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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for VSX1

Z-value: 0.85

Motif logo

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Transcription factors associated with VSX1

Gene Symbol Gene ID Gene Info
VSX1
ENSG00000100987.10 visual system homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr20_25071710_25071861VSX187890.209651-0.472.0e-01Click!
chr20_25064794_25064945VSX118730.363721-0.452.3e-01Click!
chr20_25064515_25064666VSX115940.408889-0.235.5e-01Click!
chr20_25064050_25064221VSX111390.5248640.225.6e-01Click!
chr20_25064259_25064410VSX113380.4661580.059.1e-01Click!

Activity of the VSX1 motif across conditions

Conditions sorted by the z-value of the VSX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_12849556_12849989 0.42 RP11-47J17.3
4558
 0.23
chr16_62022994_62023145 0.38 CDH8
 cadherin 8, type 2
 32437
 0.22
chr3_112356169_112356393 0.37 CCDC80
 coiled-coil domain containing 80
 663
 0.77
chr15_96881050_96881298 0.31 ENSG00000222651
 .
 4684
 0.17
chr2_217235630_217236249 0.31 MARCH4
 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
 811
 0.59
chrX_34671991_34672311 0.30 TMEM47
 transmembrane protein 47
 3254
 0.41
chr10_25008347_25008498 0.30 ARHGAP21
 Rho GTPase activating protein 21
 2373
 0.41
chr17_66700653_66700804 0.28 ENSG00000263690
 .
 61972
 0.13
chr6_74226468_74226678 0.28 EEF1A1
 eukaryotic translation elongation factor 1 alpha 1
 4168
 0.13
chr15_96878465_96878729 0.28 ENSG00000222651
 .
 2107
 0.24
chr1_236046389_236046555 0.28 LYST
 lysosomal trafficking regulator
 400
 0.83
chr1_196577911_196578299 0.27 KCNT2
 potassium channel, subfamily T, member 2
 250
 0.94
chr6_111984874_111985025 0.27 ENSG00000239015
 .
 17319
 0.19
chr2_189158529_189158680 0.25 GULP1
 GULP, engulfment adaptor PTB domain containing 1
 59
 0.98
chr3_173266211_173266362 0.25 NLGN1
 neuroligin 1
 36059
 0.24
chr6_127780261_127780437 0.25 KIAA0408
 KIAA0408
 161
 0.97
chr1_164532131_164532342 0.25 PBX1
 pre-B-cell leukemia homeobox 1
 194
 0.97
chr1_245461989_245462162 0.25 RP11-62I21.1
64272
 0.12
chr11_31831142_31831293 0.24 PAX6
 paired box 6
 636
 0.72
chr11_106239153_106239583 0.24 RP11-680E19.1
104326
 0.08
chr1_99126586_99127126 0.24 SNX7
 sorting nexin 7
 380
 0.93
chr10_119564055_119564206 0.24 RP11-354M20.3
212868
 0.02
chr14_52534801_52535890 0.24 NID2
 nidogen 2 (osteonidogen)
 367
 0.89
chr12_18622010_18622161 0.24 PIK3C2G
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
 187107
 0.03
chr4_71997150_71997347 0.24 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 55755
 0.16
chr9_100069620_100070257 0.24 CCDC180
 coiled-coil domain containing 180
 3
 0.98
chr3_79067433_79067887 0.24 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
 34
 0.99
chr15_101261674_101262051 0.24 ENSG00000212306
 .
 83294
 0.08
chr8_121137253_121137925 0.24 COL14A1
 collagen, type XIV, alpha 1
 237
 0.96
chr20_56749874_56750278 0.23 C20orf85
 chromosome 20 open reading frame 85
 24116
 0.19
chr8_37350646_37351319 0.23 RP11-150O12.6
23557
 0.24
chr5_15501266_15501663 0.23 FBXL7
 F-box and leucine-rich repeat protein 7
 83
 0.99
chr6_85256272_85256423 0.23 RP11-132M7.3
142796
 0.05
chr4_123776122_123776354 0.22 ENSG00000253069
 .
 28069
 0.14
chr5_110429004_110429186 0.22 WDR36
 WD repeat domain 36
 1076
 0.41
chr11_124733143_124733554 0.22 ROBO3
 roundabout, axon guidance receptor, homolog 3 (Drosophila)
 1934
 0.2
chr19_9473504_9474272 0.22 ZNF177
 zinc finger protein 177
 181
 0.93
chr8_89336204_89336358 0.22 RP11-586K2.1
2784
 0.3
chr17_13503089_13503240 0.22 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
 2080
 0.42
chr1_76757094_76757245 0.22 ST6GALNAC3
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
 216765
 0.02
chr19_2185882_2186045 0.21 DOT1L
 DOT1-like histone H3K79 methyltransferase
 21779
 0.09
chr1_214723042_214723197 0.21 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 1447
 0.54
chr18_65188257_65188408 0.21 DSEL
 dermatan sulfate epimerase-like
 4115
 0.29
chr5_32803819_32803970 0.21 AC026703.1
14949
 0.22
chr14_24838154_24838623 0.21 NFATC4
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
 15
 0.95
chr16_86603613_86603777 0.21 RP11-463O9.5
2328
 0.23
chr1_162603392_162603656 0.21 DDR2
 discoidin domain receptor tyrosine kinase 2
 1264
 0.48
chr5_16916952_16917142 0.21 MYO10
 myosin X
 411
 0.87
chr12_19358284_19358561 0.21 PLEKHA5
 pleckstrin homology domain containing, family A member 5
 163
 0.96
chr5_16713576_16713796 0.21 MYO10
 myosin X
 24810
 0.21
chr11_8831505_8831934 0.20 ST5
 suppression of tumorigenicity 5
 477
 0.76
chr8_42063953_42065062 0.20 PLAT
 plasminogen activator, tissue
 576
 0.71
chr18_52721804_52722049 0.20 ENSG00000264804
 .
 53297
 0.15
chr13_24146066_24146217 0.20 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 1338
 0.59
chr12_65997242_65997414 0.20 HMGA2
 high mobility group AT-hook 2
 220583
 0.02
chr21_32591500_32591929 0.20 TIAM1
 T-cell lymphoma invasion and metastasis 1
 57369
 0.16
chr2_40098959_40099110 0.20 SLC8A1-AS1
 SLC8A1 antisense RNA 1
 47799
 0.18
chr17_45331851_45332126 0.20 ITGB3
 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
 725
 0.57
chr6_53928552_53928746 0.20 MLIP-AS1
 MLIP antisense RNA 1
 15875
 0.2
chr1_118238331_118238482 0.20 ENSG00000212266
 .
 7042
 0.28
chr2_157659750_157659995 0.20 ENSG00000263848
 .
 211897
 0.02
chr2_74606600_74607395 0.20 DCTN1
 dynactin 1
 413
 0.73
chr2_100297290_100297441 0.20 AFF3
 AF4/FMR2 family, member 3
 102533
 0.08
chr13_95003800_95004010 0.20 ENSG00000212057
 .
 113739
 0.06
chr13_96295623_96295774 0.20 DZIP1
 DAZ interacting zinc finger protein 1
 181
 0.96
chr13_24044512_24044663 0.19 SACS
 spastic ataxia of Charlevoix-Saguenay (sacsin)
 36746
 0.21
chr5_111090218_111090459 0.19 NREP
 neuronal regeneration related protein
 1610
 0.42
chr2_144692978_144693129 0.19 AC016910.1
1587
 0.49
chr13_33803610_33803839 0.19 STARD13
 StAR-related lipid transfer (START) domain containing 13
 23581
 0.2
chr18_60278197_60278407 0.19 ENSG00000243549
 .
 39532
 0.17
chr15_96886136_96886425 0.19 ENSG00000222651
 .
 9790
 0.16
chr13_111768316_111768682 0.19 ARHGEF7-AS2
 ARHGEF7 antisense RNA 2
 474
 0.54
chr4_81198150_81198317 0.19 FGF5
 fibroblast growth factor 5
 10440
 0.25
chr12_44131589_44131740 0.19 RP11-210N13.1
968
 0.56
chr1_182932139_182932350 0.19 ENSG00000264768
 .
 3534
 0.19
chr1_107682797_107683388 0.19 NTNG1
 netrin G1
 350
 0.93
chr6_52440366_52440800 0.19 TRAM2
 translocation associated membrane protein 2
 1130
 0.59
chr11_57530814_57530965 0.19 CTNND1
 catenin (cadherin-associated protein), delta 1
 436
 0.77
chr17_47547430_47548013 0.19 NGFR
 nerve growth factor receptor
 24934
 0.13
chr3_106060605_106060757 0.18 ENSG00000200610
 .
 174063
 0.04
chr11_111849006_111849202 0.18 DIXDC1
 DIX domain containing 1
 1071
 0.39
chr12_22059820_22060034 0.18 ABCC9
 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
 3985
 0.3
chr7_93552303_93552503 0.18 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
 1392
 0.38
chr9_98188423_98189086 0.18 PTCH1
 patched 1
 54013
 0.12
chr4_187025490_187026623 0.18 FAM149A
 family with sequence similarity 149, member A
 175
 0.94
chr15_39876247_39876621 0.18 THBS1
 thrombospondin 1
 3140
 0.25
chr10_18629419_18629841 0.18 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
 36
 0.99
chr4_52903402_52903553 0.18 SGCB
 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
 948
 0.59
chr15_57124208_57124359 0.18 ZNF280D
 zinc finger protein 280D
 86486
 0.09
chr12_105711891_105712042 0.18 RP11-474B16.1
8829
 0.18
chr6_155475558_155475911 0.18 TIAM2
 T-cell lymphoma invasion and metastasis 2
 5479
 0.3
chr16_56811456_56811607 0.18 NUP93
 nucleoporin 93kDa
 4039
 0.18
chr6_84743193_84743395 0.18 MRAP2
 melanocortin 2 receptor accessory protein 2
 181
 0.97
chr3_114343374_114343541 0.18 ZBTB20
 zinc finger and BTB domain containing 20
 335
 0.94
chr2_101435204_101435829 0.18 NPAS2
 neuronal PAS domain protein 2
 1098
 0.54
chr5_88129391_88129549 0.18 MEF2C
 myocyte enhancer factor 2C
 6495
 0.28
chr5_148786412_148786563 0.18 ENSG00000208035
 .
 21994
 0.11
chr3_63037895_63038046 0.18 CADPS
 Ca++-dependent secretion activator
 176916
 0.03
chr4_170188382_170188561 0.18 SH3RF1
 SH3 domain containing ring finger 1
 2637
 0.38
chr7_130606573_130606804 0.18 ENSG00000226380
 .
 44390
 0.16
chr14_62230360_62230511 0.18 SNAPC1
 small nuclear RNA activating complex, polypeptide 1, 43kDa
 1360
 0.55
chr9_104248314_104249564 0.17 TMEM246
 transmembrane protein 246
 460
 0.79
chr6_148829582_148830289 0.17 ENSG00000223322
 .
 15441
 0.29
chr4_78620774_78621041 0.17 ENSG00000221711
 .
 3050
 0.34
chr5_121648324_121648736 0.17 SNCAIP
 synuclein, alpha interacting protein
 268
 0.87
chr2_227834271_227834422 0.17 ENSG00000212391
 .
 508
 0.85
chr9_4927714_4927865 0.17 ENSG00000238362
 .
 40308
 0.13
chr2_134024891_134025042 0.17 AC010890.1
1152
 0.61
chr15_60685776_60685927 0.17 ANXA2
 annexin A2
 2355
 0.39
chr20_42544114_42544359 0.17 TOX2
 TOX high mobility group box family member 2
 554
 0.83
chrX_135287572_135287723 0.17 FHL1
 four and a half LIM domains 1
 767
 0.7
chr9_21688149_21688723 0.17 ENSG00000244230
 .
 10877
 0.24
chr11_126869922_126870139 0.17 KIRREL3
 kin of IRRE like 3 (Drosophila)
 386
 0.81
chr6_100729238_100729940 0.17 RP1-121G13.2
145405
 0.05
chr13_102105579_102105898 0.17 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
 720
 0.77
chr12_106812256_106812407 0.17 POLR3B
 polymerase (RNA) III (DNA directed) polypeptide B
 36581
 0.19
chr1_70406023_70406174 0.17 ENSG00000240692
 .
 60823
 0.14
chr4_81193524_81193675 0.17 FGF5
 fibroblast growth factor 5
 5806
 0.27
chr11_10962454_10962605 0.17 ZBED5-AS1
 ZBED5 antisense RNA 1
 75721
 0.09
chr13_73081776_73081993 0.17 ENSG00000251715
 .
 47145
 0.15
chr17_1914930_1915193 0.17 AC099684.1
5949
 0.1
chr18_12309689_12309931 0.17 TUBB6
 tubulin, beta 6 class V
 1156
 0.46
chr7_97361017_97361340 0.17 TAC1
 tachykinin, precursor 1
 42
 0.99
chr15_25936715_25936881 0.17 ATP10A
 ATPase, class V, type 10A
 3174
 0.29
chr9_94753972_94754242 0.17 ROR2
 receptor tyrosine kinase-like orphan receptor 2
 41663
 0.19
chr4_87517094_87517245 0.17 PTPN13
 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
 323
 0.88
chr3_61546098_61546562 0.17 PTPRG
 protein tyrosine phosphatase, receptor type, G
 1255
 0.64
chr8_22023419_22024083 0.17 BMP1
 bone morphogenetic protein 1
 951
 0.4
chr2_201651988_201652246 0.17 ENSG00000201737
 .
 11810
 0.12
chr17_1994078_1994475 0.17 RP11-667K14.5
1301
 0.3
chr2_181388977_181389207 0.17 ENSG00000264976
 .
 92841
 0.1
chr7_95107815_95108198 0.17 ASB4
 ankyrin repeat and SOCS box containing 4
 7207
 0.2
chr15_86167470_86167715 0.17 RP11-815J21.3
3328
 0.19
chr9_18476160_18476529 0.17 ADAMTSL1
 ADAMTS-like 1
 2113
 0.45
chr3_16024121_16024347 0.17 ENSG00000207815
 .
 108956
 0.06
chr5_91941448_91941599 0.17 ENSG00000221810
 .
 111697
 0.07
chr20_18720686_18720868 0.17 RP11-379J5.5
41424
 0.15
chr5_88238815_88238969 0.17 MEF2C-AS1
 MEF2C antisense RNA 1
 12
 0.99
chr7_70060715_70061143 0.16 AUTS2
 autism susceptibility candidate 2
 133196
 0.06
chr3_98619314_98619465 0.16 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 626
 0.66
chr5_112033189_112033368 0.16 APC
 adenomatous polyposis coli
 9917
 0.26
chr4_114898942_114899097 0.16 ARSJ
 arylsulfatase family, member J
 1133
 0.61
chr4_187646786_187647042 0.16 FAT1
 FAT atypical cadherin 1
 962
 0.7
chr15_33154166_33154394 0.16 FMN1
 formin 1
 26175
 0.19
chr11_122597673_122598179 0.16 ENSG00000239079
 .
 907
 0.67
chr1_93389452_93389603 0.16 FAM69A
 family with sequence similarity 69, member A
 37530
 0.1
chr3_54277662_54277813 0.16 CACNA2D3
 calcium channel, voltage-dependent, alpha 2/delta subunit 3
 65914
 0.14
chr10_63813819_63813970 0.16 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 4924
 0.3
chr9_137380907_137381058 0.16 RXRA
 retinoid X receptor, alpha
 82554
 0.09
chr8_97744511_97744662 0.16 CPQ
 carboxypeptidase Q
 28616
 0.25
chr1_45083000_45083241 0.16 RNF220
 ring finger protein 220
 8878
 0.17
chr5_31193803_31195028 0.16 CDH6
 cadherin 6, type 2, K-cadherin (fetal kidney)
 558
 0.85
chr7_87229218_87230455 0.16 ABCB1
 ATP-binding cassette, sub-family B (MDR/TAP), member 1
 336
 0.9
chr9_13278507_13279169 0.16 RP11-272P10.2
348
 0.67
chr10_105211471_105211777 0.16 CALHM2
 calcium homeostasis modulator 2
 451
 0.57
chr8_41165312_41165463 0.16 SFRP1
 secreted frizzled-related protein 1
 878
 0.57
chr20_25290950_25291163 0.16 ABHD12
 abhydrolase domain containing 12
 922
 0.6
chr11_58874492_58875123 0.16 FAM111B
 family with sequence similarity 111, member B
 97
 0.97
chr20_62600161_62600928 0.16 ZNF512B
 zinc finger protein 512B
 674
 0.45
chr8_27405445_27405654 0.16 CLU
 clusterin
 51983
 0.11
chr18_10660519_10660670 0.16 RP11-856M7.1
1336
 0.48
chr11_19585849_19586032 0.16 ENSG00000265210
 .
 10917
 0.19
chr5_71406834_71406985 0.16 MAP1B
 microtubule-associated protein 1B
 3596
 0.33
chr8_60190630_60190781 0.16 ENSG00000206853
 .
 140644
 0.05
chr4_114680711_114680982 0.16 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 1378
 0.6
chr9_21988401_21988572 0.16 CDKN2A
 cyclin-dependent kinase inhibitor 2A
 5924
 0.15
chr16_86353722_86353873 0.15 ENSG00000199949
 .
 44668
 0.19
chr6_131290698_131290904 0.15 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 822
 0.76
chr12_115135696_115136278 0.15 TBX3
 T-box 3
 14018
 0.21
chr22_28010083_28010492 0.15 RP11-375H17.1
102181
 0.08
chr6_39787271_39787422 0.15 DAAM2
 dishevelled associated activator of morphogenesis 2
 26552
 0.21
chr5_76979205_76979356 0.15 TBCA
 tubulin folding cofactor A
 31862
 0.19
chr21_17652021_17652264 0.15 ENSG00000201025
 .
 4947
 0.35
chr18_53089837_53090372 0.15 TCF4
 transcription factor 4
 361
 0.89
chr12_5294701_5295025 0.15 KCNA5
 potassium voltage-gated channel, shaker-related subfamily, member 5
 141778
 0.05
chr7_15724696_15724847 0.15 MEOX2
 mesenchyme homeobox 2
 1666
 0.46
chr12_13500259_13500486 0.15 C12orf36
 chromosome 12 open reading frame 36
 28992
 0.21
chr8_105235287_105235872 0.15 RIMS2
 regulating synaptic membrane exocytosis 2
 13
 0.99
chr8_93660376_93660527 0.15 ENSG00000221172
 .
 12888
 0.29
chr4_18595074_18595257 0.15 LCORL
 ligand dependent nuclear receptor corepressor-like
 571666
 0.0
chr6_5498160_5498518 0.15 RP1-232P20.1
40031
 0.2
chr17_38707848_38708142 0.15 CCR7
 chemokine (C-C motif) receptor 7
 9270
 0.17
chr10_110672045_110672364 0.15 ENSG00000222436
 .
 28864
 0.27
chr3_178787181_178787457 0.15 ZMAT3
 zinc finger, matrin-type 3
 2035
 0.36
chr1_226285926_226286101 0.15 H3F3A
 H3 histone, family 3A
 34335
 0.13
chr2_213401933_213402296 0.15 ERBB4
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
 1139
 0.66
chr7_130479581_130479757 0.15 KLF14
 Kruppel-like factor 14
 60781
 0.12
chr6_160151501_160151652 0.15 WTAP
 Wilms tumor 1 associated protein
 2956
 0.17
chr2_53795780_53795969 0.15 ENSG00000207456
 .
 1743
 0.47
chr6_3750219_3750380 0.15 RP11-420L9.5
1046
 0.5
chr2_188354408_188354559 0.15 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
 23885
 0.21
chr7_100777700_100777901 0.15 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 7421
 0.1
chr1_227413559_227414076 0.15 RP11-1B20.1
47783
 0.17
chr12_66220556_66220804 0.15 HMGA2
 high mobility group AT-hook 2
 1777
 0.39
chr17_9176686_9176837 0.15 RP11-85B7.4
9730
 0.26
chr1_54232654_54232848 0.15 ENSG00000201003
 .
 4075
 0.22
chr16_82687204_82687592 0.15 CDH13
 cadherin 13
 26700
 0.24
chr7_98734981_98735368 0.15 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
 6468
 0.25
chr11_121966638_121966789 0.15 ENSG00000207971
 .
 3839
 0.19
chr6_85896028_85896266 0.15 NT5E
 5'-nucleotidase, ecto (CD73)
 263662
 0.02

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of VSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.3 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.2 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.2 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:1904238 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0001840 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) regulation of apoptotic process involved in morphogenesis(GO:1902337) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) regulation of apoptotic process involved in development(GO:1904748)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.0 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.0 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0048538 thymus development(GO:0048538)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0010664 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0007350 blastoderm segmentation(GO:0007350)
0.0 0.1 GO:0009208 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656)
0.0 0.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.2 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0048242 epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0090026 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0055026 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0072172 ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0030427 site of polarized growth(GO:0030427)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0034739 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.0 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening