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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF232

Z-value: 0.35

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Transcription factors associated with ZNF232

Gene Symbol	Gene ID	Gene Info
ZNF232 Ensembl NCBI GeneCards UniProt	ENSG00000167840.9	ZNF232

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZNF232	chr17_5025984_5026458	176	0.905187	-0.36	3.4e-01	Click!
ZNF232	chr17_5025740_5025978	538	0.633731	-0.30	4.4e-01	Click!
ZNF232	chr17_5026549_5026700	227	0.873778	-0.28	4.6e-01	Click!
ZNF232	chr17_5014924_5015118	115	0.617372	0.17	6.6e-01	Click!

Activity of the ZNF232 motif across conditions

Conditions sorted by the z-value of the ZNF232 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_130883505_130884015	0.20	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	15034	0.29
chr12_94544055_94544362	0.19	PLXNC1	plexin C1	1709	0.42
chr2_113432534_113432708	0.17	SLC20A1	solute carrier family 20 (phosphate transporter), member 1	27342	0.16
chr1_111416320_111416529	0.15	CD53	CD53 molecule	648	0.73
chr6_105405546_105405738	0.15	LIN28B	lin-28 homolog B (C. elegans)	719	0.75
chr10_11206019_11206557	0.15	CELF2	CUGBP, Elav-like family member 2	705	0.72
chr3_151961203_151961354	0.14	MBNL1	muscleblind-like splicing regulator 1	24551	0.2
chr2_160711557_160711708	0.14	LY75	lymphocyte antigen 75	49561	0.13
chr20_52538846_52539125	0.14	AC005220.3		17714	0.25
chr7_150148744_150149359	0.13	GIMAP8	GTPase, IMAP family member 8	1333	0.41
chr3_46995163_46995374	0.13	CCDC12	coiled-coil domain containing 12	23002	0.14
chr3_19189181_19189385	0.13	KCNH8	potassium voltage-gated channel, subfamily H (eag-related), member 8	663	0.83
chr19_35927435_35927735	0.12	FFAR2	free fatty acid receptor 2	11618	0.11
chr3_108205436_108205587	0.12	MYH15	myosin, heavy chain 15	42658	0.16
chr9_102972411_102972625	0.12	ENSG00000239908	.	107677	0.06
chr15_34609178_34609329	0.12	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6	1727	0.23
chr12_80265785_80265936	0.12	PPP1R12A	protein phosphatase 1, regulatory subunit 12A	792	0.63
chr18_18685949_18686100	0.12	ROCK1	Rho-associated, coiled-coil containing protein kinase 1	5788	0.23
chr1_40844474_40844625	0.11	SMAP2	small ArfGAP2	4229	0.21
chr2_43232738_43232956	0.11	ENSG00000207087	.	85785	0.1
chr10_14603489_14603761	0.11	FAM107B	family with sequence similarity 107, member B	5446	0.27
chr7_50350563_50350714	0.11	IKZF1	IKAROS family zinc finger 1 (Ikaros)	2320	0.42
chr3_30715119_30715270	0.11	RP11-1024P17.1		23959	0.25
chr1_50575996_50576351	0.11	ELAVL4	ELAV like neuron-specific RNA binding protein 4	795	0.71
chr22_30234443_30234651	0.11	ASCC2	activating signal cointegrator 1 complex subunit 2	282	0.9
chr3_19188036_19188187	0.11	KCNH8	potassium voltage-gated channel, subfamily H (eag-related), member 8	1835	0.51
chr14_92340111_92340262	0.11	FBLN5	fibulin 5	4200	0.23
chr8_92051530_92051722	0.10	TMEM55A	transmembrane protein 55A	1437	0.31
chr7_15620685_15620964	0.10	AGMO	alkylglycerol monooxygenase	19184	0.26
chr13_27825183_27825382	0.10	RPL21	ribosomal protein L21	164	0.92
chr10_134150291_134150926	0.10	LRRC27	leucine rich repeat containing 27	236	0.93
chr12_116716284_116716544	0.10	MED13L	mediator complex subunit 13-like	1271	0.52
chr1_24828022_24828241	0.10	RCAN3	RCAN family member 3	1256	0.44
chr2_66673742_66673893	0.10	MEIS1	Meis homeobox 1	3720	0.19
chr5_126094487_126094638	0.09	ENSG00000252185	.	3453	0.28
chr1_40848271_40848430	0.09	SMAP2	small ArfGAP2	8030	0.18
chr13_41553714_41553865	0.09	ELF1	E74-like factor 1 (ets domain transcription factor)	2629	0.29
chr22_30268883_30269034	0.09	MTMR3	myotubularin related protein 3	10186	0.16
chrX_130875960_130876221	0.09	ENSG00000200587	.	196894	0.03
chr5_39199802_39200193	0.09	FYB	FYN binding protein	3132	0.36
chr18_9102187_9102500	0.09	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	285	0.9
chr6_149866537_149867090	0.09	PPIL4	peptidylprolyl isomerase (cyclophilin)-like 4	361	0.81
chr2_232650134_232650432	0.09	PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	699	0.46
chrX_123096191_123096863	0.09	STAG2	stromal antigen 2	493	0.85
chr1_78443552_78443956	0.09	FUBP1	far upstream element (FUSE) binding protein 1	991	0.46
chr1_205283585_205283736	0.09	NUAK2	NUAK family, SNF1-like kinase, 2	7223	0.17
chr6_110796871_110797126	0.09	SLC22A16	solute carrier family 22 (organic cation/carnitine transporter), member 16	601	0.69
chr17_56412846_56413076	0.09	ENSG00000264399	.	422	0.69
chr14_91709116_91709392	0.09	CTD-2547L24.3	HCG1816139; Uncharacterized protein	25	0.97
chr8_53627211_53627825	0.09	RB1CC1	RB1-inducible coiled-coil 1	492	0.84
chrX_77166269_77166668	0.09	ATP7A	ATPase, Cu++ transporting, alpha polypeptide	269	0.89
chr6_26198173_26198564	0.09	HIST1H3D	histone cluster 1, H3d	890	0.22
chr5_98362367_98362646	0.09	ENSG00000200351	.	90055	0.09
chr22_38784304_38784455	0.08	RP1-5O6.4		483	0.72
chr5_49735948_49736099	0.08	EMB	embigin	1161	0.67
chr10_74146912_74147063	0.08	ENSG00000202513	.	4735	0.23
chr1_158773010_158773161	0.08	OR6N2	olfactory receptor, family 6, subfamily N, member 2	25660	0.13
chr1_169675171_169675322	0.08	SELL	selectin L	5593	0.21
chr12_68383559_68383710	0.08	IFNG-AS1	IFNG antisense RNA 1	325	0.94
chr17_30471048_30471199	0.08	AC090616.2	Uncharacterized protein	969	0.38
chr1_231665268_231665468	0.08	TSNAX	translin-associated factor X	967	0.41
chr12_6446702_6447173	0.08	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	4077	0.14
chr7_151039214_151039888	0.08	NUB1	negative regulator of ubiquitin-like proteins 1	653	0.66
chrX_78417451_78417673	0.08	GPR174	G protein-coupled receptor 174	8907	0.32
chrX_77154989_77155623	0.08	COX7B	cytochrome c oxidase subunit VIIb	371	0.82
chr1_22401714_22401865	0.08	CDC42-IT1	CDC42 intronic transcript 1 (non-protein coding)	16099	0.13
chrX_8150685_8150836	0.08	VCX2	variable charge, X-linked 2	11452	0.28
chr2_10472002_10472153	0.08	HPCAL1	hippocalcin-like 1	28251	0.15
chr8_124049779_124050367	0.07	TBC1D31	TBC1 domain family, member 31	4135	0.17
chr14_90084669_90085459	0.07	FOXN3	forkhead box N3	410	0.78
chr12_51321341_51321492	0.07	METTL7A	methyltransferase like 7A	2882	0.21
chr19_55020488_55020639	0.07	LAIR2	leukocyte-associated immunoglobulin-like receptor 2	6440	0.11
chr1_38314226_38314377	0.07	MTF1	metal-regulatory transcription factor 1	10991	0.09
chr9_67232492_67232789	0.07	ENSG00000265601	.	7188	0.28
chr15_45878869_45879476	0.07	BLOC1S6	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	149	0.75
chr6_109416364_109416609	0.07	CEP57L1	centrosomal protein 57kDa-like 1	95	0.86
chr3_148995184_148995347	0.07	RP11-206M11.7		7304	0.21
chr7_30067058_30067509	0.07	PLEKHA8	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8	695	0.49
chr9_88420732_88421441	0.07	AGTPBP1	ATP/GTP binding protein 1	64142	0.15
chr3_18478950_18479101	0.07	SATB1	SATB homeobox 1	1159	0.53
chr13_21649079_21649364	0.07	LATS2	large tumor suppressor kinase 2	13535	0.15
chr1_169679248_169679951	0.07	SELL	selectin L	1240	0.48
chr11_35066286_35066437	0.07	PDHX	pyruvate dehydrogenase complex, component X	67030	0.1
chr9_273424_273720	0.07	DOCK8	dedicator of cytokinesis 8	502	0.5
chrX_10066246_10067411	0.07	WWC3	WWC family member 3	35329	0.15
chr4_109901499_109901650	0.07	COL25A1	collagen, type XXV, alpha 1	156199	0.04
chr5_1345378_1345625	0.07	CLPTM1L	CLPTM1-like	287	0.91
chr13_50715497_50715648	0.07	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	59265	0.12
chr11_121340288_121340439	0.07	RP11-730K11.1		16641	0.23
chr19_39341392_39342222	0.07	HNRNPL	heterogeneous nuclear ribonucleoprotein L	12	0.94
chr1_234614976_234615210	0.07	TARBP1	TAR (HIV-1) RNA binding protein 1	244	0.94
chr20_57738915_57739179	0.07	ZNF831	zinc finger protein 831	27028	0.21
chr10_120489799_120489950	0.07	CACUL1	CDK2-associated, cullin domain 1	24884	0.21
chr14_22321778_22321996	0.07	ENSG00000222776	.	73102	0.11
chr20_33733027_33733178	0.07	EDEM2	ER degradation enhancer, mannosidase alpha-like 2	143	0.94
chr3_21788653_21788804	0.07	ZNF385D	zinc finger protein 385D	4199	0.35
chr2_66806799_66806950	0.07	MEIS1	Meis homeobox 1	70815	0.12
chr21_32556834_32556985	0.07	TIAM1	T-cell lymphoma invasion and metastasis 1	54370	0.16
chr7_76236072_76236223	0.07	POMZP3	POM121 and ZP3 fusion	11470	0.2
chr11_33907227_33907391	0.07	AC132216.1	HCG1785179; PRO1787; Uncharacterized protein	5120	0.22
chr4_94755757_94755908	0.07	ATOH1	atonal homolog 1 (Drosophila)	5790	0.27
chr1_247095902_247096053	0.07	AHCTF1	AT hook containing transcription factor 1	697	0.73
chr12_32115176_32115327	0.07	KIAA1551	KIAA1551	172	0.96
chr12_29435079_29435230	0.07	RP11-996F15.2		35627	0.16
chr16_12523462_12523613	0.06	RP11-165M1.2		56857	0.11
chr12_11962518_11962720	0.06	ETV6	ets variant 6	57184	0.16
chr1_202937217_202937368	0.06	CYB5R1	cytochrome b5 reductase 1	884	0.46
chr10_65024685_65024930	0.06	JMJD1C	jumonji domain containing 1C	4019	0.32
chr19_54871270_54871421	0.06	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	1211	0.31
chr20_62535769_62535920	0.06	ENSG00000199805	.	4464	0.08
chr5_143267127_143267278	0.06	HMHB1	histocompatibility (minor) HB-1	75476	0.12
chr4_73232259_73232410	0.06	RP11-373J21.1		43589	0.21
chr1_198620819_198621442	0.06	PTPRC	protein tyrosine phosphatase, receptor type, C	12838	0.23
chr20_48321626_48321777	0.06	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	8714	0.2
chr9_80850286_80850511	0.06	CEP78	centrosomal protein 78kDa	580	0.83
chr11_65408305_65408462	0.06	SIPA1	signal-induced proliferation-associated 1	84	0.92
chr16_74331532_74331708	0.06	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	893	0.6
chr9_67087582_67087733	0.06	ENSG00000265285	.	7276	0.31
chr5_87798376_87798680	0.06	TMEM161B-AS1	TMEM161B antisense RNA 1	76016	0.11
chr1_72347063_72347214	0.06	NEGR1-IT1	NEGR1 intronic transcript 1 (non-protein coding)	44443	0.21
chr1_154378708_154379562	0.06	RP11-350G8.5		95	0.93
chrX_131158192_131158580	0.06	MST4	Serine/threonine-protein kinase MST4	750	0.71
chr1_160548800_160549253	0.06	CD84	CD84 molecule	237	0.91
chr14_100873124_100873275	0.06	RP11-362L22.1		43	0.96
chr7_30323590_30323942	0.06	ZNRF2	zinc and ring finger 2	157	0.96
chr17_8867884_8868296	0.06	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	934	0.65
chr15_72665455_72665606	0.06	HEXA	hexosaminidase A (alpha polypeptide)	2655	0.21
chr8_8861066_8861441	0.06	ERI1	exoribonuclease 1	899	0.57
chr2_101921816_101922067	0.06	RNF149	ring finger protein 149	3217	0.21
chr2_170591300_170591489	0.06	KLHL23	kelch-like family member 23	668	0.64
chr19_9545439_9546179	0.06	ZNF266	zinc finger protein 266	60	0.97
chr15_69707071_69708026	0.06	RP11-253M7.1		180	0.86
chr18_2659017_2659168	0.06	SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1	3206	0.21
chr10_134068601_134068752	0.06	STK32C	serine/threonine kinase 32C	52042	0.12
chr13_45058136_45058287	0.06	TSC22D1	TSC22 domain family, member 1	9825	0.29
chr2_190133275_190133426	0.06	ENSG00000266817	.	43137	0.17
chr15_99395675_99396414	0.06	IGF1R	insulin-like growth factor 1 receptor	37526	0.16
chr4_141075455_141075656	0.06	MAML3	mastermind-like 3 (Drosophila)	217	0.95
chr1_42230218_42230369	0.06	ENSG00000264896	.	5481	0.3
chr3_127842347_127842602	0.06	RUVBL1	RuvB-like AAA ATPase 1	169	0.94
chr1_232726179_232726330	0.06	SIPA1L2	signal-induced proliferation-associated 1 like 2	28950	0.24
chr4_38857928_38858431	0.06	TLR6	toll-like receptor 6	258	0.48
chr14_45719805_45719966	0.06	MIS18BP1	MIS18 binding protein 1	2495	0.3
chr20_31484373_31484524	0.06	EFCAB8	EF-hand calcium binding domain 8	15011	0.18
chr2_54221778_54222027	0.06	ACYP2	acylphosphatase 2, muscle type	23657	0.18
chr8_59977467_59977618	0.05	RP11-25K19.1		54057	0.13
chr6_106534568_106534850	0.05	PRDM1	PR domain containing 1, with ZNF domain	514	0.83
chr3_14557562_14557713	0.05	ENSG00000207163	.	14958	0.22
chr9_31422111_31422262	0.05	ENSG00000211510	.	647960	0.0
chr17_60140816_60141064	0.05	MED13	mediator complex subunit 13	1703	0.35
chr4_48342236_48343218	0.05	SLAIN2	SLAIN motif family, member 2	612	0.8
chrX_24043946_24044693	0.05	KLHL15	kelch-like family member 15	984	0.59
chrY_2482600_2482989	0.05	ENSG00000251841	.	169996	0.04
chr9_42914569_42914720	0.05	AC129778.2		55559	0.15
chr6_111202605_111202756	0.05	AMD1	adenosylmethionine decarboxylase 1	5902	0.17
chr7_114565895_114566046	0.05	MDFIC	MyoD family inhibitor domain containing	2839	0.42
chr1_159925204_159925355	0.05	SLAMF9	SLAM family member 9	1235	0.32
chr8_117664337_117664488	0.05	EIF3H	eukaryotic translation initiation factor 3, subunit H	103611	0.07
chr3_119811066_119811419	0.05	GSK3B	glycogen synthase kinase 3 beta	1271	0.47
chr10_65028344_65028625	0.05	JMJD1C	jumonji domain containing 1C	342	0.93
chr10_111769664_111769909	0.05	ADD3	adducin 3 (gamma)	2064	0.33
chr1_167298272_167298450	0.05	POU2F1	POU class 2 homeobox 1	80	0.98
chr20_5588883_5589774	0.05	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	2344	0.4
chr2_24577017_24577377	0.05	ITSN2	intersectin 2	5981	0.25
chr6_57039244_57039395	0.05	RP11-203B9.4		285	0.85
chr7_130789448_130789720	0.05	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	2205	0.33
chr10_124713000_124713296	0.05	C10orf88	chromosome 10 open reading frame 88	771	0.61
chr2_232526451_232526617	0.05	ENSG00000239202	.	15550	0.16
chrX_78619893_78620072	0.05	ITM2A	integral membrane protein 2A	2874	0.42
chr3_20145563_20145846	0.05	ENSG00000266745	.	33353	0.15
chr15_50568045_50568196	0.05	HDC	histidine decarboxylase	9897	0.15
chr16_87096172_87096484	0.05	RP11-899L11.3		153193	0.04
chr8_52783217_52783484	0.05	PCMTD1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	25045	0.15
chr13_110810904_110811055	0.05	ENSG00000265885	.	60481	0.14
chr5_69586650_69586865	0.05	GTF2H2B	general transcription factor IIH, polypeptide 2B (pseudogene)	124422	0.06
chr5_15718526_15718677	0.05	FBXL7	F-box and leucine-rich repeat protein 7	102510	0.08
chr16_21612011_21612297	0.05	METTL9	methyltransferase like 9	1275	0.35
chr11_111444678_111444829	0.05	SIK2	salt-inducible kinase 2	28362	0.11
chr5_69882192_69882402	0.05	RP11-497H16.7		113022	0.07
chr11_18127000_18127190	0.05	SAAL1	serum amyloid A-like 1	471	0.74
chr1_101650998_101651149	0.05	ENSG00000238296	.	43248	0.11
chrX_55479729_55479880	0.05	MAGEH1	melanoma antigen family H, 1	1266	0.4
chr5_69006919_69007136	0.05	GUSBP3	glucuronidase, beta pseudogene 3	686	0.78
chr6_41042589_41042740	0.05	NFYA	nuclear transcription factor Y, alpha	1942	0.21
chr4_143224062_143224213	0.05	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	2848	0.43
chr10_27529985_27530175	0.05	ACBD5	acyl-CoA binding domain containing 5	301	0.85
chr14_78081630_78082591	0.05	SPTLC2	serine palmitoyltransferase, long chain base subunit 2	1006	0.56
chr5_70014898_70015115	0.05	SERF1A	small EDRK-rich factor 1A (telomeric)	181486	0.03
chr11_102320072_102320223	0.05	TMEM123	transmembrane protein 123	36	0.97
chr5_95144147_95144466	0.05	GLRX	glutaredoxin (thioltransferase)	14109	0.14
chr5_180671226_180671377	0.05	GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	92	0.87
chr13_74067154_74067305	0.05	ENSG00000206697	.	265945	0.02
chr2_159074611_159074762	0.05	CCDC148-AS1	CCDC148 antisense RNA 1	51524	0.15
chr12_120974205_120974387	0.05	RNF10	ring finger protein 10	1067	0.34
chr2_265229_265468	0.05	ACP1	acid phosphatase 1, soluble	422	0.54
chr2_45004927_45005078	0.05	ENSG00000252896	.	4267	0.35
chr13_43566462_43567025	0.05	EPSTI1	epithelial stromal interaction 1 (breast)	358	0.92
chr21_16579081_16579232	0.05	NRIP1	nuclear receptor interacting protein 1	141835	0.05
chr5_70586170_70586382	0.05	PMCHL2	pro-melanin-concentrating hormone-like 2, pseudogene	85381	0.09
chr2_114655602_114655753	0.05	ACTR3	ARP3 actin-related protein 3 homolog (yeast)	7502	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF232

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	GO:0032060	bleb assembly(GO:0032060)
0.1	GO:0060235	lens induction in camera-type eye(GO:0060235)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)