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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for ZBTB6

Z-value: 0.92

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Transcription factors associated with ZBTB6

Gene Symbol	Gene ID	Gene Info
ZBTB6 Ensembl NCBI GeneCards UniProt	ENSG00000186130.4	zinc finger and BTB domain containing 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr9_125675329_125675840	ZBTB6	25	0.959156	0.79	1.1e-02	Click!
chr9_125674967_125675313	ZBTB6	469	0.701446	0.75	2.1e-02	Click!
chr9_125676053_125676214	ZBTB6	524	0.659660	0.08	8.4e-01	Click!

Activity of the ZBTB6 motif across conditions

Conditions sorted by the z-value of the ZBTB6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_93119065_93119528	0.44	RIN3	Ras and Rab interactor 3	450	0.88
chr18_60191384_60191660	0.43	ZCCHC2	zinc finger, CCHC domain containing 2	670	0.79
chr1_228463412_228463702	0.42	RP5-1139B12.3		190	0.86
chr19_17861983_17862176	0.39	FCHO1	FCH domain only 1	207	0.91
chr22_36424159_36424401	0.32	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	193	0.97
chr12_6554914_6555065	0.30	CD27	CD27 molecule	956	0.36
chr12_2904145_2904429	0.30	FKBP4	FK506 binding protein 4, 59kDa	168	0.92
chr1_45250267_45250455	0.29	BEST4	bestrophin 4	3016	0.09
chr16_1756328_1756636	0.29	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	288	0.8
chr1_92949920_92950071	0.28	GFI1	growth factor independent 1 transcription repressor	484	0.87
chr6_161694866_161695137	0.28	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	50	0.99
chr1_227751040_227751191	0.28	ZNF678	zinc finger protein 678	129	0.96
chr17_43339716_43339952	0.28	MAP3K14-AS1	MAP3K14 antisense RNA 1	276	0.54
chr9_6007144_6007398	0.27	KIAA2026	KIAA2026	516	0.47
chr3_13114529_13114680	0.27	IQSEC1	IQ motif and Sec7 domain 1	13	0.99
chr1_16533220_16533586	0.27	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19	365	0.77
chr3_52259939_52260090	0.27	TLR9	toll-like receptor 9	165	0.9
chr6_37138253_37138656	0.27	PIM1	pim-1 oncogene	475	0.81
chr17_72755238_72755446	0.27	SLC9A3R1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	2800	0.14
chr9_35096643_35096794	0.27	PIGO	phosphatidylinositol glycan anchor biosynthesis, class O	139	0.72
chr3_56950038_56950370	0.26	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	295	0.93
chr17_48227691_48228226	0.26	PPP1R9B	protein phosphatase 1, regulatory subunit 9B	81	0.94
chr1_47903753_47903904	0.25	FOXD2	forkhead box D2	2139	0.25
chrX_70330282_70330478	0.25	IL2RG	interleukin 2 receptor, gamma	368	0.76
chr9_130726612_130726763	0.25	FAM102A	family with sequence similarity 102, member A	13686	0.1
chr12_7061251_7061427	0.25	PTPN6	protein tyrosine phosphatase, non-receptor type 6	801	0.31
chr1_248904032_248904183	0.25	LYPD8	LY6/PLAUR domain containing 8	957	0.58
chr13_96329481_96329694	0.25	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	175	0.96
chr4_25235722_25235933	0.24	PI4K2B	phosphatidylinositol 4-kinase type 2 beta	230	0.95
chr4_6711291_6711527	0.24	MRFAP1L1	Morf4 family associated protein 1-like 1	198	0.92
chr1_226736465_226736625	0.24	C1orf95	chromosome 1 open reading frame 95	44	0.98
chr15_66998088_66998322	0.24	SMAD6	SMAD family member 6	2725	0.34
chr3_114014363_114014514	0.24	TIGIT	T cell immunoreceptor with Ig and ITIM domains	604	0.73
chr9_35650496_35650647	0.24	SIT1	signaling threshold regulating transmembrane adaptor 1	366	0.67
chr2_87883698_87883984	0.24	ENSG00000265507	.	45433	0.18
chr19_39056143_39056294	0.23	RYR1	ryanodine receptor 1 (skeletal)	1349	0.31
chr10_121249514_121249731	0.23	RGS10	regulator of G-protein signaling 10	37367	0.17
chr7_26191850_26192061	0.23	NFE2L3	nuclear factor, erythroid 2-like 3	95	0.97
chr1_167606739_167606890	0.23	RP3-455J7.4		6903	0.2
chr17_49197788_49197986	0.23	SPAG9	sperm associated antigen 9	208	0.92
chr7_99950179_99950442	0.22	PVRIG2P	poliovirus receptor related immunoglobulin domain containing 2, pseudogene	327	0.45
chr8_61429545_61429985	0.22	RAB2A	RAB2A, member RAS oncogene family	25	0.98
chr14_64009672_64010060	0.22	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	150	0.78
chr1_6052762_6052996	0.22	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	108	0.79
chr8_21777326_21777532	0.22	XPO7	exportin 7	161	0.95
chr10_81003096_81003247	0.22	ZMIZ1	zinc finger, MIZ-type containing 1	62804	0.13
chr17_28553116_28553267	0.22	SLC6A4	solute carrier family 6 (neurotransmitter transporter), member 4	9525	0.11
chr4_657188_657391	0.22	PDE6B	phosphodiesterase 6B, cGMP-specific, rod, beta	270	0.81
chr19_39108076_39108634	0.22	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	209	0.87
chr10_72575661_72575910	0.22	SGPL1	sphingosine-1-phosphate lyase 1	59	0.98
chr16_89043094_89043288	0.22	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	210	0.92
chr1_154981282_154981433	0.22	ZBTB7B	zinc finger and BTB domain containing 7B	5567	0.08
chr11_65341832_65341983	0.22	EHBP1L1	EH domain binding protein 1-like 1	1602	0.16
chr11_93451363_93451537	0.22	ENSG00000199875	.	1319	0.18
chr14_99734743_99735157	0.22	BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	2615	0.3
chr10_17243504_17243826	0.21	TRDMT1	tRNA aspartic acid methyltransferase 1	9	0.98
chr6_36514350_36514895	0.21	STK38	serine/threonine kinase 38	625	0.66
chr8_80942226_80942490	0.21	MRPS28	mitochondrial ribosomal protein S28	109	0.97
chr15_63796860_63797042	0.21	USP3	ubiquitin specific peptidase 3	96	0.98
chr3_124762810_124762961	0.21	HEG1	heart development protein with EGF-like domains 1	11917	0.19
chr17_76127593_76127800	0.21	TMC6	transmembrane channel-like 6	792	0.35
chr16_89005691_89005991	0.21	RP11-830F9.7		218	0.63
chr11_65407941_65408142	0.21	SIPA1	signal-induced proliferation-associated 1	258	0.8
chr16_4664641_4664890	0.21	UBALD1	UBA-like domain containing 1	108	0.93
chr4_89378287_89378543	0.21	HERC5	HECT and RLD domain containing E3 ubiquitin protein ligase 5	147	0.95
chr3_197283026_197283177	0.21	BDH1	3-hydroxybutyrate dehydrogenase, type 1	182	0.96
chr16_75681844_75682031	0.21	TERF2IP	telomeric repeat binding factor 2, interacting protein	253	0.6
chr14_100752270_100752487	0.20	AL157871.2		5415	0.1
chr12_122124689_122124840	0.20	MORN3	MORN repeat containing 3	17204	0.17
chrX_40944184_40944378	0.20	USP9X	ubiquitin specific peptidase 9, X-linked	607	0.84
chr21_44201507_44201919	0.20	AP001627.1		39845	0.16
chr6_139308621_139308842	0.20	REPS1	RALBP1 associated Eps domain containing 1	46	0.98
chr7_158937178_158937329	0.20	VIPR2	vasoactive intestinal peptide receptor 2	291	0.95
chr14_105528512_105528687	0.20	GPR132	G protein-coupled receptor 132	3168	0.24
chr9_6008187_6008379	0.20	KIAA2026	KIAA2026	382	0.53
chr6_99282558_99282847	0.20	POU3F2	POU class 3 homeobox 2	122	0.98
chr11_535772_535986	0.20	HRAS	Harvey rat sarcoma viral oncogene homolog	329	0.71
chr20_33865726_33865906	0.20	MMP24-AS1	MMP24 antisense RNA 1	14	0.59
chr17_7232727_7233032	0.20	NEURL4	neuralized E3 ubiquitin protein ligase 4	167	0.85
chr9_129088874_129089025	0.20	MVB12B	multivesicular body subunit 12B	179	0.97
chr1_38260135_38260459	0.20	MANEAL	mannosidase, endo-alpha-like	142	0.91
chr8_22435760_22435911	0.19	PDLIM2	PDZ and LIM domain 2 (mystique)	43	0.95
chr2_99069202_99069353	0.19	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	7864	0.24
chr7_6487296_6487531	0.19	DAGLB	diacylglycerol lipase, beta	150	0.95
chr20_62368732_62368892	0.19	LIME1	Lck interacting transmembrane adaptor 1	175	0.82
chr2_218930071_218930222	0.19	RUFY4	RUN and FYVE domain containing 4	3592	0.2
chr11_66313766_66314108	0.19	ZDHHC24	zinc finger, DHHC-type containing 24	228	0.86
chr19_932856_933060	0.19	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	449	0.64
chr5_71781171_71781322	0.19	ZNF366	zinc finger protein 366	21974	0.22
chr10_135089555_135089795	0.19	ADAM8	ADAM metallopeptidase domain 8	679	0.52
chr2_183580782_183581079	0.19	DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10	69	0.98
chr1_229478047_229478257	0.19	CCSAP	centriole, cilia and spindle-associated protein	112	0.96
chr16_50188787_50189022	0.19	PAPD5	PAP associated domain containing 5	1125	0.44
chr17_43302789_43303077	0.19	CTD-2020K17.1		3344	0.12
chr1_94374812_94375088	0.19	GCLM	glutamate-cysteine ligase, modifier subunit	16	0.98
chr12_131303058_131303233	0.19	ENSG00000238822	.	3247	0.24
chr6_27775872_27776194	0.19	HIST1H2AI	histone cluster 1, H2ai	134	0.69
chr19_35820197_35820463	0.19	CD22	CD22 molecule	215	0.83
chr11_128160980_128161131	0.19	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	214234	0.02
chrX_49116228_49116379	0.19	FOXP3	forkhead box P3	606	0.54
chr4_2845565_2845727	0.19	ADD1	adducin 1 (alpha)	26	0.98
chr9_505507_505658	0.18	KANK1	KN motif and ankyrin repeat domains 1	866	0.48
chr12_6570769_6570920	0.18	VAMP1	vesicle-associated membrane protein 1 (synaptobrevin 1)	8967	0.09
chr3_25705652_25705988	0.18	TOP2B	topoisomerase (DNA) II beta 180kDa	32	0.93
chr20_34204802_34205146	0.18	SPAG4	sperm associated antigen 4	28	0.96
chr11_27721482_27721925	0.18	BDNF	brain-derived neurotrophic factor	332	0.92
chr1_28199069_28199319	0.18	THEMIS2	thymocyte selection associated family member 2	115	0.94
chr19_13043739_13043983	0.18	FARSA	phenylalanyl-tRNA synthetase, alpha subunit	633	0.4
chr10_106028498_106028728	0.18	GSTO2	glutathione S-transferase omega 2	18	0.87
chr3_141121167_141121318	0.18	ZBTB38	zinc finger and BTB domain containing 38	30	0.98
chr8_19614612_19614805	0.18	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	108	0.98
chr18_60986734_60986955	0.18	BCL2	B-cell CLL/lymphoma 2	175	0.94
chr15_93277135_93277380	0.18	CTD-2313J17.5		47465	0.14
chrX_131352263_131353023	0.18	RAP2C-AS1	RAP2C antisense RNA 1	108	0.87
chr7_116502642_116502981	0.18	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	157	0.96
chr16_3355507_3355731	0.18	TIGD7	tigger transposable element derived 7	26	0.62
chr6_35464523_35464729	0.18	TEAD3	TEA domain family member 3	101	0.96
chr15_90809531_90809778	0.18	NGRN	neugrin, neurite outgrowth associated	717	0.53
chr4_154443229_154443447	0.18	KIAA0922	KIAA0922	33710	0.2
chr21_44465977_44466220	0.18	CBS	cystathionine-beta-synthase	12953	0.18
chr7_133537838_133538052	0.18	EXOC4	exocyst complex component 4	77277	0.12
chr6_33398954_33399253	0.18	SYNGAP1	synaptic Ras GTPase activating protein 1	405	0.74
chr5_78534794_78535305	0.18	JMY	junction mediating and regulatory protein, p53 cofactor	3037	0.24
chr12_54812006_54812311	0.18	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	1086	0.31
chr8_104383694_104384008	0.18	CTHRC1	collagen triple helix repeat containing 1	73	0.97
chr3_53279354_53279505	0.18	TKT	transketolase	10587	0.14
chr1_154317465_154317703	0.17	ENSG00000238365	.	6365	0.11
chrX_119125293_119125444	0.17	RP4-755D9.1		44833	0.1
chr1_206680885_206681199	0.17	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	163	0.93
chr7_99817647_99817839	0.17	ENSG00000222482	.	0	0.92
chr9_95730621_95730837	0.17	FGD3	FYVE, RhoGEF and PH domain containing 3	4486	0.25
chr16_30470345_30470503	0.17	ENSG00000202476	.	5006	0.07
chr1_202777207_202777594	0.17	KDM5B	lysine (K)-specific demethylase 5B	146	0.92
chr6_31543406_31543804	0.17	TNF	tumor necrosis factor	261	0.72
chr12_121678452_121678939	0.17	CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta	19650	0.17
chr13_52377985_52378296	0.17	DHRS12	dehydrogenase/reductase (SDR family) member 12	94	0.76
chr20_62695589_62695740	0.17	TCEA2	transcription elongation factor A (SII), 2	224	0.85
chr19_40939721_40939891	0.17	SERTAD1	SERTA domain containing 1	7874	0.1
chr15_100881107_100881338	0.17	ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	119	0.97
chr1_89591012_89591781	0.17	GBP2	guanylate binding protein 2, interferon-inducible	401	0.85
chr6_119215415_119215699	0.17	ASF1A	anti-silencing function 1A histone chaperone	173	0.96
chr9_34370936_34371111	0.17	KIAA1161	KIAA1161	1807	0.24
chr9_132221707_132221858	0.17	ENSG00000264298	.	19053	0.2
chr5_169715918_169716069	0.17	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	9238	0.23
chr3_127392819_127392970	0.17	ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	59	0.97
chr12_96793768_96794206	0.17	CDK17	cyclin-dependent kinase 17	135	0.96
chr7_99647395_99647894	0.17	ZSCAN21	zinc finger and SCAN domain containing 21	227	0.84
chr7_75157634_75157851	0.17	PMS2P3	postmeiotic segregation increased 2 pseudogene 3	603	0.67
chr3_152878430_152878675	0.17	RP11-529G21.2		1012	0.48
chr14_24014260_24014540	0.17	ZFHX2	zinc finger homeobox 2	3263	0.13
chr5_157078570_157078774	0.17	SOX30	SRY (sex determining region Y)-box 30	700	0.63
chr9_469822_470055	0.17	RP11-165F24.3		102	0.79
chr18_13464907_13465379	0.17	LDLRAD4	low density lipoprotein receptor class A domain containing 4	129	0.93
chr11_128386110_128386459	0.17	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	5812	0.25
chr12_116757459_116757895	0.17	MED13L	mediator complex subunit 13-like	42534	0.17
chr22_50987100_50987359	0.17	KLHDC7B	kelch domain containing 7B	767	0.36
chr2_208490362_208490613	0.17	METTL21A	methyltransferase like 21A	164	0.95
chr3_149375648_149375910	0.17	WWTR1	WW domain containing transcription regulator 1	33	0.73
chr1_202113559_202113734	0.17	ARL8A	ADP-ribosylation factor-like 8A	223	0.91
chr10_22610168_22610350	0.17	BMI1	BMI1 polycomb ring finger oncogene	119	0.95
chr4_24585686_24586088	0.17	DHX15	DEAH (Asp-Glu-Ala-His) box helicase 15	286	0.93
chr7_98741186_98741622	0.17	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	238	0.94
chr14_96000567_96000919	0.16	SNHG10	small nucleolar RNA host gene 10 (non-protein coding)	161	0.51
chr16_30197563_30197758	0.16	RP11-455F5.5		1382	0.19
chr12_132673421_132673572	0.16	GALNT9	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)	16841	0.18
chr1_149982315_149982703	0.16	OTUD7B	OTU domain containing 7B	115	0.96
chrX_152736458_152736643	0.16	HAUS7	HAUS augmin-like complex, subunit 7	461	0.46
chr19_1882294_1882445	0.16	ABHD17A	abhydrolase domain containing 17A	785	0.42
chr8_104033361_104033779	0.16	KB-1639H6.2		86	0.71
chr11_118938559_118938875	0.16	VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)	224	0.54
chr3_23245219_23245473	0.16	UBE2E2	ubiquitin-conjugating enzyme E2E 2	562	0.7
chr14_61747147_61747473	0.16	PRKCH	protein kinase C, eta	361	0.67
chrY_15591120_15591415	0.16	UTY	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	278	0.95
chr9_100880480_100880631	0.16	TRIM14	tripartite motif containing 14	925	0.6
chr17_1733308_1733656	0.16	RPA1	replication protein A1, 70kDa	204	0.43
chrX_49023399_49023590	0.16	MAGIX	MAGI family member, X-linked	2612	0.12
chr3_114112342_114112493	0.16	ZBTB20-AS1	ZBTB20 antisense RNA 1	5901	0.22
chr17_1358666_1358994	0.16	CRK	v-crk avian sarcoma virus CT10 oncogene homolog	613	0.67
chr22_17639891_17640083	0.16	CECR5	cat eye syndrome chromosome region, candidate 5	158	0.66
chr20_42840227_42840385	0.16	OSER1	oxidative stress responsive serine-rich 1	875	0.57
chr15_72766829_72767031	0.16	ARIH1	ariadne RBR E3 ubiquitin protein ligase 1	56	0.98
chr11_911061_911453	0.16	CHID1	chitinase domain containing 1	204	0.89
chr7_150864776_150864952	0.16	GBX1	gastrulation brain homeobox 1	229	0.88
chr18_24128072_24128256	0.16	KCTD1	potassium channel tetramerization domain containing 1	336	0.92
chr22_50050359_50050996	0.16	C22orf34	chromosome 22 open reading frame 34	401	0.87
chr11_105892671_105892946	0.16	MSANTD4	Myb/SANT-like DNA-binding domain containing 4 with coiled-coils	146	0.96
chr19_49255962_49256237	0.16	FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	2548	0.12
chr21_47743435_47743618	0.16	C21orf58	chromosome 21 open reading frame 58	245	0.71
chr12_120639128_120639290	0.16	PXN-AS1	PXN antisense RNA 1	35	0.67
chr10_51827733_51827958	0.16	FAM21A	family with sequence similarity 21, member A	124	0.97
chr4_184425406_184425681	0.16	RP11-367N14.2		104	0.89
chr3_148847432_148847663	0.16	HPS3	Hermansky-Pudlak syndrome 3	122	0.96
chr17_2496882_2497033	0.16	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	83	0.97
chr20_2673073_2673271	0.16	EBF4	early B-cell factor 4	352	0.77
chr3_128369380_128369595	0.16	RPN1	ribophorin I	205	0.95
chr2_11606375_11606585	0.16	E2F6	E2F transcription factor 6	205	0.92
chr7_97736267_97736674	0.16	LMTK2	lemur tyrosine kinase 2	273	0.93
chr12_49350271_49350454	0.16	ARF3	ADP-ribosylation factor 3	139	0.83
chr17_40896518_40896705	0.16	EZH1	enhancer of zeste homolog 1 (Drosophila)	437	0.67
chr2_10471479_10471715	0.16	HPCAL1	hippocalcin-like 1	27771	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.1	0.4	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.4	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.3	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	0.3	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1	0.3	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.3	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	0.2	GO:0001743	optic placode formation(GO:0001743)
0.1	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.2	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1	0.3	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.3	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.1	0.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.2	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.2	GO:0015809	arginine transport(GO:0015809)
0.1	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.1	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.2	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.6	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.2	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.3	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.3	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.2	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.2	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.2	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.1	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.3	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0006863	purine nucleobase transport(GO:0006863)
0.0	0.3	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.4	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.0	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.7	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.2	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.5	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.2	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.3	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.1	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579)
0.0	0.3	GO:0030149	sphingolipid catabolic process(GO:0030149)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.3	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.2	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.2	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0032069	regulation of nuclease activity(GO:0032069)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.0	GO:0046645	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.0	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.0	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:2000328	T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0090504	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.2	GO:0072676	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0090399	replicative senescence(GO:0090399)
0.0	0.2	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0014010	Schwann cell proliferation(GO:0014010)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.2	GO:0051322	anaphase(GO:0051322)
0.0	0.4	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0032607	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.0	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.2	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.0	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.0	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) regulation of membrane lipid distribution(GO:0097035)
0.0	0.0	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:1901070	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.0	0.3	GO:0051225	spindle assembly(GO:0051225)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.2	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0072666	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.0	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0	0.0	GO:0032527	retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.0	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.4	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.2	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.0	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.3	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.2	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.6	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.0	GO:0017004	cytochrome complex assembly(GO:0017004)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.3	GO:0030837	negative regulation of actin filament polymerization(GO:0030837)
0.0	0.0	GO:0006900	membrane budding(GO:0006900)
0.0	0.0	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	1.1	GO:0031497	nucleosome assembly(GO:0006334) chromatin assembly(GO:0031497)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.0	GO:0046629	gamma-delta T cell activation(GO:0046629)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.4	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.2	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.1	GO:0002209	behavioral defense response(GO:0002209)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.0	GO:0070193	synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0	0.0	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.3	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0006907	pinocytosis(GO:0006907)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.3	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.9	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.0	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.0	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.0	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.2	GO:0016236	macroautophagy(GO:0016236)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0032009	early phagosome(GO:0032009)
0.1	0.4	GO:0070820	tertiary granule(GO:0070820)
0.1	0.3	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.4	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.4	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.3	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.3	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.5	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.4	GO:0032420	stereocilium(GO:0032420)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.4	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.0	GO:0038201	TOR complex(GO:0038201)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.9	GO:0000786	nucleosome(GO:0000786)
0.0	0.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.0	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.9	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:1902555	endoribonuclease complex(GO:1902555)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0055037	recycling endosome(GO:0055037)
0.0	0.7	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.4	GO:0000922	spindle pole(GO:0000922)
0.0	0.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.0	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.4	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.8	GO:0005741	mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0035197	siRNA binding(GO:0035197)
0.1	0.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.4	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.3	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.1	0.2	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.5	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.3	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.3	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.2	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.3	GO:0071617	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.4	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.4	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.0	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.9	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.0	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.4	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.4	GO:0016830	carbon-carbon lyase activity(GO:0016830)
0.0	0.2	GO:0015929	hexosaminidase activity(GO:0015929)
0.0	0.2	GO:0015295	solute:proton symporter activity(GO:0015295)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.2	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.0	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.3	GO:0002020	protease binding(GO:0002020)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.7	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.8	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.9	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.6	PID ATR PATHWAY	ATR signaling pathway
0.0	0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.3	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.4	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.6	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.4	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.4	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.6	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions

Results for ZBTB6

Z-value: 0.92

Motif logo

Transcription factors associated with ZBTB6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ZBTB6 motif across conditions

Conditions sorted by the z-value of the ZBTB6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: