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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZNF282

Z-value: 1.42

Motif logo

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ZNF282
ENSG00000170265.7 zinc finger protein 282

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_148888070_148888331ZNF28243770.1819380.684.5e-02Click!
chr7_148878257_148878408ZNF282142450.143314-0.674.6e-02Click!
chr7_148893161_148893454ZNF2826650.6600050.636.9e-02Click!
chr7_148893506_148893991ZNF28211060.4561580.412.8e-01Click!
chr7_148888671_148888822ZNF28238310.1908400.402.8e-01Click!

Activity of the ZNF282 motif across conditions

Conditions sorted by the z-value of the ZNF282 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_46572021_46572172 0.77 SLC38A1
 solute carrier family 38, member 1
 89388
 0.1
chr17_39969662_39969906 0.65 FKBP10
 FK506 binding protein 10, 65 kDa
 601
 0.45
chr11_119954135_119954286 0.55 TRIM29
 tripartite motif containing 29
 37398
 0.19
chr7_100771927_100772106 0.49 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 1637
 0.23
chr16_58534463_58534728 0.48 NDRG4
 NDRG family member 4
 545
 0.68
chr11_119953003_119953290 0.48 TRIM29
 tripartite motif containing 29
 38462
 0.18
chr7_1959519_1959814 0.45 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 20519
 0.22
chr5_125936367_125936518 0.44 PHAX
 phosphorylated adaptor for RNA export
 482
 0.79
chr1_88798905_88799056 0.42 ENSG00000239504
 .
 144817
 0.05
chr5_67512014_67512283 0.42 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 544
 0.82
chr15_94544847_94544998 0.42 ENSG00000212022
 .
 79498
 0.11
chr2_74780571_74780754 0.42 LOXL3
 lysyl oxidase-like 3
 400
 0.5
chr8_96307989_96308140 0.42 C8orf37
 chromosome 8 open reading frame 37
 26635
 0.24
chr11_18719924_18720222 0.41 TMEM86A
 transmembrane protein 86A
 265
 0.89
chr5_137688953_137689239 0.41 KDM3B
 lysine (K)-specific demethylase 3B
 811
 0.51
chr1_150971821_150972085 0.41 FAM63A
 family with sequence similarity 63, member A
 1307
 0.24
chr1_163038601_163039117 0.41 RGS4
 regulator of G-protein signaling 4
 76
 0.98
chr3_25471806_25472309 0.41 RARB
 retinoic acid receptor, beta
 2255
 0.41
chr6_10748064_10748484 0.41 TMEM14B
 transmembrane protein 14B
 210
 0.53
chr21_38711081_38711320 0.40 AP001437.1
27034
 0.16
chr8_55294341_55294557 0.39 ENSG00000244107
 .
 38579
 0.17
chrX_100074585_100074736 0.39 CSTF2
 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
 724
 0.63
chr20_50045192_50045343 0.39 ENSG00000266761
 .
 24247
 0.22
chr1_226069091_226069419 0.38 TMEM63A
 transmembrane protein 63A
 814
 0.51
chr10_11865085_11865286 0.38 PROSER2
 proline and serine-rich protein 2
 212
 0.95
chr12_77719208_77719557 0.38 ENSG00000238769
 .
 162577
 0.04
chr2_161491867_161492018 0.38 RBMS1
 RNA binding motif, single stranded interacting protein 1
 141637
 0.05
chrX_46432817_46433047 0.38 CHST7
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
 287
 0.92
chr2_157189525_157189762 0.37 NR4A2
 nuclear receptor subfamily 4, group A, member 2
 411
 0.9
chr2_145276293_145276624 0.37 ZEB2-AS1
 ZEB2 antisense RNA 1
 434
 0.52
chr10_114820084_114820658 0.37 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
 83308
 0.1
chr11_119954548_119954699 0.37 TRIM29
 tripartite motif containing 29
 36985
 0.19
chr20_57586431_57586603 0.37 CTSZ
 cathepsin Z
 4215
 0.17
chr3_16006218_16006514 0.37 ENSG00000207815
 .
 91088
 0.08
chr20_43150833_43151092 0.36 SERINC3
 serine incorporator 3
 212
 0.91
chr4_2486639_2486842 0.36 RNF4
 ring finger protein 4
 4798
 0.2
chr7_149572287_149572438 0.36 ATP6V0E2
 ATPase, H+ transporting V0 subunit e2
 1230
 0.35
chr1_197887720_197887871 0.36 LHX9
 LIM homeobox 9
 1266
 0.53
chr17_7121037_7121301 0.36 DLG4
 discs, large homolog 4 (Drosophila)
 503
 0.43
chr12_125412025_125412330 0.36 UBC
 ubiquitin C
 10263
 0.16
chr12_127256953_127257104 0.35 ENSG00000239776
 .
 393644
 0.01
chr9_96930088_96930349 0.35 ENSG00000199165
 .
 8016
 0.16
chr6_165722376_165722527 0.35 C6orf118
 chromosome 6 open reading frame 118
 109
 0.98
chr15_75471507_75471789 0.35 C15orf39
 chromosome 15 open reading frame 39
 16336
 0.13
chr1_161369629_161370065 0.35 ENSG00000206921
 .
 1232
 0.42
chr19_13977402_13977553 0.34 ENSG00000207613
 .
 8036
 0.08
chr2_225846726_225846877 0.34 ENSG00000263828
 .
 28456
 0.22
chr14_63672700_63672938 0.34 RHOJ
 ras homolog family member J
 1242
 0.54
chr20_21961725_21961876 0.34 PAX1
 paired box 1
 274939
 0.02
chrX_65220606_65220757 0.34 RP6-159A1.3
1088
 0.56
chr21_42739358_42739509 0.33 MX2
 myxovirus (influenza virus) resistance 2 (mouse)
 2579
 0.29
chr1_243646920_243647071 0.33 RP11-269F20.1
61839
 0.14
chr6_34358484_34358635 0.33 NUDT3
 nudix (nucleoside diphosphate linked moiety X)-type motif 3
 1892
 0.33
chr5_58335725_58336097 0.33 RP11-266N13.2
323
 0.69
chr8_13372824_13372975 0.33 DLC1
 deleted in liver cancer 1
 503
 0.82
chr12_65672666_65673070 0.33 MSRB3
 methionine sulfoxide reductase B3
 101
 0.97
chr7_93943609_93943760 0.33 COL1A2
 collagen, type I, alpha 2
 80189
 0.11
chr7_156687876_156688027 0.33 LMBR1
 limb development membrane protein 1
 2027
 0.34
chr9_116356768_116357019 0.33 RGS3
 regulator of G-protein signaling 3
 1127
 0.54
chrX_100183665_100184190 0.33 XKRX
 XK, Kell blood group complex subunit-related, X-linked
 29
 0.98
chr17_61722686_61722837 0.32 MAP3K3
 mitogen-activated protein kinase kinase kinase 3
 22691
 0.13
chrX_133687659_133687810 0.32 ENSG00000223749
 .
 6993
 0.12
chr20_8651278_8651429 0.32 ENSG00000222298
 .
 60466
 0.12
chr5_25569497_25569648 0.31 ENSG00000201016
 .
 131861
 0.06
chr2_242319557_242319708 0.31 FARP2
 FERM, RhoGEF and pleckstrin domain protein 2
 7368
 0.16
chr1_87223134_87223385 0.31 SH3GLB1
 SH3-domain GRB2-like endophilin B1
 52681
 0.12
chr1_226852545_226852696 0.31 ITPKB-AS1
 ITPKB antisense RNA 1
 3978
 0.24
chr12_2420181_2420332 0.31 CACNA1C-IT3
 CACNA1C intronic transcript 3 (non-protein coding)
 41314
 0.18
chr17_37844389_37844572 0.31 ERBB2
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
 87
 0.53
chr16_1979223_1979447 0.31 HS3ST6
 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
 10894
 0.06
chr11_82774150_82774358 0.31 RAB30
 RAB30, member RAS oncogene family
 8616
 0.18
chrY_6883288_6883439 0.31 TBL1Y
 transducin (beta)-like 1, Y-linked
 104636
 0.08
chr10_114206747_114206976 0.31 VTI1A
 vesicle transport through interaction with t-SNAREs 1A
 155
 0.54
chr15_41850580_41851004 0.31 TYRO3
 TYRO3 protein tyrosine kinase
 440
 0.79
chr12_113841803_113841954 0.31 SDS
 serine dehydratase
 185
 0.94
chrX_46616562_46616983 0.30 SLC9A7
 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
 1718
 0.46
chr19_13319063_13319297 0.30 CACNA1A
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 49034
 0.08
chr8_97170599_97170750 0.30 GDF6
 growth differentiation factor 6
 2346
 0.36
chr1_221342999_221343150 0.30 HLX
 H2.0-like homeobox
 288490
 0.01
chr10_89265401_89265555 0.30 MINPP1
 multiple inositol-polyphosphate phosphatase 1
 846
 0.69
chrY_19466305_19466456 0.30 ENSG00000252315
 .
 203364
 0.03
chr1_183605727_183605878 0.30 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
 558
 0.58
chr8_23571667_23572036 0.29 RP11-175E9.1
7197
 0.17
chr11_66444702_66445046 0.29 RBM4B
 RNA binding motif protein 4B
 345
 0.79
chr20_2451568_2451719 0.29 SNRPB
 small nuclear ribonucleoprotein polypeptides B and B1
 144
 0.94
chr15_62353285_62353511 0.29 RP11-643M14.1
685
 0.44
chr15_40234807_40235047 0.29 ENSG00000238564
 .
 7980
 0.15
chr11_119954900_119955051 0.28 TRIM29
 tripartite motif containing 29
 36633
 0.19
chr19_6110825_6111002 0.28 RFX2
 regulatory factor X, 2 (influences HLA class II expression)
 301
 0.84
chr8_37344900_37345051 0.28 RP11-150O12.6
29564
 0.23
chr17_46627635_46627871 0.28 HOXB-AS3
 HOXB cluster antisense RNA 3
 761
 0.38
chr1_86043929_86044119 0.28 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 91
 0.97
chr3_123477356_123477507 0.28 MYLK
 myosin light chain kinase
 35257
 0.15
chr14_61447182_61447373 0.28 TRMT5
 tRNA methyltransferase 5
 492
 0.5
chr17_63341710_63341861 0.28 ENSG00000265189
 .
 74993
 0.12
chr1_221910890_221911087 0.28 DUSP10
 dual specificity phosphatase 10
 186
 0.97
chr6_24667419_24667634 0.28 ACOT13
 acyl-CoA thioesterase 13
 227
 0.53
chr5_128429913_128430155 0.27 ISOC1
 isochorismatase domain containing 1
 410
 0.87
chr20_31988038_31988189 0.27 CDK5RAP1
 CDK5 regulatory subunit associated protein 1
 1210
 0.46
chr5_5419342_5419575 0.27 KIAA0947
 KIAA0947
 3349
 0.39
chr17_47077722_47077873 0.27 IGF2BP1
 insulin-like growth factor 2 mRNA binding protein 1
 2689
 0.14
chr14_58862127_58862433 0.26 RP11-517O13.3
79
 0.8
chr11_72449633_72449911 0.26 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
 11599
 0.12
chr9_107755904_107756060 0.26 ABCA1
 ATP-binding cassette, sub-family A (ABC1), member 1
 65464
 0.11
chr7_101930639_101930983 0.26 SH2B2
 SH2B adaptor protein 2
 2359
 0.2
chr10_53459424_53459629 0.26 CSTF2T
 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
 171
 0.97
chr11_118939891_118940176 0.25 VPS11
 vacuolar protein sorting 11 homolog (S. cerevisiae)
 1540
 0.15
chr15_93446443_93446658 0.25 ENSG00000264173
 .
 1079
 0.38
chr16_22202801_22203159 0.25 EEF2K
 eukaryotic elongation factor-2 kinase
 14623
 0.17
chr6_26313507_26313734 0.25 HIST1H4H
 histone cluster 1, H4h
 27858
 0.07
chr7_89896255_89896406 0.25 AC002064.4
3200
 0.19
chr6_133133816_133133967 0.25 RPS12
 ribosomal protein S12
 1689
 0.22
chr13_98112435_98112620 0.25 RAP2A
 RAP2A, member of RAS oncogene family
 26051
 0.24
chr8_32559587_32559738 0.25 NRG1
 neuregulin 1
 19609
 0.29
chr18_71857391_71857542 0.25 TIMM21
 translocase of inner mitochondrial membrane 21 homolog (yeast)
 35056
 0.15
chr7_131338473_131338624 0.25 PODXL
 podocalyxin-like
 97172
 0.08
chr4_81189028_81189189 0.25 FGF5
 fibroblast growth factor 5
 1315
 0.54
chr1_201857476_201857627 0.25 SHISA4
 shisa family member 4
 285
 0.85
chr1_90460194_90460489 0.25 ZNF326
 zinc finger protein 326
 333
 0.91
chr11_119953470_119953621 0.25 TRIM29
 tripartite motif containing 29
 38063
 0.18
chr1_109504839_109504990 0.25 CLCC1
 chloride channel CLIC-like 1
 1158
 0.34
chr12_52346063_52346405 0.25 ACVR1B
 activin A receptor, type IB
 706
 0.62
chr5_122110815_122111189 0.25 SNX2
 sorting nexin 2
 104
 0.94
chr8_27630129_27630324 0.25 CCDC25
 coiled-coil domain containing 25
 69
 0.89
chr5_172185603_172185754 0.25 RP11-779O18.1
449
 0.76
chrX_135848946_135849996 0.25 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 31
 0.98
chr1_240256340_240256520 0.25 FMN2
 formin 2
 1250
 0.57
chr9_125796489_125796713 0.25 GPR21
 G protein-coupled receptor 21
 205
 0.86
chr12_53846681_53847472 0.25 PCBP2
 poly(rC) binding protein 2
 448
 0.72
chr1_89591012_89591781 0.25 GBP2
 guanylate binding protein 2, interferon-inducible
 401
 0.85
chr22_40571850_40572001 0.24 TNRC6B
 trinucleotide repeat containing 6B
 2004
 0.43
chr15_79328270_79328421 0.24 RASGRF1
 Ras protein-specific guanine nucleotide-releasing factor 1
 30338
 0.17
chr16_66586477_66586958 0.24 CKLF-CMTM1
 CKLF-CMTM1 readthrough
 165
 0.44
chr6_146284922_146285161 0.24 SHPRH
 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
 192
 0.97
chr19_55765035_55765186 0.24 PPP6R1
 protein phosphatase 6, regulatory subunit 1
 2027
 0.15
chr17_18313829_18314117 0.24 AL353997.4
10160
 0.11
chr20_4954300_4954516 0.24 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 27737
 0.17
chrX_129065192_129065438 0.24 UTP14A
 UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
 17976
 0.18
chr4_140375324_140375815 0.24 RP11-83A24.2
381
 0.62
chr1_170640082_170640341 0.24 PRRX1
 paired related homeobox 1
 7133
 0.3
chr2_162849046_162849197 0.24 ENSG00000253046
 .
 73829
 0.1
chr7_114459536_114459687 0.24 MDFIC
 MyoD family inhibitor domain containing
 102598
 0.08
chr2_177042560_177043156 0.24 HOXD-AS1
 HOXD cluster antisense RNA 1
 5
 0.95
chr10_31608301_31608721 0.24 ENSG00000237036
 .
 109
 0.8
chr15_60898079_60898454 0.23 RORA
 RAR-related orphan receptor A
 12941
 0.23
chr5_154078594_154078745 0.23 ENSG00000263478
 .
 4675
 0.17
chr11_85358415_85358894 0.23 TMEM126A
 transmembrane protein 126A
 367
 0.83
chr12_68043814_68044335 0.23 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 612
 0.81
chr2_55647724_55647875 0.23 CCDC88A
 coiled-coil domain containing 88A
 742
 0.62
chrX_102631036_102631748 0.23 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
 57
 0.97
chr7_82201510_82201661 0.23 CACNA2D1
 calcium channel, voltage-dependent, alpha 2/delta subunit 1
 128471
 0.06
chr9_119713843_119714110 0.23 ENSG00000265662
 .
 147310
 0.04
chr19_10811895_10812062 0.23 QTRT1
 queuine tRNA-ribosyltransferase 1
 149
 0.93
chr13_99160815_99160995 0.23 STK24
 serine/threonine kinase 24
 10616
 0.23
chr20_12990547_12990774 0.23 SPTLC3
 serine palmitoyltransferase, long chain base subunit 3
 663
 0.83
chr15_64679591_64679870 0.23 TRIP4
 thyroid hormone receptor interactor 4
 273
 0.85
chr4_1241678_1241899 0.23 CTBP1
 C-terminal binding protein 1
 740
 0.5
chr20_9073959_9074110 0.23 PLCB4
 phospholipase C, beta 4
 24286
 0.22
chrX_87155513_87155664 0.23 ENSG00000252016
 .
 248205
 0.02
chr9_133712337_133712924 0.23 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 2177
 0.35
chr1_67600256_67600407 0.23 C1orf141
 chromosome 1 open reading frame 141
 308
 0.89
chr12_133404529_133404680 0.22 GOLGA3
 golgin A3
 684
 0.62
chr18_20274804_20275027 0.22 RP11-370A5.1
36613
 0.17
chr6_132179827_132179978 0.22 ENSG00000200895
 .
 38428
 0.14
chr1_206645642_206645925 0.22 IKBKE
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
 1945
 0.27
chr3_155393866_155394017 0.22 PLCH1
 phospholipase C, eta 1
 113
 0.98
chr3_16927344_16927610 0.22 PLCL2
 phospholipase C-like 2
 1025
 0.65
chr19_16461941_16462107 0.22 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 10740
 0.14
chr20_48955472_48955638 0.22 ENSG00000244376
 .
 90465
 0.08
chr1_163845312_163845463 0.22 ENSG00000212538
 .
 47520
 0.2
chr2_175546375_175546968 0.22 WIPF1
 WAS/WASL interacting protein family, member 1
 928
 0.66
chr12_49450678_49450829 0.22 KMT2D
 lysine (K)-specific methyltransferase 2D
 1646
 0.2
chr12_125473806_125474002 0.22 DHX37
 DEAH (Asp-Glu-Ala-His) box polypeptide 37
 237
 0.93
chr1_12139606_12139757 0.22 ENSG00000201135
 .
 1640
 0.3
chr14_103481209_103481581 0.22 CDC42BPB
 CDC42 binding protein kinase beta (DMPK-like)
 42404
 0.13
chr8_75234014_75234228 0.22 JPH1
 junctophilin 1
 558
 0.76
chr5_175788940_175789140 0.22 KIAA1191
 KIAA1191
 69
 0.94
chr15_34627792_34628213 0.21 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
 1043
 0.38
chr20_13619088_13619556 0.21 TASP1
 taspase, threonine aspartase, 1
 228
 0.96
chr8_124829666_124829817 0.21 FER1L6
 fer-1-like 6 (C. elegans)
 34486
 0.17
chr11_111957062_111957410 0.21 SDHD
 succinate dehydrogenase complex, subunit D, integral membrane protein
 261
 0.49
chr3_125931550_125931701 0.21 ALDH1L1-AS2
 ALDH1L1 antisense RNA 2
 5527
 0.19
chr5_14983876_14984027 0.21 ENSG00000212036
 .
 73202
 0.11
chr3_177624174_177624369 0.21 ENSG00000199858
 .
 101296
 0.09
chrX_12992120_12992286 0.21 TMSB4X
 thymosin beta 4, X-linked
 1024
 0.6
chrX_118924681_118925547 0.21 RPL39
 ribosomal protein L39
 492
 0.74
chr2_216286742_216286974 0.21 FN1
 fibronectin 1
 13932
 0.21
chr2_241497193_241497674 0.21 ANKMY1
 ankyrin repeat and MYND domain containing 1
 5
 0.96
chr21_35748199_35748651 0.21 SMIM11
 small integral membrane protein 11
 522
 0.54
chr5_168167573_168167764 0.21 ENSG00000207739
 .
 27592
 0.17
chr12_47219516_47219750 0.21 SLC38A4
 solute carrier family 38, member 4
 135
 0.98
chr18_60520045_60520196 0.21 AC015989.2
14172
 0.2
chr4_119201779_119201930 0.21 ENSG00000269893
 .
 1509
 0.54
chr7_143083179_143083339 0.21 ZYX
 zyxin
 3166
 0.14
chr15_83420399_83420550 0.21 RP11-752G15.6
1138
 0.35
chr19_47731656_47732088 0.20 ENSG00000265134
 .
 1673
 0.27
chr18_72162856_72163393 0.20 CNDP2
 CNDP dipeptidase 2 (metallopeptidase M20 family)
 73
 0.98
chr4_144434579_144434842 0.20 SMARCA5
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
 94
 0.95
chr11_65480098_65480381 0.20 KAT5
 K(lysine) acetyltransferase 5
 37
 0.95
chr1_149899868_149900298 0.20 SF3B4
 splicing factor 3b, subunit 4, 49kDa
 153
 0.9

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.4 GO:0017085 response to insecticide(GO:0017085)
0.1 0.2 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.2 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.2 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.1 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.2 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.2 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0010664 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.2 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.2 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.3 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.2 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.2 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.4 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.4 GO:0044766 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.0 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.0 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.0 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0031935 regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.0 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.0 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:0016589 NURF complex(GO:0016589)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.0 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.1 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1 0.3 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.1 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC