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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for VAX2_RHOXF2

Z-value: 1.15

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Transcription factors associated with VAX2_RHOXF2

Gene Symbol	Gene ID	Gene Info
VAX2 Ensembl NCBI GeneCards UniProt	ENSG00000116035.2	ventral anterior homeobox 2
RHOXF2 Ensembl NCBI GeneCards UniProt	ENSG00000131721.4	Rhox homeobox family member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chrX_119278155_119278306	RHOXF2	14237	0.163265	-0.60	9.1e-02	Click!
chrX_119278328_119278479	RHOXF2	14064	0.163740	-0.51	1.7e-01	Click!
chr2_71114371_71114522	VAX2	13274	0.124044	0.82	7.1e-03	Click!
chr2_71126740_71126891	VAX2	905	0.463758	-0.72	2.8e-02	Click!
chr2_71098893_71099044	VAX2	28752	0.104996	-0.69	4.0e-02	Click!
chr2_71128415_71128566	VAX2	770	0.527946	-0.69	4.1e-02	Click!
chr2_71128631_71128867	VAX2	1029	0.409447	-0.65	5.9e-02	Click!

Activity of the VAX2_RHOXF2 motif across conditions

Conditions sorted by the z-value of the VAX2_RHOXF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_108543496_108543820	1.65	TRAT1	T cell receptor associated transmembrane adaptor 1	2039	0.42
chr1_51442241_51442392	1.17	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	6700	0.22
chr7_26141262_26141558	1.11	ENSG00000266430	.	41451	0.15
chr9_117721707_117721858	1.11	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	29085	0.23
chr13_31309966_31310295	1.09	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	485	0.88
chr2_38894094_38894271	1.08	GALM	galactose mutarotase (aldose 1-epimerase)	923	0.55
chr14_71454929_71455080	1.03	PCNX	pecanex homolog (Drosophila)	24744	0.26
chr1_92269176_92269391	1.01	ENSG00000239794	.	26348	0.22
chr6_26198173_26198564	1.01	HIST1H3D	histone cluster 1, H3d	890	0.22
chr21_25260128_25260279	0.97	ENSG00000199698	.	455601	0.01
chr13_99957828_99957979	0.96	GPR183	G protein-coupled receptor 183	1756	0.38
chr11_122597673_122598179	0.96	ENSG00000239079	.	907	0.67
chr7_50348449_50348781	0.91	IKZF1	IKAROS family zinc finger 1 (Ikaros)	297	0.94
chr4_25865391_25865542	0.91	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)	84	0.98
chrX_19815653_19816006	0.90	SH3KBP1	SH3-domain kinase binding protein 1	2040	0.46
chr1_226251298_226251924	0.89	H3F3A	H3 histone, family 3A	67	0.97
chr5_65014979_65015130	0.88	SGTB	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta	2903	0.24
chr5_44684027_44684178	0.87	ENSG00000263556	.	32190	0.23
chr20_18446613_18446764	0.83	DZANK1	double zinc ribbon and ankyrin repeat domains 1	663	0.48
chr7_23571303_23571524	0.82	TRA2A	transformer 2 alpha homolog (Drosophila)	182	0.95
chr10_63999686_63999837	0.76	RTKN2	rhotekin 2	3739	0.34
chr17_75955874_75956555	0.76	ENSG00000238898	.	40034	0.14
chr15_87678295_87678446	0.75	RP11-133L19.1		146713	0.05
chr7_21472009_21472160	0.74	SP4	Sp4 transcription factor	4423	0.22
chr13_33608099_33608250	0.73	ENSG00000221677	.	7315	0.24
chr17_47766049_47766200	0.72	SPOP	speckle-type POZ protein	10528	0.14
chr5_130882612_130883040	0.71	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	14100	0.29
chr3_56949638_56949992	0.71	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	684	0.75
chr5_110560941_110561277	0.69	CAMK4	calcium/calmodulin-dependent protein kinase IV	1325	0.51
chrX_21676681_21677086	0.69	KLHL34	kelch-like family member 34	435	0.89
chr17_37774592_37774840	0.67	PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	8277	0.12
chrX_154298671_154299361	0.67	MTCP1	mature T-cell proliferation 1	485	0.41
chr18_67623845_67624178	0.66	CD226	CD226 molecule	105	0.98
chr21_32532372_32532523	0.66	TIAM1	T-cell lymphoma invasion and metastasis 1	29908	0.23
chr4_2486639_2486842	0.66	RNF4	ring finger protein 4	4798	0.2
chr2_175458036_175458370	0.65	WIPF1	WAS/WASL interacting protein family, member 1	4290	0.21
chr10_47640402_47640757	0.65	ANTXRLP1	anthrax toxin receptor-like pseudogene 1	4212	0.25
chr10_6627562_6627792	0.64	PRKCQ	protein kinase C, theta	5414	0.34
chr5_106819740_106819891	0.64	EFNA5	ephrin-A5	186513	0.03
chr13_41555714_41555943	0.63	ELF1	E74-like factor 1 (ets domain transcription factor)	590	0.77
chr5_118606885_118607036	0.63	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2511	0.28
chr5_67577391_67577649	0.62	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	1385	0.58
chr1_234544831_234544982	0.62	COA6	cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)	35459	0.12
chrX_31453419_31453570	0.62	ENSG00000252903	.	87185	0.1
chr5_118653769_118653920	0.61	ENSG00000243333	.	11518	0.19
chr14_55031464_55032039	0.60	SAMD4A	sterile alpha motif domain containing 4A	2064	0.37
chr7_106507057_106507208	0.60	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	1208	0.59
chr3_20050398_20050549	0.60	PP2D1	protein phosphatase 2C-like domain containing 1	3349	0.22
chr14_32672268_32672419	0.60	ENSG00000202337	.	132	0.94
chr14_88471433_88472132	0.60	GPR65	G protein-coupled receptor 65	314	0.88
chr1_227501319_227501470	0.59	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	3489	0.36
chr3_108549304_108549455	0.59	TRAT1	T cell receptor associated transmembrane adaptor 1	7760	0.27
chr18_32180370_32180521	0.57	DTNA	dystrobrevin, alpha	7116	0.32
chr1_111212136_111212287	0.57	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	5444	0.2
chr9_80524074_80524374	0.57	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	86309	0.1
chr11_88087417_88087693	0.56	CTSC	cathepsin C	16600	0.28
chr22_31317515_31317990	0.56	MORC2-AS1	MORC2 antisense RNA 1	543	0.73
chr21_32555155_32555306	0.56	TIAM1	T-cell lymphoma invasion and metastasis 1	52691	0.16
chr2_88124610_88124761	0.55	RGPD2	RANBP2-like and GRIP domain containing 2	601	0.82
chr6_30477261_30477412	0.55	XXbac-BPG249D20.9		6707	0.13
chr20_2273286_2273437	0.55	TGM3	transglutaminase 3	3286	0.31
chr2_202987834_202988283	0.55	AC079354.3		6277	0.17
chr11_130304615_130304994	0.55	ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8	5916	0.25
chr1_2161918_2162386	0.54	SKI	v-ski avian sarcoma viral oncogene homolog	2018	0.23
chrX_118818753_118818904	0.54	SEPT6	septin 6	7964	0.18
chr6_41855450_41855601	0.54	USP49	ubiquitin specific peptidase 49	458	0.75
chr12_58335952_58336152	0.54	XRCC6BP1	XRCC6 binding protein 1	692	0.67
chr19_50062782_50062933	0.54	NOSIP	nitric oxide synthase interacting protein	1030	0.27
chr13_49065751_49065929	0.54	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	41373	0.17
chr2_2650168_2650319	0.53	MYT1L	myelin transcription factor 1-like	315277	0.01
chr5_75600050_75600201	0.53	RP11-466P24.6		7162	0.3
chr4_39032194_39032374	0.53	TMEM156	transmembrane protein 156	1757	0.38
chr1_27026544_27026953	0.53	ARID1A	AT rich interactive domain 1A (SWI-like)	3853	0.18
chr1_65096460_65096611	0.53	ENSG00000264470	.	51005	0.17
chr19_12888779_12888973	0.53	HOOK2	hook microtubule-tethering protein 2	350	0.68
chr15_44101218_44101369	0.53	HYPK	huntingtin interacting protein K	8496	0.08
chr5_130881277_130881428	0.52	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	12626	0.29
chr17_78755045_78755196	0.52	RP11-28G8.1		24312	0.21
chr4_154411300_154411567	0.52	KIAA0922	KIAA0922	23932	0.22
chr8_27131821_27132033	0.52	STMN4	stathmin-like 4	15990	0.18
chr5_171611525_171611676	0.52	STK10	serine/threonine kinase 10	3790	0.23
chr19_46088302_46088477	0.51	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)	289	0.84
chr1_90097236_90097387	0.51	RP5-1007M22.2		439	0.72
chrX_129305086_129305298	0.51	RAB33A	RAB33A, member RAS oncogene family	431	0.84
chr7_99697639_99698087	0.51	MCM7	minichromosome maintenance complex component 7	517	0.45
chr4_151934623_151934774	0.51	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	1721	0.4
chr1_45284842_45285269	0.51	ENSG00000202444	.	614	0.49
chrX_47880068_47880219	0.51	SPACA5	sperm acrosome associated 5	12949	0.14
chr5_140457403_140457554	0.50	PCDHB2	protocadherin beta 2	16749	0.09
chr9_20242645_20242902	0.50	ENSG00000221744	.	52229	0.16
chrX_28529887_28530038	0.50	IL1RAPL1	interleukin 1 receptor accessory protein-like 1	75554	0.12
chr15_64767992_64768143	0.50	RP11-702L15.4		5615	0.15
chr11_58777091_58777242	0.50	RP11-142C4.6		30408	0.16
chr8_1427567_1427718	0.49	DLGAP2	discs, large (Drosophila) homolog-associated protein 2	21890	0.27
chr1_113164228_113164419	0.49	ST7L	suppression of tumorigenicity 7 like	2283	0.19
chr5_81762775_81762926	0.48	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	161684	0.04
chr8_103425274_103425485	0.48	UBR5	ubiquitin protein ligase E3 component n-recognin 5	310	0.89
chr11_104915569_104916017	0.48	CARD16	caspase recruitment domain family, member 16	241	0.92
chr16_33332405_33332556	0.48	RP11-23E10.4		40922	0.16
chr10_70850849_70851349	0.47	SRGN	serglycin	3225	0.25
chr14_77873229_77873401	0.47	FKSG61		9426	0.11
chr6_135518404_135518725	0.46	MYB-AS1	MYB antisense RNA 1	1431	0.4
chr8_39797291_39797650	0.46	IDO2	indoleamine 2,3-dioxygenase 2	4996	0.18
chr14_22747289_22747440	0.46	ENSG00000238634	.	136477	0.04
chr5_73243724_73243875	0.46	ARHGEF28	Rho guanine nucleotide exchange factor (GEF) 28	62071	0.14
chr9_113318580_113318731	0.46	ENSG00000212254	.	16577	0.22
chr12_14538429_14538715	0.46	ATF7IP	activating transcription factor 7 interacting protein	574	0.82
chr12_27472599_27472750	0.46	ARNTL2	aryl hydrocarbon receptor nuclear translocator-like 2	13113	0.22
chr17_32709853_32710004	0.46	CCL1	chemokine (C-C motif) ligand 1	19678	0.17
chr2_198080893_198081173	0.46	ANKRD44	ankyrin repeat domain 44	18271	0.19
chr19_42390602_42391041	0.45	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	2306	0.19
chr16_22020806_22020957	0.45	C16orf52	chromosome 16 open reading frame 52	1277	0.42
chr7_105515013_105515164	0.45	ATXN7L1	ataxin 7-like 1	1835	0.48
chr10_51500864_51501147	0.45	AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	14678	0.19
chr7_38400564_38400715	0.45	AMPH	amphiphysin	102074	0.08
chr3_183852600_183853095	0.45	RP11-778D9.12		122	0.61
chr21_16726840_16726991	0.44	ENSG00000212564	.	259687	0.02
chr2_224822174_224823087	0.44	MRPL44	mitochondrial ribosomal protein L44	509	0.78
chr8_113941673_113941824	0.44	CSMD3	CUB and Sushi multiple domains 3	239477	0.02
chr6_159464766_159465080	0.44	TAGAP	T-cell activation RhoGTPase activating protein	1127	0.51
chr20_8349746_8349924	0.44	PLCB1-IT1	PLCB1 intronic transcript 1 (non-protein coding)	120463	0.06
chrX_78403286_78403508	0.44	GPR174	G protein-coupled receptor 174	23072	0.28
chr6_30797258_30797409	0.43	ENSG00000202241	.	34694	0.07
chrX_78400540_78401325	0.43	GPR174	G protein-coupled receptor 174	25537	0.27
chr5_73982840_73982991	0.43	HEXB	hexosaminidase B (beta polypeptide)	1946	0.34
chr3_32998333_32998484	0.43	CCR4	chemokine (C-C motif) receptor 4	5342	0.28
chr1_66806017_66806168	0.43	PDE4B	phosphodiesterase 4B, cAMP-specific	8220	0.31
chrX_135732358_135732618	0.43	CD40LG	CD40 ligand	2102	0.29
chr3_95425254_95425405	0.43	ENSG00000221477	.	460417	0.01
chr11_85427844_85428144	0.43	SYTL2	synaptotagmin-like 2	290	0.9
chr9_102849500_102849651	0.43	ERP44	endoplasmic reticulum protein 44	11747	0.18
chr12_11803298_11803449	0.43	ETV6	ets variant 6	585	0.83
chr18_32626039_32626502	0.43	MAPRE2	microtubule-associated protein, RP/EB family, member 2	4656	0.33
chr3_69129681_69129838	0.43	UBA3	ubiquitin-like modifier activating enzyme 3	200	0.92
chr20_3388735_3389323	0.43	C20orf194	chromosome 20 open reading frame 194	757	0.58
chr15_70050953_70051104	0.42	ENSG00000215958	.	26815	0.2
chr14_92339571_92339902	0.42	FBLN5	fibulin 5	4650	0.23
chr1_6265069_6265320	0.42	RP1-120G22.11		646	0.44
chr17_78705219_78705370	0.42	RP11-28G8.1		74138	0.1
chr12_51319990_51320253	0.42	METTL7A	methyltransferase like 7A	1587	0.32
chrX_72782625_72782944	0.42	CHIC1	cysteine-rich hydrophobic domain 1	252	0.96
chr1_168196715_168196866	0.42	SFT2D2	SFT2 domain containing 2	1535	0.4
chr6_13712533_13713141	0.42	RANBP9	RAN binding protein 9	1041	0.55
chr1_84611868_84612019	0.42	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	1989	0.45
chrX_76776329_76776480	0.42	FGF16	fibroblast growth factor 16	66756	0.13
chr14_53258594_53258962	0.42	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1	392	0.83
chr21_35014330_35014501	0.41	CRYZL1	crystallin, zeta (quinone reductase)-like 1	191	0.62
chr9_82185992_82186420	0.41	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	482	0.9
chr17_28085648_28085799	0.41	RP11-82O19.1		2398	0.25
chr11_18548581_18549104	0.41	TSG101	tumor susceptibility 101	63	0.97
chr14_35344279_35344957	0.41	BAZ1A	bromodomain adjacent to zinc finger domain, 1A	235	0.86
chr14_70111468_70111619	0.41	KIAA0247	KIAA0247	33230	0.18
chr15_64679591_64679870	0.41	TRIP4	thyroid hormone receptor interactor 4	273	0.85
chr3_107807562_107807961	0.41	CD47	CD47 molecule	2100	0.46
chr18_74781332_74781483	0.41	MBP	myelin basic protein	35810	0.21
chr21_35306376_35306527	0.41	LINC00649	long intergenic non-protein coding RNA 649	2933	0.21
chr7_106822662_106822813	0.41	HBP1	HMG-box transcription factor 1	2374	0.31
chr5_95155170_95155321	0.40	GLRX	glutaredoxin (thioltransferase)	3170	0.2
chr10_91151882_91152232	0.40	IFIT1	interferon-induced protein with tetratricopeptide repeats 1	246	0.89
chr19_23945488_23945685	0.40	RPSAP58	ribosomal protein SA pseudogene 58	221	0.93
chrY_2804248_2804778	0.40	ZFY	zinc finger protein, Y-linked	967	0.67
chr13_41372571_41372761	0.40	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	5372	0.18
chr14_42218977_42219275	0.40	LRFN5	leucine rich repeat and fibronectin type III domain containing 5	50496	0.19
chr1_186292481_186292673	0.40	ENSG00000202025	.	11517	0.17
chr1_149784317_149784567	0.40	HIST2H2BF	histone cluster 2, H2bf	514	0.4
chr1_169679248_169679951	0.39	SELL	selectin L	1240	0.48
chr12_14520726_14520877	0.39	ATF7IP	activating transcription factor 7 interacting protein	494	0.85
chr1_100852790_100852941	0.39	ENSG00000216067	.	8534	0.21
chr4_1514296_1514447	0.39	NKX1-1	NK1 homeobox 1	114252	0.05
chr8_8203302_8203453	0.39	SGK223	Tyrosine-protein kinase SgK223	35880	0.18
chr4_95635906_95636061	0.39	BMPR1B	bone morphogenetic protein receptor, type IB	43136	0.21
chr12_117036678_117036829	0.39	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2	23097	0.24
chrX_25020829_25021251	0.39	ARX	aristaless related homeobox	13025	0.26
chr5_138180468_138180657	0.39	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	29165	0.16
chr3_151987754_151988434	0.39	MBNL1-AS1	MBNL1 antisense RNA 1	750	0.48
chr4_143321296_143321548	0.39	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	30990	0.26
chr16_10838130_10838300	0.39	NUBP1	nucleotide binding protein 1	503	0.79
chr18_46455022_46455234	0.38	SMAD7	SMAD family member 7	19747	0.23
chr5_34007564_34007777	0.38	AMACR	alpha-methylacyl-CoA racemase	463	0.82
chr5_159846201_159846839	0.38	SLU7	SLU7 splicing factor homolog (S. cerevisiae)	119	0.95
chr6_26365020_26365256	0.38	BTN3A2	butyrophilin, subfamily 3, member A2	249	0.73
chr8_17520625_17520776	0.38	MTUS1	microtubule associated tumor suppressor 1	13138	0.17
chr14_90187580_90187856	0.38	ENSG00000200312	.	8863	0.23
chr6_25041553_25042305	0.38	RP3-425P12.5		138	0.72
chr11_62573118_62573460	0.38	NXF1	nuclear RNA export factor 1	325	0.66
chr3_135909805_135909956	0.38	MSL2	male-specific lethal 2 homolog (Drosophila)	3516	0.32
chr2_197662576_197662727	0.38	GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa	1732	0.37
chr16_85495950_85496210	0.37	ENSG00000264203	.	20982	0.23
chr1_29253817_29254129	0.37	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	12882	0.18
chr19_44598967_44599422	0.37	ZNF224	zinc finger protein 224	649	0.48
chr2_149403004_149403363	0.37	EPC2	enhancer of polycomb homolog 2 (Drosophila)	194	0.97
chr11_72849028_72849179	0.37	FCHSD2	FCH and double SH3 domains 2	2003	0.37
chr4_110736131_110736554	0.37	GAR1	GAR1 ribonucleoprotein	324	0.86
chr11_18417510_18417661	0.37	LDHA	lactate dehydrogenase A	228	0.89
chr5_119523820_119523971	0.37	ENSG00000251975	.	149453	0.05
chr6_5175090_5175241	0.37	ENSG00000265083	.	26609	0.18
chr5_74062161_74062312	0.37	NSA2	NSA2 ribosome biogenesis homolog (S. cerevisiae)	581	0.46
chr16_71935673_71935824	0.37	IST1	increased sodium tolerance 1 homolog (yeast)	6256	0.13
chr5_35861092_35861243	0.37	IL7R	interleukin 7 receptor	4173	0.24
chr5_159900576_159900727	0.36	ENSG00000265237	.	758	0.62

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.4	1.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	0.5	GO:0010447	response to acidic pH(GO:0010447)
0.2	0.8	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.4	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.4	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.4	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.3	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.7	GO:0002857	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.3	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.4	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.5	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.2	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.5	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.5	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1	0.3	GO:0006667	sphinganine metabolic process(GO:0006667)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:0009106	lipoate metabolic process(GO:0009106)
0.1	0.7	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	0.2	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.4	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.1	0.2	GO:0032060	bleb assembly(GO:0032060)
0.1	0.7	GO:0006376	mRNA splice site selection(GO:0006376)
0.1	0.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.1	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.3	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.1	0.2	GO:0015825	L-serine transport(GO:0015825)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.4	GO:0045116	protein neddylation(GO:0045116)
0.1	0.2	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.5	GO:0015671	oxygen transport(GO:0015671)
0.1	0.2	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1	0.2	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.2	GO:0060539	diaphragm development(GO:0060539)
0.1	0.2	GO:0060972	left/right pattern formation(GO:0060972)
0.1	0.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	0.2	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.2	GO:0070295	renal water absorption(GO:0070295)
0.1	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.4	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.2	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.2	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.2	GO:0002507	tolerance induction(GO:0002507)
0.0	0.4	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.2	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.3	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.4	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.2	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.4	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.4	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.3	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.2	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.2	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.3	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.2	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.2	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.3	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.6	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.2	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0021894	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	2.2	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0034311	sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.2	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0051900	regulation of mitochondrial depolarization(GO:0051900)
0.0	0.1	GO:0006273	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.6	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.3	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.2	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.2	GO:0034030	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.4	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0042436	tryptophan metabolic process(GO:0006568) tryptophan catabolic process(GO:0006569) indolalkylamine metabolic process(GO:0006586) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.8	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.5	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.3	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.2	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0048668	collateral sprouting(GO:0048668)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0	0.1	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.0	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0090192	regulation of glomerulus development(GO:0090192)
0.0	0.2	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) response to histamine(GO:0034776)
0.0	0.1	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.2	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.1	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.0	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.0	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.0	GO:0046882	regulation of follicle-stimulating hormone secretion(GO:0046880) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.0	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.3	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.0	0.1	GO:0090280	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0	0.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.7	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	1.0	GO:0006364	rRNA processing(GO:0006364)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0060479	lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0	0.0	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.2	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0032292	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.3	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.2	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	1.9	GO:0000375	RNA splicing, via transesterification reactions(GO:0000375)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0	0.0	GO:0035089	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.0	0.0	GO:0032908	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0	0.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.0	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0052552	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0	0.0	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.1	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.0	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.7	GO:0006839	mitochondrial transport(GO:0006839)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.0	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0030834	regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	1.1	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.4	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1	0.4	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	0.5	GO:0031010	ISWI-type complex(GO:0031010)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.4	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.3	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.1	GO:0001740	Barr body(GO:0001740)
0.1	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.2	GO:0070552	BRISC complex(GO:0070552)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	1.8	GO:0000786	nucleosome(GO:0000786)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.5	GO:0005771	multivesicular body(GO:0005771)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.0	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0030130	trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.8	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.5	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.9	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.7	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.4	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.4	GO:0005814	centriole(GO:0005814)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.5	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.4	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.9	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0050544	arachidonic acid binding(GO:0050544)
0.3	1.5	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	0.6	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.4	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.3	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	1.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.3	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.6	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	0.8	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.3	GO:0016854	racemase and epimerase activity(GO:0016854)
0.1	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.3	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.5	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1	0.3	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.1	0.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	0.2	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.2	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.2	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.2	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.2	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.3	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.3	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0003917	DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0	0.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.5	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.3	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.8	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.6	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.6	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.3	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.3	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.6	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.4	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.2	GO:0019783	ubiquitin-like protein-specific protease activity(GO:0019783)
0.0	0.0	GO:0045309	protein phosphorylated amino acid binding(GO:0045309) phosphoserine binding(GO:0050815)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.3	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.7	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.3	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.8	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.2	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.0	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.0	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.2	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.7	GO:0005178	integrin binding(GO:0005178)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0009008	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.0	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
1.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
1.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.5	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.9	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.7	PID PLK1 PATHWAY	PLK1 signaling events
0.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.3	PID ATR PATHWAY	ATR signaling pathway
0.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	2.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.7	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	1.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME PI 3K CASCADE	Genes involved in PI-3K cascade
0.0	0.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination

Results for VAX2_RHOXF2

Z-value: 1.15

Motif logo

Transcription factors associated with VAX2_RHOXF2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the VAX2_RHOXF2 motif across conditions

Conditions sorted by the z-value of the VAX2_RHOXF2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: