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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TLX2

Z-value: 1.77

Motif logo

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Transcription factors associated with TLX2

Gene Symbol Gene ID Gene Info
ENSG00000115297.9 TLX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TLX2chr2_74740717_747408688190.3110240.551.3e-01Click!
TLX2chr2_74741123_747414583210.690257-0.333.9e-01Click!
TLX2chr2_74742687_7474307312690.1868780.245.4e-01Click!
TLX2chr2_74741545_74741780510.9161970.196.2e-01Click!
TLX2chr2_74741859_747420323340.6774980.186.4e-01Click!

Activity of the TLX2 motif across conditions

Conditions sorted by the z-value of the TLX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_3627016_3627406 0.95 NLRC3
NLR family, CARD domain containing 3
181
0.93
chr9_117692323_117692779 0.82 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
146
0.98
chr1_84609962_84610447 0.75 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
250
0.95
chr7_142495656_142495944 0.70 PRSS3P2
protease, serine, 3 pseudogene 2
14669
0.17
chr20_50158140_50158637 0.67 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
870
0.72
chr2_204801338_204802214 0.67 ICOS
inducible T-cell co-stimulator
273
0.95
chr4_39032922_39033274 0.66 TMEM156
transmembrane protein 156
943
0.6
chr6_42072028_42072258 0.65 C6orf132
chromosome 6 open reading frame 132
38039
0.11
chr18_21572812_21573447 0.62 TTC39C
tetratricopeptide repeat domain 39C
392
0.85
chr13_46754554_46754849 0.62 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
1758
0.31
chr12_9760266_9760417 0.61 KLRB1
killer cell lectin-like receptor subfamily B, member 1
141
0.94
chr4_90239487_90239778 0.59 GPRIN3
GPRIN family member 3
10471
0.3
chr1_24833351_24833516 0.59 RCAN3
RCAN family member 3
624
0.7
chr2_98330450_98330646 0.55 ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
525
0.76
chr10_104195566_104196022 0.54 ENSG00000202569
.
475
0.64
chr16_28997666_28997863 0.54 LAT
linker for activation of T cells
231
0.83
chr2_122493294_122493451 0.53 NIFK
nucleolar protein interacting with the FHA domain of MKI67
9
0.97
chr10_50396086_50396421 0.53 C10orf128
chromosome 10 open reading frame 128
104
0.97
chr6_10528716_10529334 0.53 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
436
0.83
chr14_22946670_22946821 0.53 TRAJ60
T cell receptor alpha joining 60 (pseudogene)
1449
0.24
chr10_130834757_130834924 0.51 MGMT
O-6-methylguanine-DNA methyltransferase
430608
0.01
chr1_25253994_25254145 0.51 RUNX3
runt-related transcription factor 3
1543
0.45
chr1_28832516_28832718 0.51 RCC1
regulator of chromosome condensation 1
48
0.94
chr22_40323194_40323345 0.51 GRAP2
GRB2-related adaptor protein 2
628
0.71
chr6_114716123_114716274 0.50 RP3-399L15.3

30578
0.21
chr10_6192970_6193155 0.50 ENSG00000263628
.
1097
0.36
chr10_105676762_105676966 0.49 OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
563
0.75
chr18_8441840_8441991 0.45 ENSG00000242985
.
29914
0.14
chr16_48352531_48352719 0.45 LONP2
lon peptidase 2, peroxisomal
15598
0.2
chr17_36510452_36510603 0.45 SOCS7
suppressor of cytokine signaling 7
1701
0.31
chr2_235397304_235397485 0.45 ARL4C
ADP-ribosylation factor-like 4C
7850
0.33
chr13_40532306_40532606 0.45 ENSG00000212553
.
101092
0.08
chr12_109027255_109027564 0.44 SELPLG
selectin P ligand
261
0.87
chr6_32633978_32634414 0.44 HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
233
0.9
chr13_77323974_77324125 0.44 KCTD12
potassium channel tetramerization domain containing 12
136476
0.05
chr3_32993381_32993532 0.44 CCR4
chemokine (C-C motif) receptor 4
390
0.9
chr7_47619037_47619188 0.44 TNS3
tensin 3
2117
0.44
chr15_50411143_50411548 0.43 ATP8B4
ATPase, class I, type 8B, member 4
74
0.98
chr5_74964815_74965486 0.43 ENSG00000207333
.
40274
0.14
chr7_150148744_150149359 0.43 GIMAP8
GTPase, IMAP family member 8
1333
0.41
chr6_106969102_106969411 0.43 AIM1
absent in melanoma 1
9526
0.21
chr11_73692681_73692970 0.43 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
842
0.53
chr9_130678550_130678989 0.43 ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
506
0.61
chr17_30475717_30475868 0.42 AC090616.2
Uncharacterized protein
5638
0.14
chr3_46448758_46448964 0.42 CCRL2
chemokine (C-C motif) receptor-like 2
188
0.64
chr22_20783754_20784060 0.42 SCARF2
scavenger receptor class F, member 2
8205
0.11
chr14_71787886_71788130 0.42 SIPA1L1
signal-induced proliferation-associated 1 like 1
100
0.88
chr13_30948639_30948822 0.41 KATNAL1
katanin p60 subunit A-like 1
67109
0.12
chr1_145440326_145440711 0.40 TXNIP
thioredoxin interacting protein
1212
0.33
chr11_6764786_6765082 0.40 GVINP1
GTPase, very large interferon inducible pseudogene 1
21823
0.11
chr6_136201278_136201627 0.40 PDE7B
phosphodiesterase 7B
28618
0.19
chr5_54357840_54358274 0.40 ENSG00000240535
.
19385
0.12
chr19_49621508_49621659 0.40 C19orf73
chromosome 19 open reading frame 73
814
0.31
chrX_118819066_118819466 0.40 SEPT6
septin 6
7526
0.18
chr20_24930187_24930695 0.40 CST7
cystatin F (leukocystatin)
575
0.77
chr3_63953694_63954206 0.39 ATXN7
ataxin 7
530
0.74
chr17_76755164_76755483 0.39 CYTH1
cytohesin 1
22351
0.17
chr16_30345645_30346002 0.39 RP11-347C12.2

552
0.59
chr1_220080705_220080856 0.39 SLC30A10
solute carrier family 30, member 10
21164
0.2
chr8_6131851_6132002 0.39 RP11-115C21.2

132137
0.05
chr11_35147590_35147741 0.38 AL356215.1

2550
0.25
chr14_100543376_100543527 0.38 CTD-2376I20.1

2236
0.24
chr1_75198478_75198729 0.38 CRYZ
crystallin, zeta (quinone reductase)
99
0.69
chrX_45709671_45710004 0.38 ENSG00000212347
.
42577
0.19
chr22_51113449_51114093 0.38 SHANK3
SH3 and multiple ankyrin repeat domains 3
701
0.53
chrX_1327590_1327741 0.38 CRLF2
cytokine receptor-like factor 2
3862
0.22
chr7_30176844_30176995 0.38 MTURN
maturin, neural progenitor differentiation regulator homolog (Xenopus)
44
0.97
chr12_32113291_32114105 0.38 KIAA1551
KIAA1551
1345
0.51
chr3_71539044_71539195 0.38 ENSG00000221264
.
52121
0.14
chr12_32121705_32121856 0.38 KIAA1551
KIAA1551
6357
0.25
chr1_151171487_151171698 0.37 PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
541
0.6
chr18_29629660_29629811 0.37 ENSG00000265063
.
11217
0.14
chr6_159464058_159464225 0.36 TAGAP
T-cell activation RhoGTPase activating protein
1909
0.34
chr7_105516175_105516680 0.36 ATXN7L1
ataxin 7-like 1
496
0.88
chr17_40049627_40049778 0.36 ACLY
ATP citrate lyase
25502
0.09
chr1_226900070_226900221 0.36 ITPKB
inositol-trisphosphate 3-kinase B
25014
0.18
chr14_90866152_90866669 0.36 CALM1
calmodulin 1 (phosphorylase kinase, delta)
1804
0.32
chrY_1277584_1277735 0.36 NA
NA
> 106
NA
chr15_52513775_52514010 0.36 GNB5
guanine nucleotide binding protein (G protein), beta 5
30326
0.14
chr22_36635416_36635594 0.35 APOL2
apolipoprotein L, 2
68
0.97
chr3_56788528_56788714 0.35 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
20974
0.24
chr17_62097753_62097982 0.35 ICAM2
intercellular adhesion molecule 2
44
0.97
chr8_133983029_133983180 0.35 TG
thyroglobulin
6252
0.28
chr17_7239932_7240900 0.35 ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
507
0.51
chr1_119796838_119796989 0.35 ENSG00000238679
.
4751
0.27
chr18_33550373_33550669 0.35 C18orf21
chromosome 18 open reading frame 21
1525
0.4
chr4_94644030_94644181 0.35 ENSG00000252342
.
97217
0.09
chr6_20336199_20336350 0.34 E2F3
E2F transcription factor 3
66124
0.1
chr10_120839355_120839637 0.34 EIF3A
eukaryotic translation initiation factor 3, subunit A
535
0.7
chr1_89992055_89992206 0.34 LRRC8B
leucine rich repeat containing 8 family, member B
1668
0.45
chr2_231523885_231524103 0.34 CAB39
calcium binding protein 39
53566
0.12
chrX_62780368_62780910 0.34 ENSG00000235437
.
234
0.96
chr5_95157561_95158038 0.34 GLRX
glutaredoxin (thioltransferase)
616
0.67
chr2_54015251_54015402 0.34 ERLEC1
endoplasmic reticulum lectin 1
1109
0.34
chr8_8746534_8747046 0.34 MFHAS1
malignant fibrous histiocytoma amplified sequence 1
4365
0.23
chr19_44284831_44285136 0.33 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
426
0.76
chr22_39713944_39714195 0.33 RPL3
ribosomal protein L3
550
0.53
chr13_30920744_30920895 0.33 KATNAL1
katanin p60 subunit A-like 1
39198
0.18
chr9_19379156_19379414 0.32 RPS6
ribosomal protein S6
911
0.47
chr15_81595958_81596153 0.32 IL16
interleukin 16
4298
0.22
chr2_75873945_75874138 0.32 MRPL19
mitochondrial ribosomal protein L19
64
0.96
chr17_45972566_45972727 0.32 SP2
Sp2 transcription factor
870
0.44
chr8_18067587_18067897 0.32 NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
103
0.98
chr3_69134234_69134646 0.32 ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
268
0.88
chr13_40963435_40963699 0.32 ENSG00000252812
.
18010
0.27
chr2_60983411_60983597 0.32 PAPOLG
poly(A) polymerase gamma
139
0.97
chr14_52780039_52780390 0.32 PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
809
0.72
chr11_118175872_118176125 0.32 CD3E
CD3e molecule, epsilon (CD3-TCR complex)
384
0.79
chr2_44464528_44464816 0.32 ENSG00000239052
.
2128
0.31
chr12_6601880_6602374 0.32 NCAPD2
non-SMC condensin I complex, subunit D2
418
0.51
chrX_73511926_73512166 0.32 ENSG00000199168
.
4854
0.15
chr16_11448490_11448641 0.32 RP11-485G7.6

5387
0.1
chr4_159999065_159999216 0.32 ENSG00000206978
.
13590
0.16
chr19_12833178_12833372 0.32 TNPO2
transportin 2
64
0.92
chr4_3304601_3305007 0.31 RGS12
regulator of G-protein signaling 12
5958
0.26
chr13_46751053_46751538 0.31 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
5164
0.18
chr17_76122314_76122495 0.31 TMC6
transmembrane channel-like 6
697
0.54
chr19_53466333_53466748 0.31 ZNF816
zinc finger protein 816
376
0.53
chr11_60213804_60213975 0.31 MS4A1
membrane-spanning 4-domains, subfamily A, member 1
9336
0.16
chr9_139636257_139636563 0.31 LCN10
lipocalin 10
945
0.3
chr15_101776262_101776413 0.31 CHSY1
chondroitin sulfate synthase 1
15800
0.17
chr13_46746750_46746965 0.31 ENSG00000240767
.
2974
0.21
chr2_106712942_106713243 0.31 C2orf40
chromosome 2 open reading frame 40
30836
0.19
chr12_14924776_14925101 0.31 HIST4H4
histone cluster 4, H4
873
0.43
chr7_23511681_23511832 0.31 IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
1670
0.34
chr14_75991471_75991622 0.30 BATF
basic leucine zipper transcription factor, ATF-like
2643
0.28
chr1_24831599_24831750 0.30 RCAN3
RCAN family member 3
2287
0.27
chr14_21737001_21737634 0.30 HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
234
0.92
chr1_45250267_45250455 0.30 BEST4
bestrophin 4
3016
0.09
chr2_172017767_172018481 0.30 TLK1
tousled-like kinase 1
714
0.74
chr18_67613833_67614105 0.30 CD226
CD226 molecule
686
0.8
chrX_118826490_118826721 0.30 SEPT6
septin 6
187
0.94
chr16_1754586_1754737 0.30 MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
1523
0.21
chr12_68383380_68383531 0.29 IFNG-AS1
IFNG antisense RNA 1
146
0.98
chr16_28222592_28222795 0.29 XPO6
exportin 6
104
0.97
chr9_274069_274225 0.29 DOCK8
dedicator of cytokinesis 8
1077
0.39
chr3_25705652_25705988 0.29 TOP2B
topoisomerase (DNA) II beta 180kDa
32
0.93
chr2_68592484_68592752 0.29 AC015969.3

98
0.77
chr1_161735327_161735714 0.29 RP11-474I16.8

497
0.46
chr2_97590421_97590699 0.29 FAM178B
family with sequence similarity 178, member B
26690
0.12
chr6_26440749_26441260 0.29 BTN3A3
butyrophilin, subfamily 3, member A3
218
0.89
chr6_105405945_105406096 0.29 LIN28B
lin-28 homolog B (C. elegans)
1097
0.61
chr2_149633192_149633427 0.29 KIF5C
kinesin family member 5C
490
0.8
chr7_47521347_47521498 0.29 TNS3
tensin 3
539
0.87
chr19_2169086_2169237 0.28 DOT1L
DOT1-like histone H3K79 methyltransferase
4977
0.13
chrX_153627641_153627899 0.28 RPL10
ribosomal protein L10
63
0.9
chr6_33399942_33400093 0.28 SYNGAP1
synaptic Ras GTPase activating protein 1
509
0.65
chr2_108994881_108995032 0.28 SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
315
0.91
chrX_100075462_100075959 0.28 CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
185
0.93
chr1_101359723_101359874 0.28 EXTL2
exostosin-like glycosyltransferase 2
422
0.6
chr2_99226461_99226612 0.28 UNC50
unc-50 homolog (C. elegans)
1229
0.4
chr16_30075509_30076103 0.28 ALDOA
aldolase A, fructose-bisphosphate
12
0.94
chr1_92764289_92764538 0.28 RPAP2
RNA polymerase II associated protein 2
109
0.51
chr14_91975547_91976000 0.28 SMEK1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
218
0.95
chrX_10435845_10435996 0.28 MID1
midline 1 (Opitz/BBB syndrome)
109075
0.07
chr4_40198272_40198423 0.28 RHOH
ras homolog family member H
180
0.96
chr8_61193398_61193986 0.28 CA8
carbonic anhydrase VIII
279
0.95
chrX_77394376_77395104 0.28 TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
463
0.87
chr6_28108040_28108408 0.28 ZKSCAN8
zinc finger with KRAB and SCAN domains 8
1492
0.26
chr11_47869313_47869770 0.28 NUP160
nucleoporin 160kDa
324
0.88
chr11_60744031_60744182 0.27 CD6
CD6 molecule
4768
0.13
chr10_73529493_73529671 0.27 C10orf54
chromosome 10 open reading frame 54
3673
0.23
chr13_77899440_77899640 0.27 MYCBP2
MYC binding protein 2, E3 ubiquitin protein ligase
1274
0.61
chr3_151963279_151963566 0.27 MBNL1
muscleblind-like splicing regulator 1
22407
0.21
chr12_121570606_121571339 0.27 P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
198
0.94
chr4_48485063_48485286 0.27 SLC10A4
solute carrier family 10, member 4
186
0.95
chr11_14668160_14668311 0.27 PDE3B
phosphodiesterase 3B, cGMP-inhibited
2858
0.29
chr14_102281812_102281963 0.27 CTD-2017C7.2

5229
0.16
chr3_101404556_101405251 0.27 RPL24
ribosomal protein L24
636
0.59
chr10_8068775_8069028 0.27 GATA3
GATA binding protein 3
27755
0.26
chr1_205719608_205719978 0.27 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
389
0.81
chr17_74964898_74965186 0.27 ENSG00000267568
.
137
0.97
chr12_118800306_118800457 0.27 TAOK3
TAO kinase 3
2856
0.32
chr11_118210101_118210326 0.27 CD3D
CD3d molecule, delta (CD3-TCR complex)
1439
0.28
chr4_69215018_69215247 0.27 YTHDC1
YTH domain containing 1
339
0.92
chr3_71354527_71355079 0.27 FOXP1
forkhead box P1
892
0.68
chr5_40841492_40841913 0.27 CARD6
caspase recruitment domain family, member 6
292
0.87
chr1_118154824_118154975 0.27 FAM46C
family with sequence similarity 46, member C
6343
0.23
chr4_103682269_103682620 0.27 MANBA
mannosidase, beta A, lysosomal
293
0.92
chrX_49041049_49041242 0.27 PRICKLE3
prickle homolog 3 (Drosophila)
97
0.92
chr5_149791368_149791565 0.27 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
829
0.6
chr10_96121693_96122003 0.27 NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
137
0.96
chr1_229643787_229644046 0.27 NUP133
nucleoporin 133kDa
157
0.71
chr19_49838375_49839003 0.27 CD37
CD37 molecule
5
0.95
chr1_161038546_161039545 0.27 ARHGAP30
Rho GTPase activating protein 30
411
0.65
chr6_43484850_43485247 0.27 POLR1C
polymerase (RNA) I polypeptide C, 30kDa
198
0.6
chr1_100819629_100819780 0.27 CDC14A
cell division cycle 14A
1199
0.48
chr15_85174382_85174569 0.26 SCAND2P
SCAN domain containing 2 pseudogene
583
0.58
chrX_7061516_7061667 0.26 ENSG00000264268
.
4310
0.26
chr12_89915454_89915947 0.26 GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
2883
0.17
chrX_153190817_153191535 0.26 ARHGAP4
Rho GTPase activating protein 4
522
0.6
chrX_78620829_78620980 0.26 ITM2A
integral membrane protein 2A
1952
0.51
chr7_10978872_10979727 0.26 NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
584
0.8
chr18_11995997_11996148 0.26 RP11-820I16.3

1135
0.46
chr16_73188487_73188638 0.26 C16orf47
chromosome 16 open reading frame 47
10216
0.28
chr4_71556364_71556515 0.26 UTP3
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
2243
0.18
chr19_19475616_19475786 0.26 GATAD2A
GATA zinc finger domain containing 2A
20934
0.12
chr1_169763319_169763807 0.26 METTL18
methyltransferase like 18
267
0.75
chr11_2324171_2324374 0.26 TSPAN32
tetraspanin 32
174
0.88
chr9_4299316_4299489 0.26 RP11-358M14.2

12
0.91

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TLX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.5 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.5 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.5 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.4 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.4 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 0.5 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.2 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1 0.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.3 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.4 GO:0002507 tolerance induction(GO:0002507)
0.1 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.2 GO:0070295 renal water absorption(GO:0070295)
0.1 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 0.2 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.2 GO:0097576 vacuole fusion(GO:0097576)
0.1 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.1 0.1 GO:0048143 astrocyte activation(GO:0048143)
0.1 0.2 GO:0000239 pachytene(GO:0000239)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.1 0.2 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1 0.4 GO:0033504 floor plate development(GO:0033504)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.1 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.3 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.1 0.2 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 1.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0060324 face development(GO:0060324)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0002883 hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.4 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.2 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.6 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 1.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.3 GO:0051383 kinetochore organization(GO:0051383)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.8 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0042026 protein refolding(GO:0042026)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0043373 T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.0 GO:0046645 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.2 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.2 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.0 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.1 GO:0000726 non-recombinational repair(GO:0000726)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.2 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0045606 positive regulation of epidermal cell differentiation(GO:0045606)
0.0 0.0 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.2 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0075733 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.2 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.0 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0032202 telomere assembly(GO:0032202)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0075713 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.1 GO:0046398 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.0 GO:0060179 male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0 0.2 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.0 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.1 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:1903299 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.0 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0001881 receptor recycling(GO:0001881)
0.0 0.1 GO:0033233 regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085) regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0043102 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 2.1 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0051095 regulation of helicase activity(GO:0051095)
0.0 0.0 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.0 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.0 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 1.2 GO:0019083 viral gene expression(GO:0019080) viral transcription(GO:0019083)
0.0 0.2 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0006997 nucleus organization(GO:0006997)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.8 GO:0006364 rRNA processing(GO:0006364)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.3 GO:0036503 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0 0.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.1 GO:0006110 regulation of glycolytic process(GO:0006110) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.6 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.0 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0033363 secretory granule organization(GO:0033363)
0.0 0.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:0015853 adenine transport(GO:0015853)
0.0 0.0 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.1 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.1 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.4 GO:0022613 ribonucleoprotein complex biogenesis(GO:0022613)
0.0 0.4 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.5 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1 0.3 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:0038201 TOR complex(GO:0038201)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0097525 spliceosomal snRNP complex(GO:0097525)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.6 GO:0009295 nucleoid(GO:0009295)
0.0 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.5 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.9 GO:0015935 small ribosomal subunit(GO:0015935) ribosomal subunit(GO:0044391)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.5 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0016604 nuclear body(GO:0016604)
0.0 0.3 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 0.2 GO:0046980 tapasin binding(GO:0046980)
0.1 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.5 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.5 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.7 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.6 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 2.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.0 PID SHP2 PATHWAY SHP2 signaling
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.7 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.0 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.0 0.3 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.0 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.0 REACTOME APOPTOSIS Genes involved in Apoptosis
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition