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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TP73

Z-value: 0.73

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Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
TP73
ENSG00000078900.10 TP73

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TP73chr1_3619377_361952848300.1309370.781.3e-02Click!
TP73chr1_3592311_359246265440.1217920.751.9e-02Click!
TP73chr1_3568591_35687424180.5709480.571.1e-01Click!
TP73chr1_3619628_361977950810.1289820.531.4e-01Click!
TP73chr1_3620270_362042157230.1249500.511.6e-01Click!

Activity of the TP73 motif across conditions

Conditions sorted by the z-value of the TP73 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_129846734_129847253 0.20 PTPRE
 protein tyrosine phosphatase, receptor type, E
 1159
 0.62
chr1_27669122_27669371 0.19 SYTL1
 synaptotagmin-like 1
 473
 0.71
chr11_64107928_64108112 0.18 CCDC88B
 coiled-coil domain containing 88B
 325
 0.74
chr17_1000098_1000249 0.17 ABR
 active BCR-related
 12167
 0.2
chr1_26872928_26873171 0.17 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
 706
 0.6
chr17_8869162_8869418 0.16 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 266
 0.94
chr22_39493202_39493353 0.16 APOBEC3H
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
 3
 0.97
chr7_45017320_45017514 0.15 MYO1G
 myosin IG
 1280
 0.35
chr19_1038413_1038573 0.15 AC011558.5
570
 0.49
chr10_135089035_135089208 0.15 ADAM8
 ADAM metallopeptidase domain 8
 1233
 0.29
chr20_47439188_47439680 0.15 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 4986
 0.3
chr7_67474743_67474894 0.14 ENSG00000265600
 .
 653151
 0.0
chr20_62708665_62709256 0.14 RGS19
 regulator of G-protein signaling 19
 1885
 0.17
chr3_195806787_195806938 0.14 TFRC
 transferrin receptor
 2099
 0.29
chr1_26872331_26872899 0.12 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
 272
 0.88
chr17_43301591_43301923 0.12 CTD-2020K17.1
2168
 0.16
chr19_13207805_13208124 0.12 LYL1
 lymphoblastic leukemia derived sequence 1
 5717
 0.11
chr17_3818740_3818909 0.12 P2RX1
 purinergic receptor P2X, ligand-gated ion channel, 1
 970
 0.51
chr22_46684122_46684292 0.12 GTSE1
 G-2 and S-phase expressed 1
 8431
 0.15
chr7_50351468_50351619 0.11 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 3225
 0.36
chr12_122250872_122251023 0.11 SETD1B
 SET domain containing 1B
 8309
 0.15
chr20_826966_827117 0.11 FAM110A
 family with sequence similarity 110, member A
 1274
 0.53
chr10_73847489_73847640 0.11 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 522
 0.83
chr10_135073019_135073240 0.11 MIR202HG
 MIR202 host gene (non-protein coding)
 11734
 0.1
chr10_49894087_49894238 0.11 WDFY4
 WDFY family member 4
 1241
 0.52
chr19_5804658_5804817 0.11 DUS3L
 dihydrouridine synthase 3-like (S. cerevisiae)
 13488
 0.08
chr12_9912735_9912912 0.11 CD69
 CD69 molecule
 674
 0.66
chr7_1551351_1551591 0.11 AC102953.6
2408
 0.22
chr22_30768667_30768959 0.11 RP1-130H16.16
5049
 0.09
chr6_42013197_42013548 0.11 CCND3
 cyclin D3
 3052
 0.21
chr19_3136242_3137376 0.11 GNA15
 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
 618
 0.58
chr17_40441173_40441395 0.11 STAT5A
 signal transducer and activator of transcription 5A
 723
 0.54
chr22_50747133_50747284 0.11 PLXNB2
 plexin B2
 1152
 0.29
chr7_45016674_45016991 0.10 MYO1G
 myosin IG
 1865
 0.25
chr9_139000986_139001191 0.10 C9orf69
 chromosome 9 open reading frame 69
 9032
 0.19
chr19_12776607_12776758 0.10 MAN2B1
 mannosidase, alpha, class 2B, member 1
 866
 0.26
chrX_57313067_57313960 0.10 FAAH2
 fatty acid amide hydrolase 2
 374
 0.92
chr4_9154561_9154798 0.10 ENSG00000264372
 .
 15341
 0.12
chr16_4714977_4715231 0.10 MGRN1
 mahogunin ring finger 1, E3 ubiquitin protein ligase
 14703
 0.11
chr10_74080255_74080406 0.10 DNAJB12
 DnaJ (Hsp40) homolog, subfamily B, member 12
 24389
 0.15
chr1_42192309_42192460 0.10 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 25712
 0.21
chr19_54677285_54677436 0.10 TMC4
 transmembrane channel-like 4
 416
 0.64
chr17_73567230_73567381 0.10 MYO15B
 myosin XVB pseudogene
 19553
 0.1
chr5_34930297_34930570 0.10 DNAJC21
 DnaJ (Hsp40) homolog, subfamily C, member 21
 735
 0.64
chr14_103577704_103577855 0.10 EXOC3L4
 exocyst complex component 3-like 4
 3926
 0.19
chr19_52132963_52133123 0.10 SIGLEC5
 sialic acid binding Ig-like lectin 5
 545
 0.64
chr15_40532500_40532651 0.10 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
 148
 0.93
chr15_83348879_83349094 0.10 AP3B2
 adaptor-related protein complex 3, beta 2 subunit
 19006
 0.12
chr14_91839274_91839753 0.10 ENSG00000265856
 .
 39456
 0.15
chr1_6085866_6086187 0.10 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
 334
 0.88
chrX_106033404_106033689 0.10 TBC1D8B
 TBC1 domain family, member 8B (with GRAM domain)
 12364
 0.24
chr19_42926797_42927063 0.09 LIPE
 lipase, hormone-sensitive
 425
 0.63
chr5_176785668_176785889 0.09 RGS14
 regulator of G-protein signaling 14
 940
 0.38
chr19_2041550_2041783 0.09 MKNK2
 MAP kinase interacting serine/threonine kinase 2
 415
 0.72
chr19_3179462_3180177 0.09 S1PR4
 sphingosine-1-phosphate receptor 4
 1083
 0.38
chr17_76165715_76165934 0.09 SYNGR2
 synaptogyrin 2
 585
 0.61
chr9_92096324_92096488 0.09 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 1601
 0.45
chr17_55339641_55339792 0.09 MSI2
 musashi RNA-binding protein 2
 5337
 0.3
chr17_56355369_56355598 0.09 MPO
 myeloperoxidase
 2813
 0.18
chr14_91731332_91731581 0.09 GPR68
 G protein-coupled receptor 68
 11187
 0.16
chr3_184098891_184099179 0.09 CHRD
 chordin
 928
 0.39
chrX_38922731_38922882 0.09 ENSG00000207122
 .
 17732
 0.3
chr17_1548323_1548533 0.09 SCARF1
 scavenger receptor class F, member 1
 610
 0.56
chr9_116343099_116343250 0.09 RGS3
 regulator of G-protein signaling 3
 34
 0.98
chr1_6090319_6090470 0.09 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
 3037
 0.23
chr12_113494960_113495179 0.09 DTX1
 deltex homolog 1 (Drosophila)
 426
 0.82
chr7_45067326_45068016 0.09 CCM2
 cerebral cavernous malformation 2
 400
 0.81
chr18_72783416_72783729 0.09 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
 133896
 0.05
chr6_35270906_35271095 0.09 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 5371
 0.2
chr20_58632411_58632562 0.09 C20orf197
 chromosome 20 open reading frame 197
 1506
 0.49
chr11_74699974_74700511 0.09 NEU3
 sialidase 3 (membrane sialidase)
 252
 0.9
chr19_16696203_16696354 0.09 MED26
 mediator complex subunit 26
 2134
 0.15
chr16_85605071_85605483 0.09 GSE1
 Gse1 coiled-coil protein
 39738
 0.16
chr7_63361181_63361806 0.09 ENSG00000263891
 .
 47
 0.98
chr19_49977449_49977689 0.09 FLT3LG
 fms-related tyrosine kinase 3 ligand
 60
 0.9
chr9_34591301_34591802 0.09 CNTFR
 ciliary neurotrophic factor receptor
 1430
 0.24
chr9_95822109_95822464 0.09 SUSD3
 sushi domain containing 3
 1225
 0.45
chr10_81077160_81077479 0.09 ZMIZ1
 zinc finger, MIZ-type containing 1
 11344
 0.22
chr1_17026830_17027051 0.09 ESPNP
 espin pseudogene
 10174
 0.12
chr1_40426265_40426496 0.09 MFSD2A
 major facilitator superfamily domain containing 2A
 5558
 0.17
chr8_103674687_103674993 0.09 KLF10
 Kruppel-like factor 10
 6710
 0.25
chr1_110158969_110159120 0.09 AMPD2
 adenosine monophosphate deaminase 2
 318
 0.77
chr3_32502059_32502315 0.09 CMTM6
 CKLF-like MARVEL transmembrane domain containing 6
 42713
 0.15
chr19_52149205_52149440 0.09 SIGLEC5
 sialic acid binding Ig-like lectin 5
 524
 0.49
chrX_78621891_78622920 0.08 ITM2A
 integral membrane protein 2A
 451
 0.91
chr19_1840880_1841031 0.08 REXO1
 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
 7497
 0.08
chr2_242801310_242801461 0.08 PDCD1
 programmed cell death 1
 325
 0.81
chr1_175160611_175161799 0.08 KIAA0040
 KIAA0040
 685
 0.78
chr21_43639797_43640496 0.08 ABCG1
 ATP-binding cassette, sub-family G (WHITE), member 1
 215
 0.89
chr1_41131794_41131945 0.08 RIMS3
 regulating synaptic membrane exocytosis 3
 540
 0.74
chr15_90754552_90754703 0.08 SEMA4B
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
 9859
 0.12
chr22_37639373_37639682 0.08 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
 761
 0.58
chr17_46688443_46688779 0.08 HOXB7
 homeobox B7
 232
 0.8
chr22_37639776_37640249 0.08 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
 276
 0.88
chrX_142723045_142723196 0.08 SLITRK4
 SLIT and NTRK-like family, member 4
 101
 0.98
chr2_235165280_235165431 0.08 SPP2
 secreted phosphoprotein 2, 24kDa
 205924
 0.02
chr1_28196256_28196434 0.08 THEMIS2
 thymocyte selection associated family member 2
 2710
 0.16
chr11_63974616_63975431 0.08 FERMT3
 fermitin family member 3
 266
 0.78
chr19_13206173_13206324 0.08 LYL1
 lymphoblastic leukemia derived sequence 1
 7433
 0.1
chrX_117662084_117662235 0.08 DOCK11
 dedicator of cytokinesis 11
 32287
 0.18
chr22_37881004_37881696 0.08 MFNG
 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 683
 0.62
chr10_5334923_5335219 0.08 AKR1C7P
 aldo-keto reductase family 1, member C7, pseudogene
 4638
 0.23
chr3_129830565_129830801 0.08 FAM86HP
 family with sequence similarity 86, member H, pseudogene
 368
 0.85
chr2_145198575_145198734 0.08 ZEB2
 zinc finger E-box binding homeobox 2
 10517
 0.28
chr2_113593127_113593420 0.08 IL1B
 interleukin 1, beta
 738
 0.63
chr17_4847711_4848500 0.08 RNF167
 ring finger protein 167
 1959
 0.11
chr3_52265762_52265913 0.08 TLR9
 TLR9
 631
 0.53
chr15_81590554_81590826 0.08 IL16
 interleukin 16
 1067
 0.54
chr3_5028227_5029021 0.08 BHLHE40-AS1
 BHLHE40 antisense RNA 1
 6978
 0.21
chr9_74398314_74398465 0.08 TMEM2
 transmembrane protein 2
 14589
 0.27
chr20_31099035_31099434 0.08 C20orf112
 chromosome 20 open reading frame 112
 24
 0.98
chr17_35078057_35078719 0.08 MRM1
 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
 119997
 0.04
chr5_76146227_76146557 0.08 S100Z
 S100 calcium binding protein Z
 468
 0.79
chr16_390161_390342 0.08 AXIN1
 axin 1
 12198
 0.1
chr11_67121279_67121678 0.08 POLD4
 polymerase (DNA-directed), delta 4, accessory subunit
 461
 0.64
chr11_72493009_72493423 0.08 STARD10
 StAR-related lipid transfer (START) domain containing 10
 188
 0.89
chr5_131757138_131757303 0.08 AC116366.5
4926
 0.14
chr6_149805124_149805364 0.08 ZC3H12D
 zinc finger CCCH-type containing 12D
 882
 0.55
chr9_215390_215630 0.08 DOCK8
 dedicator of cytokinesis 8
 339
 0.52
chr11_103947079_103947230 0.07 PDGFD
 platelet derived growth factor D
 39400
 0.18
chr11_65307798_65308115 0.07 LTBP3
 latent transforming growth factor beta binding protein 3
 33
 0.95
chr8_135700072_135700223 0.07 ZFAT
 zinc finger and AT hook domain containing
 8650
 0.29
chr9_129485287_129485658 0.07 ENSG00000266403
 .
 4860
 0.26
chr12_133070120_133070271 0.07 FBRSL1
 fibrosin-like 1
 3038
 0.27
chr22_38576947_38577679 0.07 PLA2G6
 phospholipase A2, group VI (cytosolic, calcium-independent)
 448
 0.76
chr11_44613932_44614083 0.07 CD82
 CD82 molecule
 4399
 0.23
chr20_62199468_62200014 0.07 HELZ2
 helicase with zinc finger 2, transcriptional coactivator
 314
 0.8
chr14_103578008_103578159 0.07 EXOC3L4
 exocyst complex component 3-like 4
 4230
 0.19
chr6_166954866_166955076 0.07 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
 967
 0.56
chr7_5595689_5595960 0.07 CTB-161C1.1
538
 0.69
chr10_74079018_74079438 0.07 DNAJB12
 DnaJ (Hsp40) homolog, subfamily B, member 12
 25491
 0.15
chr1_21978657_21978808 0.07 RAP1GAP
 RAP1 GTPase activating protein
 384
 0.87
chr17_34128388_34128539 0.07 MMP28
 matrix metallopeptidase 28
 5752
 0.1
chr7_30517944_30518357 0.07 NOD1
 nucleotide-binding oligomerization domain containing 1
 102
 0.97
chr3_50267688_50267839 0.07 GNAI2
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
 4039
 0.13
chr10_70982290_70982511 0.07 HKDC1
 hexokinase domain containing 1
 2341
 0.24
chr19_36233477_36233815 0.07 IGFLR1
 IGF-like family receptor 1
 292
 0.71
chr7_155386209_155386360 0.07 AC009403.2
 Protein LOC100506302
 50811
 0.12
chr11_67917703_67917854 0.07 CTD-2655K5.1
20513
 0.14
chr19_3145852_3146003 0.07 AC005264.2
9246
 0.11
chr4_15004964_15005278 0.07 CPEB2
 cytoplasmic polyadenylation element binding protein 2
 401
 0.91
chr3_52140725_52140876 0.07 LINC00696
 long intergenic non-protein coding RNA 696
 43233
 0.09
chr19_43857990_43858141 0.07 CD177
 CD177 molecule
 240
 0.92
chr2_7059033_7059408 0.07 ENSG00000228203
 .
 380
 0.82
chr17_66340892_66341141 0.07 ARSG
 arylsulfatase G
 53357
 0.11
chr9_137235953_137236130 0.07 RXRA
 retinoid X receptor, alpha
 17615
 0.22
chr11_67045241_67045509 0.07 ANKRD13D
 ankyrin repeat domain 13 family, member D
 10643
 0.11
chr19_35985015_35985166 0.07 KRTDAP
 keratinocyte differentiation-associated protein
 3657
 0.13
chr5_1105065_1105874 0.07 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 6681
 0.19
chr15_31653239_31653495 0.07 KLF13
 Kruppel-like factor 13
 4990
 0.34
chr19_55836444_55836628 0.07 TMEM150B
 transmembrane protein 150B
 133
 0.89
chr3_15482302_15482608 0.07 EAF1-AS1
 EAF1 antisense RNA 1
 354
 0.48
chr14_70161423_70161574 0.07 SRSF5
 serine/arginine-rich splicing factor 5
 32119
 0.19
chr19_38539302_38539460 0.07 ENSG00000221258
 .
 5224
 0.2
chr15_40627878_40628029 0.07 C15orf52
 chromosome 15 open reading frame 52
 2288
 0.13
chr20_58803254_58803405 0.07 ENSG00000207802
 .
 80203
 0.11
chr10_45958891_45959042 0.07 RP11-67C2.2
10397
 0.25
chr17_29645805_29646348 0.07 CTD-2370N5.3
227
 0.88
chr18_13465441_13465744 0.07 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 578
 0.59
chr20_52195598_52195985 0.07 ZNF217
 zinc finger protein 217
 3225
 0.23
chr7_98871889_98872040 0.07 ARPC1A
 actin related protein 2/3 complex, subunit 1A, 41kDa
 51557
 0.11
chr2_221889944_221890095 0.07 EPHA4
 EPH receptor A4
 477261
 0.01
chr22_39885842_39885993 0.07 MIEF1
 mitochondrial elongation factor 1
 10188
 0.13
chr12_53718111_53718485 0.07 AAAS
 achalasia, adrenocortical insufficiency, alacrimia
 244
 0.86
chr13_41553204_41553401 0.07 ELF1
 E74-like factor 1 (ets domain transcription factor)
 3116
 0.27
chr1_92949289_92949440 0.07 GFI1
 growth factor independent 1 transcription repressor
 147
 0.97
chr1_209943004_209943387 0.07 TRAF3IP3
 TRAF3 interacting protein 3
 1235
 0.37
chr9_139923753_139923935 0.07 ABCA2
 ATP-binding cassette, sub-family A (ABC1), member 2
 1104
 0.19
chr4_2789531_2789742 0.07 SH3BP2
 SH3-domain binding protein 2
 5114
 0.22
chr3_186598535_186598686 0.07 ADIPOQ-AS1
 ADIPOQ antisense RNA 1
 24698
 0.12
chr19_12660200_12660351 0.06 ZNF564
 zinc finger protein 564
 1973
 0.19
chr11_57333961_57334391 0.06 UBE2L6
 ubiquitin-conjugating enzyme E2L 6
 600
 0.6
chr9_95895594_95896005 0.06 NINJ1
 ninjurin 1
 771
 0.63
chr1_15279622_15279773 0.06 KAZN
 kazrin, periplakin interacting protein
 7282
 0.31
chr8_12294063_12294275 0.06 FAM86B2
 family with sequence similarity 86, member B2
 254
 0.93
chr16_11722953_11723104 0.06 LITAF
 lipopolysaccharide-induced TNF factor
 38
 0.98
chr11_68596728_68596879 0.06 CPT1A
 carnitine palmitoyltransferase 1A (liver)
 10349
 0.2
chr16_89427646_89427797 0.06 ANKRD11
 ankyrin repeat domain 11
 32327
 0.11
chr19_18113119_18113338 0.06 ARRDC2
 arrestin domain containing 2
 1287
 0.37
chr10_5295585_5295741 0.06 AKR1C7P
 aldo-keto reductase family 1, member C7, pseudogene
 34770
 0.13
chr12_132899931_132900082 0.06 GALNT9
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
 5783
 0.19
chr16_55533839_55533990 0.06 LPCAT2
 lysophosphatidylcholine acyltransferase 2
 8996
 0.21
chr9_135937365_135937516 0.06 CEL
 carboxyl ester lipase
 75
 0.96
chr6_10643337_10643488 0.06 GCNT6
 glucosaminyl (N-acetyl) transferase 6
 9254
 0.15
chr19_16358640_16358791 0.06 AP1M1
 adaptor-related protein complex 1, mu 1 subunit
 20299
 0.14
chr18_28681584_28682412 0.06 DSC2
 desmocollin 2
 31
 0.88
chr8_144634447_144634598 0.06 GSDMD
 gasdermin D
 855
 0.33
chr11_73358513_73358664 0.06 PLEKHB1
 pleckstrin homology domain containing, family B (evectins) member 1
 6
 0.98
chr14_104048722_104048873 0.06 ENSG00000264904
 .
 6401
 0.09
chr18_23670660_23670942 0.06 SS18
 synovial sarcoma translocation, chromosome 18
 64
 0.98
chr10_73516963_73517263 0.06 C10orf54
 chromosome 10 open reading frame 54
 274
 0.92
chr10_50395214_50395459 0.06 C10orf128
 chromosome 10 open reading frame 128
 1021
 0.55
chr6_43766546_43766697 0.06 VEGFA
 vascular endothelial growth factor A
 24531
 0.16
chr16_89790012_89790261 0.06 ZNF276
 zinc finger protein 276
 2184
 0.16
chr15_34875013_34876331 0.06 GOLGA8B
 golgin A8 family, member B
 99
 0.96
chr5_42991474_42991625 0.06 CTD-2035E11.3
26982
 0.15
chr16_27328627_27328778 0.06 IL4R
 interleukin 4 receptor
 3389
 0.25
chr3_184081214_184081580 0.06 POLR2H
 polymerase (RNA) II (DNA directed) polypeptide H
 175
 0.89
chr2_30372277_30372798 0.06 YPEL5
 yippee-like 5 (Drosophila)
 2155
 0.3
chr8_66922647_66922798 0.06 DNAJC5B
 DnaJ (Hsp40) homolog, subfamily C, member 5 beta
 11073
 0.28

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TP73

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0035067 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling