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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF148

Z-value: 0.94

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Transcription factors associated with ZNF148

Gene Symbol Gene ID Gene Info
ZNF148
ENSG00000163848.14 ZNF148

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ZNF148chr3_125092923_1250936098270.637282-0.636.9e-02Click!
ZNF148chr3_125086590_12508678974040.2071390.452.2e-01Click!
ZNF148chr3_125092460_12509261115580.404423-0.363.4e-01Click!
ZNF148chr3_125076195_1250766942180.943425-0.333.8e-01Click!
ZNF148chr3_125094287_1250949424160.8504360.314.1e-01Click!

Activity of the ZNF148 motif across conditions

Conditions sorted by the z-value of the ZNF148 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrX_8698839_8699470 0.61 KAL1
 Kallmann syndrome 1 sequence
 1073
 0.66
chr10_118031771_118032060 0.59 GFRA1
 GDNF family receptor alpha 1
 121
 0.98
chr12_48109642_48109793 0.55 ENDOU
 endonuclease, polyU-specific
 1715
 0.32
chr11_131780761_131781452 0.53 NTM
 neurotrimin
 209
 0.95
chr12_117799295_117799446 0.49 NOS1
 nitric oxide synthase 1 (neuronal)
 212
 0.96
chr18_6729547_6730123 0.48 ARHGAP28
 Rho GTPase activating protein 28
 14
 0.5
chr19_11253525_11253809 0.48 SPC24
 SPC24, NDC80 kinetochore complex component
 12770
 0.13
chr14_105830576_105830747 0.47 PACS2
 phosphofurin acidic cluster sorting protein 2
 18795
 0.13
chr17_73718374_73718525 0.45 ITGB4
 integrin, beta 4
 872
 0.43
chr4_74809740_74810515 0.44 PF4
 platelet factor 4
 37714
 0.11
chr6_10383738_10384217 0.44 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
 20850
 0.18
chr1_3390049_3390200 0.43 ARHGEF16
 Rho guanine nucleotide exchange factor (GEF) 16
 1936
 0.35
chr2_9347772_9348251 0.43 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 1117
 0.65
chr6_125684588_125685144 0.43 RP11-735G4.1
10604
 0.27
chr10_126029940_126030091 0.42 OAT
 ornithine aminotransferase
 77490
 0.1
chr5_71403321_71403664 0.42 MAP1B
 microtubule-associated protein 1B
 179
 0.97
chr6_3455456_3455921 0.42 SLC22A23
 solute carrier family 22, member 23
 589
 0.84
chr17_3848324_3848628 0.41 ATP2A3
 ATPase, Ca++ transporting, ubiquitous
 14811
 0.16
chr10_118764443_118765166 0.41 KIAA1598
 KIAA1598
 72
 0.98
chr1_27336321_27336472 0.40 FAM46B
 family with sequence similarity 46, member B
 2931
 0.22
chr14_105116453_105116770 0.40 ENSG00000265291
 .
 27475
 0.12
chr10_133850335_133850615 0.39 BNIP3
 BCL2/adenovirus E1B 19kDa interacting protein 3
 55040
 0.13
chr6_43252045_43252196 0.39 SLC22A7
 solute carrier family 22 (organic anion transporter), member 7
 13616
 0.13
chr1_10891240_10891391 0.39 CASZ1
 castor zinc finger 1
 34608
 0.18
chr11_65666484_65666730 0.38 FOSL1
 FOS-like antigen 1
 1283
 0.23
chr4_53729260_53729411 0.38 RASL11B
 RAS-like, family 11, member B
 878
 0.66
chr14_104007555_104007706 0.37 ENSG00000252469
 .
 9052
 0.08
chr19_49652849_49653066 0.37 PPFIA3
 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
 1599
 0.2
chr2_167232459_167233133 0.37 SCN9A
 sodium channel, voltage-gated, type IX, alpha subunit
 293
 0.93
chr16_15236302_15236453 0.37 ENSG00000207294
 .
 8177
 0.11
chr12_7076786_7076937 0.37 ENSG00000238795
 .
 92
 0.69
chr5_141258225_141258866 0.37 PCDH1
 protocadherin 1
 266
 0.92
chr8_143224078_143224229 0.37 ENSG00000265247
 .
 33547
 0.19
chr19_33884880_33885031 0.37 CEBPG
 CCAAT/enhancer binding protein (C/EBP), gamma
 19737
 0.19
chr9_124360553_124361088 0.37 RP11-524G24.2
22327
 0.18
chr1_17274725_17274876 0.37 CROCC
 ciliary rootlet coiled-coil, rootletin
 25550
 0.12
chr16_2174847_2175247 0.36 RP11-304L19.2
5839
 0.06
chr8_72459619_72459990 0.36 RP11-1102P16.1
 Uncharacterized protein
 88
 0.98
chr13_52165897_52166092 0.36 ENSG00000242893
 .
 2357
 0.21
chr2_86055147_86055298 0.36 ENSG00000252321
 .
 7487
 0.17
chr16_4373749_4373941 0.36 GLIS2
 GLIS family zinc finger 2
 8380
 0.13
chr17_46103279_46103479 0.36 COPZ2
 coatomer protein complex, subunit zeta 2
 7859
 0.09
chr19_17225078_17225229 0.35 MYO9B
 myosin IXB
 12625
 0.11
chr16_54321004_54321411 0.35 IRX3
 iroquois homeobox 3
 532
 0.83
chr10_120739922_120740073 0.35 RP11-498J9.2
23399
 0.15
chr8_144501585_144501736 0.35 RP11-909N17.3
1811
 0.21
chr3_13869046_13869197 0.34 WNT7A
 wingless-type MMTV integration site family, member 7A
 52497
 0.13
chr3_139654401_139654885 0.34 CLSTN2
 calsyntenin 2
 616
 0.84
chr10_35102956_35103650 0.34 PARD3
 par-3 family cell polarity regulator
 946
 0.5
chr1_156890393_156890693 0.34 LRRC71
 leucine rich repeat containing 71
 101
 0.95
chr7_139899946_139900413 0.34 ENSG00000199971
 .
 9292
 0.16
chr5_6767017_6767234 0.34 PAPD7
 PAP associated domain containing 7
 52380
 0.15
chr12_49689580_49689731 0.34 PRPH
 peripherin
 510
 0.66
chr6_155586253_155586446 0.33 CLDN20
 claudin 20
 1202
 0.49
chr17_43205399_43205692 0.33 PLCD3
 phospholipase C, delta 3
 4346
 0.12
chr7_124404967_124405458 0.33 GPR37
 G protein-coupled receptor 37 (endothelin receptor type B-like)
 469
 0.88
chr8_144653425_144654110 0.33 MROH6
 maestro heat-like repeat family member 6
 1151
 0.21
chr2_160918347_160919586 0.33 PLA2R1
 phospholipase A2 receptor 1, 180kDa
 155
 0.98
chr2_242504094_242504245 0.33 BOK-AS1
 BOK antisense RNA 1
 5777
 0.13
chr17_16977527_16977700 0.33 MPRIP-AS1
 MPRIP antisense RNA 1
 3453
 0.23
chr4_1798938_1799089 0.33 FGFR3
 fibroblast growth factor receptor 3
 3390
 0.22
chr6_150246697_150247451 0.32 RAET1G
 retinoic acid early transcript 1G
 2817
 0.17
chr19_33784339_33784950 0.32 CTD-2540B15.11
6196
 0.14
chr11_45202678_45203014 0.32 PRDM11
 PR domain containing 11
 582
 0.81
chr17_15168005_15168252 0.31 PMP22
 peripheral myelin protein 22
 496
 0.74
chr21_44774072_44774359 0.31 SIK1
 salt-inducible kinase 1
 72793
 0.11
chr14_69015254_69015531 0.31 CTD-2325P2.4
79770
 0.1
chr22_46287338_46287489 0.31 WNT7B
 wingless-type MMTV integration site family, member 7B
 81182
 0.07
chr7_100464814_100466140 0.31 TRIP6
 thyroid hormone receptor interactor 6
 717
 0.47
chr3_65779704_65779855 0.31 MAGI1-AS1
 MAGI1 antisense RNA 1
 99712
 0.08
chr10_128594353_128594780 0.31 DOCK1
 dedicator of cytokinesis 1
 588
 0.8
chr8_61936210_61936526 0.31 CLVS1
 clavesin 1
 33349
 0.24
chr5_68710635_68711790 0.31 MARVELD2
 MARVEL domain containing 2
 3
 0.97
chr15_31734664_31735087 0.30 KLF13
 Kruppel-like factor 13
 76518
 0.12
chr16_89895218_89895373 0.30 SPIRE2
 spire-type actin nucleation factor 2
 340
 0.84
chr20_60892287_60892438 0.30 RP11-157P1.4
10981
 0.12
chr11_118489826_118490091 0.29 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 11600
 0.11
chr12_122235363_122235779 0.29 RHOF
 ras homolog family member F (in filopodia)
 3012
 0.21
chr16_4369635_4369919 0.29 GLIS2
 GLIS family zinc finger 2
 5015
 0.15
chr2_131594534_131594685 0.29 AC133785.1
42
 0.87
chr7_1577374_1577649 0.29 MAFK
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
 833
 0.54
chrX_114795286_114795437 0.29 PLS3
 plastin 3
 148
 0.94
chr16_12995514_12995665 0.29 SHISA9
 shisa family member 9
 25
 0.98
chr1_155102531_155102783 0.29 EFNA1
 ephrin-A1
 2305
 0.11
chr8_22723308_22723535 0.29 RP11-87E22.2
12064
 0.17
chr14_71355414_71355574 0.29 PCNX
 pecanex homolog (Drosophila)
 18628
 0.26
chr16_85253495_85253759 0.29 CTC-786C10.1
48745
 0.15
chr1_1356913_1357064 0.28 ANKRD65
 ankyrin repeat domain 65
 161
 0.85
chr1_956379_957022 0.28 AGRN
 agrin
 1197
 0.27
chr17_46131994_46132145 0.28 NFE2L1
 nuclear factor, erythroid 2-like 1
 3
 0.95
chr19_675778_676178 0.28 FSTL3
 follistatin-like 3 (secreted glycoprotein)
 414
 0.71
chr11_12108503_12108884 0.28 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 6850
 0.29
chr7_100660155_100661047 0.28 RP11-395B7.4
281
 0.85
chr15_90605491_90605664 0.28 ZNF710
 zinc finger protein 710
 5669
 0.16
chr17_39676556_39676707 0.27 KRT15
 keratin 15
 640
 0.5
chr7_45002030_45002849 0.27 RP4-647J21.1
1931
 0.25
chr4_715649_715800 0.27 RP11-1191J2.4
2099
 0.18
chr19_38494188_38494741 0.27 CTC-244M17.1
39971
 0.13
chr14_31343280_31344466 0.27 COCH
 cochlin
 78
 0.97
chr2_95742439_95743056 0.27 AC103563.9
23826
 0.15
chr22_50740529_50740680 0.27 PLXNB2
 plexin B2
 713
 0.47
chr1_92495646_92496322 0.27 EPHX4
 epoxide hydrolase 4
 445
 0.85
chr1_19250411_19250700 0.27 IFFO2
 intermediate filament family orphan 2
 12069
 0.16
chr1_16343782_16344178 0.27 HSPB7
 heat shock 27kDa protein family, member 7 (cardiovascular)
 340
 0.8
chr1_109969825_109970028 0.26 PSMA5
 proteasome (prosome, macropain) subunit, alpha type, 5
 864
 0.52
chr9_140111635_140112002 0.26 RNF208
 ring finger protein 208
 3957
 0.07
chr12_125002282_125002834 0.26 NCOR2
 nuclear receptor corepressor 2
 282
 0.95
chr20_48606144_48606295 0.26 SNAI1
 snail family zinc finger 1
 6683
 0.17
chr17_35207376_35207682 0.26 RP11-445F12.1
86392
 0.07
chr6_49518031_49518578 0.26 C6orf141
 chromosome 6 open reading frame 141
 191
 0.95
chr6_43704451_43704602 0.26 VEGFA
 vascular endothelial growth factor A
 33424
 0.12
chr9_130318193_130318378 0.26 FAM129B
 family with sequence similarity 129, member B
 13082
 0.17
chr7_70079490_70079756 0.26 AUTS2
 autism susceptibility candidate 2
 114502
 0.07
chr2_157176521_157176855 0.26 NR4A2
 nuclear receptor subfamily 4, group A, member 2
 9945
 0.27
chr21_40393056_40393282 0.26 ENSG00000272015
 .
 126460
 0.05
chr5_131594297_131594770 0.26 PDLIM4
 PDZ and LIM domain 4
 1133
 0.45
chr1_201228727_201229116 0.26 PKP1
 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
 23659
 0.15
chr19_3097024_3097175 0.26 GNA11
 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
 2691
 0.16
chr6_36684370_36684521 0.26 RAB44
 RAB44, member RAS oncogene family
 1189
 0.44
chr22_38291029_38291180 0.26 ENSG00000207227
 .
 3750
 0.12
chr19_1748372_1748523 0.25 ONECUT3
 one cut homeobox 3
 3925
 0.16
chr1_1369498_1369649 0.25 VWA1
 von Willebrand factor A domain containing 1
 668
 0.44
chr1_156092284_156092708 0.25 LMNA
 lamin A/C
 3455
 0.14
chr1_17914943_17915229 0.25 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 175
 0.97
chr19_1789718_1789869 0.25 ATP8B3
 ATPase, aminophospholipid transporter, class I, type 8B, member 3
 21830
 0.09
chr18_77218683_77219016 0.25 AC018445.1
 Uncharacterized protein
 57208
 0.13
chr1_27425556_27426394 0.25 SLC9A1
 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
 54998
 0.1
chr20_36915633_36915784 0.25 BPI
 bactericidal/permeability-increasing protein
 16817
 0.15
chr16_68772325_68772476 0.25 CDH1
 cadherin 1, type 1, E-cadherin (epithelial)
 1145
 0.43
chr6_150070946_150071995 0.25 PCMT1
 protein-L-isoaspartate (D-aspartate) O-methyltransferase
 290
 0.87
chr8_27491561_27492240 0.25 SCARA3
 scavenger receptor class A, member 3
 202
 0.93
chr7_123672325_123672477 0.25 RP5-921G16.1
142
 0.93
chr12_49942443_49943296 0.25 KCNH3
 potassium voltage-gated channel, subfamily H (eag-related), member 3
 9929
 0.13
chr17_836473_836730 0.25 RP11-676J12.7
 Uncharacterized protein
 23729
 0.14
chr17_75283624_75283888 0.25 SEPT9
 septin 9
 217
 0.95
chr6_153303042_153303631 0.25 FBXO5
 F-box protein 5
 817
 0.52
chr1_53951416_53951567 0.25 DMRTB1
 DMRT-like family B with proline-rich C-terminal, 1
 26419
 0.21
chr9_124527262_124527413 0.24 DAB2IP
 DAB2 interacting protein
 22273
 0.22
chr22_50312384_50313103 0.24 CRELD2
 cysteine-rich with EGF-like domains 2
 362
 0.66
chr1_208374584_208374735 0.24 PLXNA2
 plexin A2
 43006
 0.22
chr14_105436556_105437076 0.24 AHNAK2
 AHNAK nucleoprotein 2
 7878
 0.16
chr11_707284_707470 0.24 EPS8L2
 EPS8-like 2
 748
 0.42
chr17_20746972_20747807 0.24 RP11-344E13.4
11870
 0.17
chr20_822913_823164 0.24 FAM110A
 family with sequence similarity 110, member A
 2247
 0.36
chr19_2461781_2462465 0.24 LMNB2
 lamin B2
 5129
 0.15
chr10_79396627_79397649 0.24 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
 67
 0.98
chr19_57350948_57351186 0.23 PEG3
 paternally expressed 3
 997
 0.38
chr1_153536795_153537072 0.23 S100A2
 S100 calcium binding protein A2
 224
 0.84
chr3_131079896_131080531 0.23 ENSG00000250608
 .
 242
 0.76
chr9_22006120_22006693 0.23 CDKN2B
 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
 2546
 0.22
chr3_30140484_30140635 0.23 ENSG00000264178
 .
 39180
 0.18
chr2_159825200_159826543 0.23 TANC1
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
 688
 0.73
chr2_208370253_208370617 0.23 CREB1
 cAMP responsive element binding protein 1
 24026
 0.19
chr2_113882342_113882741 0.23 IL1RN
 interleukin 1 receptor antagonist
 2597
 0.21
chr4_2935171_2936035 0.23 MFSD10
 major facilitator superfamily domain containing 10
 71
 0.94
chr1_32166523_32166715 0.22 COL16A1
 collagen, type XVI, alpha 1
 3149
 0.19
chr19_13112715_13112989 0.22 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 6200
 0.09
chr11_72451789_72452038 0.22 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
 11535
 0.12
chr1_159842521_159842672 0.22 RP11-190A12.8
5852
 0.1
chr12_102454924_102455862 0.22 CCDC53
 coiled-coil domain containing 53
 464
 0.76
chr1_225117342_225117684 0.22 DNAH14
 dynein, axonemal, heavy chain 14
 129
 0.98
chr12_3069053_3070004 0.22 TEAD4
 TEA domain family member 4
 445
 0.77
chr17_80288187_80288338 0.22 SECTM1
 secreted and transmembrane 1
 1880
 0.21
chr1_43201434_43201585 0.22 CLDN19
 claudin 19
 4302
 0.16
chr5_175828477_175828628 0.22 NOP16
 NOP16 nucleolar protein
 12576
 0.1
chr16_88877375_88878305 0.22 APRT
 adenine phosphoribosyltransferase
 465
 0.66
chr15_74724718_74725429 0.22 SEMA7A
 semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
 928
 0.5
chr5_38845474_38846010 0.22 OSMR
 oncostatin M receptor
 218
 0.96
chr1_38510289_38510696 0.22 POU3F1
 POU class 3 homeobox 1
 1958
 0.27
chr13_33858654_33859881 0.22 STARD13
 StAR-related lipid transfer (START) domain containing 13
 625
 0.76
chr8_23204118_23204478 0.22 ENSG00000253837
 .
 10577
 0.16
chr9_34578314_34578465 0.22 CNTFR-AS1
 CNTFR antisense RNA 1
 8800
 0.1
chr2_231692712_231693467 0.21 ITM2C
 integral membrane protein 2C
 36265
 0.14
chr1_110518577_110518847 0.21 AHCYL1
 adenosylhomocysteinase-like 1
 8596
 0.18
chr4_25031967_25032301 0.21 LGI2
 leucine-rich repeat LGI family, member 2
 153
 0.97
chr5_167719768_167719973 0.21 WWC1
 WW and C2 domain containing 1
 715
 0.76
chr19_39466589_39467071 0.21 FBXO17
 F-box protein 17
 280
 0.84
chr2_1597607_1597758 0.21 AC144450.1
26203
 0.23
chr6_129203821_129204789 0.21 LAMA2
 laminin, alpha 2
 37
 0.99
chr4_175135564_175135744 0.21 FBXO8
 F-box protein 8
 69160
 0.12
chr17_47091251_47091425 0.21 RP11-501C14.6
251
 0.85
chr2_103104653_103104941 0.21 SLC9A4
 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
 15035
 0.18
chr14_71022448_71023169 0.21 ADAM20
 ADAM metallopeptidase domain 20
 21076
 0.17
chr9_116356336_116356765 0.21 RGS3
 regulator of G-protein signaling 3
 784
 0.67
chr19_1241899_1242560 0.21 ATP5D
 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
 410
 0.68
chr7_22538999_22539909 0.21 STEAP1B
 STEAP family member 1B
 342
 0.91
chr3_45076964_45077591 0.21 ENSG00000252410
 .
 1197
 0.45
chr4_81189244_81189728 0.21 FGF5
 fibroblast growth factor 5
 1693
 0.45
chr3_55516545_55517089 0.21 WNT5A
 wingless-type MMTV integration site family, member 5A
 1396
 0.5
chr1_50061585_50061736 0.21 AGBL4-IT1
 AGBL4 intronic transcript 1 (non-protein coding)
 123903
 0.06
chr22_47149775_47150260 0.21 CTA-29F11.1
8443
 0.18
chr17_46674549_46675551 0.21 HOXB-AS3
 HOXB cluster antisense RNA 3
 1249
 0.2
chr20_43970794_43971114 0.21 SDC4
 syndecan 4
 6110
 0.13
chr19_12949779_12950060 0.21 MAST1
 microtubule associated serine/threonine kinase 1
 571
 0.48
chr3_184209968_184210530 0.21 EIF2B5-IT1
 EIF2B5 intronic transcript 1 (non-protein coding)
 12652
 0.18
chr11_22214479_22215097 0.20 ANO5
 anoctamin 5
 66
 0.98
chr1_33546740_33547295 0.20 ADC
 arginine decarboxylase
 249
 0.93
chr9_139025166_139025528 0.20 C9orf69
 chromosome 9 open reading frame 69
 14616
 0.18
chr11_10757586_10757776 0.20 ENSG00000206858
 .
 10231
 0.15
chr17_881575_881780 0.20 NXN
 nucleoredoxin
 1333
 0.34

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ZNF148

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.5 GO:0060068 vagina development(GO:0060068)
0.1 0.5 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0032288 myelin assembly(GO:0032288)
0.1 0.2 GO:0046084 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.1 0.1 GO:0001705 ectoderm formation(GO:0001705)
0.1 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.2 GO:0071875 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.1 GO:0003171 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0070977 organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.2 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0060433 bronchus development(GO:0060433)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0045079 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.1 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.2 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.1 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0060761 negative regulation of response to cytokine stimulus(GO:0060761)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.4 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.4 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0099518 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.2 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0048243 regulation of norepinephrine secretion(GO:0014061) norepinephrine secretion(GO:0048243)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0032823 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0007143 female meiotic division(GO:0007143)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.2 GO:0038061 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0 0.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0072283 mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) mesenchymal to epithelial transition(GO:0060231) renal vesicle morphogenesis(GO:0072077) metanephric renal vesicle morphogenesis(GO:0072283)
0.0 0.0 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.0 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0045911 positive regulation of DNA recombination(GO:0045911)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0044447 axoneme part(GO:0044447)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.2 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.0 GO:0022839 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.1 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo