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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZKSCAN3

Z-value: 1.48

Motif logo

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Transcription factors associated with ZKSCAN3

Gene Symbol Gene ID Gene Info
ZKSCAN3
ENSG00000189298.9 zinc finger with KRAB and SCAN domains 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_28317524_28317690ZKSCAN3840.9607240.088.3e-01Click!
chr6_28317691_28318186ZKSCAN32110.915228-0.049.1e-01Click!

Activity of the ZKSCAN3 motif across conditions

Conditions sorted by the z-value of the ZKSCAN3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_56408975_56409725 1.69 MIR142
 microRNA 142
 519
 0.63
chr17_76126911_76127107 1.48 TMC8
 transmembrane channel-like 8
 140
 0.63
chrX_128914916_128915218 1.20 SASH3
 SAM and SH3 domain containing 3
 1107
 0.52
chr5_118607055_118607314 1.15 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 2735
 0.27
chr20_56193926_56194226 1.10 ZBP1
 Z-DNA binding protein 1
 1374
 0.49
chr14_76009252_76009829 1.08 BATF
 basic leucine zipper transcription factor, ATF-like
 20637
 0.15
chr1_1148809_1149188 1.00 TNFRSF4
 tumor necrosis factor receptor superfamily, member 4
 514
 0.56
chr11_3860110_3860464 0.96 RHOG
 ras homolog family member G
 1190
 0.3
chr4_6918537_6918793 0.88 TBC1D14
 TBC1 domain family, member 14
 6690
 0.19
chr2_136872491_136872642 0.85 CXCR4
 chemokine (C-X-C motif) receptor 4
 1247
 0.6
chr16_70452884_70453127 0.84 ST3GAL2
 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
 18464
 0.11
chr20_826059_826564 0.80 FAM110A
 family with sequence similarity 110, member A
 544
 0.82
chr3_9821738_9821889 0.75 CAMK1
 calcium/calmodulin-dependent protein kinase I
 10137
 0.09
chr20_50158730_50159057 0.75 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 365
 0.92
chr2_169103559_169103719 0.73 STK39
 serine threonine kinase 39
 1012
 0.7
chr1_7763805_7764045 0.72 CAMTA1
 calmodulin binding transcription activator 1
 32543
 0.17
chr14_24640773_24641022 0.70 REC8
 REC8 meiotic recombination protein
 165
 0.84
chr3_43332584_43332867 0.70 SNRK
 SNF related kinase
 4647
 0.21
chr1_211509571_211509738 0.70 TRAF5
 TNF receptor-associated factor 5
 9475
 0.25
chr3_127392819_127392970 0.69 ABTB1
 ankyrin repeat and BTB (POZ) domain containing 1
 59
 0.97
chr13_30950896_30951047 0.68 KATNAL1
 katanin p60 subunit A-like 1
 69350
 0.11
chr18_21601315_21601466 0.68 TTC39C
 tetratricopeptide repeat domain 39C
 4792
 0.19
chr4_154448881_154449032 0.67 KIAA0922
 KIAA0922
 28092
 0.22
chr17_45812399_45812645 0.67 TBX21
 T-box 21
 1912
 0.27
chrY_22738367_22738527 0.66 EIF1AY
 eukaryotic translation initiation factor 1A, Y-linked
 767
 0.8
chr4_42657844_42658977 0.66 ATP8A1
 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
 700
 0.59
chr9_20379288_20379439 0.64 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
 3104
 0.27
chr17_33640471_33640814 0.62 SLFN11
 schlafen family member 11
 39508
 0.12
chr20_31069881_31070147 0.62 C20orf112
 chromosome 20 open reading frame 112
 1260
 0.46
chr1_62862864_62863015 0.61 USP1
 ubiquitin specific peptidase 1
 39029
 0.17
chr2_71292065_71292344 0.61 AC007040.8
331
 0.79
chr11_46140422_46140573 0.60 PHF21A
 PHD finger protein 21A
 841
 0.64
chr1_9690042_9690512 0.60 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 21513
 0.15
chr19_42703347_42703984 0.59 ENSG00000265122
 .
 6435
 0.1
chr3_81692511_81692662 0.59 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 100194
 0.09
chr2_152326029_152326180 0.59 NEB
 nebulin
 33839
 0.18
chr14_94429340_94429491 0.59 ASB2
 ankyrin repeat and SOCS box containing 2
 5648
 0.17
chr14_78108377_78108627 0.59 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 25386
 0.16
chr8_22876543_22876783 0.59 RP11-875O11.1
185
 0.92
chr6_30458735_30458886 0.59 HLA-E
 major histocompatibility complex, class I, E
 1566
 0.31
chr9_71650379_71650667 0.58 FXN
 frataxin
 44
 0.98
chr9_129485287_129485658 0.55 ENSG00000266403
 .
 4860
 0.26
chr7_75267461_75267701 0.54 HIP1
 huntingtin interacting protein 1
 26420
 0.17
chr11_58291916_58292352 0.53 OR5B21
 olfactory receptor, family 5, subfamily B, member 21
 16556
 0.16
chr2_103035996_103036147 0.52 IL18RAP
 interleukin 18 receptor accessory protein
 75
 0.96
chr16_14379797_14380077 0.52 ENSG00000201075
 .
 10575
 0.18
chr2_198063557_198063736 0.51 ANKRD44
 ankyrin repeat domain 44
 884
 0.43
chr10_97516050_97516539 0.51 ENTPD1
 ectonucleoside triphosphate diphosphohydrolase 1
 580
 0.8
chr10_121276029_121276279 0.49 RGS10
 regulator of G-protein signaling 10
 10835
 0.24
chr12_66585349_66585521 0.49 IRAK3
 interleukin-1 receptor-associated kinase 3
 2398
 0.25
chr9_34122956_34123107 0.48 DCAF12
 DDB1 and CUL4 associated factor 12
 2694
 0.22
chr10_115613974_115614183 0.48 DCLRE1A
 DNA cross-link repair 1A
 64
 0.82
chr1_226926024_226926994 0.48 ITPKB
 inositol-trisphosphate 3-kinase B
 355
 0.91
chr12_49374311_49374525 0.48 WNT1
 wingless-type MMTV integration site family, member 1
 2020
 0.12
chrX_153672104_153672338 0.48 FAM50A
 family with sequence similarity 50, member A
 252
 0.79
chr8_66752287_66752671 0.47 PDE7A
 phosphodiesterase 7A
 1264
 0.6
chr20_58515606_58515958 0.46 FAM217B
 family with sequence similarity 217, member B
 288
 0.62
chr3_47028874_47029030 0.45 CCDC12
 coiled-coil domain containing 12
 5480
 0.19
chr13_49787907_49788058 0.45 MLNR
 motilin receptor
 6492
 0.24
chr21_47971505_47971656 0.45 ENSG00000272283
 .
 15871
 0.17
chr2_191744870_191745300 0.45 GLS
 glutaminase
 468
 0.79
chr21_34395985_34396161 0.45 OLIG2
 oligodendrocyte lineage transcription factor 2
 2080
 0.33
chr3_122512790_122513032 0.44 HSPBAP1
 HSPB (heat shock 27kDa) associated protein 1
 240
 0.82
chr22_50311854_50312054 0.44 CRELD2
 cysteine-rich with EGF-like domains 2
 139
 0.51
chr19_45595083_45595471 0.44 PPP1R37
 protein phosphatase 1, regulatory subunit 37
 941
 0.32
chr2_231533080_231533231 0.44 CAB39
 calcium binding protein 39
 44405
 0.14
chr12_123372500_123372784 0.43 VPS37B
 vacuolar protein sorting 37 homolog B (S. cerevisiae)
 2064
 0.29
chr6_157970217_157970368 0.42 ENSG00000266617
 .
 20128
 0.23
chr1_149294050_149294201 0.42 ENSG00000252105
 .
 7803
 0.17
chr4_185741986_185742137 0.42 ACSL1
 acyl-CoA synthetase long-chain family member 1
 5127
 0.2
chr1_185083987_185084138 0.41 TRMT1L
 tRNA methyltransferase 1 homolog (S. cerevisiae)-like
 24630
 0.18
chr11_117198864_117199680 0.41 CEP164
 centrosomal protein 164kDa
 453
 0.5
chr9_139000986_139001191 0.41 C9orf69
 chromosome 9 open reading frame 69
 9032
 0.19
chr15_41624315_41624466 0.41 OIP5
 Opa interacting protein 5
 295
 0.65
chr2_85107193_85107344 0.40 TRABD2A
 TraB domain containing 2A
 938
 0.57
chr16_23689854_23690079 0.40 PLK1
 polo-like kinase 1
 177
 0.92
chr14_50366151_50366383 0.40 ENSG00000251929
 .
 2401
 0.2
chr6_158980808_158981008 0.40 TMEM181
 transmembrane protein 181
 23440
 0.19
chr2_10548605_10548929 0.40 HPCAL1
 hippocalcin-like 1
 11380
 0.19
chr17_29158612_29158825 0.39 ATAD5
 ATPase family, AAA domain containing 5
 270
 0.86
chr1_180982153_180982304 0.39 STX6
 syntaxin 6
 9777
 0.16
chr16_84801882_84802033 0.39 USP10
 ubiquitin specific peptidase 10
 84
 0.98
chr12_8125010_8125161 0.39 ENSG00000206636
 .
 3770
 0.2
chr7_35731550_35731936 0.39 HERPUD2
 HERPUD family member 2
 2433
 0.31
chr8_21776103_21776686 0.39 XPO7
 exportin 7
 786
 0.64
chr7_150178540_150178691 0.38 GIMAP8
 GTPase, IMAP family member 8
 30897
 0.13
chr19_23427286_23427437 0.38 ZNF724P
 zinc finger protein 724, pseudogene
 5801
 0.26
chr8_37754904_37755445 0.38 RAB11FIP1
 RAB11 family interacting protein 1 (class I)
 1798
 0.27
chrX_144516660_144516811 0.38 SPANXN1
 SPANX family, member N1
 188387
 0.03
chr16_27326766_27327107 0.38 IL4R
 interleukin 4 receptor
 1623
 0.4
chr12_77060372_77060523 0.37 ZDHHC17
 zinc finger, DHHC-type containing 17
 96921
 0.08
chr15_91428804_91428955 0.37 FES
 feline sarcoma oncogene
 603
 0.56
chr2_42333200_42333351 0.37 PKDCC
 protein kinase domain containing, cytoplasmic
 58115
 0.11
chr19_7198675_7198826 0.37 INSR
 insulin receptor
 30761
 0.15
chr6_90538863_90539246 0.37 ENSG00000238747
 .
 6040
 0.17
chr5_14581323_14581785 0.36 FAM105A
 family with sequence similarity 105, member A
 330
 0.92
chr11_125773182_125774068 0.36 PUS3
 pseudouridylate synthase 3
 509
 0.49
chr7_26564902_26565053 0.36 KIAA0087
 KIAA0087
 13430
 0.27
chr12_113573231_113573417 0.36 RASAL1
 RAS protein activator like 1 (GAP1 like)
 15
 0.96
chr12_7064003_7064154 0.36 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
 3540
 0.07
chr15_83777071_83777287 0.36 TM6SF1
 transmembrane 6 superfamily member 1
 716
 0.58
chr7_92464516_92465198 0.35 AC002454.1
940
 0.44
chr17_75451832_75452118 0.35 SEPT9
 septin 9
 473
 0.77
chr1_153204493_153204644 0.35 PRR9
 proline rich 9
 14508
 0.12
chr12_104682714_104682980 0.35 TXNRD1
 thioredoxin reductase 1
 174
 0.95
chr8_53851957_53852159 0.35 NPBWR1
 neuropeptides B/W receptor 1
 1067
 0.63
chr12_105379814_105380296 0.35 C12orf45
 chromosome 12 open reading frame 45
 33
 0.98
chr11_73091522_73091673 0.35 RELT
 RELT tumor necrosis factor receptor
 3884
 0.17
chr19_2702225_2702378 0.34 GNG7
 guanine nucleotide binding protein (G protein), gamma 7
 406
 0.76
chr19_9649363_9649620 0.34 ZNF426
 zinc finger protein 426
 188
 0.94
chr1_149679650_149680105 0.34 FAM231D
 family with sequence similarity 231, member D
 3899
 0.14
chr1_26485721_26485872 0.34 FAM110D
 family with sequence similarity 110, member D
 285
 0.83
chr9_131486813_131486981 0.34 RP11-545E17.3
173
 0.76
chr6_32935556_32936303 0.34 BRD2
 bromodomain containing 2
 508
 0.51
chr10_86559929_86560080 0.34 ENSG00000238469
 .
 63017
 0.16
chr10_104953208_104953414 0.33 NT5C2
 5'-nucleotidase, cytosolic II
 255
 0.93
chr19_50269466_50269673 0.33 AP2A1
 adaptor-related protein complex 2, alpha 1 subunit
 656
 0.43
chr10_98346955_98347114 0.33 TM9SF3
 transmembrane 9 superfamily member 3
 175
 0.95
chr17_27942135_27942628 0.33 CORO6
 coronin 6
 2754
 0.11
chr1_226842452_226842603 0.33 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 4844
 0.24
chr9_115095390_115095852 0.32 PTBP3
 polypyrimidine tract binding protein 3
 237
 0.93
chr11_10826698_10826955 0.32 EIF4G2
 eukaryotic translation initiation factor 4 gamma, 2
 2183
 0.2
chr19_18209757_18210181 0.32 IL12RB1
 interleukin 12 receptor, beta 1
 215
 0.88
chr14_22591595_22591746 0.32 ENSG00000238634
 .
 19217
 0.26
chr17_54912094_54912323 0.32 DGKE
 diacylglycerol kinase, epsilon 64kDa
 119
 0.92
chr17_58041207_58042016 0.31 RNFT1
 ring finger protein, transmembrane 1
 469
 0.76
chr4_6200889_6201238 0.31 JAKMIP1
 janus kinase and microtubule interacting protein 1
 1219
 0.6
chr3_178866443_178867773 0.31 PIK3CA
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
 207
 0.94
chr17_40729951_40730261 0.31 PSMC3IP
 PSMC3 interacting protein
 257
 0.81
chr4_152787665_152787816 0.31 ENSG00000253077
 .
 105025
 0.07
chr6_90061473_90061759 0.30 UBE2J1
 ubiquitin-conjugating enzyme E2, J1
 951
 0.59
chr14_89925846_89925997 0.30 FOXN3
 forkhead box N3
 34474
 0.15
chr12_7995756_7996489 0.30 ENSG00000222978
 .
 3762
 0.15
chr20_47365732_47365883 0.30 ENSG00000251876
 .
 9822
 0.28
chr19_21646219_21646922 0.30 ZNF429
 zinc finger protein 429
 41796
 0.16
chr7_142161599_142161750 0.30 PRSS3P3
 protease, serine, 3 pseudogene 3
 172065
 0.03
chr14_24550083_24550870 0.29 NRL
 neural retina leucine zipper
 661
 0.47
chr3_71730862_71731013 0.29 EIF4E3
 eukaryotic translation initiation factor 4E family member 3
 43589
 0.15
chr19_59049656_59050353 0.29 ZBTB45
 zinc finger and BTB domain containing 45
 274
 0.78
chr1_212340351_212340502 0.29 ENSG00000252879
 .
 67408
 0.09
chr3_171825160_171825429 0.29 FNDC3B
 fibronectin type III domain containing 3B
 19470
 0.26
chr1_150536035_150536186 0.29 ADAMTSL4-AS1
 ADAMTSL4 antisense RNA 1
 2141
 0.14
chr16_89043094_89043288 0.29 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
 210
 0.92
chr6_32159535_32159686 0.29 GPSM3
 G-protein signaling modulator 3
 1035
 0.26
chr17_4336857_4337447 0.29 SPNS3
 spinster homolog 3 (Drosophila)
 67
 0.97
chr20_5584278_5584429 0.28 GPCPD1
 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
 7319
 0.28
chr16_30486681_30486832 0.28 ITGAL
 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
 1434
 0.16
chr11_134200417_134200568 0.28 GLB1L2
 galactosidase, beta 1-like 2
 1276
 0.47
chr17_14332143_14332294 0.28 HS3ST3B1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
 127818
 0.06
chr2_106388828_106388979 0.28 NCK2
 NCK adaptor protein 2
 26715
 0.24
chr19_18606740_18606891 0.28 ELL
 elongation factor RNA polymerase II
 20072
 0.09
chr15_65476466_65477266 0.28 CLPX
 caseinolytic mitochondrial matrix peptidase chaperone subunit
 44
 0.97
chr13_41576254_41576405 0.28 ELF1
 E74-like factor 1 (ets domain transcription factor)
 17121
 0.19
chr4_184312949_184313100 0.27 ENSG00000263395
 .
 7318
 0.18
chr11_75063727_75063930 0.27 ARRB1
 arrestin, beta 1
 955
 0.48
chr5_1501743_1501894 0.27 LPCAT1
 lysophosphatidylcholine acyltransferase 1
 22274
 0.2
chr5_171061425_171061576 0.27 ENSG00000264303
 .
 136034
 0.04
chr22_21024096_21024247 0.27 ENSG00000264718
 .
 12849
 0.14
chr1_28415312_28415525 0.27 EYA3
 eyes absent homolog 3 (Drosophila)
 211
 0.92
chr11_125461662_125462346 0.27 STT3A
 STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
 397
 0.49
chr1_161185105_161185306 0.27 FCER1G
 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
 118
 0.89
chr7_75543939_75544219 0.26 POR
 P450 (cytochrome) oxidoreductase
 318
 0.58
chr6_32144901_32145530 0.26 AGPAT1
 1-acylglycerol-3-phosphate O-acyltransferase 1
 113
 0.87
chr2_240207404_240207640 0.26 ENSG00000265215
 .
 19635
 0.17
chr1_225966293_225966491 0.26 SRP9
 signal recognition particle 9kDa
 755
 0.6
chr18_47003055_47003217 0.26 RP11-110H1.4
9383
 0.08
chr10_105667946_105668135 0.26 OBFC1
 oligonucleotide/oligosaccharide-binding fold containing 1
 9387
 0.18
chr9_132647660_132648047 0.26 FNBP1
 formin binding protein 1
 33736
 0.12
chr6_44042101_44042381 0.25 RP5-1120P11.1
148
 0.95
chr1_233463556_233464041 0.25 MLK4
 Mitogen-activated protein kinase kinase kinase MLK4
 284
 0.94
chr15_66993020_66993328 0.25 SMAD6
 SMAD family member 6
 1392
 0.51
chr21_34671674_34671958 0.25 IFNAR1
 interferon (alpha, beta and omega) receptor 1
 24918
 0.13
chr6_126067758_126068417 0.25 HEY2
 hes-related family bHLH transcription factor with YRPW motif 2
 723
 0.57
chr1_67518540_67519349 0.25 SLC35D1
 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
 214
 0.95
chr1_22351357_22351739 0.25 ENSG00000201273
 .
 14070
 0.09
chrX_39953289_39953491 0.25 BCOR
 BCL6 corepressor
 3266
 0.39
chr16_30393182_30393494 0.25 SEPT1
 septin 1
 414
 0.64
chr8_101320634_101321676 0.25 RNF19A
 ring finger protein 19A, RBR E3 ubiquitin protein ligase
 599
 0.79
chr12_131246546_131246697 0.25 RIMBP2
 RIMS binding protein 2
 45795
 0.14
chr17_67322489_67323211 0.25 ABCA5
 ATP-binding cassette, sub-family A (ABC1), member 5
 381
 0.89
chr2_216945952_216946469 0.25 PECR
 peroxisomal trans-2-enoyl-CoA reductase
 329
 0.53
chr7_8181769_8181920 0.25 ENSG00000265212
 .
 12808
 0.21
chr1_226593332_226593483 0.25 PARP1
 poly (ADP-ribose) polymerase 1
 2276
 0.33
chr7_155089675_155090099 0.24 INSIG1
 insulin induced gene 1
 288
 0.92
chrX_153775545_153775808 0.24 G6PD
 glucose-6-phosphate dehydrogenase
 96
 0.49
chr6_143165995_143166218 0.24 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 7922
 0.29
chr7_75796315_75796558 0.24 AC005077.5
6615
 0.18
chr3_71773124_71773375 0.24 EIF4E3
 eukaryotic translation initiation factor 4E family member 3
 1277
 0.5
chr1_101749663_101749814 0.24 RP4-575N6.5
41024
 0.13
chr9_95791041_95791204 0.24 FGD3
 FYVE, RhoGEF and PH domain containing 3
 13780
 0.18
chrX_117631127_117631452 0.24 DOCK11
 dedicator of cytokinesis 11
 1417
 0.52
chr17_72463483_72463716 0.24 CD300A
 CD300a molecule
 598
 0.68
chr12_124873885_124874250 0.23 NCOR2
 nuclear receptor corepressor 2
 697
 0.79
chr5_77160779_77160930 0.23 TBCA
 tubulin folding cofactor A
 3750
 0.36
chr19_17622493_17622725 0.23 PGLS
 6-phosphogluconolactonase
 65
 0.94
chr1_149898902_149899634 0.23 SF3B4
 splicing factor 3b, subunit 4, 49kDa
 215
 0.86
chr3_182511875_182512794 0.23 ATP11B
 ATPase, class VI, type 11B
 1043
 0.43
chr2_28824878_28825070 0.23 PLB1
 phospholipase B1
 188
 0.96
chr10_89628293_89628531 0.23 KLLN
 killin, p53-regulated DNA replication inhibitor
 5218
 0.15
chr17_74489731_74490033 0.23 RHBDF2
 rhomboid 5 homolog 2 (Drosophila)
 598
 0.59

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.6 GO:0090201 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.1 0.6 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.1 0.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0072540 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.6 GO:0007141 male meiosis I(GO:0007141)
0.1 0.2 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.5 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0006168 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.0 GO:0051569 regulation of histone methylation(GO:0031060) regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.2 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.7 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.1 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0061054 dermatome development(GO:0061054)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.3 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.3 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:1904377 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0051299 centrosome separation(GO:0051299)
0.0 0.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.3 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.0 GO:0022038 cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030) corpus callosum development(GO:0022038)
0.0 0.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:0045117 azole transport(GO:0045117)
0.0 0.2 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.9 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.0 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.0 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.0 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.0 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0019835 cytolysis(GO:0019835)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0000800 lateral element(GO:0000800)
0.1 0.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.4 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1 0.4 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0005814 centriole(GO:0005814)
0.0 0.0 GO:0001739 sex chromatin(GO:0001739)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.0 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.2 GO:0019863 IgE binding(GO:0019863)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.5 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 1.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21