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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZFHX3

Z-value: 1.23

Motif logo

Transcription factors associated with ZFHX3

Gene Symbol	Gene ID	Gene Info
ZFHX3 Ensembl NCBI GeneCards UniProt	ENSG00000140836.10	ZFHX3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZFHX3	chr16_73088507_73088710	4989	0.255734	-0.87	2.2e-03	Click!
ZFHX3	chr16_73086572_73086723	4373	0.262989	-0.80	8.9e-03	Click!
ZFHX3	chr16_73105015_73105287	11554	0.234841	-0.76	1.7e-02	Click!
ZFHX3	chr16_73102617_73102909	9166	0.240506	-0.72	2.8e-02	Click!
ZFHX3	chr16_73093289_73093448	229	0.948003	-0.72	2.8e-02	Click!

Activity of the ZFHX3 motif across conditions

Conditions sorted by the z-value of the ZFHX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_20336872_20337023	0.68	E2F3	E2F transcription factor 3	65451	0.1
chr8_134086469_134086645	0.66	SLA	Src-like-adaptor	13954	0.23
chr2_61111507_61111691	0.66	REL	v-rel avian reticuloendotheliosis viral oncogene homolog	2808	0.27
chr7_150414678_150414897	0.63	GIMAP1	GTPase, IMAP family member 1	1142	0.45
chr8_126960676_126960849	0.59	ENSG00000206695	.	47567	0.2
chr5_40686354_40686614	0.58	PTGER4	prostaglandin E receptor 4 (subtype EP4)	6884	0.22
chrX_78400540_78401325	0.56	GPR174	G protein-coupled receptor 174	25537	0.27
chrX_146273220_146273371	0.55	ENSG00000216171	.	1990	0.19
chrX_84258496_84258805	0.55	APOOL	apolipoprotein O-like	182	0.97
chrX_22878429_22878580	0.52	DDX53	DEAD (Asp-Glu-Ala-Asp) box polypeptide 53	139583	0.05
chr3_24225373_24225524	0.51	THRB	thyroid hormone receptor, beta	18362	0.28
chr14_22968352_22968523	0.48	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	12266	0.1
chr15_60883034_60883482	0.47	RORA	RAR-related orphan receptor A	1482	0.47
chrX_37910743_37910894	0.47	SYTL5	synaptotagmin-like 5	18031	0.2
chr5_67576888_67577103	0.45	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	860	0.74
chr9_33446798_33447442	0.44	AQP3	aquaporin 3 (Gill blood group)	489	0.76
chr4_122148073_122148224	0.44	TNIP3	TNFAIP3 interacting protein 3	473	0.85
chr5_119523820_119523971	0.43	ENSG00000251975	.	149453	0.05
chr9_134151798_134152108	0.42	FAM78A	family with sequence similarity 78, member A	19	0.98
chr7_142430842_142430993	0.42	PRSS1	protease, serine, 1 (trypsin 1)	26402	0.17
chr14_71455264_71455741	0.42	PCNX	pecanex homolog (Drosophila)	24246	0.26
chr19_54465805_54465956	0.40	CACNG8	calcium channel, voltage-dependent, gamma subunit 8	414	0.72
chr13_41540610_41540946	0.40	ELF1	E74-like factor 1 (ets domain transcription factor)	15640	0.18
chr14_100689805_100690076	0.40	YY1	YY1 transcription factor	14695	0.11
chr9_34745557_34745708	0.39	FAM205A	family with sequence similarity 205, member A	16168	0.13
chr1_113164228_113164419	0.39	ST7L	suppression of tumorigenicity 7 like	2283	0.19
chr14_22947593_22947744	0.38	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	2372	0.15
chr1_200865204_200865355	0.38	C1orf106	chromosome 1 open reading frame 106	1330	0.42
chr1_247333614_247333765	0.38	ZNF124	zinc finger protein 124	1580	0.32
chr11_89271457_89271608	0.38	NOX4	NADPH oxidase 4	40177	0.2
chr1_33447039_33447276	0.38	RP1-117O3.2		5519	0.15
chr12_22565647_22565798	0.37	C2CD5	C2 calcium-dependent domain containing 5	59517	0.14
chr4_48134207_48134444	0.37	TXK	TXK tyrosine kinase	1948	0.29
chr11_118213949_118214100	0.36	CD3D	CD3d molecule, delta (CD3-TCR complex)	565	0.54
chr6_128221212_128221624	0.36	THEMIS	thymocyte selection associated	685	0.81
chr1_25889724_25889930	0.36	LDLRAP1	low density lipoprotein receptor adaptor protein 1	19756	0.18
chr2_191225245_191225396	0.36	INPP1	inositol polyphosphate-1-phosphatase	4058	0.23
chr8_115225029_115225180	0.35	ENSG00000206719	.	261989	0.02
chr3_33061626_33061777	0.35	CCR4	chemokine (C-C motif) receptor 4	68635	0.09
chr6_24929304_24929455	0.34	FAM65B	family with sequence similarity 65, member B	6809	0.24
chr18_56326442_56326593	0.34	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	12101	0.14
chr8_17782406_17782557	0.34	PCM1	pericentriolar material 1	228	0.93
chr11_95420136_95420287	0.34	FAM76B	family with sequence similarity 76, member B	99758	0.08
chr12_47611625_47611801	0.34	PCED1B	PC-esterase domain containing 1B	1332	0.49
chr12_69724195_69724437	0.34	LYZ	lysozyme	17805	0.16
chr6_106969102_106969411	0.33	AIM1	absent in melanoma 1	9526	0.21
chr12_76271082_76271233	0.33	ENSG00000243420	.	80753	0.1
chr11_128387324_128387802	0.32	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	4533	0.26
chr17_29645805_29646348	0.32	CTD-2370N5.3		227	0.88
chr1_158903283_158903483	0.32	PYHIN1	pyrin and HIN domain family, member 1	2025	0.36
chr17_75453810_75454179	0.32	SEPT9	septin 9	1546	0.33
chr5_39203281_39203432	0.32	FYB	FYN binding protein	227	0.96
chr19_4535398_4535574	0.31	PLIN5	perilipin 5	250	0.84
chr20_18446613_18446764	0.31	DZANK1	double zinc ribbon and ankyrin repeat domains 1	663	0.48
chr1_160611595_160611756	0.31	SLAMF1	signaling lymphocytic activation molecule family member 1	5136	0.18
chr6_128239129_128239316	0.31	THEMIS	thymocyte selection associated	463	0.89
chr6_26198173_26198564	0.31	HIST1H3D	histone cluster 1, H3d	890	0.22
chr1_65428751_65428968	0.31	JAK1	Janus kinase 1	3328	0.31
chr3_16347363_16347514	0.31	RP11-415F23.2		8508	0.17
chr9_135038389_135038692	0.31	NTNG2	netrin G2	1206	0.56
chr3_66549418_66550156	0.31	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	1569	0.56
chr20_43597999_43598419	0.31	STK4	serine/threonine kinase 4	3042	0.19
chr1_24862040_24862255	0.31	ENSG00000266551	.	5943	0.18
chrX_78621479_78621720	0.31	ITM2A	integral membrane protein 2A	1257	0.64
chr1_38461172_38461323	0.31	ENSG00000212541	.	4113	0.14
chr3_46413606_46413757	0.31	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	480	0.77
chr12_118796743_118797337	0.31	TAOK3	TAO kinase 3	69	0.98
chr1_100573281_100573432	0.31	RP4-714D9.2		23329	0.12
chr13_69182775_69182926	0.31	ENSG00000243671	.	85363	0.11
chr18_34410889_34411040	0.30	KIAA1328	KIAA1328	1673	0.34
chr16_4538279_4538430	0.30	HMOX2	heme oxygenase (decycling) 2	7505	0.13
chr19_2819518_2819756	0.29	ZNF554	zinc finger protein 554	235	0.87
chr13_41553714_41553865	0.29	ELF1	E74-like factor 1 (ets domain transcription factor)	2629	0.29
chr1_7946262_7946413	0.29	UTS2	urotensin 2	32765	0.14
chr6_139352039_139352190	0.29	ABRACL	ABRA C-terminal like	2135	0.38
chr12_8240325_8240677	0.29	NECAP1	NECAP endocytosis associated 1	5118	0.16
chr2_197127548_197127913	0.29	AC020571.3		2573	0.29
chr2_55236798_55237891	0.29	RTN4	reticulon 4	241	0.93
chr3_141249287_141249763	0.29	RASA2-IT1	RASA2 intronic transcript 1 (non-protein coding)	5550	0.26
chr2_242051303_242051464	0.28	MTERFD2	MTERF domain containing 2	9636	0.14
chr6_144668099_144668390	0.28	UTRN	utrophin	3007	0.32
chr1_206731858_206732141	0.28	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	1506	0.37
chr12_18841597_18841748	0.28	PLCZ1	phospholipase C, zeta 1	6299	0.25
chr5_156609776_156609927	0.28	ITK	IL2-inducible T-cell kinase	2014	0.23
chr11_124665951_124666102	0.28	MSANTD2	Myb/SANT-like DNA-binding domain containing 2	4253	0.12
chr6_154570961_154571273	0.28	IPCEF1	interaction protein for cytohesin exchange factors 1	2301	0.45
chr10_17548651_17548924	0.28	ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	52458	0.13
chr8_82020312_82020466	0.27	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	3914	0.34
chr4_90220151_90220996	0.27	GPRIN3	GPRIN family member 3	8588	0.31
chr10_8099034_8099185	0.27	GATA3	GATA binding protein 3	2340	0.45
chr18_12847485_12847636	0.27	PTPN2	protein tyrosine phosphatase, non-receptor type 2	3580	0.29
chr10_119891870_119892021	0.27	CASC2	cancer susceptibility candidate 2 (non-protein coding)	82820	0.09
chr4_93156215_93156366	0.27	RP11-9B6.1	HCG2045747; Uncharacterized protein	69039	0.13
chr13_46755773_46755938	0.27	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	604	0.7
chr8_100795778_100795929	0.27	RP11-402L5.1		15562	0.25
chr16_89551290_89551568	0.27	ANKRD11	ankyrin repeat domain 11	5297	0.13
chr1_192547268_192547419	0.26	RGS1	regulator of G-protein signaling 1	2440	0.31
chrX_84632426_84632577	0.26	POF1B	premature ovarian failure, 1B	2221	0.45
chr1_109188702_109189117	0.26	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)	14768	0.19
chrX_118926003_118926336	0.26	RPL39	ribosomal protein L39	563	0.7
chr8_38243294_38243670	0.26	LETM2	leucine zipper-EF-hand containing transmembrane protein 2	243	0.88
chr3_151917198_151917573	0.26	MBNL1	muscleblind-like splicing regulator 1	68444	0.12
chr11_47787507_47787658	0.26	FNBP4	formin binding protein 4	1271	0.36
chr1_84611671_84611822	0.25	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	1792	0.48
chr7_35731550_35731936	0.25	HERPUD2	HERPUD family member 2	2433	0.31
chrY_8388065_8388216	0.25	AC007967.3		386125	0.01
chr6_149729706_149729857	0.25	SUMO4	small ubiquitin-like modifier 4	8286	0.19
chr2_31547763_31547914	0.25	XDH	xanthine dehydrogenase	89743	0.08
chr11_128385412_128385563	0.25	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	6609	0.25
chr11_16946345_16946496	0.25	PLEKHA7	pleckstrin homology domain containing, family A member 7	43515	0.12
chr3_63954713_63955178	0.25	ATXN7	ataxin 7	1525	0.34
chr7_138788856_138789199	0.25	ZC3HAV1	zinc finger CCCH-type, antiviral 1	5073	0.23
chr2_223290336_223290619	0.24	SGPP2	sphingosine-1-phosphate phosphatase 2	1241	0.5
chr4_109086470_109087224	0.24	LEF1	lymphoid enhancer-binding factor 1	610	0.72
chr9_36152272_36152423	0.24	GLIPR2	GLI pathogenesis-related 2	15605	0.17
chr1_198654198_198654380	0.24	RP11-553K8.5		18099	0.24
chr8_52771885_52772036	0.24	PCMTD1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	13655	0.18
chr1_116293768_116293919	0.24	CASQ2	calsequestrin 2 (cardiac muscle)	17492	0.24
chr3_168234505_168234656	0.24	ENSG00000207717	.	35062	0.2
chr5_40678072_40678223	0.23	PTGER4	prostaglandin E receptor 4 (subtype EP4)	1453	0.44
chr7_38343163_38343314	0.23	STARD3NL	STARD3 N-terminal like	125241	0.06
chr17_47766049_47766200	0.23	SPOP	speckle-type POZ protein	10528	0.14
chr3_186743992_186744192	0.23	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	821	0.7
chr8_82022969_82023806	0.23	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	916	0.72
chr3_29395618_29395769	0.23	ENSG00000216169	.	15219	0.25
chr11_2405249_2405453	0.23	CD81	CD81 molecule	529	0.65
chr8_8706094_8706267	0.23	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	44975	0.14
chr5_118606441_118606592	0.23	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2067	0.32
chr8_103802665_103802816	0.23	ENSG00000266799	.	56793	0.11
chr19_925725_925912	0.23	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	182	0.87
chr7_153247150_153247301	0.23	DPP6	dipeptidyl-peptidase 6	336957	0.01
chr3_47822404_47822881	0.23	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	765	0.62
chr6_2970743_2970993	0.23	SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6	572	0.7
chr16_75836248_75836399	0.23	ENSG00000199299	.	58732	0.12
chr13_99909205_99909490	0.23	GPR18	G protein-coupled receptor 18	1281	0.47
chr4_123820303_123820454	0.22	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	14065	0.17
chr5_88161245_88161396	0.22	MEF2C	myocyte enhancer factor 2C	12474	0.24
chr22_43315092_43315243	0.22	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	26712	0.19
chr1_93646822_93647050	0.22	TMED5	transmembrane emp24 protein transport domain containing 5	651	0.44
chr4_17615953_17616129	0.22	AC006160.5		153	0.58
chr19_2562414_2562565	0.22	CTC-265F19.2		49371	0.09
chr15_60882704_60882968	0.22	RORA	RAR-related orphan receptor A	1904	0.39
chr10_677138_677289	0.22	RP11-809C18.3		2635	0.23
chr17_26697729_26697880	0.22	VTN	vitronectin	39	0.9
chr11_71934379_71934736	0.22	INPPL1	inositol polyphosphate phosphatase-like 1	188	0.89
chr1_192776419_192777001	0.22	RGS2	regulator of G-protein signaling 2, 24kDa	1461	0.52
chr5_55290006_55290408	0.22	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	585	0.51
chr2_198064152_198064348	0.22	ANKRD44	ankyrin repeat domain 44	1488	0.35
chr1_197167037_197167371	0.22	ZBTB41	zinc finger and BTB domain containing 41	2468	0.29
chr15_60881660_60881911	0.22	RORA	RAR-related orphan receptor A	2955	0.3
chr16_18957307_18957806	0.22	ENSG00000265515	.	15952	0.13
chr14_50160138_50160409	0.22	KLHDC1	kelch domain containing 1	426	0.71
chr2_220113848_220114166	0.22	STK16	serine/threonine kinase 16	3389	0.09
chr1_114413652_114413958	0.21	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	515	0.69
chr18_55298168_55298387	0.21	RP11-35G9.3		695	0.64
chr6_152505938_152506206	0.21	SYNE1	spectrin repeat containing, nuclear envelope 1	16573	0.28
chr5_67577155_67577306	0.21	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	1095	0.66
chr1_19717605_19717920	0.21	CAPZB	capping protein (actin filament) muscle Z-line, beta	5471	0.18
chr6_135545194_135545568	0.21	ENSG00000207689	.	14917	0.16
chr12_69007685_69008546	0.21	RAP1B	RAP1B, member of RAS oncogene family	3310	0.27
chr20_31099035_31099434	0.21	C20orf112	chromosome 20 open reading frame 112	24	0.98
chr7_150264558_150265605	0.21	GIMAP4	GTPase, IMAP family member 4	557	0.78
chr5_159898654_159898805	0.21	ENSG00000265237	.	2680	0.24
chr14_57283183_57283334	0.21	OTX2-AS1	OTX2 antisense RNA 1 (head to head)	3249	0.2
chr12_10328213_10328364	0.21	TMEM52B	transmembrane protein 52B	3324	0.16
chr14_102278905_102279056	0.21	CTD-2017C7.2		2322	0.22
chr7_21472009_21472160	0.21	SP4	Sp4 transcription factor	4423	0.22
chr12_93834472_93834763	0.21	UBE2N	ubiquitin-conjugating enzyme E2N	415	0.81
chr13_46755018_46755169	0.21	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	1366	0.39
chr14_22994017_22994177	0.20	TRAJ15	T cell receptor alpha joining 15	4483	0.13
chr1_84610455_84610717	0.20	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	632	0.82
chr10_53873012_53873163	0.20	PRKG1	protein kinase, cGMP-dependent, type I	66550	0.14
chr12_53781982_53782414	0.20	SP1	Sp1 transcription factor	7112	0.13
chr3_183947999_183948171	0.20	VWA5B2	von Willebrand factor A domain containing 5B2	132	0.92
chr5_143571495_143571743	0.20	KCTD16	potassium channel tetramerization domain containing 16	13221	0.22
chr8_135697544_135697755	0.20	ZFAT	zinc finger and AT hook domain containing	11148	0.28
chr3_95425254_95425405	0.20	ENSG00000221477	.	460417	0.01
chr6_129828990_129829141	0.20	RP1-69D17.3		26510	0.24
chr14_61809095_61809246	0.20	PRKCH	protein kinase C, eta	1790	0.38
chr5_81074467_81075538	0.20	SSBP2	single-stranded DNA binding protein 2	27930	0.25
chr5_56794860_56795362	0.20	ACTBL2	actin, beta-like 2	16475	0.22
chr15_101780403_101780609	0.20	CHSY1	chondroitin sulfate synthase 1	11631	0.18
chr13_92500241_92500392	0.20	ENSG00000252508	.	211781	0.03
chr12_31957451_31957616	0.20	ENSG00000252421	.	1509	0.36
chr20_48381612_48381763	0.20	ENSG00000252540	.	29661	0.13
chr6_149663878_149664029	0.20	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	21765	0.18
chrX_78417981_78418132	0.20	GPR174	G protein-coupled receptor 174	8413	0.33
chr13_30419313_30419464	0.20	UBL3	ubiquitin-like 3	5433	0.32
chrX_26102260_26102411	0.20	MAGEB18	melanoma antigen family B, 18	54125	0.17
chr2_32390112_32390263	0.20	SLC30A6	solute carrier family 30 (zinc transporter), member 6	746	0.69
chr14_102276711_102277223	0.19	CTD-2017C7.2		309	0.73
chr1_38858671_38858822	0.19	ENSG00000200796	.	3585	0.36
chr3_63964903_63965338	0.19	ATXN7	ataxin 7	11700	0.14
chr5_20958214_20958365	0.19	CDH18	cadherin 18, type 2	382307	0.01
chr7_55842183_55842464	0.19	ENSG00000206729	.	14738	0.2
chr1_86315709_86315987	0.19	ENSG00000201620	.	33633	0.23
chr14_22342431_22342583	0.19	ENSG00000222776	.	93722	0.08
chr5_102295026_102295177	0.19	PAM	peptidylglycine alpha-amidating monooxygenase	9820	0.31
chr5_73932696_73932847	0.19	HEXB	hexosaminidase B (beta polypeptide)	3077	0.26
chr6_111801598_111801749	0.19	REV3L	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	2741	0.26

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0070295	renal water absorption(GO:0070295)
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	1.1	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.3	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.4	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.2	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.2	GO:0042510	regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510) positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.2	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.2	GO:2000351	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.3	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.4	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0050856	regulation of T cell receptor signaling pathway(GO:0050856)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.9	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0034311	diol metabolic process(GO:0034311)
0.0	0.0	GO:0002902	regulation of B cell apoptotic process(GO:0002902)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043370) regulation of CD4-positive, alpha-beta T cell activation(GO:2000514)
0.0	0.3	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.1	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.0	0.0	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0033866	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.0	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0	0.0	GO:0070266	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.3	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.4	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.3	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.0	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0046030	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.0	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID IL5 PATHWAY	IL5-mediated signaling events
0.4	PID IL3 PATHWAY	IL3-mediated signaling events
1.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.0	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.1	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.0	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex