Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for ZIC1

Z-value: 1.28

Motif logo

logo of

Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ZIC1
ENSG00000152977.5 Zic family member 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_147131973_147132124ZIC148770.2088150.844.2e-03Click!
chr3_147126089_147126240ZIC110070.4507910.835.3e-03Click!
chr3_147142704_147142855ZIC1156080.1866110.826.9e-03Click!
chr3_147115262_147115580ZIC137390.2101340.818.5e-03Click!
chr3_147111194_147111421ZIC13750.8508740.809.0e-03Click!

Activity of the ZIC1 motif across conditions

Conditions sorted by the z-value of the ZIC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_108520152_108520684 0.81 FAM155A
 family with sequence similarity 155, member A
 1335
 0.55
chr17_75317825_75318000 0.80 SEPT9
 septin 9
 780
 0.69
chr10_110225810_110226152 0.79 ENSG00000222436
 .
 475087
 0.01
chr2_158113918_158114875 0.72 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
 286
 0.93
chr12_81102183_81102935 0.67 MYF6
 myogenic factor 6 (herculin)
 1282
 0.49
chr8_126013201_126013598 0.66 SQLE
 squalene epoxidase
 2613
 0.23
chr6_123110376_123110857 0.64 SMPDL3A
 sphingomyelin phosphodiesterase, acid-like 3A
 145
 0.96
chr9_12776208_12776436 0.63 LURAP1L
 leucine rich adaptor protein 1-like
 1302
 0.47
chr2_142887906_142888379 0.62 LRP1B
 low density lipoprotein receptor-related protein 1B
 432
 0.87
chr2_27301899_27302732 0.61 EMILIN1
 elastin microfibril interfacer 1
 880
 0.32
chr9_8857014_8857547 0.59 PTPRD
 protein tyrosine phosphatase, receptor type, D
 496
 0.84
chr17_29887299_29887674 0.58 ENSG00000207614
 .
 471
 0.69
chr4_113739356_113739869 0.57 ANK2
 ankyrin 2, neuronal
 347
 0.9
chr6_48037118_48037375 0.57 PTCHD4
 patched domain containing 4
 821
 0.78
chr2_235862821_235863118 0.55 SH3BP4
 SH3-domain binding protein 4
 2249
 0.48
chr6_12292037_12292313 0.55 EDN1
 endothelin 1
 1579
 0.54
chrX_8699533_8700279 0.54 KAL1
 Kallmann syndrome 1 sequence
 321
 0.94
chr15_101513524_101514094 0.54 LRRK1
 leucine-rich repeat kinase 1
 54259
 0.12
chr12_110993281_110993585 0.53 PPTC7
 PTC7 protein phosphatase homolog (S. cerevisiae)
 27692
 0.12
chr20_34471632_34471916 0.52 ENSG00000201221
 .
 3807
 0.18
chrX_117250265_117250710 0.51 KLHL13
 kelch-like family member 13
 274
 0.95
chrX_151142056_151142353 0.50 GABRE
 gamma-aminobutyric acid (GABA) A receptor, epsilon
 939
 0.49
chr22_46454527_46455045 0.50 RP6-109B7.3
3991
 0.12
chr3_9989057_9989268 0.50 PRRT3-AS1
 PRRT3 antisense RNA 1
 74
 0.93
chr5_73729921_73730212 0.49 ENSG00000244326
 .
 116255
 0.06
chr5_166406240_166406516 0.48 TENM2
 teneurin transmembrane protein 2
 305426
 0.01
chr3_87040086_87040946 0.48 VGLL3
 vestigial like 3 (Drosophila)
 247
 0.96
chr8_127837007_127837644 0.48 ENSG00000212451
 .
 153558
 0.04
chr7_127899527_127899678 0.48 LEP
 leptin
 18265
 0.16
chr4_106816123_106816518 0.48 NPNT
 nephronectin
 274
 0.81
chr19_51161641_51162497 0.47 C19orf81
 chromosome 19 open reading frame 81
 9024
 0.12
chr9_130341109_130341430 0.47 FAM129B
 family with sequence similarity 129, member B
 1
 0.98
chr2_149894818_149895436 0.47 LYPD6B
 LY6/PLAUR domain containing 6B
 105
 0.98
chr14_71022448_71023169 0.47 ADAM20
 ADAM metallopeptidase domain 20
 21076
 0.17
chr4_175750179_175750687 0.46 GLRA3
 glycine receptor, alpha 3
 32
 0.99
chr20_9049976_9050220 0.46 PLCB4
 phospholipase C, beta 4
 350
 0.89
chr10_34815325_34815760 0.45 PARD3
 par-3 family cell polarity regulator
 99883
 0.09
chr6_166075279_166075470 0.45 PDE10A
 phosphodiesterase 10A
 183
 0.97
chr1_16472641_16472879 0.45 RP11-276H7.2
8946
 0.12
chr3_8809480_8810320 0.44 OXTR
 oxytocin receptor
 463
 0.76
chr13_30157377_30157646 0.44 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 3418
 0.36
chr9_23821130_23821679 0.44 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
 74
 0.99
chr17_28667391_28667637 0.44 ENSG00000207132
 .
 4108
 0.15
chr10_6443642_6443853 0.44 DKFZP667F0711
51469
 0.16
chr19_14605464_14605615 0.44 GIPC1
 GIPC PDZ domain containing family, member 1
 1405
 0.26
chr2_10526122_10526400 0.44 HPCAL1
 hippocalcin-like 1
 33886
 0.15
chr14_89769991_89770787 0.44 RP11-356K23.1
46240
 0.14
chr7_116660327_116660575 0.43 ST7
 suppression of tumorigenicity 7
 120
 0.96
chr12_56075239_56075869 0.42 METTL7B
 methyltransferase like 7B
 224
 0.86
chr5_92908415_92908864 0.42 ENSG00000237187
 .
 1590
 0.42
chr1_1283171_1284080 0.42 DVL1
 dishevelled segment polarity protein 1
 867
 0.32
chr8_41165761_41166040 0.42 SFRP1
 secreted frizzled-related protein 1
 1116
 0.48
chr4_138974934_138975159 0.42 ENSG00000250033
 .
 3572
 0.39
chr6_10383738_10384217 0.42 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
 20850
 0.18
chr12_54676753_54676980 0.42 HNRNPA1
 heterogeneous nuclear ribonucleoprotein A1
 884
 0.34
chr1_33367226_33367525 0.41 TMEM54
 transmembrane protein 54
 385
 0.8
chr9_102591075_102591263 0.41 NR4A3
 nuclear receptor subfamily 4, group A, member 3
 2160
 0.4
chr11_77733968_77734525 0.41 KCTD14
 potassium channel tetramerization domain containing 14
 94
 0.72
chr6_4369736_4370097 0.41 ENSG00000201185
 .
 58281
 0.15
chr3_123476244_123476543 0.40 MYLK
 myosin light chain kinase
 36295
 0.15
chr1_170633420_170634117 0.40 PRRX1
 paired related homeobox 1
 690
 0.8
chr2_153193063_153193456 0.40 FMNL2
 formin-like 2
 1508
 0.52
chr20_47299051_47299422 0.40 ENSG00000251876
 .
 56749
 0.16
chr6_76234416_76234599 0.40 FILIP1
 filamin A interacting protein 1
 31053
 0.15
chr7_93550787_93551002 0.40 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
 117
 0.96
chr1_109490979_109491171 0.40 CLCC1
 chloride channel CLIC-like 1
 1985
 0.29
chr1_153581254_153581448 0.40 S100A16
 S100 calcium binding protein A16
 462
 0.62
chr9_132096752_132097176 0.40 ENSG00000242281
 .
 35776
 0.16
chr11_122028989_122029168 0.40 ENSG00000207994
 .
 6062
 0.18
chr8_94859053_94859497 0.40 TMEM67
 transmembrane protein 67
 61778
 0.09
chr11_61685093_61685479 0.39 RAB3IL1
 RAB3A interacting protein (rabin3)-like 1
 289
 0.85
chr2_176931780_176932252 0.39 EVX2
 even-skipped homeobox 2
 16625
 0.1
chr1_201430589_201431038 0.39 PHLDA3
 pleckstrin homology-like domain, family A, member 3
 7499
 0.16
chr5_33891538_33892159 0.39 ADAMTS12
 ADAM metallopeptidase with thrombospondin type 1 motif, 12
 198
 0.94
chr2_216296824_216297216 0.38 FN1
 fibronectin 1
 3770
 0.26
chr11_122046887_122047202 0.38 ENSG00000207994
 .
 24028
 0.16
chr18_53087556_53087938 0.38 TCF4
 transcription factor 4
 1839
 0.39
chr1_13910795_13911459 0.38 PDPN
 podoplanin
 362
 0.87
chr11_131416298_131416516 0.38 AP003025.2
5646
 0.24
chr2_85632386_85633119 0.38 CAPG
 capping protein (actin filament), gelsolin-like
 3186
 0.11
chr11_2949356_2950534 0.38 PHLDA2
 pleckstrin homology-like domain, family A, member 2
 740
 0.54
chr4_38121545_38121863 0.38 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 74212
 0.12
chr1_60031328_60031726 0.38 FGGY
 FGGY carbohydrate kinase domain containing
 11937
 0.3
chr19_52222495_52223170 0.38 HAS1
 hyaluronan synthase 1
 110
 0.94
chr10_25155972_25156509 0.38 ENSG00000240294
 .
 41501
 0.18
chr2_1711742_1712354 0.38 PXDN
 peroxidasin homolog (Drosophila)
 15706
 0.26
chr11_8832007_8832297 0.37 ST5
 suppression of tumorigenicity 5
 44
 0.97
chr9_94710782_94711296 0.37 ROR2
 receptor tyrosine kinase-like orphan receptor 2
 123
 0.98
chr2_63893254_63893651 0.37 ENSG00000221085
 .
 29217
 0.21
chr7_83278228_83278460 0.37 SEMA3E
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
 18
 0.99
chr1_65774988_65775539 0.37 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
 35
 0.98
chr2_196978205_196978455 0.37 RP11-347P5.1
37657
 0.15
chr7_117512754_117513170 0.37 CTTNBP2
 cortactin binding protein 2
 599
 0.85
chr3_134088468_134088746 0.36 AMOTL2
 angiomotin like 2
 2147
 0.35
chr20_8112947_8113200 0.36 PLCB1
 phospholipase C, beta 1 (phosphoinositide-specific)
 199
 0.97
chr20_10651235_10651457 0.36 RP11-103J8.1
2230
 0.35
chr11_65259449_65259600 0.36 SCYL1
 SCY1-like 1 (S. cerevisiae)
 33024
 0.08
chr14_100204021_100204271 0.36 EML1
 echinoderm microtubule associated protein like 1
 60
 0.98
chr7_90084746_90084920 0.36 CDK14
 cyclin-dependent kinase 14
 10905
 0.23
chr3_45241366_45241603 0.36 TMEM158
 transmembrane protein 158 (gene/pseudogene)
 26286
 0.18
chr19_13136060_13136211 0.36 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 324
 0.8
chr8_495850_496251 0.36 TDRP
 testis development related protein
 269
 0.95
chrX_153595297_153595831 0.36 FLNA
 filamin A, alpha
 4087
 0.1
chr7_89841494_89841721 0.35 STEAP2
 STEAP family member 2, metalloreductase
 362
 0.65
chr14_85707273_85707789 0.35 ENSG00000252529
 .
 30745
 0.26
chr1_112933403_112933636 0.35 CTTNBP2NL
 CTTNBP2 N-terminal like
 5284
 0.23
chr1_44300309_44300553 0.35 ST3GAL3
 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
 64829
 0.09
chr6_38230060_38230313 0.35 ENSG00000200706
 .
 55136
 0.16
chr12_77625749_77626115 0.35 ENSG00000238769
 .
 69127
 0.14
chr2_181559754_181559963 0.34 ENSG00000264976
 .
 77925
 0.12
chr9_35341457_35341792 0.34 AL160274.1
 HCG17281; PRO0038; Uncharacterized protein
 19638
 0.2
chr3_64670816_64671530 0.34 ADAMTS9-AS2
 ADAMTS9 antisense RNA 2
 369
 0.87
chr6_27205685_27206711 0.34 PRSS16
 protease, serine, 16 (thymus)
 9282
 0.19
chr4_74735225_74735723 0.34 CXCL1
 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
 353
 0.85
chr5_176899210_176899576 0.34 DBN1
 drebrin 1
 478
 0.65
chr2_79739509_79740065 0.34 CTNNA2
 catenin (cadherin-associated protein), alpha 2
 339
 0.91
chr19_48016527_48016998 0.34 NAPA
 N-ethylmaleimide-sensitive factor attachment protein, alpha
 703
 0.59
chr10_52834229_52834739 0.33 PRKG1
 protein kinase, cGMP-dependent, type I
 550
 0.81
chr17_74536772_74536989 0.33 PRCD
 progressive rod-cone degeneration
 708
 0.43
chr5_2752991_2753357 0.33 C5orf38
 chromosome 5 open reading frame 38
 795
 0.6
chr22_30601263_30601429 0.33 RP3-438O4.4
1752
 0.27
chr6_130450991_130451225 0.33 RP11-73O6.3
8233
 0.25
chr3_23713475_23713674 0.33 ENSG00000212269
 .
 30491
 0.19
chr1_33207592_33208218 0.32 KIAA1522
 KIAA1522
 419
 0.8
chr7_36195246_36195841 0.32 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 2666
 0.32
chr1_167789688_167789943 0.32 RP1-313L4.3
171
 0.96
chr20_46412966_46413363 0.32 SULF2
 sulfatase 2
 1069
 0.59
chr12_113683537_113683756 0.32 TPCN1
 two pore segment channel 1
 1473
 0.33
chr18_421335_421729 0.32 RP11-720L2.2
2884
 0.33
chr2_218714763_218715120 0.32 TNS1
 tensin 1
 8058
 0.27
chr18_8948520_8948699 0.32 RP11-674N23.4
146955
 0.04
chr7_84815825_84816071 0.31 SEMA3D
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
 223
 0.97
chr14_96671190_96671644 0.31 RP11-404P21.8
 Uncharacterized protein
 236
 0.48
chr3_42113480_42113939 0.31 TRAK1
 trafficking protein, kinesin binding 1
 18853
 0.25
chr11_57267285_57267491 0.31 SLC43A1
 solute carrier family 43 (amino acid system L transporter), member 1
 1404
 0.25
chr22_31198410_31198813 0.31 OSBP2
 oxysterol binding protein 2
 462
 0.84
chr20_55800377_55800528 0.31 RP4-813D12.2
10524
 0.2
chr2_37870062_37870489 0.31 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
 4526
 0.29
chr16_75284494_75285397 0.31 BCAR1
 breast cancer anti-estrogen resistance 1
 100
 0.96
chr16_65154751_65155029 0.30 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 943
 0.75
chr19_9473504_9474272 0.30 ZNF177
 zinc finger protein 177
 181
 0.93
chr5_1494740_1494891 0.30 LPCAT1
 lysophosphatidylcholine acyltransferase 1
 29277
 0.18
chr10_77155014_77155181 0.30 ENSG00000237149
 .
 6180
 0.2
chr5_136481655_136482067 0.30 SPOCK1
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
 167366
 0.04
chr9_130860823_130861938 0.30 SLC25A25
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
 544
 0.57
chr7_101268427_101268664 0.30 MYL10
 myosin, light chain 10, regulatory
 4031
 0.33
chr17_71287404_71287786 0.30 CDC42EP4
 CDC42 effector protein (Rho GTPase binding) 4
 19952
 0.15
chr12_5541333_5541550 0.30 NTF3
 neurotrophin 3
 162
 0.98
chr1_216773992_216774229 0.30 ESRRG
 estrogen-related receptor gamma
 122564
 0.06
chr8_66861458_66861787 0.29 DNAJC5B
 DnaJ (Hsp40) homolog, subfamily C, member 5 beta
 72173
 0.12
chr6_47666429_47666580 0.29 GPR115
 G protein-coupled receptor 115
 215
 0.94
chrX_17395960_17396111 0.29 NHS
 Nance-Horan syndrome (congenital cataracts and dental anomalies)
 2492
 0.32
chr4_184797459_184798247 0.29 STOX2
 storkhead box 2
 28656
 0.22
chr6_143605233_143605462 0.29 AL031320.1
154228
 0.03
chr2_205410516_205411018 0.29 PARD3B
 par-3 family cell polarity regulator beta
 44
 0.99
chr2_133015015_133015166 0.28 ENSG00000221288
 .
 437
 0.85
chr10_112159035_112159217 0.28 ENSG00000221359
 .
 34873
 0.17
chr2_41837870_41838465 0.28 ENSG00000221372
 .
 14641
 0.29
chr11_74022029_74022645 0.28 P4HA3
 prolyl 4-hydroxylase, alpha polypeptide III
 348
 0.87
chr11_5618695_5618968 0.28 TRIM6
 tripartite motif containing 6
 795
 0.34
chr3_38150153_38150438 0.28 ENSG00000201965
 .
 16590
 0.14
chr12_53443889_53444561 0.28 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
 255
 0.86
chr1_30556615_30556878 0.28 ENSG00000222787
 .
 198997
 0.03
chr1_59229210_59229361 0.28 ENSG00000264081
 .
 1322
 0.47
chr19_16272076_16272227 0.28 CIB3
 calcium and integrin binding family member 3
 12135
 0.11
chr5_2752285_2752739 0.28 C5orf38
 chromosome 5 open reading frame 38
 133
 0.91
chr2_242499136_242499442 0.27 BOK-AS1
 BOK antisense RNA 1
 897
 0.38
chr4_100326128_100326285 0.27 ADH7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
 25242
 0.19
chr5_36608256_36608472 0.27 SLC1A3
 solute carrier family 1 (glial high affinity glutamate transporter), member 3
 67
 0.99
chr7_117468363_117468588 0.27 CTTNBP2
 cortactin binding protein 2
 36641
 0.22
chr4_23890798_23891066 0.27 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
 726
 0.8
chr13_77457508_77457742 0.27 KCTD12
 potassium channel tetramerization domain containing 12
 2900
 0.26
chr1_6795750_6796041 0.27 ENSG00000239166
 .
 16884
 0.16
chr17_41327724_41327928 0.27 NBR1
 neighbor of BRCA1 gene 1
 4566
 0.16
chr3_141378576_141378773 0.27 RNF7
 ring finger protein 7
 78372
 0.09
chr14_77606808_77607442 0.27 ZDHHC22
 zinc finger, DHHC-type containing 22
 38
 0.57
chr18_47090550_47090839 0.27 LIPG
 lipase, endothelial
 1979
 0.29
chr8_141129048_141129349 0.27 C8orf17
 chromosome 8 open reading frame 17
 185782
 0.03
chr15_44450903_44451054 0.27 FRMD5
 FERM domain containing 5
 35666
 0.19
chr9_93834219_93834510 0.27 SYK
 spleen tyrosine kinase
 244594
 0.02
chr1_17560057_17560274 0.27 PADI1
 peptidyl arginine deiminase, type I
 315
 0.88
chr3_185815817_185816010 0.27 ETV5
 ets variant 5
 10420
 0.22
chr8_118993051_118993436 0.27 EXT1
 exostosin glycosyltransferase 1
 129410
 0.06
chr1_144708044_144708206 0.27 RP11-640M9.2
92994
 0.07
chr9_36163620_36163822 0.27 CCIN
 calicin
 5668
 0.19
chr11_131618597_131618988 0.27 NTM
 neurotrimin
 87904
 0.1
chr17_42636239_42636390 0.27 FZD2
 frizzled family receptor 2
 1389
 0.42
chr8_35234925_35235076 0.27 UNC5D
 unc-5 homolog D (C. elegans)
 141707
 0.05
chr10_128947024_128947230 0.27 FAM196A
 family with sequence similarity 196, member A
 28146
 0.24
chr12_93293392_93293882 0.27 EEA1
 early endosome antigen 1
 29470
 0.2
chr10_24738095_24738342 0.27 KIAA1217
 KIAA1217
 144
 0.97
chr17_70636816_70636967 0.27 ENSG00000200783
 .
 23400
 0.24
chr12_105626746_105626963 0.27 APPL2
 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
 374
 0.89
chr22_43547615_43548743 0.27 TSPO
 translocator protein (18kDa)
 242
 0.9
chr11_73099035_73099239 0.27 RP11-809N8.2
8344
 0.15
chr2_219596210_219596511 0.27 TTLL4
 tubulin tyrosine ligase-like family, member 4
 5937
 0.15
chr4_24796744_24797030 0.26 SOD3
 superoxide dismutase 3, extracellular
 198
 0.97
chr19_55917680_55917831 0.26 UBE2S
 ubiquitin-conjugating enzyme E2S
 1332
 0.21
chr11_7013739_7013936 0.26 ZNF214
 zinc finger protein 214
 27629
 0.13
chr1_152488256_152488562 0.26 CRCT1
 cysteine-rich C-terminal 1
 1431
 0.33

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.4 GO:0031223 auditory behavior(GO:0031223)
0.1 0.5 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0007343 egg activation(GO:0007343)
0.1 0.2 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.1 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.3 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.1 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.3 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 0.3 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.1 0.3 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0060872 semicircular canal development(GO:0060872)
0.1 0.4 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101)
0.1 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.5 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.4 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.1 0.2 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.2 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.6 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.3 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.3 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.2 GO:0090026 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.8 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0042482 positive regulation of odontogenesis(GO:0042482)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.3 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.2 GO:0036473 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.3 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.2 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0032373 positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:0046398 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.7 GO:0016358 dendrite development(GO:0016358)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0045916 negative regulation of protein processing(GO:0010955) negative regulation of complement activation(GO:0045916) negative regulation of protein maturation(GO:1903318) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:0060008 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0 0.9 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.0 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0061515 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.4 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.0 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.2 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.0 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.1 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:0042754 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754) negative regulation of behavior(GO:0048521)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0099518 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0099504 synaptic vesicle cycle(GO:0099504)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0046851 negative regulation of bone remodeling(GO:0046851)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.1 GO:0071445 obsolete cellular response to protein stimulus(GO:0071445)
0.0 0.1 GO:0019430 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0035338 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.0 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0043584 nose development(GO:0043584)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.2 GO:0001940 male pronucleus(GO:0001940)
0.1 0.6 GO:0043205 fibril(GO:0043205)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.0 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 4.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0030016 myofibril(GO:0030016)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.7 GO:0030553 cGMP binding(GO:0030553)
0.1 0.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0005497 androgen binding(GO:0005497)
0.1 0.3 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0019798 procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.0 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC