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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZKSCAN1

Z-value: 1.36

Motif logo

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Transcription factors associated with ZKSCAN1

Gene Symbol Gene ID Gene Info
ZKSCAN1
ENSG00000106261.12 zinc finger with KRAB and SCAN domains 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_99595694_99595948ZKSCAN1173830.0831850.693.8e-02Click!
chr7_99604623_99604774ZKSCAN185060.0942080.589.9e-02Click!
chr7_99613078_99613341ZKSCAN150.9521240.501.7e-01Click!
chr7_99615127_99615278ZKSCAN17570.457665-0.432.5e-01Click!
chr7_99620497_99620648ZKSCAN161270.097071-0.412.7e-01Click!

Activity of the ZKSCAN1 motif across conditions

Conditions sorted by the z-value of the ZKSCAN1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_48770476_48770817 1.21 TMEM189
 transmembrane protein 189
 311
 0.62
chr9_123687593_123687825 1.18 TRAF1
 TNF receptor-associated factor 1
 3338
 0.27
chr22_44577668_44577918 1.06 PARVG
 parvin, gamma
 52
 0.99
chr19_10342329_10342480 1.01 DNMT1
 DNA (cytosine-5-)-methyltransferase 1
 442
 0.39
chr6_42015554_42016199 1.00 CCND3
 cyclin D3
 548
 0.7
chr19_16254302_16254453 0.99 HSH2D
 hematopoietic SH2 domain containing
 118
 0.94
chr6_159465090_159465296 0.98 TAGAP
 T-cell activation RhoGTPase activating protein
 857
 0.62
chr11_46367119_46367443 0.96 DGKZ
 diacylglycerol kinase, zeta
 294
 0.88
chr8_98806681_98806832 0.96 LAPTM4B
 lysosomal protein transmembrane 4 beta
 18679
 0.16
chr7_949432_949583 0.95 ADAP1
 ArfGAP with dual PH domains 1
 4793
 0.16
chr1_198611578_198611729 0.93 PTPRC
 protein tyrosine phosphatase, receptor type, C
 3361
 0.31
chr20_47436352_47436503 0.90 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 7993
 0.28
chr5_131762557_131762944 0.81 AC116366.5
344
 0.83
chr11_128343021_128343263 0.76 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 32147
 0.21
chr2_240219542_240220118 0.75 ENSG00000265215
 .
 7327
 0.19
chr6_36922069_36922220 0.72 PI16
 peptidase inhibitor 16
 65
 0.97
chr20_31125041_31125259 0.72 C20orf112
 chromosome 20 open reading frame 112
 950
 0.54
chr19_13215215_13215439 0.71 LYL1
 lymphoblastic leukemia derived sequence 1
 1352
 0.27
chr3_111851637_111852199 0.71 GCSAM
 germinal center-associated, signaling and motility
 154
 0.73
chr11_67184219_67184479 0.70 CARNS1
 carnosine synthase 1
 792
 0.34
chr15_75493595_75493850 0.70 C15orf39
 chromosome 15 open reading frame 39
 496
 0.7
chr1_208046696_208046851 0.70 CD34
 CD34 molecule
 17064
 0.25
chr19_3178230_3178381 0.69 S1PR4
 sphingosine-1-phosphate receptor 4
 431
 0.74
chr19_10831379_10831550 0.66 DNM2
 dynamin 2
 2227
 0.18
chr1_17682926_17683077 0.64 AC004824.2
 Uncharacterized protein
 6931
 0.18
chr13_99911056_99911338 0.64 GPR18
 G protein-coupled receptor 18
 515
 0.8
chr12_125424789_125424964 0.64 UBC
 ubiquitin C
 22962
 0.14
chr2_10444029_10444225 0.63 HPCAL1
 hippocalcin-like 1
 301
 0.89
chr5_71604472_71604655 0.61 ENSG00000244748
 .
 5952
 0.2
chr6_165723730_165723881 0.61 C6orf118
 chromosome 6 open reading frame 118
 709
 0.81
chr19_18113119_18113338 0.61 ARRDC2
 arrestin domain containing 2
 1287
 0.37
chr17_36858727_36858878 0.60 ENSG00000265930
 .
 218
 0.82
chr19_35632381_35632614 0.58 FXYD1
 FXYD domain containing ion transport regulator 1
 1488
 0.2
chr6_52929771_52930181 0.56 FBXO9
 F-box protein 9
 180
 0.92
chr12_50902852_50903181 0.56 DIP2B
 DIP2 disco-interacting protein 2 homolog B (Drosophila)
 4126
 0.27
chr15_41850352_41850568 0.55 TYRO3
 TYRO3 protein tyrosine kinase
 587
 0.7
chr5_134240090_134240263 0.55 PCBD2
 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
 420
 0.81
chr7_30766706_30766866 0.55 INMT
 indolethylamine N-methyltransferase
 24965
 0.16
chr19_2489456_2489664 0.54 GADD45B
 growth arrest and DNA-damage-inducible, beta
 13206
 0.14
chr2_144005287_144005438 0.54 RP11-190J23.1
75621
 0.11
chr15_45002906_45003073 0.54 B2M
 beta-2-microglobulin
 686
 0.62
chr11_79212076_79212227 0.54 TENM4
 teneurin transmembrane protein 4
 60456
 0.14
chrX_23970840_23971181 0.53 CXorf58
 chromosome X open reading frame 58
 42510
 0.13
chr9_126101480_126101665 0.53 CRB2
 crumbs homolog 2 (Drosophila)
 16877
 0.22
chr1_173445561_173445725 0.53 PRDX6
 peroxiredoxin 6
 762
 0.68
chr15_40731920_40732071 0.52 BAHD1
 bromo adjacent homology domain containing 1
 75
 0.94
chr1_28199781_28200360 0.52 THEMIS2
 thymocyte selection associated family member 2
 991
 0.4
chr13_52411655_52411806 0.50 CCDC70
 coiled-coil domain containing 70
 24387
 0.17
chr19_15574852_15575181 0.50 RASAL3
 RAS protein activator like 3
 366
 0.8
chr9_132647660_132648047 0.49 FNBP1
 formin binding protein 1
 33736
 0.12
chr17_40439619_40439799 0.49 STAT5A
 signal transducer and activator of transcription 5A
 144
 0.93
chr8_37755503_37755707 0.49 RAB11FIP1
 RAB11 family interacting protein 1 (class I)
 1367
 0.34
chr4_1210592_1210772 0.48 CTBP1
 C-terminal binding protein 1
 2432
 0.21
chr12_31811913_31812109 0.48 METTL20
 methyltransferase like 20
 110
 0.96
chr3_161261196_161261347 0.47 OTOL1
 otolin 1
 46675
 0.2
chr16_67062127_67062421 0.46 CBFB
 core-binding factor, beta subunit
 745
 0.53
chr16_27326766_27327107 0.46 IL4R
 interleukin 4 receptor
 1623
 0.4
chr19_6801178_6801329 0.46 VAV1
 vav 1 guanine nucleotide exchange factor
 17124
 0.13
chr14_95963717_95963868 0.45 RP11-1070N10.3
 Uncharacterized protein
 18681
 0.14
chr9_115096689_115097200 0.45 PTBP3
 polypyrimidine tract binding protein 3
 997
 0.57
chr1_6659044_6659355 0.45 KLHL21
 kelch-like family member 21
 677
 0.56
chr15_60771714_60772006 0.45 RP11-219B17.1
441
 0.52
chr4_109087263_109087414 0.45 LEF1
 lymphoid enhancer-binding factor 1
 119
 0.95
chr4_2814595_2815029 0.44 SH3BP2
 SH3-domain binding protein 2
 781
 0.66
chr10_23384240_23384391 0.44 MSRB2
 methionine sulfoxide reductase B2
 120
 0.97
chr10_103539043_103539292 0.44 FGF8
 fibroblast growth factor 8 (androgen-induced)
 3340
 0.19
chr7_86689559_86689710 0.44 KIAA1324L
 KIAA1324-like
 619
 0.81
chr19_2489761_2489912 0.43 ENSG00000252962
 .
 13303
 0.14
chr17_73151022_73151194 0.43 HN1
 hematological and neurological expressed 1
 330
 0.75
chr15_77286829_77286980 0.42 PSTPIP1
 proline-serine-threonine phosphatase interacting protein 1
 522
 0.79
chr20_62198919_62199070 0.42 HELZ2
 helicase with zinc finger 2, transcriptional coactivator
 433
 0.7
chr6_79902044_79902327 0.41 HMGN3-AS1
 HMGN3 antisense RNA 1
 41250
 0.16
chr19_45258275_45258481 0.41 BCL3
 B-cell CLL/lymphoma 3
 3800
 0.13
chr22_24180306_24180495 0.41 DERL3
 derlin 3
 791
 0.44
chr19_8070956_8071107 0.41 ELAVL1
 ELAV like RNA binding protein 1
 488
 0.72
chr15_81593596_81593907 0.41 IL16
 interleukin 16
 1994
 0.33
chr19_42388528_42389094 0.41 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 296
 0.84
chr2_74611000_74611151 0.41 DCTN1
 dynactin 1
 1493
 0.21
chr9_131964929_131965166 0.41 RP11-247A12.2
1453
 0.33
chr1_55678186_55678720 0.41 USP24
 ubiquitin specific peptidase 24
 2309
 0.34
chr1_85871559_85871710 0.40 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 1454
 0.45
chr12_71167942_71168093 0.39 PTPRR
 protein tyrosine phosphatase, receptor type, R
 14745
 0.28
chr1_27849169_27849399 0.39 RP1-159A19.4
3032
 0.23
chr1_234613311_234613591 0.39 TARBP1
 TAR (HIV-1) RNA binding protein 1
 1398
 0.49
chr20_43279687_43280217 0.38 ADA
 adenosine deaminase
 380
 0.81
chr20_3998751_3998989 0.38 RNF24
 ring finger protein 24
 2641
 0.31
chr8_134511768_134511919 0.38 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 217
 0.97
chr13_36410557_36410708 0.37 DCLK1
 doublecortin-like kinase 1
 19147
 0.29
chrY_15590512_15590663 0.37 UTY
 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
 958
 0.72
chr11_75063727_75063930 0.37 ARRB1
 arrestin, beta 1
 955
 0.48
chr6_157098499_157098696 0.37 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 466
 0.78
chr9_137856018_137856169 0.37 FCN1
 ficolin (collagen/fibrinogen domain containing) 1
 46284
 0.11
chr6_10529373_10529624 0.36 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
 909
 0.59
chr7_155556612_155556872 0.36 RBM33
 RNA binding motif protein 33
 2508
 0.35
chr7_124289801_124290098 0.36 ENSG00000207214
 .
 2176
 0.46
chr22_45680566_45680776 0.35 UPK3A
 uroplakin 3A
 192
 0.94
chrX_131622234_131622385 0.35 MBNL3
 muscleblind-like splicing regulator 3
 734
 0.78
chr7_100202948_100203247 0.35 PCOLCE-AS1
 PCOLCE antisense RNA 1
 1268
 0.23
chr9_139444261_139444412 0.35 RP11-611D20.2
754
 0.45
chr16_19729638_19729939 0.35 IQCK
 IQ motif containing K
 151
 0.61
chr2_75065127_75065278 0.35 HK2
 hexokinase 2
 2905
 0.34
chr13_41372571_41372761 0.34 SLC25A15
 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
 5372
 0.18
chr19_35820197_35820463 0.34 CD22
 CD22 molecule
 215
 0.83
chr19_45606414_45606793 0.33 PPP1R37
 protein phosphatase 1, regulatory subunit 37
 10171
 0.09
chr5_118609514_118610204 0.33 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 5410
 0.21
chr1_42206292_42206443 0.33 ENSG00000264896
 .
 18445
 0.24
chr1_87169604_87170085 0.33 RP4-612B15.3
301
 0.59
chr17_76772724_76772875 0.33 CYTH1
 cytohesin 1
 5555
 0.2
chr17_36858943_36859359 0.33 ENSG00000265930
 .
 567
 0.49
chr2_71751488_71751639 0.32 DYSF
 dysferlin
 57731
 0.15
chr5_134735051_134735464 0.32 H2AFY
 H2A histone family, member Y
 55
 0.79
chr11_76091032_76091428 0.31 PRKRIR
 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
 756
 0.46
chr8_66751055_66751459 0.31 PDE7A
 phosphodiesterase 7A
 274
 0.95
chr19_2092800_2093080 0.31 MOB3A
 MOB kinase activator 3A
 2765
 0.15
chr10_106089117_106089268 0.31 ITPRIP
 inositol 1,4,5-trisphosphate receptor interacting protein
 510
 0.71
chr11_75943170_75943321 0.31 WNT11
 wingless-type MMTV integration site family, member 11
 21465
 0.18
chrX_78402769_78403059 0.31 GPR174
 G protein-coupled receptor 174
 23555
 0.28
chr5_169724277_169724686 0.31 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 750
 0.71
chr12_46063121_46063382 0.31 ARID2
 AT rich interactive domain 2 (ARID, RFX-like)
 60197
 0.15
chr3_69590054_69590354 0.30 FRMD4B
 FERM domain containing 4B
 287
 0.95
chr16_79123602_79124194 0.30 RP11-556H2.3
49
 0.98
chr15_78327297_78327492 0.30 ENSG00000221476
 .
 3479
 0.18
chr16_69346193_69346377 0.30 VPS4A
 vacuolar protein sorting 4 homolog A (S. cerevisiae)
 1026
 0.35
chr7_142498684_142498938 0.30 PRSS3P2
 protease, serine, 3 pseudogene 2
 17680
 0.17
chr7_149411220_149411666 0.30 KRBA1
 KRAB-A domain containing 1
 429
 0.87
chr1_11332767_11332951 0.29 UBIAD1
 UbiA prenyltransferase domain containing 1
 404
 0.83
chr12_120548897_120549070 0.29 RAB35
 RAB35, member RAS oncogene family
 5557
 0.17
chr3_148803795_148804035 0.29 HLTF-AS1
 HLTF antisense RNA 1
 204
 0.68
chr22_33040047_33040198 0.29 ENSG00000251890
 .
 8938
 0.25
chrX_109245290_109245568 0.29 TMEM164
 transmembrane protein 164
 434
 0.88
chr19_35494097_35494396 0.29 GRAMD1A
 GRAM domain containing 1A
 2886
 0.14
chr5_72731379_72731530 0.28 FOXD1
 forkhead box D1
 12898
 0.21
chrX_135578358_135578906 0.28 HTATSF1
 HIV-1 Tat specific factor 1
 606
 0.66
chr19_39420489_39421004 0.28 SARS2
 seryl-tRNA synthetase 2, mitochondrial
 27
 0.86
chr6_31240086_31240407 0.28 HLA-C
 major histocompatibility complex, class I, C
 383
 0.81
chr2_208007462_208007613 0.28 KLF7
 Kruppel-like factor 7 (ubiquitous)
 8676
 0.2
chr7_5571391_5571891 0.28 ACTB
 actin, beta
 1301
 0.32
chr8_142413039_142413204 0.28 CTD-3064M3.4
10447
 0.12
chr11_65379543_65379824 0.28 MAP3K11
 mitogen-activated protein kinase kinase kinase 11
 911
 0.31
chr1_230406303_230406454 0.28 RP5-956O18.2
2149
 0.36
chr17_43505837_43505988 0.28 ARHGAP27
 Rho GTPase activating protein 27
 1733
 0.23
chr17_33446349_33446789 0.28 RAD51D
 RAD51 paralog D
 4
 0.88
chr14_99727366_99727576 0.27 AL109767.1
1814
 0.39
chrX_47441424_47441613 0.27 TIMP1
 TIMP metallopeptidase inhibitor 1
 194
 0.91
chr11_67981482_67982050 0.26 SUV420H1
 suppressor of variegation 4-20 homolog 1 (Drosophila)
 471
 0.83
chr13_53484556_53484707 0.26 PCDH8
 protocadherin 8
 61856
 0.13
chr1_19812521_19812692 0.26 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 540
 0.74
chr5_170818755_170818906 0.26 NPM1
 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
 3945
 0.18
chr6_24925347_24925503 0.26 FAM65B
 family with sequence similarity 65, member B
 10763
 0.23
chrX_139006308_139006459 0.25 ENSG00000207633
 .
 7
 0.97
chr19_42376193_42376392 0.25 CD79A
 CD79a molecule, immunoglobulin-associated alpha
 4898
 0.12
chr15_65822500_65822707 0.25 PTPLAD1
 protein tyrosine phosphatase-like A domain containing 1
 153
 0.94
chr16_791373_791524 0.25 NARFL
 nuclear prelamin A recognition factor-like
 119
 0.88
chr19_4060134_4060285 0.25 CTD-2622I13.3
2538
 0.17
chr12_75875877_75876340 0.25 GLIPR1
 GLI pathogenesis-related 1
 1124
 0.49
chr1_111764570_111764791 0.25 CHI3L2
 chitinase 3-like 2
 4958
 0.15
chr15_75417454_75417605 0.24 ENSG00000252722
 .
 3522
 0.21
chr9_131842660_131843064 0.24 DOLPP1
 dolichyldiphosphatase 1
 517
 0.67
chr20_43513806_43514102 0.24 YWHAB
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
 363
 0.83
chr4_6942044_6942219 0.24 ENSG00000265953
 .
 12885
 0.15
chr5_173202456_173202607 0.24 ENSG00000263401
 .
 45450
 0.18
chr4_56814750_56814930 0.24 CEP135
 centrosomal protein 135kDa
 197
 0.95
chrX_152864941_152865619 0.24 FAM58A
 family with sequence similarity 58, member A
 220
 0.71
chrX_39796396_39796688 0.24 ENSG00000263972
 .
 99727
 0.08
chr20_826611_826818 0.23 FAM110A
 family with sequence similarity 110, member A
 947
 0.64
chr6_109560429_109560580 0.23 ENSG00000238474
 .
 52057
 0.12
chr14_105635560_105635849 0.23 JAG2
 jagged 2
 543
 0.75
chr11_48018118_48018269 0.23 PTPRJ
 protein tyrosine phosphatase, receptor type, J
 15914
 0.19
chr7_143072173_143072546 0.23 AC093673.5
5229
 0.12
chr8_1430917_1431068 0.23 DLGAP2
 discs, large (Drosophila) homolog-associated protein 2
 18540
 0.28
chr15_55569874_55570045 0.23 RAB27A
 RAB27A, member RAS oncogene family
 6852
 0.2
chr17_55332585_55332736 0.23 MSI2
 musashi RNA-binding protein 2
 552
 0.84
chr6_154570744_154570920 0.23 IPCEF1
 interaction protein for cytohesin exchange factors 1
 2016
 0.49
chr1_205409872_205410317 0.23 ENSG00000199059
 .
 7432
 0.17
chr19_5294712_5294863 0.23 PTPRS
 protein tyrosine phosphatase, receptor type, S
 1524
 0.49
chr3_97438061_97438212 0.23 RP11-389G6.3
40231
 0.17
chr10_124713000_124713296 0.22 C10orf88
 chromosome 10 open reading frame 88
 771
 0.61
chr1_26561482_26561883 0.22 CEP85
 centrosomal protein 85kDa
 989
 0.41
chr16_25269686_25269905 0.22 ZKSCAN2
 zinc finger with KRAB and SCAN domains 2
 543
 0.78
chr9_82317273_82317424 0.22 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 2350
 0.47
chr1_205256784_205256935 0.22 TMCC2
 transmembrane and coiled-coil domain family 2
 31530
 0.13
chr16_31520088_31520277 0.22 RP11-452L6.7
390
 0.47
chr15_70773947_70774098 0.22 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 220598
 0.02
chr12_4380598_4381153 0.22 CCND2
 cyclin D2
 2063
 0.27
chr22_38055772_38055923 0.22 PDXP
 pyridoxal (pyridoxine, vitamin B6) phosphatase
 1113
 0.27
chr7_157361164_157361701 0.22 ENSG00000207960
 .
 5682
 0.22
chr14_32671845_32671996 0.22 ENSG00000202337
 .
 555
 0.52
chr22_25003998_25004507 0.22 GGT1
 gamma-glutamyltransferase 1
 621
 0.67
chr8_131029198_131029390 0.22 FAM49B
 family with sequence similarity 49, member B
 81
 0.97
chr12_120966627_120966937 0.22 COQ5
 coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
 161
 0.91
chr1_201476350_201476659 0.21 CSRP1
 cysteine and glycine-rich protein 1
 117
 0.52
chr12_125034711_125034862 0.21 NCOR2
 nuclear receptor corepressor 2
 14637
 0.29
chr1_16302650_16302808 0.21 ZBTB17
 zinc finger and BTB domain containing 17
 102
 0.95
chr22_38082633_38082863 0.21 NOL12
 nucleolar protein 12
 418
 0.71
chr11_17497808_17497959 0.21 ABCC8
 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
 509
 0.81
chr4_40241072_40241223 0.21 RHOH
 ras homolog family member H
 39183
 0.16
chr1_38312116_38312382 0.21 MTF1
 metal-regulatory transcription factor 1
 13043
 0.09
chr1_117079785_117079936 0.21 CD58
 CD58 molecule
 7352
 0.18
chr2_70775363_70775514 0.21 TGFA
 transforming growth factor, alpha
 5184
 0.25
chr8_142427041_142427192 0.21 PTP4A3
 protein tyrosine phosphatase type IVA, member 3
 4891
 0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 0.8 GO:0048541 Peyer's patch development(GO:0048541)
0.2 0.5 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1 0.4 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.3 GO:0009301 snRNA transcription(GO:0009301)
0.1 0.3 GO:0060157 urinary bladder development(GO:0060157)
0.1 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.4 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.1 0.3 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.2 GO:0001779 natural killer cell differentiation(GO:0001779)
0.1 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.1 0.3 GO:0007549 dosage compensation(GO:0007549)
0.1 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.1 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.5 GO:1901663 quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.2 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.3 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0014002 astrocyte development(GO:0014002)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0071028 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0021955 central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0010829 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0090196 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.1 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.2 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0039694 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.0 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.3 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0008228 opsonization(GO:0008228)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.3 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.5 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.9 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.9 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.2 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling