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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZIC2_GLI1

Z-value: 0.70

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Transcription factors associated with ZIC2_GLI1

Gene Symbol Gene ID Gene Info
ZIC2
ENSG00000043355.6 ZIC2
GLI1
ENSG00000111087.5 GLI1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
GLI1chr12_57854051_578542021480.8945500.531.5e-01Click!
GLI1chr12_57853426_578537533290.7455220.472.0e-01Click!
GLI1chr12_57854714_578548655150.580095-0.402.9e-01Click!
GLI1chr12_57855715_5785618715240.1952590.343.7e-01Click!
GLI1chr12_57854208_57854360100.9431640.225.7e-01Click!
ZIC2chr13_100631982_10063213319690.3173360.684.3e-02Click!
ZIC2chr13_100638993_10063914450420.202545-0.581.1e-01Click!
ZIC2chr13_100632387_10063279214370.4053860.551.3e-01Click!
ZIC2chr13_100636352_10063650324010.2783660.501.7e-01Click!
ZIC2chr13_100633089_1006332918360.6100600.491.8e-01Click!

Activity of the ZIC2_GLI1 motif across conditions

Conditions sorted by the z-value of the ZIC2_GLI1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_29836748_29836938 0.68 MVP
 major vault protein
 4090
 0.07
chr14_101294075_101294314 0.45 AL117190.2
1343
 0.15
chr9_132935666_132935932 0.36 NCS1
 neuronal calcium sensor 1
 942
 0.6
chr9_97906510_97906877 0.31 ENSG00000251884
 .
 1870
 0.3
chr22_31502387_31502566 0.29 SELM
 Selenoprotein M
 1078
 0.36
chr10_5617288_5617517 0.27 CALML3-AS1
 CALML3 antisense RNA 1
 49193
 0.09
chr7_120970338_120970562 0.26 WNT16
 wingless-type MMTV integration site family, member 16
 1393
 0.55
chr11_27721206_27721474 0.26 BDNF
 brain-derived neurotrophic factor
 126
 0.97
chr1_214723918_214724069 0.26 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 573
 0.84
chr8_20121163_20121339 0.25 LZTS1
 leucine zipper, putative tumor suppressor 1
 8448
 0.2
chr17_18062032_18062240 0.23 MYO15A
 myosin XVA
 484
 0.71
chrX_12809123_12809409 0.23 PRPS2
 phosphoribosyl pyrophosphate synthetase 2
 208
 0.96
chr15_71504267_71504460 0.22 RP11-673C5.2
22982
 0.23
chr3_187870883_187871050 0.21 LPP
 LIM domain containing preferred translocation partner in lipoma
 106
 0.93
chr16_86613649_86613835 0.21 FOXL1
 forkhead box L1
 1627
 0.34
chr12_107297081_107297446 0.21 RP11-412D9.4
52012
 0.12
chr5_178956987_178957198 0.21 RUFY1
 RUN and FYVE domain containing 1
 20467
 0.17
chr19_13319766_13319917 0.21 CACNA1A
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 48373
 0.08
chr5_60602887_60603064 0.21 ZSWIM6
 zinc finger, SWIM-type containing 6
 25125
 0.25
chr6_170055214_170055550 0.20 WDR27
 WD repeat domain 27
 5406
 0.19
chr17_754296_754705 0.20 NXN
 nucleoredoxin
 12837
 0.15
chr3_147015992_147016163 0.19 RP11-649A16.1
72366
 0.11
chr6_35285702_35286007 0.19 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 8339
 0.18
chr1_45309015_45309207 0.19 PTCH2
 patched 2
 376
 0.75
chr1_214453711_214453918 0.19 SMYD2
 SET and MYND domain containing 2
 762
 0.77
chr2_69244184_69244393 0.19 ANTXR1
 anthrax toxin receptor 1
 3759
 0.26
chr4_72053226_72053895 0.18 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 516
 0.88
chr18_42030332_42030483 0.18 SETBP1
 SET binding protein 1
 229731
 0.02
chr11_34938171_34938707 0.18 PDHX
 pyruvate dehydrogenase complex, component X
 251
 0.64
chrX_49126619_49127035 0.18 PPP1R3F
 protein phosphatase 1, regulatory subunit 3F
 257
 0.83
chr4_187901794_187901964 0.18 ENSG00000252382
 .
 123269
 0.06
chr17_10100912_10101063 0.18 GAS7
 growth arrest-specific 7
 881
 0.65
chr8_142069585_142069736 0.18 PTK2
 protein tyrosine kinase 2
 57451
 0.11
chr5_150460766_150460936 0.18 TNIP1
 TNFAIP3 interacting protein 1
 146
 0.96
chr12_13197333_13197564 0.17 KIAA1467
 KIAA1467
 230
 0.92
chr14_102786393_102786880 0.17 ZNF839
 zinc finger protein 839
 540
 0.71
chrX_329574_329729 0.17 PPP2R3B
 protein phosphatase 2, regulatory subunit B'', beta
 5128
 0.27
chrY_279574_279727 0.17 NA
 NA
 > 106
 NA
chr2_32502966_32503192 0.17 YIPF4
 Yip1 domain family, member 4
 100
 0.97
chr15_68573802_68573977 0.17 FEM1B
 fem-1 homolog b (C. elegans)
 1592
 0.39
chr1_172110530_172111247 0.17 ENSG00000207949
 .
 2841
 0.22
chr5_146783513_146783669 0.16 CTB-108O6.2
2268
 0.31
chr11_95887560_95887798 0.16 ENSG00000266192
 .
 186923
 0.03
chr3_11314161_11314473 0.16 ATG7
 autophagy related 7
 208
 0.96
chr19_47163250_47163584 0.16 DACT3-AS1
 DACT3 antisense RNA 1
 204
 0.83
chr3_10028091_10028485 0.15 EMC3
 ER membrane protein complex subunit 3
 78
 0.92
chr17_27072661_27072812 0.15 TRAF4
 TNF receptor-associated factor 4
 1025
 0.2
chr3_10067619_10067972 0.15 FANCD2
 Fanconi anemia, complementation group D2
 303
 0.79
chr3_50378734_50378978 0.15 ZMYND10-AS1
 ZMYND10 antisense RNA 1
 319
 0.54
chr19_1017181_1017478 0.15 TMEM259
 transmembrane protein 259
 93
 0.91
chr13_111061542_111061693 0.15 ENSG00000238629
 .
 4935
 0.26
chr6_26016611_26016935 0.15 HIST1H1A
 histone cluster 1, H1a
 1267
 0.21
chr15_40697977_40698740 0.15 IVD
 isovaleryl-CoA dehydrogenase
 83
 0.94
chrX_47930156_47930426 0.15 ZNF630
 zinc finger protein 630
 192
 0.92
chr10_12111309_12111515 0.14 DHTKD1
 dehydrogenase E1 and transketolase domain containing 1
 389
 0.84
chr16_8891744_8892217 0.14 PMM2
 phosphomannomutase 2
 256
 0.68
chr7_4680990_4681313 0.14 FOXK1
 forkhead box K1
 2237
 0.38
chr1_3285886_3286037 0.14 PRDM16
 PR domain containing 16
 27094
 0.21
chr5_98109376_98109557 0.14 RGMB
 repulsive guidance molecule family member b
 127
 0.72
chr5_97550577_97550728 0.14 ENSG00000223053
 .
 424283
 0.01
chr17_34115736_34115943 0.14 MMP28
 matrix metallopeptidase 28
 6872
 0.1
chr15_38117163_38117383 0.14 TMCO5A
 transmembrane and coiled-coil domains 5A
 96867
 0.09
chr5_179248266_179248778 0.13 SQSTM1
 sequestosome 1
 601
 0.58
chr1_67142291_67142442 0.13 AL139147.1
 Uncharacterized protein
 344
 0.88
chr10_51622913_51623296 0.13 TIMM23
 translocase of inner mitochondrial membrane 23 homolog (yeast)
 99
 0.97
chr15_90357053_90357234 0.13 ANPEP
 alanyl (membrane) aminopeptidase
 951
 0.46
chrX_134166936_134167548 0.13 FAM127A
 family with sequence similarity 127, member A
 909
 0.53
chr1_20834735_20834945 0.13 MUL1
 mitochondrial E3 ubiquitin protein ligase 1
 186
 0.95
chr17_38225914_38226065 0.13 THRA
 thyroid hormone receptor, alpha
 833
 0.48
chr22_37699623_37699774 0.13 CYTH4
 cytohesin 4
 6311
 0.18
chr7_38350810_38351032 0.13 STARD3NL
 STARD3 N-terminal like
 132924
 0.05
chr7_101579659_101580126 0.13 CTB-181H17.1
23504
 0.22
chr20_45887719_45887887 0.13 ZMYND8
 zinc finger, MYND-type containing 8
 39841
 0.12
chr8_102121369_102121647 0.13 ENSG00000202360
 .
 28679
 0.21
chr14_24584036_24584230 0.13 DCAF11
 DDB1 and CUL4 associated factor 11
 63
 0.51
chr2_189748856_189749076 0.13 AC079613.1
44795
 0.16
chr10_51371455_51372104 0.12 TIMM23B
 translocase of inner mitochondrial membrane 23 homolog B (yeast)
 343
 0.58
chr17_63096937_63097327 0.12 RGS9
 regulator of G-protein signaling 9
 36434
 0.15
chr10_75547124_75547275 0.12 ZSWIM8
 zinc finger, SWIM-type containing 8
 1779
 0.16
chr8_96146036_96146378 0.12 PLEKHF2
 pleckstrin homology domain containing, family F (with FYVE domain) member 2
 97
 0.97
chr1_55681610_55681784 0.12 USP24
 ubiquitin specific peptidase 24
 911
 0.63
chr7_130131272_130131861 0.12 MEST
 mesoderm specific transcript
 368
 0.77
chr19_44036829_44037014 0.12 ZNF575
 zinc finger protein 575
 195
 0.88
chr22_42679165_42679458 0.12 TCF20
 transcription factor 20 (AR1)
 60311
 0.1
chr16_66440546_66441157 0.12 CDH5
 cadherin 5, type 2 (vascular endothelium)
 11493
 0.17
chr1_201425782_201426096 0.12 PHLDA3
 pleckstrin homology-like domain, family A, member 3
 12373
 0.15
chr9_20340314_20340473 0.12 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
 42074
 0.15
chr5_158326789_158326940 0.12 CTD-2363C16.1
83150
 0.1
chr9_98278987_98279233 0.12 PTCH1
 patched 1
 137
 0.95
chr4_110354244_110354664 0.11 SEC24B-AS1
 SEC24B antisense RNA 1
 466
 0.46
chr4_1863859_1864305 0.11 LETM1
 leucine zipper-EF-hand containing transmembrane protein 1
 6108
 0.16
chr10_81002854_81003026 0.11 ZMIZ1
 zinc finger, MIZ-type containing 1
 63035
 0.13
chr20_36149696_36149913 0.11 NNAT
 neuronatin
 183
 0.64
chr2_114648081_114648567 0.11 ACTR3
 ARP3 actin-related protein 3 homolog (yeast)
 149
 0.97
chr19_16435025_16435277 0.11 CTD-2562J15.6
174
 0.78
chr20_5485005_5485184 0.11 RP5-1022P6.5
29180
 0.21
chr11_65682969_65683236 0.11 C11orf68
 chromosome 11 open reading frame 68
 2729
 0.12
chr20_62257766_62257982 0.11 GMEB2
 glucocorticoid modulatory element binding protein 2
 520
 0.48
chr17_39969662_39969906 0.10 FKBP10
 FK506 binding protein 10, 65 kDa
 601
 0.45
chr11_89867468_89867846 0.10 NAALAD2
 N-acetylated alpha-linked acidic dipeptidase 2
 40
 0.98
chr8_144922083_144922496 0.10 NRBP2
 nuclear receptor binding protein 2
 513
 0.61
chr17_61850012_61850913 0.10 CCDC47
 coiled-coil domain containing 47
 468
 0.45
chr7_26903418_26904290 0.10 SKAP2
 src kinase associated phosphoprotein 2
 508
 0.86
chr1_173794371_173794522 0.10 DARS2
 aspartyl-tRNA synthetase 2, mitochondrial
 649
 0.46
chr12_32260246_32261058 0.10 RP11-843B15.2
190
 0.75
chr17_77966356_77966507 0.10 CTD-2529O21.1
209
 0.88
chr19_927045_927244 0.10 ARID3A
 AT rich interactive domain 3A (BRIGHT-like)
 1144
 0.25
chr1_154531550_154531753 0.10 UBE2Q1
 ubiquitin-conjugating enzyme E2Q family member 1
 542
 0.64
chr2_26987219_26988126 0.10 SLC35F6
 solute carrier family 35, member F6
 515
 0.78
chr4_183481639_183481857 0.10 ENSG00000252343
 .
 11936
 0.26
chr3_120149251_120149402 0.10 FSTL1
 follistatin-like 1
 20512
 0.22
chr16_82431120_82431271 0.10 ENSG00000264502
 .
 50011
 0.15
chr12_26986439_26986924 0.10 ITPR2
 inositol 1,4,5-trisphosphate receptor, type 2
 550
 0.83
chr6_24910461_24910676 0.10 FAM65B
 family with sequence similarity 65, member B
 627
 0.77
chr14_72053260_72053532 0.10 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 398
 0.92
chr3_127872049_127872245 0.10 EEFSEC
 eukaryotic elongation factor, selenocysteine-tRNA-specific
 150
 0.86
chrX_47518304_47518499 0.09 UXT
 ubiquitously-expressed, prefoldin-like chaperone
 115
 0.54
chr10_116020157_116020308 0.09 VWA2
 von Willebrand factor A domain containing 2
 21143
 0.21
chr4_56212171_56212371 0.09 SRD5A3
 steroid 5 alpha-reductase 3
 5
 0.98
chr16_27325280_27325496 0.09 IL4R
 interleukin 4 receptor
 75
 0.97
chr8_17555063_17555276 0.09 MTUS1
 microtubule associated tumor suppressor 1
 10
 0.97
chr12_132688811_132688962 0.09 GALNT9
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
 1451
 0.44
chr3_112358415_112358703 0.09 CCDC80
 coiled-coil domain containing 80
 1557
 0.48
chr16_75328031_75328182 0.09 ENSG00000252101
 .
 7410
 0.15
chr3_49592272_49592564 0.09 BSN
 bassoon presynaptic cytomatrix protein
 496
 0.78
chr7_77326845_77327188 0.09 RSBN1L
 round spermatid basic protein 1-like
 548
 0.83
chr3_142956189_142956340 0.09 ENSG00000211483
 .
 71774
 0.1
chr22_46473276_46473626 0.09 FLJ27365
 hsa-mir-4763
 2741
 0.14
chr20_62257208_62257699 0.09 GMEB2
 glucocorticoid modulatory element binding protein 2
 941
 0.32
chr15_90356636_90356804 0.09 ANPEP
 alanyl (membrane) aminopeptidase
 1374
 0.33
chr1_23079970_23080247 0.09 ENSG00000216157
 .
 4704
 0.19
chr2_46774565_46774716 0.09 RHOQ
 ras homolog family member Q
 4101
 0.17
chr6_85248911_85249062 0.09 RP11-132M7.3
150157
 0.05
chr13_114823633_114823784 0.09 RASA3
 RAS p21 protein activator 3
 19730
 0.23
chr16_85795783_85795934 0.09 C16orf74
 chromosome 16 open reading frame 74
 11123
 0.1
chr15_78171702_78171998 0.09 CSPG4P13
 chondroitin sulfate proteoglycan 4 pseudogene 13
 15176
 0.15
chr9_130854743_130854894 0.09 SLC25A25
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
 1075
 0.29
chr3_72640881_72641032 0.09 ENSG00000199469
 .
 15114
 0.22
chr8_47829477_47829948 0.09 ENSG00000252594
 .
 87040
 0.1
chr19_980574_980725 0.09 WDR18
 WD repeat domain 18
 3682
 0.1
chr1_55352544_55352822 0.09 RP11-67L3.5
135
 0.55
chr1_72749537_72750410 0.09 NEGR1
 neuronal growth regulator 1
 1556
 0.58
chr11_46300240_46300518 0.09 CREB3L1
 cAMP responsive element binding protein 3-like 1
 1151
 0.46
chr3_71804156_71804307 0.09 EIF4E3
 eukaryotic translation initiation factor 4E family member 3
 307
 0.82
chr11_129764495_129764646 0.09 NFRKB
 nuclear factor related to kappaB binding protein
 234
 0.95
chr9_117149358_117150269 0.08 AKNA
 AT-hook transcription factor
 430
 0.85
chr7_130791022_130791700 0.08 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 428
 0.85
chr8_32406806_32407051 0.08 NRG1
 neuregulin 1
 683
 0.82
chr16_18494169_18494622 0.08 PKD1P5
 polycystic kidney disease 1 (autosomal dominant) pseudogene 5
 1402
 0.22
chr9_97818540_97818804 0.08 ENSG00000207563
 .
 28818
 0.12
chr8_38964877_38965090 0.08 ADAM32
 ADAM metallopeptidase domain 32
 65
 0.98
chr8_22102673_22103420 0.08 POLR3D
 polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
 298
 0.63
chr15_95847267_95847418 0.08 ENSG00000222076
 .
 441691
 0.01
chr7_20370368_20370519 0.08 ITGB8
 integrin, beta 8
 118
 0.93
chr7_65670330_65671074 0.08 TPST1
 tyrosylprotein sulfotransferase 1
 398
 0.87
chr16_56672198_56672419 0.08 MT1A
 metallothionein 1A
 270
 0.75
chr3_49449862_49450835 0.08 TCTA
 T-cell leukemia translocation altered
 709
 0.34
chr1_6674083_6674241 0.08 PHF13
 PHD finger protein 13
 417
 0.47
chr8_37246004_37246155 0.08 RP11-150O12.6
128460
 0.05
chr2_189844043_189844303 0.08 ENSG00000221502
 .
 1355
 0.48
chr7_155436479_155436836 0.08 AC009403.2
 Protein LOC100506302
 438
 0.51
chr5_158878566_158878856 0.08 ENSG00000266432
 .
 74235
 0.11
chr1_206879659_206879853 0.08 MAPKAPK2
 mitogen-activated protein kinase-activated protein kinase 2
 21374
 0.13
chr20_35171113_35171392 0.08 MYL9
 myosin, light chain 9, regulatory
 1352
 0.35
chr2_20271939_20272144 0.08 RP11-644K8.1
20146
 0.16
chr7_134472278_134472429 0.08 CALD1
 caldesmon 1
 7924
 0.3
chr11_111411757_111412020 0.08 LAYN
 layilin
 170
 0.92
chr13_108022701_108022852 0.07 ENSG00000201847
 .
 49465
 0.19
chr3_64430283_64430501 0.07 PRICKLE2
 prickle homolog 2 (Drosophila)
 666
 0.79
chr17_55055562_55056181 0.07 SCPEP1
 serine carboxypeptidase 1
 376
 0.79
chr2_9983595_9984276 0.07 TAF1B
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
 283
 0.93
chr17_43205760_43205911 0.07 PLCD3
 phospholipase C, delta 3
 4056
 0.12
chr17_6346848_6347134 0.07 FAM64A
 family with sequence similarity 64, member A
 744
 0.65
chr11_35676290_35676441 0.07 TRIM44
 tripartite motif containing 44
 7988
 0.24
chr3_147109765_147110149 0.07 ZIC1
 Zic family member 1
 1725
 0.33
chr20_42143535_42143824 0.07 L3MBTL1
 l(3)mbt-like 1 (Drosophila)
 513
 0.75
chr12_53441858_53442099 0.07 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
 755
 0.42
chr12_121974248_121974441 0.07 KDM2B
 lysine (K)-specific demethylase 2B
 204
 0.95
chr8_67525864_67526623 0.07 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 714
 0.66
chr1_153584868_153585142 0.07 S100A16
 S100 calcium binding protein A16
 554
 0.53
chr9_123476196_123476418 0.07 MEGF9
 multiple EGF-like-domains 9
 305
 0.93
chr9_124131284_124131757 0.07 STOM
 stomatin
 963
 0.5
chr5_325316_325467 0.07 AHRR
 aryl-hydrocarbon receptor repressor
 2636
 0.26
chr11_69460305_69460629 0.07 CCND1
 cyclin D1
 4493
 0.24
chr20_18477327_18477868 0.07 RBBP9
 retinoblastoma binding protein 9
 290
 0.85
chr4_8595158_8595423 0.07 CPZ
 carboxypeptidase Z
 807
 0.68
chr10_52751128_52751393 0.07 PRKG1
 protein kinase, cGMP-dependent, type I
 142
 0.97
chr17_75318499_75318729 0.07 SEPT9
 septin 9
 78
 0.98
chr10_86056124_86056314 0.07 CCSER2
 coiled-coil serine-rich protein 2
 32123
 0.16
chr20_56884148_56884425 0.07 PPP4R1L
 protein phosphatase 4, regulatory subunit 1-like
 209
 0.75
chr10_180203_180821 0.07 ZMYND11
 zinc finger, MYND-type containing 11
 88
 0.98
chr2_24270267_24270418 0.07 C2orf44
 chromosome 2 open reading frame 44
 111
 0.92
chr19_47735595_47736220 0.07 BBC3
 BCL2 binding component 3
 116
 0.95
chr9_91661673_91661920 0.07 SHC3
 SHC (Src homology 2 domain containing) transforming protein 3
 4744
 0.25
chr16_83987560_83987743 0.07 OSGIN1
 oxidative stress induced growth inhibitor 1
 807
 0.57
chr6_21886939_21887090 0.07 ENSG00000222515
 .
 198759
 0.03
chr19_5292236_5292538 0.07 PTPRS
 protein tyrosine phosphatase, receptor type, S
 411
 0.89
chr9_91429388_91429539 0.07 ENSG00000265873
 .
 68643
 0.13
chr17_4710527_4711001 0.07 PLD2
 phospholipase D2
 93
 0.93
chr6_155635765_155636118 0.06 TFB1M
 transcription factor B1, mitochondrial
 323
 0.92

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ZIC2_GLI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0060073 micturition(GO:0060073)
0.0 0.0 GO:0009111 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.0 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis