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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for ZBTB4

Z-value: 1.80

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Transcription factors associated with ZBTB4

Gene Symbol	Gene ID	Gene Info
ZBTB4 Ensembl NCBI GeneCards UniProt	ENSG00000174282.7	zinc finger and BTB domain containing 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_7381517_7381905	ZBTB4	1133	0.214985	0.74	2.2e-02	Click!
chr17_7383107_7383656	ZBTB4	537	0.458645	0.74	2.4e-02	Click!
chr17_7381090_7381241	ZBTB4	1679	0.138375	0.69	4.1e-02	Click!
chr17_7386497_7387192	ZBTB4	738	0.283606	0.66	5.4e-02	Click!
chr17_7381930_7382351	ZBTB4	704	0.371027	0.44	2.4e-01	Click!

Activity of the ZBTB4 motif across conditions

Conditions sorted by the z-value of the ZBTB4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_241496900_241497119	1.04	ANKMY1	ankyrin repeat and MYND domain containing 1	370	0.78
chr9_98075387_98075786	0.69	FANCC	Fanconi anemia, complementation group C	3590	0.32
chr5_96143451_96143616	0.66	ERAP1	endoplasmic reticulum aminopeptidase 1	79	0.96
chr5_92915594_92915963	0.64	ENSG00000237187	.	935	0.59
chr7_158766053_158766279	0.57	ENSG00000231419	.	34946	0.21
chr1_9555543_9555703	0.56	SLC25A33	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	43918	0.14
chr5_71404091_71404437	0.55	MAP1B	microtubule-associated protein 1B	951	0.69
chr20_36888419_36888669	0.54	BPI	bactericidal/permeability-increasing protein	7	0.93
chr2_95824188_95824339	0.54	ZNF514	zinc finger protein 514	819	0.61
chr12_57940037_57940279	0.51	DCTN2	dynactin 2 (p50)	746	0.4
chr13_24007498_24007984	0.50	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	100	0.98
chr1_154976041_154976288	0.49	ZBTB7B	zinc finger and BTB domain containing 7B	869	0.33
chr10_22541853_22542149	0.45	EBLN1	endogenous Bornavirus-like nucleoprotein 1	43051	0.13
chr12_72665965_72666270	0.43	ENSG00000236333	.	189	0.69
chr14_100705776_100706088	0.41	YY1	YY1 transcription factor	159	0.89
chr6_155054889_155055250	0.41	SCAF8	SR-related CTD-associated factor 8	519	0.85
chr9_80262701_80263060	0.40	GNA14	guanine nucleotide binding protein (G protein), alpha 14	343	0.91
chr12_56548859_56549010	0.40	MYL6B	myosin, light chain 6B, alkali, smooth muscle and non-muscle	2543	0.09
chr3_119812895_119813189	0.40	GSK3B	glycogen synthase kinase 3 beta	222	0.94
chr7_128694657_128694878	0.40	TNPO3	transportin 3	170	0.95
chr22_39713562_39713713	0.39	RPL3	ribosomal protein L3	982	0.32
chr16_75590196_75590347	0.39	TMEM231	transmembrane protein 231	87	0.95
chr2_9614364_9614568	0.38	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	193	0.94
chr10_128076891_128077106	0.37	ADAM12	ADAM metallopeptidase domain 12	26	0.99
chr11_126138529_126138703	0.37	SRPR	signal recognition particle receptor (docking protein)	238	0.63
chrX_100075462_100075959	0.37	CSTF2	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	185	0.93
chr1_46767195_46767446	0.37	LRRC41	leucine rich repeat containing 41	1960	0.23
chr4_184376644_184376795	0.36	CDKN2AIP	CDKN2A interacting protein	10869	0.18
chr11_40313079_40313230	0.36	LRRC4C	leucine rich repeat containing 4C	1526	0.54
chr2_849139_849290	0.36	AC113607.3		67596	0.11
chr18_52990549_52990700	0.36	TCF4	transcription factor 4	1099	0.65
chr15_91538087_91538585	0.35	PRC1	protein regulator of cytokinesis 1	523	0.64
chr6_31696965_31697269	0.35	DDAH2	dimethylarginine dimethylaminohydrolase 2	161	0.79
chr21_47518749_47519092	0.35	COL6A2	collagen, type VI, alpha 2	209	0.89
chr3_105587739_105587890	0.34	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	73	0.99
chr5_142227906_142228057	0.33	ARHGAP26-AS1	ARHGAP26 antisense RNA 1	20494	0.24
chr18_12658127_12658427	0.33	AP005482.1	Uncharacterized protein	32	0.6
chr16_12189304_12189493	0.33	RP11-276H1.2		234	0.92
chr17_14208549_14208700	0.33	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	4224	0.31
chr19_1439067_1439250	0.32	RPS15	ribosomal protein S15	352	0.66
chr11_114271853_114272228	0.32	RBM7	RNA binding motif protein 7	644	0.5
chr3_15642555_15642753	0.32	BTD	biotinidase	194	0.73
chr2_47085804_47085955	0.32	AC016722.3		5244	0.17
chr16_639668_639830	0.32	RAB40C	RAB40C, member RAS oncogene family	80	0.92
chr1_179199050_179199491	0.32	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	451	0.82
chr13_108870370_108870645	0.31	LIG4	ligase IV, DNA, ATP-dependent	209	0.51
chr9_93880706_93880989	0.31	AUH	AU RNA binding protein/enoyl-CoA hydratase	243330	0.02
chr2_191399313_191399526	0.31	TMEM194B	transmembrane protein 194B	29	0.67
chr2_38304114_38304579	0.31	CYP1B1-AS1	CYP1B1 antisense RNA 1	708	0.52
chr1_64384126_64384277	0.31	ENSG00000207190	.	110471	0.06
chr5_139988636_139988787	0.30	CD14	CD14 molecule	24525	0.06
chr4_152611909_152612083	0.30	RP11-164P12.3		16361	0.2
chr8_135534696_135534847	0.30	ZFAT	zinc finger and AT hook domain containing	12346	0.29
chr19_1237433_1237657	0.29	C19orf26	chromosome 19 open reading frame 26	445	0.65
chr12_6962053_6962347	0.29	USP5	ubiquitin specific peptidase 5 (isopeptidase T)	883	0.25
chr15_35280591_35280900	0.29	ZNF770	zinc finger protein 770	257	0.92
chr15_59064816_59065008	0.29	FAM63B	family with sequence similarity 63, member B	1351	0.36
chr4_89741949_89742221	0.29	FAM13A	family with sequence similarity 13, member A	2267	0.39
chr1_110882138_110882390	0.29	RBM15	RNA binding motif protein 15	319	0.59
chr19_34289389_34289540	0.29	KCTD15	potassium channel tetramerization domain containing 15	173	0.97
chrX_3733099_3733300	0.29	RP11-706O15.1	HCG1981372, isoform CRA_c; Uncharacterized protein	28699	0.23
chr8_74283083_74283286	0.28	RP11-434I12.2		14488	0.25
chr17_64301105_64301326	0.28	PRKCA	protein kinase C, alpha	2271	0.31
chr19_46194641_46194820	0.28	SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	299	0.72
chr7_117854626_117855054	0.28	ANKRD7	ankyrin repeat domain 7	9872	0.26
chr18_47794693_47794904	0.28	CCDC11	coiled-coil domain containing 11	1906	0.28
chr2_202987834_202988283	0.28	AC079354.3		6277	0.17
chr19_37019651_37020108	0.28	ZNF260	zinc finger protein 260	317	0.69
chr17_63556671_63556918	0.28	AXIN2	axin 2	119	0.98
chr11_57250397_57250659	0.28	RP11-624G17.3		5521	0.1
chr15_91446638_91446871	0.28	MAN2A2	mannosidase, alpha, class 2A, member 2	220	0.86
chr5_138210294_138210514	0.28	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	515	0.5
chr19_48248823_48248998	0.28	GLTSCR2	glioma tumor suppressor candidate region gene 2	131	0.94
chr11_118868805_118869524	0.28	CCDC84	coiled-coil domain containing 84	312	0.71
chr9_80263074_80263273	0.27	GNA14	guanine nucleotide binding protein (G protein), alpha 14	50	0.98
chr5_149379600_149379968	0.27	HMGXB3	HMG box domain containing 3	100	0.83
chr9_4679601_4679752	0.27	CDC37L1	cell division cycle 37-like 1	110	0.96
chr6_157099057_157099348	0.27	ARID1B	AT rich interactive domain 1B (SWI1-like)	116	0.95
chr11_113907214_113907377	0.27	ZBTB16	zinc finger and BTB domain containing 16	23020	0.18
chr3_193983115_193983362	0.27	CPN2	carboxypeptidase N, polypeptide 2	88809	0.07
chr12_111126086_111126403	0.27	HVCN1	hydrogen voltage-gated channel 1	270	0.91
chr6_26225383_26225534	0.27	HIST1H3E	histone cluster 1, H3e	75	0.9
chr1_224621785_224622065	0.27	WDR26	WD repeat domain 26	76	0.98
chr1_7844777_7844986	0.27	PER3	period circadian clock 3	118	0.95
chr8_13132829_13133895	0.27	DLC1	deleted in liver cancer 1	693	0.78
chr18_3282909_3283060	0.27	MYL12B	myosin, light chain 12B, regulatory	20030	0.15
chr10_30348121_30348418	0.27	KIAA1462	KIAA1462	184	0.97
chr5_118603924_118604075	0.26	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	388	0.86
chr5_34657053_34657223	0.26	RAI14	retinoic acid induced 14	188	0.54
chr22_46479838_46480037	0.26	FLJ27365	hsa-mir-4763	1946	0.18
chr19_48996311_48996470	0.26	LMTK3	lemur tyrosine kinase 3	18671	0.09
chr6_117804579_117805184	0.26	DCBLD1	discoidin, CUB and LCCL domain containing 1	1056	0.49
chr1_32802153_32802304	0.26	MARCKSL1	MARCKS-like 1	248	0.87
chr3_57582762_57582982	0.26	ARF4	ADP-ribosylation factor 4	180	0.8
chr17_7253148_7253469	0.26	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	328	0.67
chr19_30370336_30370487	0.26	URI1	URI1, prefoldin-like chaperone	44140	0.17
chr11_130318761_130319048	0.26	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15	35	0.98
chr17_4613343_4613641	0.26	ARRB2	arrestin, beta 2	292	0.78
chr6_18504157_18504385	0.26	ENSG00000207775	.	67744	0.12
chr11_120207222_120207426	0.26	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	463	0.81
chr9_136856225_136856578	0.26	VAV2	vav 2 guanine nucleotide exchange factor	1002	0.57
chr4_2110491_2110642	0.26	RP11-317B7.3		30834	0.13
chr1_35658429_35658728	0.25	SFPQ	splicing factor proline/glutamine-rich	171	0.94
chr22_45809646_45809858	0.25	RIBC2	RIB43A domain with coiled-coils 2	178	0.6
chrX_48335192_48335406	0.25	FTSJ1	FtsJ RNA methyltransferase homolog 1 (E. coli)	714	0.54
chr6_149638808_149638959	0.25	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	180	0.95
chr21_45553567_45553760	0.25	C21orf33	chromosome 21 open reading frame 33	2	0.97
chr3_105085070_105085295	0.25	ALCAM	activated leukocyte cell adhesion molecule	571	0.87
chr10_33621519_33621932	0.25	NRP1	neuropilin 1	1585	0.49
chr21_38444530_38444904	0.25	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P	394	0.68
chr1_231164485_231164696	0.25	ENSG00000221290	.	8920	0.15
chr16_30418975_30419177	0.25	ZNF771	zinc finger protein 771	126	0.9
chr14_23776071_23776801	0.25	BCL2L2-PABPN1	BCL2L2-PABPN1 readthrough	260	0.45
chr5_125936367_125936518	0.25	PHAX	phosphorylated adaptor for RNA export	482	0.79
chrX_40944624_40944775	0.25	USP9X	ubiquitin specific peptidase 9, X-linked	189	0.97
chrX_102631036_102631748	0.25	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	57	0.97
chr3_159482295_159482916	0.25	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough	287	0.9
chr6_36164778_36164969	0.25	RP1-179N16.6		107	0.53
chr2_202483531_202483851	0.25	ALS2CR11	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11	186	0.94
chr19_7600671_7600944	0.25	PNPLA6	patatin-like phospholipase domain containing 6	215	0.87
chr8_22926209_22926496	0.24	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	182	0.81
chr13_96705072_96705326	0.24	UGGT2	UDP-glucose glycoprotein glucosyltransferase 2	438	0.88
chr13_114567217_114567395	0.24	GAS6	growth arrest-specific 6	260	0.94
chr6_8109014_8109165	0.24	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	6278	0.27
chr20_45137101_45137252	0.24	ZNF334	zinc finger protein 334	1899	0.38
chr7_22766596_22766963	0.24	IL6	interleukin 6 (interferon, beta 2)	13	0.89
chr1_200343533_200343684	0.24	ZNF281	zinc finger protein 281	35512	0.23
chr1_211035458_211035755	0.24	KCNH1-IT1	KCNH1 intronic transcript 1 (non-protein coding)	271110	0.02
chr7_100136799_100136992	0.24	AGFG2	ArfGAP with FG repeats 2	13	0.95
chr6_24718784_24719286	0.24	C6orf62	chromosome 6 open reading frame 62	1191	0.38
chr11_64851678_64851910	0.24	ZFPL1	zinc finger protein-like 1	7	0.66
chr13_23412141_23412547	0.24	ENSG00000253094	.	35060	0.19
chr6_135509931_135510127	0.24	MYB	v-myb avian myeloblastosis viral oncogene homolog	2873	0.25
chr6_29855903_29856124	0.24	HLA-A	major histocompatibility complex, class I, A	53024	0.1
chr21_34638320_34638533	0.23	IL10RB-AS1	IL10RB antisense RNA 1 (head to head)	139	0.63
chr2_200775845_200776012	0.23	C2orf69	chromosome 2 open reading frame 69	51	0.97
chr6_56955318_56956098	0.23	ZNF451	zinc finger protein 451	703	0.71
chr14_61187848_61187999	0.23	SIX4	SIX homeobox 4	2929	0.28
chrX_129114490_129114653	0.23	BCORL1	BCL6 corepressor-like 1	2015	0.35
chr8_124169140_124169448	0.23	FAM83A	family with sequence similarity 83, member A	21993	0.11
chr11_128390451_128390699	0.23	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	1521	0.45
chr20_45338331_45338720	0.23	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10	399	0.86
chr12_113860437_113860657	0.23	SDSL	serine dehydratase-like	289	0.88
chr1_20834735_20834945	0.23	MUL1	mitochondrial E3 ubiquitin protein ligase 1	186	0.95
chr16_85062179_85062330	0.23	KIAA0513	KIAA0513	844	0.65
chr1_244614910_244615118	0.23	ADSS	adenylosuccinate synthase	422	0.85
chr1_22263119_22263468	0.23	HSPG2	heparan sulfate proteoglycan 2	497	0.73
chr20_37063682_37063920	0.22	ENSG00000200354	.	1160	0.28
chr5_102090983_102091186	0.22	PAM	peptidylglycine alpha-amidating monooxygenase	37	0.99
chrX_21857816_21858089	0.22	MBTPS2	membrane-bound transcription factor peptidase, site 2	180	0.95
chr5_154320942_154321226	0.22	MRPL22	mitochondrial ribosomal protein L22	422	0.82
chr1_178915119_178915294	0.22	RALGPS2	Ral GEF with PH domain and SH3 binding motif 2	59992	0.11
chr6_64282916_64283107	0.22	PTP4A1	protein tyrosine phosphatase type IVA, member 1	425	0.65
chr21_22372206_22372357	0.22	NCAM2	neural cell adhesion molecule 2	1399	0.61
chr3_61548441_61548635	0.22	PTPRG	protein tyrosine phosphatase, receptor type, G	953	0.73
chr19_39340461_39340619	0.22	HNRNPL	heterogeneous nuclear ribonucleoprotein L	40	0.93
chr19_12848601_12848882	0.22	ASNA1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	435	0.6
chrY_21237692_21237982	0.22	ENSG00000252766	.	56864	0.17
chr15_33011176_33011666	0.22	GREM1	gremlin 1, DAN family BMP antagonist	1216	0.49
chr17_75433594_75433745	0.22	ENSG00000200651	.	4522	0.17
chr12_116640040_116640191	0.22	RP11-115H15.2		21015	0.19
chr12_79846105_79846272	0.22	ENSG00000266390	.	10142	0.19
chr8_11058583_11058887	0.22	XKR6	XK, Kell blood group complex subunit-related family, member 6	113	0.96
chr6_31620204_31620418	0.22	BAG6	BCL2-associated athanogene 6	89	0.5
chr22_38074380_38074588	0.22	LGALS1	lectin, galactoside-binding, soluble, 1	2869	0.13
chr5_134210752_134210995	0.22	TXNDC15	thioredoxin domain containing 15	87	0.97
chr2_241526754_241527086	0.22	CAPN10	calpain 10	632	0.44
chr11_122072907_122073271	0.22	ENSG00000207994	.	50073	0.12
chr10_79398316_79398509	0.22	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	59	0.98
chrX_48432937_48433168	0.22	RBM3	RNA binding motif (RNP1, RRM) protein 3	126	0.62
chr17_46641896_46642241	0.22	HOXB-AS2	HOXB cluster antisense RNA 2	7444	0.07
chrX_135067752_135068122	0.21	SLC9A6	solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6	310	0.9
chr3_156323815_156324073	0.21	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	50971	0.13
chr17_65989983_65990154	0.21	C17orf58	chromosome 17 open reading frame 58	303	0.87
chr22_38667015_38667166	0.21	TMEM184B	transmembrane protein 184B	1580	0.26
chr11_96074357_96074658	0.21	ENSG00000266192	.	95	0.96
chr5_141030741_141031031	0.21	FCHSD1	FCH and double SH3 domains 1	57	0.96
chr8_48648492_48649280	0.21	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	2762	0.26
chr5_14148646_14149113	0.21	TRIO	trio Rho guanine nucleotide exchange factor	5050	0.35
chr19_1062828_1062979	0.21	HMHA1	histocompatibility (minor) HA-1	3019	0.12
chr2_131556092_131556243	0.21	AC133785.1		38400	0.11
chr17_38520724_38520875	0.21	GJD3	gap junction protein, delta 3, 31.9kDa	732	0.48
chr4_189203647_189204041	0.21	RP11-366H4.3		139311	0.05
chr6_27777859_27778065	0.21	HIST1H3H	histone cluster 1, H3h	120	0.89
chr1_155533628_155533926	0.21	ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)	1179	0.37
chr1_182992581_182992854	0.21	LAMC1	laminin, gamma 1 (formerly LAMB2)	122	0.97
chr10_126848105_126848411	0.21	CTBP2	C-terminal binding protein 2	810	0.75
chr13_28193516_28193784	0.21	LNX2	ligand of numb-protein X 2	891	0.49
chr8_74205022_74205806	0.21	RPL7	ribosomal protein L7	163	0.94
chr19_58341707_58341966	0.21	ZNF587B	zinc finger protein 587B	155	0.91
chr2_112070743_112070894	0.21	ENSG00000266139	.	7850	0.32
chr12_46385346_46385747	0.21	SCAF11	SR-related CTD-associated factor 11	357	0.93
chr8_48393517_48393668	0.21	SPIDR	scaffolding protein involved in DNA repair	40629	0.18
chr12_33592297_33592879	0.21	SYT10	synaptotagmin X	7	0.98
chr16_81437369_81437561	0.21	ENSG00000273048	.	18842	0.2
chr12_118809273_118809543	0.21	TAOK3	TAO kinase 3	1286	0.52
chr1_54871768_54871919	0.21	SSBP3	single stranded DNA binding protein 3	53	0.98
chr19_13409329_13409487	0.20	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	22698	0.18
chr7_115850994_115851250	0.20	TES	testis derived transcript (3 LIM domains)	519	0.82
chr9_86322674_86322842	0.20	UBQLN1	ubiquilin 1	91	0.72

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.8	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	0.4	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.6	GO:0017085	response to insecticide(GO:0017085)
0.1	0.7	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.3	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.3	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.3	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.5	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.1	0.6	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.2	GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1	0.2	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.3	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.2	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.2	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.2	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.7	GO:0006379	mRNA cleavage(GO:0006379)
0.1	0.3	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.1	0.2	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.1	GO:0001714	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.2	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.1	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.2	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475)
0.1	0.2	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.1	0.1	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.3	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.1	GO:0071504	cellular response to heparin(GO:0071504)
0.1	0.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.3	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	0.2	GO:0030011	maintenance of cell polarity(GO:0030011)
0.1	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.2	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.1	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.1	0.2	GO:0009405	pathogenesis(GO:0009405)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.2	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.3	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.3	GO:0060039	pericardium development(GO:0060039)
0.0	0.3	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.2	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.2	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.2	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.2	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.2	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.2	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.2	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.2	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0034443	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.8	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.2	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.2	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:1901021	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.2	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0022011	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.2	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.1	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.3	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.2	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0	0.0	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.3	GO:0009268	response to pH(GO:0009268)
0.0	0.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.0	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.2	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.3	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.0	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.2	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.0	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	0.0	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.0	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.2	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.2	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.0	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.3	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.1	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0033233	regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.1	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0	0.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.2	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.7	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0	0.2	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0033605	positive regulation of catecholamine secretion(GO:0033605)
0.0	0.0	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.2	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.0	0.0	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.2	GO:0051225	spindle assembly(GO:0051225)
0.0	0.0	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.0	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0032431	positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0043243	positive regulation of protein complex disassembly(GO:0043243) positive regulation of protein depolymerization(GO:1901881)
0.0	0.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.2	GO:0061641	DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:0060009	Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.0	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.0	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.2	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.3	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.0	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.0	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.2	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0072239	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0032324	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:1990748	removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0008542	visual learning(GO:0008542)
0.0	0.0	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.3	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.1	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.7	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.2	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.3	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.4	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.0	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	1.2	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.0	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.6	GO:0005876	spindle microtubule(GO:0005876)
0.0	1.0	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.2	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.0	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	1.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.4	GO:0009295	nucleoid(GO:0009295)
0.0	0.3	GO:0043204	perikaryon(GO:0043204)
0.0	0.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.0	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.2	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.0	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.0	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.9	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	0.4	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.3	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.7	GO:0070628	proteasome binding(GO:0070628)
0.1	0.5	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.6	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.3	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.2	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.4	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.6	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.2	GO:0046980	tapasin binding(GO:0046980)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.3	GO:0032407	MutSalpha complex binding(GO:0032407)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.1	GO:0046978	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1	0.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.3	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.4	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.9	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.4	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.3	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0032138	guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.2	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.2	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.6	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0032405	dinucleotide insertion or deletion binding(GO:0032139) MutLalpha complex binding(GO:0032405)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.0	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.4	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	1.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.0	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	1.3	GO:0008168	methyltransferase activity(GO:0008168)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0019843	rRNA binding(GO:0019843)
0.0	1.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.3	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.0	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0071617	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.2	GO:0031418	L-ascorbic acid binding(GO:0031418)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	1.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.6	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.5	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.2	PID ATM PATHWAY	ATM pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.5	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1	0.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.4	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.8	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.5	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle

Results for ZBTB4

Z-value: 1.80

Motif logo

Transcription factors associated with ZBTB4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ZBTB4 motif across conditions

Conditions sorted by the z-value of the ZBTB4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: