Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TP63

Z-value: 5.89

Motif logo

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Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
ENSG00000073282.8 TP63

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TP63chr3_189511085_18951123635700.3239360.971.8e-05Click!
TP63chr3_189508446_1895085979310.6850930.957.5e-05Click!
TP63chr3_189508774_18950892512590.5766820.933.2e-04Click!
TP63chr3_189231329_1892314801178120.0667170.881.8e-03Click!
TP63chr3_189518135_189518286106200.2554140.872.1e-03Click!

Activity of the TP63 motif across conditions

Conditions sorted by the z-value of the TP63 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_81938636_81938919 2.99 STON2
stonin 2
35968
0.21
chr19_45313552_45313703 2.95 BCAM
basal cell adhesion molecule (Lutheran blood group)
1249
0.33
chr6_161454686_161454957 2.65 MAP3K4
mitogen-activated protein kinase kinase kinase 4
11595
0.25
chr21_36077269_36077677 2.63 CLIC6
chloride intracellular channel 6
35785
0.17
chr3_27391311_27391680 2.58 ENSG00000221573
.
12654
0.2
chr1_145543160_145543350 2.58 RP11-315I20.3

1026
0.34
chr7_134330319_134330562 2.47 BPGM
2,3-bisphosphoglycerate mutase
1120
0.61
chr4_157692546_157692809 2.46 RP11-154F14.2

69834
0.11
chr3_165828020_165828171 2.45 BCHE
butyrylcholinesterase
272835
0.02
chr22_30658056_30658323 2.44 OSM
oncostatin M
3618
0.13
chr19_8559121_8559517 2.32 PRAM1
PML-RARA regulated adaptor molecule 1
8176
0.12
chr11_12029509_12029738 2.30 DKK3
dickkopf WNT signaling pathway inhibitor 3
507
0.87
chr9_129467204_129467355 2.21 ENSG00000266403
.
13333
0.21
chr17_25887386_25887707 2.20 KSR1
kinase suppressor of ras 1
22401
0.19
chr5_44860414_44860565 2.17 MRPS30
mitochondrial ribosomal protein S30
51462
0.16
chr20_23617810_23618640 2.16 CST3
cystatin C
357
0.87
chr1_116381723_116382451 2.15 NHLH2
nescient helix loop helix 2
1275
0.57
chr1_154785958_154786192 2.14 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
46244
0.11
chr10_73769586_73770005 2.12 CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
45672
0.15
chr22_41993578_41993729 2.11 PMM1
phosphomannomutase 1
7759
0.12
chr17_11683304_11683455 2.10 ENSG00000263623
.
38598
0.18
chr4_1760272_1760423 2.09 TACC3
transforming, acidic coiled-coil containing protein 3
30216
0.12
chr3_53303838_53304218 2.07 ENSG00000238565
.
13291
0.12
chr19_3054851_3055002 2.07 AC005944.2

2018
0.21
chr6_27647378_27647849 2.05 ENSG00000238648
.
48425
0.11
chr13_30267815_30267966 2.04 SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
98065
0.08
chr3_52380872_52381023 2.04 DNAH1
dynein, axonemal, heavy chain 1
30612
0.09
chr17_35718321_35718472 2.04 ACACA
acetyl-CoA carboxylase alpha
2337
0.25
chr4_54968164_54968315 2.03 ENSG00000221219
.
1584
0.3
chr3_124913489_124913640 2.00 SLC12A8
solute carrier family 12, member 8
2025
0.37
chr1_174176566_174176717 1.98 ENSG00000238872
.
7273
0.25
chr3_128712029_128712180 1.97 KIAA1257
KIAA1257
815
0.55
chr19_46916092_46916684 1.94 CCDC8
coiled-coil domain containing 8
453
0.75
chr2_42318909_42319060 1.94 PKDCC
protein kinase domain containing, cytoplasmic
43824
0.15
chrX_113309122_113309273 1.93 ENSG00000212611
.
48936
0.16
chr21_40275447_40275732 1.90 ENSG00000272015
.
8880
0.29
chr8_69242814_69243988 1.90 C8orf34
chromosome 8 open reading frame 34
56
0.82
chr1_9953446_9953936 1.90 CTNNBIP1
catenin, beta interacting protein 1
396
0.8
chr3_136676888_136677101 1.88 IL20RB
interleukin 20 receptor beta
143
0.96
chr6_150221787_150221938 1.88 RAET1E
retinoic acid early transcript 1E
2624
0.17
chr19_4866504_4867667 1.87 PLIN3
perilipin 3
39
0.96
chr1_13910269_13910760 1.87 PDPN
podoplanin
74
0.97
chr10_20122027_20122317 1.87 PLXDC2
plexin domain containing 2
17004
0.2
chr15_59586995_59587188 1.86 RP11-429D19.1

23730
0.13
chr3_46420125_46420276 1.85 CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
6039
0.16
chr8_145023500_145024036 1.85 PLEC
plectin
1276
0.29
chr20_15680912_15681288 1.84 ENSG00000212111
.
141987
0.05
chr1_205425664_205426047 1.84 LEMD1
LEM domain containing 1
6796
0.17
chr18_45599789_45599940 1.84 ZBTB7C
zinc finger and BTB domain containing 7C
32370
0.22
chr7_2019823_2019974 1.84 MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
528
0.86
chr7_17094643_17094794 1.83 AGR3
anterior gradient 3
173107
0.03
chr21_43188376_43188583 1.81 RIPK4
receptor-interacting serine-threonine kinase 4
1213
0.47
chr16_29262868_29263019 1.81 RP11-231C14.6

60728
0.09
chr19_18475720_18476136 1.81 PGPEP1
pyroglutamyl-peptidase I
7612
0.09
chr12_258106_258257 1.81 RP11-598F7.4

100
0.96
chr6_119912518_119912669 1.80 MAN1A1
mannosidase, alpha, class 1A, member 1
241667
0.02
chr11_65666484_65666730 1.80 FOSL1
FOS-like antigen 1
1283
0.23
chr8_37350646_37351319 1.80 RP11-150O12.6

23557
0.24
chr9_131865142_131865293 1.79 ENSG00000221521
.
4213
0.12
chrX_49032980_49033201 1.77 PLP2
proteolipid protein 2 (colonic epithelium-enriched)
4817
0.09
chr12_32739224_32739514 1.77 FGD4
FYVE, RhoGEF and PH domain containing 4
12091
0.26
chr20_52726646_52726797 1.76 BCAS1
breast carcinoma amplified sequence 1
39417
0.16
chr17_64911514_64911665 1.75 ENSG00000251764
.
19981
0.17
chr19_1496744_1496895 1.74 REEP6
receptor accessory protein 6
1457
0.17
chr6_89511798_89512012 1.71 ENSG00000222145
.
87756
0.09
chr18_55395208_55395383 1.71 ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
3744
0.22
chr17_43379966_43380348 1.71 ENSG00000199953
.
24706
0.1
chr1_181068882_181069172 1.70 IER5
immediate early response 5
11389
0.23
chr19_47735595_47736220 1.69 BBC3
BCL2 binding component 3
116
0.95
chr7_416332_416483 1.69 AC187652.1
Protein LOC100996433
113489
0.06
chr13_100752699_100753069 1.69 PCCA
propionyl CoA carboxylase, alpha polypeptide
11547
0.27
chr8_96237876_96238027 1.68 C8orf37
chromosome 8 open reading frame 37
43478
0.17
chr10_14116252_14116441 1.68 RP11-397C18.2

63
0.98
chr20_51475685_51475852 1.68 TSHZ2
teashirt zinc finger homeobox 2
113178
0.07
chr21_36173649_36173800 1.68 AP000330.8

55590
0.15
chr5_9467649_9467848 1.68 CTD-2201E9.2

55542
0.13
chr1_118727851_118728117 1.67 SPAG17
sperm associated antigen 17
138
0.98
chr7_100464814_100466140 1.67 TRIP6
thyroid hormone receptor interactor 6
717
0.47
chr9_129263535_129263686 1.67 ENSG00000221768
.
29660
0.17
chr1_61668583_61669016 1.67 RP4-802A10.1

78394
0.11
chr1_3389542_3389693 1.66 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
1429
0.43
chr17_4463313_4463464 1.65 GGT6
gamma-glutamyltransferase 6
158
0.92
chr7_23286622_23287130 1.65 GPNMB
glycoprotein (transmembrane) nmb
482
0.83
chr7_1600012_1600163 1.65 TMEM184A
transmembrane protein 184A
370
0.83
chr12_95071864_95072096 1.64 TMCC3
transmembrane and coiled-coil domain family 3
27642
0.23
chr19_575780_576366 1.64 BSG
basigin (Ok blood group)
852
0.39
chr17_79056077_79056228 1.64 BAIAP2
BAI1-associated protein 2
4109
0.15
chr10_15481466_15481927 1.63 FAM171A1
family with sequence similarity 171, member A1
68635
0.13
chr17_38255735_38256962 1.62 NR1D1
nuclear receptor subfamily 1, group D, member 1
630
0.6
chr2_219159625_219159894 1.62 TMBIM1
transmembrane BAX inhibitor motif containing 1
2450
0.16
chr13_105442959_105443110 1.61 DAOA
D-amino acid oxidase activator
675558
0.0
chr11_8111770_8111921 1.61 TUB
tubby bipartite transcription factor
8936
0.16
chr16_67213263_67213414 1.60 KIAA0895L
KIAA0895-like
627
0.43
chr18_30051729_30051880 1.59 GAREM
GRB2 associated, regulator of MAPK1
1357
0.54
chr8_12989527_12990464 1.59 DLC1
deleted in liver cancer 1
988
0.62
chr6_33558687_33558838 1.58 LINC00336
long intergenic non-protein coding RNA 336
2353
0.2
chr18_28622270_28622475 1.58 DSC3
desmocollin 3
335
0.88
chr16_57654156_57654307 1.58 GPR56
G protein-coupled receptor 56
215
0.92
chr3_151036900_151037051 1.57 GPR87
G protein-coupled receptor 87
2235
0.27
chr9_2156191_2156342 1.57 SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
1414
0.47
chr14_72064432_72064583 1.56 SIPA1L1
signal-induced proliferation-associated 1 like 1
444
0.9
chr6_2104293_2104444 1.55 GMDS
GDP-mannose 4,6-dehydratase
71857
0.13
chr12_93984725_93985802 1.55 SOCS2
suppressor of cytokine signaling 2
16429
0.18
chr6_54564223_54564374 1.54 ENSG00000251946
.
86887
0.1
chr13_51103493_51103911 1.54 ENSG00000221198
.
166329
0.04
chr14_105434423_105434623 1.54 AHNAK2
AHNAK nucleoprotein 2
10171
0.16
chr3_183725112_183725263 1.53 ABCC5-AS1
ABCC5 antisense RNA 1
1061
0.41
chr5_115697040_115697271 1.53 CTB-118N6.3

86088
0.09
chr20_34038560_34038711 1.53 ENSG00000221763
.
3284
0.14
chr14_37050633_37050993 1.52 NKX2-8
NK2 homeobox 8
999
0.51
chr17_46684210_46684361 1.52 HOXB6
homeobox B6
1931
0.13
chr16_74763988_74764262 1.52 FA2H
fatty acid 2-hydroxylase
11042
0.18
chr14_48621220_48621371 1.52 ENSG00000207366
.
189240
0.03
chr20_22370633_22370784 1.52 FOXA2
forkhead box A2
194393
0.03
chr9_139090516_139090790 1.52 LHX3
LIM homeobox 3
4351
0.21
chr1_223492950_223493101 1.52 SUSD4
sushi domain containing 4
43654
0.16
chr15_38543239_38543468 1.52 SPRED1
sprouty-related, EVH1 domain containing 1
1174
0.65
chr1_10703753_10703904 1.51 CASZ1
castor zinc finger 1
1305
0.42
chr20_56265891_56266042 1.51 PMEPA1
prostate transmembrane protein, androgen induced 1
286
0.94
chr2_240008491_240008642 1.50 ENSG00000265416
.
428
0.51
chr8_21960430_21960581 1.50 NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
6405
0.12
chr17_64672504_64672655 1.50 AC006947.1

89
0.97
chr21_44872011_44872162 1.49 SIK1
salt-inducible kinase 1
25078
0.24
chr11_34706995_34707273 1.49 EHF
ets homologous factor
42960
0.19
chr5_2752991_2753357 1.48 C5orf38
chromosome 5 open reading frame 38
795
0.6
chr8_21959623_21959774 1.48 NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
7212
0.11
chr22_50740171_50740441 1.47 PLXNB2
plexin B2
415
0.69
chr5_861665_861816 1.47 ZDHHC11
zinc finger, DHHC-type containing 11
10639
0.17
chr2_238732825_238732976 1.47 RBM44
RNA binding motif protein 44
25079
0.17
chr1_81703498_81704139 1.47 ENSG00000223026
.
13656
0.28
chr1_1005420_1005571 1.46 RNF223
ring finger protein 223
4192
0.11
chr5_73111717_73111868 1.46 ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
2449
0.3
chr5_153903378_153903529 1.46 HAND1
heart and neural crest derivatives expressed 1
45629
0.13
chr8_142235615_142235766 1.46 SLC45A4
solute carrier family 45, member 4
2979
0.21
chr10_75913228_75913379 1.46 ADK
adenosine kinase
2316
0.28
chr6_42248792_42248943 1.46 MRPS10
mitochondrial ribosomal protein S10
63264
0.1
chr18_60458138_60458488 1.45 AC015989.1
Uncharacterized protein
33110
0.16
chr10_21462508_21463481 1.45 NEBL-AS1
NEBL antisense RNA 1
51
0.59
chr16_11296029_11296345 1.44 RMI2
RecQ mediated genome instability 2
47319
0.08
chr3_138635529_138635680 1.43 FOXL2
forkhead box L2
30378
0.16
chr15_70702879_70703030 1.43 ENSG00000200216
.
217379
0.02
chr3_104627662_104627813 1.43 ALCAM
activated leukocyte cell adhesion molecule
458016
0.01
chr2_55227357_55227508 1.42 RTN4
reticulon 4
10153
0.21
chr8_42063953_42065062 1.42 PLAT
plasminogen activator, tissue
576
0.71
chr8_141728080_141728633 1.42 PTK2
protein tyrosine kinase 2
98
0.98
chr3_48636571_48636823 1.42 COL7A1
collagen, type VII, alpha 1
3997
0.11
chr7_5638779_5639073 1.42 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
4609
0.19
chr7_104659627_104659839 1.42 KMT2E
lysine (K)-specific methyltransferase 2E
4825
0.18
chr7_6464271_6464596 1.41 DAGLB
diacylglycerol lipase, beta
23130
0.15
chr1_115214299_115214450 1.41 DENND2C
DENN/MADD domain containing 2C
1642
0.32
chr2_62702703_62702972 1.40 ENSG00000241625
.
15476
0.23
chr2_230138737_230138913 1.40 PID1
phosphotyrosine interaction domain containing 1
2824
0.36
chr19_38491838_38491989 1.40 CTC-244M17.1

37420
0.13
chr17_77023400_77023656 1.40 C1QTNF1-AS1
C1QTNF1 antisense RNA 1
155
0.93
chr1_234793534_234793917 1.40 IRF2BP2
interferon regulatory factor 2 binding protein 2
48454
0.13
chr10_126213488_126213639 1.39 LHPP
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
63151
0.11
chr7_98028694_98029033 1.39 BAIAP2L1
BAI1-associated protein 2-like 1
1517
0.48
chr13_114541163_114541465 1.39 GAS6
growth arrest-specific 6
2297
0.34
chr8_131338301_131338585 1.38 ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
14740
0.29
chr2_161265827_161265978 1.38 RBMS1
RNA binding motif, single stranded interacting protein 1
782
0.57
chr10_99309798_99309949 1.38 ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
22325
0.1
chr3_50194015_50194506 1.37 RP11-493K19.3

742
0.47
chr11_69213982_69214133 1.37 MYEOV
myeloma overexpressed
152432
0.04
chr1_221166154_221166305 1.37 HLX
H2.0-like homeobox
111645
0.06
chr5_82545121_82545472 1.37 XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
171884
0.03
chr7_5468547_5469111 1.37 TNRC18
trinucleotide repeat containing 18
3784
0.17
chr1_8066286_8066437 1.37 ERRFI1
ERBB receptor feedback inhibitor 1
9332
0.19
chr22_46480425_46480827 1.37 FLJ27365
hsa-mir-4763
1257
0.28
chr8_49833429_49833759 1.36 SNAI2
snail family zinc finger 2
394
0.92
chr17_4217041_4217276 1.36 UBE2G1
ubiquitin-conjugating enzyme E2G 1
18060
0.16
chr11_64073389_64074392 1.36 ESRRA
estrogen-related receptor alpha
28
0.92
chr10_88728248_88728709 1.35 ADIRF
adipogenesis regulatory factor
289
0.5
chr10_102773407_102773558 1.35 PDZD7
PDZ domain containing 7
5144
0.11
chr1_61607718_61607869 1.35 RP4-802A10.1

17388
0.23
chr11_94474411_94474676 1.35 RP11-867G2.8

1022
0.6
chr3_129468544_129468695 1.34 TMCC1
transmembrane and coiled-coil domain family 1
44640
0.14
chr6_44030171_44030322 1.34 RP5-1120P11.1

12143
0.17
chr3_151034381_151034532 1.34 GPR87
G protein-coupled receptor 87
284
0.9
chr3_185587401_185587552 1.34 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
44632
0.14
chr15_76442977_76443390 1.34 RP11-593F23.1

30644
0.19
chr8_99235588_99235739 1.33 ENSG00000252558
.
31122
0.18
chr22_39804396_39804547 1.33 TAB1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
8682
0.15
chr1_56106402_56106768 1.33 ENSG00000272051
.
155940
0.04
chr7_20391312_20391720 1.33 CTA-293F17.1

20146
0.18
chr8_17549532_17549683 1.33 MTUS1
microtubule associated tumor suppressor 1
5572
0.18
chr16_82265123_82265274 1.32 ENSG00000251888
.
38803
0.16
chr10_125751436_125751814 1.32 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
54616
0.13
chr19_10120368_10120847 1.32 COL5A3
collagen, type V, alpha 3
540
0.61
chr4_66533944_66534568 1.32 EPHA5
EPH receptor A5
1397
0.61
chr15_86006730_86006881 1.32 ENSG00000251891
.
73690
0.09
chr7_134464463_134465343 1.32 CALD1
caldesmon 1
474
0.89
chr12_91724246_91724397 1.32 DCN
decorin
147421
0.05
chr2_189845775_189845926 1.32 ENSG00000221502
.
3032
0.29
chr1_206687074_206687508 1.32 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
6412
0.15
chr6_24797713_24797864 1.31 C6orf229
chromosome 6 open reading frame 229
1329
0.38
chr11_2824838_2824989 1.31 KCNQ1-AS1
KCNQ1 antisense RNA 1
57885
0.09
chr2_70753382_70753837 1.31 TGFA
transforming growth factor, alpha
27013
0.17
chr10_8077204_8077455 1.30 GATA3
GATA binding protein 3
19327
0.29
chr10_77648848_77649145 1.30 ENSG00000215921
.
65460
0.13
chr2_19226254_19226405 1.30 ENSG00000266738
.
321861
0.01

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.7 2.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.6 1.8 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.5 1.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.5 1.9 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.5 1.5 GO:0060594 mammary gland specification(GO:0060594)
0.4 1.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.4 0.8 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.4 2.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.4 2.5 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.3 1.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.3 1.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 1.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.3 1.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 0.6 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.3 1.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 1.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.3 1.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.3 0.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 0.6 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.3 1.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 1.1 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.3 0.8 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.3 1.7 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.3 0.8 GO:0000966 RNA 5'-end processing(GO:0000966)
0.3 0.8 GO:2000189 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.3 0.8 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.3 0.8 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 0.8 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.3 0.8 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.3 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.3 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 2.6 GO:0031529 ruffle organization(GO:0031529)
0.3 0.8 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.2 0.5 GO:0032632 interleukin-3 production(GO:0032632)
0.2 0.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 0.7 GO:0060068 vagina development(GO:0060068)
0.2 2.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.2 0.7 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.2 0.2 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.2 0.9 GO:0072070 loop of Henle development(GO:0072070)
0.2 1.1 GO:0006828 manganese ion transport(GO:0006828)
0.2 1.1 GO:0001878 response to yeast(GO:0001878)
0.2 1.5 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 0.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.2 0.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 1.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.2 0.6 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.2 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.8 GO:0043276 anoikis(GO:0043276)
0.2 0.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.2 0.2 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.2 0.4 GO:0061162 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.2 1.5 GO:0007172 signal complex assembly(GO:0007172)
0.2 0.8 GO:2000647 negative regulation of stem cell proliferation(GO:2000647)
0.2 0.4 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.2 GO:0001743 optic placode formation(GO:0001743)
0.2 0.2 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 1.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.2 2.1 GO:0046697 decidualization(GO:0046697)
0.2 0.5 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 0.5 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.2 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.5 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.2 0.7 GO:0071800 podosome assembly(GO:0071800)
0.2 0.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.2 0.2 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.2 0.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 0.8 GO:0060023 soft palate development(GO:0060023)
0.2 0.2 GO:0002885 positive regulation of hypersensitivity(GO:0002885)
0.2 0.6 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.3 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2 0.2 GO:0032095 regulation of response to food(GO:0032095) negative regulation of response to food(GO:0032096)
0.2 0.5 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.2 0.5 GO:0022601 menstrual cycle phase(GO:0022601)
0.2 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.1 GO:0009988 cell-cell recognition(GO:0009988)
0.1 0.4 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.8 GO:0001706 endoderm formation(GO:0001706)
0.1 0.1 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.7 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.1 1.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.4 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1 0.3 GO:0061316 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) canonical Wnt signaling pathway involved in heart development(GO:0061316) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.1 0.4 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 1.1 GO:1904377 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.1 0.1 GO:1902305 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.4 GO:0021570 rhombomere 4 development(GO:0021570)
0.1 0.1 GO:0090185 negative regulation of kidney development(GO:0090185)
0.1 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.7 GO:0006949 syncytium formation(GO:0006949)
0.1 0.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.5 GO:0018101 protein citrullination(GO:0018101)
0.1 0.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 0.9 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1 2.5 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.1 1.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.8 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.9 GO:0015884 folic acid transport(GO:0015884)
0.1 0.2 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.7 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.5 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.1 0.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.5 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.1 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1 0.6 GO:0060037 pharyngeal system development(GO:0060037)
0.1 2.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.0 GO:0061515 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.1 0.6 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.1 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1 1.1 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.1 0.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.4 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.1 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 0.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.2 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.2 GO:0090009 primitive streak formation(GO:0090009)
0.1 1.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.1 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.1 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.3 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.2 GO:0009109 coenzyme catabolic process(GO:0009109)
0.1 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.9 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 0.3 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 0.4 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.3 GO:0051955 regulation of amino acid transport(GO:0051955)
0.1 0.5 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.1 0.2 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.1 1.2 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.1 0.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.4 GO:0060134 prepulse inhibition(GO:0060134)
0.1 1.4 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 0.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.7 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.2 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.1 0.2 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.5 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.9 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.1 0.4 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.1 GO:0001963 synaptic transmission, dopaminergic(GO:0001963)
0.1 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.4 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.1 0.2 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.6 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.1 0.1 GO:0048645 organ formation(GO:0048645)
0.1 0.7 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.1 0.5 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.3 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.5 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 1.1 GO:1901222 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 0.2 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.2 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.3 GO:0032222 regulation of synaptic transmission, cholinergic(GO:0032222)
0.1 0.6 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 0.1 GO:0060433 bronchus development(GO:0060433)
0.1 0.2 GO:0018200 peptidyl-glutamic acid modification(GO:0018200)
0.1 0.2 GO:0035850 epithelial cell differentiation involved in kidney development(GO:0035850)
0.1 0.2 GO:0048799 organ maturation(GO:0048799) bone maturation(GO:0070977)
0.1 0.1 GO:0072074 kidney mesenchyme development(GO:0072074) metanephric mesenchyme development(GO:0072075)
0.1 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.2 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.1 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.1 0.1 GO:0001779 natural killer cell differentiation(GO:0001779) regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.2 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1 0.3 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.4 GO:0030916 otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.1 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.3 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.1 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.1 GO:0043552 regulation of phosphatidylinositol 3-kinase activity(GO:0043551) positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.1 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.1 0.2 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.1 0.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.1 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.1 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.6 GO:0032098 regulation of appetite(GO:0032098)
0.1 0.3 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.1 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0048194 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 0.5 GO:0003407 neural retina development(GO:0003407)
0.1 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.2 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.1 0.5 GO:0015074 DNA integration(GO:0015074)
0.1 0.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.1 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.1 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.1 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.5 GO:0009650 UV protection(GO:0009650)
0.1 0.3 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.1 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.1 GO:0007412 axon target recognition(GO:0007412)
0.1 0.2 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.1 GO:0042637 catagen(GO:0042637)
0.1 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0048539 bone marrow development(GO:0048539)
0.1 0.3 GO:0000239 pachytene(GO:0000239)
0.1 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.1 GO:0035872 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.4 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1 0.1 GO:0001705 ectoderm formation(GO:0001705)
0.1 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.3 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 0.2 GO:0009629 response to gravity(GO:0009629)
0.1 0.5 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.2 GO:0017085 response to insecticide(GO:0017085)
0.1 0.1 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.1 0.1 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.1 GO:1903727 positive regulation of phospholipid metabolic process(GO:1903727)
0.1 1.0 GO:0001709 cell fate determination(GO:0001709)
0.1 0.1 GO:0060013 righting reflex(GO:0060013)
0.1 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0002068 glandular epithelial cell development(GO:0002068)
0.1 0.2 GO:0001660 fever generation(GO:0001660)
0.1 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.1 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.1 0.2 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.2 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1 0.1 GO:0046666 programmed cell death involved in cell development(GO:0010623) retinal cell programmed cell death(GO:0046666)
0.1 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:0032094 response to food(GO:0032094)
0.1 0.2 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.1 0.6 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
0.1 0.3 GO:0021915 neural tube development(GO:0021915)
0.1 0.2 GO:0042506 tyrosine phosphorylation of Stat5 protein(GO:0042506)
0.1 0.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.1 GO:0036315 cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.1 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0043954 cellular component maintenance(GO:0043954)
0.0 1.0 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 3.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0007009 plasma membrane organization(GO:0007009)
0.0 0.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.0 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0042634 regulation of hair cycle(GO:0042634)
0.0 0.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:0060444 branching involved in mammary gland duct morphogenesis(GO:0060444)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.1 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.1 GO:0060840 artery development(GO:0060840)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:0030901 midbrain development(GO:0030901)
0.0 0.4 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359)
0.0 0.1 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 0.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0061462 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.9 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.3 GO:1903831 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.1 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.9 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.2 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.0 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 1.0 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.1 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0010889 regulation of sequestering of triglyceride(GO:0010889)
0.0 0.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.3 GO:0007566 embryo implantation(GO:0007566)
0.0 4.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.2 GO:0043526 obsolete neuroprotection(GO:0043526)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.0 GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) metanephric renal vesicle morphogenesis(GO:0072283)
0.0 0.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.1 GO:0021988 olfactory lobe development(GO:0021988)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.3 GO:0007492 endoderm development(GO:0007492)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.0 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.2 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.1 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.3 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.3 GO:0051322 anaphase(GO:0051322)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 1.6 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0016233 telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.2 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 1.1 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.2 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:2000053 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.0 GO:0030826 regulation of cGMP biosynthetic process(GO:0030826)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0048538 thymus development(GO:0048538)
0.0 0.3 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.5 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.6 GO:0030510 regulation of BMP signaling pathway(GO:0030510)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.2 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.5 GO:0035050 embryonic heart tube development(GO:0035050)
0.0 0.2 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.3 GO:0015838 amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0050432 catecholamine secretion(GO:0050432)
0.0 1.0 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.3 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0009265 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.0 0.1 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.3 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.3 GO:0022405 hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) skin epidermis development(GO:0098773)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.2 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.0 0.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.2 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.0 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.3 GO:0007292 female gamete generation(GO:0007292)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 1.5 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.2 GO:0001843 neural tube closure(GO:0001843)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.0 GO:0071295 cellular response to vitamin(GO:0071295)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 2.6 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.7 GO:0017148 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.0 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.5 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.0 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.4 GO:0019079 viral genome replication(GO:0019079)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.5 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:1903008 organelle disassembly(GO:1903008)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0003229 ventricular cardiac muscle tissue development(GO:0003229)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0034661 ncRNA catabolic process(GO:0034661)
0.0 0.1 GO:0072525 pyridine-containing compound biosynthetic process(GO:0072525)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.8 GO:0007338 single fertilization(GO:0007338)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.0 GO:0021675 nerve development(GO:0021675)
0.0 0.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0060073 micturition(GO:0060073)
0.0 0.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.0 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.0 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.2 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.1 GO:0003007 heart morphogenesis(GO:0003007)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.0 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0 0.1 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:0033574 response to testosterone(GO:0033574)
0.0 0.0 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.0 GO:0007143 female meiotic division(GO:0007143)
0.0 0.1 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.0 GO:0048588 developmental cell growth(GO:0048588)
0.0 0.2 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:0072676 lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:0061377 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0051324 prophase(GO:0051324)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.2 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0032652 regulation of interleukin-1 production(GO:0032652)
0.0 0.1 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239)
0.0 0.0 GO:0032341 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342)
0.0 0.1 GO:0009584 detection of visible light(GO:0009584)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0003401 axis elongation(GO:0003401)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0010458 exit from mitosis(GO:0010458)
0.0 0.0 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0032273 positive regulation of protein polymerization(GO:0032273)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 0.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.0 GO:0001964 startle response(GO:0001964)
0.0 0.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.2 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.0 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0060560 developmental growth involved in morphogenesis(GO:0060560)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0032106 positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.0 0.0 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.0 GO:0021782 glial cell development(GO:0021782)
0.0 0.0 GO:0003159 morphogenesis of an endothelium(GO:0003159)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0010669 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.3 7.0 GO:0030057 desmosome(GO:0030057)
0.3 2.3 GO:0031527 filopodium membrane(GO:0031527)
0.3 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.3 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 0.8 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 1.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.8 GO:0070820 tertiary granule(GO:0070820)
0.2 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 1.0 GO:0005915 zonula adherens(GO:0005915)
0.2 0.5 GO:0043259 laminin-10 complex(GO:0043259)
0.2 1.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 3.3 GO:0005811 lipid particle(GO:0005811)
0.2 0.5 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 0.5 GO:0032449 CBM complex(GO:0032449)
0.2 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 0.9 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.7 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.2 GO:0016600 flotillin complex(GO:0016600)
0.1 1.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.1 GO:0030315 T-tubule(GO:0030315)
0.1 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 5.8 GO:0005604 basement membrane(GO:0005604)
0.1 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 8.3 GO:0005925 focal adhesion(GO:0005925)
0.1 1.8 GO:0019861 obsolete flagellum(GO:0019861)
0.1 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 5.9 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.5 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0005861 troponin complex(GO:0005861)
0.1 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.2 GO:0071437 invadopodium(GO:0071437)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0031430 M band(GO:0031430)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.8 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 0.4 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.1 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.1 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.3 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.1 GO:0044447 axoneme part(GO:0044447)
0.1 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.3 GO:0042599 lamellar body(GO:0042599)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0070062 extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 3.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.6 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 11.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.6 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.0 GO:0005924 cell-substrate adherens junction(GO:0005924)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0031674 I band(GO:0031674)
0.0 0.3 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.4 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.5 GO:0019717 obsolete synaptosome(GO:0019717)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.0 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.0 GO:0071565 nBAF complex(GO:0071565)
0.0 8.3 GO:0044421 extracellular region part(GO:0044421)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.4 GO:0030017 sarcomere(GO:0030017)
0.0 0.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 1.2 GO:0030425 dendrite(GO:0030425)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.4 1.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 1.3 GO:0019215 intermediate filament binding(GO:0019215)
0.4 1.5 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.4 1.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.4 1.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 1.4 GO:0048018 receptor agonist activity(GO:0048018)
0.3 2.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 0.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.3 0.3 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 0.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3 1.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.3 1.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 1.5 GO:0043237 laminin-1 binding(GO:0043237)
0.2 0.7 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.2 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 1.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 1.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.2 0.2 GO:0045159 myosin II binding(GO:0045159)
0.2 1.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.4 GO:0017166 vinculin binding(GO:0017166)
0.2 0.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 0.8 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.2 0.4 GO:0016151 nickel cation binding(GO:0016151)
0.2 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.2 0.5 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.2 0.8 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2 0.8 GO:0051400 BH domain binding(GO:0051400)
0.2 0.5 GO:0019863 IgE binding(GO:0019863)
0.2 0.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.2 1.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 0.6 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0009374 biotin binding(GO:0009374)
0.1 0.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 1.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 2.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.5 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.5 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.5 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.5 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.4 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.3 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.0 GO:0043236 laminin binding(GO:0043236)
0.1 0.8 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.0 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.3 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.7 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 3.2 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.3 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.3 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 1.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.6 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.3 GO:0070061 fructose binding(GO:0070061)
0.1 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.1 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.1 GO:0050699 WW domain binding(GO:0050699)
0.1 0.9 GO:0005109 frizzled binding(GO:0005109)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 1.0 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0016595 glutamate binding(GO:0016595)
0.1 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696) BMP receptor binding(GO:0070700)
0.1 0.6 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.2 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0035240 dopamine binding(GO:0035240)
0.1 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 0.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.2 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.2 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.0 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 6.1 GO:0008083 growth factor activity(GO:0008083)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.0 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.9 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.6 GO:0051117 ATPase binding(GO:0051117)
0.0 10.1 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.5 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.0 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.0 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.4 GO:0032934 sterol binding(GO:0032934)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 2.2 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0043178 alcohol binding(GO:0043178)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.0 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 5.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.7 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.2 1.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 1.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 4.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.1 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.1 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.7 PID BMP PATHWAY BMP receptor signaling
0.1 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.1 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 5.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 5.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 4.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.2 2.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 4.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.8 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 0.1 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.4 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 2.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.1 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle