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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for TP53

Z-value: 1.49

Motif logo

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
TP53
ENSG00000141510.11 tumor protein p53

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_7590649_7590937TP5360.494120-0.294.6e-01Click!
chr17_7590956_7591177TP532100.564802-0.215.8e-01Click!
chr17_7590042_7590608TP534200.348590-0.127.6e-01Click!

Activity of the TP53 motif across conditions

Conditions sorted by the z-value of the TP53 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_72439858_72440009 1.16 TRIM74
 tripartite motif containing 74
 64
 0.95
chr7_75024883_75025034 1.02 TRIM73
 tripartite motif containing 73
 55
 0.84
chr21_36077269_36077677 0.89 CLIC6
 chloride intracellular channel 6
 35785
 0.17
chr1_116381723_116382451 0.75 NHLH2
 nescient helix loop helix 2
 1275
 0.57
chr1_16950904_16951055 0.75 NBPF1
 neuroblastoma breakpoint family, member 1
 10997
 0.14
chr10_5566796_5566947 0.75 CALML3
 calmodulin-like 3
 53
 0.92
chr9_110011481_110011632 0.75 RAD23B
 RAD23 homolog B (S. cerevisiae)
 33862
 0.22
chr4_1760272_1760423 0.72 TACC3
 transforming, acidic coiled-coil containing protein 3
 30216
 0.12
chrX_113309122_113309273 0.70 ENSG00000212611
 .
 48936
 0.16
chr7_2019823_2019974 0.66 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 528
 0.86
chr11_706564_706815 0.65 EPS8L2
 EPS8-like 2
 60
 0.94
chr19_45313552_45313703 0.65 BCAM
 basal cell adhesion molecule (Lutheran blood group)
 1249
 0.33
chr9_131865142_131865293 0.64 ENSG00000221521
 .
 4213
 0.12
chr9_129263535_129263686 0.63 ENSG00000221768
 .
 29660
 0.17
chr17_35718321_35718472 0.62 ACACA
 acetyl-CoA carboxylase alpha
 2337
 0.25
chr11_1328574_1328800 0.60 TOLLIP
 toll interacting protein
 2162
 0.23
chr4_54968164_54968315 0.59 ENSG00000221219
 .
 1584
 0.3
chr9_132094734_132094885 0.59 ENSG00000242281
 .
 37931
 0.16
chr5_1004071_1004222 0.58 ENSG00000221244
 .
 156
 0.93
chr16_29262868_29263019 0.58 RP11-231C14.6
60728
 0.09
chr10_119303143_119303333 0.57 EMX2
 empty spiracles homeobox 2
 729
 0.61
chr22_20887250_20887401 0.55 MED15
 mediator complex subunit 15
 8763
 0.12
chr18_28622614_28622900 0.54 DSC3
 desmocollin 3
 24
 0.98
chr22_46480425_46480827 0.54 FLJ27365
 hsa-mir-4763
 1257
 0.28
chr4_157692546_157692809 0.54 RP11-154F14.2
69834
 0.11
chr17_4463313_4463464 0.53 GGT6
 gamma-glutamyltransferase 6
 158
 0.92
chr15_41913046_41914152 0.53 MGA
 MGA, MAX dimerization protein
 135
 0.96
chr16_902323_902474 0.52 LA16c-306A4.1
31382
 0.08
chr16_67213263_67213414 0.52 KIAA0895L
 KIAA0895-like
 627
 0.43
chr1_177139870_177140730 0.51 BRINP2
 bone morphogenetic protein/retinoic acid inducible neural-specific 2
 333
 0.89
chr1_145543160_145543350 0.50 RP11-315I20.3
1026
 0.34
chr16_57654156_57654307 0.49 GPR56
 G protein-coupled receptor 56
 215
 0.92
chr11_119567368_119567519 0.48 PVRL1
 poliovirus receptor-related 1 (herpesvirus entry mediator C)
 31820
 0.14
chr11_8111770_8111921 0.47 TUB
 tubby bipartite transcription factor
 8936
 0.16
chr3_124913489_124913640 0.47 SLC12A8
 solute carrier family 12, member 8
 2025
 0.37
chr2_214334_214485 0.46 AC079779.7
16840
 0.18
chr20_61003066_61003217 0.46 RBBP8NL
 RBBP8 N-terminal like
 552
 0.7
chr19_19446684_19446835 0.46 MAU2
 MAU2 sister chromatid cohesion factor
 1256
 0.36
chr3_55520023_55520469 0.45 WNT5A
 wingless-type MMTV integration site family, member 5A
 1085
 0.48
chr22_46474299_46474631 0.45 FLJ27365
 hsa-mir-4763
 1727
 0.2
chr16_54459980_54460131 0.45 ENSG00000264079
 .
 123253
 0.06
chr11_129061773_129061924 0.44 ARHGAP32
 Rho GTPase activating protein 32
 245
 0.94
chr6_46620180_46620625 0.44 CYP39A1
 cytochrome P450, family 39, subfamily A, polypeptide 1
 121
 0.71
chr12_54519921_54520255 0.44 ENSG00000202146
 .
 27002
 0.09
chr2_232544960_232545111 0.44 MGC4771
26586
 0.13
chr7_67474743_67474894 0.44 ENSG00000265600
 .
 653151
 0.0
chr8_21959623_21959774 0.44 NUDT18
 nudix (nucleoside diphosphate linked moiety X)-type motif 18
 7212
 0.11
chr14_104638147_104638298 0.44 KIF26A
 kinesin family member 26A
 32845
 0.13
chr6_34122459_34122617 0.44 GRM4
 glutamate receptor, metabotropic 4
 861
 0.68
chr14_76843049_76843200 0.44 ENSG00000263880
 .
 21772
 0.18
chr19_28285219_28285519 0.43 AC005758.1
124482
 0.06
chr16_57687976_57688127 0.43 GPR56
 G protein-coupled receptor 56
 908
 0.48
chr22_35715502_35715653 0.43 TOM1
 target of myb1 (chicken)
 8522
 0.16
chr2_137522313_137522464 0.42 THSD7B
 thrombospondin, type I, domain containing 7B
 727
 0.8
chr8_144960354_144960505 0.42 EPPK1
 epiplakin 1
 7797
 0.11
chr18_45599789_45599940 0.42 ZBTB7C
 zinc finger and BTB domain containing 7C
 32370
 0.22
chr17_37031531_37031718 0.42 LASP1
 LIM and SH3 protein 1
 1481
 0.23
chr17_37760675_37760938 0.42 NEUROD2
 neuronal differentiation 2
 3390
 0.17
chr8_10588268_10588485 0.41 SOX7
 SRY (sex determining region Y)-box 7
 354
 0.78
chr12_54391177_54391923 0.41 HOXC-AS2
 HOXC cluster antisense RNA 2
 981
 0.22
chrX_153029718_153029902 0.41 PLXNB3
 plexin B3
 84
 0.93
chr11_75152424_75152575 0.41 GDPD5
 glycerophosphodiester phosphodiesterase domain containing 5
 268
 0.88
chr14_105332332_105332761 0.41 CEP170B
 centrosomal protein 170B
 892
 0.57
chr1_38465984_38466787 0.41 FHL3
 four and a half LIM domains 3
 4792
 0.14
chr4_96461530_96461681 0.41 UNC5C
 unc-5 homolog C (C. elegans)
 8518
 0.25
chr11_65666484_65666730 0.41 FOSL1
 FOS-like antigen 1
 1283
 0.23
chr11_64073389_64074392 0.40 ESRRA
 estrogen-related receptor alpha
 28
 0.92
chr8_96237876_96238027 0.40 C8orf37
 chromosome 8 open reading frame 37
 43478
 0.17
chr19_18475720_18476136 0.40 PGPEP1
 pyroglutamyl-peptidase I
 7612
 0.09
chr8_69242814_69243988 0.40 C8orf34
 chromosome 8 open reading frame 34
 56
 0.82
chr19_35589604_35589755 0.40 AC020907.1
 Uncharacterized protein
 7194
 0.1
chr1_113392388_113392874 0.40 SLC16A1
 solute carrier family 16 (monocarboxylate transporter), member 1
 85979
 0.07
chr1_6085866_6086187 0.40 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
 334
 0.88
chr7_129420780_129420931 0.40 ENSG00000207691
 .
 6001
 0.16
chr3_182879726_182880740 0.40 LAMP3
 lysosomal-associated membrane protein 3
 430
 0.86
chr19_56652318_56652782 0.39 ZNF444
 zinc finger protein 444
 6
 0.96
chr17_79056077_79056228 0.39 BAIAP2
 BAI1-associated protein 2
 4109
 0.15
chr21_44872011_44872162 0.39 SIK1
 salt-inducible kinase 1
 25078
 0.24
chr1_107682797_107683388 0.39 NTNG1
 netrin G1
 350
 0.93
chr12_26379464_26379833 0.39 SSPN
 sarcospan
 31042
 0.17
chr16_89118855_89119113 0.39 ACSF3
 acyl-CoA synthetase family member 3
 35799
 0.13
chr22_46861776_46861927 0.39 CELSR1
 cadherin, EGF LAG seven-pass G-type receptor 1
 69340
 0.1
chr1_221166154_221166305 0.38 HLX
 H2.0-like homeobox
 111645
 0.06
chr19_30159686_30159837 0.38 PLEKHF1
 pleckstrin homology domain containing, family F (with FYVE domain) member 1
 1980
 0.38
chr10_99309798_99309949 0.38 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
 22325
 0.1
chr22_43523383_43523534 0.38 MCAT
 malonyl CoA:ACP acyltransferase (mitochondrial)
 15512
 0.13
chr9_139493449_139493600 0.38 ENSG00000252440
 .
 3443
 0.14
chr4_48988009_48988286 0.38 CWH43
 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
 117
 0.97
chr19_4010009_4010213 0.37 PIAS4
 protein inhibitor of activated STAT, 4
 2467
 0.16
chr19_17905710_17906188 0.37 B3GNT3
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
 4
 0.96
chr1_201253218_201253369 0.37 PKP1
 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
 462
 0.83
chr12_56546304_56546955 0.37 MYL6B
 myosin, light chain 6B, alkali, smooth muscle and non-muscle
 238
 0.78
chr3_187491387_187491633 0.37 BCL6
 B-cell CLL/lymphoma 6
 27995
 0.2
chr20_22807182_22807333 0.37 ENSG00000265151
 .
 93318
 0.08
chr20_48766370_48766669 0.37 TMEM189-UBE2V1
 TMEM189-UBE2V1 readthrough
 3655
 0.2
chr11_2824838_2824989 0.37 KCNQ1-AS1
 KCNQ1 antisense RNA 1
 57885
 0.09
chr7_738673_738824 0.37 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
 7317
 0.21
chr18_8706613_8707165 0.37 SOGA2
 SOGA family member 2
 520
 0.55
chr1_149858479_149859475 0.37 HIST2H2AC
 histone cluster 2, H2ac
 452
 0.26
chr2_213793107_213793258 0.37 ENSG00000266354
 .
 2201
 0.44
chr11_2230168_2230319 0.36 ENSG00000265258
 .
 35950
 0.09
chr22_46465997_46466532 0.36 RP6-109B7.4
493
 0.65
chr19_41847932_41848083 0.36 TGFB1
 transforming growth factor, beta 1
 72
 0.94
chr10_119301594_119301816 0.36 EMX2OS
 EMX2 opposite strand/antisense RNA
 125
 0.68
chr1_154785958_154786192 0.36 KCNN3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
 46244
 0.11
chr16_787839_787990 0.36 NARFL
 nuclear prelamin A recognition factor-like
 25
 0.92
chr3_46671629_46671864 0.36 ENSG00000251967
 .
 20254
 0.13
chr22_50630477_50630948 0.36 RP3-402G11.25
119
 0.86
chr6_158181766_158181950 0.36 SNX9
 sorting nexin 9
 62438
 0.11
chr13_102068774_102068925 0.36 NALCN
 sodium leak channel, non-selective
 65
 0.98
chr21_36216765_36216916 0.36 RUNX1
 runt-related transcription factor 1
 42640
 0.19
chr2_75787847_75788044 0.36 EVA1A
 eva-1 homolog A (C. elegans)
 94
 0.97
chr11_6340744_6340939 0.36 PRKCDBP
 protein kinase C, delta binding protein
 921
 0.53
chr5_131729150_131729301 0.36 C5orf56
 chromosome 5 open reading frame 56
 17103
 0.11
chr1_16480833_16481011 0.36 RP11-276H7.2
784
 0.46
chr8_22576706_22576857 0.35 EGR3
 early growth response 3
 25966
 0.12
chr11_12132812_12133164 0.35 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 850
 0.73
chr1_45806125_45806469 0.35 MUTYH
 mutY homolog
 155
 0.84
chr6_44030171_44030322 0.35 RP5-1120P11.1
12143
 0.17
chr5_149315304_149315455 0.35 ENSG00000200334
 .
 4315
 0.18
chr9_98225406_98225667 0.35 PTCH1
 patched 1
 17231
 0.18
chr9_130831197_130832052 0.35 SLC25A25
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
 1052
 0.31
chr10_105842975_105843126 0.35 COL17A1
 collagen, type XVII, alpha 1
 2486
 0.27
chr1_6418349_6418500 0.35 ACOT7
 acyl-CoA thioesterase 7
 980
 0.49
chr16_70624804_70624955 0.34 IL34
 interleukin 34
 11067
 0.15
chr19_35609321_35609472 0.34 FXYD3
 FXYD domain containing ion transport regulator 3
 38
 0.95
chr9_130186748_130187435 0.34 ZNF79
 zinc finger protein 79
 374
 0.8
chr17_73567230_73567381 0.34 MYO15B
 myosin XVB pseudogene
 19553
 0.1
chr11_34175761_34176017 0.34 ENSG00000201867
 .
 34832
 0.18
chr10_134211385_134212056 0.34 PWWP2B
 PWWP domain containing 2B
 1018
 0.54
chr20_61002159_61002310 0.34 RBBP8NL
 RBBP8 N-terminal like
 355
 0.83
chr10_106034668_106034899 0.34 GSTO2
 glutathione S-transferase omega 2
 134
 0.94
chr7_99754005_99754156 0.34 C7orf43
 chromosome 7 open reading frame 43
 17
 0.71
chr21_46824152_46824303 0.34 COL18A1
 collagen, type XVIII, alpha 1
 825
 0.56
chr1_2345264_2345415 0.34 PEX10
 peroxisomal biogenesis factor 10
 103
 0.94
chr3_48468926_48469077 0.33 PLXNB1
 plexin B1
 1871
 0.18
chr19_16396913_16397119 0.33 CTD-2562J15.6
7370
 0.17
chr3_126006504_126006736 0.33 KLF15
 Kruppel-like factor 15
 69665
 0.08
chr6_161454686_161454957 0.33 MAP3K4
 mitogen-activated protein kinase kinase kinase 4
 11595
 0.25
chr10_16483414_16483776 0.33 PTER
 phosphotriesterase related
 4612
 0.25
chr1_9241794_9242495 0.33 ENSG00000207865
 .
 30308
 0.15
chr17_32947230_32947381 0.33 TMEM132E
 transmembrane protein 132E
 39537
 0.17
chr13_77343113_77343264 0.33 KCTD12
 potassium channel tetramerization domain containing 12
 117337
 0.06
chr19_4374282_4374693 0.32 SH3GL1
 SH3-domain GRB2-like 1
 5802
 0.08
chr5_178487316_178488173 0.32 ZNF354C
 zinc finger protein 354C
 328
 0.9
chr16_69134943_69135094 0.32 HAS3
 hyaluronan synthase 3
 4449
 0.18
chr1_234793534_234793917 0.32 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 48454
 0.13
chr15_40532500_40532651 0.32 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
 148
 0.93
chr8_41166402_41166711 0.32 SFRP1
 secreted frizzled-related protein 1
 460
 0.8
chr6_33547162_33547696 0.32 BAK1
 BCL2-antagonist/killer 1
 552
 0.67
chr6_53493330_53493549 0.32 RP11-345L23.1
261
 0.92
chr20_22565035_22565186 0.32 FOXA2
 forkhead box A2
 9
 0.99
chr7_4046197_4046504 0.31 SDK1
 sidekick cell adhesion molecule 1
 55798
 0.18
chr18_67959305_67959456 0.31 SOCS6
 suppressor of cytokine signaling 6
 3243
 0.3
chr2_220154476_220154679 0.31 ENSG00000207647
 .
 4345
 0.09
chr8_102039581_102039732 0.31 ENSG00000252736
 .
 64385
 0.1
chr6_36089175_36089326 0.31 MAPK13
 mitogen-activated protein kinase 13
 8848
 0.18
chr8_144682749_144682900 0.31 EEF1D
 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
 1113
 0.23
chr1_55525795_55525946 0.31 PCSK9
 proprotein convertase subtilisin/kexin type 9
 19975
 0.19
chr1_61668583_61669016 0.31 RP4-802A10.1
78394
 0.11
chr11_102138737_102139426 0.31 RP11-864G5.3
37428
 0.13
chr21_32715523_32716836 0.31 TIAM1
 T-cell lymphoma invasion and metastasis 1
 415
 0.91
chr1_1005420_1005571 0.31 RNF223
 ring finger protein 223
 4192
 0.11
chr22_32079811_32079962 0.30 PISD
 phosphatidylserine decarboxylase
 21468
 0.16
chr15_76442977_76443390 0.30 RP11-593F23.1
30644
 0.19
chr6_24402907_24403844 0.30 MRS2
 MRS2 magnesium transporter
 45
 0.98
chr4_1324444_1324595 0.30 UVSSA
 UV-stimulated scaffold protein A
 16535
 0.12
chr6_166581874_166582172 0.30 T
 T, brachyury homolog (mouse)
 84
 0.98
chr6_42248792_42248943 0.30 MRPS10
 mitochondrial ribosomal protein S10
 63264
 0.1
chr5_9467649_9467848 0.30 CTD-2201E9.2
55542
 0.13
chr11_1783983_1784134 0.30 CTSD
 cathepsin D
 425
 0.53
chr1_110776481_110776632 0.30 KCNC4
 potassium voltage-gated channel, Shaw-related subfamily, member 4
 22434
 0.12
chr3_44040787_44041403 0.29 ENSG00000252980
 .
 71484
 0.12
chr4_62066317_62066605 0.29 LPHN3
 latrophilin 3
 515
 0.89
chr3_197121264_197121415 0.29 ENSG00000238491
 .
 54917
 0.13
chr14_105443453_105443604 0.29 AHNAK2
 AHNAK nucleoprotein 2
 1166
 0.43
chr19_8559121_8559517 0.29 PRAM1
 PML-RARA regulated adaptor molecule 1
 8176
 0.12
chr6_150285486_150285915 0.29 ULBP1
 UL16 binding protein 1
 557
 0.69
chr3_6343229_6343380 0.29 GRM7
 glutamate receptor, metabotropic 7
 468452
 0.01
chr10_99443919_99444098 0.29 AVPI1
 arginine vasopressin-induced 1
 3072
 0.2
chr3_50377359_50378278 0.29 RASSF1
 Ras association (RalGDS/AF-6) domain family member 1
 454
 0.47
chr1_205419612_205419763 0.29 LEMD1
 LEM domain containing 1
 628
 0.66
chr19_626975_627126 0.29 POLRMT
 polymerase (RNA) mitochondrial (DNA directed)
 3118
 0.11
chr8_10587716_10588163 0.29 SOX7
 SRY (sex determining region Y)-box 7
 83
 0.93
chr6_167171492_167171681 0.29 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
 187
 0.97
chr20_23617810_23618640 0.28 CST3
 cystatin C
 357
 0.87
chr17_29887299_29887674 0.28 ENSG00000207614
 .
 471
 0.69
chr14_99713029_99713259 0.28 AL109767.1
16141
 0.21
chr8_145020311_145020609 0.28 PLEC
 plectin
 113
 0.91
chr16_85751517_85751668 0.28 C16orf74
 chromosome 16 open reading frame 74
 7136
 0.13
chr10_125751436_125751814 0.28 CHST15
 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
 54616
 0.13
chr19_11533070_11533503 0.28 RGL3
 ral guanine nucleotide dissociation stimulator-like 3
 3268
 0.1
chr15_99995321_99995472 0.28 MEF2A
 myocyte enhancer factor 2A
 21974
 0.18
chr11_129856033_129856184 0.28 PRDM10
 PR domain containing 10
 16572
 0.23
chr11_125133143_125133294 0.28 RP11-687M24.8
3476
 0.23
chr8_144951231_144951382 0.28 EPPK1
 epiplakin 1
 1326
 0.28
chr12_6485624_6485886 0.28 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
 770
 0.42
chr8_21763339_21763611 0.28 DOK2
 docking protein 2, 56kDa
 7699
 0.2
chr4_25915833_25916134 0.28 SMIM20
 small integral membrane protein 20
 52
 0.98
chr16_15360582_15360733 0.28 NPIPA5
 nuclear pore complex interacting protein family, member A5
 103269
 0.05

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.6 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.4 GO:0001705 ectoderm formation(GO:0001705)
0.1 0.5 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 0.2 GO:0060068 vagina development(GO:0060068)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.3 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 0.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.3 GO:0090009 primitive streak formation(GO:0090009)
0.1 0.2 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.3 GO:0045007 depurination(GO:0045007)
0.1 0.2 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.3 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.2 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.4 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 0.2 GO:0090192 regulation of glomerulus development(GO:0090192)
0.1 0.1 GO:0033483 gas homeostasis(GO:0033483)
0.1 0.2 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.1 0.2 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.1 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.1 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.2 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0090594 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.0 0.2 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.2 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.4 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.3 GO:0007143 female meiotic division(GO:0007143)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.3 GO:0010288 response to lead ion(GO:0010288)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.0 GO:0071503 response to heparin(GO:0071503)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0061162 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0060487 lung epithelial cell differentiation(GO:0060487)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.2 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.3 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0043247 telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.5 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0052308 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.2 GO:0038061 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.0 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0060761 negative regulation of response to cytokine stimulus(GO:0060761)
0.0 0.0 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.1 GO:0032057 negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.0 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0072203 cell proliferation involved in metanephros development(GO:0072203)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0051938 L-glutamate import(GO:0051938)
0.0 0.1 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0032459 regulation of protein oligomerization(GO:0032459)
0.0 0.5 GO:0006821 chloride transport(GO:0006821)
0.0 0.0 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.0 GO:0061054 dermatome development(GO:0061054)
0.0 0.0 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.0 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.0 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.2 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0 0.1 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.0 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.3 GO:0050821 protein stabilization(GO:0050821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032449 CBM complex(GO:0032449)
0.1 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0043197 dendritic spine(GO:0043197)
0.0 0.3 GO:0032155 cell division site(GO:0032153) cell division site part(GO:0032155)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.4 GO:0032407 MutSalpha complex binding(GO:0032407)
0.1 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0035240 dopamine binding(GO:0035240)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.0 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.0 ST ADRENERGIC Adrenergic Pathway
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.1 0.1 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.1 0.1 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME SEMAPHORIN INTERACTIONS Genes involved in Semaphorin interactions
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation