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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZBTB49

Z-value: 0.80

Motif logo

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Transcription factors associated with ZBTB49

Gene Symbol Gene ID Gene Info
ZBTB49
ENSG00000168826.11 zinc finger and BTB domain containing 49

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_4316995_4317146ZBTB49127160.1764570.501.7e-01Click!
chr4_4316659_4316810ZBTB49123800.1770300.343.7e-01Click!
chr4_4292047_4292578ZBTB493160.576045-0.107.9e-01Click!
chr4_4317457_4317608ZBTB49131780.1756780.039.3e-01Click!

Activity of the ZBTB49 motif across conditions

Conditions sorted by the z-value of the ZBTB49 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_6481304_6482171 0.83 DENND1C
 DENN/MADD domain containing 1C
 27
 0.95
chr19_2084034_2084229 0.62 MOB3A
 MOB kinase activator 3A
 1260
 0.31
chr21_46340531_46340791 0.60 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 109
 0.73
chr12_15111636_15111984 0.56 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 2390
 0.25
chr17_3818740_3818909 0.50 P2RX1
 purinergic receptor P2X, ligand-gated ion channel, 1
 970
 0.51
chr17_47819247_47819793 0.50 FAM117A
 family with sequence similarity 117, member A
 17631
 0.14
chr7_155150623_155150868 0.46 BLACE
 B-cell acute lymphoblastic leukemia expressed
 9884
 0.18
chr4_40207688_40207871 0.44 RHOH
 ras homolog family member H
 5815
 0.23
chr10_101290718_101290924 0.44 RP11-129J12.2
113
 0.96
chr19_42052588_42052799 0.39 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 3193
 0.22
chr19_35939406_35939567 0.38 FFAR2
 free fatty acid receptor 2
 283
 0.85
chr6_159465648_159465970 0.38 TAGAP
 T-cell activation RhoGTPase activating protein
 241
 0.93
chr3_53206269_53206420 0.37 PRKCD
 protein kinase C, delta
 7199
 0.18
chr8_8377701_8378015 0.34 ENSG00000263616
 .
 62307
 0.13
chr19_18507519_18507670 0.34 LRRC25
 leucine rich repeat containing 25
 827
 0.4
chr8_27183037_27183778 0.33 PTK2B
 protein tyrosine kinase 2 beta
 326
 0.9
chr2_175459196_175459684 0.33 WIPF1
 WAS/WASL interacting protein family, member 1
 3053
 0.24
chr11_117856643_117857627 0.33 IL10RA
 interleukin 10 receptor, alpha
 26
 0.98
chr17_76254452_76254830 0.32 TMEM235
 transmembrane protein 235
 26519
 0.12
chr16_88714887_88715038 0.31 CYBA
 cytochrome b-245, alpha polypeptide
 1729
 0.19
chr4_15661026_15661177 0.30 FBXL5
 F-box and leucine-rich repeat protein 5
 386
 0.87
chr2_43233189_43233340 0.29 ENSG00000207087
 .
 85368
 0.1
chr17_66286056_66286766 0.29 SLC16A6
 solute carrier family 16, member 6
 846
 0.47
chr19_17862364_17862733 0.28 FCHO1
 FCH domain only 1
 203
 0.91
chr17_70715496_70715723 0.28 ENSG00000222545
 .
 4999
 0.28
chr17_75868336_75868487 0.27 FLJ45079
10248
 0.24
chr1_28452162_28452313 0.26 ENSG00000253005
 .
 17115
 0.12
chr3_30653355_30653657 0.26 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 5413
 0.33
chrX_12989756_12990021 0.26 TMSB4X
 thymosin beta 4, X-linked
 3339
 0.29
chr15_90728173_90728877 0.26 SEMA4B
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
 330
 0.84
chr17_74072761_74073180 0.26 GALR2
 galanin receptor 2
 2095
 0.17
chr22_50752570_50752748 0.26 XX-C283C717.1
401
 0.71
chr21_39844669_39844875 0.25 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 25573
 0.26
chr17_33379941_33380092 0.25 ENSG00000238858
 .
 1497
 0.28
chr11_14665333_14666638 0.24 PDE3B
 phosphodiesterase 3B, cGMP-inhibited
 608
 0.56
chr17_4487766_4488160 0.23 SMTNL2
 smoothelin-like 2
 129
 0.94
chr3_190306633_190306784 0.23 IL1RAP
 interleukin 1 receptor accessory protein
 25473
 0.22
chr10_73572268_73572419 0.23 CDH23
 cadherin-related 23
 16815
 0.17
chr20_20692062_20692434 0.23 RALGAPA2
 Ral GTPase activating protein, alpha subunit 2 (catalytic)
 883
 0.69
chr3_53156917_53157068 0.22 RFT1
 RFT1 homolog (S. cerevisiae)
 7435
 0.19
chr17_72008833_72008984 0.22 RPL38
 ribosomal protein L38
 190813
 0.02
chr8_134088694_134088845 0.22 SLA
 Src-like-adaptor
 16166
 0.23
chr12_105044004_105044155 0.22 ENSG00000264295
 .
 58668
 0.13
chr3_172429057_172429256 0.22 NCEH1
 neutral cholesterol ester hydrolase 1
 148
 0.95
chr11_128591931_128592082 0.22 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 26088
 0.16
chr3_57038204_57038355 0.22 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 26876
 0.18
chr17_79005386_79005537 0.22 BAIAP2
 BAI1-associated protein 2
 3489
 0.16
chr6_37140965_37141167 0.22 PIM1
 pim-1 oncogene
 3087
 0.24
chr19_51971494_51971730 0.21 CEACAM18
 carcinoembryonic antigen-related cell adhesion molecule 18
 8226
 0.1
chr19_10405987_10406645 0.21 ICAM5
 intercellular adhesion molecule 5, telencephalin
 4663
 0.08
chr16_88767682_88768006 0.21 RNF166
 ring finger protein 166
 833
 0.34
chr18_74843262_74844680 0.21 MBP
 myelin basic protein
 331
 0.94
chr17_40398832_40398983 0.21 RP11-358B23.5
21698
 0.1
chr17_29821977_29822128 0.21 RAB11FIP4
 RAB11 family interacting protein 4 (class II)
 6926
 0.14
chr14_97204377_97204528 0.21 VRK1
 vaccinia related kinase 1
 59189
 0.14
chr12_66585568_66585719 0.20 IRAK3
 interleukin-1 receptor-associated kinase 3
 2606
 0.24
chr17_74261907_74262739 0.20 UBALD2
 UBA-like domain containing 2
 539
 0.68
chr17_55363036_55363187 0.20 MSI2
 musashi RNA-binding protein 2
 94
 0.98
chr9_137820763_137820914 0.20 FCN1
 ficolin (collagen/fibrinogen domain containing) 1
 11029
 0.14
chr1_37943283_37943786 0.20 ZC3H12A
 zinc finger CCCH-type containing 12A
 3381
 0.18
chr16_57721437_57721588 0.19 CCDC135
 coiled-coil domain containing 135
 7193
 0.13
chr3_43221968_43222122 0.19 ENSG00000222331
 .
 30318
 0.18
chr17_74581180_74582274 0.19 ST6GALNAC2
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
 483
 0.62
chr1_12533236_12533387 0.19 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 5293
 0.24
chr9_138844390_138844541 0.18 UBAC1
 UBA domain containing 1
 8761
 0.2
chr13_34116508_34116659 0.18 STARD13
 StAR-related lipid transfer (START) domain containing 13
 191816
 0.03
chr18_74184609_74184760 0.18 ZNF516
 zinc finger protein 516
 18051
 0.17
chrX_123105759_123105910 0.18 STAG2
 stromal antigen 2
 8814
 0.25
chr3_5071207_5071358 0.18 BHLHE40-AS1
 BHLHE40 antisense RNA 1
 49636
 0.12
chr17_75877482_75877763 0.18 FLJ45079
1037
 0.6
chr11_74952584_74952761 0.18 TPBGL
 trophoblast glycoprotein-like
 722
 0.6
chr19_44283632_44284486 0.18 KCNN4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
 1350
 0.33
chr15_90608186_90608365 0.17 ZNF710
 zinc finger protein 710
 2971
 0.2
chr4_166128900_166129705 0.17 KLHL2
 kelch-like family member 2
 327
 0.55
chr16_53980634_53980785 0.17 FTO
 fat mass and obesity associated
 12767
 0.21
chr1_185284734_185285261 0.17 IVNS1ABP
 influenza virus NS1A binding protein
 1464
 0.44
chr21_46899502_46899653 0.17 COL18A1
 collagen, type XVIII, alpha 1
 10612
 0.2
chr15_31507532_31508310 0.17 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
 54445
 0.15
chr17_46565994_46566145 0.17 ENSG00000206805
 .
 9610
 0.12
chr2_238263784_238263935 0.16 COL6A3
 collagen, type VI, alpha 3
 32861
 0.18
chr16_53552293_53552836 0.16 AKTIP
 AKT interacting protein
 14241
 0.21
chr15_50399834_50400002 0.16 ATP8B4
 ATPase, class I, type 8B, member 4
 6783
 0.25
chr3_52287768_52287956 0.16 PPM1M
 protein phosphatase, Mg2+/Mn2+ dependent, 1M
 4885
 0.1
chr12_54610003_54610573 0.16 ENSG00000265371
 .
 14972
 0.1
chr5_65440502_65441175 0.16 SREK1
 splicing regulatory glutamine/lysine-rich protein 1
 175
 0.55
chr9_97402187_97402338 0.16 FBP1
 fructose-1,6-bisphosphatase 1
 157
 0.97
chr3_14851561_14851984 0.15 FGD5
 FYVE, RhoGEF and PH domain containing 5
 8697
 0.23
chrX_153209082_153209233 0.15 RENBP
 renin binding protein
 982
 0.33
chr22_33223114_33223265 0.15 TIMP3
 TIMP metallopeptidase inhibitor 3
 25502
 0.21
chr21_16886585_16887016 0.15 ENSG00000212564
 .
 99802
 0.08
chr20_60760834_60760985 0.15 MTG2
 mitochondrial ribosome-associated GTPase 2
 2802
 0.2
chr18_24281915_24282066 0.15 ENSG00000265369
 .
 12497
 0.22
chr14_100533458_100533776 0.15 EVL
 Enah/Vasp-like
 843
 0.55
chr14_101013926_101014082 0.15 BEGAIN
 brain-enriched guanylate kinase-associated
 431
 0.78
chr2_135676446_135677712 0.15 CCNT2
 cyclin T2
 684
 0.48
chr3_30683174_30683325 0.15 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 35156
 0.21
chr13_28365022_28365726 0.15 GSX1
 GS homeobox 1
 1406
 0.47
chr12_51402747_51402967 0.15 SLC11A2
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
 175
 0.93
chr11_48069657_48069808 0.14 AC103828.1
32325
 0.16
chr22_50968790_50969317 0.14 TYMP
 thymidine phosphorylase
 568
 0.45
chr1_36838180_36838356 0.14 STK40
 serine/threonine kinase 40
 11327
 0.12
chr19_19599372_19599523 0.14 GATAD2A
 GATA zinc finger domain containing 2A
 23157
 0.1
chr18_11883181_11883332 0.14 MPPE1
 metallophosphoesterase 1
 6158
 0.13
chrX_95939817_95940209 0.14 DIAPH2
 diaphanous-related formin 2
 302
 0.93
chr1_182758950_182759312 0.14 NPL
 N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
 220
 0.94
chr21_36280449_36280667 0.14 RUNX1
 runt-related transcription factor 1
 18471
 0.28
chr19_35609321_35609472 0.14 FXYD3
 FXYD domain containing ion transport regulator 3
 38
 0.95
chr11_65291429_65291724 0.14 SCYL1
 SCY1-like 1 (S. cerevisiae)
 972
 0.38
chr9_90937776_90937927 0.13 ENSG00000252299
 .
 51333
 0.16
chrX_131623914_131624431 0.13 MBNL3
 muscleblind-like splicing regulator 3
 176
 0.97
chr2_74063742_74063893 0.13 STAMBP
 STAM binding protein
 7659
 0.18
chr4_657472_657717 0.13 PDE6B
 phosphodiesterase 6B, cGMP-specific, rod, beta
 35
 0.95
chr14_35591199_35591715 0.13 KIAA0391
 KIAA0391
 52
 0.51
chr14_93672992_93673380 0.13 C14orf142
 chromosome 14 open reading frame 142
 188
 0.52
chr11_94962772_94964135 0.13 RP11-712B9.2
103
 0.93
chr4_6695738_6695889 0.13 S100P
 S100 calcium binding protein P
 1017
 0.4
chr7_142012838_142012989 0.13 PRSS3P3
 protease, serine, 3 pseudogene 3
 23304
 0.2
chr7_26952596_26952747 0.13 SKAP2
 src kinase associated phosphoprotein 2
 48309
 0.14
chr21_45285452_45286244 0.13 AGPAT3
 1-acylglycerol-3-phosphate O-acyltransferase 3
 781
 0.65
chr6_14734934_14735085 0.13 ENSG00000206960
 .
 88243
 0.1
chr15_31650164_31650315 0.13 KLF13
 Kruppel-like factor 13
 8118
 0.31
chr16_58018530_58018844 0.13 TEPP
 testis, prostate and placenta expressed
 8348
 0.13
chr17_27716871_27717334 0.12 TAOK1
 TAO kinase 1
 380
 0.47
chr5_175560458_175560649 0.12 FAM153B
 family with sequence similarity 153, member B
 48644
 0.12
chr6_33545433_33545584 0.12 BAK1
 BCL2-antagonist/killer 1
 2473
 0.2
chr4_88770427_88770578 0.12 MEPE
 matrix extracellular phosphoglycoprotein
 16363
 0.19
chr10_101689512_101689663 0.12 DNMBP
 dynamin binding protein
 1166
 0.47
chr9_130666481_130666789 0.12 ST6GALNAC6
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
 974
 0.33
chr8_95652342_95652927 0.12 ESRP1
 epithelial splicing regulatory protein 1
 668
 0.52
chr19_2164749_2165707 0.12 DOT1L
 DOT1-like histone H3K79 methyltransferase
 1044
 0.38
chr7_142902930_142903081 0.12 TAS2R40
 taste receptor, type 2, member 40
 16125
 0.11
chr2_2690202_2690353 0.12 ENSG00000263570
 .
 330825
 0.01
chr16_56703515_56703666 0.12 MT1H
 metallothionein 1H
 136
 0.88
chr4_53525685_53526428 0.12 USP46
 ubiquitin specific peptidase 46
 554
 0.78
chr7_997543_997694 0.12 ADAP1
 ArfGAP with dual PH domains 1
 2575
 0.2
chr16_81480914_81481100 0.12 CMIP
 c-Maf inducing protein
 2232
 0.39
chr7_142510250_142510438 0.11 PRSS3P2
 protease, serine, 3 pseudogene 2
 29213
 0.14
chr11_66311190_66311580 0.11 ZDHHC24
 zinc finger, DHHC-type containing 24
 2321
 0.15
chr5_156692539_156692693 0.11 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 475
 0.65
chr12_50156324_50156475 0.11 TMBIM6
 transmembrane BAX inhibitor motif containing 6
 9652
 0.16
chr2_162100897_162101225 0.11 AC009299.2
6612
 0.21
chr6_42018642_42019010 0.11 TAF8
 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
 164
 0.87
chr19_34669041_34669419 0.11 LSM14A
 LSM14A, SCD6 homolog A (S. cerevisiae)
 5667
 0.28
chr2_219085570_219085950 0.11 ARPC2
 actin related protein 2/3 complex, subunit 2, 34kDa
 3827
 0.15
chr2_219233529_219233805 0.11 ENSG00000225062
 .
 1109
 0.3
chr17_65417991_65418142 0.11 ENSG00000201547
 .
 13069
 0.14
chr19_10704746_10704897 0.11 AP1M2
 adaptor-related protein complex 1, mu 2 subunit
 6830
 0.1
chr13_48893876_48894215 0.11 RB1
 retinoblastoma 1
 16134
 0.25
chr11_45101502_45101653 0.11 PRDM11
 PR domain containing 11
 13987
 0.27
chr19_3275241_3275448 0.11 AC010649.1
27575
 0.14
chr7_86946956_86947107 0.11 CROT
 carnitine O-octanoyltransferase
 27966
 0.2
chr9_96708088_96708484 0.11 BARX1
 BARX homeobox 1
 7427
 0.27
chr9_67671299_67671450 0.11 ENSG00000199432
 .
 93148
 0.07
chr15_67316943_67317094 0.11 SMAD3
 SMAD family member 3
 39083
 0.2
chr8_101964485_101964756 0.11 YWHAZ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
 160
 0.95
chr1_38019125_38019899 0.11 SNIP1
 Smad nuclear interacting protein 1
 391
 0.79
chr22_45625958_45626109 0.11 KIAA0930
 KIAA0930
 3249
 0.23
chr1_95582420_95583278 0.11 TMEM56
 transmembrane protein 56
 45
 0.91
chr21_34440256_34440407 0.11 OLIG1
 oligodendrocyte transcription factor 1
 2119
 0.27
chr13_20795977_20796128 0.11 GJB6
 gap junction protein, beta 6, 30kDa
 9065
 0.2
chr7_156797777_156797998 0.11 MNX1-AS2
 MNX1 antisense RNA 2
 1114
 0.45
chr9_139925276_139925479 0.11 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 2085
 0.1
chr5_153422227_153422378 0.10 MFAP3
 microfibrillar-associated protein 3
 3743
 0.24
chr3_45718385_45718593 0.10 LIMD1-AS1
 LIMD1 antisense RNA 1
 11885
 0.18
chrX_103357104_103358067 0.10 ZCCHC18
 zinc finger, CCHC domain containing 18
 383
 0.86
chr3_56949082_56949233 0.10 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 1342
 0.51
chr13_25115593_25116500 0.10 ENSG00000266216
 .
 13405
 0.17
chr16_84631467_84631681 0.10 RP11-61F12.1
3575
 0.21
chr17_25659717_25660000 0.10 WSB1
 WD repeat and SOCS box containing 1
 38486
 0.16
chr1_182808109_182808399 0.10 DHX9
 DEAH (Asp-Glu-Ala-His) box helicase 9
 250
 0.93
chr4_16083981_16084260 0.10 PROM1
 prominin 1
 111
 0.98
chr3_36985452_36986747 0.10 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
 449
 0.83
chr17_36859477_36859845 0.10 ENSG00000265930
 .
 1077
 0.24
chr9_123922153_123922304 0.10 CNTRL
 centriolin
 2107
 0.3
chr2_118943251_118943914 0.10 INSIG2
 insulin induced gene 2
 97532
 0.08
chr2_62530766_62530917 0.10 ENSG00000238809
 .
 38711
 0.15
chr9_136207992_136208143 0.10 ENSG00000201451
 .
 3406
 0.08
chr22_43253501_43253661 0.10 ARFGAP3
 ADP-ribosylation factor GTPase activating protein 3
 173
 0.96
chr19_14229110_14229381 0.10 PRKACA
 protein kinase, cAMP-dependent, catalytic, alpha
 349
 0.62
chr17_29814991_29815971 0.10 RAB11FIP4
 RAB11 family interacting protein 4 (class II)
 355
 0.83
chr14_78108377_78108627 0.10 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 25386
 0.16
chr12_104572024_104572175 0.10 TXNRD1
 thioredoxin reductase 1
 37458
 0.13
chr7_65216059_65216706 0.10 CCT6P1
 chaperonin containing TCP1, subunit 6 (zeta) pseudogene 1
 253
 0.9
chr17_36860259_36860862 0.10 MLLT6
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
 1235
 0.2
chr17_19093169_19093320 0.10 ENSG00000264940
 .
 314
 0.77
chr17_29399050_29399201 0.10 RP11-271K11.5
21081
 0.11
chr22_46988879_46989444 0.10 GRAMD4
 GRAM domain containing 4
 16135
 0.21
chr12_51716816_51717143 0.09 BIN2
 bridging integrator 2
 920
 0.52
chr9_102584292_102585830 0.09 NR4A3
 nuclear receptor subfamily 4, group A, member 3
 924
 0.68
chr4_57775517_57776061 0.09 REST
 RE1-silencing transcription factor
 1714
 0.37
chr16_4357890_4358162 0.09 GLIS2
 GLIS family zinc finger 2
 6736
 0.14
chr1_203676024_203676175 0.09 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
 16926
 0.18
chr14_91125349_91125500 0.09 TTC7B
 tetratricopeptide repeat domain 7B
 14872
 0.16
chr16_643128_643307 0.09 RAB40C
 RAB40C, member RAS oncogene family
 2885
 0.1
chr8_103251470_103251823 0.09 KB-431C1.4
24
 0.81
chr1_55616949_55617132 0.09 USP24
 ubiquitin specific peptidase 24
 63722
 0.11
chr9_127531935_127532859 0.09 RP11-175D17.3
5
 0.95
chr20_32700274_32700759 0.09 EIF2S2
 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
 378
 0.87
chr3_160473528_160474334 0.09 PPM1L
 protein phosphatase, Mg2+/Mn2+ dependent, 1L
 65
 0.95
chr17_1515004_1515155 0.09 ENSG00000238946
 .
 4510
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.2 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.4 GO:1990266 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.0 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling