4	histone cluster 4, H4	873	0.43
chr7_23511681_23511832	0.31	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3	1670	0.34
chr14_75991471_75991622	0.30	BATF	basic leucine zipper transcription factor, ATF-like	2643	0.28
chr1_24831599_24831750	0.30	RCAN3	RCAN family member 3	2287	0.27
chr14_21737001_21737634	0.30	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	234	0.92
chr1_45250267_45250455	0.30	BEST4	bestrophin 4	3016	0.09
chr2_172017767_172018481	0.30	TLK1	tousled-like kinase 1	714	0.74
chr18_67613833_67614105	0.30	CD226	CD226 molecule	686	0.8
chrX_118826490_118826721	0.30	SEPT6	septin 6	187	0.94
chr16_1754586_1754737	0.30	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	1523	0.21
chr12_68383380_68383531	0.29	IFNG-AS1	IFNG antisense RNA 1	146	0.98
chr16_28222592_28222795	0.29	XPO6	exportin 6	104	0.97
chr9_274069_274225	0.29	DOCK8	dedicator of cytokinesis 8	1077	0.39
chr3_25705652_25705988	0.29	TOP2B	topoisomerase (DNA) II beta 180kDa	32	0.93
chr2_68592484_68592752	0.29	AC015969.3		98	0.77
chr1_161735327_161735714	0.29	RP11-474I16.8		497	0.46
chr2_97590421_97590699	0.29	FAM178B	family with sequence similarity 178, member B	26690	0.12
chr6_26440749_26441260	0.29	BTN3A3	butyrophilin, subfamily 3, member A3	218	0.89
chr6_105405945_105406096	0.29	LIN28B	lin-28 homolog B (C. elegans)	1097	0.61
chr2_149633192_149633427	0.29	KIF5C	kinesin family member 5C	490	0.8
chr7_47521347_47521498	0.29	TNS3	tensin 3	539	0.87
chr19_2169086_2169237	0.28	DOT1L	DOT1-like histone H3K79 methyltransferase	4977	0.13
chrX_153627641_153627899	0.28	RPL10	ribosomal protein L10	63	0.9
chr6_33399942_33400093	0.28	SYNGAP1	synaptic Ras GTPase activating protein 1	509	0.65
chr2_108994881_108995032	0.28	SULT1C4	sulfotransferase family, cytosolic, 1C, member 4	315	0.91
chrX_100075462_100075959	0.28	CSTF2	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	185	0.93
chr1_101359723_101359874	0.28	EXTL2	exostosin-like glycosyltransferase 2	422	0.6
chr2_99226461_99226612	0.28	UNC50	unc-50 homolog (C. elegans)	1229	0.4
chr16_30075509_30076103	0.28	ALDOA	aldolase A, fructose-bisphosphate	12	0.94
chr1_92764289_92764538	0.28	RPAP2	RNA polymerase II associated protein 2	109	0.51
chr14_91975547_91976000	0.28	SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	218	0.95
chrX_10435845_10435996	0.28	MID1	midline 1 (Opitz/BBB syndrome)	109075	0.07
chr4_40198272_40198423	0.28	RHOH	ras homolog family member H	180	0.96
chr8_61193398_61193986	0.28	CA8	carbonic anhydrase VIII	279	0.95
chrX_77394376_77395104	0.28	TAF9B	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa	463	0.87
chr6_28108040_28108408	0.28	ZKSCAN8	zinc finger with KRAB and SCAN domains 8	1492	0.26
chr11_47869313_47869770	0.28	NUP160	nucleoporin 160kDa	324	0.88
chr11_60744031_60744182	0.27	CD6	CD6 molecule	4768	0.13
chr10_73529493_73529671	0.27	C10orf54	chromosome 10 open reading frame 54	3673	0.23
chr13_77899440_77899640	0.27	MYCBP2	MYC binding protein 2, E3 ubiquitin protein ligase	1274	0.61
chr3_151963279_151963566	0.27	MBNL1	muscleblind-like splicing regulator 1	22407	0.21
chr12_121570606_121571339	0.27	P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	198	0.94
chr4_48485063_48485286	0.27	SLC10A4	solute carrier family 10, member 4	186	0.95
chr11_14668160_14668311	0.27	PDE3B	phosphodiesterase 3B, cGMP-inhibited	2858	0.29
chr14_102281812_102281963	0.27	CTD-2017C7.2		5229	0.16
chr3_101404556_101405251	0.27	RPL24	ribosomal protein L24	636	0.59
chr10_8068775_8069028	0.27	GATA3	GATA binding protein 3	27755	0.26
chr1_205719608_205719978	0.27	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	389	0.81
chr17_74964898_74965186	0.27	ENSG00000267568	.	137	0.97
chr12_118800306_118800457	0.27	TAOK3	TAO kinase 3	2856	0.32
chr11_118210101_118210326	0.27	CD3D	CD3d molecule, delta (CD3-TCR complex)	1439	0.28
chr4_69215018_69215247	0.27	YTHDC1	YTH domain containing 1	339	0.92
chr3_71354527_71355079	0.27	FOXP1	forkhead box P1	892	0.68
chr5_40841492_40841913	0.27	CARD6	caspase recruitment domain family, member 6	292	0.87
chr1_118154824_118154975	0.27	FAM46C	family with sequence similarity 46, member C	6343	0.23
chr4_103682269_103682620	0.27	MANBA	mannosidase, beta A, lysosomal	293	0.92
chrX_49041049_49041242	0.27	PRICKLE3	prickle homolog 3 (Drosophila)	97	0.92
chr5_149791368_149791565	0.27	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	829	0.6
chr10_96121693_96122003	0.27	NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	137	0.96
chr1_229643787_229644046	0.27	NUP133	nucleoporin 133kDa	157	0.71
chr19_49838375_49839003	0.27	CD37	CD37 molecule	5	0.95
chr1_161038546_161039545	0.27	ARHGAP30	Rho GTPase activating protein 30	411	0.65
chr6_43484850_43485247	0.27	POLR1C	polymerase (RNA) I polypeptide C, 30kDa	198	0.6
chr1_100819629_100819780	0.27	CDC14A	cell division cycle 14A	1199	0.48
chr15_85174382_85174569	0.26	SCAND2P	SCAN domain containing 2 pseudogene	583	0.58
chrX_7061516_7061667	0.26	ENSG00000264268	.	4310	0.26
chr12_89915454_89915947	0.26	GALNT4	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)	2883	0.17
chrX_153190817_153191535	0.26	ARHGAP4	Rho GTPase activating protein 4	522	0.6
chrX_78620829_78620980	0.26	ITM2A	integral membrane protein 2A	1952	0.51
chr7_10978872_10979727	0.26	NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa	584	0.8
chr18_11995997_11996148	0.26	RP11-820I16.3		1135	0.46
chr16_73188487_73188638	0.26	C16orf47	chromosome 16 open reading frame 47	10216	0.28
chr4_71556364_71556515	0.26	UTP3	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	2243	0.18
chr19_19475616_19475786	0.26	GATAD2A	GATA zinc finger domain containing 2A	20934	0.12
chr1_169763319_169763807	0.26	METTL18	methyltransferase like 18	267	0.75
chr11_2324171_2324374	0.26	TSPAN32	tetraspanin 32	174	0.88
chr9_4299316_4299489	0.26	RP11-358M14.2		12	0.91

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.5	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.5	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.4	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.4	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1	0.4	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.2	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.2	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.5	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.2	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.3	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.1	0.3	GO:0045056	transcytosis(GO:0045056)
0.1	0.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.2	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.1	0.2	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1	0.3	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.1	0.3	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	0.2	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.4	GO:0002507	tolerance induction(GO:0002507)
0.1	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.2	GO:0070295	renal water absorption(GO:0070295)
0.1	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.2	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.3	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.1	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.1	0.2	GO:0000239	pachytene(GO:0000239)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.3	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.1	0.2	GO:0015801	aromatic amino acid transport(GO:0015801)
0.1	0.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.4	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.1	0.1	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1	0.4	GO:0033504	floor plate development(GO:0033504)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.1	0.3	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	0.3	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	1.2	GO:0045576	mast cell activation(GO:0045576)
0.0	0.2	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.2	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.2	GO:0060324	face development(GO:0060324)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.2	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0002883	hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.3	GO:0051642	centrosome localization(GO:0051642)
0.0	0.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.2	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.6	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.2	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.4	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0	0.2	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.2	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.2	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.6	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.6	GO:0016578	histone deubiquitination(GO:0016578)
0.0	1.1	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.2	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.6	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.3	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0001743	optic placode formation(GO:0001743)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0035269	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	1.8	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.2	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0042026	protein refolding(GO:0042026)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0043373	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.2	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.0	GO:0046645	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.2	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.2	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.2	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.0	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.0	0.1	GO:0000726	non-recombinational repair(GO:0000726)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.3	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.6	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.2	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.4	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.2	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0045606	positive regulation of epidermal cell differentiation(GO:0045606)
0.0	0.0	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.3	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.4	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.3	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.4	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.3	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.0	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.2	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.2	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0075733	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.1	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.2	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.2	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.8	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.5	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.0	GO:0032202	telomere assembly(GO:0032202)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.2	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.1	GO:0046398	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.3	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0010165	response to X-ray(GO:0010165)
0.0	0.0	GO:0060179	male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0	0.2	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.1	GO:1901984	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.3	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0046632	alpha-beta T cell differentiation(GO:0046632)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.3	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.2	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.1	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.2	GO:0000303	response to superoxide(GO:0000303)
0.0	0.2	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.0	GO:0070303	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0	0.1	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.2	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:1903299	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.9	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.0	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0001881	receptor recycling(GO:0001881)
0.0	0.1	GO:0033233	regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085) regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.3	GO:0070206	protein trimerization(GO:0070206)
0.0	0.3	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.3	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	2.1	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0051095	regulation of helicase activity(GO:0051095)
0.0	0.0	GO:2001259	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0032570	response to progesterone(GO:0032570)
0.0	0.3	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.3	GO:0006490	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.3	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	1.2	GO:0019083	viral gene expression(GO:0019080) viral transcription(GO:0019083)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:0006997	nucleus organization(GO:0006997)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.8	GO:0006364	rRNA processing(GO:0006364)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.3	GO:0036503	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.2	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0006110	regulation of glycolytic process(GO:0006110) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.0	0.0	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.2	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.6	GO:0006754	ATP biosynthetic process(GO:0006754)
0.0	0.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.0	0.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.0	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.0	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0033363	secretory granule organization(GO:0033363)
0.0	0.0	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.2	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.2	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.1	GO:0051225	spindle assembly(GO:0051225)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.4	GO:0022613	ribonucleoprotein complex biogenesis(GO:0022613)
0.0	0.4	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.5	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.0	0.2	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.1	0.9	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.3	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1	0.3	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.7	GO:0001772	immunological synapse(GO:0001772)
0.1	0.7	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.3	GO:0038201	TOR complex(GO:0038201)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	0.3	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.4	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.5	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.4	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.4	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0008278	cohesin complex(GO:0008278)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	1.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	1.2	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	1.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.4	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.3	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.3	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.8	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.6	GO:0009295	nucleoid(GO:0009295)
0.0	2.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.5	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.2	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	1.7	GO:0016607	nuclear speck(GO:0016607)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.9	GO:0015935	small ribosomal subunit(GO:0015935) ribosomal subunit(GO:0044391)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.5	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.5	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.5	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.5	GO:0000793	condensed chromosome(GO:0000793)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.3	GO:0016604	nuclear body(GO:0016604)
0.0	0.3	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.4	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.8	GO:0005681	spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.4	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.4	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.5	GO:0031013	troponin I binding(GO:0031013)
0.1	0.3	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.5	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.3	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.3	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.3	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.2	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.3	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.4	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.3	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.3	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.1	0.2	GO:0046980	tapasin binding(GO:0046980)
0.1	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1	0.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.5	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	1.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.4	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.8	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.5	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.2	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.5	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	2.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.3	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.3	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.9	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.2	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.2	GO:0019843	rRNA binding(GO:0019843)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.4	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.2	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.3	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	3.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.7	GO:0003954	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.5	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.7	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	1.1	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.4	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.2	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.3	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.4	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.6	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.3	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.0	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.3	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.3	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	2.3	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.5	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.7	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	1.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.5	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.5	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network
0.0	0.4	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.7	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.5	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.0	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.4	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.8	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.6	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	2.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.5	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	1.7	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.9	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	1.1	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION	Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.0	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME M G1 TRANSITION	Genes involved in M/G1 Transition
0.0	0.3	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.0	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.0	REACTOME APOPTOSIS	Genes involved in Apoptosis
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition

Results for TLX2

Z-value: 1.77

Motif logo

Transcription factors associated with TLX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TLX2 motif across conditions

Conditions sorted by the z-value of the TLX2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: